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Best podcasts about auu

Latest podcast episodes about auu

Focus PREVIDENZA
ASSEGNO UNICO: Le novità INPS per i cittadini stranieri

Focus PREVIDENZA

Play Episode Listen Later Jul 26, 2022 3:27


Anche i cittadini stranieri possono richiedere l'assegno unico e universale per i figli a carico, ma per farlo, devono rispettare determinate condizioni.

Focus PREVIDENZA
ASSEGNO UNICO: Il nuovo servizio su APP INPS mobile

Focus PREVIDENZA

Play Episode Listen Later Jul 25, 2022 2:10


Si tratta di una novità INPS, che infatti, tramite il messaggio n. 2925, fa sapere che è ora disponibile proprio sull' app Inps mobile, un nuovo servizio dedicato ai dispositivi mobili per l'invio delle domande.

Caffe 2.0
2473 Assegno unico universale - come si compila e quali errori comuni non commettere

Caffe 2.0

Play Episode Listen Later Jun 14, 2022 8:03


Facile chiederlo, ma anche facile sbagliare.Ecco come fare e a cosa prestare attenzione.sito auu.gov.itSostienici con patreon.com/caffe20 e segui la linkografia : auu assegno unico su caffe20.it/link

The Guys Review
Hubie Halloween

The Guys Review

Play Episode Listen Later Oct 4, 2021 98:10


Hubie Halloween Welcome to The Guys Review, where we review media, products and experiences.  **READ APPLE REVIEWS/Fan Mail**Mention Twitter DM group - like pinned tweetRead emails  Hubie Halloween Directed by: Steven Brill (Also directed Little Nicky and Mr. Deeds, among others) Starring:  Adam SandlerKevin JamesJulie Bowen (also in Happy Gilmore as Virginia Venit)Ray LiottaRob SchneiderJune SquibbKenan ThompsonShaquille O'Neal Released: October 7, 2020 Budget: No info, part of the Netflix deal with Adam Sandlers Happy Madison Productions. The original deal Sandler inked $250 million with Netflix in 2014 to produce six films for the streaming service, with Hubie Halloween being #6. It was announced in Jan 2020, Sandler and Netflix extended their deal for 4 more movies. Box Office: Ratings:   IMDb 5.2/10 Rotten Tomatoes 54%Metacritic 53% Google Users 79%  First time you saw the movie? Plot:It opens at Westford State Mental Hospital with Hal from Happy Gilmore finding the psycho is on the loose. Cutting to Salem, we see Hubie biking through the town, being friendly, but everyone being a dick to him, throwing eggs at him. A slow motion viewing of Violet Valentine, sends Hubie flying over a car. Hubie is working at the meat counter, Mr. Landofla is called and calls him Pubie. Generally giving him shit, when, with the help fo the other employee, they jump scare Hubie with the lambs head in the meat case. Everyone laughs. Sgt Downy is watching videos in his cruiser, like all cops do, and he gets a call that Richard Hartman escaped the psych ward. Its revealed that Downy testified against him, when Hubie startles him, telling him the O'Doyle kid was buying a bunch TP. Hubie obviously is a worry wort as Downy tells him not to bother him, a gang of kids with scream masks chase after him, and he expertly dodges everything, including flaming dog shit. Hubie takes a tumble and they ride off with an "O'Doyle Rules"... Hubies new neighbor Walter Lambert helps him up, and some back story about his swiss army thermos. We see how over done his house is for halloween. He walks in and is scared by a decoration. Hubies mom is wearing a 'boner doner' shirt and they discuss Mr. Lambert. His mom comments how hard Hubie works to help others, but that he needs to stand up for himself. In his room, Hubie is reminiscing about high school, and see that Sgt. Downy and Violet were a couple, and he regrets not being brave enough to ask her out. He gets scared, again, and busts his window with the year book, and cleans it up with the thermos. Outside the house, we see the escaped inmate peeing in front of Hubies house. S:-Regarding him getting scared so much... Why is halloween his favorite holiday? Also, how can you get scared by decorations that you obviously put up?-The kid who plays Deli Mike was supposed to be played by Cameron Boyce, but he died from epilepsy complications days before filming began. At Violets house, shes watching Wake Up Boston and all the anchors are dressed at Harley Quinn, they interview the Salem mayor. Sgt Downy is investigating a pig that was killed, and it almost descends into ta domestic dispute. At the salem museum, the janitor is making fun of Hubie in front of Violet, and even the museum worker throws away his word searches. She introduces him to her children, including foster children, and Hubie tells that his ancestors were in the Salem witch trials, where Chris was a judge. She discloses she and Sgt. Downy are divorced, and she makes it VERY obvious shes interested. She mentions something off about a Lambers tombstone, and Hubie goes to investigate. There is of course a funeral going on right next to the grave he's looking for. As Hubie digs, he's throwing dirt on the attendants. He finds Walters grave says born in 1661, but no death date. We learn it was Landolfas dad who died... He begins to apologize, but it was a rouse to push Hubie in the grave. When the gravedigger starts to throw dirt, he says hes down there, it scares the digger, he grabs his chest, and falls in, on to Hubie...which would be the only way Trey could get someone on top. Riding his bike down the street, ducking random objects thrown at him, Hubie finds Mr. Lambert boarding up his house and they have a very strange conversation about age. At the school, O'Doyle gives one of Violets foster kid a hard time, and a teacher sticks up for her. Hubie comes to give a halloween safety speech, wearing his pee stained sheet. He starts to explain his GHOST acronym, and he gets scared by a kid in costume, so they all start throwing food at him. At a coffee shop, Violets son Tommy tries to hit on the barista, and she tells him about the halloween party. A confusing phone call to the radio station, and at Violets house, she tells her kids Hubie is the nicest guy in town, and that niceness matters. Halloween starts, and the escaped inmate ominously puts on a pig mask. S:-The mayors jacket is like the mayors from jaws-The two girls that are Violets kids are Adam Sandlers real life kids-I get the comedy...but why dig up a grave like that when there's a funeral going on right next to it. Come back in an hour. Jeez.  As Hubie leaves, his mom implores him to stay. As he rides, he saves a cat, and Violet threatens the woman to thank Hubie... Which she still doesn't. Hubie almost asks Violet out, and shes visibly disappointed. We see a girl who is about to take more than one piece of candy, and he starts to teach her a lesson about the honor system. Mr. Hennessey approaches and gives him more crap, and the others laugh at him. He tells him he heard weird noises coming from Mr. Lamberts house, so Hubie goes to investigate. Hearing the noises, Hubie racks up a B and E, and gets in the house. Searches for him, he falls into the basement and finds things leading him to believe Mr. Lambert may have a dog... He finds Walter, but he takes off. At the police station, Downy is still talking to the farmers, when Hubie interrupts. Downy tells him about the AUU, Auxiliary Undercover Unit. Hes not to contact anyone, and to keep a log of what he finds, and drop it in the trash can across the town hall, and he agrees just like Tuckers captain told him. Cookie builds a candy tower to donate, as Hubie suggested, but she can't find Tommy, so she goes to Danielle for help. We find Tommy at the halloween party. Deli Mike spikes the punch, when the barista finds Tommy and they flirt. Hubie enters and starts pooping the party. They threaten to kill him and he goes into a boner tirade. Deli Mike hatches a plan to scare Hubie in the corn maze. Tommy and the barista go to tell Hubie its a prank. Mike scares barista Megan, and he punches Tommy. We see someone/something approach Mike and he looks scared, and it cuts to Hubie finding Tommy and Megan. Walking through the maze, he finds Mike tied up and gagged. and he's just yanked into the corn. According to the voice over it's 9pm. Hubie tries to contact Downy, but he ignores him. Violet arrives at the diner misses a call from Danielle. At the drive in the Hennessys comment how impressive it is how long Hubie has been a loser, and hatch an idea to scare him. Mrs. Hennessy approaches Hubie and tells him about a scary old car. As he approaches, the lights come on, the engine starts, and it starts to approach him, he sees it's a headless driver, and he runs scared. The top drops and the kids in the scream masks start throwing eggs at him, he uses a grapple hook to get away, and they all laugh at him. Hubie encounters Walter, who he asks if he's a werewolf, and Walter turns and runs. At a city party, the mayor tells Downy they're not cancelling any of the activities because of a lost kid. The girls are wondering around looking for Tommy and encounter the guy in the pig mask. Hubie at the diner, talks with Violet about purpose, as he mixes soups in his thermos. She offers him some chardonnay, complements him and calls him a hero. The Hennessys are driving and laughing at Hubie when they encounter something in the road. He gets out to move what turns out to be be a scare crow, and he vanishes. Mrs. Hennessy gets out calling for him, and she's yanked away. S:-If Violet is SO into Hubie, why doesn't she ask him out? We're not kids anymore... The best part about being an adult, is we can do what we want. For kids, I do think the guy should ask the girl...but after a certain age... fuck it. who cares?-Seems like a pretty killer halloween party for all the underage kids to be drinking at... obviously someone had to know what was going on?-With everyone out trick or treating, at the drive in, who is home to give out candy.-Where did the old car come from?-Any pranks on people when you were younger? Tp yards, fork, anything like that?  Hubie is riding his bike looking for Danielle and Cookie, dodging objects thrown at him. Hubies mom looks at how people have vandalized her yard when Walter comes running by. He handcuffs himself to his fridge when the pig mask guy arrives and says they need to talk. Tommy and Megan are looking for the girls when Hubie arrives with them. Hubie tells them to be safe, that he's going to protect the city. In the bathroom, he hears a dog howl and thinks its Walter. He finds a dog that takes off into a haunted house. He goes through the house, terrified. Londalfa comes out of the haunted house with the teacher from earlier, and starts hitting on her. Hubie finds the dog, and tries to throw a silver bullet at it, but it eats it instead. Outside, Londolfa is called out for hitting on her, and the dog turns out to be hers. He hears Hubie, and goes in the house to scare Hubie. As he goes to scare him, he's yanked into the darkness. The mayor, officer Downy, Hubie and a few others gather and complain nothing has been done, Downy says nothing else planned is going to happen. Hubie tells them about his werewolf theory. Downy calls in the station to have someone check on Walter, when the other officer tells him Walter and Richie turned themselves in 45 minutes ago and we find out Walter and Richie are roommates at the mental hospital. Walter, who is Nick Hudson, broke out a month ago, and Richie broke out to find him. So with those two in custody, they turn on Hubie accusing him of making the people who are mean to him making them disappear. Hubie runs away, through the woods, still getting things thrown at him, when he approaches the radio station. Inside, what has sounded like a woman voice over/DJ Aurora, turns out to be Shaq. Hubie is looking for some advice, and the DJ and his wife tell him about the only other person who calls in more than him, and that he always dedicates a special song to Hubie and they said they were going to do something special for Hubie on halloween, after drinking too much chardonnay. Downy arrives and Hubie tells him Violet is the only person who is nice to him. They set up a sting. S:-What time is it at the haunted house? Who does all that on halloween night-The sliver bullet, that shit was plastic. Who would walk around with silver bullets like that?-WTCH is a radio station from Shawano, Wisconsin-Was the "wife" a guy or a girl? Violet approaches and Hubie, and he immediately calls for back up. Downy calls the number who called the radio station, but the phone doesn't ring, and they find the cell phone is in Hubies house. Hubie and Violet confess their love for each other, and Hubie steals a boat for some reason. At Hubies house, he finds his mom with a glass of chardonnay. Hubie asks if hes her special someone. He sees Landolfo in the back yard, goes out and sees all the missing people. Hubies mom tells him why she did what she did, and starts adding gas to the wood. As she strikes a match and they all ask for help, Hubie remembers how all of them have been mean to him, laughed at him, all the punishment he's taken, when he remembers what Violet said about him being a hero, he slings the last bit of soup and puts out the match. The cops arrives, and they still give him shit even though he just saved them. Hubies mom tells them all off, and calls them all out...and they explain why they're all mean to him. Pressure to be cool, hair loss, lack of sexual fulfillment, fake dyslexia because he's just dumb. Hubies mom explains why she did what she did, and she yells "Frankenstein" and runs off. We also find out Walter killed the pig from early on. Hubie wishes Violet happy halloween and share a kiss through the tv. 1 year later, they kiss and the kids show their costumes for Halloween, Father Dave, Richie, Officer Downy and wolfman Walter. Hubie is shown to be the mayor with his sash, he made thermos' for the kids, as he rides to the city events, we see the kids and they are nice to Hubie. Hubie pranks them instead, and everyone is shown to be nice and wave to Hubie. Credits roll with Hubie screaming and outtakes. S:-The reporter that shows up at the end is Adam Sandlers wife-All in all, kinda funny, I like the references to other Sandler movies. I hope they do one where they bring in a bunch of other Sandler characters.  Web: https://theguysreview.simplecast.com/EM: theguysreviewpod@gmail.comIG: @TheGuysReviewPodTW: @The_GuysReviewFB: https://facebook.com/TheGuysReviewPod/ Please, rate and review us wherever you get your podcasts from!! Thank you,-The Guys

SF Live
Gold Race Is Heating Up In Arizona

SF Live

Play Episode Listen Later Jun 22, 2021 23:56


On #SFLive Ep 197 we speak with Derek Macpherson, CEO of Gold79 Mines Ltd. (TSX.v: AUU) about exploring for gold in a hot area of Arizona, their plans for the summer & more. #GOLD #ARIZONA MAKE SURE TO SUBSCRIBE TO OUR CHANNEL & HIT THE ALERT BUTTON For more information, please visit: https://gold79mines.com/ Also, follow us on www.twitter.com/soarfinancial - make sure to follow us & click on the bell icon! ►► Follow Us! ◄◄ Twitter: http://twitter.com/soarfinancial Instagram: https://www.instagram.com/soarfinancial/ Facebook: https://www.facebook.com/soarfinanctial/ Website: http://www.soarfinancial.com SF Live is a new format by Soar Financial Partners. The goal is to give short company updates and more importantly get investors engaged directly with the companies. Intro Music: "Summer" by Bensound.com Disclaimer: Unless specifically disclosed, all information available on Soar Financial and its affiliates or partners should be considered as non-commercial in nature. None of the content produced by Soar Financial should be considered an endorsement, offer or recommendation to buy or sell securities. Soar Financial is not registered with any financial or securities regulatory authority in Canada, the US, Europe, or the UK, and does not provide, nor claim to provide, investment advice or recommendations to any consumer of the content that Soar Financial produces and publicizes. Always do your own due diligence and/or consult a qualified legal, tax, or investment professional if personal advice is deemed necessary. Soar Financial and its related companies (including its directors, employees, and representatives) or a connected person may hold equity positions in securities detailed in communications. When this occurs a disclosure will be made. Disclosures on social media will be made using the hashtag #coi (short for conflict of interest). Soar Financial, its affiliates, and their respective directors, officers, employees, or agents expressly disclaim any liability for losses or damages, whether direct, indirect, special, or consequential, or other consequences, howsoever caused, arising out of any use or reproduction of this site or any decision made or action taken in reliance upon the produced content of Soar Financial, whether authorized or not. By accessing Soar Financial's content, each consumer of Soar Financials content releases Soar Financial, its affiliates, and their respective officers, directors, agents, and employees from all claims and proceedings for such losses, damages, or consequences. Soar Financial may provide content on third-party sites and we disclaim any responsibility for the content of any information posted on such other websites. #mining #exploration #debt #financing #investing #investment #stocks #goldprice #inflation #wealth #FED #moneyprinting #silver #gold #wallstreetbets #silversqueeze #wsb #hold

Andreas und Umberto
#17 Die Schönen und das Beef

Andreas und Umberto

Play Episode Listen Later Sep 6, 2020 32:21


Folge Nummer 17 beginnt leider dramatisch. AuU haben ihren ersten Beef seit 15 Jahren und dann auch noch live im Podcast. Ricky, Jazzy und Lee finden das zu peinlich. Ähnlich peinlich sind eigentlich nur die Skills von Michael und Stefan an der Friteuse. Denn weder Sushi, Falafel oder Bierteig wollen gelingen von daher lässt man lieber gleich die Profis ran und geht zu Veggie Bros. Was ihr nie mit Wasser löschen solltet ist aber das Feuer das zwischen Andreas und Umberto lodert. Fett und Wachs hingegen sind ungefährliche Löschopfer, das bekommt man bereits mit 7 Jahren eingebläut. Bleiben wir beim Thema Küche. Stefan hat in den letzten 2 Wochen mehrere Küchen demontiert und ist schockiert was er dabei für archäologische Funde gemacht hat. Da geht Michael lieber ins emotionale Zölibat und besiegt seinen inneren Schweinehund am Tag mehrfach während Stefan zusammen mit seinem Schweinehund gerne auch mal 1-2 Bier trinkt. Gute Sachen werden richtig scheiße wenn man dabei dringend aufs Klo muss, das trifft nicht nur auf Star Wars zu sondern auch auf Pärchen die sich zusammen Farbfächer auf dem Baumarktparkplatz zu Gemüte führen. Warum Stefan so langsam ein Ruf als Pflanzenmörder nachgesagt wird und Michael ungern zugibt das er auf Schuppenshampoo scheißt erfahrt im Erfolgspodcast aus Würzburg für Hörer*innen mit Niveau.

De Wijze Woestenij
Maxim Hartman: ‘Als ik mijn diepste pijn toelaat ga ik dood van verdriet’

De Wijze Woestenij

Play Episode Listen Later Jun 18, 2019 69:09


Maxim Hartman leert ons tegen wil en dank waarom zijn woestheid het vaak wint van wijsheid, waarom porno slecht is voor je fantasiespier en waarom het verwoorden van je kwetsbaarheid een goed idee kan zijn. En o ja, waarom het zo jammer is dat therapie door middel van stokslagen verboden is. Ik had het natuurlijk kunnen weten toen ik Maxim vroeg voor deze podcast. Maxim is naast kunstenaar en media-ontregelaar ook graag een verbale beul, en laat werkelijk niets van me heel in het eerste deel van het gesprek, ik met mijn wijsneuzige ideetjes en mijn grote mond. Maar goed, in het tweede gedeelte van het gesprek krijgen we toch meer te zien van de zorgzame, uiterst gevoelige en, jawel mensen, kwetsbare man die achter deze bekvechter schuilgaat; en ga ik beter begrijpen waar zijn dwangmatig dominante, soms ronduit agressieve houding (niet slaan Maxim!) vandaan komt. Is het iemand om van te houden? HELL YEAH! Misschien is hij niet altijd even ‘wijs’ in de traditionele zin van het woord, maar kom er maar eens om, iemand die zo eigen is, creatief en radicaal eerlijk; en tegelijkertijd zo onuitstaanbaar. En, als laatste, even tussen jou en mij: Maxim heeft natuurlijk uiteindelijk een heeeel klein hartje! (Auu!..sorry Maxim, sorry auauauu!!)

Upper Hand Podcast
Upper Hand Sports EP 46: FORCE Basketball

Upper Hand Podcast

Play Episode Listen Later Jan 23, 2019 31:31


Randy Orisma the founder of FORCE Basketball and Stephen Schwarz the Director of Business Operations join the Upper Hand Sports Pod. FORCE Basketball is New York City's fastest growing Youth basketball program. They give student-athletes an opportunity to develop their talents and skills with some of the most experienced former players and coaches in the AUU circuit. Powered by SuperMe Performance, FORCE Basketball benefits from the guidance and expertise of a comprehensive strength and conditioning program specifically tailored to youth basketball athletes by certified trainers- improving overall athleticism and reducing the likelihood of injury. Force prepares student-athletes for the high demands of high school, collegiate and professional basketball.

Burtu Burvis
Dosimies dabā (K. Tolla, I. Sokolovski). Ko dara Runcis Francis (U. Auseklis)

Burtu Burvis

Play Episode Listen Later Jun 16, 2018 38:16


Bērnu grāmatu ieteicējs. 62.epizode. Šodien Burtu Princese un 3D Voldis gatavosies pārgājienam, lasot Klaudijas Tollas un Ilkas Sokolovski noderīgo padomu grāmatu "Dosimies dabā", bet Plankumainais Zirneklis Zenē (TheNee) viņiem traucēs, spēlējoties ar dzejoļiem no Ulda Ausekļa grāmatiņas "Ko dara Runcis Francis". Burtu Burvis ieteiks bērniem īsto grāmatu un pieburs lasītprieku! Dosimies dabā PRINCESE:                Dosimies dabā + ceļvedis pa Latvijas dabas takām!                                     Grāmata izdota sadarbībā ar Latvijas dabas muzeju un Māmiņu klubu. Tūlīt aiz durvīm, laukā – dabā – tevi gaida daudz aizraujošu atklājumu. Tev tikai jāsagatavojas ceļam! Katrā ekspedīcijā daudz kas atkarīgs no iepriekšējās sagatavošanās un pareiza aprīkojuma. Kalnos valda citi likumi, nekā purvā. Pilsētā tev kompasu nevajadzēs, bet ko iesākt nepazīstama meža vidū? Nākamajās lappusēs tu uzzināsi, kas tev šādos gadījumos vienmēr jāņem līdzi, kā orientēties dabā un kā šajā ziņā var palīdzēt laika zīmes. Jāatceras, ka vienmēr var notikt arī kaut kas neparedzēts. Tādēļ būtu labi, ja tev būtu līdzi pirmās palīdzības aptieciņa. Vai esi gatavs? Tad sāksim!”   Ko dara Runcis Francis ZIRNEKLIS:               runcis Francis ķircina Daugavu                                     tāpat kā upes viļņi                                     viņš izstaipās gari,                                     tāpat kā upes viļņi                                     viņš kūkumus met, tāpat kā upes viļņi lec mākoņu astītes ķert –   runcis Francis ķircina Daugavu, bet viņai ir mīļa un laba sirds – tik brīžam pa šķendīgam šļakstam                                     tā nebēdnim ūsgalos sviež…                                       Auu, Burtu Princese, nešļakstinies!   PRINCESE:                Kur tu ņēmi šo dzejoli, Zenē? ZIRNEKLIS:                 Grāmatplauktā. PRINCESE:                Kam tas pieder? ZIRNEKLIS:                 Dzejniekam Uldim Auseklim. VOLDIS:                      Kāpēc tu maisies pa vidu mūsu ceļojumam ar Ulda Ausekļa dzejoli? ZIRNEKLIS:                 Tāpēc, ka es arī gribu piedalīties! VOLDIS:                      Tu tak negribēji nekur doties, Zirnekli! ZIRNEKLIS:                 Negribu nekur doties, bet gribu piedalīties, tepat uz vietas atrodoties! VOLDIS:                      Tas arī ir Ulda Ausekļa dzejolis? ZIRNEKLIS:                 Nē, mans. Nupat izdomāju!  

Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 17/19
The role of Fused in Sarcoma (FUS) in the alternative splicing of TAU

Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 17/19

Play Episode Listen Later Sep 16, 2014


Neurodegenerative disease patients suffer from cognitive decline and/or motor dysfunctions, depending on the different regions affected by the neuron loss. With aging being the major risk factor and a society with increased life expectancy, there is an urgent need to develop new effective treatments to alleviate the situation faced by patients, their families and society. Although neurodegenerative diseases including Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD) lead to different clinical symptoms, they share common pathomechanisms, such as protein aggregation and altered RNA metabolism. A subset of ALS and FTD cases, for instance, is pathologically characterized by neuronal cytoplasmic inclusions containing aggregated Fused in Sarcoma (FUS) protein. There is also a genetic link, since FUS mutations cause ALS with FUS pathology. FUS is a DNA/RNA-binding protein known to regulate different steps of RNA metabolism, however, its exact function and target genes in neurons were unknown. In this study, I evaluated the neuronal role of FUS in alternative splicing using a candidate approach focusing on the microtubule-associated protein TAU. TAU is one of the most widely studied proteins in neurodegeneration research due to its aggregation in different tauopathies, most notably AD. Mutations in the TAU gene MAPT, that affect alternative splicing of exon 10, are known to cause another subtype of FTD. Here, I demonstrate that FUS depleted rat neurons, although having normal viability, show aberrant alternative splicing of TAU, with increased inclusion of exon 3 and exon 10, resulting in higher expression of the 2N and 4R TAU isoforms. Importantly, reintroduction of human FUS rescues aberrant splicing of TAU in FUS depleted neurons. Accordingly, overexpression of FUS decreases expression of 2N and 4R TAU isoforms. In mouse brain lysates, I detected direct FUS binding to TAU pre-mRNA, with strong binding around the regulated exon 10, often at AUU-rich RNA stretches. Since TAU splicing is regulated differently in humans and rodents, I also confirmed the role of human FUS in TAU exon 10 splicing using a TAU minigene and a human neuronal cell line. In addition, I analyzed the morphology and development of axons to evaluate the functional consequences of FUS depletion in neurons. Although FUS depleted neurons develop neurites normally, their axons are significantly shorter than in the control cells. Similar to observations in TAU/MAP1B knockout neurons, axons of FUS depleted neurons develop significantly larger growth cones with abnormal cytoskeletal organization. The development of growth cones in vivo is an essential step in axonal maintenance and repair. Altogether, this study identified TAU as the first physiological splice target of FUS in neurons. The newly discovered role of FUS in regulating the axonal cytoskeleton indicates that aberrant axonal function could contribute to the neuron loss seen in ALS/FTD cases with FUS aggregates.

AU Underground Podcast
AU Underground 020 YokoO

AU Underground Podcast

Play Episode Listen Later Mar 24, 2014 59:36


Sydney based producer/DJ YokoO is my latest guest on AU Underground. Sticking to the AUU brief YokoO has included some productions of his own especially for the podcast. Mixed by: YokoO | https://soundcloud.com/yokoo Presented by: Dylan Griffin | https://soundcloud.com/dylangriffin Post Production by: Adam Barclay Follow YokoO on FB: https://www.facebook.com/yokoomusic Tracklist here: http://www.auunderground.com/podcast/020-yokoo/

fb mixed sticking yokoo auu dylan griffin
Open Day Information Sessions
Your Life On Campus

Open Day Information Sessions

Play Episode Listen Later Sep 19, 2010 0:01


This talk outlines all the non-academic services and activities provided by the AUU that assists you in being part of a vibrant campus culture and gives meaning to your university experience.