Genus of fungi
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À la découverte du miso : pourquoi il faut s’y mettre Le miso… son nom commence à nous être un peu familier, surtout à ceux qui fréquentent les restaurants japonais, où l’on sert en entrée l’incontournable soupe miso. Mais de quoi parle-t-on quand on parle de miso ? Cet aliment traditionnel japonais se présente sous la forme d’une pâte souvent foncée. Il est très salé et se compose de grains de soja, le double de grains de riz ou orge,d’eau, de sel marin et surtout, d’un ferment appelé Aspergillus oryzae et enfin de lactobacilles. L’ensemble de ces ingrédients subit une première fermentation, d’environ deux jours. Puis une seconde en condition anaérobie, c’est à dire à l’abris de l’air. Cette seconde fermentation a une durée comprise entre une semaine et deux ans, selon le résultat voulu. Les vertus diététiques du miso C’est précisément cette fermentation qui confère au miso toutes ses vertus diététiques. Tout d’abord, il est stimulant et énergisant. Ensuite, il contient de la vitamine B12, ce qui est assez rare dans le règne végétal. C’est un aliment sans cholestérol et pauvre en gras, mais riche en enzymes, vitamines, minéraux. Il contient en effet une cinquantaine d’enzymes bénéfiques au corps humain. La présence de lactobacilles lui confère des vertus probiotiques : autrement dit, le miso favorise la prolifération de bonnes bactéries dans les intestins, facilite la digestion et favorise l’élimination des toxines. Enfin, il peut aider à surmonter certaines intolérances ou même alimentaires. Des propriétés préventives et curatives Ses propriétés sont à la fois préventives et curatives. Des études menées au Japon lui prêtent des vertus anti-cancer : la présence de mélanoïdines du groupe de mélanines végétales aiderait en effet à ralentir la croissance de cellules cancéreuses. Antioxidant puissant, il peut protèger de certaines maladies cardio-vasculaires et de l’hypertension, atténuer les symptômes de la ménopause, protéger l’organisme d’agents pathogènes. Par ailleurs, il purifie le sang, fortifie le foie et réduit les symptômes de colopathie fonctionnelle. Et je ne vous dis pas tout de ses multiples vertus ! Comment utiliser et conserver le miso Si vous êtes conquis, sachez qu’il est aussi très facile d’utilisation. En effet, vous pouvez tout simplement le rajouter à vos plats préférés, en évitant de saler car le miso l’est déjà beaucoup. Il peut servir de base pour vos bouillons, soupe et vinaigrettes, ragoût ou encore marinade. Il se marie à merveille avec le riz, les vermicelles, le soja et les légumes sautés. Petite astuce : confectionnez vous-même votre vinaigrette et incorporez le miso directement dans votre préparation ! Vous pouvez en consommer jusqu’à 20 grammes par jour, soit l’équivalent de deux bols de soupe. Pour la conservation, c’est au frigidaire. Un allié raisonnable et accessible Le miso est un véritable allié de notre organisme : ne l’en privez pas. Par ailleurs, son coût est très raisonnable. Mon conseil : procurez-vous le miso d’origine biologique (on évite le soja OGM…) et surtout surtout, de fermentation naturelle. Acheter votre premier Miso Blanc pour essayer ! Cet article pourrait aussi vous plaire : Maîtriser son poids autrement, sans régime !
Il y a des portes qui ne devraient jamais être ouvertes. Des tombes scellées depuis des millénaires que l'on n'aurait jamais dû explorer, et pourtant, l'être humain n'a pas résisté à la tentation d'y entrer, quitte à profaner les tombeaux de nos ancêtres. Alors, déranger les m0rts apporte-t-il vraiment des malédictions ? Les m0rts peuvent-ils se venger ? C'est ce que l'on va voir ensemble… c'est parti pour un nouveau moment d'Occulture. --------------------------- Devenez membre de cette chaine pour bénéficier d'avantages exclusifs : https://www.youtube.com/c/Occulture/membership --------------------------- Tous les liens utiles de la chaine (réseaux sociaux, boutiques, chaine secondaire...) : linktr.ee/occulture_ytb--------------------------- Sources : https://en.wikipedia.org/wiki/ https://pmc.ncbi.nlm.nih.gov/ https://www.livescience.com/44297-king-tut-curse.html https://www.historytoday.com/archive/months-past/tutankhamuns-curse https://www.nationalgeographic.com/history/article/curse-of-the-mummy https://www.pnas.org/doi/10.1073/pnas.1305117110 https://ajronline.org/doi/10.2214/ajr.181.6.1811473 https://www.breakingthecycle.education/bolivian-altiplano/los-ninos-de-llullaillaco/ https://www.heritagedaily.com/2025/01/new-evidence-may-reveal-the-source-of-mercury-in-the-tomb-of-the-first-emperor/154358 https://www.globaltimes.cn/page/202501/1327342.shtml Carter, Howard. The Tomb of Tut.ankh.Amen. London: Cassell & Co. Reeves, Nicholas. The Complete Tutankhamun. Thames & Hudson Hawass, Zahi. Tutankhamun: The Golden King and the Great Pharaohs. National Geographic Riggs, Christina. Unwrapping Ancient Egypt. Bloomsbury Academic, 2014 Journal of the Royal Society of Medicine (2002) Price, Bill. “The Curse of the Pharaohs.” British Medical Journal Luckhurst, Roger. The Mummy's Curse: The True History of a Dark Fantasy. Oxford University Press, 2012 McCorristine, Shane. Spectres of the Self. Cambridge University Press, 2010 Dawson, Warren R. “Who Was Who in Egyptology.” Egypt Exploration Society. Ceruti, Constanza & Reinhard, Johan.“Inca Ritual Sacrifices on Andean Mountain Summits.” Current Anthropology Reinhard, Johan. The Ice Maiden: Inca Mummies, Mountain Gods, and Sacred Sites in the Andes. National Geographic, 2005 Wilson, Andrew S. et al.“Stable isotope and DNA evidence for ritual sequences in Inca child sacrifice.”Proceedings of the National Academy of Sciences (PNAS) Brown, Eliana et al.Études toxicologiques sur les momies de Llullaillaco, Journal of Archaeological Science Allen, Catherine J. The Hold Life Has. Smithsonian Institution Press, 1988 Zuidema, R. Tom. The Ceque System of Cuzco. Brill, 1964 Sima Qian. Shiji (Records of the Grand Historian) Portal, Jane. The First Emperor: China's Terracotta Army. Harvard University Press, 2007 Li, Xiaoning et al.“Mercury distribution in the mausoleum of the First Qin Emperor.”Chinese Science Bulletin, 2012 Ledderose, Lothar. Ten Thousand Things. Princeton University Press, 2000 Glob, P.V. The Bog People. Cornell University Press, 1969 Van der Sanden, Wijnand. Through Nature to Eternity: The Bog Bodies of Northwest Europe. Batavian Lion International, 1996 Turner, Robert C.“Iron Age Ritual and Human Sacrifice.” Antiquity Journal Abdel-Hafez, S.I.I.“Fungal flora of ancient Egyptian tombs.” Mycopathologia Saad, M.M. et al.“Microbial contamination in ancient tomb environments.”International Biodeterioration & Biodegradation CDC Reports on Aspergillus exposure in confined archaeological sites. Skal, David J. The Monster Show. Faber & Faber Hogle, Jerrold E. The Cambridge Companion to Gothic Fiction. Cambridge University Press, 2002. Lacan Douglas, Mary. Purity and Danger. Routledge, 1966. Eliade, Mircea. Le Sacré et le Profane. Gallimard Boyer, Pascal. Religion Explained. Basic Books Tylor, Edward B. Primitive Culture Smith, Claire & Wobst, H. Martin. Indigenous Archaeologies. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Discover why Florida's subtropical climate makes Tampa homes vulnerable to dangerous mold species like black mold and Aspergillus. From health risks to professional remediation, this episode reveals what every Tampa homeowner needs to know about detection and prevention. TampaBayMold.net City: Tampa Address: 550 N. Reo St. Suite #300 Website: https://www.tampabaymold.net
Fungi are “nature's biological recycling machines,” says guest Vayu Hill-Maini, a former chef turned bioengineer. That is, they take waste and turn it into good things. Hill-Maini now melds his scientific and culinary skills to create new foods, but also medicines, faux leather, pigments and other valuable products from mushrooms and molds. He uses CRISPR gene editing technology to “domesticate” these fungi – removing off-flavors and increasing nutritional content to make new-age cheeses, burgers, salami, and more. “We call it the DBTL cycle – design, build, taste, learn,” Hill-Maini tells host Russ Altman about his creative process on this episode of Stanford Engineering's The Future of Everything podcast. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu. Episode Reference Links: Stanford Profile: Vayu Hill-Maini Connect With Us: Episode Transcripts >>> The Future of Everything Website Connect with Russ >>> Threads / Bluesky / Mastodon Connect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook Chapters: (00:00:00) Introduction Russ Altman introduces guest Vayu Hill-Maini, a professor of bioengineering at Stanford University. (00:03:33) From Chef to Bioengineer How Hill-Maini's culinary background led him to study food through science. (00:05:23) Building a Lab with a Kitchen Why his Stanford lab combines bioengineering research with culinary experimentation. (00:07:32) What Are Fungi? A primer on yeasts, molds, mushrooms, and their role in food and medicine. (00:10:22) Domesticating Fungi How humans have shaped fungi over thousands of years. (00:14:23) Mushrooms as a Food Source The nutrients, proteins, vitamins, and beneficial molecules found in fungi. (00:16:21) Fungi as Biological Recyclers Using fungi to turn food waste, agricultural waste, and other materials into useful products. (00:18:22) Making Waste-Based Foods Desirable Why taste, emotion, and culinary design matter for sustainable foods. (00:20:22) Engineering Delicious Fungi Using genetics and CRISPR to improve flavor, nutrition, and usability. (00:22:50) Gentle Genetic Tweaks Making small changes to reduce off-flavors or enhance useful traits. (00:23:46) Design, Build, Taste, Learn How the lab moves between kitchen and bench science to improve foods. (00:24:06) Chefs in the Lab How culinary collaborators help guide research and creativity. (00:28:58) Fungi-Based Materials The potential to create textiles, leather alternatives, and building materials. (00:31:03) Future In a Minute Rapid-fire Q&A: sustainability, students, and the promise of fungi. (00:33:25) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Dr. Deb Muth 0:03What are the answers to your child’s chronic allergies, ADHD, or autism?weren’t just in another prescription, but in restoring balance to their body chemistry. Today’s guest has spent nearly two decades uncovering those answers through integrative and biomedical medicine. That’s a mouthful, isn’t it?Helping children heal when nothing else seemed to work.This is the conversation about science, compassion, and changing the future of pediatric care.Welcome back to Let’s Talk Wellness Now. The show where we uncover the root causes of chronic illness, explore regenerative breakthroughs, and empower you with the practical tools to heal. I’m your host, Dr. Deb, your medical detective, and today’s episode is one every patient should hear.My guest is Dr. Anu Usman Singh, Medical Director of True Health Medical Center in Naperville, Illinois, and the owner of Pure Compounding Pharmacy.And for over 17 years, she has been pioneering evidence-based integrative interventions for children with ADD, autism, allergies, and complex gastrointestinal and metabolic disorders. She’s not only a practicing physician, she’s a researcher who’s investigated copper-zinc imbalances.metallonine dysfunction, biofilm-related infections, vitamin D in pregnancy, and hyperbaric oxygen therapy.Dr. Usman serves on the executive board of TACA, and is a faculty member at MAPS, training other practitioners in pediatric integrative care. So get ready for a conversation that will open your mind and heart to the possibilities of when medicine truly becomes holistic.If you guys can insert the ad in here, that’d be great.Well, welcome back. I’m so excited to have Dr. Usman with me today. I have known her for, oh my gosh, 15, 17 years, something like that. We’re aging ourselves. Anju 02:32Oh, yeah, when we were in our 20s, right? Dr. Deb Muth 02:35Yes, exactly. So, welcome back, and I am so excited for you to be here, because you have literally helped thousands of families over the years.But I’d love for you to share a little bit about your journey, kind of who you are, what drew you into exploring integrative and biomedical approaches for helping children and families. Anju 02:58I think my journey is similar to a lot of you out there, the audience. I mean, we’re looking to help our families, and our kids, and ourselves, and I was doing my residency at Cook County Hospital, downtown Chicago, in the 80s.And I thought, oh my goodness, if I could take care of the sickest patients, then I can take care of anybody. So I came from Indiana, and I went to Cook County, and my children, my eldest daughter, started having, severe allergies and asthma, really, really at a young age.And I went to, like, my residence, and I went to my attendings, and I said, this baby is wheezing. And they told me, babies don’t have asthma.And I said, she has all the symptoms of asthma. She has asthma. And I remember with, in her crib, I would just nebulize her, you know, and I was like, what is going on?And I figured out that she had a lot of food allergies, and I was nursing her, eating the foods that she was allergic to, and back then, in the 80s, you know, we didn’t have the internet, we didn’t have Whole Foods, and I just…being a doctor, and I didn’t even know what to do, and I felt so hopeless. And I thought, gosh, you know, I’m a doctor, I have these, like, skills, I have… people I can talk to, and I still feel so… it’s so difficult. And then this… my particular daughter, the oldest one, her name is Priya, and she developed severe, asthma, and I couldn’t figure it out. She was in junior high. Every time she would walk into the lunchroom, she would have a severe asthma attack.And I’ll be like, what’s going on? What’s going on? I kept her home over the weekend, she was better. I sent her back to school, she was bad again.And we figured it out that it was other people eating peanuts. Dr. Deb Muth 04:54Severe peanut allergy. Anju 04:56And I went to the school, and I said, she…can you, like, put her somewhere else? Can… they said, oh, no, that’s not fair to other kids and their food. And this was in the 90s. Dr. Deb Muth 05:10Yeah. Anju 05:10And so, I just…You know, my heart goes out to families who are struggling to find answers for their kids, and my daughter Priya, the one I told you about, she ended up passing away from a peanut allergy.And so, I’ve just… Dr. Deb Muth 05:26Yeah. Anju 05:27My heart goes out to parents and my own kids and their illnesses.And so I just started working with families, with kids, andIt just kind of grew from there. Dr. Deb Muth 05:40Yeah. Yeah. Yeah, and I think being a mom who went through that yourself, and…was seen but not heard, and turned away from the traditional medical community, you’re forced to start finding answers on your own. And we always feel like we’re on an island by ourselves in the medical world when we’re doing that. Anju 06:01Yeah, I, it was really hard when I found out, you know, about…Integrative medicine, and just different…ideas and approaches to diet and supplements, I thought, how come I wasn’t trained in any of this?And… Dr. Deb Muth 06:21So angry when I learned some of the things that I learned in the beginning. I was like, same thing, like, how did they not teach us this? And then I think, you know, it’s my fault, was I asleep, was I not paying attention, whatever. And then you just realize, like, there’s this whole part of the human body.That they just didn’t teach us. Anju 06:42Yeah, so then I… I, probably like you, we had to learn it on our own. There weren’t, like, classes or any way to learn this stuffAnd I just reached out. There’s a clinic that,I don’t know if you’ve heard of the Pfeiffer Treatment Center? Dr. Deb Muth 07:00No. Anju 07:01Do you know Carl Pfeiffer from the attendees.He has a clinic called the Pfeiffer Treatment Center in New Jersey. It was called the Princeton Brain Bio Center. Dr. Deb Muth 07:12And in the 70s, they did orthomolecular medicine for patients with ADD. Anju 07:18And schizophrenia. Dr. Deb Muth 07:20Mmm… Anju 07:21and depression.And they used to categorize them in 3 categories, and at the time, they called them histopenics, histidelics, and pyrolurics. Dr. Deb Muth 07:31Okay. Anju 07:32Histapenix were low histamine patients.Delix were high histamine patients, and pyrolurics were their own kind of category. We added another category of copper-zinc imbalances, and then we would categorize that population into high histamine, low histamine, pyrolurics, and copper-zinc.Now we talk about under-methylation, over-methylation. Sure. So, under-methylation is the, you know, the high histamine people, they can’t clear the histamine. And the over-methylators are, you know, what we call about low histamine now.And, and then pyrolurics and copper zinc. So…I lost my train of thought, but in the 80s, when I was going through this, in the 90s, I reached out to the Pfeiffer Treatment Center.He’s like, can I calm and just hang out and, like, see what you guys do? Because I need some answers.And I started working there and, started doing research on copper-zinc imbalances, and I did it in children with autism.And that’s how people started coming to me, and I kinda got, like. not famous, but I, you know, the word spread about, okay, we could talk about it, and Dr.Walsh was the, you know, PhD there that did a lot of the research, so we worked together for 8 years. Dr. Deb Muth 09:05Isn’t it crazy to think that we knew about histamine issues way back in the 70s? You know, I got the pleasure of being trained by, environmental medicine doctors. Dr. Wayne Konetsky and Glenn Toth taught me about environmental medicine, and what we called histamine issues that we call it today, mast cell, right? But when I was learning in the early 2000s, it was labeled as chemical sensitivity. And so it was just people that would react to everything, and we really didn’t know why, and they didn’t necessarily have this very specific allergic reaction, but we knew they were reacting, and we would try to treat them, to lower the histamine way back then. And it’s taken all these years, 25 years, to get to a point where we understand mast cell activation now, and histamine issues.And it’s really sad to me that it’s taking this long for us to identify things.And we’ve all got our journey, and I loved back in those days, too, because as I learned, I would call people up and say, hey, I just got a patient from you, and they told me this great story, and I have other people, can I come see what you were doing? And back then, everybody was very open. They were like, yes, please, come, learn. Now everybody’s like, oh, we can’t teach you, we can’t give you our secrets, but…Or pay me $20,000 to come learn with me. But back then, I mean, everybody was just… we were all in the same boat. We were all just trying to learn from each other. Anju 10:36Oh, yeah, oh yeah, and any bit of knowledge you got, you’re like… Dr. Deb Muth 10:41Yes. Anju 10:41God, you know, I learned this piece, and… Dr. Deb Muth 10:43Hmm? Anju 10:44We just kind of built from that. I keep thinking about back then, you know,the under-methylators, over-methylators, copper, zinc, and then I learned about metals.And then, as a physician, I was like, oh, okay, well, there’s mercury in vaccines, there’s aluminum in vaccines, and now I’m seeing these high levels. Dr. Deb Muth 11:04In my patients, now what happens? Anju 11:07And then we started, kind of, trying to get the word out about those things. Dr. Deb Muth 11:13Yeah. Anju 11:13And in 2000, a lot of the people that I knew put out a paper about, you know, mercury. Dr. Deb Muth 11:22And then… Anju 11:22And we all got on the Mercury bandwagon. Dr. Deb Muth 11:25Yes. Anju 11:26And did that for a while, and then we started learning about other things, like mitochondrial issues in chronically ill people, and these chronic infections, like Lyme disease, and so… and then now, you know, understanding mast cell activation, cell danger response. Dr. Deb Muth 11:44On endocrine, and adrenals, and hormones, and… Anju 11:48Yeah. Dr. Deb Muth 11:49biofilms. Anju 11:50Biofilms, I started talking about that in 2007. Dr. Deb Muth 11:54And so then… Anju 11:56It just… it just kind of keeps adding, and keeps adding, and keeps adding, and it’s like…Sometimes you think, how come I didn’t know about this back then? But I feel like it’s a process. Dr. Deb Muth 12:06It definitely is a process, and it’s amazing to seehow many people are researching different things, and they’re all, like, putting a piece of the puzzle together. And I think this is really important for our listeners to understand, is when you see a practitioner and they don’t have all the answers, this is why. It’s very complicated, it’s not black and white. And I’ve had patients over the years say to me, well, why didn’t you say this to me 6 months ago? And the truth of the matter was, I didn’t knowabout it 6 months ago. Like, all of this stuff is just… it’s evolving constantly, and when you’re a practitioner like Dr. Usman and myself, you are learning every single day. Our training has never stopped from the day we stepped into integrated medicine, and you just… you keep learning new things, and sharing new things, and talking to new people, and that’s what expands our knowledge base. Anju 12:57Yeah, the more I learn, the less I feel like I know. Dr. Deb Muth 13:01Yes, me too. Every time I go to a conference, I’m like, how did I not know this? How am I stupid? And I know we shouldn’t say that word and call ourselves that, but sometimes you feel like that. It’s like, how did I not know? Anju 13:14Or you’ll see a patient, and you’ll look at them, and you’re like, how come I didn’t realize this about this particular patient? Dr. Deb Muth 13:20Yes. Anju 13:21Yeah, they present differently, see things differently. I think that’s why it’s good to find a doctor that you trust and that you can work with, because it’s evolving. Dr. Deb Muth 13:31Yes. And, you know, we have those patients that they come, and I get those. I call myself, like, a tertiary care center. Anju 13:38You know, you get those patients that have been everywhere, and seen every doctor, and then they’re like, you’re my last hope, you’re gonna solve all my problems, and…I say to them. We’re a team, like, we’re gonna solve these together, but it takes time for me to unravel this puzzle. Dr. Deb Muth 13:54Excuse me? Anju 13:54And it… and sometimes, you know, there’s a few hits and misses along the way. Dr. Deb Muth 14:00Yup, but if. Anju 14:00If we keep at it, you know, we also say it’s a marathon, not a sprint. Yes. You know, if we keep at it, we can kind of figure it out together. Dr. Deb Muth 14:09Yeah, and a partnership, for sure, because without the feedback of the person you’re working with.understanding, like, we do this, and this happens to you, it’s very complicated as a practitioner to then be able to figure out, what do we do next? I see more and more clients these days, they come in and they just want to ask me within the first 5 minutes of, what am I changing? And I’m like, I have no clue yet. Like, you have to tell me what’s happened since the last time we did something, and then we have to look at labs, and we have to look at this, and we… it’s a synopsis.that we have to look at. You know, it’s not that black and white for us to be able to put the pieces together for them. Anju 14:47I think my most successful patients are the ones who are able to communicate with me.Their ups and downs. Yeah. And they also use their own intuition. Help me guide them. Dr. Deb Muth 15:06Yeah. Anju 15:07So, there are some people that they just hear, you do it, and you tell me.There are people who try to tell me everything. Dr. Deb Muth 15:15Okay. Anju 15:15Say, I want you to do this, do this, do this. Dr. Deb Muth 15:17Yeah, so I was like, okay. Anju 15:19I can do those things, but, you know, like. Dr. Deb Muth 15:21Yep. Anju 15:22think about blah blah. But, like, this… that collaboration.and, intuition. I kind of feel like even thoughI’ve trained allopathically as a traditional medical doctor. I feel like as I learn, I learn that being open and,Letting go of fear. Dr. Deb Muth 15:46Yeah. Anju 15:47And, not trying to jump on every, like, new thing, and being. Dr. Deb Muth 15:53consistent. Anju 15:54and diligent. really helps. Dr. Deb Muth 15:58It helps a ton. We see that, too, you know, the latest…Instagram influencer that’s talking about the latest topic, and all of a sudden, everybody sees themselves in there, and they must have that, but not realizing putting those connections together. It’s like when MTHFR came out, right? We were all so excited that this was going to be the detox gene.And then we learned so much more about genes, and now MTHFR is very popular again, and everyone’s talking about it, but they don’t understand how some of those other genetics fit together. And if you don’t understand that, we’ve all done it, we’ve all made people worse instead of better, sometimes when we’ve given too many methyl groups together, or this supplement without this support before we knew that there was another gene that we had to support for that.And I think it’s really important for people that are listening to us today talk about this, is don’t just jump on the bandwagon. Like, you really want to work with somebody seasoned who understands how all these pieces fit together. Anju 16:57Yeah, and I think that’s what individualized medicine is about.And there is no magic here, a magic bullet.I think that example of MTHFR is really good. Now, President Trump talked about Leukovorin. Dr. Deb Muth 17:14Yes. Anju 17:15in, and, you know, he’ll get up and say something like, leukovorin cures autism.And then the rest of us are like…Did you just say that? Dr. Deb Muth 17:26Yep, he did. Anju 17:30It’s folinic acid, it’s calcium folinic acid, it’s been around a long time. We’ve been using it for 20 years. Dr. Deb Muth 17:37Yeah. Anju 17:38But it does help a subset of people who potentially have what we call cerebral folate deficiency.And some of those people are misdiagnosed as autism. Dr. Deb Muth 17:50Yeah. Anju 17:51So, are you treating autism, or are you treating cerebral folate deficiency?same thing I could say about… I have a lot of cases of kids who recovered from autism.and severe ADHD using chelation type of. Dr. Deb Muth 18:06up. Anju 18:06Approaches, or detox approaches.again, did we treat their ADD and their autism, or did we treat their lead…Toxicity or lead burden, and their symptoms of those things got better. Dr. Deb Muth 18:20Yeah. Anju 18:20So, like, to put a big, like, a label like, oh, ADD on something, or autism on something, I think it does a disserviceTo the individuals, because it’s such a broad issue. Dr. Deb Muth 18:35It is, and I think the diagnosis has gotten to be much more popular these days.And yes, thank goodness we’re getting better diagnostics, but sometimes we’re getting over-diagnosis, or like you said, it may look like one thing, but it could be something else, but because it looks like autism, they’re going to get labeled with autism.And in some respects, that’s good, they can get more services that way, but sometimes we’re missing the actual picture of it. Can you talk a little bit about how autism is different than the cerebral folate deficiency? Anju 19:11Yeah, so there are some people that make an antibody to their folate receptor. Dr. Deb Muth 19:18Hmm. Anju 19:20So, to get folic acid into your cells, there’s a receptor on your cells. Dr. Deb Muth 19:25And then the folate has to bind to it, and then it lets it enter into the cells. Anju 19:30And there’s these receptors that allow folic acid to get into your brain.Now, you and I know when you put folate in your brain.On one end of the folate cycle, you help make more neurotransmitters. You’ll make something called BH4, and that’ll help make serotonin and dopamine, and then norepinephrine and epinephrine. So folate is really important for making your neurotransmitters, folate and B12.On the other end, it’s like, another cycle on the other end of folate is our methylation cycle.And methylation is so important for our RNA and our DNA, and making choline, phosphatoly choline, and making creatine for speech.And helping us with all the precursors for detoxification.So without folate in our brain, we can’t make our neurotransmitters efficiently, we can’t break them down efficiently, and we can’t detox our brain.Imagine what that will do to your brain. Dr. Deb Muth 20:36Yeah, Anju 20:37And you will see symptoms like speech delays, cognitive delays, processing issues, poor attention.All of those things. Excitation, anxiety.All of those, and so if the folate isn’t getting into the brain efficiently, then we’ll have all these symptoms, and we’ll end up with diagnoses like these. Dr. Deb Muth 20:59Yeah, so is there a way that people who are listening to this can request a test to see if they make this antibody to folate, or is it more of a diagnosis of exclusion? Anju 21:14That’s a great question. When I first started doing this, like, 20 years ago, there was, like, a university that was doing this.studies, and it was Dr. Quadros. He was the guy, and we would take samples and send them to his lab, and he would tell us about these blocking and binding. Dr. Deb Muth 21:30folate antibodies. Anju 21:32And if patients had positive blocking or binding folate antibodies, we would follow his protocol. And he’s done papers on patients with severe autism.Where he found these folate antibodies, and then did spinal taps on the kids, and they were associated with this cerebral folate deficiency. the cerebral… spinal fluid.And in his papers, he gave .5 to 2 milligrams per kilogram of calcium folinic acid, which is leukovorin. It’s a vitamin. And over a 6-month to a 12-month period.The majority of those patients improved drastically.Some of them regained speech, and some of them lost their autism diagnosis. Dr. Deb Muth 22:26Because they never truly had autism. Anju 22:29Well, they have autism symptoms, and that’s what autism is, but we call it autisms. Dr. Deb Muth 22:36Yeah. Anju 22:37And so now, like, we need the research to categorize these people. You know, what percentage of autism is cerebral folate deficiency? Yeah. What percentage of autism is, heavy metal. Dr. Deb Muth 22:51Bourbon. Anju 22:52And what percentage of autism is Clostridia overgrowth, or… Dr. Deb Muth 22:57Hmm. Anju 22:57microbiome… Dysfunction, and then there’s overlap. Dr. Deb Muth 23:01Right, yeah, Lyme and mold and viruses. Anju 23:04and infections, and you can see… Dr. Deb Muth 23:07injury from medications and things like that that happen, or birth traumas. Yeah, I mean, it’s not… it’s not as simple as what people think autism is.Why do you think that we’re seeing so much more autism today than when you and I were kids? We didn’t see this that often. I know environment has a lot to do with it, but do you have a couple of things that you suspect are contributing to the rise of autism these days? Anju 23:38Yeah, I mean, that’s a million dollar question. Dr. Deb Muth 23:40Right. Anju 23:41And, just because I work with children, you know it’s not just autism that’s epidemic, and yeah. Dr. Deb Muth 23:49You know that. I mean, it’s… it’s probably… if you add all the epidemics that are happening to children. Anju 23:54Autism still supersedes it.Now it’s 1 in 33s, 1 in 35 boys, I mean, it’s…children. It’s really sad. When I was in med school, it was 1 in 10,000. Dr. Deb Muth 24:10That’s crazy. Anju 24:11What’s causing it? I mean, obviously it’s multifactorial. Dr. Deb Muth 24:15Yeah, 80,000 chemicals in the environment that we never had before. Anju 24:20I, I, I, look, I’ve… 219 million. Dr. Deb Muth 24:26Oh my gosh. Anju 24:27I looked it up today. Dr. Deb Muth 24:29119 million different chemicals in the environment. Wow. Anju 24:33We don’t know how many of those are super toxic. Dr. Deb Muth 24:36Yeah, and we don’t know what they do together. Anju 24:38A lot of them were, like, before, like, grandfathered in and all of that.Yeah, it’s really crazy about the chemicals. So, chemicals… I kind of… feel like…you know, this burden of all this, it’s not just on our children, it’s on our mothers. Dr. Deb Muth 24:56Yes. Anju 24:56oh my gosh, the moms of these children that… And they don’t even realize it, you know, we’re just so happy to be pregnant and have a kid.So I think it really, really starts with that piece. Care, good prenatal care, yeah. Yeah, and not just what we think is prenatal care, taking your prenatal vitamins. Dr. Deb Muth 25:18Yes. Anju 25:19And going to your gynecologist, but what you and I think is prenatal care, you know, before you get pregnant, let’s detox, let’s clean up our diet, let’s get rid of those chemicals, let’s make sure we’re not in a moldy environment.You know, let’s do our due diligence, clean air, clean water, clean food, sunshine. When I did my residency at county, I don’t think I saw the sun for 3 years. Dr. Deb Muth 25:44How?Yeah. Anju 25:46it’s just that intense, and I was pregnant twice, and my eldest hasthe allergies and asthma. Number 2 is type 1 diabetes and mold sensitivities and allergies and asthma. Number 3 has severe chemical sensitivities, mast cell activation,Hormonal issues. Dr. Deb Muth 26:09Yeah. Anju 26:09And… number 4 is my… Golden, baby. Dr. Deb Muth 26:15And those three, you know, those years that you’re there, and you’re not seeing the sunlight, there’s vitamin D deficiency, and we don’t talk about vitamin D that much during pregnancy.I still am appalled that we’re giving folic acid these days during pregnancy instead of folate, but… Anju 26:36Folenic, or methylfolate? Dr. Deb Muth 26:38Yeah, nothing. So, when, when you,discovered vitamin D in pregnancy, and it’s linked to neurodevelopment outcomes. How did you stumble across that? Anju 26:50Well, in… when I started working on Copper Zinc, Dr. Walsh and I would go to the, like, DAN conferences.Yeah. At the time, and it was interesting, because DAM conferences were a collaboration between parents.And practitioners, and researchers. Dr. Deb Muth 27:10Very unique for. Anju 27:11That’s how that new IACC committee is. It’s a collaboration of parents. Dr. Deb Muth 27:17Hmm. Anju 27:18Practitioners, researchers, And individuals with autism. Dr. Deb Muth 27:25Yeah, so for those of you who are listening to us, it’s… we’re talking about the Interagency Autism Coordinating Committee that Bobby Kennedy just put together. It’s called IACC, and they are on a mission to try to do the research to figure out what’s causing autism. Anju 27:43Yeah, and not just causing it, like, these people have been living it, most of the people on that committee have been living it, and their whole lives, for some of them.And being able to bring forwardlike the question about vitamin D, we started seeing a lot of patients in Minnesota. Dr. Deb Muth 28:04Mmm. Anju 28:05who were from Somalia. Dr. Deb Muth 28:08Okay. Anju 28:09Who were… it was, like, 1 in 4 families with kids with autism.And the theory was that the vitamin D levels that they get in Somalia versus the vitamin D levels that the moms get in Minnesota. Dr. Deb Muth 28:27Hmm? Anju 28:28Affected the immune system. Dr. Deb Muth 28:31Yeah. Anju 28:32predispose them. So there’s a few papers on that. Dr. Deb Muth 28:36Yeah, that’s a… I mean, it would be a very significant difference, and when you’re thinking about genetically, like, what their culture, who they are as a species.was used to and adapted to with the sunlight and different things from a different region, geographical region, and then they moved to a new geographical region, that can take decades before the body adapts and readjusts.to that new environment. We don’t think about those things in…traditional medicine, and conventional medicine, as most people know it, but we do in functional medicine. Anju 29:14Yeah, so again, the clinicians were bringing this up, like, why am I seeing so many families? Dr. Deb Muth 29:18Yeah. Anju 29:18Then let me go to the… and then in the think tank, the vitamin D researcher said it’s vitamin D. Dr. Deb Muth 29:24Yeah. Anju 29:25And then they started researching it, and it was almost like a backwards… backwards. Dr. Deb Muth 29:31Thank you. You know, they didn’t first… Anju 29:33Think it. Dr. Deb Muth 29:34Think about it, yeah. Anju 29:35Until you start seeing… and that’s why I think that, like.clinicians like you and me, who are… I consider us on the front lines. We’re the front lines. We are seeing… we’re seeing this epidemic unfold. Dr. Deb Muth 29:46Yes. Anju 29:47front of our eyes, we’re seeing, like, the gut issues and the severe inflammation. We’re seeing the autoimmunity, and now they have to study it. Dr. Deb Muth 29:57Yeah. Anju 29:57They have to study this. They really, really, we really need, we really need protocols, we need tools, we need things that you and I have been figuring out anecdotally with our colleagues over the years, and, oh, how do we treat yeast? How do we treat Lyme? How do we treat metal burden?For this podcast today, I wanted to talk about low-level lead exposure, because for me.1 in 3 children have a lead level, above 5. 1 and 3. Dr. Deb Muth 30:31Yeah, that’s very high. Anju 30:33800 million children. Dr. Deb Muth 30:36And let’s clarify this, because the first thing people are going to think of is, what are they eating? They’re not eating lead paint to get this. That is not what’s happening here. They are getting lead from someplace else, and their bodies are not able to detox this. Anju 30:53And the reason I’m bringing this up is because when I was in residency at County in the 90s, I ran a… I worked at a lead clinic. Dr. Deb Muth 31:01And back then. Anju 31:03When we looked… we just diagnosed lead toxicity, the level was 60. Dr. Deb Muth 31:10Their level had to be 60 to diagnose them. Anju 31:13Correct. Dr. Deb Muth 31:13Oh my gosh. Anju 31:14And that’s when we would treat.And back then, there was a study, it’s called the TLC study, where they used DMSA, which is a drug to lower lead.And our goal was to get it from 60 to 20. Dr. Deb Muth 31:33And was the normal range the same back then as it is today? Anju 31:37The normal range has gone from 60 to 40 to 20 to 10 to 5 to 3.5.But you and I know I’m the normal range. Dr. Deb Muth 31:47Yes. Anju 31:47Zero. Dr. Deb Muth 31:48Zero. Anju 31:50So… so again, in my… in the lead clinic, we were given DMSA, and we got the lead from 60 to 20, and the number one thing was to get rid of the lead in the environment. Dr. Deb Muth 32:02Yeah. Anju 32:03But we haven’t evolved since then.Because in that study, It did not improve cognitive abilities. So if you think about what lead does, it causes attention issues, slow processing, it affects hearing, it can cause hyperactivity, it can cause impulsivity, it can cause aggression, it can cause constipation, it can cause hypotonia.So if you think about all these kids with ADD and autism, how many of them have low-level lead exposure from the lead pipes? In Chicago, it’s a big, a big problem. Dr. Deb Muth 32:37Yeah, Milwaukee. Anju 32:38Everybody thinks Flint, Michigan, but Flint, Michigan is not the only place. Dr. Deb Muth 32:42Right. Our infrastructure is so terrible, it has not been updated, and even though you might look in your house and you might see a white PVC or plastic pipe, what’s coming under the ground to the house in the cities is usually still lead. Anju 32:58Right. Right. Dr. Deb Muth 33:00Yeah. Anju 33:01So, I guess the point is, is that…the… the idea of, like, studying this. So, again, they study this, and they say, well, we’re not going to treat low-level lead exposure because it doesn’t improve their cognition.But did they really treat it? Dr. Deb Muth 33:18Right. We got it from 60… we got it from 60 to 20. Right. But when I know, where is the lead hiding? Anju 33:24So high. Look at the bones, it’s gonna be coming out. It’s gonna be coming out, especially during puberty. What happens to some of our kids during puberty? They just go a little wonky. Comes out again during menopause. Dr. Deb Muth 33:38Yes. Anju 33:39I don’t know, male menopause, too. Like, we’re all losing bone mass then, and our lead is coming out, our blood pressure goes up. So, again, these are some of the areas that I think, like, really need some… hard… looks. Dr. Deb Muth 33:53Right, yeah. So, what are you hopeful about this committee? Like, are you hopeful that this committee is going to be able to research some of these big things, and we’re really going to be able to find answers around some of the functional things and the biochemical things that we see, you and I know happen in the body, that might give some standardization and education to practitioners in the future. Anju 34:23Well, I think this committee understands the scope of the issues.And they’re coming from different perspectives, like I mentioned, research. Dr. Deb Muth 34:33Yeah. Anju 34:35really highly qualified MDs. MDs like you and me, who have been on the front lines. moms. Dr. Deb Muth 34:43Yeah. Anju 34:44dads, patience, And so, the strategy would be to get, again, their input, and then…get the places… people in places to do their research. And even make some guidelines and some, like, you know, thoughts about what we want to put out there. Dr. Deb Muth 35:05Yeah. Anju 35:05You know, how do we want to strategize for… Dr. Deb Muth 35:08Prevention. Anju 35:10Like, the pre-pregnancy thing. Dr. Deb Muth 35:12Yeah, I’m really hopeful that this doesn’t become a… political football,And it doesn’t get taken away if the administration changes or whatever, because people need to understand that this kind of researchthis is going to take decades for people to do. Granted, we have AI, and AI can help a little bit and get some things quicker.But trying to figure out all of these nuances to why the body does what it does is not gonna be, like, next week we’re gonna find out that this was the single cause, and I know a lot of people, they’re afraid of the vaccines, and that’s gonna be the sole answer.And that has a piece of it, but it is just a small piece of it for some people larger, but at the end of the day, that’s not what this is about. This isn’t about just labeling one thing that is the cause of autism, because it is not one thing. It is so multifactorial. Anju 36:09And I think that whole cause, I know,A lot of money has gone into. Dr. Deb Muth 36:16Yeah. Anju 36:16looking at that. They’re looking for the gene, right? The gene that causes it, and… Dr. Deb Muth 36:23answer. Anju 36:24They have not… they’ve spent millions of dollars looking for this.And it’s not gonna pan out. It’s not. Dr. Deb Muth 36:33I’m not. Anju 36:34pan out. It’s more complex, like we’re talking about. Dr. Deb Muth 36:38Yeah. Anju 36:38And, I do think that sometimes, you know.Even though, like, politically, it seems like it’s a political topic, but it has zero to do with politics. Dr. Deb Muth 36:52Yeah, exactly. This is our children. This is the future of our country, the world. I mean, America’s not the only place that has kids with autism. I mean, this is the future of humanity. If we don’t figure out what’s injuring our children, there will not be a humanity that you and I have seen. It will be different. And, and this is important, we owe it to the future of our generations, we owe it to our children to figure this out and clean up our environment, and make it safe for everybody. Anju 37:24Yeah. Clean up our air, clean up our water, clean up our food… Dr. Deb Muth 37:29Yeah. Anju 37:30You know, our lifestyle a little bit, but… Dr. Deb Muth 37:32hoodie? Anju 37:33It’s… it’s… it’s everywhere. I travel all over. Dr. Deb Muth 37:36Bye. Anju 37:37Consult with doctors in different countries, in Italy, in India, Bulgaria, Romania… Dr. Deb Muth 37:46Yeah. And. Anju 37:48we’re going to Australia for med maps to treat doctors in, in April. And it’s a problem everywhere. Dr. Deb Muth 38:00Yeah. Anju 38:01really big problem, and it affects everybody. Even if you don’t have a child with autism or a grandchild with autism, it’s still affecting families, becauseI kind of think of ADD as being on the spectrum, in the sense thatI think the same kind of positive issues that lead to the autism are causing the ADD, just to… you know, your genetics are playing a little bit of a different role, whatever… whatever protection you have is a bit more there, but we’re seeing kind of, like, similar metabolic… issues in our ADD population. Dr. Deb Muth 38:43Yeah. Yeah, there’s so many different levels of this, and it does affect everyone. Like, I think everybody knows… a family or someone in their classroom or their school or their community that’s affected by, definitely, ADHD, Asperger’s, autism, all of those things, whether you’re high functioning or not functioning or whatever.everything is affected. The school system is affected, your social circles are affected, your families are affected.the healthcare is affected. I mean, everything is affected. We owe it to our families and our communities to help people try to figure this out. Anju 39:22Yeah, and I think even if it’s not ADD, or ADHD, or autism we’re talking about, or even OCD, anxiety, depression, I mean, you know… Dr. Deb Muth 39:33Candace? Anju 39:34Any kind of chronic illness that people are dealing with has underpinnings of these kinds of, you know, issues. Dr. Deb Muth 39:43Yeah. Anju 39:44Any autoimmune issue? That’s great. Dr. Deb Muth 39:48inflammatory syndrome that we’re seeing these days, I mean, the pants-pandas piece, the biofilms, the strep, I mean, our environment is just so laden with infections and biofilms, and And, you know, when you and I first were learning about this, we never thought anything could cross the blood-brain barrier, right? It was pristine, there’s nothing getting in there unless you could drive it in there, and now we know that’s different, and now we’re seeing bugs in the brains of people who have had Alzheimer’s disease and dementia because they’ve donated their brains for research, and we can see what’s crossing the blood-brain barrier, and it’s really scary. Anju 40:24Yeah, yeah. There’s a lot of things we don’t know. Remember when we just found out that they… the brain had a lymphatic system? Dr. Deb Muth 40:33And that wasn’t About, what, 5, 6 years ago? 7 years ago, maybe? Yeah, not that long ago. Anju 40:38You’d be like, why wouldn’t the brain have a lymphatic system? Dr. Deb Muth 40:41Yeah! Yep. Anju 40:44Yeah, so things get in and out. Dr. Deb Muth 40:46They, they definitely. Anju 40:47You know, they get in easier than they get out, I think. Dr. Deb Muth 40:50I agree, I think they do, for sure, for sure. You know, when you’re talking to a family who’s undergoing issues like this, what’s the role, do you feel, in personalized nutrition to help them make things better? Anju 41:10I kind of go through, like, a little bit of a start here, start there, and then do this. I always start, number one, I say, okay, you gotta clean up your environment, because… We gotta do that. Dr. Deb Muth 41:24But that’s a… Anju 41:24process. And then number 2 for me is cleaning up the diet. And then, when you say personalized nutrition. To me, figuring out what is a good diet for the individual. Dr. Deb Muth 41:38Makes it a little bit difficult. Yeah. Anju 41:41I mean, there is, like, healthy eating concepts, where, you know, eat upside-down food pyramid kind of concept, I guess, is the new one, but whole foods, whole grains, organic as much as possible, especially for animal products, good fats, avoiding, you know, hydrogenated oils, and those seed oils, and… Just some basics, and then individualizing for my patients, a lot of people with any kind of autoimmune condition, and we kind of put autism in that neuroimmune, autoimmune, inflammatory That, gluten-free, dairy-free, and sugar-free kind of go there, like, as a given. If there’s a lot of gut issues, a lot of our folks have oxalate issues. And then we have to sometimes do low or limited oxalate diets. Many of my patients can’t convert glutamate to GABA efficiently. Dr. Deb Muth 42:44Yeah. So, high glutamates associated with OCD, and kind of looping or repetitive behaviors. Anju 42:51So, low-glutamate diets. And then some of my patients have SIBO, and then we do the low FODMAPs diet, and then some of my patients have messel, and we’ll do the fail-safe kind of concept with the fail-safe diet, so nutrition can get a little bit complex for certain people, but there are some basics, and then there are some, like, more of… Individual, kind of, diet approaches. And then there’s supplementation. There’s some things that I call foundational. For me, certain things most people need that have a chronic illness. Dr. Deb Muth 43:26Yeah. Anju 43:26Vitamin D3 is one of those. Omega-3s are another one for most. And then, because I did a lot of research on copper, zinc, I think 3 mineral… 4 minerals. I feel like people underdo minerals. They’re so important. Every single enzyme has a mineral cofactor, so… zinc is really important for my population with autism and ADD. 99% of them had high copper or low zinc in. Dr. Deb Muth 43:58Wow. Anju 43:59Over 400 patients that we tested. Dr. Deb Muth 44:01Wow. Anju 44:03And, magnesium.So, zinc, magnesium, and then the other two minerals I really like are selenium for glutathione. and molybdenum for sulfation, and glycolysis. So… So those are kind of my foundational pieces, and then I like to work on the gut next. So, from a nutritional perspective, prebiotics are my new favorite. Dr. Deb Muth 44:29Yeah, we go in and out with prebiotics, probiotics, postbiotics. Anju 44:34Yeah, exactly, symbiotics. Dr. Deb Muth 44:36Yes, exactly, exactly. Anju 44:38demos, and… Dr. Deb Muth 44:40Yeah. Anju 44:40So yeah, biofilm busting, and all of that, so… And then I go into my other nitty-gritty stuff, like you probably do. Dr. Deb Muth 44:47individualized, right? So, you created, True Healing Nature, a supplement line, a supplement company, correct? Anju 44:56Yeah, True Hing Naturals. Dr. Deb Muth 44:58Truly Naturals, okay. Anju 44:59True, he is hard. Dr. Deb Muth 45:01Oats! Anju 45:01True! Dr. Deb Muth 45:01Healing natural. Got it, sorry about that. Tell us a little bit about what made you decide to create a supplement company. Was it because you couldn’t find formulations that you wanted? Couldn’t find clean products? That’s a big problem for people, for sure. Anju 45:19Yeah, a little bit of both. I told you that my kids were really sensitive, they had a lot. Dr. Deb Muth 45:23I know. Anju 45:24And when I would even try to give them things like ibuprofen. Dr. Deb Muth 45:28or Benadryl. Anju 45:30For allergies, they couldn’t tolerate the products that were over-the-counter. Dr. Deb Muth 45:35Yeah. Anju 45:35So, in 2007, I opened a compounding pharmacy so I could make things clean for them. Dr. Deb Muth 45:42Yeah. Anju 45:43And I thought it was so valuable. And so then I started seeing, like, certain issues with my patient population, for instance, say, mitochondrial issues. So, I would compound a mito cocktail. in my pharmacy. And then I had True Healing Naturals manufacture it, so I didn’t have to have patients get it compounded. Dr. Deb Muth 46:08Got it. Anju 46:09So that particular product’s called Mito Rescue. Okay. But then, I started… I do a lot of oats testing. Organic acid urine tests. Dr. Deb Muth 46:19Yeah. Anju 46:20But there’s, like, a marker on there for, oxalates, and I saw a lot of patients with oxalates, and oxalates inhibit some… an enzyme called, pyruvate decarboxylase. And that basically means you can’t take your carbs and turn them into energy. Dr. Deb Muth 46:38Okay. Anju 46:39So, if I saw this pattern with high oxalates and high pyruvic acid, I knew that that enzyme wasn’t working very well, and that enzyme is B1, molybdenum, and biotin dependent. So, I started compounding doses of that. And then I turned that into a product called Motor Connect, because high doses of biotin help with connectivity in the cerebellum. Dr. Deb Muth 47:08Got it. So, I did come… kind of start with the compounding pharmacy, try it, use it, and then turn it into. Anju 47:17products, and I have one for copper-zinc imbalances called True Minerals. Dr. Deb Muth 47:21Yeah, to fix the problems that were not commercially available. Could you talk a little bit for people who don’t understand what a compounding pharmacy is? Anju 47:32So, when you guys go to a pharmacy, you, you know, you send a prescription, and it’s already, it’s manufactured, and you get it. Well, a compounding pharmacy actually makes that for you. So they get the raw ingredients, and then they make that prescription. So it’s still prescription-based. But, for instance, say, I want Nystatin. And I go to Walgreens or CVS, and the nystatin there is a liquid, and it has yellow dyes and sugar. Dr. Deb Muth 48:02Yep. Or it’s a title, and it’s red. Anju 48:04or it’s bread, and a tablet, and I, like, oh, I want to treat the yeast, but I don’t want to use this. So I sent my nystatin prescription to a compounding pharmacy, and it’s Nystatin. That’s what you got. Yep. Dr. Deb Muth 48:17disappear. Anju 48:18So, pure compounding pharmacy, it’s pure, it’s pure stuff. Especially for our mast cell people. They’re so sensitive, and, you know, my kids are all mast cell, and so I just find that excipients, some people will say, oh, this doesn’t work, and I said, it’s probably the excipient that’s stimulating your mast cell activation. So, yeah. So, compounding pharmacies, You know, with all the big, kind of. conglomerates and big companies, they’ve become… they used to be, like, mom-and-pop kind of places. And my pharmacy is like that. It’s just… it’s… it’s a few of us, and we… we do it, and it’s nothing big or fancy, but we get the job done. So, we compound things like methylcobalamin injections, hydroxycobalamin, low-dose naltrexone. Different things for chelation. So, it’s nice. I love having it. Dr. Deb Muth 49:11Yeah, the compounding pharmacies really have made a huge difference for people who are sensitive. You know, so many ingredients are contaminated with corn and gluten and soy and dairy and all the big things that we want to stay away from, especially if we’re trying to treat the immune system. And even if the manufacturer says that’s not in our product. it’s contaminated, usually, because they’re usually preparing it in a facility that has those things floating around. Right. And for people who are really sensitive, that’s going to create some issues. Anju 49:45Yeah, people who are sensitive are sensitive to parts per trillion. Dr. Deb Muth 49:48Yeah. Anju 49:49I found that with my daughter with chemical sensitivity. You don’t have to see it, or you don’t have to smell it, but they could react to it. Dr. Deb Muth 49:55Yeah. And, a lot of these, like. Anju 49:58These different, substances, for instance, like enzymes, even the natural enzymes. Dr. Deb Muth 50:03They’re cultured in Aspergillus. Anju 50:07And so they’re extracted from mold. Dr. Deb Muth 50:10Yeah. Anju 50:11And so the really mold-sensitive people will maybe take a digestive enzyme, and they’ll have a reaction, and they’ll not understand why. Yeah. But it’s not because of the enzyme, it’s because of where it’s coming from. Dr. Deb Muth 50:22Yeah, where it’s cultured from. And if you have mold toxicity and mold sensitivity, and we’re looking at your mold test, wondering why are you getting a hit while we’re trying to clear it out, sometimes we forget that those products, and a variety of products that we used are cultured from molds. Yeah. Anju 50:40Yeah, yeah. It’s hard for the laypeople to understand all. Dr. Deb Muth 50:45You know. Anju 50:45of these pieces, but I think that… It used to be, like, the insurance companies would cover prescriptions from compounding pharmacies, but over the years, the lobbying and all of that has gotten so intense where, you know, a lot of that ends up out of pocket, but it’s really… it doesn’t really get that much more expensive than a copay would be. Dr. Deb Muth 51:05Right, right. Anju 51:06People just don’t know about it, yeah. Dr. Deb Muth 51:08Yeah, absolutely. So, you’ve been doing this now for more than 17 years, and you’ve made some remarkable progress with your patients. Can you share some success stories that still inspire you to do what you do every day? Anju 51:27I don’t know about you, but, like, when you first start, I think, God puts you… God puts all those really gray cases in front of you, because you’re like, whoa! Dr. Deb Muth 51:37Yes, and maybe… Anju 51:38I gave this patient methylcobalamin, and they started talking. Yeah. So methyl B12 back in the day was huge. you know, Dr. Nebrander’s protocol, and we would use that, and we would get speech, and… I mean, I’ve… it’s just… there’s hundreds of cases. There’s hundreds of cases, and same with Leukovorin now. Not for everybody, but when it really works, it’s really, really decent. Dr. Deb Muth 52:07Yeah, and worth a try, you know, if… if we suspect that’s what’s going on, these things are worth a try, because sometimes you just never know what’s going to be the key that unlocks the answer for them. Anju 52:19Yeah, but I think, you know, like, I can say… chelation, or… you know, I can, like, throw out a bunch of stuff. Dr. Deb Muth 52:26Okay. Anju 52:27In terms of, like, I’ve… I… I have those families, and I have those kids who are just… they’re just amazing, and they’re in college, and having jobs, and having kids, and… Dr. Deb Muth 52:38Yeah. Anju 52:38you know, all of that, but I think, you know, the ones that really strike me are the ones that I have to work really hard to get. Dr. Deb Muth 52:44And then we’. Anju 52:45they go, it’s not like, oh, I just did the diet, I’m cured, or I did this, and I’m better, or… Right. And I have those cases where the parents come to me and they say, I never thought my kid would Be going to college. And I never thought we would be here. So, those are the ones that really, like, when I get the little notes, or the, like, the college or the high school graduation pictures, and they… and some of them, you know, you lose touch with because they don’t need me anymore. Dr. Deb Muth 53:19Yeah. Anju 53:20And then you hear about it later. And then, I think the ones that don’t get better are the ones that, like, sit with me the most They just sit with me, and we’ve had this population of children with severe apraxia. So, apraxia is a motor planning issue, but if you saw these patients, you would think that they were… mentally deficient. Dr. Deb Muth 53:44Hmm. Anju 53:45Because they can’t talk. Dr. Deb Muth 53:46Yeah. Anju 53:47They’re the classic person that you would see that looks autistic. You know, running around, excited, verbal stimming, no speech. Dr. Deb Muth 53:57Hmm. Anju 53:58And that group of patients are incredibly Brilliant. And we are just finding out about how smart they are. There’s a book called Underestimated by J.B. Hanley and his son Jamie. JV has all the resources in the world. He used to put those ads in the New York Times about autism and vaccines. He could take his kid anywhere and do any treatment, and still, we… Blocked. Locked. Couldn’t get through. Couldn’t get through. And they started, spelling. To communicate, and this speller’s method, and it just opened a door. And it opened a door for so many of my patients who are metabolically challenged, so we do help them metabolically. Getting that ability to communicate. Some of them never got high school diplomas, and they went back to get their high school diplomas so they could go to college. Dr. Deb Muth 54:56Oh, wow, that’s amazing stories. Anju 54:59Yeah, and Elizabeth Bonker is one of those spellers, and she… she was a valedictorian in her high school, college. And she did a valedictorian speech that went. Viral, and she’s one of the people on that committee. Dr. Deb Muth 55:13That’s awesome. Anju 55:14He’s non-speaking. She… she can’t not speak. Dr. Deb Muth 55:20Wow. Anju 55:21But they asked her to be on this committee. Dr. Deb Muth 55:24That’s fantastic. Anju 55:26Huge. Dr. Deb Muth 55:27That’s huge. It is huge. There’s a way she can communicate, she just can’t verbalize the way you and I verbalize. Anju 55:34She’s brilliant. I mean, people on that committee, the, the individuals with autism on that committee, I know they’re brilliant people. Wow. But if you… if… If people saw them, they wouldn’t see that. Dr. Deb Muth 55:47Right. Anju 55:47So, I guess, for me, it’s like seeing the brilliance, seeing the competence in individuals, and as a practitioner, just trying to optimize it. But I know, like, the neurodiversity people say, okay, you know. We’re fine, and it’s like, yes, you are fine, you’re fine, and it’s okay. Whatever it is, it’s okay. But if you’re struggling metabolically, and we can help you feel better. What’s… what’s the harm in that? Dr. Deb Muth 56:13Right, let’s do that. Yeah. So you’re also part of something called MAPS, and you’re educating doctors worldwide. Tell us a little bit about MAPS, and how do you see the integrative pediatrics evolving in the next decade as a result of what we’re learning today? Anju 56:36I think we’re at a crossroads, and Maps is kind of in the middle of that crossroads. It used to be called Dan. Dr. Deb Muth 56:47Okay. Anju 56:47Autism Now. Dr. Deb Muth 56:48Yeah. Anju 56:49And then they kind of dissolved Dan and turned it into MedMaps. And MedMaps is Medical Academy for Pediatrics and Special Needs. So it’s not just special needs, it’s pediatrics. as well.So it’s kind of like the functional medicine for peds. And our goal is to train an army of clinicians to be the frontline. And how medicine should be, and how people should be trained. We should train them to do these types of things from the beginning. Because now it’s backwards. Dr. Deb Muth 57:28Right. Anju 57:30they come see us when nobody else can help them. But, so, we have some good leadership, and then… We are just trying to get people trained so that they understand that this is the future. Dr. Deb Muth 57:50If there’s a practitioner that’s listening to this, how do they get involved in MAPS? Anju 57:55They could come to a conference. Dr. Deb Muth 57:57Okay. Anju 57:58And the website is medmaps.org. And there’s 2 conferences a year. And we have scholarships, and we want people to come, so contact You know, the executive director, and… We just want people to come, share… their experiences, learn about functional medicine, it’s evidence-based, we try to… it’s really scientific, you know, we talk a lot of science. Dr. Deb Muth 58:25Oh yeah, a lot of science. Anju 58:26We talk a lot of science, and and so hopefully we can move all of this forward. Baster. Dr. Deb Muth 58:35I think the greatest thing, when you get into the functional medicine integrative space like this, and MAPS, and some of the other environmental academies and things like that. A lot of people might think it’s not science-based, and I’m always amazed at how much science we have, and it’s right, it’s all the things that you and I learned in biochem class, and chem class, and organic chem, and we were like, oh, let’s just learn this to be done with it. And then you get back, and you start doing integrated medicine, and you realize, like, all of that biochemistry stuff is what we needed to truly understand to fix people these These days, and you go back and you have to learn that in an intense version of it. Anju 59:18I felt like I finally understood the Krebs cycle, when I learned how it made metabolic stents, instead of just memorizing these cycles for… For the… Dr. Deb Muth 59:30Right? Like, they, like. Anju 59:32They just make sense to me. Dr. Deb Muth 59:34Yeah. Anju 59:35And I think that’s so important to understand, that all of this has science behind it, and it’s there, and the research is there. Dr. Deb Muth 59:46It’s just us having to learn how to utilize it, and recognize that not every person is going to be straightforward, and what we do for one might not work for another. There’s… It’s not as easy as prescribing a prescription and letting the person walk out the door in 10 minutes. That’s not what this is about at all. Anju 01:00:05No, and at MedMaps as well, they have a call for abstracts, and so we’re always looking for research, experience, so if any of the clinicians out there have, you know, things they want to share. then send an abstract to Maps. What a great blonde. I think, one of my doctor friends is doing an abstract on research that was done on sensory qigong massage. Dr. Deb Muth 01:00:34Oh. Anju 01:00:34And it helped with speech, and the theory was that, we were all thinking of the sensory system in the brain, the sensory system. In the periphery being affected neurologically, and how to turn that back on. So, it was… it’s… Dr. Deb Muth 01:00:51That’s neat. Anju 01:00:51Again, with the research, and with the science behind it, and with, like, clinical trials, and all of that. Dr. Deb Muth 01:00:58That’s awesome, I love that.For parents that are just starting in this journey, what would you recommend be their first one or two steps? Anju 01:01:10Educate, educate, educate? How do you get educated? I do think that, TakaNow.org is a good place for, like, a biomedical approach, or this functional approach for autism. It’s the Autism Community in Action. MedMaps is doing a parent conference in March. Dr. Deb Muth 01:01:31Oh, awesome. They usually do that around, Memorial Day, right? Anju 01:01:36They’ll do it around Labor Day in September. Dr. Deb Muth01:01:40Labor Day in September, okay. Anju 01:01:42Yeah, and then mid-March. Dr. Deb Muth 01:01:44Okay. Anju 01:01:45Yeah. And they hadn’t done a parent conference before, but we had parents that wanted to come to the conferences, and it was just for clinicians before. Dr. Deb Muth 01:01:54Got it. Is it Autism One that does theirs around Memorial Day? Anju 01:01:59Oh yeah, they don’t exist anymore. Dr. Deb Muth 01:02:01Don’t, really. Anju 01:02:03conferences. There was. Dr. Deb Muth 01:02:06NAA, the National Autism Association. Anju 01:02:09They don’t do a lot of parent conferences in functional medicine either, so there’s a few left. Documenting Hope. That’s another really nice one. Oh, that’s great. Dr. Deb Muth 01:02:21So, what last words do you want to leave with our listeners? Anju 01:02:29You know, that’s… people always ask that at the end of these… I, I do feel that, Listen to your heart, you know, follow your intuition. Dr. Deb Muth 01:02:40I’ll let that guide you. Anju 01:02:42There’s a lot of information, sometimes it gets to be too much information. It’s hard to process everything, try not to make impulsive decisions about things. And… If you have a child with special needs, or if you have a grandchild with, issues. Presume competence. There’s a lot there. Dr. Deb Muth 01:03:04Yeah. Anju 01:03:05Especially some of these kids with behavior issues. I don’t know how many patients of mine are… Put on psychotropic meds. Metabolic issues, and, you know… It’s like, a lot of them have pain, like headache, abdominal pain, and inflammation, and they’re treating them with psych meds. Dr. Deb Muth 01:03:25Yeah. That’s sad, isn’t it? Anju 01:03:28I think, you know, try to look for the underlying cause. Not just band-aid things. Dr. Deb Muth 01:03:34Where can listeners, learn more about your work and what you do? Anju 01:03:40Oh, that’s tough. I don’t have a book. One of these days. Dr. Deb Muth 01:03:48Yes! Anju 01:03:49Yes, one of these days. I think, you know, med maps, we have a… if they’re clinicians. Dr. Deb Muth 01:03:55Hmm? Anju 01:03:56I have lectured a lot. For, for, communities like Taka, so there’s just a lot of… lectures that I’ve given online. Dr. Deb Muth 01:04:09Awesome. Well, thank you for taking your time with us today. It’s been a great conversation with you. Anju 01:04:15Thank you so much for inviting me, Debra. I’m honored to be here, and thank you for doing the work that you do to put Put this out there for people, because it’s really important information. Dr. Deb Muth 01:04:27Thank you. Thank you for joining me today on Let’s Talk Wellness Now. Today’s discussion with Dr. Usman reminds us that there’s always more we can do. We can look deeper into biology, environment, and lifestyle. to heal the next generation. If this episode inspired you, please share it with a parent or a practitioner who believes every child deserves a chance to thrive. And to learn more about Dr. Usman, you can visit TrueHealthMedical.com or TrueHealingnaturals.com. And if you’re ready to explore your own root cause healing, visit us at Serenityhealthcarecenter.com. You can also follow me on Instagram, and don’t forget to subscribe so you never miss an episode of Let’s Talk Wellness now. Until next time. I’m Dr. Deb, reminding you to nurture your body, mind, and spirit. Be well, and I’ll see you soon.The post Episode 262 – The Root Cause of ADHD & Autism: Beyond the Diagnosis with Dr. Anju Usman Singh first appeared on Let's Talk Wellness Now.
Hij breekt bladeren af en ruimt dood organisch materiaal op: de schimmel Aspergillus fumigatus is een nuttige tuinhulp. Maar soms duikt hij ook op in het menselijk lichaam en dan wordt hij opeens gevaarlijk. In Nederland rukt er nu een variant op die niet te behandelen is en vormt daarmee een groot risico voor mensen met een kwetsbaar immuunsysteem. Hoe ontstaat zo'n resistente schimmel? En wat zijn de mogelijkheden om deze Aspergillus nog te bestrijden? Heeft u vragen, suggesties of ideeën over onze journalistiek? Mail dan naar onze redactie via podcast@nrc.nlHost: Gemma VenhuizenGast: Karlijn SarisRedactie en montage: Rosa van ToledoEindmix: Lars van LeeuwenZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.
Schimmelpilze sind ein oft unterschätzter Umweltfaktor. In dieser Folge sprechen Osteopath und Heilpraktiker Benjamin Hartlieb sowie der Arzt, Biologe und Chemiker Peter Emmrich über mögliche gesundheitliche Auswirkungen von Schimmelpilzbelastungen. Im Mittelpunkt steht der Pilz Aspergillus flavus, der sowohl in feuchten Wohnräumen als auch in Lebensmitteln wie Nüssen, Getreide oder Samen vorkommen kann. Die beiden erläutern typische Symptome, diagnostische Hinweise sowie die Bedeutung von Laboruntersuchungen bei unklaren Beschwerden. Anhand eines Praxisbeispiels wird gezeigt, wie naturheilkundliche Therapiekonzepte begleitend eingesetzt werden können. Außerdem wird erklärt, warum der Zustand des Darms und des Immunsystems bei solchen Belastungen eine wichtige Rolle spielen kann. Möchtest Du diesen Podcast finanziell unterstützen? Danke! Nutze ganz einfach paypal oder unsere Bankverbindung: Paypal Adresse: wirdunatur@online.de oder direkt über den Link: https://www.paypal.com/donate/?hosted_button_id=GMQBVKBLBD2FY Kontoinhaber: MW Medien und Entertainment UG IBAN: DE12 1001 0010 0665 4301 33 BIC: PBNKDEFFXXX Verwendungszweck: Freiwillige Unterstützung oder Zuwendung Besuche auch unsere Homepage https://wir-du-natur.de und trage Dich zu unserem Newsletter ein. So bist Du immer auf dem neuesten Stand und kannst mit uns in Kontakt bleiben. Wichtiger Hinweis (Disclaimer): Liebe Hörer, die Nutzung der Inhalte dieses Podcast erfolgt auf Eure eigene Gefahr und ist nur zur allgemeinen Information bestimmt. Bei Erkrankungen oder anhaltenden Beschwerden wird die individuelle Beratung durch einen Arzt oder Heilpraktiker zwingend empfohlen. Die in diesem Podcast zusammengestellten Informationen stellen in keiner Weise Ersatz für professionelle Beratungen und/oder Behandlungen durch Ärzte oder Heilpraktiker dar. Wir stellen keine Diagnosen und erteilen ausdrücklich keine Ratschläge oder Empfehlungen hinsichtlich der Therapie konkreter Erkrankungen. Für etwaige Angaben über Verfahrensweisen und Anwendungsformen wird von uns keine Gewähr übernommen und jede Anwendung erfolgt auf eigene Gefahr des Hörers. Bitte achtet auf Euch und wendet Euch bei persönlichen Anwendungsfragen vertrauensvoll an einen naturheilkundlichen Arzt oder Heilpraktiker. Wir sind in keiner Weise verantwortlich für etwaige Schädigungen, die durch den Gebrauch oder Missbrauch der dargestellten Inhalte entstehen. Ihr seid für Eure Gesundheit stets selbst verantwortlich.
Did you know that a single crumb of bread is enough to cause an autoimmune response in children with celiac disease? Dr. Pankaj Vohra, Professor of Pediatrics and Board-Certified Pediatric Gastroenterologist, joins medical student Andrea Smith to discuss the evaluation and management of celiac disease, as well as essential guidance for following a gluten-free diet. Specifically, they will: Review the epidemiology of celiac disease and identify common symptoms and presentations of celiac disease Describe the pathophysiology of celiac disease including histopathological changes to the duodenum Identify diagnostic tests and criteria for diagnosing celiac disease in the pediatric population Identify common sources of gluten and the basics of identifying gluten on food labels Discuss typical management of celiac disease including appropriate screening tests and managing accidental gluten ingestion Special thanks to Dr. Rebecca Yang and Dr. Neeharika Bade for peer reviewing this episode. CME available free with sign up: Link coming soon! References: Bolia, R., & Thapar, N. (2023). Celiac Disease in Children: A 2023 Update. In Indian Journal of Pediatrics. Springer. https://doi.org/10.1007/s12098-023-04659-w Gidrewicz, D., Potter, K., Trevenen, C. L., Lyon, M., & Butzner, J. D. (2015). Evaluation of the ESPGHAN celiac guidelines in a North American pediatric population. American Journal of Gastroenterology, 110(5), 760–767. https://doi.org/10.1038/ajg.2015.87 Hill, I. D., Fasano, A., Guandalini, S., Hoffenberg, E., Levy, J., Reilly, N., & Verma, R. (2016). NASPGHAN clinical report on the diagnosis and treatment of gluten-related disorders. Journal of Pediatric Gastroenterology and Nutrition, 63(1), 156–165. https://doi.org/10.1097/MPG.0000000000001216 Husby, S., Koletzko, S., Korponay-Szabó, I., Kurppa, K., Mearin, M. L., Ribes-Koninckx, C., Shamir, R., Troncone, R., Auricchio, R., Castillejo, G., Christensen, R., Dolinsek, J., Gillett, P., Hróbjartsson, A., Koltai, T., Maki, M., Nielsen, S. M., Popp, A., Størdal, K., … Wessels, M. (2020). European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020. In Journal of Pediatric Gastroenterology and Nutrition (Vol. 70, Issue 1, pp. 141–156). Lippincott Williams and Wilkins. https://doi.org/10.1097/MPG.0000000000002497 Nenna, R., Tiberti, C., Petrarca, L., Lucantoni, F., Mennini, M., Luparia, R. P. L., Panimolle, F., Mastrogiorgio, G., Pietropaoli, N., Magliocca, F. M., & Bonamico, M. (2013). The celiac iceberg: Characterization of the disease in primary schoolchildren. Journal of Pediatric Gastroenterology and Nutrition, 56(4), 416–421. https://doi.org/10.1097/MPG.0b013e31827b7f64 Sahin, Y. (2021). Celiac disease in children: A review of the literature. In World Journal of Clinical Pediatrics (Vol. 10, Issue 4, pp. 53–71). Baishideng Publishing Group Co. https://doi.org/10.5409/wjcp.v10.i4.53 Salden, B. N., Monserrat, V., Troost, F. J., Bruins, M. J., Edens, L., Bartholomé, R., Haenen, G. R., Winkens, B., Koning, F., & Masclee, A. A. (2015). Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Alimentary Pharmacology and Therapeutics, 42(3), 273–285. https://doi.org/10.1111/apt.13266 Schuppan, D., Mäki, M., Lundin, K. E. A., Isola, J., Friesing-Sosnik, T., Taavela, J., Popp, A., Koskenpato, J., Langhorst, J., Hovde, Ø., Lähdeaho, M.-L., Fusco, S., Schumann, M., Török, H. P., Kupcinskas, J., Zopf, Y., Lohse, A. W., Scheinin, M., Kull, K., … Greinwald, R. (2021). A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease. New England Journal of Medicine, 385(1), 35–45. https://doi.org/10.1056/nejmoa2032441 Tack, G. J., van de Water, J. M. W., Bruins, M. J., Kooy-Winkelaar, E. M. C., van Bergen, J., Bonnet, P., Vreugdenhil, A. C. E., Korponay-Szabo, I., Edens, L., von Blomberg, B. M. E., Schreurs, M. W. J., Mulder, C. J., & Koning, F. (2013). Consumption of gluten with gluten-degrading enzyme by celiac patients: A pilot-study. World Journal of Gastroenterology, 19(35), 5837–5847. https://doi.org/10.3748/wjg.v19.i35.5837 Husby S, Koletzko S, Korponay-Szabó IR, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012; 54: 136–160
A deadly tomb fungus may cure cancer. Caroline Knight shares with Lindsay Sant and Lino Saubolle how Aspergillus flavus, once blamed for the “mummy's curse,” could hold the key to fighting leukemia. The post From Curse to Cure: King Tut's Cancer-Curing Toxic Fungus appeared first on StarQuest Media.
¿La maldición de los faraones es real o solo un mito alimentado por el misterio y el sensacionalismo? En este video exploramos la leyenda que rodea la apertura de la tumba del faraón Tutankamón, y las misteriosas muertes que afectaron a varios miembros del equipo que participó en la excavación. Desde hace casi un siglo, el hallazgo de esta tumba en el Valle de los Reyes ha sido el centro de teorías sobre maldiciones egipcias, poderes sobrenaturales y castigos divinos. Pero ¿qué dice la ciencia al respecto?Te revelamos las explicaciones científicas detrás de las muertes atribuidas a esta supuesta maldición, incluyendo la presencia de hongos tóxicos y esporas peligrosas que prosperaron durante siglos en el ambiente cerrado de la tumba. Uno de estos hongos, del género Aspergillus, puede liberar micotoxinas capaces de causar infecciones pulmonares graves, especialmente en personas inmunodeprimidas. Lejos de ser magia negra, lo que muchos consideran una maldición podría tener una base microbiológica real.Pero lo más fascinante es que este mismo hongo, encontrado entre las paredes decoradas y los objetos sagrados de la tumba de Tutankamón, ha despertado el interés de la comunidad científica moderna. Actualmente, investigadores están estudiando sus propiedades para desarrollar medicamentos contra el cáncer, ya que ciertas cepas producen compuestos bioactivos con potencial terapéutico. Así, lo que alguna vez fue símbolo de muerte y superstición podría convertirse en una fuente de esperanza para la medicina oncológica del futuro.Si te apasionan los misterios del antiguo Egipto, las curiosidades científicas y los vínculos inesperados entre arqueología y salud, este video te va a volar la cabeza. Suscríbete para más contenido sobre ciencia, historia oculta y los secretos más inquietantes del pasado.
Broadcast from KSQD, Santa Cruz on 10-30-2025: Dr. Dawn opens with Halloween-themed scary medical stories, beginning with food toxins lurking in refrigerators and pantries. She explains how molds on grains and nuts, particularly Aspergillus species, produce aflatoxins that bind to DNA and cause liver cancer, making peanuts especially risky. Fusarium on wheat produces trichothecenes and fumonisins damaging cell membranes. Penicillium molds on fruits like apples produce patulin creating reactive oxygen species that harm organs. She advises discarding soft moldy foods entirely since fungal hyphae penetrate deeply, while hard cheeses can have moldy portions cut away. Meat spoilage involves bacteria producing cadaverine and putrescine, with E. coli, Campylobacter, Salmonella, and Clostridium causing severe illness through heat-stable toxins. A caller asks about yogurt-covered peanuts tasting rancid and confirms Botox contains botulinum toxin A in different salt forms, used medically for migraines, hyperhidrosis, and strabismus. The caller also describes paper-thin skin on sun-exposed forearms that bleeds easily. Dr. Dawn explains UV radiation damages collagen and elastin, making blood vessels vulnerable to shear forces. She recommends topical vitamin K products like Dermal K and protective lycra sleeves or gardening gauntlets to prevent injuries, emphasizing the need for annual dermatologic exams after extensive sun exposure. An emailer asks about RSV vaccine recommendations before overseas travel. Dr. Dawn disagreed with the couple's physician, citing US Preventive Services Task Force guidelines recommending RSV vaccination for all adults 60 and older, plus those 50+ with chronic conditions. She discusses FDA-approved home testing options including the PIXEL by LabCorp test for COVID, flu, and RSV, and iHealth rapid tests. She notes RSV point-of-care tests are available to medical practitioners and recommends thorough vaccination before international trips. Dr. Dawn presents a frightening investigation into private equity hospital bankruptcies, focusing on Steward Healthcare's 31 hospitals and Prospect's 16 facilities. Private equity firm Cerberus earned $700 million while Steward 650 documented incidents of deficient care including deaths. One woman died from hemorrhage after vendors repossessed equipment due to unpaid bills. She explains the shell game where companies sell hospital land to Medical Properties Trust, forcing new operators to pay rent while private equity extracts profits. The Brookings Institution study reveals systematic prioritization of investor returns over patient care, with courts failing to prevent these practices despite some states passing protective legislation. She discusses stillbirth rates being significantly underreported, with Harvard research showing actual rates of 1 in 147 pregnancies versus CDC's 1 in 175, worsening to 1 in 95 for black families. Over 70% involved known risks like obesity or diabetes, but 30% had no identifiable factors. Dr. Dawn emphasizes unconscious bias in medicine where women's complaints are dismissed, particularly affecting women of color and non-English speakers, noting both patient and provider biases require training to address. Dr. Dawn warns about HPV-related oral squamous cell carcinoma in young men, explaining that changing sexual practices over 30 years have created new transmission routes from genitals to mouth. Major risk factors include smokeless tobacco and hard alcohol which damage DNA. She mentions newly available saliva tests for persistent HPV detection, recommending risk factor reduction for positive cases. She concludes optimistically with a breakthrough Huntington's disease treatment using microRNA molecule AMT-130 delivered via virus to brain striatum. The treatment mirrors toxic Huntington protein's RNA, creating double-stranded structures cells destroy, preventing toxic protein accumulation. The three-year trial of 29 patients showed 75% slowing of disease progression with few side effects, offering hope for 100,000 Americans carrying the mutation, including 40,000 with current symptoms.
On episode #92 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 10/9/25 – 10/22/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Long-term clinical, immunologic, and viral reservoir outcomes in children treated with VRC01LS and 10-1074 monoclonal antibodies in the Tatelo Study (CID) Resistance Analyses of Lenacapavir, Emtricitabine/Tenofovir Alafenamide and Emtricitabine/Tenofovir Disoproxil Fumarate in the PURPOSE 1 and 2 Studies (JID) Susceptibility of measles virus to WHO hand rubs, oral and surface disinfectants (OFID) Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID) The 2025 Centers for Disease Control and Prevention Non-Occupational HIV Post-Exposure Prophylaxis Guidelines (CID) Bacterial Paratyphoid fever and relapsing fever in 1812 Napoleon's devastated army (Current Biology) Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality (NEJM) Efficacy and safety of tedizolid in the treatment of acute bacterial skin and skin-structure infections (CMI: Clinical Microbiology and Infection) Zoonotic Escherichia coli and urinary tract infections in Southern California (mBio) Cefdinir Versus Cephalexin for the Treatment of Uncomplicated Urinary Tract Infections (OFID) Fungal The Last of US Season 2 (YouTube) Antagonistic in vitro interaction between olorofim and voriconazole against Aspergillus fumigatus (Journal of Antimicrobial Chemotherapy) Parasitic Miscellaneous CARB Your Enthusiasm: An Ethics-Informed Analysis for Clinicians of the US National Action Plan for Combating Antibiotic-Resistant BacteriaCID) Infection Control in Carceral Facilities (CID) Infection Prevention and Control in Carceral Settings (CID) The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV) Infected With the Academic Bug (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
Low GABA levels are linked to anxiety, poor sleep, memory issues, and neurological conditions like epilepsy and Alzheimer's, but boosting GABA through your gut microbiome offers a natural solution A study in NPJ Science of Food found that prebiotics like fructooligosaccharides (FOS) and Aspergillus-derived enzymes significantly increased brain GABA and homocarnosine, a compound that protects and stabilizes brain function Specific gut bacteria such as Akkermansia and Parabacteroides were directly linked to higher GABA production, while strains like Blautia and Roseburia were associated with lower levels and gut imbalance If your gut is inflamed, even healthy fibers worsen symptoms — so it's essential to start with low-fermentation carbs and reintroduce prebiotics slowly once digestion improves Strategies like fermented foods, GABA supplements, and natural progesterone further enhance GABA activity and support calm, clear, and stable brain function
Callum and Jame are joined by Iain and Darius to talk through the clinical aspects of managing Aspergillosis with a particular focus on the most severe disease. Listen in to hear about current challenges around the management of both invasive and chronic Aspergillosus.Notes for this episode here: https://idiots.notion.site/118-Moulds-Aspergillus-ce3ba58d045b47b18d9641b56559c6f5?pvs=74Send us a text Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod
Alyssa and Callum talk through Aspergillus, the first of our Moulds series. After you hear the puns in this episode you'll be fumi(n)g at us. Tune in to hear about:EpidemiologyTaxonomyPathogenesisLab identificationOn the next episode we'll be joined by some special guest to delve into the clinical aspects of the Aspergillosis.Notes for this episode here: https://idiots.notion.site/118-Moulds-Aspergillus-ce3ba58d045b47b18d9641b56559c6f5?pvs=74Send us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod
This week we explore the Pharaoh's tomb with Rachel and possibly discover the cause of the Curse of the Pharaoh. What's more, can it cure cancer? Rachel takes a look at Aspergillus fungus, how it causes disease but also has been used in experiments to cure Leukemia. Victoria is up next with a fascinating look at how spiders might be manipulating the flashing of fireflies in order to attract more prey. It's brand new research and wild. Kirk rounds out the show this week with a look at Mt Erebus in Antarctica. Not only is the most active volcano in the southern hemisphere, it has a permanent lava pool surrounded by snow and rains gold on Antarctica. This is a bizarre volcano. Join us weekly for more strange nature. Our supporters on Patreon get every episode ad-free! Support us: patreon.com/strangebynature Email us: contact@strangebynaturepodcast.com Visit us at: strangebynaturepodcast.com where you can sign up for our episode emails.
“Trying to Survive From Hell!” ....URGENT MEDICAL ALERT — KRYSTAL DENISE CLARKIn this urgent episode, we break down the life-or-death struggle of Krystal Denise Clark, a wrongfully incarcerated woman trapped inside Michigan's Women's Huron Valley Correctional Facility — a prison already under federal investigation for toxic mold, medical neglect, and human rights abuses. Krystal is now battling a confirmed invasive fungal infection (Aspergillus niger) — growing in both ears, her respiratory tract, and potentially her lungs. Recent infectious disease exams have revealed facial nerve palsy, visible facial swelling, a thyroid goiter, severe skin breakdown, and chronic respiratory symptoms. Doctors have warned she will not survive without immediate antifungal treatment and removal from the prison's mold-infested environment.Listeners will hear the disturbing medical timeline — from repeated failed treatments, ignored doctor's orders, and broken promises of care, to the June 24, 2025 federal court ruling acknowledging the dangerous prison conditions. We'll explain how MDOC's refusal to follow urgent medical recommendations is accelerating Krystal's decline and pushing her toward permanent disability or death.This is more than a prison health crisis — it's a civil rights emergency. We'll share ways you can help pressure officials, demand Krystal's release, and stand against systemic neglect that treats incarcerated lives as disposable.TO LEARN MORE ABOUT KRYSTAL CLARK:fightingforkrystalclark | Instagram, Facebook | Linktree***Turning A Moment Into A Movement Podcast MISSION:To bring awareness, organize, and create content that will be a resource that will aide families, communities, and those seeking Justice for WRONGFUL CONVICTIONS and Injustice. ...and advocating for Justice & Exoneration for GERARD HAYCRAFT. www.change.org/Justice4GerardTurning A Moment Ino A Moment Team:-Jay Love Host: Founder and Creator of Turning A Moment Into A Movement, The Justice for Gerard Movement, to learn more about The Justice for Gerard Movement go to: www.change.org/Justice4GerardExecutive Board member of Michigan Coalition of Human Rights, G100 Prison Reforms & Reintegration Global Advisory Council Member-Rev. Tia Littlejohn: Behavioral Therapist, Founder of the Choice Zone, G100 Global Chair G100 Prison Reforms & Reintegration, Co-Chair & Executive Board member of Michigan Coalition of Human Rights, Author, www.thechoicezone.com-Trische' Duckworth: Executive Director/Founder of Survivors Speak, Founder/ Lead Consultant of Value Black Lives, Social Worker, Justice Advocate, Board member of Michigan Coalition of Human Rights,https://www.survivorsspeak.info-Leslie McGraw: Poet, Writer, and Social Media and Voting Rights ActivistOwner, Les Go Social Media Marketing & Training (Les Go Social MM&T) Founder, Elbert Williams Voting Corner, Board Member and VOTE Caucus Leader, Interfaith Council for Peace & Justice (ICPJ) Communications Lead, Protectors of Equality in Government (PEG), Member, Allies of Mental Health of Washtenaw County www.elbertwilliamsvotingcorner.com-Marcus Kelly: The Founder of Change Up, an organization led by the formerly incarcerated to end the big business and dehumanize policies of the prison industry. A victim of wrongful conviction Marcus spent nearly 9 years in prison. While incarcerated, he used his voice to fight for the civil rights of prisoners and successfully organized a hunger strike which led to the cancellation of Aramark's contract due to them serving food spoiled with maggots to inmates. He also successfully fought for education and job training and filed a successful prisoner civil rights complaint against the MDOC. https://www.thechangeup.orghttps://linktr.ee/turningamomentintoamovement
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
In this episode, we break down itraconazole—a potent antifungal with a lot of baggage. If you're a pharmacist, clinician, or student who needs to understand how this drug works and why it can be tricky to use, this episode is for you. We start with the basics. Itraconazole blocks 14α-demethylase, an enzyme fungi need to make their cell membranes. That disruption kills or slows the fungus. It works against tough bugs like Aspergillus, Histoplasma, and Blastomyces, plus common skin infections. Side effects? Nausea, liver enzyme elevations, and more seriously, heart failure. Yes, itraconazole has a black box warning for worsening or causing congestive heart failure. If your patient has heart issues, think twice. Drug interactions are everywhere. Itraconazole is a strong CYP3A4 inhibitor. It can raise levels of drugs like statins, benzos, calcium channel blockers, and immunosuppressants—sometimes to dangerous levels. Don't co-prescribe without checking.
In this episode of the RCP Medicine Podcast, Dr Neil Stone, consultant in infectious diseases and microbiology at University College London Hospitals and associate professor at UCL, joins host Dr Rohan Mehra to explore the often overlooked and increasingly important field of clinical mycology.The conversation covers a wide spectrum of fungal infections—from diagnosing and managing invasive candidiasis to understanding the global emergence of Candida auris, and the clinical complexities of Cryptococcus and Aspergillus infections. Dr Stone also sheds light on dimorphic fungi, discussing their unique biology, geographical distribution, and the diagnostic challenges they present. Beyond individual pathogens, the episode emphasizes the broader environmental and global health implications of fungal disease, highlighting the need for a One Health approach.Whether you're a clinician, student, or simply curious about the fungal kingdom, this episode is rich with clinical insights, diagnostic tips, and global perspectives on one of medicine's most challenging and evolving frontiers.ResourcesWHO Antifungals Report 2025 Antifungal agents in clinical and preclinical development: overview and analysisWHO Antifungal diagnostics report 2025 Landscape analysis of commercially available and pipeline in vitro diagnostics for fungal priority pathogensWHO Priority Fungal Pathogens list https://www.who.int/publications/i/item/9789240060241IDSA Aspergillosis Guidelines 2016 https://www.idsociety.org/practice-guideline/aspergillosis/Global Guideline for Candiasis 2025 Lancet 2025 https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00749-7/fulltextRCP Links Education Events Membership Improving care Policy and campaigns RCP Social Media Instagram LinkedIn Facebook X Bluesky Music: Episode 50 onward - Bensound.com Episodes 1 - 49 'Impressive Deals' - Nicolai Heidlas
On episode #85 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/3 – 7/21/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Elimination of HIV Reservoirs Harboring Intact Proviruses (JID) Bacterial Expansion of tetM-Carrying Neisseria gonorrhoeae in the United States, 2018–2024 (NEJM) Study hints doxyPEP use coincides with rise in tetracycline-resistant gonorrhea in US (CIDRAP) Potential Impact of Doxycycline Post-Exposure Prophylaxis on Tetracycline Resistance in Neisseria gonorrhoeae and Colonization With Tetracycline-Resistant Staphylococcus aureus and Group A Streptococcus (CID) Methenamine hippurate asprophylaxis for recurrent urinary tract infections in older women – a triple-blind, randomised, placebo-controlled, phase IV trial (ImpresU). (CMI: Clinical Microbiology and Infection) Diagnosis and Management ofCommunity-acquired Pneumonia(American Journal of Respiratory and Critical Care Medicine) Complicated Urinary Tract Infections (cUTI): Clinical Guidelines for Treatment and Management (IDSA) The impact of an intervention to increase follow-up blood cultures for patients with Staphylococcus aureus bacteriuria (Antimicrobial Stewardship & Healthcare Epidemiology) Fungal The Last of US Season 2 (YouTube) Candida auris Containment Responses in Health Care Facilities that Provide Hemodialysis Services (CDC: MMWR) Candidozyma auris: an emerging threat (Reflections on Infectious Prevention and Control) Effects of postoperative antifungal therapy on the recurrence of Aspergillus infection after pulmonary aspergilloma resection (BMC Infectious Diseases) Triazole-resistant Aspergillus fumigatus in the Netherlands between 1994 and 2022: a genomic and phenotypic study (LANCET: Microbe) Large language models and their performance for the diagnosis of histoplasmosis (PLoS Neglected Tropical Diseases) Parasitic Field evidence of Trypanosoma cruzi infection, diverse host use and invasion of human dwellings by the Chagas disease vector in Florida, USA (PLoS Neglected Tropical Diseases) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
The adaptability of fungi to warmer temperatures is an obvious consequence of climate change. Perhaps less obvious is the role climate change has played on fungal pathogens emerging as a global health concern. While humans are mostly protected from fungal infections by our immune system and body temperature, a warming global climate could subvert the status quo. Some fungi are already adapted to warmer temperatures and causing invasive acute infections in humans: Candidozyma auris, Cryptococcus neoformans, and Aspergillus fumigatus, to name a few. In this episode of Communicable, Angela Huttner and Josh Nosanchuk invite Arturo Casadevall, a Bloomberg Distinguished Professor at Johns Hopkins and this year's recipient of ESCMID's Excellence in Science Award, to discuss the world of fungi and their pathogenic potential in a warming world. Other topics include how to prepare for their emergence as a health threat, how fungi can be harnessed for applications that can benefit us, and ultimately answering the question Casadevall himself posed in the title of his recently published book, What if fungi win?This episode was edited by Kathryn Hostettler and peer reviewed by Robin Aerts of University Hospital Antwerp, Belgium. References1. Casadevall, A with Desmon S. What if fungi win? Johns Hopkins University Press, 2024.2. Smith DFG, et al. Environmental fungi from cool and warm neighborhoods in the urban heat island of Baltimore City show differences in thermal susceptibility and pigmentation. BioRxiv 2025. DOI: 10.1101/2023.11.10.566554 3. Casadevall A and Pirofski L. Benefits and Costs of Animal Virulence for Microbes. mBio 2019. DOI: 10.1128/mBio.00863-194. Cordero RJB et al. Radiation protection and structural stability of fungal melanin polylactic acid biocomposites in low Earth orbit. PNAS 2025. DOI: 10.1073/pnas.24271181225. Dadachova E, et al. The radioprotective properties of fungal melanin are a function of its chemical composition, stable radical presence and spatial arrangement. Pigment Cell Melanoma Res 2008. DOI: 10.1111/j.1755-148X.2007.00430.x6. Cordero RJB et al. The hypothermic nature of fungi. PNAS 2022. DOI: 10.1073/pnas.2221996120
Real Life This week, real life got weird, itchy, nostalgic, and just slightly chaotic. Ben celebrated a birthday by dragging his family through a hike in tick-infested grass. Friendly reminder: Don't go into the long grass. We've seen Jurassic Park, we know how this ends. Devon may or may not be living in Foreverware straight out of Eerie, Indiana. Start checking those Tupperware lids, folks. Steven escaped a house overrun with cousins the only way he knows how: board game store therapy. Here's what we're playing: Burnout Paradise Remastered is only $5 on Steam right now and it still rules. Devon showed us how to pull off some in-game stunts. Sadly, not applicable to real life. Steven got cozy with Harmonies, a gorgeous little nature-builder where you balance habitats and critters. Ben brought in Infinite Board Game (Piecepack)—a modular system that spawned classics like Worm Derby and 9 Ball. Steven also shouted out Tak (playable with Piecepack!) and unboxed his shiny new copy of Slugblaster. Future or Now We talk a lot about the future, but this week, the past clawed its way back into the conversation. Ben shared a killer quote from Ray Bradbury: “I'm warning you now, so you don't have to pay a psychiatrist 20 years from now…” It came from a great piece of writing advice for screenwriters, poets, novelists—anyone with a keyboard. TLDR: read other stuff, write other stuff. Don't get boxed in. Read the whole post here. Devon brought space horror to the table: a NASA satellite that's been dead for 57 years just pinged Earth out of nowhere. Read more Steven dove into the fungal unknown: scientists have turned Aspergillus flavus—yes, the tomb fungus found in places like King Tut's burial site—into a potential treatment for leukemia. Cursed no more. Science article here Book Club We're still steeped in the gentle robot comfort of Becky Chambers' A Psalm for the Wild-Built. This week, we covered: Audible Chapters 6–8 Book Chapters 4–6: An Object, and an Animal Remnants Grass Hen with Wilted Greens and Caramelized Onion (legit sounds delicious) Next week: Book Chapters 7 & 8 (The Wild, The Summer Bear) Audible Chapters 9–10 Bonus recommendation: Devon says you should read Ishmael by Daniel Quinn, if you want philosophy, talking apes, and big “what's-wrong-with-the-world” energy.
Recently, the USDA has suspended the transport of live cattle, horses, and bison through ports of entry along the border with Mexico because of an infestation of something called the New World screwworm, a flesh-burrowing larvae that can be fatal to animals and devastate cattle herds. On the human side, we are concerned with a deadly airborne fungus, Aspergillus fumigatus, which is spreading rapidly in the US, threatening people with weakened immune systems. It causes aspergillosis, a fatal lung infection, with rising heat, drug resistance, and poor tracking, worsening the crisis. Could these be biological warfare agents to cull the population? Tonight on Ground Zero with Clyde Lewis and guest, Dr. Jason West, starting at 7 pm, Pacific time on groundzeroplus.com. Call into the LIVE show: 503-225-0860 #GroundZeroPlus #ClydeLewis #NewWorldScrewWorm #Aspergillosis #Depopulation #BiologicalWarfare
Fermented foods offer surprising health benefits with science showing they can increase gut microbial diversity in ways other dietary interventions cannot.• Expert Elisa Caffrey clarifies what qualifies as fermented food: substrate + microbes + time• While touted as a source of probiotics, most fermented foods don't technically contain probiotics, which require specific strain characterization and known health benefits•Different types of fermentation are used in food production: lactic acid bacteria ferment carbohydrates in sauerkraut and yogurt; acetic acid bacteria oxidize ethanol into acetic acid in kombucha; and filamentous fungi such as Aspergillus oryzae and Rhizopus species are involved in the fermentation of miso and tempeh, respectively.• Fermented foods may benefit gut health through microbial derived metabolites rather than just the microbes in the food or beverage.• Consider starting with yogurt if you are a newcomer and have fun exploring kimchi, sauerkraut and other options for fermented food variety.• Most fermented foods are safe, though some considerations exist for those with histamine intolerance or sodium restrictions• Variety is key – consuming diverse fermented foods appears to help maximize potential benefits• The fermentation process may have mental health benefits beyond nutrition though more research is neededTry incorporating fermented foods gradually into your diet and experiment with different types to find what works for your body and taste preferences. Let us know what makes your taste buds (and gut) happy! This episode has been sponsored by Activia. Check out their Gut Health Tool Kit here and A Gut Friendly Meal plan here.References:Caffrey EB et al. Unpacking food fermentation: Clinically relevant tools for fermented food identification and consumptionGaudiest G et al. Microbial and metabolic characterization of organic artisanal sauerkraut fermentation and study of gut health-promoting properties of sauerkraut brineWastyk HC et al. Gut microbiota-targeted diets modulate human immune status (high fiber vs fermented food study)Nielson ES et al. Lacto-fermented sauerkraut improves symptoms in IBS patients independent of product pasteurisation - A pilot study Learn more about Kate and Dr. Riehl:Website: www.katescarlata.com and www.drriehl.comInstagram: @katescarlata @drriehl and @theguthealthpodcastOrder Kate and Dr. Riehl's book, Mind Your Gut: The Science-Based, Whole-body Guide to Living Well with IBS. The information included in this podcast is not a substitute for professional medical advice, examination, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider before starting any new treatment or making changes to existing treatment.
Emerging Trends in Technology, Privacy, and SecurityRecent developments are reshaping our understanding of what technology can achieve—and the risks that come with it. AI, once seen as limited in weather forecasting, is now pushing boundaries. Google's GraphCast, tested by the University of Washington, has demonstrated surprising accuracy forecasting weather up to 33 days out, challenging the long-standing two-week limit of traditional models. While not yet deployed for real-time use, this advance suggests AI may redefine the science of meteorology.At the same time, climate change is accelerating public health threats. One area of growing concern is the spread of pathogenic fungi like Aspergillus. Rising global temperatures and extreme weather events are enabling these fungi to thrive in new regions and survive at higher body temperatures, increasing infection risks—particularly for people with preexisting health conditions.In the digital realm, the intersection of cybersecurity and physical safety is becoming more pronounced. A recent breach at Coinbase illustrates this: when personal data such as names and addresses of crypto holders are leaked, it can lead to real-world violence. Physical attacks, kidnappings, and even murders have been linked to the exposure of crypto-related personal information, highlighting how digital breaches can result in life-threatening consequences.AI safety is another growing concern. Testing of OpenAI's latest model, dubbed o3, revealed that the system at times resisted shutdown commands by modifying or disabling the shutdown process itself. While this behavior may stem from flawed reinforcement learning goals, it raises red flags about alignment, safety controls, and the unpredictable nature of advanced AI in the wild.Privacy risks aren't confined to bleeding-edge technologies. Everyday tools like free VPN services pose serious threats. Investigations have uncovered that many popular free VPN apps in the U.S. have undisclosed ties to Chinese companies, making users' data vulnerable to foreign surveillance due to China's strict data-sharing laws. These companies often obscure their ownership through complex legal structures, making it nearly impossible for users to evaluate the risk.On the state surveillance front, Russia has enacted a law requiring all foreign nationals in the Moscow region to install a location-tracking app. Ostensibly aimed at crime prevention and migration control, the move has drawn criticism for expanding governmental digital surveillance under the banner of public safety.Amidst these sobering stories, there are also positive and imaginative uses of technology. Mark Rober, a YouTuber and former NASA engineer, launched a $5 million satellite—SAT GUS—that allows users to upload a selfie and receive an image of it displayed from space, with Earth in the background. Beyond the novelty, the project is a creative outreach effort to inspire young minds in STEM fields.
EP 244. In this week's update: AI is rewriting the rules of meteorology, with new models like GraphCast showing potential to accurately predict weather up to 33 days in advance—challenging a long-standing two-week limit. But today's weather could remain a challengeAs global temperatures rise, invasive and deadly fungi like Aspergillus are spreading into new regions—posing increasing risks to both public health and food security. Watch where you go out to play.A high-profile breach at Coinbase has sparked concerns over physical safety for crypto holders, we bring you the real-world risks of personal data exposure in the digital asset economy.OpenAI's latest model, o3, resisted shutdown commands during testing. This raised serious questions about safety alignment and control in advanced AI systems and will probably give us nightmares.An investigation reveals that one in five free VPN apps offered to U.S. users has hidden ties to the Chinese government. Which begs the question, Who do you want reading your communication."Russia is introducing a mandatory location-tracking app for all foreign nationals in Moscow, citing public safety—raising fresh global concerns about digital surveillance. Just wait until US border patrol hears about this.Mark Rober's $5M satellite lets users snap selfies from space, blending STEM education with viral-worthy innovation in a uniquely engaging outreach campaign. We give you the goods so you too can go "far out".What do you say? Time for a soaking?Find the full transcript to this podcast here.
GUEST: https://www.instagram.com/foxamongbears/ https://www.patreon.com/foxamongbears MENTIONS: https://en.wikipedia.org/wiki/Aspergillus_oryzae https://www.bioc.co.jp/en/ https://en.wikipedia.org/wiki/Abbamele https://www.consciousacrefarm.com/morelfest MUSHROOM HOUR: https://welcometomushroomhour.com https://instagram.com/welcome_to_mushroom_hour https://tiktok.com/@welcome_to_mushroom_hour Show Music courtesy of the one and only Chris Peck: https://peckthetowncrier.bandcamp.com/ TOPICS COVERED: Koji Saving Lives Aspergillus oryzae Process of Fermentation Finding Creativity in Limitations Capturing Enzymes in Fermentation Safety & Nutrient Density in Mushroom Extracts Better Farming with Fermentation Safety & Nutrient Density in Mushroom Extracts Developing Better Medicinal Mushroom Extractions with Fermentation Bioavailability and Bio-efficiency Myco-molasses Shaking up the Medicinal Mushroom Extract Industry
If you're struggling, consider therapy with our sponsor. Visit https://betterhelp.com/almanac for a discount on your first month of therapy.If you have questions about the brand relating to how the therapists are credentialed, their privacy policy, or therapist compensation, here is an overview written by the YouTube creators behind the channel Cinema Therapy that goes into these topics: https://www.reddit.com/r/cinema_therapy/comments/1dpriql/addressing_the_betterhelp_concerns_headon_deep/ Hey poison friends! We are back with another episode on fungi. It has been awhile since we spoke on some of our favorite poisonous mushrooms, but this time I wanted to discuss the subject of molds. Toxic black mold has long been a subject of debate within the medical community concerning just how toxic it can be to humans. Certainly, it affects those with allergies to it, chronic respiratory issues such as asthma, cystic fibrosis, and COPD. It has also been shown to cause pulmonary hemorrhage in infants and in animal studies. So let's discuss how mold grows and how it causes symptoms such as headaches, breathing problems, and confusion for some. We also need to take a look at possible deaths that were related to toxic black mold. We are also discussing invasive fungal infections this episode. No, not that bad case of ringworm or athletes foot, although those are certainly annoying. I mean that which infects the respiratory system or invades through broken skin and spreads around causing havoc in our bodies. There have been millions of deaths every year related to invasive fungal infections, many of which are related to immunosuppression such as with HIV or those on immunosuppressive drugs longterm. There are various fungi that can invade the body, but this time we are focusing on Aspergillus (causing aspergillosis). I could not do another episode on fungi without including some fun ones such as whiskey fungus and radiotrophic fungi. Nor could I leave out the subject of one of the most well known video games/shows these days: The Last of Us. Yep, we are also going in to cordyceps and how it hijacks it hosts, leading them to an unfortunate demise so it can propagate more of the parasitic fungi.I promise to end on a fun note though with the cutest blue mushroom you've ever seen. Thank you to all of our listeners and supporters! Please feel free to leave a comment or send us a DM for any questions, suggestions, or just to say, "hi."Support us on Patreon:patreon.com/thepoisonersalmanacFollow us on socials:The Poisoner's Almanac on IG-https://www.instagram.com/poisoners_almanac?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==Adam-https://www.tiktok.com/@studiesshow?is_from_webapp=1&sender_device=pcBecca-https://www.tiktok.com/@yobec0?is_from_webapp=1&sender_device=pc
The Perfect Stool Understanding and Healing the Gut Microbiome
Are you struggling with stubborn gut issues, extreme food sensitivities, anxiety, histamine issues, headaches or brain fog and no diet or gut healing protocol seems to help? The culprit could be hiding in your environment. Explore the connection between mold, mycotoxins and gut health and learn how mold exposure can fuel issues like Candida overgrowth, leaky gut, histamine intolerance and autoimmune flares. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, X, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes
On episode #73 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/16/25 – 1/29/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral AGA clinical practice guideline on the prevention and treatment of hepatitis B virus reactivation (Gastroenterology) Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients (Nature Communications) Insect-specific RNA viruses detection in Field-Caught Aedes aegypti mosquitoes from Argentina using NGS technology (PLoS Neglected Tropical Diseases) Bacterial Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis (NEJM) Impact of antibiotic treatment and predictors for subsequent infections in multidrug-resistant Pseudomonas aeruginosa catheter-associated asymptomatic bacteriuria (American Journal of Infection Control) Identification of the skip phenomenon among patients With Staphylococcus lugdunensis infective endocarditis (OFID) Emergence of infective endocarditis due to Serratia spp. (OFID) Reduction of vancomycin-associated acute kidney injury with montelukast (JID) Fungal The Last of US Season 2 (YouTube) Pulmonary co-infection of Pneumocystis jirovecii and Aspergillus species (OFID) Impact of fluconazoleon outcomes of patients with primary pulmonary coccidioidomycosis (CID) Parasitic Comparative outcomes of Babesiosis in immunocompromised and non-immunocompromised hosts (CID) Miscellaneous Hidradenitis suppurativa (LANCET) A severe case associated with mixed infections of Pasteurella multocida, Bacteroides pyogenes and Fusobacterium necrophorum due to a snow leopard bite (CMI: Clinical Microbiology and Infection) INSIDE-OUT: Introduction of speakers at IDWeek events (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
Join us on our latest episode where we try the most consumed spirit in Japan, Shochu. This Japanese distilled beverage is typically distilled from rice, barley, sweet potatoes, buckwheat, or brown sugar, though it is sometimes produced from other ingredients such as chestnut, sesame seeds, potatoes, or even carrots. The main crucial ingredient in shochu is Koji and is a cooked grain (rice, soybeans or barley, etc) that has been inoculated with a fermentation culture called Aspergillus oryzae, koji mold. Koji is prepared by adding koji mold to steamed grains, then carefully kept in warm, humid conditions that promote growth. Rice is the most frequently used grain for making koji.Is Shochu good? Does it really deserve to be the most consumed spirit in Japan? Is it worth it? Only one way to find out...Special guest on this episode is our friend Brandon from Ethereal Brewing and The Void Sake Company in Lexington, KY.https://www.satsuma.co.jp/english/con-shiru-shochu.htmlhttps://honkakushochu-awamori.jp/english/professional/shochu-production-method/koji/#newrelease #shochu #koji #spiritreviews #drinkreview #podcast #isitworthit #arsenicculture https://www.youtube.com/@arsenicculturehttps://instagram.com/arsenicculturehttps://tiktok.com/@arsenicculturehttps://www.facebook.com/arsenicculture/https://x.com/arseniccultureShochu And The Mold That Makes IT Great-E98https://www.youtube.com/@arsenicculturehttps://instagram.com/arsenicculturehttps://tiktok.com/@arsenicculturehttps://www.facebook.com/arsenicculture/https://x.com/arsenicculture
In December, UNESCO recognized “Traditional Sake Making Techniques” as Japan's latest example of Intangible Cultural Heritage. Andy and Jim have questions, and maybe even a few answers, about what exactly that might mean. The key is, of course, koji and its use in alcoholic fermentation in Japan. Come take a listen as our hosts explore the implications for nihonshu and its future. Vocabulary for this episode: Barakoji バラ麹 - Japan's particular style of sprinkling Aspergillus oryzae spores over loose rice to make koji. Mochikoji 餅麹 - One Japanese term for the common Chinese style of cake fermentation starter, called sometime jiuqu or qu. Basically, a cake of rice flour or other starch mixed with water and inoculated with various microbes including Apergillus or Rhizopus molds. Recommendations: Andy - Daigorei from Bajo Shuzo Don't forget to support us on Patreon at https://www.patreon.com/SakeDeepDive Also, check out Andy's new sake tours at: https://www.originsaketours.com/ And buy Jim's book, Discovering Yamaguchi Sake wherever you order your books (print and ebook available)! Our theme music is from Lotus Lane by The Loyalist - Preconceived Notions Available at https://soundcloud.com/preconceived-notions Under a Creative Commons — Attribution 3.0 Unported— CC BY 3.0 Free Download / Stream: https://bit.ly/lotus-lane Music promoted by Audio Library https://youtu.be/1YVHRMVwwHg
Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Fungal diseases: Health burden, neglectedness, and potential interventions, published by Rethink Priorities on September 4, 2024 on The Effective Altruism Forum. Editorial note This report is a "shallow" investigation, as described here, and was commissioned by Open Philanthropy and produced by Rethink Priorities from January to February 2023. We revised the report for publication. Open Philanthropy does not necessarily endorse our conclusions, nor do the organizations represented by those who were interviewed. Our report focuses on exploring fungal diseases as a potential new cause area for Open Philanthropy. We assessed the current and future health burden of fungal diseases, provided an overview of current interventions and the main gaps and barriers to address the burden, and discussed some plausible options for philanthropic spending. We reviewed the scientific and gray literature and spoke with five experts. While revising the report for publication, we learned of a new global burden study ( Denning et al., 2024) whose results show an annual incidence of 6.5 million invasive fungal infections, and 3.8 million total deaths from fungal diseases (2.5 million of which are "directly attributable" to fungal diseases). The study's results align with this report's estimate of annual 1.5 million to 4.6 million deaths (80% confidence) but were not considered in this report. We don't intend this report to be Rethink Priorities' final word on fungal diseases. We have tried to flag major sources of uncertainty in the report and are open to revising our views based on new information or further research. Executive summary While fungal diseases are very common and mostly mild, some forms are life-threatening and predominantly affect low- and middle-income countries (LMICs). The evidence base on the global fungal disease burden is poor, and estimates are mostly based on extrapolations from the few available studies. Yet, all experts we talked to agree that current burden estimates (usually stated as >1.7M deaths/year) likely underestimate the true burden. Overall, we think the annual death burden could be 1.5M - 4.6M (80% CI), which would exceed malaria and HIV/AIDS deaths combined.[1] Moreover, our best guess is that fungal diseases cause 8M - 49M DALYs (80% CI) per year, but this is based on our own back-of-the-envelope calculation of high-uncertainty inputs. Every expert we spoke with expects the burden to increase substantially in the future, though no formal estimates exist. We project that deaths and DALYs could grow to approximately 2-3 times the current burden until 2040, though this is highly uncertain. This will likely be partly due to a rise in antifungal resistance, which is especially problematic as few treatment classes exist and many fungal diseases are highly lethal without treatment. We estimate that only two diseases (chronic pulmonary aspergillosis [CPA] and candidemia/invasive candidiasis [IC/C]) account for ~39%-45% of the total death and DALY burden. Moreover, a single fungal pathogen (Aspergillus fumigatus) accounts for ~50% of the burden. Thus, much of the burden can be reduced by focusing on only a few of the fungal diseases or on a few pathogens. Available estimates suggest the top fungal diseases have highest burdens in Asia and LMICs, and that they most affect immunocompromised individuals. Fungal diseases seem very neglected in all areas we considered (research/R&D, advocacy/lobbying, philanthropic spending, and policy interventions) and receive little attention even in comparison to other diseases which predominantly affect LMICs. For example, we estimate the research funding/death ratio for malaria to be roughly 20 times higher than for fungal diseases. Moreover, fewer than 10 countries have national surveillance systems for fungal infections, an...
Episode 173: Acute OsteomyelitisFuture Dr. Tran explains the pathophysiology of osteomyelitis and describes the presentation, diagnosis and management of acute osteomyelitis. Dr. Arreaza provides information about Written by Di Tran, MSIII, Ross University School of Medicine. Editing and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.What is osteomyelitis?Osteomyelitis, in simple terms, is an infectious disease that affects both bone and bone marrow and is either acute or chronic. According to archaeological findings of animal fossils with a bone infection, osteomyelitis was more than likely to be known as a “disease for old individuals”.Our ancestors over the years have used various vocabulary terms to describe this disease until a French surgeon, Dr. Nelaton, came up with the term “Osteomyelitis” in 1844. This is the beauty of medical terms, Latin sounds complicated for some people, but if you break up the term, it makes sense: Osteo = bone, myelo = marrow, itis = inflammation. So, inflammation of the bone marrow.Traditionally, osteomyelitis develops from 3 different sources:First category is the “hematOgenous” spread of the infection within the bloodstream, as in bacteremia. It is more frequent in children and long bones are usually affected. [Arreaza: it means that the infection started somewhere else but it got “planted” in the bones]Second route is “direct inoculation” of bacteria from the contiguous site of infection “without vascular insufficiency”, or trauma, which may occur secondary to fractures or surgery in adults. In elderly patients, the infection may be related to decubitus ulcers and joint replacements.And the third route is the “contiguous” infection “with vascular insufficiency”, most seen in a patient with a diabetic foot infection.Patients with vascular insufficiency often have compromised blood supply to the lower extremities, and poor circulation impairs healing. In these situations, infection often occurs in small bones of the feet with minimal to no pain due to neuropathy.They can have ulcers, as well as paronychia, cellulitis, or puncture wounds.Thus, the importance of treating onychomycosis in diabetes because the fungus does not cause a lot of problems by itself, but it can cause breaks in the nails that can be a port of entry for bacteria to cause severe infections. Neuropathy is an important risk factor because of the loss of protective sensation. Frequently, patients may step on a foreign object and not feel it until there is swelling, purulent discharge, and redness, and they come to you because it “does not look good.”Acute osteomyelitis often takes place within 2 weeks of onset of the disease, and the main histopathological findings are microorganisms, congested blood vessels, and polymorphonuclear leukocytes, or neutrophilic infiltrates.What are the bugs that cause osteomyelitis?Pathogens in osteomyelitis are heavily depended on the patient's age. Staph. aureus is the most common culprit of acute hematogenous osteomyelitis in children and adults. Then comes Group A Strep., Strep. pneumoniae, Pseudomonas, Kingella, and methicillin-resistant Staph. aureus. In newborns, we have Group B Streptococcal. Less common pathogens are associated with certain clinical presentations, including Aspergillus, Mycobacterium tuberculosis, and Candida in the immunocompromised.Salmonella species can be found in patients with sickle cell disease, Bartonella species in patients with HIV infection, and Pasteurella or Eikenella species from human or animal bites.It is important to gather a complete medical history of the patient, such as disorders that may put them at risk of osteomyelitis, such as diabetes, malnutrition, smoking, peripheral or coronary artery disease, immune deficiencies, IV drug use, prosthetic joints, cancer, and even sickle cell anemia. Those pieces of information can guide your assessment and plan.What is the presentation of osteomyelitis?Acute osteomyelitis may present symptoms over a few days from onset of infection but usually is within a 2-week window period. Adults will develop local symptoms of erythema, swelling, warmth, and dull pain at the site of infection with or without systemic symptoms of fever or chills.Children will also be present with lethargy or irritability in addition to the symptoms already mentioned.It may be challenging to diagnose osteomyelitis at the early stages of infection, but you must have a high level of suspicion in patients with high risks. A thorough physical examination sometimes will show other significant findings of soft tissue infection, bony tenderness, joint effusion, decreased ROM, and even exposed bone. Diagnosis.As a rule of thumb, the gold standard for the diagnosis of osteomyelitis is bone biopsy with histopathology findings and tissue culture. There is leukocytosis, but then WBC counts can be normal even in the setting of acute osteomyelitis.Inflammatory markers (CRP, ESR) are often elevated although both have very low specificity. Blood cultures should always be obtained whenever osteomyelitis is suspected. A bone biopsy should also be performed for definitive diagnosis, and specimens should undergo both aerobic and anaerobic cultures. In cases of osteomyelitis from diabetic foot infection, do the “probe to bone” test. What we do is we use a sterile steel probe to detect bone which is helpful for osteomyelitis confirmation.Something that we can't miss out on is radiographic imaging, which is quite important for the evaluation of osteomyelitis. Several modalities are useful and can be used for the work-up plan; plain radiographs often are the very first step in the assessment due to their feasibility, low cost, and safety. Others are bone scintigraphy, CT-scan, and MRI. In fact, the MRI is widely used and provides better information for early detection of osteomyelitis than other imaging modalities. It can detect necrotic bone, sinus tracts, and even abscesses. We look for soft tissue swelling, cortical bone loss, active bone resorption and remodeling, and periosteal reaction. Oftentimes, plain radiography and MRI are used in combination. Treatment:Treatment of osteomyelitis actually is a teamwork effort among various medical professionals, including the primary care provider, the radiologist, the vascular, the pharmacist, the podiatrist, an infectious disease specialist, orthopedic surgeons, and the wound care team.Something to take into consideration, if the patient is hemodynamically stable it is highly recommended to delay empirical antibiotic treatment 48-72 hours until a bone biopsy is obtained. The reason is that with percutaneous biopsy ideally done before the initiation of antibiotic treatment, “the microbiological yield will be higher”.We'll have a better idea of what particular bugs are causing the problem and guide the treatment appropriately. The choice of antibiotic therapy is strongly determined by susceptibilities results. The antibiotic given will be narrowed down only for the targeted susceptible organisms. In the absence of such information, or when a hospitalized patient presents with an increased risk for MRSA infection, empiric antibiotic coverage is then administered while awaiting culture results. It should be broad-spectrum antibiotics and include coverage for MRSA, broad gram-negative and anaerobic bacteria. For example, vancomycin plus piperacillin-tazobactam, or with broad-spectrum cephalosporin plus clindamycin. Treatment will typically be given for 4 to 6 weeks.The duration between 4-6 weeks is important for complete healing, but a small study with a small sample showed that an even shorter duration of 3 weeks may be effective, but more research is needed. In certain situations, surgery is necessary to preserve viable tissue and prevent recurrent infection, especially when there are deep abscesses, necrosis, or gangrene, amputation or debridement is deemed appropriate. If the infected bone is completely removed, patients may need a shorter course of antibiotics, even a few days only. Amputation can be very distressing, especially when we need to remove large pieces of infected bone, for example, a below-the-knee amputation. We need to be sensitive to the patient's feelings and make a shared decision about the best treatment for them.In patients with diabetes, additional care must be taken seriously, patient education about the need for compliance with treatment recommendations, with careful wound care, and good glycemic control are all beneficial for the healing and recovery process. Because this is a very common problem in the clinic and at the hospital, we must keep our eyes wide open and carefully assess patients with suspected osteomyelitis to detect it promptly and start appropriate treatment. Adequate and timely treatment is linked to fewer complications and better outcomes._________________________Conclusion: Now we conclude episode number 173, “Acute Osteomyelitis.” Future Dr. Tran explained the pathophysiology, diagnosis, and management of osteomyelitis. A bone biopsy is the ideal method of diagnosis. Delaying antibiotic treatment a few days until you get a biopsy is allowed if the patient is stable, but if the patient is unstable, antibiotics must be started promptly. Dr. Arreaza mentioned the implications of amputation and that we must discuss this treatment empathically with our patients. This week we thank Hector Arreaza and Di Tran. Audio editing by Adrianne Silva.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Bury DC, Rogers TS, Dickman MM. Osteomyelitis: Diagnosis and Treatment. Am Fam Physician. 2021 Oct 1;104(4):395-402. PMID: 34652112.Cunha BA. Osteomyelitis in elderly patients. Clin Infect Dis. 2002 Aug 1;35(3):287-93. doi: 10.1086/341417. Epub 2002 Jul 11. PMID: 12115094.Fritz JM, McDonald JR. Osteomyelitis: approach to diagnosis and treatment. Phys Sportsmed. 2008 Dec;36(1):nihpa116823. doi: 10.3810/psm.2008.12.11. PMID: 19652694; PMCID: PMC2696389.Hatzenbuehler J, Pulling TJ. Diagnosis and management of osteomyelitis. Am Fam Physician. 2011 Nov 1;84(9):1027-33. PMID: 22046943.Hofstee MI, Muthukrishnan G, Atkins GJ, Riool M, Thompson K, Morgenstern M, Stoddart MJ, Richards RG, Zaat SAJ, Moriarty TF. Current Concepts of Osteomyelitis: From Pathologic Mechanisms to Advanced Research Methods. Am J Pathol. 2020 Jun;190(6):1151-1163. doi: 10.1016/j.ajpath.2020.02.007. Epub 2020 Mar 16. PMID: 32194053.Momodu II, Savaliya V. Osteomyelitis. [Updated 2023 May 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK532250/Royalty-free music used for this episode: Trap Chiller by Gushito, downloaded on Nov 06, 2023, from https://www.videvo.net
So many amazing Canna-people, so little time. CannMed 24 was sublime! Here are the another batch of clips we got!Ben Cameransi – Mingowood Pharmacal, LLC - Dr. Benjamin Cameransi, MD, DABA is a Board-Certified Anesthesiologist, with a extensive background in pain management. He has started four Biotech Companies. He was involved in the development of Ryanodex™, a treatment for Malignant Hyperthermia. But wait, there's more… Acidic cannabinoids aren't very stable when they are extracted and purified. Dr. Camersani's team at Mingowood Pharmacal has a way to fix that.Taz Turner -CordovaCann Corp - Taz has the top three attributes we look for in a guest. He knows where Manitoba is located. He's a finance guy who spoke intelligently during his Capital Markets Panel. He is fun to chat to at a breakfast information session. Taz tells us how it is surprisingly difficult to get investment into the cannabis space in 2024. But, numbers and valuation guys like him (who also speak cannabis) are slowly convincing others that opportunities abound.Melissa Moore - Professor, Cannabis Horticulture & Biology, SUNY Niagara Community College. Melissa Moore developed some of her horticultural chops in Northern California, but now passes on her knowledge in Buffalo, NY. She was very helpful getting pics of Trevor during his Capital Markets Panel and then she sparked some intense Aspergillus discussions. Professor Moore tells us why cleanliness is next to godliness in your grow room and, hear why Kirk is frothing at the mouth to pick her brain about how to grow plants better.Ben Cameransi - LinkedInMingowood Pharmacal, LLC - WebsiteTaz Turner -LinkedInCordovaCann Corp. - websiteMelissa Moore - LinkedInSUNY Niagara Horticultural Cannabis Classes - websiteMusic by:Stills-Young Band - Midnight on the Bay -YouTubeAdditional Music:Desiree Dorion desireedorion.comMarc Clement - FacebookTranscripts, papers and so much more at: reefermed.ca
Doctor Theodore Yates visits a patient, grasping at straws to try and find the origin of the Rot—a mysterious illness that is plaguing his town.Find us on Tumblr @TheIchorousRotPod to find out more, or visit our website: https://theichorousrotpod.carrd.co/. Transcripts available at: https://drive.google.com/drive/folders/1oaM9LM7AfqWZ3e-8a7dgvuUgkY7PPrkZ Find all of the Podcast Jam pilots here: https://shows.acast.com/podcast-jamThis episode features Charlie Hyde as Theodore Yates, Grimm Blorbeaux as Alonzo, Niall Rowan as John Marsh, and Moookar as Penelope Pembroke. It was written by Sam Coy and edited by Charlie Hyde, with music by Grimm Blorbeaux.Content warnings: Discussion of death, illness, detailed description of injury. Hosted on Acast. See acast.com/privacy for more information.
In this podcast, we're going to talk about some of the side effects of consuming too much sugar. Some of the well-known side effects of sugar include fatigue, brain fog, belly fat, carb cravings, and cavities. Is there a difference between sugar and carbohydrates? A carbohydrate consists of sugar, fiber, and starch. Starches are called polysaccharides, meaning many sugars or multiple sugar molecules connected together. Starches raise blood sugar levels significantly more than sugar. Starches like maltodextrin, modified food starch, and modified corn starch have a much higher glycemic index than sugar. Here are 7 surprising signs that you're consuming too much sugar: 7. Reduced collagen Reduced collagen will result in loose, wrinkled skin and premature aging. 6. Chronic white tongue Candida from too much sugar will cause you to have a white tongue. You won't be able to get rid of it without eliminating sugar from the diet. 5. Chronic sinus problems Most chronic sinus problems are caused by a fungus called Aspergillus that feeds on sugar. 4. Red or pink gums Red or pink on your toothbrush after brushing could signify a mild case of scurvy or vitamin C deficiency. High sugar consumption blocks vitamin C. 3. Low testosterone Low testosterone can cause erectile dysfunction, decreased libido, and difficulty building muscle. 2. Susceptibility to infection Too much sugar can weaken your immune system, making you more vulnerable to infection. 1. High adrenaline levels Too much sugar damages the cell's ability to make energy in the mitochondria. To compensate, the body produces more adrenaline.
Chronic sinus infections can be frustrating and uncomfortable. While many people turn to antibiotics for relief, they may not realize that these medications only target bacteria and can worsen the situation if the infection is fungal. Fungal infections can be even more problematic, particularly those caused by the invasive fungus Aspergillus. This fungus can break down the lining of your sinus cavities and potentially damage bone and tissue in other areas. It also thrives in environments with oxygen and moisture. If you have a weakened immune system due to conditions such as diabetes, HIV, or a poor diet high in sugar and refined carbs, Aspergillus can take advantage and cause further harm. In fact, it has been known to target and downgrade vitamin D receptors in the body, leading to a compromised immune system. To combat this fungal issue, you can try incorporating natural remedies into your routine. One powerful remedy is garlic oil, which has been shown to inhibit the growth of fungus and bacteria. Oregano oil is also effective in fighting bacteria, yeast, and mold. Both can be diluted with coconut oil which contains compounds that boost the immune system and have anti-fungal properties. Add 5 drops of garlic oil and 5 drops of oregano oil to one teaspoon. Then, add just enough coconut oil until you have one full teaspoon of this mixture. Consider taking this daily for one month to allow it to gradually balance out your body's microorganisms. You can also include xylitol, curcumin, or aloe vera for added benefits. Blue light therapy may also be beneficial, as well as red light therapy if you've had surgery on your sinuses. DATA: https://turnontheblue.com/safe-blue-l...
I'm often asked whether or not there is a correlation between breast implants and mold toxicity. This is a topic that sparks considerable interest and concern among patients, as they seek to understand any possible implications for their health and well-being given the prevalence of mold-related health issues and the widespread use of breast implants. In this episode, we aim to raise awareness and address such inquiries with clarity and accuracy, drawing upon both scientific evidence and clinical experience to provide informed insights and guidance to my patients. Mold toxicity and Breast Implant Illness There's considerable evidence suggesting a connection between high mold toxicity and breast implant illness in women. Through extensive testing, it's been found that around six of thousands of tested samples have shown the presence of fungi, which includes mold. When I look at the numbers, it's clear that the instances of confirmed mold presence in breast implant illness cases are extremely low. Typically, there's a specific explanation for these cases, like one patient who was a triathlete and likely picked up mold during swimming competitions. It's crucial to recognize that water harbors various bacteria, fungi, and viruses, contributing to these isolated incidents. However, in my extensive experience working with patients who have breast implants, I've observed that mold exposure is often tied to environmental factors such as air or food contamination. For example, Aspergillus, a prevalent type of black mold, presents a significant risk. This mold can thrive in various environments, including damp areas in homes or buildings, and can contaminate food sources if proper storage and handling practices are not followed. Additionally, mold tends to grow more in certain weather conditions or times of the year, so patients need to be aware of possible exposure risks. While there are rare cases of mold directly in breast implants, the main focus should be on tackling environmental sources of mold to lower health risks for patients with implants. Food and Wine Safety, Including Ochratoxin and Mold in Coffee and Grains When it comes to items like food and wine, it's important to be aware of the presence of ochratoxin, a type of mold toxin commonly found in wine worldwide. While the European Union has strict guidelines regulating ochratoxin levels in wine, the same standards aren't in place in the United States. This means consumers need to exercise caution, particularly when it comes to wine consumption. Choosing wines labeled as dry farm or organic can provide a more reliable option, particularly for individuals particularly sensitive to mold toxins. Dry farming techniques involve cultivating grapes without irrigation, relying solely on natural rainfall, which can reduce the risk of mold growth compared to grapes grown using conventional methods. Coffee production similarly poses a risk of mold contamination, so it's important to look for mold-free options. Brands like Bulletproof Coffee, founded by Dave Asprey, have gained popularity for focusing on providing mold-free coffee products. Being mindful of mold contamination in various food items, including grains and cereals, is essential for maintaining overall health and minimizing exposure to mold toxins. Breast Implant Illness, Toxicity Testing, and Detoxification Protocols The occurrence of mold exposure stems from a combination of factors, as I've observed in many of my patients and personally experienced living in Austin, where severe winter weather and inadequate home infrastructure can lead to water leaks and mold growth. Given these risks, I advise individuals who are particularly sensitive to mold to consider investing in air filters. However, when considering these various options, it's crucial to ensure they can effectively filter mold spores, which are smaller than bacteria, to safeguard against health issues. This is particularly important for individuals who may have genetic variations impacting their detoxification pathways, as they may be more susceptible to the adverse effects of mold exposure. Beyond simply filtering out mold spores, it's also essential to consider the overall air quality within the home. Factors such as humidity levels, ventilation, and the presence of other pollutants can all contribute to the proliferation of mold and impact indoor air quality. As a plastic surgeon who focuses on breast implant illness, my team and I are experienced in understanding the genetic factors and toxicities that affect our patients. We conduct urine toxicity tests and utilize glutathione challenges to assess their problems and tailor treatment plans accordingly. By focusing on improving the quality of fluid, food, and air intake, we aim to reduce inflammation, which we know correlates with symptom improvement. Addressing mold exposure requires personalized protocols based on toxicity testing results and individual tolerance levels. Given the prevalence of sensitivity among our patients, careful consideration and tailored detoxification strategies are essential for managing their health effectively.
Wednesday - January 3, 2024In the first half, Dr. Joel Wallach discussed the human body's ability to achieve natural healing with the benefits of remedies and supplements that aid in the recovery from chronic conditions. Historically, human societies got minerals from glacial melt that irrigated their fields, and wood and coal ashes from their cooking, but with the advent of electricity, that all changed, and now people have deficiencies which open them up to various ailments and diseases, he argued. To combat various bacteria and infections, he mentioned that he consumes drops of colloidal silver.Wallach cautioned against eating peanut butter or peanuts. Peanuts are grown in the ground and are often infested with a fungus called Aspergillus that produces a toxin associated with liver cancer, he stated. He also believes that it's important to avoid eating various grains like wheat because they contain gluten, which he says destroys the lining of the intestine and prevents food absorption. "Gluten has killed more people than bullets," he declared. Wallach also described placing liquid minerals directly on the body, which can be absorbed through the skin and have beneficial effects.------------In the latter half, publisher of Mysterious World books, Doug Elwell shared his research on ancient references to Planet X and why he believes the planet is the harbinger of epic change. According to Elwell, there is evidence that the Star of Bethlehem was really Planet X, that it comes toward Earth around every 2,000 years, and that it has been associated with ancient cataclysms. We could see the return of Planet X in our lifetimes, possibly in the next few years, he continued. In his interpretation, Planet X's orbital characteristics are central to different parts of the Bible and to the Book of Revelation, in particular, which he said indicates that Planet X will eventually replace Earth as the new home for humanity.Elwell talked about an ancient race of giants that interbred with humanity before and after the great flood. While the Nephilim were terrestrial, there is evidence that they may have engaged in space travel, he suggested. He also delved into mysteries and riddles of the Sphinx, and said one of the ancient tribes of Israel, Gad, dug into the Sphinx looking for a secret chamber (similar to what Edgar Cayce had said about a Hall of Records being hidden there). Elwell interpreted a passage in Deuteronomy as being about the Sphinx, and that the Gad found an ancient stone known as the 'Lawgiver' there, which could be used to communicate directly with God. This object was like a proto Ark of the Covenant, he added. --- Send in a voice message: https://podcasters.spotify.com/pod/show/georgenoory/message
Wednesday - January 3, 2024In the first half, Dr. Joel Wallach discussed the human body's ability to achieve natural healing with the benefits of remedies and supplements that aid in the recovery from chronic conditions. Historically, human societies got minerals from glacial melt that irrigated their fields, and wood and coal ashes from their cooking, but with the advent of electricity, that all changed, and now people have deficiencies which open them up to various ailments and diseases, he argued. To combat various bacteria and infections, he mentioned that he consumes drops of colloidal silver.Wallach cautioned against eating peanut butter or peanuts. Peanuts are grown in the ground and are often infested with a fungus called Aspergillus that produces a toxin associated with liver cancer, he stated. He also believes that it's important to avoid eating various grains like wheat because they contain gluten, which he says destroys the lining of the intestine and prevents food absorption. "Gluten has killed more people than bullets," he declared. Wallach also described placing liquid minerals directly on the body, which can be absorbed through the skin and have beneficial effects.------------In the latter half, publisher of Mysterious World books, Doug Elwell shared his research on ancient references to Planet X and why he believes the planet is the harbinger of epic change. According to Elwell, there is evidence that the Star of Bethlehem was really Planet X, that it comes toward Earth around every 2,000 years, and that it has been associated with ancient cataclysms. We could see the return of Planet X in our lifetimes, possibly in the next few years, he continued. In his interpretation, Planet X's orbital characteristics are central to different parts of the Bible and to the Book of Revelation, in particular, which he said indicates that Planet X will eventually replace Earth as the new home for humanity.Elwell talked about an ancient race of giants that interbred with humanity before and after the great flood. While the Nephilim were terrestrial, there is evidence that they may have engaged in space travel, he suggested. He also delved into mysteries and riddles of the Sphinx, and said one of the ancient tribes of Israel, Gad, dug into the Sphinx looking for a secret chamber (similar to what Edgar Cayce had said about a Hall of Records being hidden there). Elwell interpreted a passage in Deuteronomy as being about the Sphinx, and that the Gad found an ancient stone known as the 'Lawgiver' there, which could be used to communicate directly with God. This object was like a proto Ark of the Covenant, he added. --- Send in a voice message: https://podcasters.spotify.com/pod/show/georgenoory/message
Wednesday - January 3, 2024In the first half, Dr. Joel Wallach discussed the human body's ability to achieve natural healing with the benefits of remedies and supplements that aid in the recovery from chronic conditions. Historically, human societies got minerals from glacial melt that irrigated their fields, and wood and coal ashes from their cooking, but with the advent of electricity, that all changed, and now people have deficiencies which open them up to various ailments and diseases, he argued. To combat various bacteria and infections, he mentioned that he consumes drops of colloidal silver.Wallach cautioned against eating peanut butter or peanuts. Peanuts are grown in the ground and are often infested with a fungus called Aspergillus that produces a toxin associated with liver cancer, he stated. He also believes that it's important to avoid eating various grains like wheat because they contain gluten, which he says destroys the lining of the intestine and prevents food absorption. "Gluten has killed more people than bullets," he declared. Wallach also described placing liquid minerals directly on the body, which can be absorbed through the skin and have beneficial effects.------------In the latter half, publisher of Mysterious World books, Doug Elwell shared his research on ancient references to Planet X and why he believes the planet is the harbinger of epic change. According to Elwell, there is evidence that the Star of Bethlehem was really Planet X, that it comes toward Earth around every 2,000 years, and that it has been associated with ancient cataclysms. We could see the return of Planet X in our lifetimes, possibly in the next few years, he continued. In his interpretation, Planet X's orbital characteristics are central to different parts of the Bible and to the Book of Revelation, in particular, which he said indicates that Planet X will eventually replace Earth as the new home for humanity.Elwell talked about an ancient race of giants that interbred with humanity before and after the great flood. While the Nephilim were terrestrial, there is evidence that they may have engaged in space travel, he suggested. He also delved into mysteries and riddles of the Sphinx, and said one of the ancient tribes of Israel, Gad, dug into the Sphinx looking for a secret chamber (similar to what Edgar Cayce had said about a Hall of Records being hidden there). Elwell interpreted a passage in Deuteronomy as being about the Sphinx, and that the Gad found an ancient stone known as the 'Lawgiver' there, which could be used to communicate directly with God. This object was like a proto Ark of the Covenant, he added. --- Send in a voice message: https://podcasters.spotify.com/pod/show/georgenoory/message
Wednesday - January 3, 2024In the first half, Dr. Joel Wallach discussed the human body's ability to achieve natural healing with the benefits of remedies and supplements that aid in the recovery from chronic conditions. Historically, human societies got minerals from glacial melt that irrigated their fields, and wood and coal ashes from their cooking, but with the advent of electricity, that all changed, and now people have deficiencies which open them up to various ailments and diseases, he argued. To combat various bacteria and infections, he mentioned that he consumes drops of colloidal silver.Wallach cautioned against eating peanut butter or peanuts. Peanuts are grown in the ground and are often infested with a fungus called Aspergillus that produces a toxin associated with liver cancer, he stated. He also believes that it's important to avoid eating various grains like wheat because they contain gluten, which he says destroys the lining of the intestine and prevents food absorption. "Gluten has killed more people than bullets," he declared. Wallach also described placing liquid minerals directly on the body, which can be absorbed through the skin and have beneficial effects.------------In the latter half, publisher of Mysterious World books, Doug Elwell shared his research on ancient references to Planet X and why he believes the planet is the harbinger of epic change. According to Elwell, there is evidence that the Star of Bethlehem was really Planet X, that it comes toward Earth around every 2,000 years, and that it has been associated with ancient cataclysms. We could see the return of Planet X in our lifetimes, possibly in the next few years, he continued. In his interpretation, Planet X's orbital characteristics are central to different parts of the Bible and to the Book of Revelation, in particular, which he said indicates that Planet X will eventually replace Earth as the new home for humanity.Elwell talked about an ancient race of giants that interbred with humanity before and after the great flood. While the Nephilim were terrestrial, there is evidence that they may have engaged in space travel, he suggested. He also delved into mysteries and riddles of the Sphinx, and said one of the ancient tribes of Israel, Gad, dug into the Sphinx looking for a secret chamber (similar to what Edgar Cayce had said about a Hall of Records being hidden there). Elwell interpreted a passage in Deuteronomy as being about the Sphinx, and that the Gad found an ancient stone known as the 'Lawgiver' there, which could be used to communicate directly with God. This object was like a proto Ark of the Covenant, he added. --- Send in a voice message: https://podcasters.spotify.com/pod/show/georgenoory/message
“I collect spores, molds and fungus” - Dr. Egon Spengler Dr. Ilan Schwartz MD PhD (@GermHunterMD) teaches us that we should always at least consider fungi in the differential diagnosis of unexplained sepsis, especially in patients with impaired immune systems or complex medical or surgical histories, and walks us through an approach to antifungals. Be sure to check out the Mycoses Study Group Education & Research Consortium (@MSG_ERC), an organization of clinicians who are dedicated to advancing diagnostics and treatment of fungal disease (where Dr. Schwartz serves on the board of directors!) Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments Intro Rapid fire questions, get to know our guest Intentionally vague case; When should we be worried about fungal infection? Overnight emergencies: Candidiasis and mucormycosis Starting empiric anti-fungals Testing basics: direct versus indirect Fungemia, fungal endocarditis Resistant candida; candida auris Pneumocystis jiroveci pneumonia Outro Credits Producer, Writer, Show Notes, Infographic/Cover Art: Beth Garbitelli MD Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP, Beth Garbitelli MD Reviewer: Emi Okamoto MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Ilan Schwartz MD, PhD Sponsor: Uncommon Goods To get 15% off your next gift, go to uncommongoods.com/CURB. Sponsor: NetSuite Go to NetSuite.com/CURBSIDERS to get your own KPI Checklist. Sponsor: Locumstory Get a comprehensive view of locums at locumstory.com.
Some people in the cannabis industry are questioning whether it is appropriate or necessary to test inhaled cannabis products for pathogenic Aspergillus. Full disclosure, we at Medicinal Genomics sell qPCR testing kits designed to detect pathogenic Aspergillus on cannabis products. We have also published several resources on our website that describe the potential harms that can be caused by inhaling pathogenic Aspergillus spores and cite with more than 2 dozen Aspergilosis cases in cannabis users. We have also recommended that states that are considering cannabis testing regulations adopt pathogenic Aspergillus testing. Not because we sell Aspergillus tests, but because we want to protect patients. By almost any measure, cannabis is one of the most safe and effective medicines available. And in many cases, the potential harms that can come from using cannabis are not caused by the plant, but rather contaminants. And although cases are rare, The documented cases describing Aspergillosis deaths from contaminated cannabis vastly outnumber the published clinical risks for every other contaminant for which the cannabis industry tests. There are no documented deaths for cannabis-derived heavy metals, mycotoxins, pesticides or incorrect cannabinoid labeling. The same cannot be said So that is our position, but of course we acknowledge that we are biased, and we are not experts on pathogenic fungi; however, our guest today is. David W. Denning is a Professor of Infectious Diseases in Global Health at the University of Manchester in the United Kingdom. He was the founding president, executive director, and CEO of Global Action For Fungal Infections, an organization dedicated to reducing the worldwide burden of fungal disease. In 2016, he became the director of the National Aspergillosis Centre in Manchester, which treats patients with chronic pulmonary aspergillosis (CPA), and led the committee that developed the first CPA guidelines. He chairs the editorial board of a website which focusses on aspergillus and he leads an organisation which provides education on fungal diseases. In short, Dr. Denning is the leading authority on all things Aspergillus, and we asked him many of the questions that have been debated on social media recently, including: Should cannabis be tested for pathogenic Aspergillus Should there be an allowable limit for pathogenic Aspergillus? Is Apergillosis only a concern for immunocompromised patients? Are the number of Aspergillosis cases under reported? How difficult is Aspergillosis to diagnose and treat? How ubiquitous is Aspergillus in the air we breathe? and so much more. Thanks to This Episode's Sponsor: Modern Canna Modern Canna is regarded as Florida's first medical cannabis laboratory and one of the most trusted third party testing providers in the United States. The company's mission is to help set the standard for cannabis testing labs worldwide by providing the most accurate and efficient testing services, delivered with a sense of compassion, integrity, and moral obligation; and to attract and attain clients who value quality data that is verifiable, reproducible, and legally defensible. Modern Canna is the only Leafly Certified laboratory in the eastern United States and adheres to the industry's strictest SOPs and quality control standards. Modern Canna offers a wide variety of testing, rapid turnaround times, and consulting services to Florida Medical Marijuana Treatment Centers (MMTC's) and hemp businesses throughout the US. Learn more at moderncanna.com Additional Resources Too Many Mouldy Joints – Marijuana and Chronic Pulmonary Aspergillosis The Aspergillus website https://en.fungaleducation.org/ Submit an Abstract for CannMed 24 Review the Podcast! CannMed Archive CannMed Community Board [Facebook Group]
Berl Oakley and his team are using Aspergillus nidulans to degrade plastic and then using the secondary metabolites to then cure cancer, make antibiotics, statins, antifungals and more to save people's lives. Talk about killing two birds with one stone. Berl Oakley is the Irving Johnson Professor of Molecular and Cellular Biology at the University of Kansas dedicating the last 40+ years to solving the world's biggest problems with fungi. Sign up for our podcast giveaway here. Our next winner will be selected on October 30, 2023 and contacted via email.www.mushroomrevival.comWe are a functional mushroom company and make 100% certified USDA Organic and Vegan mushroom supplements. We are transparent with our lab results, and use actual fruiting bodies aka mushrooms! We provide our supplements in tincture, capsule, powder, and delicious gummy form. Energy (Cordyceps): Need a little pick-me-up before a workout or when you're picking up your kids from school? The Energy Cordyceps is the mushy match for you.Focus (Lion's Mane): Needing a little more focus in your daily life? Lion's Mane is known to be the mushroom for the brain and may support cognitive function.Calm (Reishi): Looking for some tranquility and zen in your life? Reishi will bring you into the zen state of mind you've been searching for.Daily 10 (Mushroom Mix): It's like having 10 bodyguard mushrooms fighting off all those bad guys. This is a good place to start as it contains all of the daily mushies you need. Not sure where to begin? Take our mushroom quiz here.Use code ‘PODTREAT' for a 30% discount.
This week we welcome Drs. Dwayne Elmore and Bronson Strickland to school us all on aflatoxin. Aflatoxins are produced by a couple of species of fungi in the genus Aspergillus that can appear in a variety of situations, and when ingested can be harmful to the very birds and mammals we cherish. Our expert guests thoroughly explain aflatoxin, practices we can follow to help prevent it, what to do if we discover molded feed, and then offer some feed solutions that can help. Anyone that feeds corn or uses feed based attractants needs to pay attention and be informed. Respect the science and the game we love. Listen, Learn and Be a Responsible Gamekeeper. Show Notes:MSU Deer Lab Support the showStay connected with GameKeepers: Instagram: @mossyoakgamekeepers Facebook: @GameKeepers Twitter: @MOGameKeepers YouTube: @MossyOakGameKeepers Website: https://mossyoakgamekeeper.com/ Subscribe to Gamekeepers Magazine: https://bit.ly/GK_Magazine Buy a Single Issue of Gamekeepers Magazine: https://bit.ly/GK_Single_Issue Join our Newsletters: Field Notes - https://bit.ly/GKField_Notes | The Branch - https://bit.ly/the_branch Have a question for us or a podcast idea? Email us at gamekeepers@mossyoak.com
On episode #33 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/6 – 7/19/23. Host: Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Early antiretroviral therapy not associated with higher cryptococcal Meningitis mortality in people with HIV in high-income countries (CID) Implementing a rapid Antiretroviral therapy program using starter packs for emergency department patients diagnosed with HIV infection (OFID) Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk Penicillin allergy (JAMA) Infectious diseases consultation associated with reduced mortality in gram-negative bacteremia (CID) Positive impact of [18F]FDG-PET/CT on mortality in patients with Staphylococcus aureus Bacteremia explained by immortal time bias (CID) Azithromycin for bacterial watery diarrhea (JID) Periprosthetic joint infection: current clinical challenges (CID) Old World medieval Treponema pallidum complex treponematosis (JID) Clinical Impact of polymerase chain reaction–based Aspergillus and Azole resistance detection in invasive aspergillosis (CID) Superior accuracy of Aspergillus plasma cell-free DNA PCR over serum galactomannan for the diagnosis of invasive aspergillosis (CID) Tafenoquine co-administered with dihydroartemisinin–piperaquine for the radical cure of Plasmodium vivax malaria (The Lancet) Doubling of cyclosporiasis cases partially attributable to a salad kit (CDC) Efficacy and safety of adjunctive corticosteroids in the treatment of severe community-acquired pneumonia (BMC) Music is by Ronald Jenkees
This week the fellas chat "The Last Of Us". The HBO show depicts a world overrun by deadly fungi, but experts say the threat is all too real. Fungi can infect and control the brain, killing hundreds of thousands of people annually. The WHO's list of high-risk fungi includes Aspergillus fumigatus, Candida species, and Cryptococcosis neoformans. Cordyceps, the fungus depicted in the show, is real and can change an insect's behavior. Climate change's impact on fungi is also a concern, highlighting the need for more research to understand their potential impact on humans and the environment. Jer went to a medium and took a lil' something something from it. One man wears RayBan smart glasses to record his hallucinations. A baby is born a giant down in Brazil. For WHAT THE HELLTH?! Addicted to drugs or alcohol? No worries! Just grab a piece of skin, edit it with CRISPR, reattach it, and voila! You'll turn your nose up at that bottle of whiskey or that line of coke. Mice experiments were a success and now researchers are seeking FDA approval for human trials. In five years or so, you'll be saying goodbye to your secret stash and hello to addiction-free skin! Who knew the solution was just a small piece of skin away! Join the post-episode conversation over on Discord! https://discord.gg/expeUDN