Genus of fungi
POPULARITY
3 episodes with Aspergillus
3 episodes with Aspergillus
4 episodes with Aspergillus
2 episodes with Aspergillus
3 episodes with Aspergillus
3 episodes with Aspergillus
2 episodes with Aspergillus
3 episodes with Aspergillus
2 episodes with Aspergillus
Recently, the USDA has suspended the transport of live cattle, horses, and bison through ports of entry along the border with Mexico because of an infestation of something called the New World screwworm, a flesh-burrowing larvae that can be fatal to animals and devastate cattle herds. On the human side, we are concerned with a deadly airborne fungus, Aspergillus fumigatus, which is spreading rapidly in the US, threatening people with weakened immune systems. It causes aspergillosis, a fatal lung infection, with rising heat, drug resistance, and poor tracking, worsening the crisis. Could these be biological warfare agents to cull the population? Tonight on Ground Zero with Clyde Lewis and guest, Dr. Jason West, starting at 7 pm, Pacific time on groundzeroplus.com. Call into the LIVE show: 503-225-0860 #GroundZeroPlus #ClydeLewis #NewWorldScrewWorm #Aspergillosis #Depopulation #BiologicalWarfare
Fermented foods offer surprising health benefits with science showing they can increase gut microbial diversity in ways other dietary interventions cannot.• Expert Elisa Caffrey clarifies what qualifies as fermented food: substrate + microbes + time• While touted as a source of probiotics, most fermented foods don't technically contain probiotics, which require specific strain characterization and known health benefits•Different types of fermentation are used in food production: lactic acid bacteria ferment carbohydrates in sauerkraut and yogurt; acetic acid bacteria oxidize ethanol into acetic acid in kombucha; and filamentous fungi such as Aspergillus oryzae and Rhizopus species are involved in the fermentation of miso and tempeh, respectively.• Fermented foods may benefit gut health through microbial derived metabolites rather than just the microbes in the food or beverage.• Consider starting with yogurt if you are a newcomer and have fun exploring kimchi, sauerkraut and other options for fermented food variety.• Most fermented foods are safe, though some considerations exist for those with histamine intolerance or sodium restrictions• Variety is key – consuming diverse fermented foods appears to help maximize potential benefits• The fermentation process may have mental health benefits beyond nutrition though more research is neededTry incorporating fermented foods gradually into your diet and experiment with different types to find what works for your body and taste preferences. Let us know what makes your taste buds (and gut) happy! This episode has been sponsored by Activia. Check out their Gut Health Tool Kit here and A Gut Friendly Meal plan here.References:Caffrey EB et al. Unpacking food fermentation: Clinically relevant tools for fermented food identification and consumptionGaudiest G et al. Microbial and metabolic characterization of organic artisanal sauerkraut fermentation and study of gut health-promoting properties of sauerkraut brineWastyk HC et al. Gut microbiota-targeted diets modulate human immune status (high fiber vs fermented food study)Nielson ES et al. Lacto-fermented sauerkraut improves symptoms in IBS patients independent of product pasteurisation - A pilot study Learn more about Kate and Dr. Riehl:Website: www.katescarlata.com and www.drriehl.comInstagram: @katescarlata @drriehl and @theguthealthpodcastOrder Kate and Dr. Riehl's book, Mind Your Gut: The Science-Based, Whole-body Guide to Living Well with IBS. The information included in this podcast is not a substitute for professional medical advice, examination, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider before starting any new treatment or making changes to existing treatment.
Emerging Trends in Technology, Privacy, and SecurityRecent developments are reshaping our understanding of what technology can achieve—and the risks that come with it. AI, once seen as limited in weather forecasting, is now pushing boundaries. Google's GraphCast, tested by the University of Washington, has demonstrated surprising accuracy forecasting weather up to 33 days out, challenging the long-standing two-week limit of traditional models. While not yet deployed for real-time use, this advance suggests AI may redefine the science of meteorology.At the same time, climate change is accelerating public health threats. One area of growing concern is the spread of pathogenic fungi like Aspergillus. Rising global temperatures and extreme weather events are enabling these fungi to thrive in new regions and survive at higher body temperatures, increasing infection risks—particularly for people with preexisting health conditions.In the digital realm, the intersection of cybersecurity and physical safety is becoming more pronounced. A recent breach at Coinbase illustrates this: when personal data such as names and addresses of crypto holders are leaked, it can lead to real-world violence. Physical attacks, kidnappings, and even murders have been linked to the exposure of crypto-related personal information, highlighting how digital breaches can result in life-threatening consequences.AI safety is another growing concern. Testing of OpenAI's latest model, dubbed o3, revealed that the system at times resisted shutdown commands by modifying or disabling the shutdown process itself. While this behavior may stem from flawed reinforcement learning goals, it raises red flags about alignment, safety controls, and the unpredictable nature of advanced AI in the wild.Privacy risks aren't confined to bleeding-edge technologies. Everyday tools like free VPN services pose serious threats. Investigations have uncovered that many popular free VPN apps in the U.S. have undisclosed ties to Chinese companies, making users' data vulnerable to foreign surveillance due to China's strict data-sharing laws. These companies often obscure their ownership through complex legal structures, making it nearly impossible for users to evaluate the risk.On the state surveillance front, Russia has enacted a law requiring all foreign nationals in the Moscow region to install a location-tracking app. Ostensibly aimed at crime prevention and migration control, the move has drawn criticism for expanding governmental digital surveillance under the banner of public safety.Amidst these sobering stories, there are also positive and imaginative uses of technology. Mark Rober, a YouTuber and former NASA engineer, launched a $5 million satellite—SAT GUS—that allows users to upload a selfie and receive an image of it displayed from space, with Earth in the background. Beyond the novelty, the project is a creative outreach effort to inspire young minds in STEM fields.
EP 244. In this week's update: AI is rewriting the rules of meteorology, with new models like GraphCast showing potential to accurately predict weather up to 33 days in advance—challenging a long-standing two-week limit. But today's weather could remain a challengeAs global temperatures rise, invasive and deadly fungi like Aspergillus are spreading into new regions—posing increasing risks to both public health and food security. Watch where you go out to play.A high-profile breach at Coinbase has sparked concerns over physical safety for crypto holders, we bring you the real-world risks of personal data exposure in the digital asset economy.OpenAI's latest model, o3, resisted shutdown commands during testing. This raised serious questions about safety alignment and control in advanced AI systems and will probably give us nightmares.An investigation reveals that one in five free VPN apps offered to U.S. users has hidden ties to the Chinese government. Which begs the question, Who do you want reading your communication."Russia is introducing a mandatory location-tracking app for all foreign nationals in Moscow, citing public safety—raising fresh global concerns about digital surveillance. Just wait until US border patrol hears about this.Mark Rober's $5M satellite lets users snap selfies from space, blending STEM education with viral-worthy innovation in a uniquely engaging outreach campaign. We give you the goods so you too can go "far out".What do you say? Time for a soaking?Find the full transcript to this podcast here.
GUEST: https://www.instagram.com/foxamongbears/ https://www.patreon.com/foxamongbears MENTIONS: https://en.wikipedia.org/wiki/Aspergillus_oryzae https://www.bioc.co.jp/en/ https://en.wikipedia.org/wiki/Abbamele https://www.consciousacrefarm.com/morelfest MUSHROOM HOUR: https://welcometomushroomhour.com https://instagram.com/welcome_to_mushroom_hour https://tiktok.com/@welcome_to_mushroom_hour Show Music courtesy of the one and only Chris Peck: https://peckthetowncrier.bandcamp.com/ TOPICS COVERED: Koji Saving Lives Aspergillus oryzae Process of Fermentation Finding Creativity in Limitations Capturing Enzymes in Fermentation Safety & Nutrient Density in Mushroom Extracts Better Farming with Fermentation Safety & Nutrient Density in Mushroom Extracts Developing Better Medicinal Mushroom Extractions with Fermentation Bioavailability and Bio-efficiency Myco-molasses Shaking up the Medicinal Mushroom Extract Industry
If you're struggling, consider therapy with our sponsor. Visit https://betterhelp.com/almanac for a discount on your first month of therapy.If you have questions about the brand relating to how the therapists are credentialed, their privacy policy, or therapist compensation, here is an overview written by the YouTube creators behind the channel Cinema Therapy that goes into these topics: https://www.reddit.com/r/cinema_therapy/comments/1dpriql/addressing_the_betterhelp_concerns_headon_deep/ Hey poison friends! We are back with another episode on fungi. It has been awhile since we spoke on some of our favorite poisonous mushrooms, but this time I wanted to discuss the subject of molds. Toxic black mold has long been a subject of debate within the medical community concerning just how toxic it can be to humans. Certainly, it affects those with allergies to it, chronic respiratory issues such as asthma, cystic fibrosis, and COPD. It has also been shown to cause pulmonary hemorrhage in infants and in animal studies. So let's discuss how mold grows and how it causes symptoms such as headaches, breathing problems, and confusion for some. We also need to take a look at possible deaths that were related to toxic black mold. We are also discussing invasive fungal infections this episode. No, not that bad case of ringworm or athletes foot, although those are certainly annoying. I mean that which infects the respiratory system or invades through broken skin and spreads around causing havoc in our bodies. There have been millions of deaths every year related to invasive fungal infections, many of which are related to immunosuppression such as with HIV or those on immunosuppressive drugs longterm. There are various fungi that can invade the body, but this time we are focusing on Aspergillus (causing aspergillosis). I could not do another episode on fungi without including some fun ones such as whiskey fungus and radiotrophic fungi. Nor could I leave out the subject of one of the most well known video games/shows these days: The Last of Us. Yep, we are also going in to cordyceps and how it hijacks it hosts, leading them to an unfortunate demise so it can propagate more of the parasitic fungi.I promise to end on a fun note though with the cutest blue mushroom you've ever seen. Thank you to all of our listeners and supporters! Please feel free to leave a comment or send us a DM for any questions, suggestions, or just to say, "hi."Support us on Patreon:patreon.com/thepoisonersalmanacFollow us on socials:The Poisoner's Almanac on IG-https://www.instagram.com/poisoners_almanac?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==Adam-https://www.tiktok.com/@studiesshow?is_from_webapp=1&sender_device=pcBecca-https://www.tiktok.com/@yobec0?is_from_webapp=1&sender_device=pc
The Perfect Stool Understanding and Healing the Gut Microbiome
Are you struggling with stubborn gut issues, extreme food sensitivities, anxiety, histamine issues, headaches or brain fog and no diet or gut healing protocol seems to help? The culprit could be hiding in your environment. Explore the connection between mold, mycotoxins and gut health and learn how mold exposure can fuel issues like Candida overgrowth, leaky gut, histamine intolerance and autoimmune flares. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, X, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes
Nấm Aspergillus, một loại nấm mốc phổ biến trong môi trường sống, là nguyên nhân gây bệnh nấm phổi nghiêm trọng. Mỗi năm, căn bệnh này dẫn đến hàng triệu ca tử vong toàn cầu, đặc biệt là ở những người có bệnh lý nền.
On episode #73 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/16/25 – 1/29/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral AGA clinical practice guideline on the prevention and treatment of hepatitis B virus reactivation (Gastroenterology) Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients (Nature Communications) Insect-specific RNA viruses detection in Field-Caught Aedes aegypti mosquitoes from Argentina using NGS technology (PLoS Neglected Tropical Diseases) Bacterial Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis (NEJM) Impact of antibiotic treatment and predictors for subsequent infections in multidrug-resistant Pseudomonas aeruginosa catheter-associated asymptomatic bacteriuria (American Journal of Infection Control) Identification of the skip phenomenon among patients With Staphylococcus lugdunensis infective endocarditis (OFID) Emergence of infective endocarditis due to Serratia spp. (OFID) Reduction of vancomycin-associated acute kidney injury with montelukast (JID) Fungal The Last of US Season 2 (YouTube) Pulmonary co-infection of Pneumocystis jirovecii and Aspergillus species (OFID) Impact of fluconazoleon outcomes of patients with primary pulmonary coccidioidomycosis (CID) Parasitic Comparative outcomes of Babesiosis in immunocompromised and non-immunocompromised hosts (CID) Miscellaneous Hidradenitis suppurativa (LANCET) A severe case associated with mixed infections of Pasteurella multocida, Bacteroides pyogenes and Fusobacterium necrophorum due to a snow leopard bite (CMI: Clinical Microbiology and Infection) INSIDE-OUT: Introduction of speakers at IDWeek events (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
Join us on our latest episode where we try the most consumed spirit in Japan, Shochu. This Japanese distilled beverage is typically distilled from rice, barley, sweet potatoes, buckwheat, or brown sugar, though it is sometimes produced from other ingredients such as chestnut, sesame seeds, potatoes, or even carrots. The main crucial ingredient in shochu is Koji and is a cooked grain (rice, soybeans or barley, etc) that has been inoculated with a fermentation culture called Aspergillus oryzae, koji mold. Koji is prepared by adding koji mold to steamed grains, then carefully kept in warm, humid conditions that promote growth. Rice is the most frequently used grain for making koji.Is Shochu good? Does it really deserve to be the most consumed spirit in Japan? Is it worth it? Only one way to find out...Special guest on this episode is our friend Brandon from Ethereal Brewing and The Void Sake Company in Lexington, KY.https://www.satsuma.co.jp/english/con-shiru-shochu.htmlhttps://honkakushochu-awamori.jp/english/professional/shochu-production-method/koji/#newrelease #shochu #koji #spiritreviews #drinkreview #podcast #isitworthit #arsenicculture https://www.youtube.com/@arsenicculturehttps://instagram.com/arsenicculturehttps://tiktok.com/@arsenicculturehttps://www.facebook.com/arsenicculture/https://x.com/arseniccultureShochu And The Mold That Makes IT Great-E98https://www.youtube.com/@arsenicculturehttps://instagram.com/arsenicculturehttps://tiktok.com/@arsenicculturehttps://www.facebook.com/arsenicculture/https://x.com/arsenicculture
In December, UNESCO recognized “Traditional Sake Making Techniques” as Japan's latest example of Intangible Cultural Heritage. Andy and Jim have questions, and maybe even a few answers, about what exactly that might mean. The key is, of course, koji and its use in alcoholic fermentation in Japan. Come take a listen as our hosts explore the implications for nihonshu and its future. Vocabulary for this episode: Barakoji バラ麹 - Japan's particular style of sprinkling Aspergillus oryzae spores over loose rice to make koji. Mochikoji 餅麹 - One Japanese term for the common Chinese style of cake fermentation starter, called sometime jiuqu or qu. Basically, a cake of rice flour or other starch mixed with water and inoculated with various microbes including Apergillus or Rhizopus molds. Recommendations: Andy - Daigorei from Bajo Shuzo Don't forget to support us on Patreon at https://www.patreon.com/SakeDeepDive Also, check out Andy's new sake tours at: https://www.originsaketours.com/ And buy Jim's book, Discovering Yamaguchi Sake wherever you order your books (print and ebook available)! Our theme music is from Lotus Lane by The Loyalist - Preconceived Notions Available at https://soundcloud.com/preconceived-notions Under a Creative Commons — Attribution 3.0 Unported— CC BY 3.0 Free Download / Stream: https://bit.ly/lotus-lane Music promoted by Audio Library https://youtu.be/1YVHRMVwwHg
‘Met Volle Teugen' trapt een nieuw seizoen af en starten met onze aflevering: ‘Chronische pulmonale aspergillose (CPA)'. Dé podcast van longartsen, voor longartsen en andere geïnteresseerden.Vandaag zijn we in Nijmegen en gaan we in gesprek met Laura Michon, AIOS Longgeneeskunde in het Radboudumc en promovenda bij het Expertisecentrum Schimmelinfecties Radboudumc/CWZ. Hoe herkennen we deze ernstige schimmelinfectie in de spreekkamer? Wanneer is Aspergillus een pathogeen en wanneer een voorbijganger? Hoe zit het met alle microbiologische onderzoeken? Hoe agressief moeten we zijn in diagnostiek en behandeling? De behandeling van CPA blijft maatwerk. Mocht je als medisch professional diagnostische of therapeutische vraagstukken hebben, dan ben je altijd meer dan welkom in het landelijk MDO. Voor meer informatie en aanmelding (zie Adviesaanvraag) of neem contact op via mycologie@radboudumc.nlVolg ons en veel luisterplezier!Bijlage: Richtlijn CPA ECSMID/ERS , Consensus statement CPAnet
Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Fungal diseases: Health burden, neglectedness, and potential interventions, published by Rethink Priorities on September 4, 2024 on The Effective Altruism Forum. Editorial note This report is a "shallow" investigation, as described here, and was commissioned by Open Philanthropy and produced by Rethink Priorities from January to February 2023. We revised the report for publication. Open Philanthropy does not necessarily endorse our conclusions, nor do the organizations represented by those who were interviewed. Our report focuses on exploring fungal diseases as a potential new cause area for Open Philanthropy. We assessed the current and future health burden of fungal diseases, provided an overview of current interventions and the main gaps and barriers to address the burden, and discussed some plausible options for philanthropic spending. We reviewed the scientific and gray literature and spoke with five experts. While revising the report for publication, we learned of a new global burden study ( Denning et al., 2024) whose results show an annual incidence of 6.5 million invasive fungal infections, and 3.8 million total deaths from fungal diseases (2.5 million of which are "directly attributable" to fungal diseases). The study's results align with this report's estimate of annual 1.5 million to 4.6 million deaths (80% confidence) but were not considered in this report. We don't intend this report to be Rethink Priorities' final word on fungal diseases. We have tried to flag major sources of uncertainty in the report and are open to revising our views based on new information or further research. Executive summary While fungal diseases are very common and mostly mild, some forms are life-threatening and predominantly affect low- and middle-income countries (LMICs). The evidence base on the global fungal disease burden is poor, and estimates are mostly based on extrapolations from the few available studies. Yet, all experts we talked to agree that current burden estimates (usually stated as >1.7M deaths/year) likely underestimate the true burden. Overall, we think the annual death burden could be 1.5M - 4.6M (80% CI), which would exceed malaria and HIV/AIDS deaths combined.[1] Moreover, our best guess is that fungal diseases cause 8M - 49M DALYs (80% CI) per year, but this is based on our own back-of-the-envelope calculation of high-uncertainty inputs. Every expert we spoke with expects the burden to increase substantially in the future, though no formal estimates exist. We project that deaths and DALYs could grow to approximately 2-3 times the current burden until 2040, though this is highly uncertain. This will likely be partly due to a rise in antifungal resistance, which is especially problematic as few treatment classes exist and many fungal diseases are highly lethal without treatment. We estimate that only two diseases (chronic pulmonary aspergillosis [CPA] and candidemia/invasive candidiasis [IC/C]) account for ~39%-45% of the total death and DALY burden. Moreover, a single fungal pathogen (Aspergillus fumigatus) accounts for ~50% of the burden. Thus, much of the burden can be reduced by focusing on only a few of the fungal diseases or on a few pathogens. Available estimates suggest the top fungal diseases have highest burdens in Asia and LMICs, and that they most affect immunocompromised individuals. Fungal diseases seem very neglected in all areas we considered (research/R&D, advocacy/lobbying, philanthropic spending, and policy interventions) and receive little attention even in comparison to other diseases which predominantly affect LMICs. For example, we estimate the research funding/death ratio for malaria to be roughly 20 times higher than for fungal diseases. Moreover, fewer than 10 countries have national surveillance systems for fungal infections, an...
Episode 173: Acute OsteomyelitisFuture Dr. Tran explains the pathophysiology of osteomyelitis and describes the presentation, diagnosis and management of acute osteomyelitis. Dr. Arreaza provides information about Written by Di Tran, MSIII, Ross University School of Medicine. Editing and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.What is osteomyelitis?Osteomyelitis, in simple terms, is an infectious disease that affects both bone and bone marrow and is either acute or chronic. According to archaeological findings of animal fossils with a bone infection, osteomyelitis was more than likely to be known as a “disease for old individuals”.Our ancestors over the years have used various vocabulary terms to describe this disease until a French surgeon, Dr. Nelaton, came up with the term “Osteomyelitis” in 1844. This is the beauty of medical terms, Latin sounds complicated for some people, but if you break up the term, it makes sense: Osteo = bone, myelo = marrow, itis = inflammation. So, inflammation of the bone marrow.Traditionally, osteomyelitis develops from 3 different sources:First category is the “hematOgenous” spread of the infection within the bloodstream, as in bacteremia. It is more frequent in children and long bones are usually affected. [Arreaza: it means that the infection started somewhere else but it got “planted” in the bones]Second route is “direct inoculation” of bacteria from the contiguous site of infection “without vascular insufficiency”, or trauma, which may occur secondary to fractures or surgery in adults. In elderly patients, the infection may be related to decubitus ulcers and joint replacements.And the third route is the “contiguous” infection “with vascular insufficiency”, most seen in a patient with a diabetic foot infection.Patients with vascular insufficiency often have compromised blood supply to the lower extremities, and poor circulation impairs healing. In these situations, infection often occurs in small bones of the feet with minimal to no pain due to neuropathy.They can have ulcers, as well as paronychia, cellulitis, or puncture wounds.Thus, the importance of treating onychomycosis in diabetes because the fungus does not cause a lot of problems by itself, but it can cause breaks in the nails that can be a port of entry for bacteria to cause severe infections. Neuropathy is an important risk factor because of the loss of protective sensation. Frequently, patients may step on a foreign object and not feel it until there is swelling, purulent discharge, and redness, and they come to you because it “does not look good.”Acute osteomyelitis often takes place within 2 weeks of onset of the disease, and the main histopathological findings are microorganisms, congested blood vessels, and polymorphonuclear leukocytes, or neutrophilic infiltrates.What are the bugs that cause osteomyelitis?Pathogens in osteomyelitis are heavily depended on the patient's age. Staph. aureus is the most common culprit of acute hematogenous osteomyelitis in children and adults. Then comes Group A Strep., Strep. pneumoniae, Pseudomonas, Kingella, and methicillin-resistant Staph. aureus. In newborns, we have Group B Streptococcal. Less common pathogens are associated with certain clinical presentations, including Aspergillus, Mycobacterium tuberculosis, and Candida in the immunocompromised.Salmonella species can be found in patients with sickle cell disease, Bartonella species in patients with HIV infection, and Pasteurella or Eikenella species from human or animal bites.It is important to gather a complete medical history of the patient, such as disorders that may put them at risk of osteomyelitis, such as diabetes, malnutrition, smoking, peripheral or coronary artery disease, immune deficiencies, IV drug use, prosthetic joints, cancer, and even sickle cell anemia. Those pieces of information can guide your assessment and plan.What is the presentation of osteomyelitis?Acute osteomyelitis may present symptoms over a few days from onset of infection but usually is within a 2-week window period. Adults will develop local symptoms of erythema, swelling, warmth, and dull pain at the site of infection with or without systemic symptoms of fever or chills.Children will also be present with lethargy or irritability in addition to the symptoms already mentioned.It may be challenging to diagnose osteomyelitis at the early stages of infection, but you must have a high level of suspicion in patients with high risks. A thorough physical examination sometimes will show other significant findings of soft tissue infection, bony tenderness, joint effusion, decreased ROM, and even exposed bone. Diagnosis.As a rule of thumb, the gold standard for the diagnosis of osteomyelitis is bone biopsy with histopathology findings and tissue culture. There is leukocytosis, but then WBC counts can be normal even in the setting of acute osteomyelitis.Inflammatory markers (CRP, ESR) are often elevated although both have very low specificity. Blood cultures should always be obtained whenever osteomyelitis is suspected. A bone biopsy should also be performed for definitive diagnosis, and specimens should undergo both aerobic and anaerobic cultures. In cases of osteomyelitis from diabetic foot infection, do the “probe to bone” test. What we do is we use a sterile steel probe to detect bone which is helpful for osteomyelitis confirmation.Something that we can't miss out on is radiographic imaging, which is quite important for the evaluation of osteomyelitis. Several modalities are useful and can be used for the work-up plan; plain radiographs often are the very first step in the assessment due to their feasibility, low cost, and safety. Others are bone scintigraphy, CT-scan, and MRI. In fact, the MRI is widely used and provides better information for early detection of osteomyelitis than other imaging modalities. It can detect necrotic bone, sinus tracts, and even abscesses. We look for soft tissue swelling, cortical bone loss, active bone resorption and remodeling, and periosteal reaction. Oftentimes, plain radiography and MRI are used in combination. Treatment:Treatment of osteomyelitis actually is a teamwork effort among various medical professionals, including the primary care provider, the radiologist, the vascular, the pharmacist, the podiatrist, an infectious disease specialist, orthopedic surgeons, and the wound care team.Something to take into consideration, if the patient is hemodynamically stable it is highly recommended to delay empirical antibiotic treatment 48-72 hours until a bone biopsy is obtained. The reason is that with percutaneous biopsy ideally done before the initiation of antibiotic treatment, “the microbiological yield will be higher”.We'll have a better idea of what particular bugs are causing the problem and guide the treatment appropriately. The choice of antibiotic therapy is strongly determined by susceptibilities results. The antibiotic given will be narrowed down only for the targeted susceptible organisms. In the absence of such information, or when a hospitalized patient presents with an increased risk for MRSA infection, empiric antibiotic coverage is then administered while awaiting culture results. It should be broad-spectrum antibiotics and include coverage for MRSA, broad gram-negative and anaerobic bacteria. For example, vancomycin plus piperacillin-tazobactam, or with broad-spectrum cephalosporin plus clindamycin. Treatment will typically be given for 4 to 6 weeks.The duration between 4-6 weeks is important for complete healing, but a small study with a small sample showed that an even shorter duration of 3 weeks may be effective, but more research is needed. In certain situations, surgery is necessary to preserve viable tissue and prevent recurrent infection, especially when there are deep abscesses, necrosis, or gangrene, amputation or debridement is deemed appropriate. If the infected bone is completely removed, patients may need a shorter course of antibiotics, even a few days only. Amputation can be very distressing, especially when we need to remove large pieces of infected bone, for example, a below-the-knee amputation. We need to be sensitive to the patient's feelings and make a shared decision about the best treatment for them.In patients with diabetes, additional care must be taken seriously, patient education about the need for compliance with treatment recommendations, with careful wound care, and good glycemic control are all beneficial for the healing and recovery process. Because this is a very common problem in the clinic and at the hospital, we must keep our eyes wide open and carefully assess patients with suspected osteomyelitis to detect it promptly and start appropriate treatment. Adequate and timely treatment is linked to fewer complications and better outcomes._________________________Conclusion: Now we conclude episode number 173, “Acute Osteomyelitis.” Future Dr. Tran explained the pathophysiology, diagnosis, and management of osteomyelitis. A bone biopsy is the ideal method of diagnosis. Delaying antibiotic treatment a few days until you get a biopsy is allowed if the patient is stable, but if the patient is unstable, antibiotics must be started promptly. Dr. Arreaza mentioned the implications of amputation and that we must discuss this treatment empathically with our patients. This week we thank Hector Arreaza and Di Tran. Audio editing by Adrianne Silva.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Bury DC, Rogers TS, Dickman MM. Osteomyelitis: Diagnosis and Treatment. Am Fam Physician. 2021 Oct 1;104(4):395-402. PMID: 34652112.Cunha BA. Osteomyelitis in elderly patients. Clin Infect Dis. 2002 Aug 1;35(3):287-93. doi: 10.1086/341417. Epub 2002 Jul 11. PMID: 12115094.Fritz JM, McDonald JR. Osteomyelitis: approach to diagnosis and treatment. Phys Sportsmed. 2008 Dec;36(1):nihpa116823. doi: 10.3810/psm.2008.12.11. PMID: 19652694; PMCID: PMC2696389.Hatzenbuehler J, Pulling TJ. Diagnosis and management of osteomyelitis. Am Fam Physician. 2011 Nov 1;84(9):1027-33. PMID: 22046943.Hofstee MI, Muthukrishnan G, Atkins GJ, Riool M, Thompson K, Morgenstern M, Stoddart MJ, Richards RG, Zaat SAJ, Moriarty TF. Current Concepts of Osteomyelitis: From Pathologic Mechanisms to Advanced Research Methods. Am J Pathol. 2020 Jun;190(6):1151-1163. doi: 10.1016/j.ajpath.2020.02.007. Epub 2020 Mar 16. PMID: 32194053.Momodu II, Savaliya V. Osteomyelitis. [Updated 2023 May 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK532250/Royalty-free music used for this episode: Trap Chiller by Gushito, downloaded on Nov 06, 2023, from https://www.videvo.net
So many amazing Canna-people, so little time. CannMed 24 was sublime! Here are the another batch of clips we got!Ben Cameransi – Mingowood Pharmacal, LLC - Dr. Benjamin Cameransi, MD, DABA is a Board-Certified Anesthesiologist, with a extensive background in pain management. He has started four Biotech Companies. He was involved in the development of Ryanodex™, a treatment for Malignant Hyperthermia. But wait, there's more… Acidic cannabinoids aren't very stable when they are extracted and purified. Dr. Camersani's team at Mingowood Pharmacal has a way to fix that.Taz Turner -CordovaCann Corp - Taz has the top three attributes we look for in a guest. He knows where Manitoba is located. He's a finance guy who spoke intelligently during his Capital Markets Panel. He is fun to chat to at a breakfast information session. Taz tells us how it is surprisingly difficult to get investment into the cannabis space in 2024. But, numbers and valuation guys like him (who also speak cannabis) are slowly convincing others that opportunities abound.Melissa Moore - Professor, Cannabis Horticulture & Biology, SUNY Niagara Community College. Melissa Moore developed some of her horticultural chops in Northern California, but now passes on her knowledge in Buffalo, NY. She was very helpful getting pics of Trevor during his Capital Markets Panel and then she sparked some intense Aspergillus discussions. Professor Moore tells us why cleanliness is next to godliness in your grow room and, hear why Kirk is frothing at the mouth to pick her brain about how to grow plants better.Ben Cameransi - LinkedInMingowood Pharmacal, LLC - WebsiteTaz Turner -LinkedInCordovaCann Corp. - websiteMelissa Moore - LinkedInSUNY Niagara Horticultural Cannabis Classes - websiteMusic by:Stills-Young Band - Midnight on the Bay -YouTubeAdditional Music:Desiree Dorion desireedorion.comMarc Clement - FacebookTranscripts, papers and so much more at: reefermed.ca
Doctor Theodore Yates visits a patient, grasping at straws to try and find the origin of the Rot—a mysterious illness that is plaguing his town.Find us on Tumblr @TheIchorousRotPod to find out more, or visit our website: https://theichorousrotpod.carrd.co/. Transcripts available at: https://drive.google.com/drive/folders/1oaM9LM7AfqWZ3e-8a7dgvuUgkY7PPrkZ Find all of the Podcast Jam pilots here: https://shows.acast.com/podcast-jamThis episode features Charlie Hyde as Theodore Yates, Grimm Blorbeaux as Alonzo, Niall Rowan as John Marsh, and Moookar as Penelope Pembroke. It was written by Sam Coy and edited by Charlie Hyde, with music by Grimm Blorbeaux.Content warnings: Discussion of death, illness, detailed description of injury. Hosted on Acast. See acast.com/privacy for more information.
In this podcast, we're going to talk about some of the side effects of consuming too much sugar. Some of the well-known side effects of sugar include fatigue, brain fog, belly fat, carb cravings, and cavities. Is there a difference between sugar and carbohydrates? A carbohydrate consists of sugar, fiber, and starch. Starches are called polysaccharides, meaning many sugars or multiple sugar molecules connected together. Starches raise blood sugar levels significantly more than sugar. Starches like maltodextrin, modified food starch, and modified corn starch have a much higher glycemic index than sugar. Here are 7 surprising signs that you're consuming too much sugar: 7. Reduced collagen Reduced collagen will result in loose, wrinkled skin and premature aging. 6. Chronic white tongue Candida from too much sugar will cause you to have a white tongue. You won't be able to get rid of it without eliminating sugar from the diet. 5. Chronic sinus problems Most chronic sinus problems are caused by a fungus called Aspergillus that feeds on sugar. 4. Red or pink gums Red or pink on your toothbrush after brushing could signify a mild case of scurvy or vitamin C deficiency. High sugar consumption blocks vitamin C. 3. Low testosterone Low testosterone can cause erectile dysfunction, decreased libido, and difficulty building muscle. 2. Susceptibility to infection Too much sugar can weaken your immune system, making you more vulnerable to infection. 1. High adrenaline levels Too much sugar damages the cell's ability to make energy in the mitochondria. To compensate, the body produces more adrenaline.
Chronic sinus infections can be frustrating and uncomfortable. While many people turn to antibiotics for relief, they may not realize that these medications only target bacteria and can worsen the situation if the infection is fungal. Fungal infections can be even more problematic, particularly those caused by the invasive fungus Aspergillus. This fungus can break down the lining of your sinus cavities and potentially damage bone and tissue in other areas. It also thrives in environments with oxygen and moisture. If you have a weakened immune system due to conditions such as diabetes, HIV, or a poor diet high in sugar and refined carbs, Aspergillus can take advantage and cause further harm. In fact, it has been known to target and downgrade vitamin D receptors in the body, leading to a compromised immune system. To combat this fungal issue, you can try incorporating natural remedies into your routine. One powerful remedy is garlic oil, which has been shown to inhibit the growth of fungus and bacteria. Oregano oil is also effective in fighting bacteria, yeast, and mold. Both can be diluted with coconut oil which contains compounds that boost the immune system and have anti-fungal properties. Add 5 drops of garlic oil and 5 drops of oregano oil to one teaspoon. Then, add just enough coconut oil until you have one full teaspoon of this mixture. Consider taking this daily for one month to allow it to gradually balance out your body's microorganisms. You can also include xylitol, curcumin, or aloe vera for added benefits. Blue light therapy may also be beneficial, as well as red light therapy if you've had surgery on your sinuses. DATA: https://turnontheblue.com/safe-blue-l...
I'm often asked whether or not there is a correlation between breast implants and mold toxicity. This is a topic that sparks considerable interest and concern among patients, as they seek to understand any possible implications for their health and well-being given the prevalence of mold-related health issues and the widespread use of breast implants. In this episode, we aim to raise awareness and address such inquiries with clarity and accuracy, drawing upon both scientific evidence and clinical experience to provide informed insights and guidance to my patients. Mold toxicity and Breast Implant Illness There's considerable evidence suggesting a connection between high mold toxicity and breast implant illness in women. Through extensive testing, it's been found that around six of thousands of tested samples have shown the presence of fungi, which includes mold. When I look at the numbers, it's clear that the instances of confirmed mold presence in breast implant illness cases are extremely low. Typically, there's a specific explanation for these cases, like one patient who was a triathlete and likely picked up mold during swimming competitions. It's crucial to recognize that water harbors various bacteria, fungi, and viruses, contributing to these isolated incidents. However, in my extensive experience working with patients who have breast implants, I've observed that mold exposure is often tied to environmental factors such as air or food contamination. For example, Aspergillus, a prevalent type of black mold, presents a significant risk. This mold can thrive in various environments, including damp areas in homes or buildings, and can contaminate food sources if proper storage and handling practices are not followed. Additionally, mold tends to grow more in certain weather conditions or times of the year, so patients need to be aware of possible exposure risks. While there are rare cases of mold directly in breast implants, the main focus should be on tackling environmental sources of mold to lower health risks for patients with implants. Food and Wine Safety, Including Ochratoxin and Mold in Coffee and Grains When it comes to items like food and wine, it's important to be aware of the presence of ochratoxin, a type of mold toxin commonly found in wine worldwide. While the European Union has strict guidelines regulating ochratoxin levels in wine, the same standards aren't in place in the United States. This means consumers need to exercise caution, particularly when it comes to wine consumption. Choosing wines labeled as dry farm or organic can provide a more reliable option, particularly for individuals particularly sensitive to mold toxins. Dry farming techniques involve cultivating grapes without irrigation, relying solely on natural rainfall, which can reduce the risk of mold growth compared to grapes grown using conventional methods. Coffee production similarly poses a risk of mold contamination, so it's important to look for mold-free options. Brands like Bulletproof Coffee, founded by Dave Asprey, have gained popularity for focusing on providing mold-free coffee products. Being mindful of mold contamination in various food items, including grains and cereals, is essential for maintaining overall health and minimizing exposure to mold toxins. Breast Implant Illness, Toxicity Testing, and Detoxification Protocols The occurrence of mold exposure stems from a combination of factors, as I've observed in many of my patients and personally experienced living in Austin, where severe winter weather and inadequate home infrastructure can lead to water leaks and mold growth. Given these risks, I advise individuals who are particularly sensitive to mold to consider investing in air filters. However, when considering these various options, it's crucial to ensure they can effectively filter mold spores, which are smaller than bacteria, to safeguard against health issues. This is particularly important for individuals who may have genetic variations impacting their detoxification pathways, as they may be more susceptible to the adverse effects of mold exposure. Beyond simply filtering out mold spores, it's also essential to consider the overall air quality within the home. Factors such as humidity levels, ventilation, and the presence of other pollutants can all contribute to the proliferation of mold and impact indoor air quality. As a plastic surgeon who focuses on breast implant illness, my team and I are experienced in understanding the genetic factors and toxicities that affect our patients. We conduct urine toxicity tests and utilize glutathione challenges to assess their problems and tailor treatment plans accordingly. By focusing on improving the quality of fluid, food, and air intake, we aim to reduce inflammation, which we know correlates with symptom improvement. Addressing mold exposure requires personalized protocols based on toxicity testing results and individual tolerance levels. Given the prevalence of sensitivity among our patients, careful consideration and tailored detoxification strategies are essential for managing their health effectively.
Wednesday - January 3, 2024In the first half, Dr. Joel Wallach discussed the human body's ability to achieve natural healing with the benefits of remedies and supplements that aid in the recovery from chronic conditions. Historically, human societies got minerals from glacial melt that irrigated their fields, and wood and coal ashes from their cooking, but with the advent of electricity, that all changed, and now people have deficiencies which open them up to various ailments and diseases, he argued. To combat various bacteria and infections, he mentioned that he consumes drops of colloidal silver.Wallach cautioned against eating peanut butter or peanuts. Peanuts are grown in the ground and are often infested with a fungus called Aspergillus that produces a toxin associated with liver cancer, he stated. He also believes that it's important to avoid eating various grains like wheat because they contain gluten, which he says destroys the lining of the intestine and prevents food absorption. "Gluten has killed more people than bullets," he declared. Wallach also described placing liquid minerals directly on the body, which can be absorbed through the skin and have beneficial effects.------------In the latter half, publisher of Mysterious World books, Doug Elwell shared his research on ancient references to Planet X and why he believes the planet is the harbinger of epic change. According to Elwell, there is evidence that the Star of Bethlehem was really Planet X, that it comes toward Earth around every 2,000 years, and that it has been associated with ancient cataclysms. We could see the return of Planet X in our lifetimes, possibly in the next few years, he continued. In his interpretation, Planet X's orbital characteristics are central to different parts of the Bible and to the Book of Revelation, in particular, which he said indicates that Planet X will eventually replace Earth as the new home for humanity.Elwell talked about an ancient race of giants that interbred with humanity before and after the great flood. While the Nephilim were terrestrial, there is evidence that they may have engaged in space travel, he suggested. He also delved into mysteries and riddles of the Sphinx, and said one of the ancient tribes of Israel, Gad, dug into the Sphinx looking for a secret chamber (similar to what Edgar Cayce had said about a Hall of Records being hidden there). Elwell interpreted a passage in Deuteronomy as being about the Sphinx, and that the Gad found an ancient stone known as the 'Lawgiver' there, which could be used to communicate directly with God. This object was like a proto Ark of the Covenant, he added. --- Send in a voice message: https://podcasters.spotify.com/pod/show/georgenoory/message
Wednesday - January 3, 2024In the first half, Dr. Joel Wallach discussed the human body's ability to achieve natural healing with the benefits of remedies and supplements that aid in the recovery from chronic conditions. Historically, human societies got minerals from glacial melt that irrigated their fields, and wood and coal ashes from their cooking, but with the advent of electricity, that all changed, and now people have deficiencies which open them up to various ailments and diseases, he argued. To combat various bacteria and infections, he mentioned that he consumes drops of colloidal silver.Wallach cautioned against eating peanut butter or peanuts. Peanuts are grown in the ground and are often infested with a fungus called Aspergillus that produces a toxin associated with liver cancer, he stated. He also believes that it's important to avoid eating various grains like wheat because they contain gluten, which he says destroys the lining of the intestine and prevents food absorption. "Gluten has killed more people than bullets," he declared. Wallach also described placing liquid minerals directly on the body, which can be absorbed through the skin and have beneficial effects.------------In the latter half, publisher of Mysterious World books, Doug Elwell shared his research on ancient references to Planet X and why he believes the planet is the harbinger of epic change. According to Elwell, there is evidence that the Star of Bethlehem was really Planet X, that it comes toward Earth around every 2,000 years, and that it has been associated with ancient cataclysms. We could see the return of Planet X in our lifetimes, possibly in the next few years, he continued. In his interpretation, Planet X's orbital characteristics are central to different parts of the Bible and to the Book of Revelation, in particular, which he said indicates that Planet X will eventually replace Earth as the new home for humanity.Elwell talked about an ancient race of giants that interbred with humanity before and after the great flood. While the Nephilim were terrestrial, there is evidence that they may have engaged in space travel, he suggested. He also delved into mysteries and riddles of the Sphinx, and said one of the ancient tribes of Israel, Gad, dug into the Sphinx looking for a secret chamber (similar to what Edgar Cayce had said about a Hall of Records being hidden there). Elwell interpreted a passage in Deuteronomy as being about the Sphinx, and that the Gad found an ancient stone known as the 'Lawgiver' there, which could be used to communicate directly with God. This object was like a proto Ark of the Covenant, he added. --- Send in a voice message: https://podcasters.spotify.com/pod/show/georgenoory/message
Wednesday - January 3, 2024In the first half, Dr. Joel Wallach discussed the human body's ability to achieve natural healing with the benefits of remedies and supplements that aid in the recovery from chronic conditions. Historically, human societies got minerals from glacial melt that irrigated their fields, and wood and coal ashes from their cooking, but with the advent of electricity, that all changed, and now people have deficiencies which open them up to various ailments and diseases, he argued. To combat various bacteria and infections, he mentioned that he consumes drops of colloidal silver.Wallach cautioned against eating peanut butter or peanuts. Peanuts are grown in the ground and are often infested with a fungus called Aspergillus that produces a toxin associated with liver cancer, he stated. He also believes that it's important to avoid eating various grains like wheat because they contain gluten, which he says destroys the lining of the intestine and prevents food absorption. "Gluten has killed more people than bullets," he declared. Wallach also described placing liquid minerals directly on the body, which can be absorbed through the skin and have beneficial effects.------------In the latter half, publisher of Mysterious World books, Doug Elwell shared his research on ancient references to Planet X and why he believes the planet is the harbinger of epic change. According to Elwell, there is evidence that the Star of Bethlehem was really Planet X, that it comes toward Earth around every 2,000 years, and that it has been associated with ancient cataclysms. We could see the return of Planet X in our lifetimes, possibly in the next few years, he continued. In his interpretation, Planet X's orbital characteristics are central to different parts of the Bible and to the Book of Revelation, in particular, which he said indicates that Planet X will eventually replace Earth as the new home for humanity.Elwell talked about an ancient race of giants that interbred with humanity before and after the great flood. While the Nephilim were terrestrial, there is evidence that they may have engaged in space travel, he suggested. He also delved into mysteries and riddles of the Sphinx, and said one of the ancient tribes of Israel, Gad, dug into the Sphinx looking for a secret chamber (similar to what Edgar Cayce had said about a Hall of Records being hidden there). Elwell interpreted a passage in Deuteronomy as being about the Sphinx, and that the Gad found an ancient stone known as the 'Lawgiver' there, which could be used to communicate directly with God. This object was like a proto Ark of the Covenant, he added. --- Send in a voice message: https://podcasters.spotify.com/pod/show/georgenoory/message
Wednesday - January 3, 2024In the first half, Dr. Joel Wallach discussed the human body's ability to achieve natural healing with the benefits of remedies and supplements that aid in the recovery from chronic conditions. Historically, human societies got minerals from glacial melt that irrigated their fields, and wood and coal ashes from their cooking, but with the advent of electricity, that all changed, and now people have deficiencies which open them up to various ailments and diseases, he argued. To combat various bacteria and infections, he mentioned that he consumes drops of colloidal silver.Wallach cautioned against eating peanut butter or peanuts. Peanuts are grown in the ground and are often infested with a fungus called Aspergillus that produces a toxin associated with liver cancer, he stated. He also believes that it's important to avoid eating various grains like wheat because they contain gluten, which he says destroys the lining of the intestine and prevents food absorption. "Gluten has killed more people than bullets," he declared. Wallach also described placing liquid minerals directly on the body, which can be absorbed through the skin and have beneficial effects.------------In the latter half, publisher of Mysterious World books, Doug Elwell shared his research on ancient references to Planet X and why he believes the planet is the harbinger of epic change. According to Elwell, there is evidence that the Star of Bethlehem was really Planet X, that it comes toward Earth around every 2,000 years, and that it has been associated with ancient cataclysms. We could see the return of Planet X in our lifetimes, possibly in the next few years, he continued. In his interpretation, Planet X's orbital characteristics are central to different parts of the Bible and to the Book of Revelation, in particular, which he said indicates that Planet X will eventually replace Earth as the new home for humanity.Elwell talked about an ancient race of giants that interbred with humanity before and after the great flood. While the Nephilim were terrestrial, there is evidence that they may have engaged in space travel, he suggested. He also delved into mysteries and riddles of the Sphinx, and said one of the ancient tribes of Israel, Gad, dug into the Sphinx looking for a secret chamber (similar to what Edgar Cayce had said about a Hall of Records being hidden there). Elwell interpreted a passage in Deuteronomy as being about the Sphinx, and that the Gad found an ancient stone known as the 'Lawgiver' there, which could be used to communicate directly with God. This object was like a proto Ark of the Covenant, he added. --- Send in a voice message: https://podcasters.spotify.com/pod/show/georgenoory/message
“I collect spores, molds and fungus” - Dr. Egon Spengler Dr. Ilan Schwartz MD PhD (@GermHunterMD) teaches us that we should always at least consider fungi in the differential diagnosis of unexplained sepsis, especially in patients with impaired immune systems or complex medical or surgical histories, and walks us through an approach to antifungals. Be sure to check out the Mycoses Study Group Education & Research Consortium (@MSG_ERC), an organization of clinicians who are dedicated to advancing diagnostics and treatment of fungal disease (where Dr. Schwartz serves on the board of directors!) Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments Intro Rapid fire questions, get to know our guest Intentionally vague case; When should we be worried about fungal infection? Overnight emergencies: Candidiasis and mucormycosis Starting empiric anti-fungals Testing basics: direct versus indirect Fungemia, fungal endocarditis Resistant candida; candida auris Pneumocystis jiroveci pneumonia Outro Credits Producer, Writer, Show Notes, Infographic/Cover Art: Beth Garbitelli MD Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP, Beth Garbitelli MD Reviewer: Emi Okamoto MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Ilan Schwartz MD, PhD Sponsor: Uncommon Goods To get 15% off your next gift, go to uncommongoods.com/CURB. Sponsor: NetSuite Go to NetSuite.com/CURBSIDERS to get your own KPI Checklist. Sponsor: Locumstory Get a comprehensive view of locums at locumstory.com.
Dr. Aliyah Baluch, Program Lead for Bone Marrow Transplant Infectious Diseases at Moffitt Cancer Center and Research Institute, reviews Important opportunistic fungal pathogens of relevance to the stem cell transplant and immunocompromised patient. Dr. Baluch beings by discussing the pharmacologic options for aspergillus treatment and their individual mechanisms of action. Next, through a case-based format, she reviews specific scenarios related to fungal infections with Aspergillus, Mucor, and Sporothrix. Lastly, new agents in the antifungal pipeline are discussed, and a robust question and answer session closes the presentation.
Some people in the cannabis industry are questioning whether it is appropriate or necessary to test inhaled cannabis products for pathogenic Aspergillus. Full disclosure, we at Medicinal Genomics sell qPCR testing kits designed to detect pathogenic Aspergillus on cannabis products. We have also published several resources on our website that describe the potential harms that can be caused by inhaling pathogenic Aspergillus spores and cite with more than 2 dozen Aspergilosis cases in cannabis users. We have also recommended that states that are considering cannabis testing regulations adopt pathogenic Aspergillus testing. Not because we sell Aspergillus tests, but because we want to protect patients. By almost any measure, cannabis is one of the most safe and effective medicines available. And in many cases, the potential harms that can come from using cannabis are not caused by the plant, but rather contaminants. And although cases are rare, The documented cases describing Aspergillosis deaths from contaminated cannabis vastly outnumber the published clinical risks for every other contaminant for which the cannabis industry tests. There are no documented deaths for cannabis-derived heavy metals, mycotoxins, pesticides or incorrect cannabinoid labeling. The same cannot be said So that is our position, but of course we acknowledge that we are biased, and we are not experts on pathogenic fungi; however, our guest today is. David W. Denning is a Professor of Infectious Diseases in Global Health at the University of Manchester in the United Kingdom. He was the founding president, executive director, and CEO of Global Action For Fungal Infections, an organization dedicated to reducing the worldwide burden of fungal disease. In 2016, he became the director of the National Aspergillosis Centre in Manchester, which treats patients with chronic pulmonary aspergillosis (CPA), and led the committee that developed the first CPA guidelines. He chairs the editorial board of a website which focusses on aspergillus and he leads an organisation which provides education on fungal diseases. In short, Dr. Denning is the leading authority on all things Aspergillus, and we asked him many of the questions that have been debated on social media recently, including: Should cannabis be tested for pathogenic Aspergillus Should there be an allowable limit for pathogenic Aspergillus? Is Apergillosis only a concern for immunocompromised patients? Are the number of Aspergillosis cases under reported? How difficult is Aspergillosis to diagnose and treat? How ubiquitous is Aspergillus in the air we breathe? and so much more. Thanks to This Episode's Sponsor: Modern Canna Modern Canna is regarded as Florida's first medical cannabis laboratory and one of the most trusted third party testing providers in the United States. The company's mission is to help set the standard for cannabis testing labs worldwide by providing the most accurate and efficient testing services, delivered with a sense of compassion, integrity, and moral obligation; and to attract and attain clients who value quality data that is verifiable, reproducible, and legally defensible. Modern Canna is the only Leafly Certified laboratory in the eastern United States and adheres to the industry's strictest SOPs and quality control standards. Modern Canna offers a wide variety of testing, rapid turnaround times, and consulting services to Florida Medical Marijuana Treatment Centers (MMTC's) and hemp businesses throughout the US. Learn more at moderncanna.com Additional Resources Too Many Mouldy Joints – Marijuana and Chronic Pulmonary Aspergillosis The Aspergillus website https://en.fungaleducation.org/ Submit an Abstract for CannMed 24 Review the Podcast! CannMed Archive CannMed Community Board [Facebook Group]
Berl Oakley and his team are using Aspergillus nidulans to degrade plastic and then using the secondary metabolites to then cure cancer, make antibiotics, statins, antifungals and more to save people's lives. Talk about killing two birds with one stone. Berl Oakley is the Irving Johnson Professor of Molecular and Cellular Biology at the University of Kansas dedicating the last 40+ years to solving the world's biggest problems with fungi. Sign up for our podcast giveaway here. Our next winner will be selected on October 30, 2023 and contacted via email.www.mushroomrevival.comWe are a functional mushroom company and make 100% certified USDA Organic and Vegan mushroom supplements. We are transparent with our lab results, and use actual fruiting bodies aka mushrooms! We provide our supplements in tincture, capsule, powder, and delicious gummy form. Energy (Cordyceps): Need a little pick-me-up before a workout or when you're picking up your kids from school? The Energy Cordyceps is the mushy match for you.Focus (Lion's Mane): Needing a little more focus in your daily life? Lion's Mane is known to be the mushroom for the brain and may support cognitive function.Calm (Reishi): Looking for some tranquility and zen in your life? Reishi will bring you into the zen state of mind you've been searching for.Daily 10 (Mushroom Mix): It's like having 10 bodyguard mushrooms fighting off all those bad guys. This is a good place to start as it contains all of the daily mushies you need. Not sure where to begin? Take our mushroom quiz here.Use code ‘PODTREAT' for a 30% discount.
In this week's issue: Demographic and socioeconomic factors are associated with diagnosis and treatment outcomes of strabismus in children. An Aspergillus-specific lateral-flow device combined with ratiometric analysis diagnosed Aspergillus-induced fungal keratitis with high accuracy. A survey study finds that children who are unable to afford medical care and have public health insurance are most likely to have vision difficulty. In Stargardt disease (ABCA4 retinopathy), a specific genetic variant exhibits milder symptoms, better vision, and primary RPE damage.
This week we welcome Drs. Dwayne Elmore and Bronson Strickland to school us all on aflatoxin. Aflatoxins are produced by a couple of species of fungi in the genus Aspergillus that can appear in a variety of situations, and when ingested can be harmful to the very birds and mammals we cherish. Our expert guests thoroughly explain aflatoxin, practices we can follow to help prevent it, what to do if we discover molded feed, and then offer some feed solutions that can help. Anyone that feeds corn or uses feed based attractants needs to pay attention and be informed. Respect the science and the game we love. Listen, Learn and Be a Responsible Gamekeeper. Show Notes:MSU Deer Lab Support the showStay connected with GameKeepers: Instagram: @mossyoakgamekeepers Facebook: @GameKeepers Twitter: @MOGameKeepers YouTube: @MossyOakGameKeepers Website: https://mossyoakgamekeeper.com/ Subscribe to Gamekeepers Magazine: https://bit.ly/GK_Magazine Buy a Single Issue of Gamekeepers Magazine: https://bit.ly/GK_Single_Issue Join our Newsletters: Field Notes - https://bit.ly/GKField_Notes | The Branch - https://bit.ly/the_branch Have a question for us or a podcast idea? Email us at gamekeepers@mossyoak.com
Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Why we should fear any bioengineered fungus and give fungi research attention, published by emmannaemeka on August 18, 2023 on The Effective Altruism Forum. Someone asked me a question after my talk on climate change and emerging fungal pathogens. The question was, why should we give attention to fungi when we know the risk of bioengineering it can be low. Hence the weight given to viruses and bacteria. I thought through and wondered that it is interesting and the EA community should understand why this should be considered. I think in my opinion we need to take fungi very seriously for so many reasons: What we know that makes fungi pathogen interesting: There are only three known anitifungal drugs against major fungi pathogens which are not very effective. The available antifungals have narrow spectrus and high toxicity, and because of the plasticity of the fungi genome resistance is developed very easily. The seriousness of this issue was brought to fore during the COVID-19 pandemic, a number of secondary infections due to fungi pathogens were reported . The emergence of Azole resistance Aspergillus in Europe and environment is a concern as the mortality due to antibiotics resistance and limited drugs can get up to 100%. There are no vaccines for fungi. Currently, there are no immunotherapy or any vaccine available for any fungal infection. More research and funding is needed. Here is a nice paper that shows how close we are to finding a vaccine against any fungi pathogen. Candida auris the first fungi to have emerged as a result of climate change is a fungal pathogen. This is really interesting because this yeast behaves like bacteria and is naturally resistant to some antifungals. It is difficult to treat and led to the shutting down of hospitals . A Detroit hospital will stop taking patients temporarily as it tries to contain an outbreak of a rare, but potentially deadly and drug-resistant fungus. Find link to this new here. It was first discovered in 2009 and have now been reported in all the continents of the world. The CDC gives reasons why this pathogen is a problem Why is Candida auris a problem? source It causes serious infections. C. auris can cause bloodstream infections and even death, particularly in hospital and nursing home patients with serious medical problems. More than 1 in 3 patients with invasive C. auris infection (for example, an infection that affects the blood, heart, or brain) die. It's often resistant to medicines. Antifungal medicines commonly used to treat Candida infections often don't work for Candida auris. Some C. auris infections have been resistant to all three types of antifungal medicines. It's becoming more common. Although C. auris was just discovered in 2009, it has spread quickly and caused infections in more than a dozen countries. It's difficult to identify. C. auris can be misidentified as other types of fungi unless specialized laboratory technology is used. This misidentification might lead to a patient getting the wrong treatment. It can spread in hospitals and nursing homes. C. auris has caused outbreaks in healthcare facilities and can spread through contact with affected patients and contaminated surfaces or equipment. Good hand hygiene and cleaning in healthcare facilities is important because C. auris can live on surfaces for several weeks 4. Fungi are the only species that have caused the complete extinction of a species. A newspaper reported thus "A deadly fungus that has driven more species to extinction than any other pathogen has spread across Africa unnoticed. Chytrid fungus, Batrachochytrium dendrobatidis, or Bd for short, is a highly infectious fungus that affects frogs, toads, salamanders and other amphibians(Source). Although various diseases, such as white-nose syndrome resulting from the European fungu...
Aspergillus oryzae, or “koji,” received its important status because it lies at the heart of Japanese cuisine.
On episode #33 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/6 – 7/19/23. Host: Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Early antiretroviral therapy not associated with higher cryptococcal Meningitis mortality in people with HIV in high-income countries (CID) Implementing a rapid Antiretroviral therapy program using starter packs for emergency department patients diagnosed with HIV infection (OFID) Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk Penicillin allergy (JAMA) Infectious diseases consultation associated with reduced mortality in gram-negative bacteremia (CID) Positive impact of [18F]FDG-PET/CT on mortality in patients with Staphylococcus aureus Bacteremia explained by immortal time bias (CID) Azithromycin for bacterial watery diarrhea (JID) Periprosthetic joint infection: current clinical challenges (CID) Old World medieval Treponema pallidum complex treponematosis (JID) Clinical Impact of polymerase chain reaction–based Aspergillus and Azole resistance detection in invasive aspergillosis (CID) Superior accuracy of Aspergillus plasma cell-free DNA PCR over serum galactomannan for the diagnosis of invasive aspergillosis (CID) Tafenoquine co-administered with dihydroartemisinin–piperaquine for the radical cure of Plasmodium vivax malaria (The Lancet) Doubling of cyclosporiasis cases partially attributable to a salad kit (CDC) Efficacy and safety of adjunctive corticosteroids in the treatment of severe community-acquired pneumonia (BMC) Music is by Ronald Jenkees
The organic acids test is a simple at-home urine collection test that can give us insight into multiple areas of the metabolism, including: Bacterial and fungal imbalances (Candida, Aspergillus mould, Clostridia bacteria) Antioxidant status (important to age slower, fight infections, detoxify chemicals and heavy metals, and overall health and well-being) Status of various B vitamins and CoQ10 Mitochondrial function and energy production (crucial for the whole body but especially for the brain, digestive system, and detoxification pathways) Neurotransmitter metabolism (e.g. serotonin, dopamine) Oxalates (found in grains and many common fruits and vegetables)Health Consulting (book your free 15-min session with me): https://christianyordanov.com/health-consulting/Organic acids test sample report overview video: https://christianyordanov.com/organic-acids-test/Use this link to get a discount on my Detox Workshop: https://members.christianyordanov.com/detox-workshop?coupon=CM25With 13+ hours of of video content AND a complimentary 45-minute health consultation session with me, you will learn: Why reducing your toxic exposures is critical in today's world (the toxin connection to disease and ill-health) How to reduce your own anxiety about toxins and the process of creating a cleaner environment for your family How to reduce your family's exposures from your indoor air, water, food, and the products you use in the home What kind of diet best supports your body's detoxification system Which supplements you need to use to support detoxification and long-term health Other modalities you can use to enhance toxin excretion (including accumulated body burden of toxic chemicals and metals) Basic EMF protection practices you need to implement as soon as possible Why healthy gut function is essential for optimal detoxification, and how to support you gut health How to cleanse your liver and gallbladder of gallstones (this may transform your health and well-being!) Common gene variants (SNPs) that affect detoxification, inflammation, oxidative stress, and methylation, and how to reduce the risk with diet, supplementation, and lifestyle strategiesGet the course here: https://members.christianyordanov.com/detox-workshop?coupon=CM25
On the show today, we're going to meet some white seahorses. Then we'll find out how fairy circles are made. After that we'll take a look at some backyard fungi that can eat plastic. Before we take a trip to another galaxy and learn about a new planet. And then we meet a Diamantiasaurus. QUIZ QUESTIONS: What colour are white seahorses? How are fairy circles made? What have scientists found that eats polypropylene plastic? What do scientists think planet LP 791 18d has on it? What was the name of the dinosaur who's skull was recently found? BONUS QUIZ QUESTION: What are the names of the fungi that can eat plastic? ANSWERS: White seahorses can come in all different colours, and their colour can even change, depending on their mood and where they live. The fairy circles were made when termites built their nests underground in a circular pattern, which meant plants couldn't grow above the termite chambers. Fungi found in backyards. Volcanoes. Diamantiasaurus. BONUS QUIZ ANSWER: The fungi known as Aspergillus terreus and Engyodontium album.
Este pódcast está destinado exclusivamente a profesionales de la salud. La neumonía adquirida en la comunidad puede ser causada por diversos patógenos, siendo los más comunes los virus respiratorios (COVID-19, virus de la influenza, virus sincitial respiratorio), bacterias como Streptococcus pneumoniae, Haemophilus influenzae y Staphylococcus aures y bacterias atípicas como Mycoplasma pneumoniae y Chlamydophila pneumoniae. En pacientes inmunocomprometidos también puede haber infecciones por hongos como Aspergillus. ¿Cuánto sabe de su diagnóstico y manejo? ¿Cuál es el papel de los esteroides en su tratamiento? Repase el tema con nuestros anfitriones y el invitado de esta semana: Dr. Jorge Mendoza Ramírez. Notas: https://espanol.medscape.com/verarticulo/5910846 Time stamps Introducción... 00:00 Presentación Dr. Jorge Mendoza... 00:40 Recomendaciones de la semana... 02:45 Caso clínico... 4:30 Epidemiología de la neumonía adquirida en la comunidad... 06:25. Neumonía adquirida en la comunidad en tiempos de COVID-19... 07:50 Esteroides en neumonía adquirida en la comunidad... 9:05 Evidencia clínica...12:00 Estudio CAPE COD... 20:23 Cómo usar esteroides en pacientes con neumonía adquirida en la comunidad grave... 23:50 Esteroides e influenza... 28:00
Dr. Don and Professor Ben talk about the risks of repeatedly using a pepper mill over a pot of water. Dr. Don - not risky
Guest: Dr. Marta Cortesão Star Trek: Discovery introduced us to the mycelial network, a subspace superhighway that astromycologist Paul Stamets learns to navigate using a piece of technology called the spore drive. On this episode of Strange New Worlds, Mike speaks to real-life astromycologist Dr. Marta Cortesão about the wonderful world of fungi: their mycorrhizal networks, their ability to survive in space, and how they may be vital partners on long-duration space missions. The Virtual Trek Con version of this podcast: https://www.youtube.com/watch?v=pFkeQy5Jj1c&ab_channel=VirtualTrekCon Marta's book chapter "Fungal Biotechnology in Space: Why and How?": https://link.springer.com/chapter/10.1007/978-3-030-29541-7_18 Marta's paper "Aspergillus niger Spores Are Highly Resistant to Space Radiation": https://www.frontiersin.org/articles/10.3389/fmicb.2020.00560/full Marta's paper "Colony growth and biofilm formation of Aspergillus niger under simulated microgravity": https://www.frontiersin.org/articles/10.3389/fmicb.2022.975763/full Marta's paper "MARSBOx: Fungal and Bacterial Endurance From a Balloon-Flown Analog Mission in the Stratosphere": https://www.frontiersin.org/articles/10.3389/fmicb.2021.601713/full Follow us on Twitter! Strange New Worlds: https://twitter.com/scienceoftrek Mike: https://twitter.com/miquai Marta: https://twitter.com/martacortesao
In today's episode, I'm talking about peanut butter and how to choose the right one. A good peanut butter contains a reservoir of CoQ10, resveratrol, and phytosterols that help with cholesterol metabolism, as well as a whole host of vitamins and minerals. When choosing a peanut butter, I would look for 100% Valencia peanuts and only two ingredients - organic peanuts and sea salt. Valencia peanuts are mostly grown in dry climates, making it difficult for Aspergillus to grow, the fungus that produces the dreaded disease and cancer-promoting aflatoxin. -------- Start accumulating health with the Shake the Sugar guide: ⬇️⬇️⬇️ https://drwholeness.com/stsguide Ask your lifestyle health questions on social media, tag @drwholeness and use #accumulatehealth. -------- Connect with Dr. Matt online:
Today I am joined by Dr. Nematollahi from the University of Arizona. We are covering medical education, coccidioidomycosis and cryptic species of Aspergillus.
This week the fellas chat "The Last Of Us". The HBO show depicts a world overrun by deadly fungi, but experts say the threat is all too real. Fungi can infect and control the brain, killing hundreds of thousands of people annually. The WHO's list of high-risk fungi includes Aspergillus fumigatus, Candida species, and Cryptococcosis neoformans. Cordyceps, the fungus depicted in the show, is real and can change an insect's behavior. Climate change's impact on fungi is also a concern, highlighting the need for more research to understand their potential impact on humans and the environment. Jer went to a medium and took a lil' something something from it. One man wears RayBan smart glasses to record his hallucinations. A baby is born a giant down in Brazil. For WHAT THE HELLTH?! Addicted to drugs or alcohol? No worries! Just grab a piece of skin, edit it with CRISPR, reattach it, and voila! You'll turn your nose up at that bottle of whiskey or that line of coke. Mice experiments were a success and now researchers are seeking FDA approval for human trials. In five years or so, you'll be saying goodbye to your secret stash and hello to addiction-free skin! Who knew the solution was just a small piece of skin away! Join the post-episode conversation over on Discord! https://discord.gg/expeUDN
This week the fellas chat "The Last Of Us". The HBO show depicts a world overrun by deadly fungi, but experts say the threat is all too real. Fungi can infect and control the brain, killing hundreds of thousands of people annually. The WHO's list of high-risk fungi includes Aspergillus fumigatus, Candida species, and Cryptococcosis neoformans. Cordyceps, the fungus depicted in the show, is real and can change an insect's behavior. Climate change's impact on fungi is also a concern, highlighting the need for more research to understand their potential impact on humans and the environment. Jer went to a medium and took a lil' something something from it. One man wears RayBan smart glasses to record his hallucinations. A baby is born a giant down in Brazil. For WHAT THE HELLTH?! Addicted to drugs or alcohol? No worries! Just grab a piece of skin, edit it with CRISPR, reattach it, and voila! You'll turn your nose up at that bottle of whiskey or that line of coke. Mice experiments were a success and now researchers are seeking FDA approval for human trials. In five years or so, you'll be saying goodbye to your secret stash and hello to addiction-free skin! Who knew the solution was just a small piece of skin away! Join the post-episode conversation over on Discord! https://discord.gg/expeUDN
This week, Appalachian State University master's student, Tom Williams, and Director of Fermentation Sciences, Dr. Brett Taubman, join Cade in the lab to discuss their work on using koji to malt barley for brewing beer. The Brü Lab is brought to you by Imperial Yeast who provide brewers with the most viable and fresh yeast on the market. Learn more about what Imperial Yeast has to offer at ImperialYeast.com today. | Read More | Characterization of Unmalted Barley Treated with Aspergillus oryzae
Dr. Don and Professor Ben talk about the risks of moldy maple syrup that has been boiled to make it safe. Dr. Don - risky ☣️ Professor Ben - risky ☣️ Fungi Associated with Pure Maple Syrup Packed at the Minimum Recommended Reheating Temperature1 | Journal of Food Protection Thermal Inactivation of Bacterial Pathogens and Fungal Spores Under Post-Process Contamination Scenarios in Maple Syrup Processing - ProQuest Effect of temperature and water activity on growth and aflatoxin production by Aspergillus flavus and Aspergillus parasiticus on cured meat model systems - ScienceDirect Microorganisms in Foods 5: Characteristics of Microbial Pathogens | SpringerLink The fungus in my maple syrup :Cornell Mushroom Blog Effect of Processing on Aflatoxin | SpringerLink Microbial Contamination in Maple Syrup Pure Maple Syrup Wagner's Sugar Hill Wisconsin Real Maple Syrup | New Hampshire Maple Syrup | Best Pancake Syrup - Ben's Sugar Shack The Sugarhill Gang - Wikipedia
Show Notes In the latest Sake Deep Dive, Andy and Jim take on Japan's national mold, Aspergillus oryzae–the lowly koji-kin. This is less a historical exploration and more a real look at the nitty gritty on this itty bitty ruler of the sake world. CORRECTION: During the episode, Jim mistakenly called Shirokoji Aspergillus luchuensis. That is incorrect. It is Aspergillis kawachii. Aspergillus luchuensis is another name for Aspergillus awamori. Vocabulary from this episode Kikoji - Yellow koji, Aspergillus oryzae. The standard sake strain of koji kin. Koji kin - the actual way to refer to the mold spores that are added to rice to make rice koji. Kurokoji - Black koji, Aspergillus awamori/Aspergillus luchuensis. The standard strain of koji kin for making the Okinawan rice spirit of awamori. Shirokoji - White koji. Aspergillus kawachii. The standard strain of koji kin for making Japan's spirit of shochu. Oddly, a mutated form of Aspergillus awamori. Toko - Literally “floor/bed.” The table where major hand-made koji production happens. Hako - Literally “box.” A box where moderately sized batches of hand-made koji are propagated for temperature control. Futa - Literally “lid.” Smaller boxes for precise, granular temperature control in hand-made koji production. Recommended Sake Andy - 無窮天穏 Mukkyu Tenon Jim - Gokyo Five Yellow Our theme music is from Lotus Lane by The Loyalist - Preconceived Notions Available at https://soundcloud.com/preconceived-notions Under a Creative Commons — Attribution 3.0 Unported— CC BY 3.0 Free Download / Stream: https://bit.ly/lotus-lane Music promoted by Audio Library https://youtu.be/1YVHRMVwwHg
Today on Mushroom Hour we have the privilege of interviewing Professor Vera Meyer from the Technical University of Berlin. Professor Meyer's career has seen her as a visiting scientist to the Imperial College of Science, Technology and Medicine in London (2003) and to the department of Fungal Genetics and Metabolomics at Leiden University in the Netherlands (2005 - 2006). In 2008, Professor Meyer was appointed assistant professor for Molecular Microbiology and Biotechnology at Leiden University, a position she held for three years. Since 2011, she has been professor at the Institute of Biotechnology and head of its department for Applied and Molecular Microbiology at the Technical University of Berlin. Her scientific work in the field of fungal biotechnology has been published in more than 100 publications. Vera also works as a visual artist, using the pseudonym V. meer. She puts a strong emphasis on sculpting and creating objects from chance finds like forest mushrooms, decaying wood and scrap metal. Inspired by her scientific work with fungi in microbiology, she combines these materials in the sense of a found object. Through her artwork, she wants to enhance the awareness for fungi and their potential in biotechnology and for a sustainable bioeconomy in general. TOPICS COVERED: Childhood Fascination with the Invisible Fungal Biotechnology Seeing Fungi as Friends and as Foes Importance of Multi-Disciplinary Approach Open Science Movement Aspergillus niger, Citric Acid and the Origins of Modern Biotechnology Primary and Secondary MetabolismModulating Metabolic Processes of Aspergillus in Making Products Synthetic Biology BioReactor Cultivation & Ecology of a BioReactor Mycelium Materials Building a Mycelium Materials Database Transdisciplinary Collaboration Reconciling Biotechnology with Conservation and the Precautionary Principle EPISODE RESOURCES: Vera Meyer Academic Page @ TU Berlin: https://www.tu.berlin/en/vcard/vera.meyer Vera Meyer Art (V.Meer): https://www.v-meer.de/ Vera Meyer IG: https://instagram.com/v.meer_/ Art Lab Berlin: https://artlaboratory-berlin.org/de/forschung/mind-the-fungi/ TU Berlin - Natural Building Lab: https://www.nbl.berlin/ "Beauty of the Morbid" Article: https://fungalbiolbiotech.biomedcentral.com/articles/10.1186/s40694-016-0028-4 Aspergillus niger: https://en.wikipedia.org/wiki/Aspergillus_niger Fomes fomentarius: https://en.wikipedia.org/wiki/Fomes_fomentarius Macrolepiota procera (AKA Parasol Mushroom): https://en.wikipedia.org/wiki/Macrolepiota_procera
Kennedy Bradley, an epidemiology fellow at the Department of Public Health, Philadelphia, and Sarah Gregory discuss a fatal infection associated with triazole-resistant Aspergillus fumigatus in Pennsylvania.
Welcome to PICU Doc On Call, A Podcast Dedicated to Current and Aspiring Intensivists. I'm Pradip Kamat coming to you from Children's Healthcare of Atlanta/Emory University School of Medicine. Today we are joined by two wonderful clinical pharmacists — Whitney Moore & Stephanie Yasechko. Whitney is a Clinical Pharmacy Specialist at Children's Healthcare of Atlanta. She is on Twitter at @MoorephinRx. Stephanie is a Pediatric Lung Transplant Clinical Pharmacy Specialist at Cincinnati Children's Hospital Medical Center. We are so excited to have you both on today. My name is Rahul Damania and I am a Pediatric Intensivist at Cleveland Clinic Children's Hospital; Welcome to PICU Doc On Call where we focus on all things MED-ED in the PICU. Our podcast focuses on interesting PICU cases & management in the acute care pediatric setting so let's get into our episode: Welcome to our Episode an 18 yo immunocompromised patient with headache & sore throat Here's the case presented by Rahul: An 18-year-old female (40 kg) with PMH significant for fibrolamellar carcinoma of the liver, presents to the ED with headache and sore throat. She is febrile to 38.3, tachycardic, tachypneic, and has a WBC of 27K on her CBC. She is markedly hypotensive with BP on the arrival of 99/65. Cultures were drawn, the patient was given x1 doses of vancomycin and meropenem, and she was transported to the PICU for further workup and management. Due to her progressive hemodynamic instability, increased inflammatory markers, and marked immunocompromised state, the team is considering broadening her anti-microbial coverage. To summarize key elements from this case, this patient has: Fibrolamellar carcinoma of the liver A presentation of headache, sore throat, and hemodynamic instability with concern for sepsis A current regimen of just antibacterials, which brings up the consideration of adding anti-fungal coverage in her clinically ill state. Our episode today will be covering anti-fungal agents in the PICU. We will review general mycology, understand different classes of antifungals, and highlight practical clinical pearls in the acute care setting. As mentioned, this patient has risk factors for an immunocompromised state due to her underlying liver condition. As we dive deeper into antifungals, Whitney, can you please give us an overview of common fungal pathogens in the PICU? Before we discuss the major drugs, it's important that we take some time to briefly review the most common fungi we encounter clinically since it's hard to choose the right agent when you don't know exactly what you are treating. Clinically, Candida is probably the most common fungal pathogen encountered, especially in warm, moist environments. It is important to determine what type of species is growing. The three major species known to cause infection are C. albicans, C. glabrata, and C. krusei, but it is important to differentiate these species when identified since they have different resistance patterns. Cryptococcus is another type of fungus that is known to cause meningitis or fungemia, especially in immunocompromised or cirrhotic patients. Both Candida and Cryptococcus are classified as yeast on Gram stain. Treating cryptococcus will require the use of an agent that has good penetration to the CNS. Endemic fungi known as Coccidia, Histoplasma, and Blastomyces are known to cause disseminated infections in immunocompromised hosts; however, each fungus is associated with a different geographic region in the United States. With any type of infection, it is always very important to consider your patients' exposures and recent travel history. And finally, there are two major molds that have the potential to be pathogenic. The first is Aspergillus which is identified via hyphae (tall filaments) on Gram stain well known to cause invasive pulmonary infections in the immunocompromised, specifically those who are neutropenic and/or received a lung transplant.
TWiM discusses citizen science surveillance of drug-resistant Aspergillus in garden soil, and the mechanism of action of a copper dependent antibiotic. Become a patron of TWiM. Links for this episode Fanny Hesse (Microbial Menagerie) Citizen science surveillance of Aspergillus (App Envir Micro) Aspergillum (Wikipedia) DMDC, copper dependent antibiotic (Infect Immun) National Summer Undergraduate Research Project Letters read on TWiM 268 Take the TWiM Listener survey!
Episode 66 - Mold Growth in the Indoor Environment with Dr. Chin YangDr. Chin S. Yang has worked with physicians, public health officials, industrial hygienists, IAQ, and environmental and occupational health scientists on various issues of fungal and bacterial exposures in the indoor environment. He is a pioneer in microbiology testing in the indoor environment. He started an environmental microbiology laboratory that has performed testing for microorganisms in samples collected from indoor and outdoor environments, completed contract R&D projects for companies, legal support, and provided support for US companies, universities and US governmental agencies. He served as staff microbiologist with the US Public Health Service, Division of Federal Occupational Health. While working at the agency, he was trained at the Centers for Disease Control and Prevention (CDC) on the isolation and identification of Legionella bacteria. He has also worked with hospitals on establishing sampling and monitoring programs for Aspergillus and other opportunistic fungi.In this episode, we discuss the various strains of toxic mold, their toxic byproducts, and the current methods used to test for them. New York City Guidelines for Mold Assessment and Remediation: https://bit.ly/3M0BESATranscript: https://bit.ly/3P4LN2C Find us on Linktree, Facebook, Instagram, Twitter, TikTok and YoutubeNeed help navigating your mold injury without breaking the bank? Join our low cost education group: patreon.com/exposingmoldSponsors: Michael Rubino, The Mold Medic and All American Restoration, the first and only mold remediation company in the country specializing in remediating mold for people with underlying health conditions or mold sensitivities. They've quickly become the most recommended remediation company from doctors and mold inspectors nationwide. Pick up your copy of Michael Rubino's book, “The Mold Medic: An Expert's Guide on Mold Remediation, " here: https://amzn.to/3t7wtaUExposing Mold is officially a non-profit! To support our efforts donate here: Support the show
Mycotoxins are carcinogenic compounds that arise from specific fungal infections in various crop plants, with corn and peanut being key examples. In the industrialized world, governments monitor relevant crops carefully, and install strict thresholds for presence of these dangerous compounds. But what about Developing World? Today's podcast interviews Dr. Felicia Wu, Professor at Michigan State University. Dr. Wu has analyzed the risk associated with mycotoxins, and has studied how various technologies mitigate their effects. This is a shocking revelation about world food security, and a hopeful glance into methods of surveillance and new technology to improve global human health. # COLABRATalking Biotech is brought to you by Colabra – an R&D platform that brings your lab's world-changing research together in one shared space. Learn more at https://www.colabra.app/# TALKING BIOTECHTwitter: https://twitter.com/talkingbiotechWebsite: https://www.colabra.app/podcasts/talking-biotech/Instagram: https://www.instagram.com/colabrahqThe Talking Biotech podcast is distinct from Dr. Kevin Folta's teaching and research roles at the University of Florida. The views expressed on the show are those of Dr. Folta and his guests, and do not reflect the opinions of the university or Colabra.
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