POPULARITY
42 episodes with paxlovid
16 episodes with paxlovid
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10 episodes with paxlovid
6 episodes with paxlovid
6 episodes with paxlovid
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9 episodes with paxlovid
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7 episodes with paxlovid
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Contributor: Jorge Chalit-Hernandez, OMS3 Educational Pearls: CYP enzymes are responsible for the metabolism of many medications, drugs, and other substances CYP3A4 is responsible for the majority Other common ones include CYP2D6 (antidepressants), CYP2E1 (alcohol), and CYP1A2 (cigarettes) CYP inducers lead to reduced concentrations of a particular medication CYP inhibitors effectively increase concentrations of certain medications in the body Examples of CYP inducers Phenobarbital Rifampin Cigarettes St. John's Wort Examples of CYP inhibitors -azole antifungals like itraconazole and ketoconazole Bactrim (trimethoprim-sulfamethoxazole) Ritonavir (found in Paxlovid) Grapefruit juice Clinical relevance Drug-drug interactions happen frequently and often go unrecognized or underrecognized in patients with significant polypharmacy A study conducted on patients receiving Bactrim and other antibiotics found increased rates of anticoagulation in patients receiving Bactrim Currently, Paxlovid is prescribed to patients with COVID-19, many of whom have multiple comorbidities and are on multiple medications Paxlovid contains ritonavir, a powerful CYP inhibitor that can increase concentrations of many other medications A complete list of clinically relevant CYP inhibitors can be found on the FDA website: https://www.fda.gov/drugs/drug-interactions-labeling/drug-development-and-drug-interactions-table-substrates-inhibitors-and-inducers References Glasheen JJ, Fugit RV, Prochazka AV. The risk of overanticoagulation with antibiotic use in outpatients on stable warfarin regimens. J Gen Intern Med. 2005;20(7):653-656. doi:10.1111/j.1525-1497.2005.0136.x Lynch T, Price A. The effect of cytochrome P450 metabolism on drug response, interactions, and adverse effects. Am Fam Physician. 2007;76(3):391-396. PAXLOVID™. Drug interactions. PAXLOVIDHCP. Accessed March 16, 2025. https://www.paxlovidhcp.com/drug-interactions Summarized & Edited by Jorge Chalit, OMS3 Donate: https://emergencymedicalminute.org/donate/
Wednesday briefing: Trump's speech to Congress, fact-checked; Zelensky's partial ceasefire offer; U.S. tariffs; Paxlovid; and moreRead today's briefing.If you're not a subscriber, click here to start.
In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the downfall of public health from “postponement” of the advisory committee on immunization practices and the FDA VRBPAC influenza strain selection meetings to how the communication pause prevents public notice of NIH study section meetings, and withdrawal of CDC promotions for the ‘flu vaccine' before discussing the end of Ebola outbreak in Uganda, funding from Saudi Arabia for polio eradication, the continuing and growing measles outbreak in the US including misinformation from the Secretary of HHS, highly pathogenic avian flu and its economic effect, ie the cost of eggs before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration, provides information for Columbia University Irving Medical Center's long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and FDA approval of adjuvanted Novovax COVID vaccine. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Phantom ACIP (CDC) Postponement of ACIP…..hummmm (STATNews) Influenza Strain selection VRBPAC cancelled (Reuters) How NIH funded research is impacted by government communication pause (NY Times) Can be reviewed but still no money (STATNews) Final push to end Ebola in Uganda (WHO Uganda) Saudi Arabia sponsors polio eradication effort (GPEI)) $500 million from Saudi Arabia to immunize 370 million children against polio (CIDRAP) Measles 124 in Texas…. (Texas Health and Human Services) A Texas child who was not vaccinated has died of measles(AP News) The Measles book-(Apple Books) Measles vaccination protects against virus infection and other infections (Science) Measles deadliest sequelae (MEDPAGE TODAY) Measles cases and outbreaks (CDC Measles) Unvaccinated Child Dies of Measles in Texas Outbreak(NY Times) Texas child is first reported US measles death in a decade as outbreak hits more than 130 (Reuters) Trump's cabinet meeting: Kennedy Shocker “Not unusual”……..seriously! (YouTube) First measles death reported in Texas as Kennedy downplays the outbreak (NBC News) Measles cliff notes: symptoms timeline (Substackdn) Annual state immunization report (Texas Health and Human Services) Measles imported into Kentucky…….no tariffs? (Commonwealth of Kentucky) Egg shortage affect flu shots? (MEDPAGE TODAY) Which Came First, the Chicken Slaughter or the Egg Shortage(Wall Street Journal) Avian Influenza in Birds: Causes and How It Spreads (CDC Avian Influenza) Agriculture Secretary Brooke Rollins: My Plan to Lower Egg Prices (Wall Street Journal) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Weekly US influenza surveillance report (CDC FluView) US respiratory virus activity (CDC Respiratory Illnesses) Trump administration yanks CDC flu vaccine campaign(NPR) RSV-Network (CDC Respiratory Syncytial virus Infection) New wild to mild campaign drives key message to tame flu and reset expectations (CDC Influenza) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Effectiveness of the original monovalent messenger RNA Coronavirus Disease 2019 (COVID-19) vaccination series against hospitalization for COVID-19–Associated venous thromboembolism (JID) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Demographic variation in US outpatient hydroxychloroquine and ivermectin use during the COVID-19 pandemic (HealthAffairs) Paxlovid update (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Alleviation of COVID-19 symptoms and reduction in healthcare utilization among high-risk patients treated With nirmatrelvir/ritonavir (NMV/R) (CID) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Interventions for Long COVID: A Narrative Review (Journal of General Internal Medicine) COVID-19 vaccination and odds of post–COVID-19 condition symptoms in children aged 5 to 17 Years (JAMA Network) Novavax COVID-19 vaccine, adjuvanted (FDA) Letters read on TWiV 1196 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
This podcast reports a severe flu season, with hospitalizations exceeding previous years and rising pediatric flu deaths. A Texas measles outbreak, mainly in unvaccinated children, has reached nearly 60 cases, with more in New Mexico, highlighting vaccine decline risks. Research finds moderate to vigorous leisure activity lowers type 2 diabetes risk, while strenuous work activity does not. A UCLA study questions Paxlovid's effectiveness in preventing COVID-19 hospitalizations in vaccinated older adults, raising cost-effectiveness concerns.
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In his weekly clinical update, Dr. Griffin and Vincent Racaniello reminiscence about Dickson before discussing discharging Ebola patients, another announcement of emergency measures to control polio spread and the third nOPV2 vaccination campaign in Gaza in less than 6 months, the measles outbreak in the US, vaccination campaign for chickens against high pathogenic avian flu before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center's long COVID treatment center, and where to go for answers to your long COVID questions. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode In memory of Dickson (NY Times) All Ebola patients discharged in Uganda (DG Alerts) Uganda discharges Ebola patients (WHO Uganda) Emergency measures to stop polio…..isn't this the same plan as last year? (GPEI)) A third nOPV2 campaign…..but I thought OPV stops transmission (Reuters) Worst outbreak of measles in 30 years for Texas….go big or go home! (AP News) Measles 58 in Texas…. (Texas Health and Human Services) High pathogenic avain influenza virus infection of indoor domestic cats (CDC MMWR) Avian influenza in dairy cattle in Arizona (AZEIN) Third avian flu spillover! (CIDRAP) No vaccine hesitancy in chickens…..vaccinate all! (Science) Zoetis to supply conditionally licensed avian influenza H5N1 vaccine for chickens (Zoetis) High path avian influenza in mammals (USDA: Animal and plant health inspection service) How to vaccinate your chicken (WikiHow) Vaccine failure due to poor administration.(the poultry site) Human cases of H5N1 in US rise to 4 (CBS News) Canada's buying vaccine as US rats become infected (CIDRP) Canada purchases avian influenza vaccine for those at high risk (Canada Public Health) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) How the communications pause endangered us about influenza (AP News) Most intense flu season in 15 years (AP News) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Weekly US influenza surveillance report (CDC FluView) RSV-Network (CDC Respiratory Syncytial virus Infection) US respiratory virus activity (CDC Respiratory Illnesses) COVID-19 case fatality rate and infection fatality rate from 2020 to 2023 (Journal of Infection and public health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Paxlovid update (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) A randomized, double-blind, Phase 1, single- and multiple-dose placebo-controlled study of the safety and pharmacokinetics of IN-006, an inhaled antibody treatment for COVID-19 in healthy volunteers (eBioMedicine) Ensitrelvir for the Treatment of Nonhospitalized Adults with COVID-19 (CID) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Letters read on TWiV 1194 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss confirmation of Robert F Kennedy as HHS sectary, mpox, Ebola, how the American people support vaccine development and administration, the measles outbreak in the US-Texas, Georgia and influenza: the number of human infections, high avian flu in mammals, house cats and dairy cows before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center's long COVID treatment center, where to go for answers to your long COVID questions, how long COVID varies between children and adults and if viral infection reduces telomere length in sperm. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Confirmation of RFK, Jr as HHS sect (NY Times) Did you know mpox in NY?….(Reuters) Mpox in sex workers in the Congo and in NY (CIDRAP) 9 confirmed, 265 suspected Ebola cases in Uganda (AP news) WHAT!? Support vaccines: availability and development. WHAT? (Businesswire) Measles rising in the unvaccinated. You mean the vaccines does something positive? (ABC News) Measles in Texas….go big or go home (Texas Health and Human Services) Vaccination Conscientious exemptions in Texas (Texas Health and Human Services) 2, 6, 14 measles hospitalizations in Texas (CNN) Decreases in childhood vaccinations SchoolVaxView(CDC) 2 when 24 cases of measles in two weeks (Texas Health and Human Services) Measles in small town Texas (NY Times) Measles in the US Texas, Georgia, Rhode Island, New York, New Mexico: Elimination of measles (JID) Influenza taxonomy (NCBI) H5N9 in commercial duck farm, California (American Animal Hospital Association) Second type of bird flu circulating in ducks (Scientific Amercia) Variant H1N2 flu in Iowa (CIDRAP) All types of influenza (CDC Influenza) Bird flu in the zoos: Bronx and Queens (Gothamist) High path avian influenza in mammals (USDA: Animal and plant health inspection service) Bird flu in house cats…..I tawt I taw a puddy tat (KFF Health News) New strain of influenza in dairy cows (AP News) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) How the communications pause endangered us about influenza (AP News) Most intense flu season in 15 years (AP News)US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Weekly US influenza surveillance report (CDC FluView) RSV-Network (CDC Respiratory Syncytial virus Infection) 10 year surveillance of RSV hospitalization in adults(JID) Seasonality of RSV: 2017-2023(CDC: MMWR) What doctors wish patients know about RSV (AMA) US respiratory virus activity (CDC Respiratory Illnesses) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Paxlovid update (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Proportion of Long COVID incidence in adults and children (CID) SARS-CoV-2 infection effects sperm telomere length (Journal of Assisted Reproduction and Genetics) Pediatric gastrointestinal tract outcomes during the postacute phase of COVID-19c] (JAMA Network) Letters read on TWiV 1192 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information and aid mechanisms such as the return of MMWR, the largest tuberculosis outbreak in the US ever, lack of USAID in fighting Marburg and Ebola outbreaks in Africa, discussing if avian influenza virus is airborne, how eggs are effected and the emergence of second spillover into dairy cattle, how the difference between nOPV2 and Sabin OPV2 is a minor reduction in the association of vaccine associated paralytic poliomyelitis before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center's long COVID treatment center, where to go for answers to your long COVID questions, how children may be affected by long COVID and if SARS-CoV-2 and other inflammatory syndromes increase the risk of Alzheimer's disease. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode The return of MMWR (CDC) Largest tuberculosis outbreak ever in the US (Kansas Department of Health and Environment) Marburg virus outbreak in Tanzania (Doctors without borders) No USAID, Ebola outbreak in Uganda spreads (CBS News) WHO accelerates efforts to Ebola response in Uganda (WHO: Uganda) Global partners enable access to vaccine and treatment for Ebola outbreak in Uganda (WHO) Ventilation and respiratory viruses (CDC National Institute for Occupational safety and health) Is bird flu flying through the air…..is the virus literally airborne? (NY Times) Is bird flu like measles (American Journal of Epidemiology) Indoor safety guideline (Herokuapp) Dairy herds in Nevada have influenza! (CIDRAP) Do your eggs have H5N1? (NY Times) New genotye D1.1 of avian flu in dairy cattle(USDA Animal and Plant Health Inspection Service) Second spillover of avian flu into dairy cattle….does this story sound familiar? (CIDRAP) Impact of using nOPV2 in mass vaccination campaigns? (JID) Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) As flu increases so do deaths in kids (CIDRAP) People most impacted by respiratory viruses (CDC) Co-infection with SARS-CoV-2 and influenza A/B (BMC Infectious Diseases) Oseltamivir reduces 30-Day mortality in older adults with Influenza (OFID) RSV: Waste water scan for 11 pathogens (WastewaterSCan) RSV-Network (CDC Respiratory Syncytial virus Infection) US respiratory virus activity (CDC Respiratory Illnesses) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Paxlovid update (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long COVID Recovery Program with Zara Dureno, BA, MOT Long COVID pevalence and associated activity limitation in US children (JAMA Pediatrics) Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection (Nature Medicine) Letters read on TWiV 1190 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
It's been five years since the first laboratory-confirmed case of COVID-19 in the U.S., a bleak milestone in the early days of a pandemic that touched the lives of everyone. For the lucky ones, the virus mainly meant more precautions: mask-wearing, the occasional COVID test. But for others, a COVID-19 infection turned into long COVID. This is a chronic condition that lingers long after a COVID infection, and can reduce one's ability to live their day-to-day life.It's been estimated that about 400 million people worldwide have had long COVID. Some researchers say that number is much higher. But there's a lack of research on successful treatments for long COVID.Some patients living with the condition have taken things into their own hands. A recent investigation documented the experiences of 13 long COVID patients who tried taking Paxlovid for longer than the typical 5-day course. The patients had mixed results, adding to a growing body of evidence that there will not be one silver bullet for treating the condition.Joining Ira to talk about the results are two authors of the study, who have both had long COVID for years: Dr. Alison Cohen, assistant professor of epidemiology and biostatistics at the University of California San Francisco, and Dr. Julia Moore Vogel, senior program director at Scripps Research in La Jolla, California.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
In his weekly clinical update, Dr. Griffin and co-host Vincent Racaniello lament about the public changes from withdrawing from the WHO to health and scientific communication pauses by the Trump Administration after a brief discussion of Marburg in Tanzania and mpox in England before reviewing cats and bird flu, the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center's long COVID treatment center, and where to go for answers to your long COVID questions. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Tanzania confirms Marburg virus outbreak (Reuters) Clade Ib mpox in England (Reuters) Withdrawing from the World Health Organization (WhiteHouse) Fees costs behind withdrawing from WHO ….is that what we are suppose to believe? (Sky News) Sorry to see you go, US? (WHO) Where are the updates? (CDC Health Alert Network) Pause in health communications of all kind (Washington Post) NIH chaos…..streaming to a halt? (STAT News) Devastation at the NIH, hiring traveling, meetings, communications(Science) Protect your cat from bird flu (NPR) No communication and cats with bird flu….does not sound good (CIDRAP) Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Baloxavir marboxil for prophylatix against influenza(NEJM) Comparative effectiveness of baloxavir marboxil and oseltamir treatment for reducint household transmission of influenza (Influenza and other respiratory viruses) RSV: Waste water scan for 11 pathogens (WastewaterSCan) RSV-Network (CDC Respiratory Syncytial virus Infection) US respiratory virus activity (CDC Respiratory Illnesses) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) Host-microbe multiomic profiling identifies distinct COVD-19 immune dysregulation in solid organ transplant recipients (Nature Communications) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19 (Signal Transduction and Targeted Therapy) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long COVID Recovery Program with Zara Dureno, BA, MOT Letters read on TWiV 1186 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
This episode of Going anti-Viral features an IAS–USA Dialogue titled "Latest Update on Urgent Viral Outbreaks," a panel discussion held on January 15, 2025. This IAS-USA Dialogue is a must listen as our distinguished panel of infectious diseases experts dives deep into some of the most pressing public health challenges facing the world today. Moderated by Carlos del Rio, MD, a Distinguished Professor of Medicine in the Division of Infectious Diseases at Emory University School of Medicine, this Dialogue brings together world-class experts Yvonne Maldonado, MD, Peter Chin-Hong, MD, and Jason Zucker, MD, to discuss the latest news on urgent and emerging viral outbreaks, including mpox, avian flu (H5N1), respiratory syncytial virus (RSV), measles, human metapneumovirus, and COVID-19/long COVID.The panel also reflects on the alarming erosion of public trust in public health experts, which has been compounded by misinformation and the long-term effects of the COVID-19 pandemic. 0:00 – Introduction 2:27 – Update on mpox including treatment options11:09 – Discussion of avian flu (H5N1), influenza, and vaccination in human and animals27:36 – Impact of avian flu (H5N1) on dairy and other agriculture industries and the role of public health in supporting the economy32:47 – Impact of recent study on Tamiflu in treatment recommendations and discussion of Biloxivir37:37 – Update on COVID-19 – vaccination, treatment with Paxlovid, other treatment options, and long COVID48:27 – Recent updates on respiratory syncytial virus (RSV) and vaccination 52:03 – Discussion of human metapneumovirus54:25 –Impact of misinformation on the reduction in measles vaccinations and the health risks of measles to the population at large 59:54 – Concluding remarks__________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...
“Active holistic therapy” for prostate cancer with diet and fish oil helps defer need for surgery, hormone blockade, radiation; Why 70 is the new 60; Long-term harmful effects of acid-blockers; Do memory supplements pass the blood-brain barrier? Fish oil, krill oil, olive oil for cardiovascular prevention; Paxlovid aggressively promoted but overprescribed for otherwise healthy patients.
In his weekly clinical update, Dr. Griffin discusses how vaccination and vaccine hesitancy affects public health and disease spread in terms of mpox, the first human death from H5N1 in US, why one should not feed their pets raw pet food and the metapneumonia outbreak in China before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, how nirmatrelvir-ritonavir/Paxlovid reduces adverse outcomes of COVID in patients with kidney disease, provides information for Columbia University Irving Medical Center's long COVID treatment center, SARS-CoV-2 infection affects skin conditions including shingles and if long antiviral treatment affects long COVID. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Mpox vaccination hesitancy, previous immunisation coverage, and vaccination readiness in the African region (eClincial Medicine) Global prevalence and correlates of mpox vaccine acceptance and uptake (Communications Medicine) First case of new mpox variant in France (Reuters) First “Bird flu” death in US (NY Times) Emerging threat of H5N1 to human health (NEJM) Don't feed your pets raw food (County of Los Angeles Public Health) Oregon, nationwide raw pet food recall (CIRAP) Raw cat food avian flu, is this like raw milk? (CIDRAP) Human metapneumovirus surging in China (The Guardian) Viral video of viral chaos: human metapneumovirus in Chinese hospital (The Economic Times) Human metapneumovirus in China (NY Times) Acute respiratory infections including human metapneumovirus in northern hemisphere (WHO) Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) RSV: Waste water scan for 11 pathogens (WastewaterSCan) RSV-Network (CDC Respiratory Syncytial virus Infection) US respiratory virus activity (CDC Respiratory Illnesses) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) The effect of nirmatrelvir-ritonavir on short- and long-term adverse outcomes from COVID-19 among patients with kidney disease (OFID) Paxlovid tied to lower risk of hospital stay, heart problems, death in adults with kidney disease and COVID (CIDRAP) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) Chronic urticaria, vitiligo, alopecia areata, and herpes zoster following COVID-19 infection (Journal of Dermatology) Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID: (Communications Medicine) Letters read on TWiV 1182 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Raman Sehgal, Founder & Global President at ramarketing & Host of Molecule to Market. For this milestone episode, your host is Molecule to Market's first guest from back in 2020, JoyL Silva, Customer Engagement Lead for the US Primary Care portfolio at Pfizer, who discusses the pharmaceutical and biotechnology supply chain with Raman Sehgal covering: Raman reflects on the podcast's evolution, from its inception during COVID-19 to becoming a globally recognized platform They discuss key trends in the pharma outsourcing sector and the impact of guests who have contributed to the podcast's success Raman shares highlights from his career, including the growth of his companies, ramarketing and Lead Candidate, and his private equity ventures Insights into balancing work and family life, with advice on being present and managing priorities A desert island question where Raman chooses which podcast guests he'd bring along, plus behind-the-scenes stories of challenges and humorous incidents JoyL Silva is the Customer Engagement Lead for Pfizer's US Primary Care portfolio, overseeing sales and account management across therapeutic areas such as Migraine, Cardiovascular, Anti-virals, and Vaccines. She leads high-performing teams that drive a $20B portfolio through agile methodologies and talent development. With over 20 years at Pfizer, JoyL has excelled in commercial leadership, business transformations, and operational expertise, delivering impactful results across multiple roles, including VP for Hematology and Biosimilars, General Manager of Pfizer CentreOne, and US/Global Commercial Lead for PAXLOVID, where she spearheaded global strategies and partnerships for Pfizer's COVID-19 antiviral therapeutic. JoyL frequently speaks at industry forums and contributes her expertise to various publications and professional boards, including the Pharma & Biopharma Outsourcing Association. Her accolades include being named to the Medicine Maker Power List and PharmaVOICE 100 Most Inspiring People in the Life Sciences Industry, as well as receiving awards such as the Scrip Best Partnership Alliance Award and Putnam Media Top 20 Influential Women in Manufacturing. Her career reflects a strong commitment to driving innovation and fostering leadership in the life sciences sector. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.
Children raised on farms or with pets appear to have a lower risk of allergies due to early gut microbiota differentiation, as highlighted by a study from the Farm Flora Birth Cohort. Managing food allergies durin travel remains challenging, with a global survey showing inconsistent airline policies and unmet preventive measures. FDA trials indicate that resistance to Paxlovid in mild to moderate COVID-19 cases is rare. Lastly, the FDA has updated the Healthy Nutrient Content Claim to encourage healthier food options by promoting reformulation by manufacturers and developing a "healthy" symbol for consumer ease.
This week, the Maier's get together amidst an outbreak of COVID in the family. Topics include: Penticton airport, sickness spreads, Paxlovid, Christmas tradition, carolling at the Lakeside, Christmas' past, SOW, a different Christmas, and Christmas nostalgia. Reach Us: @kmaemaier @chrismaierbc @hwywhoney hwywhoney@gmail.com
Dr. Geeta Sood joins Department of Health Commissioner Dr. James McDonald and Executive Deputy Commissioner Johanne Morne to discuss the growing public health concern of Long COVID, highlighting the need for comprehensive care and ongoing research.They explore the diverse range of symptoms associated with Long COVID, from brain fog to POTS, and the need for a comprehensive, multidisciplinary approach to management and care. The conversation also covers the effects of vaccination and antiviral therapies, such as Paxlovid, in helping to reduce the risk of developing Long COVID after a COVID-19 infection.The Department of Health will also be holding a Commissioner's Medical Grand Rounds on Long COVID on October 13, 2024 at noon - you must register to attend: https://forms.office.com/g/Eus28gsTfkIf you have an idea for topics we should discuss, please let us know: PublicHealthNowPodcast@health.ny.gov
Welcome to season 2 episode 6 of A Friend for the Long Haul - A Long Covid Podcast! This episode features my friend, Laura Thomas. Laura and I met in an Austin, Texas-based long covid support group, and started talking when she found out that I had moved from Texas because I discovered that my MCAS symptoms improved out of state. Laura hosts a podcast called Rescued By A Dog, which features stories of dogs saving their people. In this episode, Laura and I discuss: How we met and our long covid experiences Moving out of state in an attempt to see any improvement in our symptoms Acknowledging the privilege we both had to be able to move Low dose Naltrexone, Paxlovid, anesthesia, and ketamine therapy (none of this is medical advice!) What we call "zero dignity moments" with chronic illness EMDR, brain retraining, staying present "Resentment rebellion" Lymphatic massage The story behind Rescued by a Dog Find Rescued by a Dog on Spotify: https://open.spotify.com/show/0t6XikdERybsS3wwwaJb6j?si=c1654161e4504d1e And Apple Podcasts: https://podcasts.apple.com/us/podcast/rescued-by-a-dog/id1648960693 Support the podcast via Laura's Patreon: https://www.patreon.com/RescuedbyaDogPodcast Don't forget to like, subscribe, follow, and share A Friend for the Long Haul if you can. And if you're feeling extra generous, leave a review. Your support helps get this in front of more earballs and helps me bring more episodes. You can listen to the A Friend for the Long Haul Long Covid Theme Songs playlist on Spotify: https://open.spotify.com/playlist/3n0GXLFRWqDJyifglNNM4K?si=7948dbf2222c4392 If you'd like to support this low budget/high love podcast, you can check out my Bonfire shirt for silly long covid apparel where I'm raising money for a pro license of Zoom (as of right now, I can only record 30-40 minutes at a time and then we have to hang up and come back. Not great for conversational flow!): https://www.bonfire.com/store/a-friend-for-the-long-haul/ or my Amazon wishlist: https://www.amazon.com/hz/wishlist/ls/3MYBB5G0P7YUD?ref_=wl_share Thanks again for listening!
Some of you haven't listened to the amazing conversation I had with Yvans Jourdain and you need to!!!! We absolutely loved talking about all things spiritual, acting, overcoming insecurities and the journey life takes you on! PS - He's in a Paxlovid commercial and I just LOVE seeing Parks people out in the wild.
Comprehensive insights into Long COVID, Chronic Fatigue, and Recovery Strategies with Dr. Jacob Teitelbaum, a leading expert in chronic fatigue syndrome (CFS) and fibromyalgia. He's author of “You Can Heal From Long Covid: A Clinically Proven Program to Regain Your Health.” Dr. Teitelbaum details the intricacies of long COVID. The discussion encompasses similarities between long COVID and CFS, highlighting actionable treatments and addressing research gaps. Topics include neuroregeneration, viral reactivation, adrenal support, and the significance of the hypothalamus. Practical solutions are presented for optimizing vagal tone and mitochondrial energy, utilizing non-steroid adrenal support, and employing techniques like yoga and neurostimulation. The use of supplements, such as vitamins, ribose, and CoQ10, and the potential of high-dose CoQ10 chewables and HRG80 red ginseng, are emphasized for energy enhancement. The conversation also covers treatments like Ivermectin and the roles of Metformin, Paxlovid, and alternative therapies. Preventive strategies, including lifestyle adjustments for immunity, are discussed, alongside the importance of sleep, positivity, and balanced approaches to recovery, underscored by Dr. Teitelbaum's holistic SHINE protocol. You can reach out to Dr. Teitelbaum directly at FatigueDoc@gmail.com.
This episode of Going anti-Viral features an IAS–USA Dialogue titled "Latest Update on Urgent Viral Outbreaks," a panel discussion held on October 4, 2024. Dr Carlos del Rio from Emory University serves as moderator and welcomes 3 distinguished panelists: Dr Yvonne Maldonado from Stanford University, Dr Peter Chin-Hong from the University of California San Francisco, and Dr Paul Sax from Brigham and Women's Hospital. The episode covers various pressing topics, including updates on COVID-19, avian flu, mpox, and other viral diseases. Discussions touch on vaccines, their effectiveness, public health approaches, and current research.0:00 – Introduction and overview of ongoing viral outbreaks3:59 – Update on respiratory viruses and vaccination – seasonal flu, RSV, and COVID-1912:17 – Discussion of monoclonal antibody treatment for COVID-1914:15 – Update on the use of Paxlovid for COVID-1918:48 – COVID-19 vaccination – protein vaccines vs. mRNA vaccines22:48 – Update on pertussis28:54 – Discussion of seasonal influenza and vaccination32:55 – Effectiveness of shingles and RSV vaccines 35:57 – Discussion of vaccination during pregnancy40:02 – Audience questions43:04 – Update on H5N1 (avian flu) outbreak52:00 – Update on Marburg virus outbreak in Rwanda55:43 – Discussion of mpox outbreak in central Africa59:29 – Concluding remarks__________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...
Understanding Medicare Part D and the Inflation Reduction Act Kathe Kline is joined by Andrew Saul, Sales Director at Physicians Mutual, to delve into the complexities surrounding Medicare Part D and the changes ushered in by the Inflation Reduction Act. Key points of discussion included the new $2,000 out-of-pocket cap and its impact on seniors, along with price negotiation for prescription drugs. One of the major hurdles discussed was the inability of Medicare to negotiate drug prices, which has historically driven up costs for seniors. Andrew Saul illustrated this disparity with the example of Eliquis, a popular blood thinner. Non-Medicare recipients might pay $10 a month, while those on Medicare face costs upwards of $500 monthly without manufacturer coupons. Kathe shared her firsthand experience with prescription costs during her recent COVID-19 quarantine. The difficulty in navigating prescriptions, particularly the high cost and obstacles to obtaining Paxlovid, highlighted a larger issue within the system. She emphasized the restrictions Medicare beneficiaries face with manufacturer coupons, which can drastically reduce prescription costs for others. Andrew and Kathe explored the balancing act between allowing pharmaceutical companies to profit while ensuring fair drug pricing. Even with laws like the Insulin Savers Act capping prices, the lack of generic options keeps costs high. Andrew noted that new regulations will enable Medicare to negotiate prices for 10 high-cost drugs starting in 2026, but the scale of change is limited. The Inflation Reduction Act, passed in August 2022, is poised to bring changes such as Medicare's newfound ability to negotiate drug prices. Despite this advancement, critics argue for a more comprehensive and expedited implementation. Kathe contrasted the U.S. healthcare system with Europe's, noting Europe's more effective cost management due to direct government negotiations with drug manufacturers. Andrew offered insights into upcoming changes and the importance of well-informed agents in guiding clients through Medicare's intricacies. He emphasized that periodic drug plan reviews are crucial for cost savings. As we await further changes prompted by the Inflation Reduction Act, staying informed and proactive remains essential for Medicare beneficiaries and advisors alike. This episode is sponsored by CertifiedMedicareAgents.com
Health Affairs' Jeff Byers welcomes Brad Ryan, MD, Chief Growth Officer at NCQA, to the program to discuss the evolving state of EHRs, who owns the data, whether providers are excited about data standards, and what opportunities could be out there as health care embraces more digital efforts and arrangements.Health Affairs released an ahead-of-print article this week by Gillian K. SteelFisher and coauthors examining the public awareness and perceptions of Paxlovid as well as discovering that a majority of Americans have limited awareness of the at-home COVID-19 treatment. Order the September 2024 issue of Health Affairs.Related Articles:Digital Quality Transition Hub from NCQAElectronic health records giant Epic Systems sued over alleged monopolistic practices (Stat+)
In this episode, Dr. Osterholm and Chris Dall cover the latest infectious disease news on topics including H5N1, mpox, measles, and polio. Dr. Osterholm also answers an ID query on updated COVID-19 vaccines and gives his thoughts on a controversial study on Paxlovid. Evidence growing for COVID antivirals to cut poor outcomes, long COVID, experts say (CIDRAP News) The world is not ready for the next pandemic (Michael Osterholm & Mark Olshaker, Foreign Affairs) Interim clinical considerations for use of COVID-19 vaccines in the United States (CDC) Sign up for CIDRAP's daily newsletter MORE EPISODES SUPPORT THIS PODCAST
TALK TO ME, TEXT ITDespite extensive travel and countless interactions, one of us managed to avoid COVID-19 until now. Join us as we recount the initial symptoms, the reasoning behind choosing antibiotics over Paxlovid due to a history of respiratory issues, and the surprisingly delightful experience of watching "Doctor Strange" during the recovery phase. Our reflections on this journey through the pandemic blend personal anecdotes with light-hearted moments, making this episode both relatable and engaging.We then pivot to an intriguing discussion on the Marvel Universe, with a spotlight on Doctor Strange's rapid rise to power and role in the Avengers. This naturally leads us into a thought-provoking political commentary on Robert F. Kennedy Jr.'s critique of the Democratic Party and his choice of Nicole Shanahan as a running mate. We dissect media coverage discrepancies, debunk the myth of egg contamination, and speculate on potential political roles for RFK Jr. in a Trump administration. Wrapping up, we explore Governor Newsom's possible career shift from politics to media, all the while keeping the conversation lively and informative. Tune in for a compelling mix of health, entertainment, and political insights. Exit bumper Not A Democracy Podcast Network made by @FuryanEnergySupport the Show.Tip Jar for coffee $ - Thanks Blog - Carol ReMarksX - Carol ReMarks Instagram - Carol.ReMarksFacebook Page - Carol ReMarks Blog
In his weekly clinical update, Dr. Griffin discusses the harms of perpetuating the lab leak hypothesis and the recent ACIP recommendations for the RSV vaccine for those individuals over 60, before reviewing the recent statistics on SARS-CoV-2 infection, treatment guidelines for the different phases of COVID, including vaccines, Pemgarda, early treatment with Paxlovid, remdesivir and molnupiravir, steroids at the right time, anticoagulation support, immune modulation in some cases, and a comprehensive definition of long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Measles transmission after secondary vaccination failure (Emerg Inf Dis) Mpox public health emergency of international concern (WHO) First case of new mpox strain outside of Africa (Reuters) COVID-19 national trend (CDC) COVID-19 deaths (CDC) Where to get pemgarda (Pemgarda CDC Quarantine guidelines (CDC) Early phase of SARs-CoV-2 infection (COVID.gov) Individual monoclonal antibodies against SARS-CoV-2 should be used (CID) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID science, research and policy (Nature Medicine) Measurements of prior SARS-CoV-2 infection and postacute sequelae by the clinical laboratory (Annals of Internal Medicine) Risk factors for long COVID syndrome in postmenopausal women with previous SARS-CoV-2 infections (Annals of Epidemiology) New studies estimate long-COVID rates, identify risk factors (CIDRAP) Monitoring long COVID via telemedicine (PLoS One) Letters read on TWiV 1140 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
Jackie Johnson is here and she's ready to sacrifice her favorite onion rings for the greater good. Lizzy is also here and she's never been to Walmart. Daniel prefers curled chips and I'm confusing Daniel and Tony again. Is it because I have covid? We also talk about brain teasers, boundaries, snakes, Paxlovid, Japan, mushrooms and more. Plus we do a round of Just Me Or Everyone and Podcast Pals Product Picks. Get yourself some new ARIYNBF merch here: https://alison-rosen-shop.fourthwall.com/ Subscribe to my Substack: http://alisonrosen.substack.com Products I Use/Recommend/Love: http://amazon.com/shop/alisonrosen Check us out on Patreon: http://patreon.com/alisonrosen Buy Alison's Fifth Anniversary Edition Book (with new material): Tropical Attire Encouraged (and Other Phrases That Scare Me) https://amzn.to/2JuOqcd You probably need to buy the HGFY ringtone! https://www.alisonrosen.com/store/ Try Amazon Prime Free 30 Day Trial
In his weekly clinical update, Dr. Griffin discusses the harms of perpetuating the lab leak hypothesis and the recent ACIP recommendations for the RSV vaccine for those individuals over 60, before reviewing the recent statistics on SARS-CoV-2 infection, treatment guidelines for the different phases of COVID, including vaccines, Pemgarda, early treatment with Paxlovid, remdesivir and molnupiravir, steroids at the right time, anticoagulation support, immune modulation in some cases, and a comprehensive definition of long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Harms of the lab leak hypothesis (Journal of Virology) Lab leak mania (PaulOffit, Substack) This is a special message: pandemic started in nature! (TWiV) RSV vaccine recommendations August 6 2024 (MMWR) COVID-19 national trend (CDC) COVID-19 deaths (CDC) Where to get Pemgarda (Pemgarda) CDC Quarantine guidelines (CDC) Early phase of SARs-CoV-2 infection (COVID.gov) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID defined (NEJM) Contribute to our Floating Doctors fundraiser Lenacapavir on Puscast #60 Letters read on TWiV 1138 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
El Inegi dio a conocer que el Indicador Trimestral del PIB Turístico reportó un incremento 2.4% respecto al periodo inmediato anterior Por los efectos de la tormenta tropical Carlotta se reportaron interrupciones parciales o totales en varios tramos carreterosUna jueza federal en El Paso, Texas, califica el proceso contra El Mayo Zambada como “complejo e inusual”Más información en nuestro podcast
TWiV reviews whats going on with measles and its global resurgence, poliovirus found in Gaza, vaccine hesitancy in a community, 14 year old dies of Nipah, selection of SARS-CoV-2 viruses resistant to nirmatrelvir, and protective but non-neutralizing antibodies from survivors of Crimean-Congo hemorrhagic fever virus. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server What's going on with measles? (J Virol) Poliovirus in Gaza (Science) Sanitation concerns in Gaza (AP) Community vaccine beliefs (PLoS One) 14 year old dies of Nipah in India (Hindustan Times) Selection of nirmatrelvir resistance mutants (Sci Adv) CCHFV monoclonal antibodies (Cell Rep) CCHFV vaccine (TWiV 565) Prometheus Project (TWiV 578) TWiV at USAMRIID (TWiV 1015) Letters read on TWiV 1135 Timestamps by Jolene. Thanks! Weekly Picks Angela – Animal research is not always king Brianne – Why the US has more tornadoes than any other country Dickson – Earth's core has slowed so much it's moving backward Alan – Article about the Smithsonian's forensic ornithology lab, led by Carla Dove Vincent – Seventh patient ‘cured' of HIV: why scientists are excited Listener Pick Charles – An Inquiry into Morals by Robert M. Pirsig and My Beloved Monster by Caleb Carr Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Stories discussed this week:Ark. Supreme Court orders secretary of state to count some abortion petition signatureshttps://arktimes.com/arkansas-blog/2024/07/23/ark-supreme-court-orders-secretary-of-state-to-count-some-abortion-petition-signaturesState Supreme Court won't dismiss abortion petitioners' lawsuit, for nowhttps://arktimes.com/arkansas-blog/2024/07/26/state-supreme-court-wont-dismiss-abortion-petitioners-lawsuit-sets-briefing-scheduleDisgraced cult leader's name to be removed from Riverfront Park arthttps://arktimes.com/arkansas-blog/2024/07/25/disgraced-cult-leaders-name-to-be-removed-from-riverfront-park-artArkansas AG investigating another business with possible Chinese tieshttps://arktimes.com/arkansas-blog/2024/07/24/arkansas-ag-investigating-another-business-with-possible-chinese-tiesState does about-face on Chinahttps://www.arkansasbusiness.com/article/state-does-about-face-on-china/Pharmacies running low on Paxlovid as summer COVID spike continueshttps://arktimes.com/arkansas-blog/2024/07/26/pharmacies-running-low-on-paxlovid-as-summer-covid-spike-continuesWe welcome your feedback. Write us at podcasts@arktimes.com
In "Class is Not Dismissed," Dr. Osterholm and Chris Dall review the latest trends in COVID-19 and discuss new human cases of H5N1 influenza. Dr. Osterholm also answers an ID Query on Paxlovid eligibility and shares his perspective on timing the next dose of COVID-19 vaccine. Risk of long COVID has ebbed during pandemic, mostly thanks to vaccines, new data reveal (CIDRAP News) How a hotel convention became ground zero for this deadly bacteria (PBS News) Sign up for CIDRAP's daily newsletter MORE EPISODES SUPPORT THIS PODCAST
The gut link to autism: When Andrew Wakefield first proposed the connection in the 1990s, he was vilified, but new research supports microbiome impact on childhood neurodevelopment; President Biden is taking Paxlovid for COVID—will it help? When a “routine” X-ray leads to a wild goose chase; Astaxanthin shows promise for fatigue, muscle strength, cognition and aging; Introducing Mitopure®️, a urolithin A supplement, for mitochondrial support.
The Rich Zeoli Show- Full Episode (07/18/2024): 3:05pm- Biden Receptive to Withdrawing? The New York Times reportS, “President Biden has become more receptive in the last several days to hearing arguments about why he should drop his re-election bid, Democrats briefed on his conversations said on Wednesday, after his party's two top leaders in Congress privately told him they were deeply concerned about his prospects. Mr. Biden has not given any indication that he is changing his mind about staying in the race, the Democrats said, but has been willing to listen to rundowns of new and worrying polling data and has asked questions about how Vice President Kamala Harris could win.” 3:30pm Elizabeth Pipko—Spokeswoman for the Republican National Committee—joins The Rich Zeoli Show from The Republican National Convention to preview Donald Trump's convention speech, Hulk Hogan's highly anticipated appearance, and her neighbor: Kieth Olbermann! Pipko is a former model, a 2016 Trump campaign staffer, and author of the book, “Finding My Place: Making My Parents' American Dream Come True.” 3:40pm- Biden Has COVID-19: Tarini Parti and Kayla Yup of The Wall Street Journal write: “President Biden has tested positive for Covid-19, White House press secretary Karine Jean-Pierre said in a statement Wednesday. Biden, 81 years old, will be returning to Delaware to self-isolate, Jean-Pierre said. He tested positive for Covid-19 during a two-day campaign swing through the battleground state of Nevada. A note from Biden's doctor provided by the White House said the president's ‘symptoms remain mild, his respiratory rate is normal at 16, his temperature is normal at 97.8 and his pulse oximetry is normal at 97%.' Biden has received his first dose of Paxlovid and the results of a PCR test are pending, according to the note. He previously had Covid in the summer of 2022.” You can read the full article here: https://www.wsj.com/us-news/biden-tests-positive-for-covid-19-da64c5b8?mod=hp_lead_pos2 3:50pm- In a bizarre rant, MSNBC host Joy Reid suggested Joe Biden “beating” COVID-19 is the same as Donald Trump surviving an assassination attempt—arguing that both should be viewed by the public as signs of strength. 4:05pm- On Wednesday night, U.S. Senator J.D. Vance formally accepted the nomination to become Donald Trump's Vice Presidential nominee. During his speech Vance said: “Never in my wildest imagination would I have believed that I could be standing here tonight.” Vance had the thousands in attendance roaring while recalling stories from his youth—specifically stories about his grandma, “Mamaw.” Vance was introduced to the convention by his wife, Usha. 4:20pm- On Saturday, while speaking at a campaign rally in Butler, Pennsylvania former President Donald Trump survived an assassination attempt. Shooter Thomas Matthew Cooks—armed with an AR-15 rifle—fired multiple shots at Trump before being dispatched by a Secret Service sniper. Disturbing new details about the shooting continue to emerge. 4:30pm- While speaking with BET News, President Joe Biden seemingly thanked Franklin Delano Roosevelt for wide-spread access to high-speed internet. Of course, everyone remembers FDR's most famous quote: “The only thing we have to fear…is slow wi-fi.” 4:45pm- Gold Star Families: While speaking at the RNC Convention on Wednesday night, the parents of Marine Corps. Corporal Hunter Lopez remembered their son—as well as the other twelve U.S. military members killed during America's withdrawal from Afghanistan. 5:00pm Janiyah Thomas—Black Media Director for Donald Trump's 2024 Presidential Campaign—joins The Rich Zeoli Show from the RNC Convention in Milwaukee, Wisconsin to preview Donald Trump's big address tonight! 5:15pm- Coach Joe Kennedy joins The Rich Zeoli Show to discuss the new movie “Average Joe”—which tells the story of his fascinating life and legal fight. “School officials at Bremerton High School (BHS) suspended—and later fired—football coach Joe Kennedy because he prayed a brief, quiet prayer after football games. A lawsuit was filed against the school district, arguing that banning coaches from quietly praying, just because they can be seen by the public, is wrong and violates the Constitution. The U.S. District Court for the Western District of Washington, and then the U.S. Court of Appeals for the Ninth Circuit, sided with the school district. The case eventually landed in the U.S. Supreme Court. In January 2022, the Supreme Court agreed to hear the case. The Supreme Court has ruled in favor of Coach Joe.” You can learn more here: https://coachjoekennedy.com 5:35pm- Oklahoma Governor J. Kevin Stitt—Vice Chairman of the National Governors Association—joins The Rich Zeoli Show from the Republican National Convention in Milwaukee, Wisconsin and discusses recently signing “Alyssa's Law” which implements a mobile panic alert system in schools across the state. 5:40pm- Chairman of the Republican National Committee Michael Whatley joins The Rich Zeoli Show from the party's convention in Milwaukee, WI. How has the convention been so far—and what can Americans expect on Thursday night? 5:50pm- Former NBA player Enes Kanter Freedom joins The Rich Zeoli Show from the RNC Convention. In addition to playing professional basketball, Kanter Freedom is a human rights activist who has vociferously condemned totalitarian regimes. After publicly criticizing Recep Tayyip Erdogan, the Turkish president issued twelve arrest warrants for Kanter Freedom. 6:05pm- Biden Preparing to Withdraw from Race: Journalist Mark Halperin reports: “Multiple sources outline the apparent state of play on Biden at this time: plans to announce withdrawal from nomination as early as this weekend, with Sunday most likely. Jon Meacham polishing up remarks. Biden with NOT resign the presidency. Biden will NOT endorse Harris. open convention with Harris and about 3 others. super delegates will not be allowed to vote on 1st ballot. Harris is vetting at least four possible running mates, including Andy Beshear and possibly Shapiro.” You can follow the story as it develops: https://x.com/MarkHalperin/status/1814049842790006837 6:10pm- Michael D. Shear, Peter Baker, and Katie Rogers of The New York Times report: “Several people close to President Biden said on Thursday that they believe he has begun to accept the idea that he may not be able to win in November and may have to drop out of the race, bowing to the growing demands of many anxious members of his party. One of the people close to him warned that the president had not yet made up his mind to leave the race after three weeks of insisting that almost nothing would drive him out. But another said that ‘reality is setting in,' and that it would not be a surprise if Mr. Biden made an announcement soon endorsing Vice President Kamala Harris as his replacement.” You can read more here: https://www.nytimes.com/2024/07/18/us/politics/biden-election-drop-out.html 6:20pm- Congressman Dan Meuser— Representative for Pennsylvania's 9th Congressional District—joins The Rich Zeoli Show to recap his experience at last Saturday's presidential campaign rally in Butler, PA where former President Donald Trump was nearly assassinated. Rep. Meuser is a member of the U.S. House Committee on Financial Services and a member of the House Committee on Small Business. 6:40pm- David Urban—Political Commentator for CNN & Senior Advisor to Donald Trump—joins The Rich Zeoli Show from the RNC Convention in Milwaukee, WI. What can we expect from Republican presidential candidate Donald Trump's speech tonight? 6:50pm- Joel Pollak— Senior Editor-at-Large for Breitbart News—joins The Rich Zeoli Show to discuss his soon to be released book, “The Agenda: What Trump Should Do in His First 100 Days.” You can learn more about the book here: https://www.skyhorsepublishing.com/9781648211164/the-agenda/
The Rich Zeoli Show- Hour 1: 3:05pm- Biden Receptive to Withdrawing? The New York Times reportS, “President Biden has become more receptive in the last several days to hearing arguments about why he should drop his re-election bid, Democrats briefed on his conversations said on Wednesday, after his party's two top leaders in Congress privately told him they were deeply concerned about his prospects. Mr. Biden has not given any indication that he is changing his mind about staying in the race, the Democrats said, but has been willing to listen to rundowns of new and worrying polling data and has asked questions about how Vice President Kamala Harris could win.” 3:30pm Elizabeth Pipko—Spokeswoman for the Republican National Committee—joins The Rich Zeoli Show from The Republican National Convention to preview Donald Trump's convention speech, Hulk Hogan's highly anticipated appearance, and her neighbor: Kieth Olbermann! Pipko is a former model, a 2016 Trump campaign staffer, and author of the book, “Finding My Place: Making My Parents' American Dream Come True.” 3:40pm- Biden Has COVID-19: Tarini Parti and Kayla Yup of The Wall Street Journal write: “President Biden has tested positive for Covid-19, White House press secretary Karine Jean-Pierre said in a statement Wednesday. Biden, 81 years old, will be returning to Delaware to self-isolate, Jean-Pierre said. He tested positive for Covid-19 during a two-day campaign swing through the battleground state of Nevada. A note from Biden's doctor provided by the White House said the president's ‘symptoms remain mild, his respiratory rate is normal at 16, his temperature is normal at 97.8 and his pulse oximetry is normal at 97%.' Biden has received his first dose of Paxlovid and the results of a PCR test are pending, according to the note. He previously had Covid in the summer of 2022.” You can read the full article here: https://www.wsj.com/us-news/biden-tests-positive-for-covid-19-da64c5b8?mod=hp_lead_pos2 3:50pm- In a bizarre rant, MSNBC host Joy Reid suggested Joe Biden “beating” COVID-19 is the same as Donald Trump surviving an assassination attempt—arguing that both should be viewed by the public as signs of strength.
This week's topics include nasal sprays and URIs, Paxlovid in prevention, endometriosis and ovarian cancer, and diabetes after COVID-19.
*5:00am: Girls Bathroom Is A Sisterhood *6:00am: Unique House Rules, Rich Thing You Do *7:00am: Shoes Off When Entering Home, Stolen From You *8:00am: Kicked Off The Team, Sophie Says: Apple TV Show Sunny, Gen Z Term You Had To Teach *9:00am: COVID Uptick and Paxlovid
Some of today's top stories17 News is your local election headquarters... It's the last day of the republican national convention in Milwaukee. Tonight, former president donald trump will take the stage to formally accept his party's nomination, just days after surviving an attempt on his life. Last night republicans welcomed Ohio senator J-D vance to the national stage... For his first speech as the nominee for vice-president NBC's Brie Jackson has more from Milwaukee.Meantime.. President Biden has tested positive for COVID-19. The president had been in Las Vegas for a campaign event when he got that positive test. The White House reporting Biden is vaccinated and boosted against the virus and he is experiencing mild symptoms. Doctors gave him his first dose of Paxlovid. And he is now headed back to his home in Delaware, where he will self-isolate and carry out his regular duties.All this comes after Southern California congressman Adam Schiff joined the list of democrats calling for Biden to drop out of the presidential race....following his disappointing debate performance last month. Schiff said in a statement yesterday that Biden has made the country better...but the nation is at--quote--"a crossroads" and he has concerns about whether the president can defeat former President Trump in November. Schiff says it's time for the president to pass the torch, but promised to support whoever his party nominates next month.
COVID is back! Actually, it never went away. It's always been around and mutating into what is called variants. We will discuss the latest variant and how to prevent and treat it in an Effective and Safe way and even cure it. We will discuss Paxlovid and other medications benefits and risks as well. Actually, the show is timeless because what we will discuss will be helpful not just now, but in the future for all COVID virus outbreaks.
COVID is back! Actually, it never went away. It's always been around and mutating into what is called variants. We will discuss the latest variant and how to prevent and treat it in an Effective and Safe way and even cure it. We will discuss Paxlovid and other medications benefits and risks as well. Actually, the show is timeless because what we will discuss will be helpful not just now, but in the future for all COVID virus outbreaks.
President Joe Biden has tested positive for COVID-19, the White House announced yesterday. He is experiencing mild symptoms, like a runny nose and a nonproductive cough. Biden is both vaccinated and boosted against the virus. After delivering a speech in Las Vegas, he will return to Delaware to self-isolate, continuing his duties remotely. White House Press Secretary Karine Jean-Pierre assured the media that the President will keep performing his full responsibilities, and Biden's doctors noted that his vitals were normal as he started the Paxlovid treatment. The diagnosis comes amid rising pressure from Democrats, some of whom are questioning his campaign for reelection. Despite his illness, Biden remains committed, he says, to his role, emphasizing his determination to serve. The White House has promised regular updates on his health. The development follows Biden's previous positive COVID-19 test in July 2022, adding to the political tension as the November elections approach. Learn more about your ad choices. Visit megaphone.fm/adchoices
The Rich Zeoli Show- Hour 4: 6:00pm- Brilyn Hollyhand—Chairman of the GOP Youth Advisory Council & Bestselling Author of One Generation Away—joins The Rich Zeoli Show from the RNC Convention to talk about his new book: “One Generation Away.” 6:20pm- Biden Has COVID-19: Tarini Parti and Kayla Yup of The Wall Street Journal write: “President Biden has tested positive for Covid-19, White House press secretary Karine Jean-Pierre said in a statement Wednesday. Biden, 81 years old, will be returning to Delaware to self-isolate, Jean-Pierre said. He tested positive for Covid-19 during a two-day campaign swing through the battleground state of Nevada. A note from Biden's doctor provided by the White House said the president's ‘symptoms remain mild, his respiratory rate is normal at 16, his temperature is normal at 97.8 and his pulse oximetry is normal at 97%.' Biden has received his first dose of Paxlovid and the results of a PCR test are pending, according to the note. He previously had Covid in the summer of 2022.” You can read the full article here: https://www.wsj.com/us-news/biden-tests-positive-for-covid-19-da64c5b8?mod=hp_lead_pos2 6:50pm- Dave McCormick— Republican Candidate for U.S. Senate in Pennsylvania & former Under Secretary of the Treasury for International Affairs during the George W. Bush Administration—joins The Rich Zeoli Show to recap his speech at the RNC. Plus, McCormick talks about his experience attending the Butler, PA campaign rally where former President Donald Trump was nearly assassinated. You can learn more about his campaign here: https://www.davemccormickpa.com
The Rich Zeoli Show- Full Episode (07/17/2024): 3:05pm-Secret Service Director Subpoenaed: Jan Wolfe of The Wall Street Journal reports “A Republican-led congressional committee has issued a subpoena to Secret Service Director Kimberly Cheatle, formally demanding that she testify publicly next week about the assassination attempt on former President Donald Trump. The subpoena, issued by House Oversight Committee Chairman James Comer (R., Ky.), seeks Cheatle's testimony at a congressional hearing scheduled for the morning of July 22. In a letter to Cheatle accompanying the subpoena, Comer said Americans aren't getting accountability and transparency from the Secret Service about security failures that allowed a gunman to fire shots at Trump during a rally on Saturday in Pennsylvania. Comer questioned Cheatle's ability to lead the agency.” You can read more here: https://www.wsj.com/livecoverage/trump-biden-rnc-election-2024/card/secret-service-director-summoned-to-testify-before-congress-uchOceQMYmTQJ1mdQtSL 3:20pm- While speaking at the Republican National Committee Convention on Tuesday night, Florida Governor Ron DeSantis stated: “America cannot afford four more years of a ‘Weekend at Bernie's' presidency.” 3:40pm- On Tuesday night, speaking at the RNC Convention, former South Carolina Governor Nikki Haley declared that “a strong president doesn't start wars—a strong president prevents wars.” Haley also said that Donald Trump has her “strong endorsement.” Will her call for unity be enough to satisfy her coalition of more “moderate” Republicans. 4:05pm- Elbridge Colby—Former Deputy Assistant Secretary of Defense for Strategy and Force Development in the Trump Administration—joins The Rich Zeoli Show from the RNC Convention. Today's convention theme is “Make America Strong Again”—after years of Joe Biden signaling weakness internationally, how will a future Trump Administration reverse course? 4:15pm- Caroline Sunshine—Deputy Director of Communications, Donald J. Trump for President—joins The Rich Zeoli Show from the RNC Convention in Milwaukee, WI. While discussing the many failures of Bidenomics and the inflated cost of fast food, Sunshine hilariously notes that Joe Biden might be a “few French fries short of a Happy Meal.” 4:50pm- Perry Stein and Devlin Barrett of The Washington Post write: “Special counsel Jack Smith formally filed notice on Wednesday that he will appeal a Florida judge's decision to dismiss Donald Trump's 40-count indictment for allegedly mishandling classified documents and obstructing government efforts to retrieve them. The appeal, laying out Smith's argument for why the case should not be dismissed, is expected to land in the coming weeks in the Court of Appeals for the 11th Circuit—an appeals court in Atlanta whose jurisdiction covers Florida.” You can read the full article here: https://www.washingtonpost.com/national-security/2024/07/17/jack-smith-cannon-trump-appeal/ 5:00pm- Madeline Brame—a national victim rights advocate who rose to national prominence for standing up to Manhattan District Attorney Alvin Bragg after the senseless murder of her war hero son—joins The Rich Zeoli Show from Milwaukee, Wisconsin. Many are saying she has delivered the most powerful speech of the entire RNC convention. Brame is Project 21 Ambassador for The National Center for Public Policy Research. You can learn more about the organization here: https://nationalcenter.org/ncppr/staff/madeline-brame/ 5:45pm- Congressman Guy Reschenthaler—U.S. Representative for Pennsylvania's 14th Congressional District & House Republican Chief Deputy Whip—joins The Rich Zeoli Show from the RNC Convention…and he brought waters! 6:00pm- Brilyn Hollyhand—Chairman of the GOP Youth Advisory Council & Bestselling Author of One Generation Away—joins The Rich Zeoli Show from the RNC Convention to talk about his new book: “One Generation Away.” 6:20pm- Biden Has COVID-19: Tarini Parti and Kayla Yup of The Wall Street Journal write: “President Biden has tested positive for Covid-19, White House press secretary Karine Jean-Pierre said in a statement Wednesday. Biden, 81 years old, will be returning to Delaware to self-isolate, Jean-Pierre said. He tested positive for Covid-19 during a two-day campaign swing through the battleground state of Nevada. A note from Biden's doctor provided by the White House said the president's ‘symptoms remain mild, his respiratory rate is normal at 16, his temperature is normal at 97.8 and his pulse oximetry is normal at 97%.' Biden has received his first dose of Paxlovid and the results of a PCR test are pending, according to the note. He previously had Covid in the summer of 2022.” You can read the full article here: https://www.wsj.com/us-news/biden-tests-positive-for-covid-19-da64c5b8?mod=hp_lead_pos2 6:50pm- Dave McCormick— Republican Candidate for U.S. Senate in Pennsylvania & former Under Secretary of the Treasury for International Affairs during the George W. Bush Administration—joins The Rich Zeoli Show to recap his speech at the RNC. Plus, McCormick talks about his experience attending the Butler, PA campaign rally where former President Donald Trump was nearly assassinated. You can learn more about his campaign here: https://www.davemccormickpa.com
Is your yard a toxic Superfund site? Sick chimpanzees instinctively seek out medicinal herbs when sick; Are allergy shots worth it? Paxlovid flops for COVID pneumonia; Fish oil for hip arthritis; The verdict on Splenda; Which is better for brain health—whey protein or resistance exercise, or both? Do we all need more fiber?
In his weekly clinical update, Dr. Griffin discusses expanded use of the RSV vaccine by GSK, how the youngest member of the MicrobeTV family was hospitalized with RSV, why we are seeing more RSV infections than before the pandemic and how administration of monoclonal antibody therapy does not prevent infection but disease, before reviewing the weekly US COVID update, how SARS-CoV-2 affects neurodevelopment of the fetus and probability of preeclampsia, if giving Paxlovid prevents long COVID, and FDA recommends switching from the XBB.1.5 variant to JN.1 for fall COVID-19 vaccine formulations. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Young “Immune” co-host with RSV (YouTube) RSV on Immune (MicrobeTV) More children hospitalized with RSV after pandemic than before (Pediatrics) France supports Nirsevimab for RSV (Influenza and other respiratory viruses) Protects against disease not infection Nirsevimab (CIDRAP) TWiV tells it likes it is: protects against disease NOT infection (TWiV 695) RSV vaccine access expanded 50-59 (CIDRAP) GSK RSV vaccine expanded use for high risk 50-year olds (GSK) COVID-19 deaths COVID-19 national trend Neurodevelopmental delay in children whose mothers exposed to SARS-CoV-2 (Scientific Reports) Preeclampsia associated with SARS-CoV-2 infection (Journal of Maternal-Fetal & Neonatal Medicine) Effectiveness of nirmatelvir/ritonavir in children and adolescents (Nat Comm) JN.1 for fall COVID-19 boosters (FDA) COVID-19 vaccine booster switch (CIDRAP) EUA for pemgarda (FDA) Infusion centers near you! (pemgarda.com) CDC quarantine guidelines (CDC) Early phase of SARS-CoV-2 infection (COVID.gov) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (IDSociety) Drug interaction checker (University of Liverpool) Molnupiravir safety and efficiacy (JMV) Convalescent plasma recommendations for immunocompromised (ID Society) Updated respiratory virus guidelines (CDC) What to do when your healthcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staff shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID evidence based review TWiV shout out (TWiV 1088) Nirmatrelvir-ritonavir prevents long COVID-19? (JAMA Medicine) Contribute to our Floating Doctors fundraiser Letters read on TWiV 1122 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
This week, Kate, Gary, Mark and Henry discuss 4 new studies that answer some important questions: Does acetaminophen in pregnancy and neurodevelopmental outcomes in offspring? Can AI accurately diagnose otitis media in children? Is nirmatrelvir-ritonavir (Paxlovid) still an effective treatment for outpatients with mild to moderate COVID? And finally, what are the benefits and harms of continuous glucose monitoring in patients with type 2 diabetes.
Rumble has been shut off in Russia. What are Youtube, Facebook, and Twitter doing for Russia to keep from meeting the same fate as Rumble? It continues to be common among the elites to control the flow of information. Now, it's Putin's turn, although it;s not his first time doing this. But there's also this about Youtube: a Canadian court has greenlit a decision to allow a class action lawsuit against Youtube. They are being sued for their reporting on the Covid flu and the hiding of information. In fact, people like Chris Como are speaking out about the lies about Covid. You know, the very lies they helped spread. At the same time, we are learning the CDC tried to cover up the death of two teens, leading Professor Angus Dalgleish to speak out. What does God's Word say? Psalm 37:12-1412 The wicked plot against the righteous and gnash their teeth at them;13 but the Lord laughs at the wicked, for he knows their day is coming.14 The wicked draw the sword and bend the bowto bring down the poor and needy, to slay those whose ways are upright.Episode 1,592 Links:Rumble Is Blocked in Russia After Refusing Censorship Requests, CEO Says; Rumble vs. Russia: The video platform is blocked for refusing censorship, raising questions about other tech giants' compliance.Canadian Court Greenlights Class Action Lawsuit Against YouTube's Covid Censorship; In a landmark decision, a Canadian court allows a class action lawsuit to proceed, challenging YouTube's censorship of pandemic-related content.CDC Scrambled to Cover Up Sudden Deaths of 2 Teens Shortly after Covid Shots, Emails ShowFormer CNN anchor Chris Cuomo admits he now takes Ivermectin *everyday* to treat his Covid vaccine injuryAndrew Bridgen, MP: “Ask Penny Mordaunt about the recent admission of AstraZeneca that its vaccine causes blood clots. Ask her about their withdrawal of said vaccine worldwide. Get called a “conspiracy theorist” to a chorus of ‘hear hears.' Just another day in the UK Parliament.The Government Is Now Admitting That The Increase In Heart Disease And Excess Deaths Are Due To COVID Vaccines. Doctor Thomas Levy: "Vaccines are causing heart injury in at least 2.8% of people who received the Covid injections"Professor Dagleish, "co discoverer of the CD4 receptor", says "WE MUST STOP NOW", due to overwhelming concerns related to mRNA technology. London Professor of Oncology, and principal of the Institute for Cancer Vaccines and Immunotherapy, Professor Angus Dalgleish talks with Senator Ron Johnson. He begins with Fauci. OBGYN Doctor Calls on Attorneys to Sue Institutions That Forced COVID Shots on Babies & Pregnant WomenPfizer to Sell Drugs Online to Consumers, Bypassing Doctors and Pharmacies; Pfizer is developing a direct-to-consumer platform to sell some of its drugs online, including Paxlovid, which costs $1,400 for a five-day dose, and a migraine nasal spray.Green Masks, Red Faces; California teens win $1 million after misjudged "blackface" accusation goes viral.Meet Metro North Karen. What would you do4Patriots https://4Patriots.com/Todd Stay connected when the power goes out and get free shipping on orders over $97. Bioptimizers https://bioptimizers.com/todd Use promo code TODD for 10% off your order. Sharpen your edge and reach your potential with Mushroom Breakthrough by Bioptimizers. Bonefrog https://bonefrogcoffee.com/todd Use code TODD at checkout to receive 10% off your first purchase and 15% on subscriptions. Bulwark Capital Bulwark Capital Management (bulwarkcapitalmgmt.com) Call 866-779-RISK or visit online to get their FREE Common Cents Investing Guide. EdenPURE https://edenpuredeals.com Use code TODD3 to save $200 on the Thunderstorm Air Purifier 3-pack. GreenHaven Interactive Digital Marketing https://greenhaveninteractive.com Your Worldclass Website Will Get Found on Google! Native Path Krill https://nativepathkrill.com/todd For a limited time get Native Path Antarctic Krill Oil for as little as $23 per bottle. Renue Healthcare https://renuewellcation.com Register today for your Wellcation with Todd Herm
Nurses Out Loud - We explore the challenges and ethical concerns surrounding Paxlovid's use in pregnant women, examining its classification and safety data. We delve into the impact of COVID-19 on coagulation, discuss the financial motives in pharmaceutical promotions, and reflect on global drug policies. Additionally, we review films that contrast themes of leadership and societal challenges.
In "H5N1 Uncertainty," Dr. Osterholm and Chris Dall discuss the latest national COVID trends, a recent study on Paxlovid, and cases of H5N1 in cattle. Dr. Osterholm also shares the latest "This Week in Public Health History" segment and interviews two members of the podcast team.Please fill out our Listener Feedback Survey!Swedish study suggests link between long COVID and severity of illness (Stephanie Soucheray, CIDRAP News)Study: long COVID affects 8% of those with COVID-19, is more common in women (Stephanie Soucheray, CIDRAP News)New neurologic issues less likely after severe COVID than flu, research suggests (Mary Van Beusekom, CIDRAP News)Nirmatrelvir for vaccinated or unvaccinated adult outpatients with COVID-19 (Hammond et al., New England Journal of Medicine)Treating acute COVID-19 — final chapters still unwritten (Gandhi & Hirsch, New England Journal of Medicine)More episodesSupport this podcast
In "A Family Discussion," Dr. Osterholm and Chris Dall discuss the latest SARS-CoV-2 variant, consider the current and future challenges accessing Paxlovid, and explore new long COVID research. Dr. Osterholm also revisits last episode's discussion on changing public health guidelines and celebrates some canine heroes in the "This Week in Public Health History" segment. Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes (Yue Zhang, PNAS)Minnesota hospitals say 65,000 days of care were avoidable if patients had somewhere to go (Jeremy Olson, Star Tribune)Have a Paxlovid Prescription? Low Cost Options Available (Minnesota Department of Health)Find COVID-19 Medications (Administration for Strategic Preparedness and Response, HHS)Homeless man leaves puppies at N.C. shelter with heart-tugging note (Cathy Free, Washington Post)
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