Podcasts about Bax

Bax and Nagle 09-11-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 09-10-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 09-09-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 09-08-25 by Rock 102 Morning Show Podcasts

Invasion of the Punk Rockers, Who Drink Blood!: An Ashwood Story (Ashwood Stories) Invasion of the Punk Rockers, Who Drink Blood!A Vampire Horror-Punk Thriller for Rebels, Outcasts, and Anyone Who's Ever Slammed in a Basement Mosh Pit.Bax Laywright and his punk band, Ashwood Commons, are used to being outsiders in the buttoned-up Bible Belt town of Ashwood, Kentucky. They've got fire in their guitars, rebellion in their lyrics, and no patience for small-town conformity. But when a mysterious music collective invites them to play a warehouse show in Louisville, it's the break they've been dying for—until the night turns into a blood-soaked nightmare.The venue? An abandoned slaughterhouse called The Abattoir.The headliner? A gothic band called Crimson Thirst.The fans? Not all of them are human.What starts as a killer show quickly spirals into a trap laid by actual vampires using the underground punk scene to hunt, hypnotize, and harvest the young and rebellious. Bax and his band barely escape with their lives—but the real horror begins when the vampires follow them home.Now, Ashwood Commons isn't just trying to make it out of their dead-end town—they're trying to save it.Armed with guitars, guts, and DIY determination, these teens must rally their scene, outsmart an ancient predator, and fight back before their hometown becomes the next stop on Crimson Thirst's never-ending tour of terror.If The Lost Boys formed a band with Buffy, played a show in Jennifer's Body, and were managed by the ghost of Sid Vicious, you'd get Invasion of the Punk Rockers, Who Drink Blood!—a fierce, funny, and terrifying novel that fuses vampire horror with the raw heart of punk rock.Perfect for fans of:

Bax and Nagle 09-05-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 09-03-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 09-04-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 09-02-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 08-29-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 08-28-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 08-27-25 by Rock 102 Morning Show Podcasts

Annemieke Bosman in gesprek met schrijfster Christine Bax. Deze week verschijnt De nieuwe weg, Bax's zintuiglijke debuutroman. Een verhaal met Twin Peaks-achtige sfeer en magisch realistische elementen, als het Macondo van Gabriel García Márquez in Friesland. Bax vertelt over de verbindingen tussen mensen, generaties, tussen het dorp en de wereld, en over de wens om te ontsnappen aan tijd en realiteit.  De nieuwe weg is een verhaal over een periode die tegelijkertijd lang vervlogen en heel dichtbij is. Het vertelt over de onoverbrugbare kloof tussen generaties en de diepmenselijke wens te ontsnappen aan tijd en realiteit – over een weg, via een kleurentelevisie of door een slok zelfgestookte alcohol.

Bax and Nagle 08-26-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 08-25-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 08-14-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 08-13-25 by Rock 102 Morning Show Podcasts

Hacer click aquí para enviar sus comentarios a este cuento.Juan David Betancur Fernandezelnarradororal@gmail.comHabía una vez en un pueblo del centro mismo del pais una tradición que después de muchas generaciones aún se conservaba en aquella región dedicada exclusivamente a la agricultura. Era la  mañana del 27 de junio  y esta amaneció clara y soleada con el calor lozano de un día de pleno estío; las plantas mostraban profusión de flores y la hierba tenía un verdor intenso. La gente del pueblo empezó a congregarse en la plaza, entre la oficina de correos y el banco, alrededor de las diez; en algunos pueblos había tanta gente que la lotería duraba dos días y tenía que iniciarse el día 26, pero en aquel pueblecito, donde apenas había trescientas personas, todo el asunto ocupaba apenas un par de horas, de modo que podía iniciarse a las diez de la mañana y dar tiempo todavía a que los vecinos volvieran a sus casas a comer.Los niños fueron los primeros en acercarse, por supuesto. La escuela acababa de cerrar para las vacaciones de verano y la sensación de libertad producía inquietud en la mayoría de los pequeños; tendían a formar grupos pacíficos durante un rato antes de romper a jugar con su habitual bullicio, y sus conversaciones seguían girando en torno a la clase y los profesores, los libros y las reprimendas. Bobby Martin ya se había llenado los bolsillos de piedras y los demás chicos no tardaron en seguir su ejemplo, seleccionando las piedras más lisas y redondeadas; Bobby, Harry Jones y Dickie Delacroix acumularon finalmente un gran montón de piedras en un rincón de la plaza y lo protegieron de las incursiones de los otros chicos. Las niñas se quedaron aparte, charlando entre ellas y volviendo la cabeza hacia los chicos, mientras los niños más pequeños jugaban con la tierra o se agarraban de la mano de sus hermanos o hermanas mayores.Pronto empezaron a reunirse los hombres, que se dedicaron a hablar de sembrados y lluvias, de tractores e impuestos, mientras vigilaban a sus hijos. Formaron un grupo, lejos del montón de piedras de la esquina, y se contaron chistes sin alzar la voz, provocando sonrisas más que carcajadas. Las mujeres, con descoloridos vestidos de andar por casa y suéteres finos, llegaron poco después de sus hombres. Se saludaron entre ellas e intercambiaron apresurados chismes mientras acudían a reunirse con sus maridos. Pronto, las mujeres, ya al lado de sus maridos, empezaron a llamar a sus hijos y los pequeños acudieron a regañadientes, después de la cuarta o la quinta llamada. Bobby Martin esquivó, agachándose, la mano de su madre cuando pretendía agarrarlo y volvió corriendo, entre risas, hasta el montón de piedras. Su padre lo llamó entonces con voz severa y Bobby regresó enseguida, ocupando su lugar entre su padre y su hermano mayor. La lotería -igual que los bailes en la plaza, el club juvenil y el programa de la fiesta de Halloween- era dirigida por el señor Summers, que tenía tiempo y energía para dedicarse a las actividades cívicas.El señor Summers era un hombre jovial, de cara redonda, que llevaba el negocio del carbón, y la gente se compadecía de él porque no había tenido hijos y su mujer era una gruñona. Cuando llegó a la plaza portando la caja negra de madera, se levantó un murmullo entre los vecinos y el señor Summers dijo: «Hoy llego un poco tarde, amigos». El administrador de correos, el señor Graves, venía tras él cargando con un taburete de tres patas, que colocó en el centro de la plaza y sobre el cual instaló la caja negra el señor Summers. Los vecinos se mantuvieron a distancia, dejando un espacio entre ellos y el taburete, y cuando el señor Summers preguntó: «¿Alguno de ustedes quiere echarme una mano?», se produjo un instante de vacilación hasta que dos de los hombres, el señor Martin y su hijo mayor, Bax

Bax and Nagle 08-12-25 by Rock 102 Morning Show Podcasts

BUFFALO, NY - August 13, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on July 29, 2025, titled “PCAIs stimulate MAPK, PI3K/AKT pathways and ROS-Mediated apoptosis in aromatase inhibitor-resistant breast cancer cells while disrupting actin filaments and focal adhesion.” In this study, led by first author Jassy Mary S. Lazarte and corresponding author Nazarius S. Lamango from Florida A&M University College of Pharmacy and Pharmaceutical Sciences, researchers investigated a new class of compounds called polyisoprenylated cysteinyl amide inhibitors (PCAIs) as a potential treatment for aromatase inhibitor (AI) therapy resistant breast cancer. Aromatase inhibitors are a common treatment for estrogen receptor-positive (ER+) breast cancer, but many patients eventually develop resistance, leaving fewer therapeutic options. The study focused on a PCAI compound called NSL-YHJ-2-27, which was tested in long-term letrozole-treated breast cancer cells (LTLT-Ca), an experimental model of AI therapy resistance. NSL-YHJ-2-27 activated two major signaling pathways, MAPK and PI3K/AKT. Although these pathways typically support cancer cell survival, their overstimulation by PCAIs led to increased oxidative stress, damaging the cells and inducing cell death by apoptosis. The compound also reduced levels of RAC1 and CDC42, proteins involved in maintaining cell shape and movement. These alterations resulted in cytoskeletal disruption and reduced structural integrity, making the cancer cells more vulnerable and less capable of spreading. Importantly, the effects of NSL-YHJ-2-27 persisted after the compound was removed, suggesting long-term control over AI resistant cancer cells may be possible. “PCAIs inhibited cell proliferation and colony formation by 95% and 74%, respectively, increased active caspase 7 and BAX 1.5-fold and 56%, respectively. NSL-YHJ-2-27 (10 μM) induced LTLT-Ca spheroid degeneration by 61%.” As a new class of targeted molecules, PCAIs represent an innovative approach distinct from traditional endocrine therapies. Their ability to affect multiple cellular mechanisms simultaneously makes them promising candidates for future drug development. Overall, this study presents a promising new approach for treating AI therapy-resistant breast cancer. By targeting cellular pathways that support survival and mobility, PCAIs like NSL-YHJ-2-27 could provide a novel strategy to manage advanced or resistant forms of the disease. Further research, including in vivo studies and clinical trials, will be essential to confirm these findings and evaluate their therapeutic potential. DOI - https://doi.org/10.18632/oncotarget.28759 Correspondence to - Nazarius S. Lamango - nazarius.lamango@famu.edu Video short - https://www.youtube.com/watch?v=8xQEilloO9Q Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28759 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, PCAIs, ROS, MAPK, PI3K/AKT, LTLT-Ca cells To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Bax and Nagle 08-11-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 08-07-25 by Rock 102 Morning Show Podcasts

Bax & Nagle 8-6-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 08-05-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-31-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 08-04-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-30-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-29-05 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-28-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-23-25 by Rock 102 Morning Show Podcasts

Bax and Nagles 07-21-25 by Rock 102 Morning Show Podcasts

Bax and Nagles 07-22-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-17-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-16-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-15-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-14-25 by Rock 102 Morning Show Podcasts

What's up, dudes? It's the Hallmark Ornament Premiere, so I've got the Anthony Caruso from ‘Tis the Podcast and Vinnie Brezinsky from Huey and Bax here to talk the 1989 Hallmark Dreambook—all 32 pages of it! That's right! We get into baubles and finials and cameos! Oh my! We talk our personal collections and which ones from 1989 we own! Spoilers: I have the entire Norman Rockwell cameo set from 80-89! Or do I? Guess you'll have to listen to find out! Peanuts, Paddington, and Rodney Reindeer ornaments make appearances, too! And have you joined the Hallmark Keepsake Ornament Collector's Club yet? Have you decorated your wreaths and garlands with keepsake ornaments? Do you even own a pair of white satin gloves? So bust out your tree and ornaments, put on the Time Life Treasury of Christmas, and travel back to 1989 with this episode!‘Tis the PodcastFB: @tisthepodTwitter: @tisthepodIG: @tisthepodcastGive us a buzz! Send a text, dudes!Check us out on Facebook, Twitter, Instagram, Totally Rad Christmas Mall & Arcade, Teepublic.com, or TotallyRadChristmas.com! Later, dudes!

Bax and Nagle 07-02-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 07-01-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 06-30-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 06-27-25 by Rock 102 Morning Show Podcasts

Bax to the Future - Bax, Spaniard, and Nuno talk about ex's coming back into the picture, grapes, and dirty pastors.  Come out to the Coach House on July 18th and watch Shadow and the Thrill. Hang out with the Hooligans from TheLife.  See y'all there.  www.TheLifePodcast.net TheHooliganCorp@gmail.com

Bax and Nagle 06-26-25 by Rock 102 Morning Show Podcasts

Bax and NAGLE 06-25-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 06-23-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 06-24-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 06-20-25 by Rock 102 Morning Show Podcasts

Rocket Man- Bax, Spaniard, Nuno, and Scoops discuss the past week's activities.  Bax launched into outer space and took a nap on the rings of Saturn.  Yup! Way out there.  www.TheLifePodcast.net TheHooliganCorp@gmail.com  

Bax and Nagle 06-19-25 by Rock 102 Morning Show Podcasts

Bax and Nagle 06-18-25 by Rock 102 Morning Show Podcasts