Podcasts about hospitalization

Episode 190: Measles BasicsFuture Dr. Kapur explained the basics of measles, including the pathophysiology, diagnosis and management of this disease. Dr. Schlaerth added information about SPPE and told interesting stories of measles. Dr. Arreaza explained some statistics and histed the episode.  Written by Ashna Kapur MS4 Ross University School of Medicine. Comments by Katherine Schlaerth, MD, and Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Introduction.According to the CDC, as of April 24, 2025, a total of 884 confirmed measles cases were reported by 30 states, including California, and notably Texas. This is already three times more cases than 2024. There are 3 confirmed deaths so far in the US. What is measles?Measles is a disease that's been around for centuries, nearly eradicated, yet still lingers in parts of the world due to declining vaccination rates. Let's refresh our knowledge about its epidemiology, clinical features, diagnosis, management, and most importantly — prevention.Definition.Measles, also known as rubeola, is an acute viral respiratory illness caused by the measles virus. It's a single-stranded, negative-sense RNA virus belonging to the Paramyxoviridae family. It's extremely contagious with a transmission rate of up to 90% among non-immune individuals when exposed to an infected person.EpidemiologyBefore the introduction of the measles vaccine in 1963, nearly every child got measles by the time they were 15 years old. With the introduction of vaccination, cases and deaths caused by measles significantly declined. For example, in 2018, over 140,000 deaths were reported in the whole world, mostly among children under the age of 5.Measles is still a common disease in many countries, including in Europe, the Middle East, Asia, and Africa. Measles outbreaks have been reported recently in the UK, Israel, India, Thailand, Vietnam, Japan, Ukraine, the Philippines, and more recently in the US. So, let's take prevention seriously to avoid the spread of this disease here at home and abroad. How do we get measles, Ashna?Mode of Transmission:● Air: Spread primarily through respiratory droplets.● Surfaces: The virus remains viable on surfaces or in the air for up to 2 hours. (so, if a person with measles was in a room and you enter the same room within 2 hours, you may still get measles)● Other people: Patients are contagious from 4 days before until 4 days after the rash appears.PathophysiologyThe measles virus first infects the respiratory epithelium, replicates, and then disseminates to the lymphatic system.It leads to transient but profound immunosuppression, which is why secondary infections are common. It affects the skin, respiratory tract, and sometimes the brain, leading to complications like pneumonia or encephalitis.Clinical PresentationThe classic presentation of measles can be remembered in three C's:● Cough● Coryza (runny nose)● ConjunctivitisCourse of Disease (3 Phases):1. Prodromal Phase (2-4 days)○ High fever (can peak at 104°F or 40°C)○ The 3 C's○ Koplik spots: Small white lesions on the buccal mucosa.2. Exanthem Phase○ Maculopapular rash begins on the face (especially around the hairline), then spreads from head to toe. The rash typically combines into 1 big mass as it spreads, and the fever often persists during the rash.3. Recovery Phase○ Rash fades in the same order it appeared.○ Patients remain at risk for complications during and after rash resolution.Complications:● Pneumonia (most common cause of death in children)● Otitis media (most common overall complication)● Encephalitis (can lead to permanent neurologic sequelae)● Subacute sclerosing panencephalitis (SSPE): A rare, fatal, degenerative CNS disease that can occur years after measles infection.High-risk groups for severe disease include:● Infants and young children● Pregnant women● Immunocompromised individualsDiagnosisClinical diagnosis is sufficient if classic symptoms are present, especially in outbreak settings.Ashna: Laboratory confirmation:● Measles-specific IgM antibodies detected by serology.● RT-PCR from nasopharyngeal, throat, or urine samples.Notify public health authorities immediately upon suspicion or diagnosis of measles to limit spread. ManagementThere is no specific antiviral treatment for measles. Management is supportive:● Hydration (by mouth and only IV in case of severe dehydration)● Antipyretics (e.g., acetaminophen) for fever● Oxygen if hypoxicVitamin A supplementation:● Recommended for all children with acute measles, particularly in areas with high vitamin A deficiency. It has shown to reduce morbidity and mortality.Hospitalization may be necessary for:● Severe respiratory compromise● Dehydration● Neurologic complicationsPrevention: We live in perilous times and vaccination is under scrutiny right now. Before the measles vaccine, about 48,000 people were hospitalized and 400–500 people died in the United States every year. Measles was declared eradicated in the US in 2000, but the vaccination coverage is no longer 95%. How do we prevent measles?Vaccination is the cornerstone of prevention.● MMR vaccine (Measles, Mumps, Rubella):○ First dose at 12-15 months of age.○ Second dose at 4-6 years of age.○ 97% effective after 2 doses.The Advisory Committee on Immunization Practices (ACIP) has noted that febrile seizures typically occur 7 to 12 days after vaccination with MMR, with an estimated incidence of 3.3 to 8.7 per 10,000 doses. The Centers for Disease Control and Prevention (CDC) states that febrile seizures following MMR vaccination are rare and not associated with any long-term effects. The risk of febrile seizures is higher when the MMR vaccine is administered as part of the combined MMRV (measles, mumps, rubella, and varicella) vaccine compared to the MMR vaccine alone.Post-exposure prophylaxis:● MMR vaccine within 72 hours of exposure (if possible).● Immunoglobulin within 6 days for high-risk individuals (e.g., infants, pregnant women, immunocompromised).Herd immunity requires at least 95% vaccination coverage to prevent outbreaks.Key Takeaways● Measles is a highly contagious viral illness that can lead to severe complications.● Diagnosis is often clinical, but lab confirmation helps with public health tracking.● Treatment is mainly supportive, with Vitamin A playing a critical role in reducing complications.● Vaccination remains the most effective tool to eliminate measles worldwide.While measles might seem like a disease of the past, it can make a dangerous comeback without continued vigilance and vaccination efforts.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Centers for Disease Control and Prevention (CDC). Measles (Rubeola), Clinical Overview, July 15, 2024. Accessed on May 1, 2025. https://www.cdc.gov/measles/hcp/clinical-overview/index.html.World Health Organization (WHO). Measles, November 14, 2024. https://www.who.int/news-room/fact-sheets/detail/measlesGans, Hayley and Yvonne A. Maldonado, Measles: Clinical manifestations, diagnosis, treatment, and prevention, UpToDate, January 15, 2025. Accessed on May 1, 2025. https://www.uptodate.com/contents/measles-clinical-manifestations-diagnosis-treatment-and-preventionTheme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

The hardest chapters of your life often become the clearest mirror of your values. When Rabbi Jonathan Cohen woke up one Shabbat (Saturday) morning unable to move, he had no idea he was facing a life-altering medical emergency. What followed - emergency brain surgery, a cancer diagnosis, and a whirlwind of hospital visits - could have broken his spirit. Instead, it clarified his purpose. In this raw and deeply human conversation, Jonathan - affectionately known as "JoCo" - shares how he continues to show up with purpose during hard times, for his family, his community, and himself, even in the midst of fear, fatigue, and the unknown. With humor, wisdom, and an unmistakable warmth, he invites us to rethink what it means to live meaningfully when life turns upside down. This isn't just a story about illness. It's a story about resilience, presence, and the power of showing up with purpose, even when everything else falls away. In this conversation about showing up with purpose during hard times, you'll hear: The Shabbat (Saturday) morning that changed everything for Jonathan How he stayed grounded in his values through a health crisis and what helps him through the hard times What it meant for him to suddenly be a patient What makes a visit meaningful when someone is seriously ill Caring for others and visiting communities affected by October 7, even as he confronts his own health challenges Jonathan's reflections on vulnerability, community, and setting boundaries And many more insights   TIMESTAMPS 00:00 – Introduction to Jonathan Cohen's Journey 01:37 – Life Before the Cancer Diagnosis 07:27 – The Morning Everything Changed 13:59 – Emergency Brain Surgery and Hospitalization 21:03 – Adjusting to Life as a Patient 26:50 – Support from Family and Friends 32:09 – Navigating Visits and Staying Positive 36:12 – What Makes a Visit Truly Meaningful 40:10 – Balancing Illness with Family Life 40:57 – Creative Ways Visitors Made an Impact 42:44 – Community Engagement as a Healing Practice 45:44 – The Therapeutic Power of Getting Outside 47:37 – Supporting Others Through Small Gestures 50:28 – Seeing Life Differently Through Illness 55:42 – Fighting vs. Managing Illness 59:33 – Finding Strength Through Support and Positivity 01:02:44 – Final Reflections and Life Lessons   ABOUT THE GUEST Rabbi Jonathan Cohen (affectionately known as "JoCo") is a dynamic force of inspiration within the Jewish community. He works with Yeshiva University (YU) recruiting gap-year students to continue their education at YU, while also serving with NCSY (a division of the Orthodox Union) to help young couples find their place in Jewish communities across the United States. Beyond his professional roles, Rabbi Cohen is renowned for his exceptionally warm and open home, where he and his family have hosted countless students for Shabbos and Yom Tov meals. Recently diagnosed with cancer, Rabbi Cohen faces this challenge with remarkable resilience and positivity. Despite undergoing intensive treatment, he remains steadfast in his mission to serve others. He continues to travel across Israel, leading impactful trips and providing support to communities affected by the events of October 7th, turning his personal struggle into an opportunity to spread kindness and connection to those in need. QUOTES “Being a hero also means going through challenges and creating opportunities.” - Jonathan Cohen “What I've learned most importantly is that we have to be there more for each other.” - Jonathan Cohen “That first week, there were certain people [who] weren't even thinking about themselves. They were thinking about ‘what can we do to put a smile on your face?'” - Jonathan Cohen “Communication is still a hard thing in the generation that we live.” - Jonathan Cohen ABOUT THE HOST Uri Schneider, M.A. CCC -SLP is co-founder and leader at Schneider Speech; creator and host of Transcending Stuttering; and former faculty at the University of California, Riverside School of Medicine. SEE ALL SHOW NOTES http://www.transcendingx.com/podcast LEARN MORE at http://www.transcendingx.com and http://www.schneiderspeech.com

Send us a textIn this episode of Causes or Cures, Dr. Eeks talks with Dr. Mary Abed Al Ahad about how long-term exposure to air pollution is quietly driving people to the hospital. Drawing from her recent study, Dr. Abed Al Ahad breaks down which specific pollutants were linked to higher hospitalization rates and how those effects vary—some pollutants hit the lungs harder, others may affect the immune system or even mental health. They also explore the science behind why certain pollutants cause different kinds of harm, and wrap up with ideas for how we can clean up the air and protect our health. If you've ever wondered what's really in the air you breathe—and what it's doing to your body—this episode is worth a listen. Dr. Abed Al Ahad is a researcher and associate lecturer in Population and Health Geography at the School of Geography & Sustainable Development, University of St Andrews in Scotland. You can learn more about her research here. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her monthly newsletter here.Support the show

Welcome back to the Contacts Coaching Podcast. Today, we have the honor of speaking with Robert Paylor, an inspirational speaker and author. In this episode, Robert shares his incredible journey of overcoming a traumatic spinal cord injury during a national championship rugby game in 2017. He discusses his initial prognosis, the monumental challenges he faced, and the relentless effort that has brought him to where he is today. Robert also talks about the importance of maintaining a positive mindset, the invaluable support of his family, friends, and the rugby community, and his new book, 'Paralyzed to Powerful,' set to release on May 6th. Don't miss this poignant and uplifting story of resilience and hope.00:00 Introduction and Guest Welcome00:50 Early Life and Athletic Background02:29 Transition to Rugby and High School Achievements04:04 College Rugby and the Life-Changing Injury09:26 Hospitalization and Initial Recovery11:30 Rehabilitation Journey and Return to Berkeley14:42 Support System and Overcoming Challenges17:31 Mindset and Positivity in Recovery21:38 Maintaining Perspective and Empathy24:36 Mental Diet and Surrounding Yourself with Positivity26:53 Navigating Information Overload27:05 Balancing Big Goals with Reality28:05 The Daily Grind of Recovery32:07 Understanding Spinal Cord Injuries38:41 The Power of Relationships in Sports42:47 The Unique Community of Rugby45:45 Finding Purpose Through Adversity49:17 Advice for Athletes and Coaches52:38 Upcoming Book and Final ThoughtsWebsite: https://www.robertpaylor.com/Instagram: https://www.instagram.com/rob.paylor/X: https://x.com/RobertPaylor5Facebook: https://www.facebook.com/robertpaylor5LinkedIn: http://linkedin.com/in/robert-paylorTikTok: https://www.tiktok.com/@rob.paylor

Home is where the heart is — and where most of us would rather…

Home is where the heart is — and where most of us would rather be when we don't feel well. Now, a new study from researchers in England suggests that...

For a lot of us, the answer isn't simple. You can miss your lighter, less-traumatized self and feel proud of who you've become.That's the tension so many of us sit in as medical parents: grieving the carefree, well-rested version of ourselves while also seeing strength, resilience, and depth we didn't know we had.In this episode, I'm joined by Alyssa Nutile to unpack the big, messy feelings that come with identity loss, personality shifts, and how we change when our child's life is on the line, plus the unexpected ways we've grown and adapted.Links:Hear Alyssa's other episodes: 180: Does it get easier?, 179: Exhaustion, 174: Silencing, 171: Financial Strain, 170: Hospitalizations, 140: Alyssa's Story, 125: Travel w/ Disabled KidsFill out our contact form to join upcoming discussion groups!Follow Alyssa at @caffeinated_caregivers!Follow us on Instagram @the_rare_life!Donate to the podcast or Contact me about sponsoring an episode.Follow the Facebook page.Join the Facebook group Parents of Children with Rare Conditions.Access the transcript on the website here.And if you love this podcast, please leave us a rating or review in your favorite podcast app!

What happens when success meets struggle head-on? In this powerful and unfiltered episode of Bro Talk, host Gary Napier sits down with Christopher Scholey, a former London pub owner turned mental health advocate, to uncover the highs and harrowing lows of living with bipolar disorder. Chris opens up about: - His wild ride running the legendary Bedford Pub - The crushing reality of his first manic episode - Hospitalizations, arrests, and facing rock bottom - The healing power of writing and reflection - Rebuilding his life—and redefining success on his own terms This deeply human story is a must-watch for anyone navigating mental health, addiction, entrepreneurship, or simply trying to find balance in a chaotic world. Let's talk: If you would like to talk in confidence, please contact Gary today on: +44 7917 819 375 thegapcounselling.com @thegapcounselling - Facebook @thegapcounselling - Instagram @thegapcounselling - LinkedIn +44 7917 819375 - Whatsapp

AP correspondent Charles de Ledesma reports King Charles III has been seen in public for first time since his brief hospitalization for the side effects from his cancer treatment.

Think that colorful slushy drink is just harmless fun? It might be time to take a closer look!A 2024 study published in the Archives of Disease in Childhood investigated the effects of glycerol, a common food additive found in slushy drinks and other processed snacks. The study followed 21 children aged 2 to 7 who experienced adverse reactions after consuming these drinks. Some of the children faced low blood sugar levels and imbalances in their body's chemistry. While most recovered with proper medical care, the research highlights the importance of understanding the potential effects of certain additives.In this hot health topic episode of Accelerated Health with Sara Banta, I explore what parents need to know about glycerol and other common additives. You'll learn how to identify these ingredients, recognize signs of sensitivity, and support your child's well-being with targeted nutrition and clean eating. I'll also share practical tips on reducing exposure and choosing safer options.Knowledge is power, and small changes can make a big difference in your family's health.Supplements Featured In This Episode:• Acceleradine® Iodine https://www.acceleratedhealthproducts.com/products/acceleradine-iodine-supplement • MegaSporeBiotic™ Kids Probiotic Gummies https://www.acceleratedhealthproducts.com/products/megasporebiotic-gummies • Ola Loa ENERGY Multivitamin Drink https://www.acceleratedhealthproducts.com/products/ola-loa-energy-multivitamin-drinkNot sure what food to eat and avoid? This guide is for you.⬇️

When the systems your child depends on are under threat, it doesn't feel political—it feels personal.In this episode, Madeline and Alyssa unpack the deep unfairness of having to constantly justify your child's worth while watching essential supports unravel in real time. They also discuss the fury that bubbles up when people call your fear “political,” the heartbreak of realizing who around you doesn't care, and the exhaustion of never being allowed to rest.This isn't about debates or party lines—it's about fear, frustration, and the deep grief of feeling unsupported by those in your community.If you're feeling angry, bitter, or broken-hearted, this episode is for you.Links:Follow @margot_thebrave for more information on the situation at NIH.Listen to Ep 81: Health Anxiety.Listen to Ep 185: Medical Parent Trauma.Hear Alyssa's other episodes: 180: Does it get easier?, 179: Exhaustion, 174: Silencing, 171: Financial Strain, 170: Hospitalizations, 140: Alyssa's Story, 125: Travel w/ Disabled KidsFill out our contact form to join upcoming discussion groups!Follow Alyssa at @caffeinated_caregivers!Follow us on Instagram @the_rare_life!Donate to the podcast or Contact me about sponsoring an episode.Follow the Facebook page.Join the Facebook group Parents of Children with Rare Conditions.Access the transcript on the website here.And if you love this podcast, please leave us a rating or review in your favorite podcast app!

In this episode, Kim Fleck shares her personal journey through health challenges leading to her ileostomy. From her background as a special education teacher to her struggles with misdiagnosis and autoimmune issues, Kim's story highlights resilience and the importance of community support. She discusses her experiences with various treatments, the impact of her health on her life, and her exploration of natural remedies and dietary changes. In this conversation, the speakers delve into the misconceptions surrounding vegetarianism, the importance of self-discovery, and the transformative journey of healing through alternative medicine. They share personal stories of resilience, the significance of listening to one's body, and the power of relationships with healers. The discussion emphasizes the need for quiet reflection and the choice to spiral up in life despite challenges.TakeawaysThis is my perspective, not a prescription for others.I had no previous health issues before moving to Connecticut.I got obsessed with P90X to stay fit despite my health issues.Losing all my hair was a significant emotional challenge.Brain lesions affected only 1-2% of the population, and I was one of them.I decided to embrace my appearance and never wore a wig again.I developed a cancer imposter syndrome due to misconceptions about my health.Hospitalization led to my permanent ileostomy, which changed my life.I learned the importance of advocating for my health and choices.Dietary changes became crucial in managing my health issues. There's a lot of processed foods in vegetarian diets.Meeting Dr. Ming Wu was a turning point in my health journey.Self-discovery is crucial for healing.Listening to your body can guide your health choices.Qigong and meditation helped me find peace.Reinventing life after teaching was necessary for my growth.Healing involves building relationships with supportive healers.Vulnerability is a strength, not a weakness.You have a choice to spiral up or down in life.Knowing yourself is key to navigating health challenges.

Plus - Noise battle puts Forest Hills Stadium summer concerts in question Learn more about your ad choices. Visit podcastchoices.com/adchoices

All Minnesota GOP lawmakers in Congress joined their fellow Republicans in voting for a budget framework that includes $2 trillion in spending cuts. While it doesn't specify the programs, Republicans have targeted Medicaid and food aid programs.Tribal leaders are asking members of Congress to address funding concerns and uphold federal government's treaty obligations to tribes. Leech Lake Band of Ojibwe Secretary-Treasurer Leonard Fineday testified to a House Appropriations subcommittee Tuesday afternoon.A new report released Wednesday by the Minnesota Chamber Foundation found that nearly 60 percent of the state's total labor force and employment growth came from foreign-born workers from 2019 to 2023.Those stories and more in today's morning update. Hosted by Gracie Stockton.

Jason Evans, Ph.D. is the Dean of the College of Food Innovation and Technology (CFIT) at Johnson & Wales University, which offers baccalaureate and graduate programming in Culinary Arts, Culinary Science, Culinary Nutrition, Food and Beverage Entrepreneurship, and Sustainable Food Systems. Formerly, Dr. Evans was an Associate Professor of Agricultural Business Management at the State University of New York's College of Agriculture and Technology, Cobleskill (SUNY Cobleskill), where he also served as the Director of the Institute for Rural Vitality and Chair of the Department of Agriculture and Food Management. Before joining the SUNY Cobleskill faculty in 2009, Dr. Evans was an Assistant Research Professor at West Virginia University, where he earned a Ph.D. in Natural Resource Economics in 2007. In this episode of Food Safety Matters, we speak with Dr. Evans [47:30] about: His role as the Keynote Presenter at the 2025 Food Safety Summit in May, and what he is looking forward to at the Summit The topic of Dr. Evans' Keynote speech, “Leadership When Nothing is Easy,” and the challenges he sees with worker disengagement in the context of food safety Why it is crucial for food industry leaders to foster a sense of engagement, accountability, and collaboration among their teams Dr. Evans' experience as the Founding Dean of CFIT at JWU, and what a JWU education in food innovation and technology offers to students Topics that Dr. Evans emphasizes as a food and agriculture educator and researcher, and how he has seen the academic field evolve throughout his career Why the need for problem-solvers in the food system is greater now than ever. News and Resources News Changes happening at U.S. federal food safety regulatory agencies [3:48] Letter From 85 Congresspeople Urges End to Federal Public Health ‘Gag Order,' Addressing Bird Flu [3:48] FDA Moves to Rehire Some Human Foods Staffers Who Were Previously Fired [7:09] USDA to Invest in Farm Biosecurity, Chicken Vaccinations to Combat Avian Influenza [7:50] FDA Leader Jim Jones Resigns After 89 'Indiscriminate' Firings in Human Foods Program [8:14] Attorney Kyle Diamantas Expected to Replace Jim Jones as FDA Deputy Commissioner of Human Foods [8:34] Major Advocacy Groups Say Mass Layoffs at FDA Could Jeopardize Food Safety, 'MAHA' Agenda [8:50] RFK Jr. Confirmed as HHS Secretary; Widespread Firings Coming to FDA, CDC [9:39] Brooke Rollins Confirmed as Secretary of Agriculture, Cites 'Aggressive Plan' to Eliminate USDA Jobs [9:39] Hospitalizations, Deaths Caused by Foodborne Illnesses More Than Doubled in 2024 [19:02] Listeria Outbreak Linked to Nutritional Shakes Served at Healthcare Facilities Causes 12 Deaths [25:58] California Bill Would Set State Drinking Water Limits for PFAS in Case EPA Standards are Weakened [31:12] Food Safety Insights “Food Safety Insights” by Bob Ferguson [35:24] Regulatory Changes Impacting Your Food Safety Program, Part 1—What Should FDA's Priorities Be? Food Safety Magazine December ‘24/January '25 Regulatory Changes Impacting Your Food Safety Program, Part 2—What Should USDA's Priorities Be? Food Safety Magazine February/March ‘25 Sponsored by: CINTAS We Want to Hear from You! Please send us your questions and suggestions to podcast@food-safety.com

Tuesday, March 11 -  Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) cover a number of topics affecting our health. First up, Doug and Dr. Ken discuss some good news that flu activity has finally decreased for two consecutive weeks — and why this season's flu seems to be the worst case in decades. Continuing with viral infections, news out of the Infectious Disease Medical Journal found people who've been hospitalized with a severe case of COVID-19 are at a higher risk of death from any medical cause for up to two years after their hospitalization, and concerns continue to grow with the Avian/Bird Flu. Next, Dr. Ken shares good news about consuming fresh squeezed orange juice and why the natural sugar found in fruit is good for you, olive oil and nuts can help decrease depression risk, how poor sleep endangers your health, and what's really going on with the latest measles outbreak and recent death. Lastly, Dr. Ken answers listener questions, including nonsurgical weightless treatments like laser therapy, the healthiest time of year and what each season brings with illnesses and health issues, the most powerful exercise people should do for their overall health, and patient monitoring devices doctors are using when their patience aren't in their office. Website: GoodDayHealthShow.com Social Media: @GoodDayNetworks

In this episode, Dr. Valentin Fuster highlights a groundbreaking study on acoramides, a novel treatment for transthyretin amyloid cardiomyopathy (ATTR), which shows significant reductions in mortality and cardiovascular hospitalizations compared to a placebo. Experts discuss the clinical implications, comparing acoramides to the previously approved tafamidis, noting exciting advancements in treatments for a once-untreatable disease.

Dr. Kevin Simon (Harvard Medical School and Boston Public Health Commission) joins Dr. Dixon and Dr. Berezin to discuss the processes behind and concerns surrounding involuntary psychiatric hospitalization. Transcript 01:03     Career path 03:42     Boston Public Health Commission 09:28     Collaborators 13:09     Section 12 16:14     Transportation 17:17     Rates of involuntary transport 22:29     Requests that don't end in transport 23:42     Police involvement Subscribe to the podcast here. Check out Editor's Choice, a set of curated collections from the rich resource of articles published in the journal. Sign up to receive notification of new Editor's Choice collections. Browse other articles on our website. Be sure to let your colleagues know about the podcast, and please rate and review it wherever you listen to it. Listen to other podcasts produced by the American Psychiatric Association. Follow the journal on Twitter. E-mail us at psjournal@psych.org

Pope Francis has been hospitalized for nearly three weeks with double pneumonia. In this episode of “Inside the Vatican,” Ricardo da Silva, S.J., speaks with veteran Vatican reporter Gerard O'Connell about the pope's health, ongoing work, and the misinformation surrounding his condition. While stable, the pope's condition remains serious, and his prognosis is “guarded,” meaning he is not yet out of danger. In the second half, Ricardo asks Gerry about his recent interview with Archbishop Paul Richard Gallagher, the Vatican's foreign minister, where they discussed ongoing conflicts in Gaza and Ukraine, as well as diplomatic relations with the U.S. and China. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Armin Feldman's Pretrial Prelitigation Medical Legal Consulting Coaching Program will teach you to build your own nonclinical consulting business as a valued consultant to attorneys without doing med mal cases or expert witness work. Armin will teach you everything from business concepts to the medicine involved when launching your new consulting business during one year of unlimited coaching. For more information go to nonclinicalphysicians.com/mlconsulting/ Learn the business and management skills you need by enrolling in the University of Tennessee Physician Executive MBA program at nonclinicalphysicians.com/physicianmba. Get the FREE GUIDE to 10 Nonclinical Careers at nonclinicalphysicians.com/freeguide. Get a list of 70 nontraditional jobs at nonclinicalphysicians.com/70jobs.                                                                                                 =============== On the podcast this week, John discusses the concept of Direct Primary Care (DPC). First appearing in the early 2000's, this type of practice is characterized by the elimination of third party payers. In most cases, insurance billing is replaced by a subscription or “membership” model in which patients prepay for their care on a monthly or quarterly basis. The typical DPC practice agrees to provide a comprehensive set of outpatient services that meet the needs of most patients. Hospitalizations and high-cost surgeries are generally covered by traditional insurance. Under this model, the elimination of insurance billing results in lower overhead, less paperwork, fewer employees, and better access by expanding the use of texting, phone calls, email, and telemedicine. Office visits are generally longer and more comprehensive with less time spent on paperwork. While originally designed for primary care, there are examples of specialty-based DPC-style payment arrangements. John describes why this can be the solution to burnout and a way to recover the joy of practicing medicine while earning a very good income. He also explains that creating a DPC practice requires extensive planning and significant financial resources, but less than opening a traditional practice. And he offers his thoughts on transitioning from employment to your own DPC practice. You'll find links mentioned in the episode at nonclinicalphysicians.com/direct-primary-care-practice/

This podcast reports a severe flu season, with hospitalizations exceeding previous years and rising pediatric flu deaths. A Texas measles outbreak, mainly in unvaccinated children, has reached nearly 60 cases, with more in New Mexico, highlighting vaccine decline risks. Research finds moderate to vigorous leisure activity lowers type 2 diabetes risk, while strenuous work activity does not. A UCLA study questions Paxlovid's effectiveness in preventing COVID-19 hospitalizations in vaccinated older adults, raising cost-effectiveness concerns.

AP correspondent Laurence Brooks reports on Pope Francis' health, after he spent his 10th day in a Rome hospital.

AP correspondent Laurence Brooks reports on Pope Francis' health, after he spent his 10th day in a Rome hospital.

Statewide data from the Minnesota Department of Health shows seasonal virus hospitalizations are trending downward.Minnesota Attorney General Keith Ellison has issued a formal opinion saying organizations that comply with President Donald Trump's recent executive order banning transgender students from competing in sports consistent with their gender identity would violate state law. The guidance comes after the Minnesota State High School League asked the state office for formal advice on the matter.The first bill voted on in the Minnesota House this session didn't get enough support to pass Thursday. The Republican-sponsored bill would have declared more data from state attorney general investigations as public.

Cannabis Use Disorder Emergency Department Visits and Hospitalizations and 5-Year Mortality JAMA Network Open This cohort study of 11.6 million people who were studied for a median of five years investigated if individuals who have hospital-based (emergency department or hospitalization) care for a cannabis use disorder (CUD) were at increased risk of death. Researchers found that individuals with incident hospital-based care for a CUD were at a 2.8-fold increased risk of death within five years relative to the general population. These results suggest that individuals who require hospital-based care for a CUD may be at increased risk of premature death.   Read this issue of the ASAM Weekly Subscribe to the ASAM Weekly Visit ASAM

My Hospitalization Caused by an Autoimmune Disease Attacking My Brain by Paloma by 826 Valencia

N Engl J Med 2013;369:1587-1597N Engl J Med 2014;371:1111-1120Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.Background: In the TAPAS trial, thrombus aspiration in patients with ST elevation myocardial infarction (STEMI) improved coronary reperfusion as evident by coronary blush grade and electrocardiogram. The improvement in these surrogate endpoints was large and generated enthusiasm within the cardiology community regarding the potential of thrombus aspiration. While the trial demonstrated a trend toward improvement in clinical outcomes, this was not statistically significant and the trial was not powered for these clinical outcomes.The Thrombus Aspiration in ST-Elevation Myocardial Infarction in Scandinavia (TASTE) trial was designed to assess the impact of thrombus aspiration in patients with STEMI, and was powered to detect differences in clinical endpoints.Patients: Patients were included if they had chest pain suggestive of myocardial ischemia for at least 30 minutes but less than 24 hours before hospital admission, and if the EKG showed new ST-segment elevation or left bundle-branch block.Patients were excluded if they couldn't provide informed consent or if they needed emergency coronary artery bypass grafting.The trial enrolled patients from all 29 PCI centers in Sweden, 1 in Iceland and 1 in Denmark.Baseline characteristics: The trial randomized 7,244 patients – 3,621 randomized to thrombus aspiration and 3,623 randomized to conventional PCI.The average age of patients was 66 years and 75% were men. Approximately 42% had hypertension, 12% had diabetes, 21% had hyperlipidemia, 12% had prior myocardial infarction, and 31% were current smokers.Procedures: Patients were randomly assigned in a 1:1 ratio to undergo thrombus aspiration follow by PCI or conventional PCI. The study was open label.The use of anticoagulants during PCI was left to the discretion of the treating physician. Stenting was encouraged with the type of stent left to the discretion of the physician. The administration of P2Y12 inhibitors was also left to the discretion of the physician. Lifelong treatment with aspirin was recommended in all patients.Endpoints: The primary end point was all-cause death at 30 days. Data on mortality were obtained from the national population registry. The secondary end points, which were obtained from the SWEDEHEART registry and the national discharge registry, included 30-day rates of hospitalization for recurrent myocardial infarction, stent thrombosis, target-vessel revascularization, target-lesion revascularization, and the composite of all-cause mortality or recurrent myocardial infarction.Analysis was performed based on the intention-to-treat principle. To achieve 80% power with a two-sided alpha of 0.05, a total of 4,886 patients would be needed to detect a hazard ratio for death of at least 1.30 with PCI alone as compared with PCI plus thrombus aspiration. This calculation assumed the 30-day mortality with PCI alone to be 6.3%. Due to lower than expected mortality rate, the sample size was increased to 7,138 patients. The new sample size would detect an odds ratio for death with PCI alone as compared with PCI with thrombus aspiration of at least 1.5, assuming the 30-day mortality in the conventional PCI group to be 3.5%.Results: Out of the 11,709 patients with STEMI in Sweden or Iceland, 4,697 (40.1%) were not enrolled in the trial. Of these patients not enrolled, 1,162 (24.7%) underwent thrombus aspiration. The median time from onset of symptoms to PCI was approximately 3 hours. No patients were lost to follow up with respect to the primary outcome. Among patients assigned to thrombus aspiration, 93.9% of the patients underwent the procedure. Among patients assigned to conventional PCI, 4.9% underwent thrombus aspiration.The primary outcome of all-cause death at 30-days was similar between both treatment groups (2.8% with thrombus aspiration vs 3.0% with conventional PCI, HR: 0.94, 95% CI: 0.72 - 1.22; p= 0.63).There were no statistically significant differences in any of the secondary outcomes at 30-days (incidence for thrombus aspiration mentioned first): Hospitalization for recurrent myocardial infarction (0.5% vs 0.9%), stent thrombosis (0.2% vs 0.5%), target-vessel revascularization (1.8% vs 2.2%), target-lesion revascularization (1.2% vs 1.6%), and the composite of all-cause death or recurrent myocardial infarction (3.3% vs 3.9%).There was no difference in the incidence of stroke or neurological complications (0.5% in both groups), and no difference in the incidence of perforation or tamponade (0.4% in both groups).Authors published a 1-year follow up study. At 1-year, there was no significant difference in all-cause death (5.3% with thrombus-aspiration group vs. 5.6% with conventional PCI, HR: 0.94, 95% CI: 0.78 - 1.15; p= 0.57). Similarly, no significant differences were observed for any of the secondary endpoints (incidence for thrombus aspiration mentioned first): Hospitalization for recurrent myocardial infarction (2.7% in both groups), stent thrombosis (0.7% vs 0.9%), target-vessel revascularization (4.4% vs 4.9%), target-lesion revascularization (3.2% vs 3.5%), and the composite of all-cause death or recurrent myocardial infarction (7.7% vs 8.1%).There were no significant subgroup interactions for the primary outcome.Conclusion: In patients with ST elevation myocardial infarction, thrombus aspiration during PCI as compared to conventional PCI, did not improve the primary outcome of all-cause at 30-days. It also did not significantly reduce the secondary outcomes at 30-days which included hospitalization for recurrent myocardial infarction, stent thrombosis, target-vessel revascularization, target-lesion revascularization, and the composite of all-cause death or recurrent myocardial infarction. Results remained unchanged at 1-year.The TAPAS and TASTE trials highlight a critical lesson in research: Reliance on surrogate endpoints to guide medical practice can be misleading, even when surrogate outcomes suggest a substantial benefit, as seen in the TAPAS trial. Therefore, positive findings based on surrogate endpoints should always be validated by larger trials powered to assess clinical outcomes, before adopting them into clinical practice.The TAPAS trial did impact clinical practice, with approximately 1 in 4 patients with STEMI in Sweden during the TASTE study period, who were not enrolled in the TASTE trial, underwent thrombus aspiration.Another key takeaway is that results from smaller trials are not always replicated in larger studies. In TAPAS, thrombus aspiration was associated with a reduction in 30-day mortality, with a number needed to treat of approximately 53 patients. However, this finding was not statistically significant, raising questions about whether a larger sample size could have demonstrated a significant benefit. This assumption was refuted by the TASTE trial, highlighting the potential pitfalls of prematurely adopting interventions without robust evidence from sufficiently large trials.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

Pope Francis was admitted to the hospital on Friday, February 14 for a respiratory infection that the pope referred to as bronchitis. He underwent tests and rested over the weekend, skipping his Sunday Angelus for the first time in 12 years. The Vatican said his condition was improving on Saturday and Sunday and that the fever he entered the hospital with had gone away. A statement from the Vatican Monday morning, however, revealed that Pope Francis may need to stay in the hospital longer than originally anticipated. When the pope entered the hospital, the Vatican announced all his engagements were cancelled through Monday. This morning's statement said that the pope's test results have shown “a polymicrobial infection of the respiratory tract,” which paints a “complex clinical picture that will require an adequate hospital stay.” It was unclear how long that stay would be. Read Gerry's latest report here. Please support this podcast by becoming a digital subscriber to America Media. Learn more about your ad choices. Visit megaphone.fm/adchoices

Vice President JD Vance and Ukrainian President Volodymyr Zelensky met today amid negotiations over ending the war in Ukraine. A 28-year-old US citizen has been detained in Russia for drug possession. A storm responsible for heavy rainfall in California is moving east, putting millions under flood watch. The number of severely ill flu patients in hospitals is topping levels seen at some points of the Covid-19 pandemic. Plus, we'll tell you how the environmental industry is reacting to President Donald Trump's federal ban on paper straws. Learn more about your ad choices. Visit podcastchoices.com/adchoices

A Journey of Resilience that Leads to Advocacy In this heartfelt episode of 'Pushing Forward with Alycia,' host Alycia Anderson and her husband Marty share their personal ordeal with sepsis, a life-threatening condition that nearly cost Alycia her life. They dive into Alycia's congenital disability, sacral agenesis, her battles with chronic infections, and how a near-fatal experience with sepsis in 2019 became a pivotal moment in her life. Their story highlights the importance of early detection, the need for specialized medical care, and the incredible support of loved ones. The episode is a powerful reminder to listen to our bodies, balance work pressures, and make room for rest and self-care. The Heart of This Episode

Keywords dental infection, toothache, oral surgery, antibiotics, patient care, infection progression, surgical intervention, recovery, dental health, emergency care summary In this conversation, Dr. Serv Wahan discusses a complex case of a dental infection that began with a simple toothache and escalated into a serious condition requiring surgical intervention. He emphasizes the importance of recognizing symptoms, the risks associated with tooth infections, and the critical role of timely medical care. The discussion covers the patient's journey through various treatments, the challenges faced, and the eventual recovery, highlighting key lessons learned in dental health management. takeaways Toothaches can lead to serious infections if untreated. Recognizing symptoms early is crucial for effective treatment. Bacteria from dental infections can spread to other parts of the body. Antibiotic treatment must be monitored for effectiveness. Surgical intervention may be necessary in severe cases. Trismus can indicate a serious underlying issue. Emergency care may be required for dental infections. Patient history is important in diagnosing infections. Experience plays a vital role in assessing patient conditions. Follow-up care is essential to prevent complications. Titles From Toothache to Surgery: A Dental Journey Sound Bites "It started from a simple toothache." "This is not a normal progression." "Everything worked out great in the end." Chapters 00:00 Introduction to a Dental Infection Case 02:30 Understanding Tooth Infections and Their Risks 05:51 The Patient's Journey: From Toothache to Hospitalization

Rico is a Brooklyn, New York, resident who survived a harrowing attempt on his life orchestrated by his mother and her boyfriend. On September 4, 2022, he was shot, resulting in the loss of his left kidney and spleen. This traumatic event led to significant personal hardships, including the loss of his job, car, and apartment. Despite these challenges, Federico remains resilient, focusing on rebuilding his life and supporting his family. #TrueCrime #CrimeStory #MurderPlot #FamilyBetrayal #ShockingTruth #SurvivalStory #CrimeDocumentary #realcrimestory Thank you to MAGIC MIND & ORGAIN for sponsoring today's episode: Magic Mind: Visit https://www.magicmind.com/ianbickjan to get 45% off the Magic Mind Bundle! Orgain: For 30% off your order, head to https://Orgain.com/IANBICK and use code IANBICK.   Connect with Rico: https://www.instagram.com/therealneedacheck?igsh=aGowZXczenByMjhh&utm_source=qr Hosted, Executive Produced & Edited By Ian Bick: https://www.instagram.com/ian_bick/?hl=en https://ianbick.com/ Presented by Tyson 2.0 & Wooooo Energy: https://tyson20.com/ https://woooooenergy.com/ Buy Merch: https://www.ianbick.com/shop Use code lockedin at checkout to get 20% off your order Timestamps: 00:00:00 Welcome to Locked In: Rico's Introduction 00:04:31 Navigating Fatherhood and Parental Absence 00:09:13 Growing Up with Abandonment and Resilience 00:14:11 Discover the Benefits of High-Protein Shakes with Orgain 00:18:41 Family Betrayal and Legal Struggles 00:23:26 Family Conflict and Legal Troubles 00:27:56 Family Struggles and Financial Manipulation 00:32:27 Toxic Family Dynamics and Betrayal 00:36:57 Family Conflict and Unexpected Life Insurance Discovery 00:41:34 The Dramatic Home Intrusion and Struggle 00:46:18 False Accusations and Hospital Ordeal 00:50:45 Misunderstood and Mistreated Gunshot Victim Experience 00:55:21 Family Turmoil and Hospitalization 00:59:36 Family Silence and Isolation After Trauma 01:03:50 Surviving a Life-Threatening Experience 01:08:36 Personal Growth and Reflection 01:13:15 Farewell and Safe Travels Wishes Powered by: Just Media House : https://www.justmediahouse.com/ Creative direction, design, assets, support by FWRD: https://www.fwrd.co Learn more about your ad choices. Visit megaphone.fm/adchoices

"The most healing thing for me now has been the support of other adoptees." -- Dave Sanchez-Brown Read the transcript of this episode here: https://app.swellai.com/t/tp_01JJD8EF1R7VJ6J0V5GXRWXJY4  =============== EPISODE SUMMARY: In this episode of Unraveling Adoption, I had the privilege of speaking with Dave Sanchez-Brown, an adoptee who has bravely navigated the complexities of adoption, mental health struggles, and addiction. Dave shared his adoption story, which took a significant turn after he read Dani Shapiro's memoir Inheritance. Inspired, he decided to take a DNA test, leading him to uncover his biological family and the trauma associated with his past. He discussed the overwhelming emotions that surfaced as he connected with his roots, including the discovery of a family history marked by addiction. Throughout our conversation, Dave highlighted the importance of community and peer support in his recovery journey. He emphasized that finding others who share similar experiences has been more therapeutic than traditional therapy. We also touched on the stigma surrounding addiction and mental health, and how society often lacks empathy for those struggling. As we wrapped up, Dave offered valuable advice for adoptive parents, urging them to be aware of their children's emotional needs and the potential for feelings of alienation. He encouraged parents to seek their own healing to better support their kids. This episode is a powerful reminder of the resilience of the human spirit and the importance of connection in healing. I hope Dave's story inspires listeners to seek support and understanding, whether they are adoptees, adoptive parents, or anyone affected by mental health challenges. Thank you for joining us, and remember to stay safe and connected. ===============

(Jan 24, 2025) The death of a prison inmate has triggered a call for suite of prison reforms in the state legislature; Malone prison staff were hospitalized on Wednesday after encountering an unknown substance; Adirondack ice climbing conditions this winter; The Adirondack Diversity Initiative is launching a micro credential program for North Country businesses; and, five North Country projects will share almost $5 million dollars from the Northern Border Regional Commission.

Garth Greenwell unpacks his novel, Small Rain and Basi Affia discusses Iowa's first Black comic book publisher.

Are you sick? Know someone who is or has been? New data from the state health department shows hospital admissions for COVID-19 and RSV have increased, and flu-related hospitalizations are soaring.Twin Cities Habitat for Humanity invited the public to pay tribute to former President Jimmy Carter Thursday. The organization raised walls for community members to sign personal messages to the late president. This is a MPR News morning update, hosted by Phil Picardi. Music by Gary Meister.

Federal prosecutors say they've uncovered additional criminal conduct by Mayor Eric Adams. Plus, a New York State law that was supposed to make it more affordable for people to post bail isn't working as planned. Also, an incident at Newark landson the TSA's list of unusual items confiscated in 2024. And finally, WNYC's Michael Hill talks with Albany reporter Jon Campbell about one of Gov. Hochul's top priorities this legislative session.

Influenza cases and related hospitalizations are rising sharply in Clark County Washington. Find out how health officials are addressing the surge and what you can do to stay safe. Visit https://www.clarkcountytoday.com/news/influenza-activity-emergency-department-visits-and-hospitalizations-increasing-in-clark-county www.ClarkCountyToday.com for the full story. #Vancouver #ClarkCounty #LocalNews #Influenza #FluVaccine #PublicHealth

A daily non-partisan, conversational breakdown of today's top news and breaking news stories This Week's Sponsor: – LMNT – Free Sample Pack with any LMNT drink mix purchase | Code: MoNews – BetterHelp - 10% off your first month Headlines: – Welcome to Mo News (00:00) – Motives Behind The New Year's Day Attacks & The Military's Larger Mental Health Concerns (04:00) – U.S. Surgeon General Wants Cancer Warnings on Alcoholic Beverages (13:20) – Congress To Certify Trump's Election Victory (20:00) – Johnson Secures Speakership (23:30) – CDC Says Flu Hospitalizations “Very High” Nationwide (26:00) – What's Leading To Chinese Hospital Surge (27:50) – Blizzard and Freeze Warnings For Millions Across 30 U.S. States (29:10) – New York Begins Congestion Pricing (31:50) – Elon Musk's Starlink To Launch On United Airlines Flights By Springs (35:50) – On This Day (38:20) — Mosheh Oinounou (@mosheh) is an Emmy and Murrow award-winning journalist. He has 20 years of experience at networks including Fox News, Bloomberg Television and CBS News, where he was the executive producer of the CBS Evening News and launched the network's 24 hour news channel. He founded the @mosheh Instagram news account in 2020 and the Mo News podcast and newsletter in 2022. Jill Wagner (@jillrwagner) is an Emmy and Murrow award- winning journalist. She's currently the Managing Editor of the Mo News newsletter and previously worked as a reporter for CBS News, Cheddar News, and News 12. She also co-founded the Need2Know newsletter, and has made it a goal to drop a Seinfeld reference into every Mo News podcast. Follow Mo News on all platforms: Website: www.mo.news Instagram: https://www.instagram.com/mosheh/ Daily Newsletter: https://www.mo.news/newsletter Youtube: https://www.youtube.com/@monews Twitter: https://twitter.com/mosheh TikTok: https://www.tiktok.com/@mosheh Facebook: https://www.facebook.com/MoshehNews Snapchat: https://t.snapchat.com/pO9xpLY9

In this episode, Dr. Valentin Fuster discusses a groundbreaking study that uses machine learning to predict mortality and hospitalization risks in patients with implantable cardioverter defibrillators (ICDs). By leveraging large datasets and time-varying ICD data, the study developed a robust predictive model, though challenges remain regarding data gaps and its applicability to diverse patient populations.

N Engl J Med 2016;375:1242-1252Background: The first drug-eluting stent (DES) was approved by the FDA in 2003 following the publication of the RAVEL trial. Since then, newer generations of DES were developed and were tested in clinical trials. The majority of trials comparing DES to bare-metal stents (BMS) showed reduction in repeat revascularization with DES but no significant reduction in death or myocardial infarction. Following these publications, the use of DES grew rapidly and was used in more than two thirds of percutaneous coronary interventions (PCI) by 2010.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.These trials, however, were very selective, had short follow up time (TAXUS-IV followed patients for 9 months and SPRIT IV followed patients for 12 months), and had limited power to assess hard outcomes.The NORSTENT trial investigators sought to compare DES to BMS in a more pragmatic design and follow patients for longer time.Patients: All patients who were undergoing PCI in Norway were assessed for enrollment. Patients had stable angina or acute coronary syndrome. Lesions were in native coronary arteries or bypass grafts.Patients were excluded if they had prior coronary stents, bifurcating lesions requiring a two-stent technique or life expectancy less than 5 years due to a medical condition other than coronary artery disease. Patients were also excluded if they had contraindications to dual antiplatelets or were taking warfarin.Baseline characteristics: The trial randomized 9,013 patients – 4,504 randomized to receive a DES and 4,509 to receive a BMS.The average age of patients was 63 years and 75% were men. Approximately 42% had hypertension, 54% had hyperlipidemia, 10% had prior myocardial infarction, 7% had prior CABG, 12% had diabetes, and 35% were current smokers.The indication for PCI was stable angina in 29% of the patients, unstable angina in 12% and STEMI or NSTEMI in 58%.Procedures: The study was open-label but outcomes assessment was blinded. Patients were randomly assigned in a 1:1 ratio to receive DES or BMS. Patients could receive several stents as clinically indicated but can only receive the assigned stent type during the index procedure.In all patients, aspirin 75 mg daily was given indefinitely while clopidogrel 75 mg daily was given for 9 months.Follow up visits were done as clinically appropriate without specification from the study protocol. Similarly, no routine follow up coronary angiography was performed.Endpoints: The primary outcome was a composite of all-cause death or spontaneous myocardial infarction. Secondary outcomes included repeat revascularization, stent thrombosis, major bleeding and health status based on the Seattle Angina Questionnaire.Clinical outcomes were collected by linking each patient unique national identification number to the Norwegian national patient registry.Analysis was performed based on the intention-to-treat principle. The study planned to enroll 8,000 patients to be followed for a median of 5 years. Assuming the 5-year event rate of the primary outcome to be 17%, the study would provide 93% power to detect 3% absolute risk difference between the study groups (rate ratio: 1.18). Due to lower than expected mortality, the sample size was increased to 9,000 patientsResults: Among the 20,663 patients who were assessed for eligibility, 12,425 met inclusion criteria. Among patients who met inclusion criteria, 9,013 were randomized. Figure 1 in the manuscript provides details for excluding patients and for not randomizing patients who met eligibility criteria. The most common reason for exclusion was prior PCI.The number of stents implanted per patient was 1.7 and more than 98% received the assigned stent type. The median follow up time was 5 years.The primary composite outcome of all-cause death or nonfatal spontaneous myocardial infarction was not significantly different between both treatment arms (16.6% with DES vs 17.1% with BMS, HR: 0.98; 95% CI: 0.88 - 1.09; p= 0.66).For the secondary outcomes – Hospitalization for unstable angina was similar between treatment groups (5.2% vs. 5.7%; p= 0.21). Stent thrombosis was lower with DES (0.8% vs 1.2%; p= 0.05). Target-lesion revascularization was also lower with DES (5.3% vs 10.3%; p< 0.001). Bleeding Academic Research Consortium (BARC) 3, 4 or 5 was similar between groups (5.5% vs 5.6%; p= 0.88).There was no significant difference in health status based on the Seattle Angina Questionnaire.There were no significant subgroup interactions.Conclusion: In patients undergoing PCI, the use of DES did not reduce the composite endpoint of death or spontaneous myocardial infarction compared to BMS. Target-lesion revascularization was reduced with DES with a number needed to treat of 20 patients.The findings of this study align with the results of other trials comparing DES to BMS. We have reviewed several key trials and included links to additional studies in this field below. Overall, DES significantly reduce target-lesion revascularization without significant effect on all-cause mortality or myocardial infarction.An important consideration in this and other related trials is that both stent types were studied using similar durations of dual antiplatelet therapy (DAPT) following PCI. For patients with stable angina, BMS typically require only one month of DAPT, while DES often necessitate three to twelve months. Since shorter durations of DAPT are generally safer for patients, a trial comparing DES with three to twelve months of DAPT compared to BMS with one month of DAPT would be insightful.A final teaching point is that less than 50% of screened patients were ultimately enrolled in this pragmatic trial, which had minimal exclusion criteria. It's not uncommon for trials to enroll less than 5% of screened patients which limits their external validity.* Other trials of DES vs BMShttps://pubmed.ncbi.nlm.nih.gov/21080780/https://pubmed.ncbi.nlm.nih.gov/22951305/Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

We are back with more exciting IDWeek 2024 content. In this episode, Breakpoints hostesses Drs. Erin McCreary, Julie Ann Justo, Jeannette Bouchard, and Megan Klatt highlight more of our favorite sessions and posters at IDWeek, this episode is a must listen if you are an IDWeek nerd like us! References: Perret et al. Application of OpenAI GPT-4 for the retrospective detection of catheter-associated urinary tract infections in a fictitious and curated patient data set. 10.1017/ice.2023.189 Wiemken et al. Assisting the infection preventionist: Use of artificial intelligence for health care–associated infection surveillance. 10.1016/j.ajic.2024.02.007 Leekha et al. Evaluation of hospital-onset bacteraemia and fungaemia in the USA as a potential healthcare quality measure: a cross-sectional study. 10.1136/bmjqs-2023-016831 Diekema et al. Are Contact Precautions "Essential" for the Prevention of Healthcare-associated Methicillin-Resistant Staphylococcus aureus? 10.1093/cid/ciad571 Martin et al. Contact precautions for MRSA and VRE: where are we now? A survey of the Society for Healthcare Epidemiology of America Research Network. 10.1017/ash.2024.350 Browne et al. Investigating the effect of enhanced cleaning and disinfection of shared medical equipment on health-care-associated infections in Australia (CLEEN): a stepped-wedge, cluster randomised, controlled trial. 10.1016/S1473-3099(24)00399-2 Protect trial: Decolonization in Nursing Homes to Prevent Infection and Hospitalization. 10.1056/NEJMoa2215254 Aldardeer et al. Early Versus Late Antipseudomonal β-Lactam Antibiotic Dose Adjustment in Critically Ill Sepsis Patients With Acute Kidney Injury: A Prospective Observational Cohort Study. 10.1093/ofid/ofae059 Schmiemann et al. Effects of a multimodal intervention in primary care to reduce second line antibiotic prescriptions for urinary tract infections in women: parallel, cluster randomised, controlled trial. 10.1136/bmj-2023-076305 Vernacchio et al. Improving Short Course Treatment of Pediatric Infections: A Randomized Quality Improvement Trial. 10.1542/peds.2023-063691 Advani et al. Bacteremia From a Presumed Urinary Source in Hospitalized Adults With Asymptomatic Bacteriuria. 10.1001/jamanetworkopen.2024.2283 Saif et al. Clinical decision support for gastrointestinal panel testing. 10.1017/ash.2024.15 Bekker et al. Twice-Yearly Lenacapavir or Daily F/TAF for HIV Prevention in Cisgender Women. 10.1056/NEJMoa2407001 Montini et al. Short Oral Antibiotic Therapy for Pediatric Febrile Urinary Tract Infections: A Randomized Trial. 10.1542/peds.2023-062598 Nielsen et al. Oral versus intravenous empirical antibiotics in children and adolescents with uncomplicated bone and joint infections: a nationwide, randomised, controlled, non-inferiority trial in Denmark. 10.1016/S2352-4642(24)00133-0 Kaasch et al. Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial. 10.1016/S1473-3099(23)00756-9 AMIKINHAL: Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia. 10.1056/NEJMoa2310307 PROPHY-VAP: Ceftriaxone to prevent early ventilator-associated pneumonia in patients with acute brain injury: a multicentre, randomised, double-blind, placebo-controlled, assessor-masked superiority trial. 10.1016/S2213-2600(23)00471-X AVENIR: Azithromycin to Reduce Mortality — An Adaptive Cluster-Randomized Trial. 10.1056/NEJMoa2312093 Thomas et al. Comparison of Two High-Dose Versus Two Standard-Dose Influenza Vaccines in Adult Allogeneic Hematopoietic Cell Transplant Recipients. 10.1093/cid/ciad458 Schuster et al. The Durability of Antibody Responses of Two Doses of High-Dose Relative to Two Doses of Standard-Dose Inactivated Influenza Vaccine in Pediatric Hematopoietic Cell Transplant Recipients: A Multi-Center Randomized Controlled Trial. 10.1093/cid/ciad534 Mahadeo et al. Tabelecleucel for allogeneic haematopoietic stem-cell or solid organ transplant recipients with Epstein-Barr virus-positive post-transplant lymphoproliferative disease after failure of rituximab or rituximab and chemotherapy (ALLELE): a phase 3, multicentre, open-label trial. 10.1016/S1470-2045(23)00649-6 Khoury et al. Third-party virus-specific T cells for the treatment of double-stranded DNA viral reactivation and posttransplant lymphoproliferative disease after solid organ transplant. 10.1016/j.ajt.2024.04.009 Spec et al. MSG-15: Super-Bioavailability Itraconazole Versus Conventional Itraconazole in the Treatment of Endemic Mycoses—A Multicenter, Open-Label, Randomized Comparative Trial. 10.1093/ofid/ofae010

A Decade of Defying Darkness: My Journey from Hospitalization to Hope In this special once-in-a-lifetime bonus episode, Paris reflects on her profound journey spanning the last decade since her psychiatric hospitalization on December 19, 2014. The episode is filled with raw emotions, deep introspection, and invaluable lessons learned from her battle with bipolar disorder. Through personal anecdotes, Paris shares her transformation from a patient to an advocate and public speaker, detailing her work in mental health advocacy and how she's used her experiences to inspire and support others. Paris emphasizes the importance of community, resilience, and self-improvement while also encouraging listeners to engage with her ongoing mission to spread hope and understanding. Key topics include overcoming trauma, the journey of self-discovery, the impact of supportive relationships, and the continuous effort to make a positive difference in the world. Connect with Paris's newsletter for big news coming soon ... Thank you for 100 reviews, leave one here for my book! 00:00 Introduction and Special Announcement 00:45 Reflecting on a Decade: From Hospitalization to Hope 02:51 The Power of Sharing and Community 06:06 Overcoming Trauma and Finding Purpose 10:13 Milestones and Achievements 14:14 Career Shifts and Personal Growth 19:49 Current Life and Future Plans 26:54 Final Thoughts and Gratitude

In this podcast, Dr. Valentin Fuster discusses a study on the significant impact of seasonal influenza on mortality and hospitalizations among patients with heart failure. The research highlights that influenza is responsible for substantial excess deaths and hospitalizations in this vulnerable group, emphasizing the need for better vaccination uptake and preventive measures to reduce these risks.

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Justin Boyle and Emily Hughes discuss two recent papers - the effect of dietary sodium on blood pressure and the role of decolonization in nursing homes to prevent infection. Two papers, here we go!Effect of Dietary Sodium on Blood Pressure (0:00 – 10:05).Decolonization in Nursing Homes to Prevent Infection and Hospitalization (10:05 – 20:45).And for the Good Stuff:What Do Trainees Want? The Rise of House Staff Unions (20:45 – 22:48).Initiation of opioid agonist therapy after hospital visits for opioid poisonings in Ontario (22:48 – 24:39)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

In this episode, Dr. Valentin Fuster delves into the latest research surrounding the use of the mitral clip for patients with severe functional mitral regurgitation, comparing the results of three major trials: the French MITRA-FR trial, the American COAPT trial, and the Reshape HF 2 trial. While the COAPT and Reshape HF 2 trials show positive outcomes, especially in reducing hospitalizations and improving heart failure symptoms, the French trial saw no benefit, prompting debate over the influence of left ventricular volume and disease severity on treatment success, with expert opinions calling for further studies and individualized meta-analyses.

Hola Pendejas! In this episode of Noche de Pendejadas, Miranda Rae Talks All: Childhood, Bullying, Hospitalizations, CHISME & MORE! Thanks to my sponsors: Alma can help you find the right therapist for you — not just anyone. Visit https://helloalma.com/ALAN to get started and schedule a free consultation today. • Don't forget to subscribe to the podcast for free wherever you're listening or by using this link: https://bit.ly/NochedePendejadasPodcast • If you like the show, telling a friend about it would be helpful! You can text, email, Tweet, or send this link to a friend: https://bit.ly/NochedePendejadasPodcast Follow Alannized on IG Follow Alannized on TikTok Follow Alannized on Twitter  Learn more about your ad choices. Visit podcastchoices.com/adchoices

On this episode, Tony Brueski digs into the latest bombshell from Jamie Foxx's new Netflix special, What Had Happened Was. Foxx's recent comments sparked a firestorm of controversy, with some alleging that he implicated Sean "Diddy" Combs in his mysterious 2023 hospitalization and hinted at FBI involvement. With multiple witnesses sharing conflicting interpretations of Foxx's words—was it comedy, confession, or something in between? Brueski delves deep into the evolving narrative, exploring Diddy's response, legal troubles, and the tangled relationships that brought this story into the public eye.  Want to listen to ALL of our podcasts AD-FREE? Subscribe through APPLE PODCASTS, and try it for three days free: https://tinyurl.com/ycw626tj Follow Our Other Cases: https://www.truecrimetodaypod.com The latest on The Downfall of Diddy, The Trial of Karen Read, The Murder Of Maddie Soto, Catching the Long Island Serial Killer, Awaiting Admission: BTK's Unconfessed Crimes, Delphi Murders: Inside the Crime, Chad & Lori Daybell, The Murder of Ana Walshe, Alex Murdaugh, Bryan Kohberger, Lucy Letby, Kouri Richins, Malevolent Mormon Mommys, The Menendez Brothers: Quest For Justice, The Murder of Stephen Smith, The Murder of Madeline Kingsbury, The Murder Of Sandra Birchmore, and much more! Listen at https://www.truecrimetodaypod.com

On this episode, Tony Brueski digs into the latest bombshell from Jamie Foxx's new Netflix special, What Had Happened Was. Foxx's recent comments sparked a firestorm of controversy, with some alleging that he implicated Sean "Diddy" Combs in his mysterious 2023 hospitalization and hinted at FBI involvement. With multiple witnesses sharing conflicting interpretations of Foxx's words—was it comedy, confession, or something in between? Brueski delves deep into the evolving narrative, exploring Diddy's response, legal troubles, and the tangled relationships that brought this story into the public eye.   Want to listen to ALL of our podcasts AD-FREE? Subscribe through APPLE PODCASTS, and try it for three days free: https://tinyurl.com/ycw626tj Follow Our Other Cases: https://www.truecrimetodaypod.com The latest on The Downfall of Diddy, The Trial of Karen Read, The Murder Of Maddie Soto, Catching the Long Island Serial Killer, Awaiting Admission: BTK's Unconfessed Crimes, Delphi Murders: Inside the Crime, Chad & Lori Daybell, The Murder of Ana Walshe, Alex Murdaugh, Bryan Kohberger, Lucy Letby, Kouri Richins, Malevolent Mormon Mommys, The Menendez Brothers: Quest For Justice, The Murder of Stephen Smith, The Murder of Madeline Kingsbury, The Murder Of Sandra Birchmore, and much more! Listen at https://www.truecrimetodaypod.com

Wallo Opens Up About Betrayal, Grooming, Hospitalization, Inmate Dating Profiles + MoreSee omnystudio.com/listener for privacy information.