Podcast appearances and mentions of Paul E Sax

In this episode, Princy N. Kumar, MD, and Paul E. Sax, MD, discuss new COVID-19 data from IDWeek 2022, including:COVID-19 vaccines, including omicron BA.1 bivalent boosterRisk factors for breakthrough COVID-19 infectionsCOVID-19 diagnostics, including digital droplet PCRCOVID-19 therapeutics, including:Nirmatrelvir plus ritonavirTixagevimab plus cilgavimabBaricitinibTocilizumabInhaled interferon β-1aCOVID-19 therapeutics and outcomes in patients with immunocompromiseLong COVIDPresenters:Princy N. Kumar, MD, FIDSA, MACPProfessor of Medicine and MicrobiologyChief, Division of Infectious Diseases and Travel MedicineSenior Associate Dean of StudentsGeorgetown University School of MedicineWashington, DCPaul E. Sax, MDClinical DirectorHIV Program and Division of Infectious DiseasesBrigham and Women's HospitalProfessor of MedicineHarvard Medical SchoolBoston, MassachusettsFollow along with the downloadable slideset at:http://bit.ly/3gkJI67Link to full program:http://bit.ly/3TSVthM

In this episode, Paul E. Sax, MD, discusses the latest recommendations and options for HIV pre-exposure prophylaxis (PrEP), including:CDC PrEP guideline 2021 updates for oral PrEPThe ANRS IPERGAY study: on-demand oral emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) PrEP in men who have sex with men who are at high risk for HIV infectionA review of the HPTN 083 and 084 studies: efficacy and safety of long-acting (LA) injectable cabotegravir (CAB) vs daily oral FTC/TDF for PrEP1-year follow-up after unblinding for HPTN 083 and 084LA CAB for PrEP: monitoring and safetyStopping LA CAB for PrEPPresenter: Paul E. Sax, MDClinical DirectorHIV Program and Division of Infectious DiseasesBrigham and Women's HospitalProfessor of MedicineHarvard Medical SchoolBoston, MassachusettsLink to full program:https://bit.ly/3VIsDTgFollow along with the slides at:https://bit.ly/3Gh9AKG

In this episode, Paul E. Sax, MD, discusses long-acting (LA) injectables for HIV treatment, including: Guidance on the use of LA cabotegravir (CAB) + rilpivirine (RPV)Risk factors for virologic failure of LA CAB + RPVThe ATLAS-2M studyCombined clinical trials of LA CAB + RPVPractical considerations for LA CAB + RPVImplementation of LA CAB + RPV Switching to LA CAB + RPV without an oral lead-in, including a discussion of the FLAIR extension studySupporting candidates for LA antiretroviral therapy (ART)Discussion of an implementation study of LA CAB + RPV in patients with challenges to oral ART adherence in San FranciscoFuture LA ART The investigational LA HIV capsid inhibitor lenacapavir (LEN)LEN resistance from the CAPELLA and CALIBRATE studiesLEN injection-site reactions in the CAPELLA and CALIBRATE studiesPresenter: Paul E. Sax, MDClinical DirectorHIV Program and Division of Infectious DiseasesBrigham and Women's HospitalProfessor of MedicineHarvard Medical SchoolBoston, MassachusettsLink to full program:https://bit.ly/3VIsDTgFollow along with the slides at:http://bit.ly/3Gh9AKG

In this episode, Joel M. Gelfand, MD, MSCE, and Leonard H. Calabrese, DO, are joined by Paul E. Sax, MD, as they discuss advances in the outpatient management of COVID-19 and emerging information about the omicron variant. Welcome from Joel Gelfand, MD, MSCE :10 About Calabrese, Gelfand and Sax :25 A quick update since the last webinar :51 Sax's thoughts on the effectiveness of monoclonal antibodies 1:46 What are the situations where we should be thinking about postexposure prophylaxis with these agents? 7:06 When you start using pre-exposure prophylaxis therapy, how would you counsel the patients receiving it? 12:56 How does Merck's molnupiravir work? 17:22 Sax's thoughts on Pfizer's paxlovid 22:23 What's your perspective on fluvoxamine? Does it work? 25:26 Paul, what have you learned so far about the omicron variant? 30:15 How much more contagious is this than Delta and what would you compare it to? 31:09 Questions from the audience 35:27 Tweet your questions @DrJoelGelfand, @LCalabreseDO and @PaulSaxMD. 38:35 Leonard H. Calabrese, DO, is chief medical editor of Healio Rheumatology, professor of medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, and RJ Fasenmyer Chair of Clinical Immunology at the Cleveland Clinic. Joel M. Gelfand, MD, MSCE, is chief medical editor of Healio Psoriatic Disease and professor of dermatology and epidemiology at the Perelman School of Medicine at the University of Pennsylvania. He is also vice chair of clinical research, medical director at the Dermatology Clinical Studies Unit, and director of the Psoriasis and Phototherapy Treatment Center at Penn Medicine. Paul E. Sax, MD, is clinical director of the Infectious Disease Clinic and professor of medicine at Harvard Medical School. We'd love to hear from you! Send your comments/questions to Drs. Gelfand, Calabrese and Sax at covid19podcast@healio.com. Be sure to check Healio.com/coronavirus for daily updates on the pandemic and follow us on Twitter @InfectDisNews, @GoHealio, @DrJoelGelfand, @LCalabreseDO and @PaulSaxMD. Disclosures: Calabrese reports consulting for AstraZeneca, GSK and Regeneron. Gelfand and Sax report no relevant financial disclosures. 

In this podcast episode, Paul E. Sax, MD, and Renslow Sherer, MD, discuss the clinical significance of new data on the prevention and treatment of COVID-19, including:COVID-19 in immunocompromised hostsPrime-Boost Strategy for COVID-19 vaccinationCOVID-19 surge effectsMonoclonal antibody therapy for prevention and treatmentRemdesivir updateRepurposed drug, fluvoxamineWhat does the future of the pandemic look like?Presenters:Paul E. Sax, MDClinical DirectorHIV Program and Division of Infectious DiseasesBrigham and Women's HospitalProfessor of MedicineHarvard Medical SchoolBoston, MassachusettsRenslow Sherer, MDDirectorInternational HIV Training CenterProfessor of MedicineSection of Infectious Diseases and Global HealthDepartment of MedicineUniversity of ChicagoChicago, IllinoisLink to full program, including downloadable slidesets:https://bit.ly/3zVTwYW

In this episode, Paul E. Sax, MD, discusses emerging drug therapies and treatment options for patients with HIV, including rapid initiation of ART, long-acting ART, and 2-drug ART regimens. The overview will include analyses from:The RAPID ART program in San Francisco, where same-day initiation of ART led to faster HIV-1 RNA suppression that was maintained at greater than 92% during a 3-year periodThe DIAMOND study analyzing virologic efficacy and safety at 48 weeks after initiating DRV/COBI/FTC/TAF within 24 hours of HIV infection diagnosisA rapid ART start program in young PWH in New Orleans that demonstrated achievement of viral suppression in fewer than 30 days and no discontinuations due to adverse eventsThe ATLAS (including ATLAS-2M) and FLAIR studies that demonstrated efficacy and safety of long-acting injectable CAB plus RPVSWORD-1 and SWORD-2 that demonstrated switching to a 2-drug regimen of DTG plus RPV in virologically suppressed adults was safe and effectiveGEMINI-1 and GEMINI-2 that demonstrated noninferiority of DTG plus 3TC compared with DTG plus FTC/TDFTANGO that demonstrated safety and efficacy of switching to DTG/3TC in virologically suppressed adults receiving a TAF-based regimenIn addition, Dr. Sax reviews current recommendations by the DHHS, WHO, and IAS-USA regarding these emerging therapies and treatment paradigms.  Presenter:Paul E. Sax, MDClinical DirectorHIV Program and Division of Infectious DiseasesBrigham and Women's HospitalProfessor of MedicineHarvard Medical SchoolBoston, MassachusettsFollow along with the slides at:https://bit.ly/3zdPwm2 Content based on an online CME program supported by an educational grant from ViiV Healthcare.Link to full program:https://bit.ly/3ux6FF8

Credits: 0.50 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-covid-outpatient   Overview: So much has changed concerning COVID-19 management, but few interventions are clearly beneficial in the outpatient management of patients.  This podcast will try to answer some of the common questions community based providers have about handling their patients’ illness. Episode reference links:  Vitamin D for COVID-19 (VIVID) study STOP COVID Trial Rise Above COVID   Guest: Paul E. Sax, MD   Music Credit: Richard Onorato

Credits: 0.50 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-covid-outpatient   Overview: So much has changed concerning COVID-19 management, but few interventions are clearly beneficial in the outpatient management of patients.  This podcast will try to answer some of the common questions community based providers have about handling their patients’ illness. Episode reference links:  Vitamin D for COVID-19 (VIVID) study STOP COVID Trial Rise Above COVID   Guest: Paul E. Sax, MD   Music Credit: Richard Onorato

In this episode, Part 8 of an ongoing series, Paul E. Sax, MD, provides a brief update on current treatment options for COVID-19. After the update, Dr. Sax answers clinician questions on various aspects of COVID-19.Presenter:Paul E. Sax, MDClinical Director HIV Program and Division of Infectious DiseasesBrigham and Women's HospitalProfessor of MedicineHarvard Medical SchoolBoston, MassachusettsContent based on an online CME program supported by an independent educational grant from Gilead Sciences.Link to full program:https://bit.ly/3eDoJF0

Go online to PeerView.com/QDX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in infectious diseases discusses guidance for healthcare professionals involved in the treatment of patients with COVID-19. Upon completion of this activity, participants will be able to: Describe the epidemiology and virology of coronavirus disease 2019 (COVID-19), Evaluate patients with suspected COVID-19 infection in accordance with current guidance from the Centers for Disease Control and Prevention (CDC), recognizing that recommendations may be adapted by state and local health departments to respond to rapidly changing local circumstances, Assess the efficacy, safety, and appropriate clinical utilization of current and emerging COVID-19 management and prevention strategies, Employ evidence-based protocols to provide appropriate care for patients with suspected or confirmed COVID-19.

Go online to PeerView.com/QDX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in infectious diseases discusses guidance for healthcare professionals involved in the treatment of patients with COVID-19. Upon completion of this activity, participants will be able to: Describe the epidemiology and virology of coronavirus disease 2019 (COVID-19), Evaluate patients with suspected COVID-19 infection in accordance with current guidance from the Centers for Disease Control and Prevention (CDC), recognizing that recommendations may be adapted by state and local health departments to respond to rapidly changing local circumstances, Assess the efficacy, safety, and appropriate clinical utilization of current and emerging COVID-19 management and prevention strategies, Employ evidence-based protocols to provide appropriate care for patients with suspected or confirmed COVID-19.

Go online to PeerView.com/QDX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in infectious diseases discusses guidance for healthcare professionals involved in the treatment of patients with COVID-19. Upon completion of this activity, participants will be able to: Describe the epidemiology and virology of coronavirus disease 2019 (COVID-19), Evaluate patients with suspected COVID-19 infection in accordance with current guidance from the Centers for Disease Control and Prevention (CDC), recognizing that recommendations may be adapted by state and local health departments to respond to rapidly changing local circumstances, Assess the efficacy, safety, and appropriate clinical utilization of current and emerging COVID-19 management and prevention strategies, Employ evidence-based protocols to provide appropriate care for patients with suspected or confirmed COVID-19.

Go online to PeerView.com/QDX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in infectious diseases discusses guidance for healthcare professionals involved in the treatment of patients with COVID-19. Upon completion of this activity, participants will be able to: Describe the epidemiology and virology of coronavirus disease 2019 (COVID-19), Evaluate patients with suspected COVID-19 infection in accordance with current guidance from the Centers for Disease Control and Prevention (CDC), recognizing that recommendations may be adapted by state and local health departments to respond to rapidly changing local circumstances, Assess the efficacy, safety, and appropriate clinical utilization of current and emerging COVID-19 management and prevention strategies, Employ evidence-based protocols to provide appropriate care for patients with suspected or confirmed COVID-19.

Go online to PeerView.com/QDX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in infectious diseases discusses guidance for healthcare professionals involved in the treatment of patients with COVID-19. Upon completion of this activity, participants will be able to: Describe the epidemiology and virology of coronavirus disease 2019 (COVID-19), Evaluate patients with suspected COVID-19 infection in accordance with current guidance from the Centers for Disease Control and Prevention (CDC), recognizing that recommendations may be adapted by state and local health departments to respond to rapidly changing local circumstances, Assess the efficacy, safety, and appropriate clinical utilization of current and emerging COVID-19 management and prevention strategies, Employ evidence-based protocols to provide appropriate care for patients with suspected or confirmed COVID-19.

Go online to PeerView.com/QDX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in infectious diseases discusses guidance for healthcare professionals involved in the treatment of patients with COVID-19. Upon completion of this activity, participants will be able to: Describe the epidemiology and virology of coronavirus disease 2019 (COVID-19), Evaluate patients with suspected COVID-19 infection in accordance with current guidance from the Centers for Disease Control and Prevention (CDC), recognizing that recommendations may be adapted by state and local health departments to respond to rapidly changing local circumstances, Assess the efficacy, safety, and appropriate clinical utilization of current and emerging COVID-19 management and prevention strategies, Employ evidence-based protocols to provide appropriate care for patients with suspected or confirmed COVID-19.

Go online to PeerView.com/QDX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in infectious diseases discusses guidance for healthcare professionals involved in the treatment of patients with COVID-19. Upon completion of this activity, participants will be able to: Describe the epidemiology and virology of coronavirus disease 2019 (COVID-19), Evaluate patients with suspected COVID-19 infection in accordance with current guidance from the Centers for Disease Control and Prevention (CDC), recognizing that recommendations may be adapted by state and local health departments to respond to rapidly changing local circumstances, Assess the efficacy, safety, and appropriate clinical utilization of current and emerging COVID-19 management and prevention strategies, Employ evidence-based protocols to provide appropriate care for patients with suspected or confirmed COVID-19.

Go online to PeerView.com/QDX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in infectious diseases discusses guidance for healthcare professionals involved in the treatment of patients with COVID-19. Upon completion of this activity, participants will be able to: Describe the epidemiology and virology of coronavirus disease 2019 (COVID-19), Evaluate patients with suspected COVID-19 infection in accordance with current guidance from the Centers for Disease Control and Prevention (CDC), recognizing that recommendations may be adapted by state and local health departments to respond to rapidly changing local circumstances, Assess the efficacy, safety, and appropriate clinical utilization of current and emerging COVID-19 management and prevention strategies, Employ evidence-based protocols to provide appropriate care for patients with suspected or confirmed COVID-19.

Practical tips and discussion of what we do and don’t know about COVID-19 transmission, testing, NSAIDs, ACE inhibitors, quarantine, treatment, personal protective equipment (PPE) and more with Paul Sax MD, @paulsaxMD (Brigham and Women’s Hospital/Harvard Medical School). This episode is sure to go viral! Show Notes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com    Credits Written and Produced by: Sarah Phoebe Roberts MPH; Chris Chiu MD; Beth Garbitelli; Hannah Abrams; Rahul Ganatra MD, MPH; Matthew Watto MD, FACP Cover Art and Infographic by: Beth Garbitelli Hosts: Rahul Ganatra MD, MPH; Matthew Watto MD, FACP; Paul Williams MD, FACP    Editor: Matthew Watto MD (written materials); Clair Morgan of nodderly.com Guest: Paul Sax MD   Sponsor Primary Care Internal Medicine of Ithaca Join a well established practice in beautiful upstate New York near the finger lakes and wine country! You'll have flexible hours and the ability to take the time you need with patients! Contact Dr. Ann Costello arcostello@gmail.com to find out more about this incredible opportunity to join the team at Primary Care Internal Medicine of Ithaca https://www.primarycareinternalmedicineofithaca.com/.   Time Stamps   00:00 Sponsor- Primary Care Internal Medicine of Ithaca https://www.primarycareinternalmedicineofithaca.com/ 00:20 Intro, guest bio, guest one-liner 04:12 SARS-CoV-2/COVID-19 vs. SARS, MERS, and influenza  07:00 Rahul highlights areas of caution interpreting COVID cases studies  12:35 Sponsor- Primary Care Internal Medicine of Ithaca https://www.primarycareinternalmedicineofithaca.com/ 13:20 Case of cold symptoms; Wearing masks in public; Advice on self quarantine with mild symptoms 18:05 Patient with mild symptoms and COVID exposure; Duration of quarantine and PCR positivity 21:15 Who merits testing for COVID-19 23:19 Case of confirmed COVID with mild symptoms; Instructions to patient and family about quarantine 25:50 COVID-19 testing characteristics (sensitivity, false negatives); Does co-infection occur?; Advice on when to send patient to a hospital  30:10 ACEIs, ARBs, NSAIDS; Is reinfection possible? 32:20 Pharmacotherapy: Hydroxychloroquine, Remdesivir, Tocilizumab; Definition of the “high risk” patient; COVID-19 vaccine 36:50 Case of healthcare worker (HCW) with COVID exposure; How long can COVID live on surfaces?  40:20 Do exposed HCWs without symptoms require quarantine? 41:30 Personal Protective equipment (PPE) 45:00 COVID-19 in pregnancy 47:30 COVID-19 and vulnerable patient populations (patients who are immigrants, homeless, incarcerated, etc.)  50:45 Where should you get your COVID-19 information? 52:30 Closing remarks and outro   Goals Listeners will review the current research on COVID-19 including transmission, protection strategies, testing, symptoms, and basics of management.   Learning objectives After listening to this episode listeners will know… The basics of COVID-19 including epidemiology, prevention, transmission, and treatment Where to find reliable data sources and how to interpret new studies with caution  The importance of PPE and limiting disease exposure  What drug regimens are recommended and what experimental treatments are available The role of virtual visits, telemedicine and other non-traditional methods to reduce patient contact Impact of COVID-19 on at-risk populations    Disclosures Paul E. Sax, MD, has disclosed the following relevant financial relationships:  Served as a director, officer, partner, employee, advisor, consultant, or trustee for: Bristol-Myers Squibb Company; Gilead Sciences, Inc.; GlaxoSmithKline; Janssen; Merck. Received research grant from: Bristol-Myers Squibb Company; Gilead Sciences, Inc.; GlaxoSmithKline; Merck. The Curbsiders report no relevant financial disclosures.    Citation Sax P, Roberts SP, Chiu CJ, Garbitelli B, Abrams H, Williams PN, Watto MF. “#200 COVID-19 with Paul Sax MD”. The Curbsiders Internal Medicine Podcast. https://thecurbsiders.com/episode-list. March 22, 2020.

Credits: 0.50 AMA PRA Category 1 Credits™ Claim CME/CE credit: http://www.pri-med.com/online-education/Podcast/south-2020-sax-ask-the-expert  Overview: Get your questions answered by an expert faculty in Infectious Disease. You ask: we listen. You will learn practical solutions to common clinical challenges and tips to apply the latest knowledge in practice. Please note that any data, indications, and guidelines presented in this activity are current as of the recording/release on February 7, 2020, and they are subject to change as new information is published. Guest: Guest: Paul E. Sax, MD

Episode description Emma Levine presents a clinical unknown to Dr. Paul Sax Download CPSolvers App here Dr. Paul Sax Dr. Paul E. Sax is Clinical Director of the Division of Infectious Diseases and the HIV Program at Brigham and Women’s Hospital (BWH), and Professor of Medicine at Harvard Medical School. Dr. Sax received his MD… Read More »Episode 54 – Clinical unknown w/ Dr. Paul Sax – Fever and Headache

Episode description Dan Minter presents a clinical unknown to Dr. Paul Sax Download CPSolvers App here Dr. Paul Sax Dr. Paul E. Sax is Clinical Director of the Division of Infectious Diseases and the HIV Program at Brigham and Women’s Hospital (BWH), and Professor of Medicine at Harvard Medical School. Dr. Sax received his MD… Read More »Episode 53 – Clinical unknown Dr. Paul Sax – Cough & Rash

Lyme disease and tick-borne illness deconstructed by Infectious Diseases expert, Paul E. Sax MD, of episode 78 fame. Oh, Summer Nights. The time for romance between Danny Zuko and good girl Sandy, the time to sit in the backyard around the bonfire, the time for sunset hikes in the woods and mountains…..and don’t forget, it’s also the time for those pesky woodland ticks who’ll go for a ride on you and maybe suck your blood (gross!). Dr. Sax takes us through the essentials of tick-borne illness, with a focus on Lyme Disease: diagnosing it, treating it, identifying possible co-infections, and managing Post-Lyme residual symptoms.   Our (And Dr. Sax’s) Disclaimer about this episode, and the shownotes: Tick-borne illness is a very serious problem in public health in the US, but management is quite a controversial issue. We’ve done our best with this episode to stay as evidence-based as possible. Moreover, given the limited time we have on air, we have tried to focus on what we think is most clinically relevant. Full show notes available at http://thecurbsiders.com/podcast Join our mailing list and receive a PDF copy of our show notes every Monday. Rate us on iTunes, recommend a guest or topic and give feedback at thecurbsiders@gmail.com. Credits: Written by: Shreya P. Trivedi MD, Nora Taranto AB Produced by: Shreya P. Trivedi MD, Nora Taranto AB Editor: Matthew Watto MD Images by:  Hannah R. Abrams Hosts: Shreya P. Trivedi MD, Matthew Watto MD, Paul Williams MD Guest: Paul E. Sax MD Time Stamps 00:00 Intro 02:17 Disclaimer 03:19 Guest bio 05:17 Getting to know Guest 08:33 Favorite hiking experiences 12:20 Disclaimer of Tick-borne illness 12:28 Clinical case of recent hiking in endemic area with a rash 20:59 Lyme testing limitations 27:38 Patient education to doxycycline 30:16 Case of elderly outdoorsy healthy male with flu-like symptoms in the summer 32:39 Differentiating anaplasmosis and babesiosis 33:17 Workup for patient with possible tick co-infections 39:22  Post-lyme disease residual symptoms 48:02  Case of tick attached to patient 56:19  Outro Tags: lyme, disease, anaplasmosis, babesiosis, treatment, prevention, coinfection, doxycycline, paul, sax, infectious, diseases, nejm, harvard, pcr, antibody, tick, borne, illness, chronic, post, syndrome, removal, endemic, anatomical, assistant, care, doctor, education, family, FOAM, FOAMim, FOAMed, health, hospitalist, hospital, internal, internist, meded, medical, medicine, nurse, practitioner, professional, primary, physician, resident, student