POPULARITY
Join DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard as she reviews the recent article published in Antimicrobial Stewardship & Healthcare Epidemiology titled: “(Re)Moving the Needle: A Retrospective, Quasi-Experimental Assessment of the Impact of a Treatment Guideline on Oral Antibiotic Prescribing for Orthopedic Infections." She discusses how this study highlights the real-world impact of guideline implementation on shifting antibiotic prescribing practices for bone and joint infections. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/40160226/ For more information about DASON, please visit: https://dason.medicine.duke.edu/
A common yet often misunderstood infection is popping up in different corners of our community. Mycoplasma pneumonia, otherwise referred to as walking pneumonia, can present in a way that's subtle and sneaky, with a plethora of symptoms. This ‘silent' infection can fly under the radar leaving both patients and providers puzzled, but we want to make sure our listeners feel prepared to tackle this diagnosis. How do we ensure it doesn't slip through the cracks? How do we identify it in our patients? We'll discuss all that and more in this episode. Joining us for this exciting discussion are Lilliam Ambroggio, PhD, and Michael Bozzella, DO. Dr. Ambroggio is the Director of Research in the sections of Emergency Medicine and Hospital Medicine at Children's Hospital Colorado. She is also an Associate Professor of Pediatrics at the University of Colorado School of Medicine. Dr. Bozzella is the Associate Medical Director of Antimicrobial Stewardship and specializes in infectious disease. He is also an Assistant Professor of Pediatrics. Some highlights from this episode include: Understanding where it colonizes and how it spreads How to identify this disease properly, as the presentation can look like many different illnesses How the epidemiology informs what primary care providers should know about this diagnosis Knowing when to test For more information on Children's Colorado, visit: childrenscolorado.org.
Send us a textDr. Jennifer Granick takes us deep into her groundbreaking research on antibiotic prescribing patterns in companion animal practice, revealing both challenges and opportunities for improvement.This conversation unveils the complex reality of veterinary prescribing. Perhaps most surprising is the finding that preventive antibiotic treatments typically last the same duration (10 days) as those targeting confirmed infections—a practice without scientific justification.What makes this discussion particularly valuable is Dr. Granick's practical approach to creating change. Rather than overwhelming practitioners with an insurmountable challenge, she advocates starting small: "Pick one common condition, check prescribing guidelines, and make one small change." This accessible strategy empowers veterinarians to contribute meaningfully to antimicrobial stewardship without complete practice overhauls. Meanwhile, pet owners gain crucial perspective on when antibiotics truly help versus when they might cause harm.As Dr. Granick's team explores innovative methods using electronic health records and AI to gather prescribing data while maintaining privacy, the future of veterinary antimicrobial stewardship looks promising. Her parting wisdom serves as both warning and hope: antibiotics are indeed life-saving, but only if they continue to work. Join us for this essential conversation at the intersection of companion animal medicine, public health, and our shared responsibility to preserve these precious medications for generations to come.Open access JAVMA article: https://doi.org/10.2460/javma.24.11.0716INTERESTED IN SUBMITTING YOUR MANUSCRIPT TO JAVMA ® OR AJVR ® ? JAVMA ® : https://avma.org/JAVMAAuthors AJVR ® : https://avma.org/AJVRAuthorsFOLLOW US:JAVMA ® : Facebook: Journal of the American Veterinary Medical Association - JAVMA | Facebook Instagram: JAVMA (@avma_javma) • Instagram photos and videos Twitter: JAVMA (@AVMAJAVMA) / Twitter AJVR ® : Facebook: American Journal of Veterinary Research - AJVR | Facebook Instagram: AJVR (@ajvroa) • Instagram photos and videos Twitter: AJVR (@AJVROA) / Twitter JAVMA ® and AJVR ® LinkedIn: https://linkedin.com/company/avma-journals
In this episode, listen in as our expert panel digs into identifying and treating acute bronchitis and community-acquired pneumonia. They'll discuss when antibiotics are appropriate, which antibiotics to use, and other management tips.You'll also hear practical advice from panelists on TRC's Editorial Advisory Board:Stephen Carek, MD, CAQSM, DipABLM, Program Director for the Prisma Health/USC School of Medicine Greenville Family Medicine Residency Program and Clinical Associate Professor at the University of South Carolina School of Medicine, GreenvilleAndrea Darby Stewart, MD, Associate Director, Honor Health Family Medicine Residency Program and Clinical Professor of Family, Community & Occupational Medicine at the University of Arizona College of Medicine - PhoenixCraig D. Williams, PharmD, FNLA, BCPS, Clinical Professor of Pharmacy Practice at the Oregon Health and Science UniversityNone of the speakers have anything to disclose.This podcast is an excerpt from one of TRC's monthly live CE webinars, the full webinar originally aired in January 2025.TRC Healthcare offers CE credit for this podcast. Log in to your Pharmacist's Letter, Pharmacy Technician's Letter, or Prescriber Insights account and look for the title of this podcast in the list of available CE courses.Claim CreditThe clinical resources mentioned during the podcast are part of a subscription to Pharmacist's Letter, Pharmacy Technician's Letter, and Prescriber Insights: Chart: Managing Community-Acquired Pneumonia and Aspiration Pneumonia in AdultsFAQ: Antibiotic Therapy: When Are Shorter Courses Better?Chart: Managing Cough and Cold SymptomsSend us a textCheck out our NEW podcasts. Rumor vs TruthYour trusted source for facts... where we dissect the evidence behind risky rumors and reveal clinical truths.Clinical CapsulesTRC editors break down the most impactful clinical developments - giving you clear, actionable takeaways in just minutes.If you're not yet a subscriber, find out more about our product offerings at trchealthcare.com. Follow, rate, and review this show in your favorite podcast app. Find the show on YouTube by searching for ‘TRC Healthcare' or clicking here. You can also reach out to provide feedback or make suggestions by emailing us at ContactUs@trchealthcare.com.
You can text us here with any comments, questions, or thoughts!In our latest episode, Kemi sit down with Dr. Sharon Onguti, an infectious diseases specialist at Vanderbilt University Medical Center, where she has served since 2022. Board-certified in Internal Medicine and Infectious Diseases, she completed her fellowship at UT Health San Antonio and a sub-fellowship in Antimicrobial Stewardship at Stanford University. Dr. Onguti holds an MPH in Epidemiology and Biostatistics from Johns Hopkins Bloomberg School of Public Health and is a board member of the Society of Bedside Medicine, she is dedicated to medical education and serves as Associate Program Director of the Infectious Diseases Fellowship Program. She is also is an alumnus of our Get That Grant® coaching program! Join the conversation as Dr. Onguti shares her remarkable journey in medicine, highlighting her innovative use of AI in healthcare. Highlights: Discover how she navigates multiple roles and responsibilities while finding clarity and focus through coaching. The importance of aligning your career with personal values and interests. Why regular reflection and inventory of your activities help ensure alignment with long-term goals. Insights on cultivating a high-functioning support network and redefining mentorship to propel your career forward. Loved this convo? Please go find Dr. Onguti on LinkedIn and Twitter/X show her some love! If you'd like to learn more foundational career navigation concepts for women of color in academic medicine and public health, sign up for our KD Coaching Foundations Series: www.kemidoll.com/foundations. And if you're also a high-achieving WOC facing these challenges and seeking to navigate your path more effectively, Get That Grant is here to support you! Join the waitlist for our April 2025 Get That Grant cohort! Enrollment for the April cohort is exclusive to our waitlist, so sign up now to take the first step toward turning your aspirations into reality. Applications will be sent directly to the waitlist on Monday, February 17. Sign up for the waitlist now at www.kemidoll.com/gtgwaitlist REMINDER: Your Unapologetic Career Podcast now releases episode every other week! Can't wait that long? Be sure you are signed up for our newsletter (above) where there are NEW issues every month!
In this episode of the SHEA Podcast, moderator Dr. Sheetal Kandiah, Director of the Antimicrobial Stewardship Program at Emory University Hospital, explores the role of Artificial Intelligence (AI) in antimicrobial stewardship with Dr. Richard Medford, ECU Health's Chief Medical Informatics and Digital Health Officer (CMIDHO). Dr. Medford discusses how AI-driven tools are transforming antibiotic stewardship, improving prescribing accuracy, patient outcomes, and resistance management. The conversation highlights current applications, including predictive analytics and clinical decision support, as well as the impact of big data on stewardship programs. The episode also examines real-world successes where AI has optimized antibiotic use and enhanced patient care, along with key challenges in AI adoption, such as data reliability, ethical concerns, and provider trust. Looking ahead, Dr. Medford shares insights on future AI advancements that could further shape antimicrobial stewardship and healthcare innovation.
In this episode, Mike and Julian are joined by Fergus Allerton, a leading voice in antimicrobial stewardship within veterinary medicine, to tackle the pressing issue of antimicrobial resistance (AMR).They kick things off with a light-hearted chat about sore throats and antibiotics before diving into the complexities of AMR and the global risks it poses. Fergus breaks down how antimicrobial resistance develops, why responsible antibiotic use is critical, and highlights key initiatives like the PROTECT ME guidelines and Antibiotic Amnesty.The conversation also explores parallels between human and veterinary medicine, the role of education—especially for children, and how One Health links human and animal health.Fergus shares his personal experiences, including his work as an independent visitor with Barnardo's and his passion for veterinary medicine. To wrap up, he takes on the 60-second CPD challenge, offering practical, actionable steps for vets to make a real impact in antimicrobial stewardship.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode999. In this episode, I'll discuss whether delayed broad-spectrum antibiotics have an impact on clinical outcomes. The post 999: Is This Study a Breakthrough for Antimicrobial Stewardship? appeared first on Pharmacy Joe.
On this episode of The ICHE Podcast, we dive into research priorities in healthcare-associated infections (HAIs) and antimicrobial stewardship (AS) with experts Robin Jump, Jennie Kwon, Daniel Livorsi, Lona Mody, and Eli Perencevich. The discussion explores the importance of publishing research agendas to stimulate focused research, guide researchers in prioritizing critical topics, and inform funding decisions. By addressing these goals, the panel aims to align research efforts with pressing clinical challenges, foster innovation, and bridge gaps between research and implementation. The guests also discuss the structured methodologies used to draft these research agendas, detailing how key priorities were identified and refined to address the most urgent needs in the field. The panel reviews three recently published agendas in ICHE: A Call to Action: The SHEA Research Agenda to Combat Healthcare-Associated Infections, Research Agenda for Transmission Prevention within the Veterans Health Administration, 2024–2028, and Research Agenda for Antibiotic Stewardship within the Veterans Health Administration, 2024–2028. Key topics include addressing antimicrobial resistance, improving diagnostic tools, and tackling HAIs in vulnerable populations. The conversation further examines the applicability of findings from VA-specific agendas to non-VA healthcare settings, concluding that many insights are broadly relevant. Listeners will gain a clearer understanding of the research landscape and actionable ways to contribute to advancements in patient safety and healthcare quality. For further details, explore the full articles discussed in this episode at Cambridge.org/ICHE.
In this episode of The SHEA Podcast, host Dr. Leila Hojat is joined by Dr. Pretti Jaggi and Dr. Emily Spivak to explore the growing intersection of antimicrobial stewardship and sustainability in healthcare. The discussion highlights how stewardship programs can reduce the environmental impact of antibiotic production and use, particularly by addressing pharmaceutical waste. The guests share insights into how optimizing antibiotic use promotes more efficient resource utilization, contributing to a broader sustainability agenda. They emphasize the alignment of combating antibiotic resistance with the goals of sustainable healthcare, underscoring the long-term benefits of this synergy. Interdisciplinary approaches, blending antimicrobial stewardship with environmental science and public health, are highlighted as promising solutions to infectious disease management. The conversation also delves into future innovations in stewardship practices, including advancements in technology and collaboration, which are expected to drive significant progress in sustainable healthcare.
In this episode Dhineli Perera speaks to John Turnidge, who leads the national surveillance program for Antimicrobial Use and Resistance in Australia. They discuss the significant impact of the pandemic on reducing antibiotic use in the community, and how this benefit can be sustained and improved on. Read the full article by John and his co-authors, Carolyn Hullick and Kim Stewart, in Australian Prescriber.
In this special episode for World Antimicrobial Resistance Awareness Week, we welcome Dr. Grace Barnes, a specialty registrar in Infectious Diseases and Microbiology, for an insightful discussion about her journey in medicine and her work in microbiology. Grace shares her path from studying medicine at Oxford University to her current role, including her formative experiences during medical electives in Australia and Hong Kong that sparked her interest in global health. She offers a fascinating glimpse into her daily work as a microbiologist, explaining how she bridges the gap between laboratory science and clinical care while collaborating with biomedical scientists, pharmacists, and other healthcare professionals to manage complex infections. The conversation explores the crucial role of multidisciplinary teamwork in treating antibiotic-resistant infections, with Grace highlighting specific examples of how collaboration between microbiologists and pharmacists leads to better patient outcomes. This episode provides valuable insights into the specialised world of clinical microbiology and infectious diseases, while highlighting the critical importance of collaborative healthcare in addressing modern medical challenges. HAVE YOU EVER THOUGHT ABOUT LIFE OUTSIDE THE TRADITIONAL 9-5? Are you a pharmacist dreaming of: - Working on your own terms? - Achieving location independence? - Building financial freedom? I've been there. That's why I'm sharing my journey from traditional 9-5 pharmacist to creating a life of freedom and fulfillment. In this weekly newsletter, I'll be opening up about my transition to unconventional pharmacy, practical tips for working on your own terms, strategies for financial independence, and our family's adventures in homeschooling and world travel. Ready to reimagine what's possible in your pharmacy career and life? Sign up
In this World Antimicrobial Resistance Awareness Week episode, we meet Bee Yean Ng, the lead antimicrobial stewardship pharmacist at Oxford University Hospitals NHS Trust. Starting her journey in Malaysia and completing her pharmacy degree through a partnership with the University of Strathclyde, Bee shares her transition from community pharmacy training to hospital practice. Despite initial challenges in making this sector switch, her positive mindset and flexibility to relocate helped her seize new opportunities. During her foundational years at Buckinghamshire Healthcare NHS Trust, Bee worked under the mentorship of Claire Brandish and Kate Russell-Hobbs, who helped shape her clinical development. Bee's career took an international turn when she became involved with the Commonwealth Partnership for Antimicrobial Stewardship grant, working between the UK and Uganda. This experience, combined with the Chief Pharmaceutical Officer's Global Health Fellowship, sparked her passion for global health and led to her first publication. Now at Oxford, she leads a partnership with Kilifi County Referral Hospital in Kenya, demonstrating her growth from team member to project leader. HAVE YOU EVER THOUGHT ABOUT LIFE OUTSIDE THE TRADITIONAL 9-5? Are you a pharmacist dreaming of: - Working on your own terms? - Achieving location independence? - Building financial freedom? I've been there. That's why I'm sharing my journey from traditional 9-5 pharmacist to creating a life of freedom and fulfillment. In this weekly newsletter, I'll be opening up about my transition to unconventional pharmacy, practical tips for working on your own terms, strategies for financial independence, and our family's adventures in homeschooling and world travel. Ready to reimagine what's possible in your pharmacy career and life? Sign up
In this World Antimicrobial Resistance Awareness Week episode, Neha Voralia shares her journey from community pharmacy to becoming an advanced anti-infectives pharmacist. Starting at Northampton General Hospital, she discovered her passion for antimicrobial stewardship through working with complex diabetic foot infections and surgical patients. Neha discusses her transition to paediatric antimicrobial stewardship at Great Ormond Street Hospital, highlighting the unique challenges of managing resistant infections in children, from dosing complexities to medication adherence. Now working at Buckinghamshire NHS Trust, she reflects on the evolving nature of antimicrobial pharmacy and her aspirations in infectious diseases. KEY TAKEAWAYS: Antimicrobial stewardship requires extensive knowledge of bacteria, resistance patterns, and complex patient factors. Paediatric antimicrobial management presents unique challenges, from dose calculations to medication adherence strategies. The role extends beyond clinical work to include guideline development, infection prevention, and regional collaboration. Tertiary centers manage particularly complex cases where standard guidelines may not apply. Professional development opportunities in antimicrobial stewardship include research, conference presentations, and global health initiatives. HAVE YOU EVER THOUGHT ABOUT LIFE OUTSIDE THE TRADITIONAL 9-5? Are you a pharmacist dreaming of: - Working on your own terms? - Achieving location independence? - Building financial freedom? I've been there. That's why I'm sharing my journey from traditional 9-5 pharmacist to creating a life of freedom and fulfillment. In this weekly newsletter, I'll be opening up about my transition to unconventional pharmacy, practical tips for working on your own terms, strategies for financial independence, and our family's adventures in homeschooling and world travel. Ready to reimagine what's possible in your pharmacy career and life? Sign up
In this special episode of Pharmacist Diaries, recorded live during World Antimicrobial Resistance Awareness Week, I welcome back Claire Brandish, a distinguished leader in antimicrobial stewardship and global health. Claire Brandish currently works as the Lead Anti-Infectives pharmacist at Buckinghamshire Healthcare NHS Trust and Senior Antimicrobial Resistance Technical Advisor for the Commonwealth Pharmacist Association. In her role, she supports the Fleming funded Commonwealth Partnerships for Antimicrobial Stewardship Scheme (CwPAMS). As a Chief Pharmaceutical Officer's Global Health Fellow, Claire has successfully delivered three CwPAMS projects between the NHS and health-partners in the UK and Uganda. Named a "Woman to Watch" in 2021 by the Pharmaceutical Journal, Claire works as an independent prescriber and actively participates in regular antimicrobial stewardship ward rounds as part of the multidisciplinary team. Key Takeaways - Global health partnerships offer valuable opportunities for professional growth and knowledge exchange - Success in healthcare leadership requires continuous learning, mentorship, and willingness to step outside comfort zones - Effective antimicrobial stewardship requires collaboration across multiple healthcare sectors and disciplines - Personal development and career progression often involve overcoming challenges and maintaining resilience HAVE YOU EVER THOUGHT ABOUT LIFE OUTSIDE THE TRADITIONAL 9-5? Are you a pharmacist dreaming of: - Working on your own terms? - Achieving location independence? - Building financial freedom? I've been there. That's why I'm sharing my journey from traditional 9-5 pharmacist to creating a life of freedom and fulfillment. In this weekly newsletter, I'll be opening up about my transition to unconventional pharmacy, practical tips for working on your own terms, strategies for financial independence, and our family's adventures in homeschooling and world travel. Ready to reimagine what's possible in your pharmacy career and life? Sign up
In this World Antimicrobial Resistance Awareness Week (WAAW) episode, Rachel Berry shares her journey from hospital pharmacist to antimicrobial stewardship specialist. Her passion deepened when her young son was diagnosed with leukemia, highlighting the critical importance of effective antibiotics in modern medicine. Now working at the UK Health Security Agency (UKHSA) as a Chief Pharmaceutical Officer's Fellow, Rachel combines her clinical expertise with national policy work. The conversation covers the evolution of pharmacy practice, the value of independent prescribing qualifications, and the urgent need to preserve antimicrobial effectiveness for future generations. 5 key takeaway messages: Antimicrobial resistance is an immediate threat affecting patient outcomes today, not a future concern. Pharmacy careers can evolve from ward-based roles to national policy influence through continuous development. Working with chronic conditions provides invaluable experience in managing complex infections and building patient relationships. National leadership programs like the Chief Pharmaceutical Officer's Fellowship enable pharmacists to shape healthcare policy. Career advancement can be strategically timed with different life stages without compromising family commitments. HAVE YOU EVER THOUGHT ABOUT LIFE OUTSIDE THE TRADITIONAL 9-5? Are you a pharmacist dreaming of: - Working on your own terms? - Achieving location independence? - Building financial freedom? I've been there. That's why I'm sharing my journey from traditional 9-5 pharmacist to creating a life of freedom and fulfillment. In this weekly newsletter, I'll be opening up about my transition to unconventional pharmacy, practical tips for working on your own terms, strategies for financial independence, and our family's adventures in homeschooling and world travel. Ready to reimagine what's possible in your pharmacy career and life? Sign up
In this powerful World Antimicrobial Resistance Awareness Week (WAAW) special episode, we hear from Vanessa Carter, a remarkable Antimicrobial Resistance (AMR) survivor turned global health advocate. After a devastating car accident in 2004 led to multiple facial reconstruction surgeries, Vanessa developed a drug-resistant MRSA infection that changed her life's trajectory. Her journey from patient to Chair of the WHO Task Force of AMR Survivors highlights the critical importance of patient education and antimicrobial stewardship. Vanessa shares crucial insights about the gaps in patient communication, the need for better infection prevention education, and the importance of tracking antibiotic usage. Key Takeaway Messages: For Healthcare Professionals: Simple, clear communication about infection risks can save lives Consider patient literacy levels when explaining complex concepts Integrate infection prevention education throughout the patient journey Collaborate across specialties for better patient outcomes For Patients: Ask questions about infection prevention and control Keep records of antibiotic treatments when possible Watch for signs of recurring infections Don't hesitate to seek help if infections don't improve For Policy Makers: Include patient voices in healthcare system design Invest in better diagnostic tools Develop integrated antibiotic tracking systems Support early education initiatives about AMR HAVE YOU EVER THOUGHT ABOUT LIFE OUTSIDE THE TRADITIONAL 9-5? Are you a pharmacist dreaming of: - Working on your own terms? - Achieving location independence? - Building financial freedom? I've been there. That's why I'm sharing my journey from traditional 9-5 pharmacist to creating a life of freedom and fulfillment. In this weekly newsletter, I'll be opening up about my transition to unconventional pharmacy, practical tips for working on your own terms, strategies for financial independence, and our family's adventures in homeschooling and world travel. Ready to reimagine what's possible in your pharmacy career and life? Sign up
Frances Garraghan, Consultant Pharmacist at Manchester University NHS Foundation Trust and AMR Technical Lead for the Commonwealth Pharmacist Association, shares her inspiring journey from NHS pharmacist to global Antimicrobial Resistance (AMR) leader. In this wonderful conversation, Fran reveals how she transitioned from surgery to antimicrobial stewardship, driven by personal experiences that shaped her career path. She discusses the unique challenges of tackling high resistance rates in Manchester's diverse patient population and how this led to innovative training programs incorporating behavioural science principles. The episode delves deep into Fran's transformative work with the Commonwealth Pharmacists Association (CPA), particularly her experiences in Uganda where she helped train over 200 healthcare workers. She shares candid insights about culture shock, adaptation, and the profound impact of global health work on her NHS practice. You will gain valuable insights into the development of sustainable healthcare partnerships, the importance of behavioural change in antimicrobial stewardship, and the critical role of pharmacists in global health initiatives. Fran's story illuminates how local NHS experience can translate into meaningful global impact, while emphasising the importance of cultural competency and adaptability in healthcare leadership. HAVE YOU EVER THOUGHT ABOUT LIFE OUTSIDE THE TRADITIONAL 9-5? Are you a pharmacist dreaming of: - Working on your own terms? - Achieving location independence? - Building financial freedom? I've been there. That's why I'm sharing my journey from traditional 9-5 pharmacist to creating a life of freedom and fulfillment. In this weekly newsletter, I'll be opening up about my transition to unconventional pharmacy, practical tips for working on your own terms, strategies for financial independence, and our family's adventures in homeschooling and world travel. Ready to reimagine what's possible in your pharmacy career and life? Sign up
Topics covered: - Defining antimicrobial stewardship- New randomized clinical trial looking at how stewardship prompts improve antibiotic selection for pneumonia- Resources and how CommonSpirit Health is taking action and addressing this important topicGuest expert: Dr. Renuga Vivekanandan, Infectious Disease Expert, Division VP and CMO Physician Enterprise - Midwest, Professor, Associate Dean for Clinical Affairs, Creighton University School of Medicine
Nurse Lead CNM3 in Antimicrobial Stewardship in St James's Hospital Carolyn O' Reilly joins us today to speak about her pilot role. Please leave us any feedback or send episode suggestions to icueducationteam@stjames.ie Enjoy the episode! Of note: This episode was recorded in January 2024
We all know what antimicrobial stewardship (AMS) is, but implementation in the community pharmacy space is something that is still developing. This podcast episode will empower listeners to recognize that there are small things that they can do to improve AMS in the community setting. The episode will also discuss how the Centers of Disease Control's core elements of outpatient AMS apply to practitioners in a community pharmacy setting. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.
Carbapenemase producers are a nightmare for clinicians. Not only are they resistant to carbapenems, a last resort β-lactam antibiotic, they are notorious for developing multidrug and pandrug resistances resulting in limited to no treatment options. In this episode of Communicable, hosts Angela Huttner and Thomas Tängdén sit down with Dr. David Paterson (National University of Singapore) and Dr. Souha Kanj (American University of Beirut Medical Center, Lebanon), two ID physicians from regions where carbapenem-resistant Enterobacteriaceae or CRE, and carbapenem-resistant Acinetobacter are widespread. The episode begins with the history and emergence of CRE and reviews current epidemiology, diagnosis (including the Ambler classification of β-lactamases) and treatment options. Lessons and insights from personal experiences are shared to reflect the current clinical challenges caused by carbapenem-resistant bacteria and the importance of infection prevention and control measures to mitigate further spread. This episode was edited by Kathryn Hostettler and peer-reviewed by Dr. Filippo Medioli of Policlinico di Modena, Italy. For more related content on the WHO Priority Pathogens List and new antibiotics in the pipeline, check out our previous episodes, Communicable E3 and E10 (see Literature).Literature Communicable E3 - The New WHO Priority Pathogens List: which bugs to target first? June 2024. https://communicable.transistor.fm/episodes/communicable-e3-the-new-who-priority-pathogens-list-which-bacteria-to-target-first Communicable E10 - Pipeline update: new antibiotics & other antimicrobials that you might actually use. Sep 2024. https://communicable.transistor.fm/episodes/communicable-e10-pipeline-update-new-antibiotics-other-antimicrobials-that-you-might-actually-use Wagenlehner FM, et al. Cefepime-Taniborbactam in Complicated Urinary Tract Infection. N Engl J Med 2024 Feb. doi: 10.1056/NEJMoa2304748 Cohn J, et al. Accelerating antibiotic access and stewardship: a new model to safeguard public health. Lancet Infect Dis 2024 Sep. doi: 10.1016/S1473-3099(24)00070-7 Timsit JF, et al. When should I start broad-spectrum antibiotics? Intensive Care Med 2024 Sep. doi: 10.1007/s00134-024-07654-7 Paterson DL. Antibacterial agents active against Gram Negative Bacilli in phase I, II, or III clinical trials. Expert Opin Investig Drugs 2024 Apr. doi: 10.1080/13543784.2024.2326028
On the verge of a post-antibiotic reality, there is an urgent clinical need for new antibiotics. Luckily, new candidates are in the pipeline and older agents are getting a second breath of life through combination therapy. In this episode of Communicable, host Erin McCreary invites Dr. Markus Zeitlinger of the University of Vienna (Austria) and scientific expert for the European Medicines Agency (EMA) and Dr. Michael Dudley, president and CEO of Qpex Biopharma, to discuss antimicrobials in the clinical development pipeline. Together they unpack how the WHO curate the priority list of pathogens and how companies adapt such lists into their antimicrobial development business plans. They also discuss the unique challenges and complexities of developing antibiotics, from return on investments and defining the ‘novelty' of an agent to the conundrum of balancing post-market approval and antimicrobial stewardship. Beta-lactamase inhibitors and oral carbapenems in the pipeline targeting ‘the big three' (Enterobacterales, Pseudomonas and Acinetobacter) are the primary focus. This episode was edited by Kathryn Hostettler and peer-reviewed by Dr. Benjamin Berinson of the Medical Centre Hamburg-Eppendorf (UKE), Germany. For more information on the WHO Priority Pathogens List and its 2024 update, check out our previous episode, Communicable E3 (see Literature). Literature Communicable E3 - The New WHO Priority Pathogens List: which bugs to target first? 17 June 2024. https://communicable.transistor.fm/episodes/communicable-e3-the-new-who-priority-pathogens-list-which-bacteria-to-target-first WHO Bacterial Priority Pathogens List, 2024: bacterial pathogens of public health importance to guide research, development and strategies to prevent and control antimicrobial resistance. Geneva: World Health Organization; 17 May 2024. https://www.who.int/publications/i/item/9789240093461 C. Le Terrier et al, NDM-9 resistance to taniborbactam. Lancet Infect Dis 23, 401-402 (2023). doi 10.1016/S1473-3099(23)00069-5 P. B. Eckburg et al, Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection. N Engl J Med 386, 1327-1338 (2022). doi: 10.1056/NEJMoa2105462 A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (PIVOT-PO). https://clinicaltrials.gov/study/NCT06059846 Meiji Seika Pharma Initiated the Global Phase III Clinical Trials of OP0595, a Novel beta-Lactamase Inhibitor for Combatting Antimicrobial Resistance (AMR). Tokyo: Meiji Seika Pharma Ltd; 26 April 2023. https://www.meiji.com/global/news/2023/pdf/230426_01.pdf
Only known to us since 2008, Candida auris is an emerging fungal pathogen spreading quickly around the world; alarmingly, it is most commonly found in healthcare settings. C. auris sets itself apart from other Candida species with its unique tolerance to high saline and temperature environments and propensity to develop antifungal resistances that promote its survival in hospitals and healthcare facilities. Hosts Emily McDonald and Navaneeth Narayanan are joined by fungal experts Dr. Jeffrey Rybak (St. Jude, Memphis TN) and Dr. Graham Snyder (UPMC, Pittsburgh PA) on their quest to better understand C. auris infections, the clinical challenges and knowledge gaps in C. auris research and discuss measures for prevention and containment on the levels of both the patient and the institution. The recent emergence of C. auris as a multidrug-resistant nosocomial pathogen and its global prevalence has raised more questions than answers. Why now? Why healthcare facilities? Does climate change play a role? Are humans to blame? Tune in to find out what the experts have to say on these questions, and stay to learn about the current therapies available, what is in the antifungal pipeline and how to approach treatment from a stewardship standpoint.This episode was produced by Angela Huttner, edited by Kathryn Hostettler and peer-reviewed by Dr. Claudio Neidhöfer of University Hospital Bonn, Germany.LiteratureSatoh K, Makimura K, Hasumi Y, et al. Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital. Microbiol Immunol. 2009 Jan;53(1):41-4. doi: 10.1111/j.1348-0421.2008.00083.xLee WG, Shin JH, Uh Y, et al. First three reported cases of nosocomial fungemia caused by Candida auris. J Clin Microbiol. 2011 Sep;49(9):3139-42. doi: 10.1128/JCM.00319-11Pfaller MA, Diekema DJ, Turnidge JD, et al. Twenty Years of the SENTRY Antifungal Surveillance Program: Results for Candida Species From 1997–2016. OFID. 2019 March;6(S1): S79–S94. doi: 10.1093/ofid/ofy358Lockhart SR, Etienne KA, Vallabhaneni S, et al. Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses. Clin Infect Dis. 2017 Jan 15;64(2):134-140. doi: 10.1093/cid/ciw691.Clancy CJ, Nguyen MH. Emergence of Candida auris: An International Call to Arms. Clin Infect Dis. 2017 Jan 15;64(2):141-143. doi: 10.1093/cid/ciw696Rybak JM, Cuomo CA, Rogers PD. The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris. Curr Opin Microbiol. 2022 Dec;70:102208. doi: 10.1016/j.mib.2022.102208
AABP Executive Director Dr. Fred Gingrich is joined by Dr. Eric Moore from Norbrook Laboratories, and Dr. John Sharpe, a practicing veterinarian in Kansas and a 2023 graduate of Kansas State University. This podcast is sponsored by Norbrook. Having the right antibiotics is critical to successfully treating seasonal diseases. Norbrook offers a variety of effective and value driven solutions such as Noromycin 300 LA, Norfenicol Injectable Solution, Tulieve Injectable Solution, Enroflox 100 Injectable Solution, and Cefenil RTU. To learn more, contact your Norbrook sales representative, your animal health distributor, or visit the Norbrook website. Sharpe discusses the seasonal variation of disease patterns he sees in his bovine practice and how these patterns influence antibiotic use as well as the producer's bottom line. He also shares his experiences with the implementation of GFI #263 which transitioned the remaining medically important over-the-counter antimicrobials to prescription status with veterinary oversight. We also discuss how he, as a veterinarian, walks through his decision-making processes for selecting an antimicrobial to treat an animal, herd or in protocol development. Moore provides some background on the frustration producers face when they experience treatment failure, how prevention is the most important part of a stewardship program, and what antibiotics do not do so that producers can understand how to use them properly and promote animal health. Listen to the previous podcast with Dr. Eric Moore on implementation of GFI #263 here. Make sure to visit the Norbrook booth at the AABP tradeshow at the upcoming 57th AABP Annual Conference in Columbus, Ohio, September 12-14, 2024.
Dr. Kerl is pleased to welcome Dr. Anne Kimmerlein to the podcast. Listen in as Dr. Kimmerlein, a veterinary epidemiologist with VCA Medical Operations, shares her journey in veterinary medicine and her role at VCA. In their conversation, they discuss the importance of the interconnectedness between people and their pets and the growing field of veterinary epidemiology. During the COVID-19 pandemic, Dr. Kimmerlein played a crucial role in providing guidance and protocols for hospitals and ensuring the safety of patients, clients, and associates. She also conducted a study on pets in households of people with COVID-19, finding that pets can get infected with the virus. Additionally, Dr. Kimmerlein discusses her work with the VCA clinical studies team, her involvement in antimicrobial stewardship, and her passion for shelter medicine.Visit our website: vcavoice.comAll episodes produced by dādy creative
Join us on War Docs as we welcome Army Physician MAJ Mary Ford, an infectious disease specialist and lead author of the acclaimed Military Medicine Journal's article of the year: Clinical Characteristics and Resistance Patterns of Pseudomonas aeruginosa Isolated From Combat Casualties https://pubmed.ncbi.nlm.nih.gov/34196358/ Listen in as MAJ Ford shares the impactful findings of her team's research on Pseudomonas aeruginosa in combat casualties, a topic of paramount importance to military health. Her personal journey into the infectious disease field, spurred by early curiosities and familial influences, and the progression of her military career make for a captivating story of dedication and passion. In this engaging conversation, we also tackle the critical subject of infection prevention and antimicrobial stewardship in the face of combat trauma. Hear about the vital role of simple measures, like hand hygiene, in combating infections, especially those caused by the antibiotic-resistant Pseudomonas aeruginosa. Discover how MAJ Ford's team utilized the Trauma Infectious Disease Outcomes Study to uncover that approximately 6% of combat trauma patients developed Pseudomonas infections. The implications of these findings are vast, offering significant advancements for clinical outcomes and infection control in military medical settings. Tune in for a deep understanding of how such research continues to shape practices and policies within the Department of Defense. Chapters: (00:02) Infectious Disease in the Military (07:12) Combat Trauma Infections and Pseudomonas Chapter Summaries: (00:02) Infectious Disease in the Military MAJ Mary Ford's research on Pseudomonas aeruginosa in combat casualties and its impact on military health, her personal journey into infectious disease, and the enduring need for ongoing research in the Department of Defense. (07:12) Combat Trauma Infections and Pseudomonas Infection prevention and antimicrobial stewardship are crucial in controlling Pseudomonas infections in combat trauma patients. Take Home Messages: In the context of military medicine, the issue of infections following combat trauma is a significant concern, with Pseudomonas aeruginosa identified as a noteworthy pathogen due to its prevalence in prolonged hospital stays and its intrinsic antibiotic resistance mechanisms. Infection prevention and antimicrobial stewardship are critical components in the management of combat trauma infections. Basic practices such as hand hygiene play a pivotal role in controlling the spread of infections and can have substantial impacts on patient outcomes. Research conducted through the Trauma Infectious Disease Outcomes Study (T-DOS) has revealed that about 6% of combat trauma patients develop Pseudomonas infections, which underscores the importance of understanding and addressing these infections to improve clinical practices and infection control protocols. Combat trauma patients with Pseudomonas infections often experience lengthy hospital stays and intensive care unit admissions, highlighting the need for robust infection prevention strategies in military healthcare settings to reduce the burden of these nosocomial infections. The fight against infections like Pseudomonas aeruginosa in military medicine is an ongoing challenge that requires continuous research and evidence-based practices to ensure the health and readiness of military personnel. Basic infection control measures remain foundational in mitigating infectious threats. Episode Keywords: Military Medicine, Infectious Disease, Pseudomonas aeruginosa, Combat Trauma, Antimicrobial Stewardship, Research, Clinical Practices, Infection Control, Military Health, Nosocomial Pathogen, Antibiotic Resistance, Retrospective Analysis, Prospectively Collected Data, Trauma Infectious Disease Outcomes Study, Clinical Outcomes, Infection Prevention, Military Medical Environments Hashtags: #wardocs #military #medicine #podcast #MilMed #MedEd #MilitaryMedicine, #PseudomonasAeruginosa, #CombatInfections, #InfectiousDiseases, #AntimicrobialStewardship, #WarDocsPodcast, #MilitaryHealthcare, #TraumaInfections, #InfectionPrevention, #ClinicalResearch Honoring the Legacy and Preserving the History of Military Medicine The WarDocs Mission is to honor the legacy, preserve the oral history, and showcase career opportunities, unique expeditionary experiences, and achievements of Military Medicine. We foster patriotism and pride in Who we are, What we do, and, most importantly, How we serve Our Patients, the DoD, and Our Nation. Find out more and join Team WarDocs at https://www.wardocspodcast.com/ Check our list of previous guest episodes at https://www.wardocspodcast.com/our-guests Subscribe and Like our Videos on our YouTube Channel: https://www.youtube.com/@wardocspodcast Listen to the “What We Are For” Episode 47. https://bit.ly/3r87Afm WarDocs- The Military Medicine Podcast is a Non-Profit, Tax-exempt-501(c)(3) Veteran Run Organization run by volunteers. All donations are tax-deductible and go to honoring and preserving the history, experiences, successes, and lessons learned in Military Medicine. A tax receipt will be sent to you. WARDOCS documents the experiences, contributions, and innovations of all military medicine Services, ranks, and Corps who are affectionately called "Docs" as a sign of respect, trust, and confidence on and off the battlefield, demonstrating dedication to the medical care of fellow comrades in arms. Follow Us on Social Media Twitter: @wardocspodcast Facebook: WarDocs Podcast Instagram: @wardocspodcast LinkedIn: WarDocs-The Military Medicine Podcast YouTube Channel: https://www.youtube.com/@wardocspodcast
Dr Katie Savin joins Ethics Talk to discuss their article, coauthored with Drs Laura Guidry-Grimes and Olivia Kates: “What Does Disability Justice Require of Antimicrobial Stewardship?” Recorded February 20, 2024. Read the full article for free at JournalOfEthics.org
All the internal medicine pharmacists are doing it, but what are they doing and is it working? Learn about this group's impact on antimicrobial stewardship. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1926.
Drs Lynne Fehrenbacher and Leah Leonard-Kandarapally join Ethics Talk todiscuss key roles of infectious disease pharmacists and many clinicians in antimicrobial stewardship. Read the full June 2024 issue for free at JournalOfEthics.org
This presentation was delivered by Karin Thursky as part of the Cure stream at CODA22, which took place in Melbourne in September 2022. For more information about the CODA Project go to: https://codachange.org/
Discover the crucial balance between caring for our feline companions and protecting our shared future on this enlightening episode with Casey Cazer and Amelia Safi to unpack the findings of their latest JAVMA articles. Prepare to be informed about the responsible use of the antibiotic cefovecin in cats, as we navigate through the divergent views of veterinarians and cat owners and address the broader implications of antimicrobial resistance. You'll gain insights into our discussions about the pressures vets face, such as client expectations and the financial reality of diagnostics, and hear firsthand how Amelia and Casey's research sheds light on the necessity for comprehensive guidelines and better information dissemination.This conversation isn't just for the vets and pet lovers; it reaches into the heart of community health. Together, we highlight the importance of considering the long-term impacts of antibiotic use, as we share our own stories and experiences in the ever-evolving field of veterinary medicine. Join us for a journey into the intersection of immediate care and sustainable health practices for our beloved pets.JAVMA article: Pathways to sustainable antimicrobial use in cats in: Journal of the American Veterinary Medical Association Volume 261 Issue 12 (2023) (avma.org)JAVMA article: Divergent veterinarian and cat owner perspectives are barriers to reducing the use of cefovecin in cats in: Journal of the American Veterinary Medical Association Volume 261 Issue 12 (2023) (avma.org)INTERESTED IN SUBMITTING YOUR MANUSCRIPT TO JAVMA ® OR AJVR ® ? JAVMA ® : https://avma.org/JAVMAAuthors AJVR ® : https://avma.org/AJVRAuthorsFOLLOW US:JAVMA ® : Facebook: Journal of the American Veterinary Medical Association - JAVMA | Facebook Instagram: JAVMA (@avma_javma) • Instagram photos and videos Twitter: JAVMA (@AVMAJAVMA) / Twitter AJVR ® : Facebook: American Journal of Veterinary Research - AJVR | Facebook Instagram: AJVR (@ajvroa) • Instagram photos and videos Twitter: AJVR (@AJVROA) / Twitter JAVMA ® and AJVR ® LinkedIn: https://linkedin.com/company/avma-journals
Join special guest, Dr. Swati Gaur, and your host, Dr. Diane Sanders-Cepeda, for this special episode of FMDA's Journal Club, Antimicrobial Stewardship & Quality. This session focused on the following Learning Objectives: Revisit current guidance and protocols for Antimicrobial Stewardship in our PALTC facilities. Discuss how we are tackling vaccinations as it relates to COVID, Flu and RSV in our PALTC facilities for both residents and staff. Describe the challenges that PALTC facilities have with the spread of drug resistant pathogens such as Candida auris. Provide examples of interdisciplinary approaches to combatting the over prescribing of antibiotics and share how this impacts the quality of care for PALTC residents. Review how our PALTC Facilities can work with their QIO to educate and implement policies on Antimicrobial Stewardship. Recorded: February 14, 2024 Guest Panelists: Amina Dubuisson, DNP, MBA/HCM, RN, LNHA, CDP; Deborah Franklin, MHA, NHA; and Toby Philpot Hosted by: Diane Sanders-Cepeda, DO, CMD Available Credit: The American Board of Post-Acute and Long-Term Care Medicine (ABPLM) issues CMD credits for AMDA On-The-Go and affiliate podcast episodes as follows: Claim CMD Credit
Today's episode of The SHEA Podcast discusses vancomycin and how antimicrobial stewardship programs should address its use. Our moderator is Mackenzie Keintz and our guests are Rebekah Moehring and Kimberly Claeys, two experts on the topic that represent the physician and pharmacy perspective of ASP programs. Listen as they discuss why vancomycin is a target for antimicrobial stewardship programs, strategies to target vancomycin use and safety, available alternatives, how to work with over prescribers, and lessons learned from our guests experiences targeting vancomycin use at their institution.
In this episode, we explore the transformative advancements in pork production with Banks Baker of PIC. Consumer expectations for high animal care standards, antimicrobial stewardship, and sustainable practices are reshaping the food industry. Innovative solutions and technologies are emerging to meet these demands, fostering sustainable food production. Gene editing plays a pivotal role in enhancing animal health and aligns with antibiotic stewardship goals in pork production. Baker discusses the potential impact of gene editing on preventing diseases like PRRS and how it parallels successful applications in human healthcare. Challenges and considerations in applying this technology to animal agriculture, particularly in protecting pigs from diseases, are also explored. PIC's groundbreaking development of a PRRS-resistant pig through gene editing is highlighted, offering broader implications for pig herd health and the significant reduction of antibiotic use. Navigating global regulatory systems presents challenges and opportunities for PIC, and Baker sheds light on the company's approach to gaining approvals worldwide. Join us in this episode as we delve into the future of pork production, where cutting-edge technologies and sustainable practices are reshaping the industry landscape.
In this episode, MVC2024 speaker Dr. Christy King joins us to talk about renewed interest in antimicrobial resistance and share a sneak peek into programming from next month's conference. --- Send in a voice message: https://podcasters.spotify.com/pod/show/fully-vetted/message
Anti-Microbial Stewardship Programs are critical to optimizing utilization, mitigating resistance, and improving patient outcomes. These programs are continuously refined, and recent updates to The Joint Commission standards provide an opportunity to enhance our approach. Dr. Ripal Jariwala, Infectious Diseases Clinical Pharmacist, and Assistant Clinical Professor at the University of California San Francisco, and Dr. Ethan A. Smith, Clinical Infectious Diseases Specialist at Ronald Reagan UCLA Medical Center, join host Gretchen Brummel to discuss the revised standards and implications for pharmacy. Guest speakers: Dr. Ripal Jariwala, PharmD, BCIDP, AAHIVP Infectious Diseases Clinical Pharmacist, and Assistant Clinical Professor UCSF Dr. Ethan A. Smith, PharmD., BCIDP Clinical Infectious Diseases Specialist Ronald Reagan UCLA Medical Center Host: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence Show Notes: [01:01-01:47] The guests background [01:48-02:58] Brief update of the recent changes to Antimicrobrial Stewardship [02:59-07:35] Interpreting the new EP-10 Joint Commission standard about financial and IT resources [07:36-11:23] The current landscape on FTEs to support antimicrobial stewardship [11:24-15:13] EP15 on evidence-based use of antibiotics considerations [15:14-18:27] How do you approach meeting the revised standard on data collection analysis and recording for EP20 [18:28 -21:23] Other standards besides the joint commission standards that people need to be aware of [21:24-23:34] Other related work going on in this space [23:35-26:54] More information or other resources to find those items about antimicrobial stewardship Links | Resources: Knowledge on the Go Podcast: Updates for Antimicrobial Stewardship Standards VHA directive 1031: Click here CDC Updates on Antibiotic Stewardship and Required Antimicrobial Use and Resistance Reporting – On Demand: CDC Updates OnDemand2023 document and Click here to play recording Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Android RSS Feed
Medicare's Hospital-Acquired Conditions Reduction Program (HACRP) is a value-based-purchasing program for Medicare that aims to link Medicare payments to a hospital's level of inpatient health care quality. Jacob Madden, Research Specialist, Program on Regulation, Therapeutics, and Law, Harvard Medical School and Brigham and Women's Hospital, and Christina Yen, MD, MBE, Medical Director of Antimicrobial Stewardship, Maine Medical Center, discuss how the HACRP works, how hospital-acquired conditions (HACs) affect hospitals' ability to care for patients, how a hospital's HAC score is calculated, what happened to the HACRP during the pandemic, and what a successful post-pandemic HACRP might look like. Jacob recently authored an article for AHLA's Journal of Health and Life Sciences Law about this issue.To learn more about AHLA and the educational resources available to the health law community, visit americanhealthlaw.org.
In this podcast, Julie Ann Justo, PharmD, MS, FIDSA, BCPS, discusses treatment of carbapenem-resistant Enterobacterales (CRE) infections, including:Burden of CRE infections in the United StatesMechanisms of resistanceChanging epidemiologyUse of rapid diagnostic testsIDSA guidance recommendations, including supporting dataApproach to designing treatment regimens, including weighing patient- and infection-related factorsFaculty:Julie Ann Justo, PharmD, MS, FIDSA, BCPSClinical Pharmacist Lead – Infectious DiseasesInpatient PharmacyDartmouth Hitchcock Medical CenterLebanon, New HampshireLink to full program: https://bit.ly/41a8Mj0Link to accompanying ClinicalThought commentary:https://bit.ly/4865T57Link to downloadable infographic: https://bit.ly/3t7NpT2
Priya Nori, MD, medical director of Antimicrobial Stewardship, at Montefiore Health System, joins to discuss US Antibiotic Awareness Week (November 18-24). Dr. Nori details the harms of antibiotic and anti fungal overuse, the steps health systems can take to help physicians use antimicrobials appropriately, and the holistic efforts that are needed to combat antimicrobial resistance. American Medical Association CXO Todd Unger hosts.
Antimicrobial resistance continues to be a public health threat across the globe. Recent updates to the Joint omission standards provide an opportunity to evaluate our current programs for improvements. Today's program looks at what two health organizations are doing to optimize antimicrobial utilization, mitigate antimicrobial resistance and improve patient outcomes. Joining Vizient's Jim Lichauer for this discussion are Michael Postelnick System Program Director of Antimicrobial and Diagnostic Stewardship at Northwestern Medicine and Lucas Schulz, Antimicrobial Stewardship Program Director and PGY1 and PGY2 for Infectious Disease at University of Wisconsin Health. Guest speakers: Michael Postelnick, RPh BCPS AQ-Infectious Diseases System Program Director, Antimicrobial and Diagnostic Stewardship Northwestern Medicine Lucas Schulz, PharmD, BCIDP Clinical Manager, Acute Care Services Residency Program Director – PGYI and PGY2 Infectious Diseases University of Wisconsin Health Moderator: Jim Lichauer, PharmD, BCPS, FASHP Senior PI Program Director, Pharmacy Vizient Show Notes: [1:10] The Joint Commission and CMS updates are driving antimicrobial stewardship programs (ASP) forward [3:50] EP 10 criteria to determine necessary resources to operate the stewardship program effectively and ensure that the resource allocation matches the determined needs [5:20] EP 12 is revised to specifically require competency-based training for medical staff [7:35] EP 20 recommends reporting ASP data to hospital leadership and prescribers [9:45] Joint Commissions new standards include ambulatory care [13:25] CMS rules for infection prevention and antimicrobial stewardship (CMSQSO-22-20) Links | Resources: Contact Knowledge on the Go: picollaboratives@vizientinc.com Subscribe Today! Apple Podcasts Spotify Google Podcasts Android RSS Feed
In this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections involving Pseudomonas aeruginosa with difficult-to-treat resistance, including: Mechanisms of β-lactam resistanceEffect of resistance mechanism on susceptibility to antipseudomonal agent2023 IDSA guidance recommendations Activity against newer antipseudomonal β-lactams in the United StatesThe latest clinical data by antimicrobial regimen: - Ceftolozane/tazobactam - Ceftazidime/avibactam - Imipenem/cilastatin/relebactam - CefiderocolApplying antimicrobial stewardship principlesProgram Director:Trevor Van Schooneveld, MD, FSHEA, FACP Professor, Division of Infectious DiseasesProgram Director, Infectious Diseases FellowshipMedical Director, Antimicrobial Stewardship ProgramUniversity of Nebraska Medical CenterOmaha, NebraskaFaculty:Emily Heil, PharmD, MS, BCIDP, AAHIVPAssociate ProfessorDepartment of PharmacyUniversity of Maryland School of PharmacyID Clinical Pharmacy SpecialistUniversity of Maryland Medical Center|Baltimore, MarylandLaila Woc-Colburn, MDAssociate ProfessorDivision of Infectious DiseasesEmory University School of Medicine Atlanta, GeorgiaContent based on a CME program supported by an educational grant from Merck & Co., Inc., Rahway, NJ, USA.Follow along with a downloadable slideset at: https://clinicaloptions.com/CE-CME/infectious-disease/cmv-prevention-in-sot-recipients/26139Link to full program: https://bit.ly/40HyvPy
In this episode, Lillian Abbo, MD, MBA, FIDSA, discusses appropriate antimicrobial selection for managing uncomplicated UTIs, including:Balancing discrepancies in available guidelines Individualizing antimicrobial selection based on patient characteristics and local resistance patterns Incorporating tools, like antibiograms, into daily practice Being a good steward of currently available antimicrobial agents Planning ahead for emerging therapies for uncomplicated UTIsPresenter:Lillian Abbo, MD, MBA, FIDSAAssociate Chief Medical Officer Infectious DiseasesJackson Health SystemProfessor of Clinical Infectious DiseasesUniversity of Miami Miller School of MedicineMiami Transplant InstituteMiami, FloridaFind other program activities here: “Uncomplicated” Doesn't Mean Easy: Recognizing the Burden and Preventing Treatment Failure of Uncomplicated UTIsSlides on “Uncomplicated” Doesn't Mean Easy: Recognizing the Burden and Preventing Treatment Failure of Uncomplicated UTIsPodcast 1: Burden on Uncomplicated Urinary Tract InfectionsPodcast 3: When Things Get Complicated: Managing uUTIs in Acute CareClinicalThought: Not Always an Easy Task: Antimicrobial Stewardship for Uncomplicated UTIs
In this episode, Lilly C. Lee, MD, SM, FACEP, FAAEM, discusses the best practices in management of uUTI in the emergency department, including:Patient triageDiagnostic stewardshipInterdisciplinary careStrategies to overcome treatment barriersPresenter:Lilly C. Lee, MD, SM, FACEP, FAAEMChief of Emergency MedicineJackson Memorial HospitalFlorida Poison Information CenterRoxcy Bolton Rape Treatment CenterAffiliated Assistant Professor of SurgeryDeWitt Daughtry Family Department of SurgeryLeonard M. Miller School of MedicineUniversity of MiamiMiami, FloridaFind other program activities here: “Uncomplicated” Doesn't Mean Easy: Recognizing the Burden and Preventing Treatment Failure of Uncomplicated UTIsSlides on “Uncomplicated” Doesn't Mean Easy: Recognizing the Burden and Preventing Treatment Failure of Uncomplicated UTIsPodcast 1: Burden on Uncomplicated Urinary Tract InfectionsPodcast 2: Updates in Antimicrobial Selection for uUTIsClinicalThought: When Care Gets Complicated: Uncomplicated UTI Management in Acute Care Settings
Episode Notes In this special episode of Breakpoints, pharmacist Hailie Uren joins Dr. Erin McCreary (@ErinMcCreary) to talk about the current practice of medicine in Ukraine, including the extremely drug-resistant war wound infections she frequently encounters. You won't want to miss this amazing insight, and can support UK-Med in Ukraine here: https://www.uk-med.org/donate-now Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ SIDP welcomes pharmacists and non-pharmacist members with an interest in infectious diseases, learn how to join here: https://sidp.org/Become-a-Member Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, Stitcher, Google Play, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/ Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.
In response to the global burden of antimicrobial resistance (AMR) and the critical role antimicrobial stewardship plays in optimizing antibiotic use and reducing the subsequent emergence of AMR, Antimicrobial Agents and Chemotherapy is excited to add a new section to the journal focused on antimicrobial stewardship studies. Combatting the devastating burden of AMR requires novel, multipronged approaches from clinicians and scientists alike. Launching this new section is an important step in disseminating cutting-edge research that will have notable implications in the global fight against antimicrobial-resistant pathogens. Topics discussed: The role of antimicrobial stewardship in preventing emerging of resistance. The types of high-quality manuscripts that AAC is seeking in this area. Encourage excellence in antimicrobial stewardship research. Guests: Pranita Tamma, MD MPH, Associate Professor of Pediatrics Director, Pediatric Antimicrobial Stewardship Program, Johns Hopkins University, Baltimore MA, Editor AAC. Ryan Shields PharmD, MS. Associate Professor of Medicine, Co-Director, Antibiotic Management Program, University of Pittsburgh, Pittsburgh, PA. Editor AAC. This episode is brought to you by the Antimicrobial Agents and Chemotherapy journal available at aac.asm.org. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/membership to sign up. Visit journals.asm.org/journal/aac to browse issues and/or submit a manuscript.
Dr. Deborah Milito: linkedin.com/in/deborah-milito-32a28156 Dr. Scott Stewart: linkedin.com/in/scott-stewart-34973870 Dr. Tamara Ruggles: linkedin.com/in/tamara-ruggles-491882251 CDC Core Elements of Antibiotic Stewardship for Nursing Homes: https://www.cdc.gov/antibiotic-use/core-elements/nursing-homes.html ASCP Antimicrobial Stewardship Toolkit: https://www.med-pass.com/antimicrobial-stewardship-toolkit-for-long-term-care-with-usb-flash-drive.html FDA Advisory Committee Calendar: https://www.fda.gov/advisory-committees/advisory-committee-calendar ACIP meeting information: https://www.cdc.gov/vaccines/acip/meetings/index.html Candida auris: https://www.fda.gov/media/141083/download Updated guidelines for Asymptomatic Bacteriuria: https://www.idsociety.org/practice-guideline/asymptomatic-bacteriuria/ Clostridiodes difficile clinical practice guidelines: https://www.idsociety.org/practice-guideline/clostridioides-difficile-2021-focused-update/ Community-Aquired Pneumonia guidelines: https://www.atsjournals.org/doi/full/10.1164/rccm.201908-1581ST?role=tab Please e-mail questions, comments, and funny pharmacy jokes to ltcpharmacypodcast@gmail.com. We would love to hear from you!
In this episode, Kyle Molina, PharmD, BCIDP, provides an overview of treatment of skin and soft tissue infections (SSTIs) and challenges in practice. Listen as he gives perspectives on:Guideline recommendations for treatment of purulent and nonpurulent SSTIsLogistical challenges with IV and oral antibioticsPros and cons of various locations of careData supporting the safety and efficacy of long-acting lipoglycopeptides for treatment of SSTIsUse of long-acting lipoglycopeptides in special populations of interest, including patients with obesity, diabetes, and injection drug useOverall place in therapy of long-acting lipoglycopeptides for SSTIs Faculty:Kyle Molina, PharmD, BCIDPInfectious Diseases Clinical PharmacistScripps Green HospitalLa Jolla, CaliforniaLink to full program: CCO: https://bit.ly/3J4mg8hProCE: https://bit.ly/3P0vB4E
Episode Notes Drs. Zack Nelson (@zacroBID), Alison Dittmer, and Michael Pulia (@DrMichaelPulia) join Dr. Jillian Hayes (@thejillianhayes) to discuss the ins and outs of antimicrobial stewardship in one of the busiest parts of the hospital: the emergency department! Tune in for a discussion on communication considerations in the ED, the role of lipoglycopeptides for common gram-positive syndromes, and a rapid-fire round discussing common stewardship interventions. This podcast was supported by an educational grant from Melinta Therapeutics. References: Pulia M, et al. Antimicrobial Stewardship in the Emergency Department. Emerg Med Clin N Am 2018;36(4):853-872. doi: 10.1016/j.emc.2018.06.012. PMID: 30297009. Rech, Megan A et al. “PHarmacist Avoidance or Reductions in Medical Costs in Patients Presenting the EMergency Department: PHARM-EM Study.” Critical Care Explorations 2021;3(4):e0406. doi:10.1097/CCE.0000000000000406. PMID: 33912836. Sacdal JPA, Cheon E et al. Oritavancin versus oral antibiotics for treatment of skin and skin structure infections in the emergency department. Am J Emerg Med 2022;60:223-224. Jenkins TC, Jaukoos JS et al. Patterns of use and perceptions of an institution-specific antibiotic stewardship application among emergency department and urgent care clinicians. Infection Control and Hospital Epidemiology 2020;41:212-215. Dretske D, Schulz L, Werner E, Sharp B, Pulia M. Effectiveness of oritavancin for management of skin and soft tissue infections in the emergency department: A case series. The American Journal of Emergency Medicine 2021;43:77-80. doi: 10.1016/j.ajem.2021.01.050. PMID: 33545550. Paul M, Pulia M, Pulcini C. Antibiotic stewardship in the emergency department: not to be overlooked. Clin Microbiol Infect 2021;27(2):172-174. doi: 10.1016/j.cmi.2020.11.015. PMID: 33253938. Baxa J, McCreary E, Schulz L, Pulia M. Finding the niche: An interprofessional approach to defining oritavancin use criteria in the emergency department. Am J Emerg Med. 2020;38(2):321-324. doi:10.1016/j.ajem.2019.158442. Pulia MS, Hesse S, Schwei RJ, Schulz LT, Sethi A, Hamedani A. Inappropriate Antibiotic Prescribing for Respiratory Conditions Does Not Improve Press Ganey® Patient Satisfaction Scores in the Emergency Department. Open Forum Infect Dis 2020;7(6): ofaa214. doi:10.1093/ofid/ofaa214. Pulia MS, Lindenauer PK. Annals for Hospitalists Inpatient Notes - A Critical Look at Procalcitonin Testing in Pneumonia. Ann Intern Med. 2021;174(6):HO2-HO3. doi:10.7326/M21-1913. Redwood R, Knobloch MJ, Pellegrini DC, Ziegler MJ, Pulia M, Safdar N. Reducing unnecessary culturing: a systems approach to evaluating urine culture ordering and collection practices among nurses in two acute care settings. Antimicrob Resist Infect Control. 2018;7. doi:10.1186/s13756-017-0278-9. Pulia MS, Schwei RJ, Hesse SP, Werner NE. Characterizing barriers to antibiotic stewardship for skin and soft-tissue infections in the emergency department using a systems engineering framework. Antimicrob Steward Healthc Epidemiol. 2022;2(1):e180. doi:10.1017/ash.2022.316. May L, Gudger G, Armstrong P, et al. Multisite exploration of clinical decision making for antibiotic use by emergency medicine providers using quantitative and qualitative methods. Infect Control Hosp Epidemiol. 2014;35(9):1114-1125. doi:10.1086/677637. May L, Cosgrove S, L'archeveque M, et al. A Call to Action for Antimicrobial Stewardship in the Emergency Department: Approaches and Strategies. Ann Emerg Med 2013;62(1):69-77.e2. doi: 10.1016/j.annemergmed.2012.09.002. PMID: 23122955. Schoffelen T, Schouten JA, Hoogerwerf JJ, et al. Quality indicators for appropriate antimicrobial therapy in the emergency department: a pragmatic Delphi procedure. Clin Microbiol Infect 2021;27(2):210-214. doi: 10.1016/j.cmi.2020.10.027. PMID: 33144204. Yadav K, Stahmer A, Mistry RD, May L. An Implementation Science Approach to Antibiotic Stewardship in Emergency Departments and Urgent Care Centers. Academic Emergency Medicine 2020; 27(1):31-42. doi: 10.1111/acem.13873. PMID: 31625653. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ SIDP welcomes pharmacists and non-pharmacist members with an interest in infectious diseases, learn how to join here: https://sidp.org/Become-a-Member Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, Stitcher, Google Play, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/ Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.
Deverick John Anderson, MD, MPH, professor of medicine at Duke University and director of the Duke Center for Antimicrobial Stewardship and Infection Prevention, discusses the evidence and appropriate strategies used in the prevention of surgical site infections with JAMA Associate Editor Anthony Charles, MD, MPH. Related Content: Surgical Site Infection Prevention