Podcasts about AMR

Calling all cooking and baking enthusiasts: This special episode is for you! Hosts Sarah Bowen Shea and Sheila Gencarelli, both avid cooks/bakers, serve up a conversation about four new cookbooks. They discuss standout recipes; baking with a variety of flours; small-batch nut butters; and numerous quick weeknight dinner options. The cookbooks they discuss:Easy Everyday: 100 Recipes and Meal Prep Ideas for Effortless Eats: Jessica MerchantBig Bites: Time to Eat!: Nourishing Family Recipes That Cook in an Hour or Less: Kat AshmoreMorning Baking: Roxana JullapatCooking Fast and Slow: Easy, Comforting, (Mostly) Plant-Based Recipes for Busy People: Natalia RudinFeisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Currex: Use code AMR15 for 15% off at https://currex.com/Tifosi Optics: Use code FEISTY2026 for 20% off at https://tifosioptics.com/

If you're trail-running curious—or just love inspiring athletes—this is the episode for you! Host Sarah Bowen Shea is joined by guest host Corrine Malcolm, co-host of Trail Society podcast, to talk with Stephanie Irving, 64, an avid trail runner running the legendary Western States 100, where she'll be the second oldest female participant; she's also the co-founder of Wild Woman Trail Runs. In this in-person episode recorded just days before the big race, Steph and Corrine detail:-what's so special about WS100-the “magic” of a women's-only running race like Wild Woman-how to stop thinking about age as an impediment-fueling advice for endurance races-the value in going before you're ready—whether in a race or life! Before Steph joins the conversation around 11:55, Corrine sheds light on the history of the Western States race.Feisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Currex: Use code AMR15 for 15% off at https://currex.com/Tifosi Optics: Use code FEISTY2026 for 20% off at https://tifosioptics.com/

Whether you have an upcoming race or are simply under a lot of stress, you owe it to yourself to listen to this insightful episode. Coach Liz Waterstraat, with host Sarah Bowen Shea, discusses Performing Under Pressure: The Science of Doing Your Best When It Matters Most by Hendrie Weisinger and J.P. Pawliw-Fry. Coach Liz shares some important lessons gleaned from the book, such as viewing something as a challenge instead of a crisis—then learning to thrive on a challenge. The hosts talk about the effective strategy of “shrinking” a pressure-filled moment, and how a perceived victory can translate to a real win. Plus, Coach Liz tells a tale of a solo, pre-race psych-session…in a port-a-potty. Good stuff!Feisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Currex: Use code AMR15 for 15% off at https://currex.com/Tifosi Optics: Use code FEISTY2026 for 20% off at https://tifosioptics.com/

Our antibiotics are failing us. In 2025, the UK Government said antibiotic resistance (AMR) contributes to more than 35,000 deaths each year in the UK. Emergency doctors say they are losing patients on a regular basis when they run out of ways to treat them. Antibiotics have saved countless lives, but alongside them, there is another unlikely sounding ally in this fight: viruses, so small that they can attack and kill the bacteria causing these devastating infections. They are called bacteriophages, or phages for short. There are more of them than any other commonly occurring natural entity on the planet. And we could be about to see doctors using them on very ill patients in the UK. The thing is scientists have studied bacteriophages for nearly a century. They are used routinely in other countries, and science journalist Marnie Chesterton, who has been following this story for nearly a decade, asks why, suddenly, is phage all the rage?

ON TODAYS PROGRAM…   LE CLERC MUST DO SOMETHING IN AUSTRIA OR HE WILL BE NUMBER TWO!! MCLAREN SAYS BEING A MERCEDES CUSTOMER TEAM IS A DISADVANTAGE! FORMULA ONE RULES KEEP ON EVOLVING! GASLY'S MONACO PODIUM REINSTATEMENT WAS THE RIGHT THING TO DO AND… FERNANDO LOOKING FORWARD TO THE DAKAR RALLY AND RACING AT LE MANS WITH MAX VERSTAPPEN!!!…   THIS WEEK'S NASIR HAMEED CORNER WE HAVE: A MOMENT IN MOTORSPORTS HISTORY…AN INTERVIEW WITH F1 PHOTOGRAPHER PETER NYGARD AND MORE TRIVIA!!! When the rear wing has to go in your carry-on – a look into the different worlds of logistics at Audi How the logistics division of AUDI AG and the Formula 1 project benefit from each other Dieter Braun, Head of Audi Supply Chain, in discussion with his F1 colleagues Björn Brickwedde and Lars Rolack Logistics as a performance factor in motorsport and a driving force in road car production   More than 20 race weekends, global supply chains, tight time windows, geopolitical tensions, and the constant pressure to get every part to the right place on time: Formula 1 is not only a high-performance technological laboratory but also an extreme test for logistics. Many of the challenges faced by Audi Revolut F1 Team on the racetrack are also familiar to Audi Supply Chain – just on a different scale. A discussion between the logistics experts reveals what both worlds can learn from each other.   Dieter Braun, Head of Audi Supply Chain, sums it up: “If there's one thing we need in the company, it's speed. Not just on the racetrack, but when making decisions.” This is exactly where the key leverage lies: Formula 1 demonstrates what quick decisions, clear responsibilities, and precise preparation can achieve. Logistics as a performance factor In Formula 1, logistics directly determines on-track performance. Anything that isn't at the track on time can't be used. If transportation costs are too high, there's less left in the budget for other areas. Björn Brickwedde, Head of Logistics at Audi Revolut F1 Team in Hinwil, Switzerland, explains: “Any savings we make in logistics can be invested in development and parts.” This is especially true under Formula 1's cost cap. Efficient logistics thus becomes a performance factor. Brickwedde cites specific examples: intelligent strategies for return shipments, minimal spare parts inventory, smart route planning, and determining the most cost-effective location from which to ship update parts or components. “Every expense saved can flow into development – and then into lap times.” Audi Supply Chain, in turn, designs and manages the entire customer order process – from ordering an Audi to delivery to the customer. This complex system involves several thousand suppliers in nearly 60 countries to manage the flow of goods comprising around one million parts per day. Every optimization in this cross-divisional core process creates leeway – whether in terms of costs, capital tied up, or the CO2 footprint. “In our role as conductors, we can contribute hundreds of millions in earnings for the company,” says Braun. One example illustrates the scope: Audi Supply Chain doesn't just orchestrate – it also manages crises and, with experienced employees working as a team, overcomes short-term challenges. Braun describes a situation involving the production of the last Audi Q2 cars. A container with displays that could not be reproduced was on its way from China via Dubai to Germany when war broke out in the Middle East. “The shipping company spontaneously decided to call at a port in India and unload all the containers without consulting us,” says Braun. The goods couldn't be obtained in time via India, so Audi organized a detour via Sri Lanka and Turkey. “The parts arrived half a day before they were needed,” says Braun, “otherwise we wouldn't have been able to finish and deliver 2,000 Q2 cars.” Brickwedde's account of the Formula 1 season opener in Melbourne sounds very similar. “A supplementary shipment for the first race was supposed to fly from Zurich to Dubai – that's exactly when restrictions on global air traffic took effect,” he says, referring to canceled transport routes. Important update parts were held up, just like the freight from other teams. “We organized an alternative route with F1 Cargo and DHL and prepared new customs documents. It was a nerve-wracking ordeal for everyone involved – but the parts arrived in Melbourne on Wednesday evening, and thanks to the great teamwork on site, both cars were fully assembled in time for the first session.” In doing so, the logistics team laid the groundwork for Audi Revolut F1 Team to score its first points right off the bat in its debut in the premier class of motorsport. Speed is also a key factor in the Audi Supply Chain The racing series brings into sharp focus what often remains abstract in mass production: the impact of quick decisions. “In a race, you immediately realize when you've made a wrong strategic decision – for example, when you leave the pit lane too late,” says Braun. “From a business perspective at Audi, the impact of a decision often only becomes apparent later, but it can be just as serious. Deciding too late during a crisis is problematic – but so is doing so during planning, for example with long-term investments, which makes it particularly challenging for my team and the relevant departments.” The Formula 1 involvement provides a tangible narrative for this. Braun uses the Audi R26 as a permanent background image for his meetings – not just out of enthusiasm for motorsport, but as a signal to the organization: speed matters in the supply chain, too. Formula 1 shows that a good solution at the right time is more valuable than a perfect solution that comes too late. When the rear wing has to go in your carry-on The most exciting examples emerge where planning and improvisation meet. Brickwedde talks about the limited availability of parts during race operations: “We manage the production of parts very efficiently. This is partly because of the cost cap, but also because we only take to the racetrack what we genuinely believe we'll need. If something unexpected happens, you've got to think on your feet. This means that a team member might have to carry the necessary components in their luggage so that they're available at the track as quickly as possible. In a pinch, these could even be parts of a rear wing.” Time windows are tight on the power unit side as well. Lars Rolack, Head of Logistics at Audi Formula Racing in Neuburg an der Donau, describes the unscheduled return shipment of a high-voltage battery during the race weekend in Miami: hazardous materials, special customs and transport regulations, a short analysis window in Neuburg – and shipment back out to the next race just a few days later. “The battery arrived at our facility in Neuburg on Monday morning and was shipped out again on Wednesday evening, heading for Montreal.” Even though the processes at Audi Supply Chain are generally more predictable, the combination of foresight and flexibility remains a crucial success factor – for instance, in the face of supply bottlenecks, natural disasters, or geopolitical disruptions, which have almost become the new normal these days. Rolack used to work in the logistics division at AUDI AG himself before moving to the Formula 1 project. “My background in planning and my experience helped me, but race logistics is a very ad-hoc business – we all had to adapt our mindset extremely quickly to the pace.” While Audi's supply chain division manages several thousand different suppliers across the globe using a multitude of processes – now also with the help of complex mathematical algorithms – organizational skills and personal networks are what count in the F1 project. “If something gets stuck here, my first instinct is to pick up the phone. Thanks to lean processes and short lines of communication within the team, problems can be solved very quickly,” says Rolack. Lundgaard Charges From Last to First To Win at Road America ELKHART LAKE, Wis. (Sunday, June 21, 2026) – Christian Lundgaard asked his Arrow McLaren team over the radio what everyone else also wondered after the Dane took the checkered flag Sunday for the XPEL Grand Prix at Road America Presented by AMR. “How did we do that?” Lundgaard asked incredulously to his pit box. SEE: Race Results Lundgaard used strategy, speed and a bit of good fortune to climb from last in the 25-car field after contact on Lap 1 to earn his second victory of the season in the No. 7 Arrow McLaren Chevrolet. The race ended under caution when Graham Rahal spun into the gravel trap outside Canada Corner after contact with Will Power while dueling for third place on a one-lap restart to the checkered flag. The victory was the third of Lundgaard's NTT INDYCAR SERIES career, joining his win in May on the Indianapolis Motor Speedway road course with Arrow McLaren and in 2023 on the streets of Toronto with Rahal Letterman Lanigan Racing. “I knew we had a chance,” Lundgaard said of the probability of winning after the early contact. “I knew how this race panned out last year, and I knew it was all about just sticking in the race. I did that last year. I made a bunch of mistakes last year that spun ourselves around last year, and I just wanted to make up for that. “We've been on the struggle bus all weekend, so to turn this around, I have to thank the team for that.” David Malukas finished second in the No. 12 Verizon Team Penske Chevrolet, his third runner-up finish of the season as he seeks his first career victory. Power held on to finish third in the No. 26 TWG AI Honda, matching his best finish of his first season with Andretti Global. Kyffin Simpson finished a season-best fourth in the No. 8 Sunoco Chip Ganassi Racing Honda, with points leader and four-time series champion Alex Palou rounding out the top five in the No. 10 DHL Chip Ganassi Racing Honda. Lundgaard, who started 12th, took the lead for the second and final time on Lap 52 of the 55-lap race when the No. 66 Meyer Shank Racing w/Curb Agajanian Honda of leader Marcus Armstrong slowed with a mechanical problem. Armstrong led by 2.787 seconds with five laps to go before mechanical fate cruelly robbed him of what may have been his first career victory. Armstrong's stricken machine finally lost power in Turn 5 on Lap 53, triggering a caution period and a one-lap race to the checkered flag. Lundgaard never was challenged by Malukas on the final one-lap trip around the 14-turn, 4.014-mile road course, with most of the attention focused on the fierce duel for third between series veterans Power and Rahal. Power, holding a straight-line speed advantage, attempted to move to the outside of Rahal at the end of the back straightaway, with both cars making contact and Rahal's No. 15 MSC Industrial Supply Honda spinning into the gravel, ending the race. That was the climax to a thrilling race filled with varying tire strategies and fierce competition for nearly every position. But nothing was more exciting or improbable than Lundgaard's charge to the front. On the opening lap, Lundgaard made contact with Scott Dixon in Turn 1, damaging the left front wing on Lundgaard's car and deflating one of his Firestone Firehawk tires. He pulled into the pits on Lap 2 for tires, fuel and a new front wing, with Arrow McLaren strategists devising new tactics on the fly. Lundgaard cycled to the lead for the first time on Lap 43 when Armstrong, Malukas and Rahal made their final pit stops from the top three positions. Danish driver Lundgaard led Rosenqvist by 11.720 seconds on Lap 45 when he made his final pit stop, with the Arrow McLaren team refilling his fuel and fastening four Firestone Firehawk alternate tires in a speedy 7.1 seconds. The big cushion before the stop allowed Lundgaard to exit his final stop second behind Armstrong and just ahead of Malukas, who had hotter, stickier rubber on his wheels and passed Lundgaard for second on Lap 46. Josef Newgarden made his final stop from the lead on Lap 49 in the No. 2 PPG Team Penske Chevrolet, handing the lead back to Armstrong, who was 3.671 seconds ahead of Malukas. Meanwhile, Lundgaard passed Malukas for second on Lap 49, with Armstrong nearly three seconds up the road. Then Armstrong's bid for his first win evaporated as his power dwindled, letting Lundgaard pass for the lead on Lap 52. “It was all smooth sailing,” a deflated Armstrong said. “I came out of Turn 6, and the engine just started sputtering like it was out of fuel. But clearly it wasn't. And then it just completely died. There was no indication there was nothing wrong.” Pole sitter Palou led 13 laps, but his chances for a fourth career Road America victory vanished when he was penalized for speeding in the pits on Lap 29. Palou fell to 22nd after his drive-through penalty on one of the longest pit roads in the series, but he was appointment viewing in his charge toward the front over the closing 25 laps. Palou leads second-place Malukas by 60 points and third-place Kyle Kirkwood, who finished 10th, by 61 points in the standings. Lundgaard is fourth, 77 points behind Palou. The next NTT INDYCAR SERIES event is The Honda Indy 200 at Mid-Ohio Presented by the 2027 CR-V Hybrid on Sunday, July 5 at Mid-Ohio Sports Car Course near Columbus, Ohio.

Anyone headed on a summer vacation or away on a work trip needs to listen to this episode. Hosts Sarah Bowen Shea and Amanda Loudin, plus two other frequent travelers (a triathlete and an ultrarunner/flight attendant!), share advice and anecdotes about exercising while away from familiar stomping grounds. Details include:-been-there, done-that advice on making smart hotel choices-packing pointers-the best apps to get the lay of the land + plan running routes-how to make sure recovery is part of your time away-encouragement to jump into a “destination” raceBefore the host duo transitions to telling tales about their on-the-go workouts around 14:00, Amanda shares about a 41-mile Appalachian Trail hiking event she completed recently.Watch on YouTubeFeisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Currex: Use code AMR15 for 15% off at https://currex.com/Tifosi Optics: Use code FEISTY2026 for 20% off at https://tifosioptics.com/

Feeling like diving into summer with some engaging reads? Listen to this episode in which hosts Sarah Bowen Shea and Ellison Weist jump into two books set in and around water—one is a debut that Ellison quite enjoyed, while the other is a dystopian tale. Ellison has praise for the historical war-and-love story in the episode's mix, while the hosting duo is divided over the new novel by the Pulitzer-prize-winning author of Less and Less Is Lost. Sarah is enamored with the “dear” protagonist and his adventures, while Ellison finds the characters too precious and predictable. The novels they discuss:Under Water: Tara MenonUnderlake: Erin L. McCoyChildren of the Wild: Kevin PowersVilla Coco: Andrew Sean GreerFeisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Currex: Use code AMR15 for 15% off at https://currex.com/Tifosi Optics: Use code FEISTY2026 for 20% off at https://tifosioptics.com/

Let's not kid ourselves: Everyone needs to listen to this episode because extreme weather is coming, if it hasn't arrived already. Hosts Sarah Bowen Shea and Coach Liz Waterstraat (a hot-weather racing warrior!) welcome Christopher Minson, Ph.D., a professor of Human Physiology at University of Oregon, where he is also co-director of the Exercise and Environmental Physiology Labs, to strategize about running and cycling in hot weather. Dr. Chris shares:-some fascinating science re: sweat + thermoregulation-reasons to run outside instead of in a climate-controlled enviro-somewhat-surprising advice for what to wear when running in the heat-the importance of other success-producing factors, like rest + hydration-why your heat training should start mid-winter!Before the heat-expert joins around 10:10, Coach Liz talks about making peace with her family's summer schedule (including her teen son's late-night second dinners).Watch on YouTubeFeisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Currex: Use code AMR15 for 15% off at https://currex.com/Tifosi Optics: Use code FEISTY2026 for 20% off at https://tifosioptics.com/

A single-vehicle rollover near the 18900 block of SE 20th Street at 2:20 a.m. left one person ejected and conscious, with the vehicle's rear suspended above the ground by a tree. Vancouver Fire controlled a natural gas leak while AMR transported the patient for further care. https://www.clarkcountytoday.com/community_news/single-vehicle-rollover-crash-results-in-injury-and-natural-gas-leak/ #VancouverFire #PublicSafety #ClarkCounty #TrafficSafety #NaturalGasLeak #Vancouver #WashingtonState #EmergencyResponse

Anyone feeling rundown or overburdened owes it to herself to listen to this episode about a brand-new book called The Art of Pacing: A Guide to Balancing Short-Term Demands with Long-Term Thriving by Elizabeth Svoboda. A big fan of this 188-page book, Coach Liz Waterstraat details lessons learned from it, including the importance of choosing to rest (couched in the term, “principled dissent”) and why a “struggle phase” when starting a run or kicking off a work project is natural and normal. Discover what it means to “re-story”—and why it can provide clarity and energy.Feisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Currex: Use code AMR15 for 15% off at https://currex.com/Tifosi Optics: Use code FEISTY2026 for 20% off at https://tifosioptics.com/

For every mother worried she might have to forgo athletic goals due to parenting demands, this episode is for you! In this heartwarming, inspiring episode, hosts Sarah Bowen Shea and Tish Hamilton talk with two mothers who were able to pursue their marathon goals thanks, in part, to a generous grant from For All Mothers+. (Psst, the application deadline is June 10!) One momma completed her first marathon, while the other guest qualified for the Olympic Marathon Trials (!). In the episode:-both runners detail how their marathon dreams became reality-one mom's journey from watching the Olympic Marathon Trials on TV to qualifying for them-the importance of the word “and” for women-how running became therapy for a single mom-the sweet finish-line surprise that awaited the first-time marathonerBefore the first guest joins around 12:25, the co-hosts gab about a recent sporty getaway.Watch the episode on YouTubeFeisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/Join AMR at the Grand Traverse in Duluth, MN on October 3rd! Use code AMR20 for $20 off when you register at https://feisty.co/events/the-grand-traverse/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Currex: Use code AMR15 for 15% off at https://currex.com/Tifosi Optics: Use code FEISTY2026 for 20% off at https://tifosioptics.com/

Welcome to this episode of The New Warehouse Podcast, where Kevin Lawton speaks with David Scheffrahn live from MODEX 2026 in Atlanta. Representing Ocado Intelligent Automation(OIA), Scheffrahn shares how the company is combining high-density storage, robotic fulfillment, AI-driven orchestration, and autonomous mobile robots to improve warehouse fulfillment automation. The conversation explores Ocado's storage and retrieval system, its fulfillment software platform Ocado IQ, and a new AMR focused on pallet and case fulfillment. Learn more about our sponsor Dexory's Storage Health here. Follow us on LinkedIn and YouTube.Support the show

Antimicrobial resistance (AMR) is being called the "silent pandemic" by global health experts, but what does that actually mean? In this episode of the Wholistic Living Podcast, we explore why antibiotic-resistant infections are increasing worldwide, how bacteria develop resistance through biofilms and horizontal gene transfer, and why common microbes such as E. coli, Klebsiella, Streptococcus, and Enterococcus are becoming a growing concern. Learn why most colds and flus are viral and do not respond to antibiotics, how repeated antibiotic use can impact the gut microbiome, and what a holistic approach to immune resilience can teach us about preventing infection. We'll discuss the latest antimicrobial resistance statistics, the role of stool testing, and practical ways to support your immune system naturally through nutrition, lifestyle, and gut health.Equip Grass fed protein: www.equipfoods.com/MARLA60 Day Gut Reset ($200 OFF) - https://checkout.teachable.com/secure/1716725/checkout/order_52y48hdz?coupon_code=SECRETOFFER

No matter what speed your forward motion is, you need to listen to this enlightening episode featuring Milica McDowell, DPT, co-author of Walk: Rediscover the Most Natural Way to Boost Your Health and Longevity―One Step at a Time. Along with hosts Sarah Bowen Shea and Molly Williams, Dr. Milica details:the true sweet spot of daily steps (pssst: It's less than 10,000!)the remarkable powers of a 5-minute walk and walking backwardposture tips and walking drillswhy you might want to ditch your weighted vestthe myriad benefits runners can gain by adding walks to their daily routineThe co-hosting duo talk about recent swimming and hiking adventures before Dr. Milica joins around 08:50.Watch on YouTubeJoin AMR at the Grand Traverse in Duluth, MN on October 3rd! Use code AMR20 for $20 off when you register at https://feisty.co/events/the-grand-traverse/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

Anyone who believes limited time, options, or resources are holding them back needs to listen to this intriguing episode. Coach Liz Waterstraat shares surprising lessons learned from the hot-off-the-presses book Inside the Box: How Constraints Make Us Better by David Epstein. Realize why more freedom doesn't equal more possibility—or more productive workouts or better race outcomes! Learn how to minimize distractions during workouts to boost focus. And discover if you are a “satisficer” like Sarah or more of a maximizer/satisficer hybrid like Coach Liz.Join AMR at the Grand Traverse in Duluth, MN on October 3rd! Use code AMR20 for $20 off when you register at https://feisty.co/events/the-grand-traverse/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

20 years ago, automation was a pipe dream for industrial workers, 10 years ago it existed in research and development labs. Now it's fully operational in warehouses, production facilities and even mines.The companies driving robotics forwards are going one step further than developing smarter AI. They're figuring out how to apply that advanced engineering to ‘gritty' manufacturing – and there are few places that understand that world better than the Steel City.Pittsburgh has become an important ecosystem for developing autonomous technologies, the combination of engineering talent and thriving industrial background has turned it into somewhat of a testing ground for physical AI.Recorded in Pittsburgh, Pennsylvania, this was a special live show in collaboration with the Pittsburgh Robotics Network. Chris is joined by three industry leaders to talk about adopting autonomy in critical industries. Brett Phillips is Chief Revenue Officer and General Council at Hellbender, specializing in on-edge AI hardware development. David Griffin is Chief Sales Officer at Seegrid, manufacturer of autonomous mobile robots. Mike Smocer is CEO of Mine Vision Systems, a mining technology company building real-time digital mapping systems for GPS denied environments.They dig into how autonomy is moving beyond one-off projects, and into fully integrated systems. Brett breaks down how the incorporation of sensors and models are shrinking development timelines for autonomous systems and why Pittsburgh's willingness to ‘get their hands dirty' is key. David explains how advances in perception and control systems have pushed AMRs beyond basic pallet moves into large, complex material moves through busy logistics environments. Mike shares how Mine Vision Systems support vital underground decision making with millions of dollars of impact by replacing manual mapping and tribal knowledge with accurate digital records.For anyone considering where robotics and AI can create value inside their operations, thinking about the intersection between advanced software and manufacturing, or curious why Pittsburgh has become so strong in robotics and autonomy, this episode is a look at how three industry leaders are managing that change today.In this episode, find out: • About the technological advances that shifted autonomy from isolated deployments to a broader ecosystem covering manufacturing, logistics, mining and warehouse operations.• How David explains the evolution of AMRs within lifting, going from limited pallet moves to an all-in-one technology capable of moving any material to any location.• Why mid-tier manufacturers are becoming a major driver of autonomy adoption due to labor constraints and the positive impact of this in regional production environments.• What mining looks like without the implementation of automated systems, Mike discusses highly intelligent operators still using coloured pencils and paper to capture critical underground data.• Mining as a tunnel building process with the constant balance of optimizing extraction with breakage vs. how much time and cost is spent processing the material caused by that breakage.• How Hellbender utilizes their expertise and capability to provide an end-to-end service inhouse, getting their customers to market in a matter of months rather than years.• The role of sensors, on-edge AI, and manufacturing capability in accelerating the production of perception systems that serve as the eyes and ears of the autonomy stack.• What the conversation reveals about Pittsburgh's current position as a robotics hub where engineering talent, institutional history and manufacturing culture are allowing them to go head-to-head with the likes of Silicon Valley.Enjoying the show? Please leave us a review here. Even one sentence helps. It's feedback from Manufacturing All-Stars like you that keeps us going!Tweetable Quotes: • “At the end of the day, we are a software company. The hardware component of our product is essentially a near commodity at this point. It's the navigation systems, the safety systems, the perception systems, the control systems.” – David Griffin • ”There is a transformation involved. There's change management involved. There are workflows that if you disrupt them just because your cool technology solved one little problem, broke 12... There's an approach to developing your technology so that it succeeds not only now, but in the future.” – Mike Smocer• “What's gonna separate us moving forward is the ability to sort of mash this really high-level, very technical engineering with real-world manufacturing. That is where, uniquely, Pittsburgh stands alone.” – Brett Phillips Do you want to connect with other leaders that are moving the needle in manufacturing everyday?Then make sure to join us in the Manufacturing Happy Hour Industry Community on LinkedIn.Apprentice has developed the first AI Agent designed specifically for manufacturing, not adapted from a general model. It connects across your full tech stack, keeps an eye on operations 24/7, and helps automate the mission-critical workflows your team is handling manually today. This isn't “set it and forget it” AI. Your team stays in control of every critical decision, because that's how real manufacturing works.Recommended Resources• Pittsburgh Robotics Network, facilitating commercial business growth and economic development opportunities for the Greater Pittsburgh region's robotics, automation, and vision communities• Seegrid, delivering customized AMR solutions that meet the changing needs of today's manufacturing, logistics, and warehousing facilities• Mine Vision Systems, maximizing efficiency and safety in underground mining operations with real-time 3D mapping technology• HELLBENDER Inc., building mission-critical hardware and software infrastructure for AI-driven perception systems in autonomy, robotics, and industrial applicationsConnect with David, Mike, and BrettDavid Griffin | Mike Smocer | Brett PhillipsMake sure to visit http://manufacturinghappyhour.com for detailed show notes and a full list of resources mentioned in this episode. Stay Innovative, Stay Thirsty.

No matter what age you were when you became an athlete, you'll enjoy these insightful conversations with three women who didn't discover their sporty side until their 40s. With hosts Sarah Bowen Shea and Tish Hamilton, they share:their “origin” stories of becoming a runner or triathletethe joy of discovering the power of “dirty therapy” (read: trail running)how one runner cut an hour off her marathon finish timeways becoming an athlete changed how they interact in the worlda hilarious—and apt—analogy between running and tooth brushing!Before the first late-bloomer runner hops on around 14:13, Sarah details a recent humbling walk down a marathon-related Memory Lane.Watch on YouTubeJoin AMR at the Grand Traverse in Duluth, MN on October 3rd! Use code AMR20 for $20 off when you register at https://feisty.co/events/the-grand-traverse/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

If you've been eagerly awaiting the latest from the authors of The Help or The Guncle, this is a don't-miss episode! Host Ellison Weist weighs in on Kathryn Stockett's long-awaited novel, and Sarah Bowen Shea details Steven Rowley's new set-in-Palm-Springs book. Ellison also raves about the latest Oprah's Book Club pick. And Sarah goes wild for a novel adaptation on Netflix! The books discussed:The Calamity Club: Kathryn StockettA Deadly Episode: Anthony HorowitzJohn of John: Douglas StuartTake Me with You: Steven RowleyJoin AMR at the Grand Traverse in Duluth, MN on October 3rd! Use code AMR20 for $20 off when you register at https://feisty.co/events/the-grand-traverse/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

Attention adventure lovers: Give a listen to this episode about the Grand Traverse, a single-day trail event in Duluth, MN, that lets you choose the distance you cover and at what pace you want to go (hiking or running). Coach Dimity McDowell and three 2025 Grand Traverse participants join hosts Sarah Bowen Shea and Coach Liz Waterstraat to share details and highlights of this epic undertaking, including:-the training involved for a one-day hiking or running event-how hiking 21 miles stacks up to running a half-marathon-essential nutrition and hydration strategies for success-the power of companionship on the trail-the awe-inspiring beauty of hard-won vistasSarah shares a story about a recent “nature event” involving a swarm of rogue honeybees before Coach Dimity joins around 14:00.Join AMR at the Grand Traverse in Duluth, MN on October 3rd! Use code AMR20 for $20 off when you register at https://feisty.co/events/the-grand-traverse/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr Watch the Episode on YouTube

This is a must-listen for everyone who needs to get out of their own head and make forward progress. Coach Liz Waterstraat shares wisdom and take-away lessons gleaned from Beyond Belief: The Science-Backed Way to Stop Limiting Yourself and Achieve Breakthrough Results by Nir Eyal with Julie Li. In the conversation with host Sarah Bowen Shea, Coach Liz explains that beliefs aren't facts; the effect anticipation has on physical capabilities; and the importance of stacking small wins. And she drops a scientifically backed shocker about the deleterious effects of hitting snooze!Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr Join AMR at the Grand Traverse in Duluth, MN on October 3rd! Use code AMR20 for $20 off when you register at https://feisty.co/events/the-grand-traverse/Follow us on Instagram: https://www.instagram.com/themotherrunner/

This is a must-listen for parents of sporty kids, anyone struggling with an injury, and folks looking for hard-earned wisdom: Running prodigy/phenom Mary Cain, author of the compelling new memoir This Is Not About Running, talks with hosts Sarah Bowen Shea and Tish Hamilton. Interspersed with the hosts expressing anguish at the harassment she endured, Mary details:her reasons for writing a frank, heart-wrenching memoirthe work she's done to recover from her traumahow coaches should treat young athleteswhat she learned from injury that winning couldn't teach herways to advocate for one's health and well beingBefore Mary joins around 12:15, Tish shares her family's history of jaw-dropping longevity.Watch the episode on YouTubeJoin AMR at the Grand Traverse in Duluth, MN on October 3rd! Use code AMR20 for $20 off when you register at https://feisty.co/events/the-grand-traverse/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

Anyone looking for riveting reads (or audiobooks) need to listen to this episode: Hosts Sarah Bowen Shea and Ellison Weist rave about an incredibly smart, cleverly crafted debut novel; a new novel by a beloved author; a quirky paperback; and the latest brilliant page-turner from a hot writer. Listen all the way through, then dash off to get these books and start reading!Yesteryear: Caro Claire BurkeMore Than Enough: Anna QuindlenThe Road to Tender Hearts: Annie HartnettLondon Falling: Patrick Radden KeefeJoin AMR at the Grand Traverse in Duluth, MN on October 3rd! Use code AMR20 for $20 off when you register at https://feisty.co/events/the-grand-traverse/Follow us on Instagram: https://www.instagram.com/themotherrunner/Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

Dr. Eli Cahan explains how he evolved into both a neonatologist and an accomplished, intrepid journalist, inspired by the likes of Atul Gawande and shaped by experiences during the Covid-19 pandemic. It is a balancing act, rushing between fixed medical facilities and airplanes. “We get to bear witness.”  His stories have covered anti-microbial resistance (AMR) among war fighters. An upcoming piece will cover the weakening of prevention and control over polio and the possibility of the reemergence of polio in America. With each, a focus is shaping opinion in Congress. Polio has become a major biosecurity issue and does indeed command attention in Congress and within the administration. The Pitt is fearless in exposing the problems people experience with American health care. At the same time, most health communications are frayed–what to do?

Anyone curious about doing a HYROX race or looking to diversify her running routine needs to listen to this insightful episode. The guests—a HYROX class instructor (Steph Peters), a cyclist/runner taking on her debut HYROX (Kathryn Taylor), and a marathoner who crushed a HYROX doubles race earlier this year (Jackie Minge)—talk with hosts Sarah Bowen Shea and Britany Williams about:What exactly a HYROX race entailsWhy HYROX is more accessible than you might thinkTheories about why HYROX is exploding in popularityWhy runners have an advantage going into a raceWhy one guest chose a certain podcast host to be her doubles partner!Sarah tells tales of her recent jury duty stint (including stair repeats!) before the HYROX instructor hops on around 12:00.Watch the episode on YouTube: https://youtu.be/8z0ZztmcBGIFollow us on Instagram: https://www.instagram.com/themotherrunner/ Feisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/ Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

Anyone in search of deeper personal connections or improved athletic performance needs to listen to this episode in which Coach Liz Waterstraat delves into Revealing: The Underrated Power of Oversharing by Leslie John. Coach Liz details why sharing thoughts and feelings helps manage the emotional load of striving; how silence sends a message (which prompts a pickleball anecdote from host Sarah Bowen Shea); and how humanizing it is to share. In true Another Mother Runner style, TMI quips abound in this ep!Follow us on Instagram: https://www.instagram.com/themotherrunner/ Feisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/ Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

A must-listen episode if you're looking to add a triathlon to your race calendar or to take on a new distance in triathlon: Kelly O'Mara, co-host of the Feisty Triathlon podcast and former editor-in-chief of Triathlete Magazine, shares expert insights on starting and succeeding in triathlon. In a conversation with hosts Sarah Bowen Shea and Molly Williams, Kelly details:how to morph from being a runner to a triathleteovercoming fears + overwhelm about swimmingrealistic race goals (hint: think process, not outcome)the beauty of being part of a triathlon clubmust-have—and can-skip-for-now—gearBefore Kelly joins around 08:15, Molly and Sarah share family updates. Grab Feisty's free beginner sprint triathlon guide.Follow us on Instagram: https://www.instagram.com/themotherrunner/ Feisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/ Momentous: Use code AMR for up to 35% off your first order at https://www.livemomentous.com/Wahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr

Accurate AST results are the backbone of diagnostic stewardship, yet routine quality control (QC) might be missing subtle shifts that skew your hospital's annual antibiogram. By examining a real-world "silent failure" in daptomycin testing, we explore how lab-driven data is essential to the AMR crisis response and why the human eye—and traditional QC bugs—aren't always enough to catch technical drifts. This session breaks down the importance of LIS rules, alert fatigue, and the future of automated susceptibility testing. Guests: Laurel J. Glaser, M.D., Ph.D. Rebekah Dumm, Ph.D. D(ABMM) Links:  Leveraging patient data to detect systematic shifts in daptomycin susceptibility testing associated with reduced prescribing This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Romney Humphries, Ph.D., D(ABMM) and Elitza (Elli) Theel, Ph.D., D(ABMM).  Visit journals.asm.org/journal/jcm to read articles and/or submit a manuscript. Become an ASM member to receive up to 50% off publishing fees when you publish in JCM or any of the ASM journals. Sign up at asm.org/joinasm.

What can the DNA of Neanderthals, woolly mammoths, and ancient proteins tell us about the future of medicine? In this episode, Professor César de la Fuente sits down to discuss his fascinating research goal: using the power of machines to accelerate discoveries in biology and medicine… This conversation explores: The growing global health threat of antimicrobial resistance (AMR). Why ancient DNA and extinct organisms may hold clues for next-generation antibiotics. The role that AI plays in uncovering the genetic data of extinct organisms. What the future of machine biology could mean for human health. Prof. de la Fuente is Presidential Associate Professor at the University of Pennsylvania, where he leads the Machine Biology Group. He is one of the youngest tenured professors in the history of Penn Medicine. He completed postdoctoral research at MIT and earned his PhD from the University of British Columbia. He is widely recognized for pioneering the first computer-designed antibiotic shown to be effective in animal models, which is an achievement that helped launch the emerging field of AI-driven antibiotic discovery. His lab has since identified more than one million potential antimicrobial compounds through computational biology. In addition, Prof. de la Fuente has delivered over 350 invited lectures worldwide, co-authored an influential book on machine learning for drug discovery, secured multiple patents, and published more than 180 peer-reviewed papers in leading journals, including Cell, Science, Nature Communications, PNAS, and Advanced Materials. You can follow Prof. de la Fuente's latest discoveries and research here!

Antimicrobial resistant gonorrhea is a global public health concern. This episode discusses two articles evaluating two new antibiotics, gepotidacin and zoliflodacin, to treat uncomplicated urogenital gonorrhea. A retrospective study of WHO global gonococcal antimicrobial surveillance program (GASP) 2019-2022 data is also reviewed. View episode transcript and references at www.std.uw.edu.This podcast is dedicated to an STD [sexually transmitted disease] review for health care professionals who are interested in remaining up-to-date on the diagnosis, management, and prevention of STDs and STIs. Editor and host Dr. Meena Ramchandani is an Assistant Professor of Medicine at the University of Washington (UW), Program Director of the UW Infectious Diseases Fellowship Program, and Associate Editor of the National STD Curriculum.  

Feisty Media is proud to welcome Another Mother Runner to the Feisty Media family. Enjoy this bonus crossover AMR episode starring, Selene Yeager!--Calling all 40+ women: This is a must-listen episode! The guest is Selene Yeager, host of the popular menopause-focused podcast called Hit Play Not Pause. Selene is the longtime health and science journalist who co-authored ROAR and Next Level with Dr. Stacy Sims. Along with hosts Sarah Bowen Shea and Tish Hamilton, Selene discusses:why a long run can exacerbate night sweats;the in's and out's of hormone therapy;dietary ways to possibly mitigate menopausal symptoms;realistic, actionable ways to strength train; and,how to keep running through midlife.Selene joins the show around 8:25, after Tish talks about her recent “super-secret marathon” and Sarah shares that a 26.2 isn't going to be part of her 2026. (Psst: This episode kicks off a month of Feisty crossover episodes.)

In this episode, featuring audio from a local live workshop, experts Richard Colgan, MD, and Christopher Smith, MD, explore the burden of complicated urinary tract infection (cUTI) on patients and the healthcare system, highlight advances in the treatment of complicated UTIs, and examine approaches to empiric and definitive antibiotic therapy. Topics covered include: The Burden of cUTI and Antimicrobial Resistance Changes in IDSA Guidelines for cUTI Diagnosing cUTI Selection of Empiric and Definitive Therapy Novel Treatments for cUTI Get access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify. Presenters:  Richard Colgan, MD Professor Emeritus Department of Family and Community Medicine University of Maryland School of Medicine Baltimore, Maryland Christopher Smith, MD Infectious Disease Physician Chase Brexton Healthcare Clinical Assistant Professor Shock Trauma Center, University of Maryland Medical Center Baltimore, Maryland Link to program page: https://bit.ly/3Q4TgDK Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this second deep dive episode, Cherry Lim discusses how complex modelling approaches can translate into practical clinical insights. From counterfactual frameworks to real-world prescribing decisions, she explores how data-driven tools can support clinicians in choosing more effective antibiotic treatments.  Timestamps 00:00 – Introduction 01:03 – Understanding counterfactual frameworks 02:56 – Antibiotic choice and survival 05:08 – Clinical decision dashboards 06:24 – Assumptions in AMR modelling

In the final deep dive, Cherry Lim looks ahead to the future of AMR surveillance. She discusses the role of microbiology labs, the value of imperfect datasets, and how integrating genomics, modelling, and cost-effectiveness could transform global health systems over the next two decades. Timestamps 00:00 – Introduction 01:03 – Investing in diagnostics 02:36 – Routine surveillance data 03:53 – Global versus local AMR data 05:08 – Future health systems

Send us Fan MailAntimicrobial resistance (AMR) can feel like an abstract, far-away crisis until you realize how easily it travels through connected systems and how quietly it can persist when we only watch the “end product.” We talk with Dr. Pankaj Gaonkar about antimicrobial resistance in the U.S. poultry industry, starting with a clear definition of AMR and why it is a pressing global health and economic threat. From there, we dig into the uncomfortable reality that resistance can still be detected even as antimicrobial use declines, and why that “disconnect” matters for veterinarians, producers, and anyone who cares about food systems.A big theme is scale and structure. Modern poultry production is often vertically integrated, moving birds through a coordinated chain from breeder farms and hatcheries to broiler grow-out and processing. That efficiency has a downside: if antimicrobial resistant bacteria emerge at one point, they can move through the system. We also unpack how disease pressure in high-density environments can influence therapeutic decisions, and how older antimicrobial exposure can leave behind residues and resistant organisms that continue to shape selection pressure over time.The heart of our conversation is environmental surveillance and the One Health approach. Monitoring litter, soil, water, and air around poultry houses helps reveal where resistance is maintained and how it moves between “inside” and “outside” the farm. Pankaj explains key tools like metagenomics, qPCR, and culture-based methods, along with the real challenges around cost, standardization, and interpreting results in complex microbial communities. We close with practical roles for veterinarians and producers, and what smarter policy could look like to strengthen AMR monitoring without creating unnecessary burden.If you found this valuable, subscribe for more Veterinary Vertex conversations, share the episode with a colleague, and leave a rating and review on Apple Podcasts or wherever you listen.JAVMA article: https://doi.org/10.2460/javma.25.07.0488INTERESTED IN SUBMITTING YOUR MANUSCRIPT TO JAVMA ®  OR AJVR ® ?JAVMA ® : https://avma.org/JAVMAAuthorsAJVR ® : https://avma.org/AJVRAuthorsFOLLOW US:JAVMA ® :Facebook: Journal of the American Veterinary Medical Association - JAVMA | FacebookInstagram: JAVMA (@avma_javma) • Instagram photos and videosTwitter: JAVMA (@AVMAJAVMA) / Twitter AJVR ® : Facebook: American Journal of Veterinary Research - AJVR | FacebookInstagram: AJVR (@ajvroa) • Instagram photos and videosTwitter: AJVR (@AJVROA) / TwitterJAVMA ®  and AJVR ®  LinkedIn: https://linkedin.com/company/avma-journals

In this first deep dive, Lim explores how routine hospital data and bacterial genomics are transforming our understanding of AMR. She explains how combining datasets and transmission models can uncover hidden pathways of resistance and highlights the challenges of working across diverse healthcare settings.

Cherry Lim joins the EMJ Podcast for a rapid-fire discussion on data, modelling, and antimicrobial resistance. From surveillance gaps to the role of AI, she shares insights into how data is shaping the future of AMR research and policy.

Calling all 40+ women: This is a must-listen episode! The guest is Selene Yeager, host of the popular menopause-focused podcast called Hit Play Not Pause. Selene is the longtime health and science journalist who co-authored ROAR and Next Level with Dr. Stacy Sims. Along with hosts Sarah Bowen Shea and Tish Hamilton, Selene discusses:why a long run can exacerbate night sweats;the in's and out's of hormone therapy;dietary ways to possibly mitigate menopausal symptoms;realistic, actionable ways to strength train; and,how to keep running through midlife.Selene joins the show around 8:25, after Tish talks about her recent “super-secret marathon” and Sarah shares that a 26.2 isn't going to be part of her 2026. (Psst: This episode kicks off a month of Feisty crossover episodes.)Get 20% off, plus free shipping, on all IQBAR products by texting AMR to 64-000Use code AMR for up to 35% off first subscription order at livemomentous.comWahoo Kickr Run: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr The 27th Mile Free Events: Head to https://www.manyhappymiles.com/books for more details and to RSVP.Follow us on Instagram: https://www.instagram.com/themotherrunner/ Feisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/

Midnight Meanderings - Ep 38 SOLO QUEUE DISCORD now available:  https://discord.gg/nXQVqERcSU Show Notes  Welcome to Episode 38! – 2:13         Time to pin you down and force you to listen to what I think of Midnight so far.  Or maybe just entertain you while you work or commute or mow the lawn or whatever it is you are doing.  Thanks for bringing Solo Queue along!  By the way, the countdown checklist idea on a podcast on the day that the U.S. launched four astronauts towards the Moon is sheer coincidence.  In fact, my intro preview came out to Patreon supporters days ago.  Serendipity, baby!   News – 6:37 SQ Socials news Horde neighborhood – Desolate Collective – finally figured out how to add members beyond those on the original charter; not great for momentum, but the key was, as I suspected, strip down to no add-ons and the invite button on the roster actually functioned properly! The test was Gershom and she is the first new member; reach out in game or out if you want to move your Horde house to the Desolate Collective The SQ Guild Solo Together is strong and growing. You can find it in the Alliance Guild Finder, but it is open to both factions.  We have an Alliance side Guild Neighborhood that is open to members of the guild.  If you want to join, just reach out and we will get you an invite, Horde or Alliance.  It is a bunch of cool people of many different backgrounds hanging out, checking in on each other, all very casual.  New Discord link: https://discord.gg/N86fhRkDem  If you are good people, come check it out.  I am @sweeperdave on Discord and of course, soloqueuewow on everything else out there. GT change/delay – yeah, life finds a way into all of my plans; GT on hold, but will return; also quietly on hold is this year's 64-competitor single-elimination tournament among Warcraft characters will take a year off. Rufus is available, Habitat for Humanity; through May 12; The mini war hammer in the mouth is amazing. Music video/marketing from WoW and the musician Aurora is fantastic S1 – what is open, what is left? A lot of S1 is now open with the arrival of M+ keystones last week and the Darkway delve. For raids, the Voidspire and the Dreamrift both opened on Mythic difficulty.  All other diff of the Dreamrift, the one-boss raid, opened the previous week.  For the Voidspire, LFR wing 2 is available, as is the as-yet-unimproved Story Mode version. Coming this week with the March 31 reset is wing 3 of LFR for VS along with the Normal, Heroic, and Mythic versions of the 3rd raid of Midnight, March on Quel'Danas. This is a 2-boss raid.  The Raid Finder/LFR and SM versions arrive the following week on April 7.  And the final delve, the Parhelion Plaza opens this week as well.  New nemesis for the season is Nullaeus, and Valeera Sanguinar is here to help you through all of the Delves. A Race to World First update? On Solo Queue? 9 bosses from all 3 of the raids, with of course the final 2 bosses taking the stage on Tuesday with the launch of the March on Quel'Danas. As of the time of recording, there are three familiar names that have cleared the first two raids and are awaiting the penultimate boss: Liquid, Echo, and Method.  Six more teams are trying to take down the final boss, identified as the Crown of the Cosmos in the Adventure Guide. Spring sale on Bnet – pets and mounts and packs of stuff, along with certain game services Twitch drop is the Cuddly Void Grrgle; before April 23; watch 4 hours of WoW on Twitch 0.5 preview of what is interesting No release date yet, but an 8 week cycle would be April 28, so there is still plenty of time. The Voidforge will help to upgrade gear. That said, the Nebulous Voidcores that you will need to upgrade gear come from M+ d, raids, Bountiful Delves, and Nightmare level Prey Hunts.  More open-world activities launch with 12.0.5 with Void Assaults comprised of Void Strkes and Void Incursions. Another activity is Ritual Sites, a tiered scenario that can be tackled solo or with a party of up to five players. Add the underwater fishing activity called Abyss Anglers and it seems like there will be a lot of options to freshen up your routine midway through Season 1 of Midnight.   Class Identity Challenge – 27:45 On Azeroth Morning Radio, Jibbs described his connection to the Paladin class to his own life and that got me thinking about why I identify with my favorite class, Druid of course.    Hero's Call Co-Opted – 36:33 And continuing with AMR-adjacent content, I low-key (as my 9th grade students say) stole the Hero's Call Board segment from them for a good reason, to highlight someone awesome in the WoW community.   “What Have You Done Lately?” – 53:56        Honestly, not enough Warcraft, but both Haranir characters have been created bringing the active roster to 69.  My oldest active character, and possibly my first character, is the first Horde character to start an expansion for me, and he has hit 90 and already wiped once in the “Story” Mode raid.  Oof.   Main Topic:  My Midnight Experience – 1:29:19 Walking through the leveling campaign going through my thoughts on the zones, storylines, music, graphics, and selected systems in Midnight. Silvermoon City – 1:39:22 Eversong Woods – 1:45:20 Arator's Journey – 1:55:22 Zul'Aman – 1:59:48 Harandar – 2:07:41 Voidstorm – 2:17:40   Closing Thoughts – 2:25:26 Wrapping it all up, including my brief thoughts on the so-called “Story” Mode raid for the Voidspire and a potential reveal of the final boss…   Outro – 2:37:10 Thanks to all of you for your patience in waiting for this episode, Blizzard for the amazing music and sound, to OGRE for intro/outro music, my lovely and supportive wife, my family, and YOU for listening. Support the show at https://www.patreon.com/soloqueuewow Thank you to contributing patrons Andrew, Righteous Bandy, ThatSkyGuy, Cyn, Snek of Voldun, Jon, Scott, Jeru, Raven, Greybeard, Case, Pasta Matt, Luch, and Rak!  And thanks to free members Max, Eddie, Bear, Friends of Wumpus, Sean, Curro, Aronaar, AedinNahkriin, Guardian Sandy, Alice, Don, Kamil, Wednesday, Eric, and TJ! Subscribe to the podcast at your podcast feed of choice, Apple, Spotify, and all the rest.  Leave a 5-star rating and a written review to help grow Solo Queue. You can contact me at soloqueuewow at gmail.com, Bluesky, Twitter, Facebook, Instagram, and Threads. Race to World First is…still a thing.  Go team. “I will see you out there."

This week, Sarah Bowen Shea is joined by Coach Liz Waterstraat for a conversation about one nonfiction title: The Way of Excellence by Brad Stulberg. The two talk about how excellence feels more like ease than strain, why values matter, and how curiosity, discipline, and reflection can help athletes, leaders, parents, and anyone else move toward growth.Liz also shares why this personal-development book stands out from the pack—and why it's worth the read.The Way of Excellence by Brad StulbergIQBAR - Get 20% off, plus free shipping, on all IQBAR products by texting AMR to 64000Momentous: Use code AMR for up to 35% off your first subscription order at https://www.livemomentous.com/Follow us on Instagram: https://www.instagram.com/themotherrunner/ Feisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/

In this episode of The New Warehouse Podcast, Kevin chats with Ben Hull, Director of Sales at Item America, about how modular warehouse solutions are reshaping operations. Item America, a German-based company with a growing U.S. presence, specializes in aluminum extrusion systems that allow teams to design and build custom solutions on the shop floor. From ergonomic workstations to AMR-compatible carts, the conversation explores how flexibility, customization, and continuous improvement are driving smarter warehouse design. Hull shares how modular thinking helps operations reduce waste, adapt faster, and create solutions that truly fit their needs.Learn more about sponsors here: EPG, iAutomate, Big Joe Forklifts, Surgere, Ocado Intelligent Automation Follow us on LinkedIn and YouTube.Support the show

Anyone looking to kickstart her running habit—or begin a new one—will appreciate this episode featuring Jennifer Harrison, a veteran endurance coach and accomplished triathlete, and sport psychologist Erin Haugen, Ph.D. Along with the hosting duo of Sarah Bowen Shea and Amanda Loudin, they discuss:how adding walks into your run can re-ignite joythe natural ebb and flow of exercisinggetting over the fear of re-injuryways to shed the dread of a runthat your “why” doesn't need to be a deep, meaningful thingBefore Coach Jen joins around 8:40, the hosts also enjoy a quick catch-up on work (Amanda) and family (Sarah).Momentous: Use code AMR for up to 35% off your first subscription order at https://www.livemomentous.com/IQBAR - Get 20% off, plus free shipping, on all IQBAR products by texting AMR to 64000Follow us on Instagram: https://www.instagram.com/themotherrunner/ Feisty Fest: Join us from September 18-20, 2026 - https://feisty.co/events/feisty-fest/

Your favorite book-recommendation podcast is back! Hosts Sarah Bowen Shea and Ellison Weist kick things off by talking about four novels from women writers, including a buzzy one Sarah enjoyed listening to on her runs.The Elopement: Gill HornbyKin: Tayari JonesGood People: Patmeena SabitMurder Bimbo: Rebecca NovackSupport our partners:Feisty + AMR appreciate your—and their—support!Get 20% off, plus free shipping, on all IQBAR products by texting AMR to 64-000Use code AMR for up to 35% off first subscription order at livemomentous.com

Are you great at burning fat—but struggling with recovery, muscle, energy, or stubborn body composition? In this Part 1 episode, Coach Debbie Potts takes you down a deep-dive rabbit hole into AMPK dominance, the "burn mode" many high performers and endurance athletes unknowingly live in. You'll learn how chronic stress, under-fueling, fasting, and excessive endurance training can shift your body into energy conservation instead of rebuilding—and why this becomes even more important in midlife. Debbie breaks down the difference between being a fat burner vs. metabolically flexible, and how PNOĒ metabolism testing reveals key clues at rest (RMR) and during exercise (AMR), including: • Low resting metabolic rate (RMR) and what it really means • Fat-burning dominance vs true metabolic flexibility • Poor high-intensity capacity and "flat" performance • Limited carbohydrate access when you need it most • Signs of chronic AMPK activation and reduced mTOR signaling This episode will help you understand why your body may feel stuck—even when you're doing everything "right"—and why the solution isn't more discipline, but better metabolic signaling and strategy. This is where you stop guessing… and start connecting the clues.

ON TODAYS PROGRAM…   MAX ON POLE TAKES VICTORY AT THE NURBURGRING AND IS DISQUALIFIED! HOURS LATER. THE WORLD KNOWS MERCEDES IS HOLDING BACK POWER! ASTON MARTIN'S WORKING ENVIRONMENT BECOMING UNCOMFORTABLE AS ADRIAN NEWEY IS REMOVED AS TEAM PRINCIPAL LEAVING ROOM FOR JONATHAN WHEATLEY TO TAKE OVER AND…THE MOST OBVIOUS QUESTION IS …WHEN WILL ANTONELLI REPLACE LEWIS AT FERRARI? THIS WEEK'S NASIR HAMEED CORNER WE HAVE: KAZUKI NAKAJIMA,  ASTON MARTIN ARAMCO FORMULA ONE™ TEAM STATEMENT FROM LAWRENCE STROLL. “With the current speculation surrounding Adrian Newey's role in our team, I want to take this opportunity to set the record straight. “As Executive Chairman and Controlling Shareholder, I would like to reaffirm that Adrian Newey is my partner and an important shareholder. He is AMR's Managing Technical Partner, and he and I have a true partnership built on a shared vision of success for the company. “We do things differently here, and while we don't currently adopt the traditional Team Principal role that you see elsewhere - it is by design. “As the most successful engineer ​in the history of the sport, Adrian's primary focus is on the strategic and technical leadership where he excels. He is supported by a highly skilled Senior Leadership Team to deliver on all aspects of the business, both at the Campus and trackside. “We are regularly approached by senior executives of other teams who wish to join Aston Martin Aramco, but in keeping with our policy, we do not comment on rumour and speculation.” New management structure for the Audi F1 Project. Jonathan Wheatley is leaving Audi Revolut F1 Team effective immediately for personal reasons Mattia Binotto assumes responsibilities as Team Principal in addition to his role as Head of Audi F1 Project   Audi CEO Gernot Döllner: “We will continue to pursue the path we have chosen with determination”   Audi has made an adjustment to the management structure of its Formula 1 project. In addition to his existing duties as Head of Audi F1 Project, Mattia Binotto will also assume the responsibilities of Team Principal. Jonathan Wheatley is leaving the Audi Revolut F1 Team with immediate effect for personal reasons. Wheatley had been part of the Audi F1 Project since April 2025. Together with Binotto, he built up the racing team at the Hinwil facility in Switzerland, which immediately scored points on its Formula 1 debut in early March. With this transition, Mattia Binotto will now assume additionally the responsibilities of Team Principal, taking leadership at the race track of Audi Revolut F1 Team. “We are grateful to Jonathan Wheatley for his contribution to the project during the crucial entry phase and wish him all the best for the future,” says Gernot Döllner, CEO of AUDI AG and Chairman of the Board of Management of Audi Motorsport AG. “Mattia Binotto and the team will continue to pursue the path we have chosen with determination. Our focus remains unchanged: we are concentrating all our efforts on building a team competing at the highest level that will challenge for world championships in Formula 1 by 2030. We will continuously develop our organizational structures to achieve our shared goal in a sustainable manner.”   Penske Entertainment Statement on Passing of Jim Michaelian   INDIANAPOLIS (Saturday, March 21, 2026) – A statement from Roger Penske about the passing March 21 of Grand Prix Association of Long Beach President and CEO Jim Michaelian: “Everyone at Penske Entertainment and within the INDYCAR community is deeply saddened by the passing of Jim Michaelian. Jim was a leader of a small, passionate group who believed in the concept of bringing elite open-wheel competition to Long Beach in the 1970s, worked tirelessly to make it happen despite steep odds and then helped nurture the Grand Prix of Long Beach into becoming America's premier street race. His vision and energy surrounding this great event remained boundless for 50 years, as no task was too small for Jim even while he served in numerous leadership roles. Penske Entertainment is committed to honoring Jim's legacy of putting fans and competitors first as we continue to build on the strong foundation he and his staff created for a half-century in Long Beach. Our deepest sympathies are with his wife, Mary, and their sons, Bob and Mike.”

Yes, we're BACK!Thanks to a merger with Feisty Media, this episode kicks off the return of Another Mother Runner (both the podcasts and the company!). In this live relaunch episode, hosts Sarah Bowen Shea and Britany Williams are joined by AMR co-founder Dimity McDowell and Sara Gross, founder and CEO of Feisty.Recorded in front of a lively audience at the Portland Running Company, the quartet discusses the myriad ways community matters, especially for active women—and they pull back the curtain on how these two women-centric, sporty brands joined forces.This show is a production of Another Mother Runner and Feisty Media. Learn more about Feisty—their community, other shows, workshops, and events, including FeistyFest.Episode resources:Feisty: feisty.coFeistyFest: feisty.co/events/feisty-fest/

Send a textImagine this scene:A family's house was destroyed when it was bombed during a war. They got out with the clothes on their backs – nothing more. When they were fleeing, the mother was hit with fragments from another bomb. It tore off part of her leg. Dirt got in the wound.They made it to a refugee camp, but the wound got infected. With nothing available to treat the injury, the infection got worse. She had a drug-resistant infection that wasn't treatable with regular antibiotics. Her entire leg and part of her hip had to be removed to save her life. She will have a physical disability for the rest of her life.This is just one story of drug resistance or antimicrobial resistance (AMR)  and the impact of armed conflict. Report after report finds that victims of armed conflict and refugees – both those seeking shelter abroad and inside their own countries – are especially likely to suffer from drug-resistant infections.Dr. Aula Abbara, Consultant in Infectious Diseases and Acute Medicine and Honorary Senior Clinical Lecturer at Imperial College, London, has been studying the problem firsthand.She's worked with teams that found people injured in Syria's 15-year-long conflict not only suffered terrible wounds, but then developed worse infections because of crowded and unsanitary conditions in healthcare facilities. These war-damaged hospital laboratories in Syria, especially, lacked the capacity to test for drug-resistant bacteria, and so doctors didn't know which antibiotics to prescribe to treat patients' infections.Solutions require taking a One Health approach, Dr. Abbara and colleagues have found.She and her colleagues call for programs to bring in more health professionals and healthcare access; introduction of easy-to-use diagnostics so people's infections can be immediately diagnosed and thus treated with the correct drugs; stopping the improper use and distribution of antibiotics; and proper surveillance so that professionals know which drug-resistant infections are spreading and where.In this episode of One World, One Health, Dr. Abbara chats with host Maggie Fox about what she's seen and what might help.

WHAT YOU'LL LEARN Why retail is now a demand chain, not a supply chain How AMRs deliver 6–12 month ROI in high-variability e-commerce Why robotics-as-a-service changes peak capacity planning The real bottleneck in AI adoption: structured WMS data Why dashboards are dying and exception-based orchestration is rising How consolidation will reshape 3PL economics Why operational excellence remains the ultimate differentiator HIGHLIGHTS 00:01–00:12 | Consumer expectations and the “fast + free + cheap” reality 00:12–00:15 | AMRs, ASRS, RaaS, and 6–12 month automation ROI 00:15–00:16 | Buy vs build: what's commodity vs “secret sauce” 00:16–00:19 | Agentic AI in warehouse ops: labor planning + execution 00:19–00:22 | AI proof, case studies, and demand planning as the next frontier 00:22–00:24 | Dashboards vs operators: turning analytics into actions 00:24–00:28 | Operator advice: efficiency, mechanization, and competition shifts 00:29–00:31 | Manifest trends: retail channels evolving + tech-driven 3PL future QUOTES  [00:04:10] “One of the biggest changes is you used to have a choice. You could either have it fast, you could have it free, or you could have it cheap. The consumer today wants all three.” – Jeff Wolpov [00:05:10] “We as logistics supply chain companies need to lean in and figure out how to do more with less. Today it's a necessity.” – Jeff Wolpov [00:07:30] “You need automation... We need to be faster and more flexible. Peaks have gotten much higher.” – Jeff Wolpov [00:16:00] "The hard part isn't building AI or using AI. It's what do you do with the results?" - Gary Allen [00:16:50] “Operators shouldn't hunt dashboards, they should get alerts, exception-based triggers. AI takes analytics to the next level.” – Gary Allen [00:23:00] "Reporting is the death of analytics." - Gary Allen  ABOUT THE GUESTS Jeff Wolpov Jeff Wolpov is Senior Vice President of E-commerce and Ryder Last Mile at Ryder System, Inc., where he leads the vision and strategy for omnichannel fulfillment and big & bulky home delivery. Previously, he served as CEO of Whiplash (formerly Port Logistics Group), achieving nearly 30% year-over-year revenue growth before its acquisition by Ryder in 2022. Earlier in his career, Jeff founded Distribution Solutions, scaling it from a startup into a $50 million regional logistics firm that became the foundation of Whiplash's national network. He holds a degree from the University of Michigan. Gary Allen Gary Allen is Vice President of Supply Chain Excellence at Ryder, overseeing Solution Design, Continuous Improvement, Data Analytics, and Automation across the supply chain organization. With more than 32 years of experience, he previously led EY's logistics consulting practice and held leadership roles at DHL and FedEx in product innovation, solution design, sustainability, and operations. Gary helped launch and co-author the “Annual Third Party Logistics Study” with Dr. John Langley of Penn State University and holds a Bachelor of Arts in Materials and Logistics Management from Michigan State University. LINKS MENTIONED Ryder report: https://www.ryder.com/en-us/insights/white-papers/e-comm/2025-ryder-e-commerce-consumer-study Ryder website: https://www.ryder.com/en-us Subscribe and Keep Learning!If you're a logistics leader looking to scale sustainably, don't miss out! Subscribe for more expert strategies on tackling modern supply chain challenges.Be sure to follow and tag the eCom Logistics Podcast on LinkedIn and YouTube

Antimicrobial resistance, or AMR, is often described as a silent pandemic. With antibiotics losing their effectiveness due to overuse and misuse, we look at how serious India's AMR burden is and why drug-resistant infections are rising. The Indian Express' Rinku Ghosh and Shashank Bhargava speak with Dr Kamini Walia of the Indian Council of Medical Research about what is driving this crisis and what can be done to slow it.Hosted by Ichha SharmaProduced and written by Shashank Bhargava and Ichha SharmaEdited and mixed by Suresh Pawar

CardioNerds (Dr. Shazli Khan, Dr. Jenna Skowronski, and Dr. Shiva Patlolla) discuss the management of patients post‑heart transplantation with Dr. Shelley Hall from Baylor University Medical Center and Dr. MaryJane Farr from UTSW. In this comprehensive review, we cover the physiology of the transplanted heart, immunosuppression strategies, rejection surveillance, and long-term complications including cardiac allograft vasculopathy (CAV) and malignancy. Audio editing for this episode was performed by CardioNerds intern Dr. Bhavya Shah. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Heart Success Series PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls The Denervated Heart: The donor heart is surgically severed from the autonomic nervous system, leading to a higher resting heart rate (90-110 bpm) due to loss of vagal tone. Because the heart relies on circulating catecholamines rather than neural input to increase heart rate, patients experience a delayed chronotropic response to exercise and stress. Importantly, because afferent pain fibers are severed, ischemia is often painless. Rejection Surveillance: Rejection is classified into Acute Cellular Rejection (ACR), which is T-cell mediated, and Antibody-Mediated Rejection (AMR), which is B-cell mediated. While endomyocardial biopsy remains the gold standard for diagnosis, non-invasive surveillance using gene-expression profiling (e.g., AlloMap) and donor-derived cell-free DNA (dd-cfDNA) is increasingly utilized to reduce the burden of invasive procedures. The Infection Timeline: The risk of infection follows a predictable timeline based on the intensity of immunosuppression. The first month is dominated by nosocomial infections. Months one through six are the peak for opportunistic infections (Cytomegalovirus, Pneumocystis, Toxoplasmosis) requiring prophylaxis. After six months, patients are primarily at risk for community-acquired pathogens, though late viral reactivation can occur. Cardiac Allograft Vasculopathy (CAV): Unlike native coronary artery disease, CAV presents as diffuse, concentric intimal thickening that affects the entire length of the vessel, including the microvasculature. Due to denervation, patients rarely present with angina; instead, CAV manifests as unexplained heart failure, fatigue, or sudden cardiac death. Malignancy Risk: Long-term immunosuppression significantly increases the risk of malignancy. Skin cancers (squamous and basal cell) are the most common, followed by Post-Transplant Lymphoproliferative Disorder (PTLD), which is often driven by Epstein-Barr Virus (EBV) reactivation. Notes Notes: Notes drafted by Dr. Patlolla 1. What are the unique physiological features of the transplanted heart? The hallmark of the transplanted heart is denervation. Because the autonomic nerve fibers are severed during harvest, the heart loses parasympathetic or vagal tone, resulting in a resting tachycardia (typically 90-110 bpm). The heart also loses the ability to mount a reflex tachycardia; thus, the heart rate response to exercise or hypovolemia relies on circulating catecholamines, which results in a slower “warm-up” and “cool-down” period during exertion. 2. What are the pillars of maintenance immunosuppression regimen? The triple drug maintenance regimen typically consists of: Calcineurin Inhibitor (CNI): Tacrolimus is preferred over cyclosporine. Key side effects include nephrotoxicity, hypertension, tremor, hyperkalemia, and hypomagnesemia. Antimetabolite: Mycophenolate mofetil (MMF) inhibits lymphocyte proliferation. Key side effects include leukopenia and GI distress. Corticosteroids: Prednisone is used for maintenance but is often weaned to low doses or discontinued after the first year to mitigate metabolic side effects (diabetes, osteoporosis, weight gain). 3. How is rejection classified and diagnosed? Rejection is the immune system’s response to the foreign graft and is categorized by the arm of the immune system involved: Acute Cellular Rejection (ACR): Mediated by T-lymphocytes infiltrating the myocardium. It is graded from 1R (mild) to 3R (severe) based on the extent of infiltration and myocyte damage. Antibody-Mediated Rejection (AMR): Mediated by B-cells producing donor-specific antibodies (DSAs) that attack the graft endothelium. It is diagnosed via histology (capillary swelling) and immunofluorescence (C4d staining). Diagnosis has historically relied on endomyocardial biopsy. However, non-invasive tools are gaining traction. Gene Expression Profiling (GEP) assesses the expression of genes associated with immune activation to rule out rejection in low-risk patients. Donor-Derived Cell-Free DNA (dd-cfDNA) measures the fraction of donor DNA in the recipient’s blood. Elevated levels suggest graft injury which can occur in both ACR and AMR. 4. What is the timeline of infectious risk and how does it guide prophylaxis? Infectious risk correlates with the net state of immunosuppression. < 1 Month (Nosocomial): Risks include surgical site infections, catheter-associated infections, and aspiration pneumonia. 1 – 6 Months (Opportunistic): This is the period of peak immunosuppression. Patients are at risk for PJP, CMV, Toxoplasma, and fungal infections. Prophylaxis typically includes Trimethoprim-Sulfamethoxazole (for PJP/Toxo) and Valganciclovir (for CMV, dependent on donor/recipient serostatus). > 6 Months (Community-Acquired): As immunosuppression is weaned, the risk profile shifts toward community-acquired respiratory viruses (Influenza, RSV) and pneumonias. However, patients with recurrent rejection requiring boosted immunosuppression remain at risk for opportunistic pathogens. 5. How does Cardiac Allograft Vasculopathy (CAV) differ from native CAD? CAV is the leading cause of late graft failure. Unlike the focal, eccentric plaques seen in native atherosclerosis, CAV is an immunologically driven process causing diffuse, concentric intimal hyperplasia. It affects both epicardial vessels and the microvasculature. Because of this diffuse nature, percutaneous coronary intervention (PCI) is often technically difficult and provides only temporary palliation. The only definitive treatment for severe CAV is re-transplantation. Surveillance is critical and is typically performed via annual coronary angiography, often using intravascular ultrasound (IVUS) to detect early intimal thickening before it is visible on the angiogram. References Costanzo MR, Dipchand A, Starling R, et al. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Heart Lung Transplant. 2010;29(8):914-956. doi:10.1016/j.healun.2010.05.034. https://www.jhltonline.org/article/S1053-2498(10)00358-X/fulltext Kittleson MM, Kobashigawa JA. Cardiac Allograft Vasculopathy: Current Understanding and Treatment. JACC Heart Fail. 2017;5(12):857-868. doi:10.1016/j.jchf.2017.07.003. https://www.jacc.org/doi/10.1016/j.jchf.2017.07.003 Velleca A, Shullo MA, Dhital K, et al. The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Heart Lung Transplant. 2023;42(5):e1-e141. doi:10.1016/j.healun.2022.10.015. https://www.jhltonline.org/article/S1053-2498(22)02187-5/fulltext

Three co-hosts sit down and share in this second installment of this annual tradition-episode: Molly Williams, Tish Hamilton, and the OG herself, Dimity McDowell. Along with host Sarah Bowen Shea, each gal shares her 2025 physical pursuits—as well as their plans for 2026. There is also the detailed background of the AMR origin story, plus laughter and tears remembering past episodes (hello, Chris McDougall and his “ass!”) and in-person AMR adventures.    Head here to sign up for notifications about the potential continuation of AMR podcasts.     When you shop our sponsors, you help AMR.We appreciate your—and their—support!   Save 15% thru 1/31/26w/ code AMRwinter25 at topoathletic.com   Use code AMR for up to 35% off first subscription order at livemomentous.com   Get 20% off, plus free shipping, on all IQBAR products by texting AMR to 64-000 Learn more about your ad choices. Visit megaphone.fm/adchoices