Podcasts about Flair

  • 1,730PODCASTS
  • 3,894EPISODES
  • 1h 5mAVG DURATION
  • 5WEEKLY NEW EPISODES
  • Mar 23, 2023LATEST

POPULARITY

20152016201720182019202020212022

Categories



Best podcasts about Flair

Show all podcasts related to flair

Latest podcast episodes about Flair

WRESTLING SOUP
ITS BEGINNING TO LOOK A LOT LIKE WRESTLEMANIA (Wrestling Soup 3/22/23)

WRESTLING SOUP

Play Episode Listen Later Mar 23, 2023 53:41


- Ripley does the Crasher on the WWE 2k23 trailer- Buy WWE2K23 for less than anywhere else - Bringing CM Punk back to AEW? - A blood feud worth remembering - Goldberg AEW bound? dot dot dot - NIA Jax AEW bound? and why Kev thinks its a good idea - Appreciating the kind of character Ripley has become - Alexa Bliss beats skin cancer - Chad Gable and Otis direction - Holding out hope for the New Varsity Club - DSotR making a Scott Hall episode - Flair gets embarrassed by Dutch Mantell Support Wrestling Soup on Patreon:https://www.patreon.com/wrestlingsoupSOCIAL CHANNELS ʕ̡̢̡ʘ̅͟͜͡ʘ̲̅ʔ̢̡̢Twitter: https://twitter.com/WrestlingSoupInstagram: https://www.instagram.com/wrestlingsoup/Facebook: https://www.facebook.com/WrestlingSoup/Discord Channel: https://discord.gg/wrestlingsoup:shirt: PRO WRESLTING TEES STORE :shirt: /(=✪ x ✪=)\https://www.prowrestlingtees.com/wrestlingsoup

What Happened When
Episode 324: Dusty Goes Wild

What Happened When

Play Episode Listen Later Mar 22, 2023 140:51


On this episode of What Happened When, Tony's back and ready to deliver the laughs we've been missing! He and Conrad just back in the way back machine and take us to 1988 for historic episode of World Championship Wrestling. On this show you'll experience what both guys believe is JJ Dillion's best promo ever, Flair brings a Penthouse Pet to the studio, and Tully confronts Magnum TA causing Dusty to go bananas swinging a baseball bat and hitting Jim Crockett Jr! This is an episode you can't miss! NOTE: To watch along with the guys, head to Peacock season 4 episode 13 of World Class Wrestling HENSON - It's time to say no to subscriptions and yes to a razor that'll last you a lifetime. Visit HENSONSHAVING.com/WHW to pick the razor for you and use code WHW and you'll get two years' worth of blades free with your razor–just make sure to add them to your cart. ATHLETIC GREENS - To make it easy, Athletic Greens is going to give you a FREE 1 year supply of immune-supporting Vitamin D & 5 FREE travel packs with your 1st purchase. All you have to do is visit athleticgreens.com/WHW to take ownership over your health and pick up the ulimate daily nutritional insurance! BLUECHEW - Try BlueChew FREE when you use our promo code WHW at checkout--just pay $5 shipping. That's BlueChew.com, promo code WHW to receive your first month FREE SAVE WITH CONRAD - Stop throwing your money on rent! Get into a house with NO MONEY DOWN and roughly the same monthly payment at SaveWithConrad.com ADVERTISE WITH WHW - If your business targets 25-54 year old men, there's no better place to advertise than right here with us on What Happened When. You've heard us do ads for some of the same companies for years...why? Because it works! And with our super targeted audience, there's very little waste. Go to AdvertiseWithWHW.com now and find out more about advertising with What Happened When. Get all of your What Happened When merchandise at https://boxofgimmicks.com/collections/whwmonday BEST WAY TO SUPPORT THE SHOW - SUBSCRIBE, LIKE, WATCH and COMMENT on our YouTube channel! www.WHWOnYouTube.com FOLLOW ALL OF OUR SOCIAL MEDIA at https://whwmonday.com/ Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! Get all of your What Happened When merchandise at https://boxofgimmicks.com/collections/whwmonday Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Pope's Point of View
Pope's Point of View Episode 174

The Pope's Point of View

Play Episode Listen Later Mar 18, 2023 71:25


Ep. 174: Pope and Pollo discuss the on going beef between Ric Flair and Dutch Mantell, Muta entering the WWE HOF, Cody Rhodes RAW Promo, Taya Valkyrie's AEW Debut, NWA Powerrr and more.

Out of Character with Ryan Satin
SmackDown Roundup: Kevin Owens and Sami Zayn reunite

Out of Character with Ryan Satin

Play Episode Listen Later Mar 18, 2023 38:44


Ryan Satin recaps the 3/17/23 edition of Friday Night SmackDown, featuring: KO and Sami squashing their beef A brawl between Flair and Ripley Liv Morgan teaming with Raquel Rodriguez Drew McIntyre vs. Sheamus And more! Learn more about your ad choices. Visit megaphone.fm/adchoices

Ric Flair Wooooo Nation Uncensored
Who Ruined The NWA?

Ric Flair Wooooo Nation Uncensored

Play Episode Listen Later Mar 15, 2023 72:19


On this episode of To Be The Man, 16x World Heavyweight Champion Ric Flair and host Conrad Thompson discuss this week in Ric's Wild World. The guys share their thoughts on the NCAA Tournament, Aaron Rogers and where he could be playing next season, Ric's involvement in this years WWE Hall of Fame, and so much more! Plus, Ric answers several Twitter questions that reveal who he believes ruined the National Wrestling Alliance! Special thanks to this week's sponsors! Henson Shaving- It's time to say no to subscriptions and yes to a razor that'll last you a lifetime. Visit HENSONSHAVING.com/FLAIR to pick the razor for you and use code FLAIR and you'll get two years' worth of blades free with your razor–just make sure to add them to your cart. WoooooWings- WoooooWings- Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world championship wings by ordering with your Uber Eats or Postmates app. Wooooo! Wings now has more than 50 locations in 17 states - for a full list visit ricflairwings.com   FOLLOW AND SUBSCRIBE TO ALL THINGS RIC at https://linktr.ee/tobethemanpod Stop throwing your money on rent! Get into a house with NO MONEY DOWN and roughly the same monthly payment at SaveWithConrad.com Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! If your business targets 25-54 year old men, there's no better place to advertise than right here with us on To Be the Man with Ric Flair. You've heard us do ads for some of the same companies for years...why? Because it works! And with our super targeted audience, there's very little waste. Go to AdvertiseWithFlair.com now and find out more about advertising with To Be the Man with Ric Flair. Get all of your To Be the Man merchandise at RicFlairShop.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Patty-G Show
Episode #159 - Rubber Air With Lots of Flair - Animated Art Baton Rouge Balloon Decor

The Patty-G Show

Play Episode Listen Later Mar 15, 2023 63:50


Tabitha Miller left her career in Instrumentation to follow her passion for spreading joy to those in her community through face painting and balloon decor! In the beginning, she performed at restaurants and events, showcasing her art in the medium of face painting. With the emergence of Covid, her face painting took an abrupt halt; however, the pandemic did bring a silver lining. Many people at the time celebrated birthdays and anniversaries with roadside celebrations accompanied by big, beautiful balloons! From there, her love for the art of balloon decor took off, even leading her to compete on Team USA at the World Balloon Convention in Atlanta, GA. Since then, she has been creating extravagant, over-the-top balloon decor that demands to be the center of attention with its bright colors and unique configurations. In this episode, Tabitha talks about the decision to leave her career in STEM for one in the Arts, the lesser-known Rubber Tree, and her wildest design which includes a 12-foot moose. Thank y'all again for another great week! Please continue to share us with your friends, family, and colleagues so we can continue showcasing the amazing entrepreneurs that make up Baton Rouge. Don't forget to follow us on all of our socials, and we'll catch everyone back here next week! Sponsors: Fayala Real Estate, Gov't Taco, Horizon Financial Group, Mercedes-Benz of Baton Rouge, & Lake Men's Health Clinic Patty-G Wardrobe by: McLavy LTD. The Patty-G Show Website: https://thepattygshow.com Animated Art Baton Rouge Balloon Decor's Website: https://www.animatedart.us/ --- Send in a voice message: https://anchor.fm/thepattygshow/message Support this podcast: https://anchor.fm/thepattygshow/support

Scott and Kat After 9
Banks Failing and Airplanes Being Repossessed

Scott and Kat After 9

Play Episode Listen Later Mar 13, 2023 41:46


On today's After 9: A major bank in Silicon Valley has failed, Flair has a few planes grounded this weekend, Kat has to buy new appliances, and today's Missed Connections. Learn more about your ad choices. Visit megaphone.fm/adchoices

Solomonster Sounds Off
Sound Off 799 - WWE TRYING TO LEGALIZE BETTING ON MATCHES + ANOTHER AEW SHOW?

Solomonster Sounds Off

Play Episode Listen Later Mar 12, 2023 117:54 Very Popular


Support our sponsor by using the link below for the special Solomonster offer!RAYCON - Get 15 PERCENT OFF your Raycon order when you visit http://buyraycon.com/solomonster and use the code SOLOMONSTER at checkout!Solomonster remembers Mae Young on what would have been her 100th birthday and then has a TON of news with thoughts on WWE trying to legalize betting on matches in certain states and why it could be a disaster... Backlash coming to Puerto Rico with Bad Bunny and ANOTHER major show being planned outside the mainland US... Vince McMahon and his creepy new mustache backstage at Raw, why he was supposedly there and why that's not the whole story, plus a funny Zelina Vega story on pitching anime to McMahon... John Cena TORCHES Austin Theory on Raw and why it all but gave away the finish of their match at Wrestlemania... Rey Mysterio announced for the WWE Hall of Fame, the legend who will be inducting him and Hulk Hogan teases an old school TAG TEAM going in this year?... Triple H already working to PACK AND STACK the card for WrestleMania 40... AEW reportedly getting MORE television from Warner Brothers Discovery and the rumored day of the week the new show will be airing... the sad state of Wardlow in AEW, the social media drama between QT Marshall and Raj Giri with QT clapping back at criticism of Wardlow's booking... GCW holding up the release of the AEW Fight Forever game?... Brian Cage testing out free agency soon... Mark Briscoe announces plans to crown NEW Ring of Honor tag team champions... MLW amends its lawsuit against WWE and why it alleges its new TV deal with Reelz is in grave danger... Ric Flair wins SAD TWEET for his response to Dutch Mantell's comments about Flair's retirement match last year... NXT ROADBLOCK thoughts, including how to debut Dragon Lee at Stand & Deliver, Johnny Gargano returning to wrestle Grayson Waller and Shawn Michaels replicating his OWN ANGLE with Roxanne Perez... the NXT star LEAVING the company and what led to their downfall... and YOUR QUESTIONS on Tony Khan giving creative input to his wrestlers, the best Undertaker streak matches that never get talked about and lots more!***Follow Solomonster on Twitter for news and opinion:http://www.twitter.com/solomonsterSubscribe to the Solomonster Sounds Off on YouTube:https://www.youtube.com/user/TheSolomonster?sub_confirmation=1Become a Solomonster Sounds Off Channel Member:https://www.youtube.com/channel/UC9jcg7mk93fGNqWPMfl_Aig/join

The Pope's Point of View
Pope's Point of View Episode 173: "Pollo's Point of View"

The Pope's Point of View

Play Episode Listen Later Mar 11, 2023 72:11


Ep. 173: Pope and Pollo switch roles as Pollo captains the ship as we talk AEW Revolution and cover all things In Da Newz.

Ric Flair Wooooo Nation Uncensored
MJF throws Tequila on a child

Ric Flair Wooooo Nation Uncensored

Play Episode Listen Later Mar 8, 2023 75:56 Very Popular


This week on To Be The Man, Ric Flair and Conrad Thompson talk about A LOT of topics. Including "Tequila Gate" but also VKM's Mustache, Hockey, and MORE Special thanks to this week's sponsors! Henson- It's time to say no to subscriptions and yes to a razor that'll last you a lifetime. Visit HENSONSHAVING.com/FLAIR to pick the razor for you and use code FLAIR and you'll get two years' worth of blades free with your razor–just make sure to add them to your cart. WoooooWings- Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world championship wings by ordering with your Uber Eats or Postmates app. Wooo Wings is now open in Nashville, San Antonio, Jacksonville, Florida as well as Huntsville and Tuscaloosa in Alabama, with many more locations coming soon. Try the only chicken wings worthy of carrying the name of the 16x World Heavyweight Champion. FOLLOW AND SUBSCRIBE TO ALL THINGS RIC at https://linktr.ee/tobethemanpod Stop throwing your money on rent! Get into a house with NO MONEY DOWN and roughly the same monthly payment at SaveWithConrad.com Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! If your business targets 25-54 year old men, there's no better place to advertise than right here with us on To Be the Man with Ric Flair. You've heard us do ads for some of the same companies for years...why? Because it works! And with our super targeted audience, there's very little waste. Go to AdvertiseWithFlair.com now and find out more about advertising with To Be the Man with Ric Flair. Get all of your To Be the Man merchandise at RicFlairShop.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Heel Truth
Is Friedman the next Flair? Ep210

The Heel Truth

Play Episode Listen Later Mar 7, 2023 39:36


This week I discuss is MJF the next Ric Flair. Artwork- @fudjins Host-Ted Hill the Hillbilly Heel heeltruthpodcast@gmail.com Please click on the links and check out our friends. Welcome to the Shiz Show https://open.spotify.com/episode/5Wid6fcc73TUCngyelf5hN?si=rvAhkN_QSiahSdoumkDg7w Jaded Wrasslin https://open.spotify.com/episode/4Ge4ODMMGVjixyoyGepY99?si=V7yaQ7O7SPawrF8qc2fzGg All F'N Wrestling https://www.youtube.com/live/Uk6LKWuJPCQ?feature=share --- Support this podcast: https://anchor.fm/ted-the-hillbilly-heel/support

The Pope's Point of View
Pope's Point of View Episode 172: Wrestling w/Reality

The Pope's Point of View

Play Episode Listen Later Mar 4, 2023 64:55


Ep. 172: Pope and Polo talk Wrestling w/Reality, Sonya Deville Arrested, Brock Lesnar says no to Bray Wyatt matchup at Wrestlemaina, The 2022 Wrestling Observer Awards and more.

Ric Flair Wooooo Nation Uncensored
WON Year End Awards

Ric Flair Wooooo Nation Uncensored

Play Episode Listen Later Mar 1, 2023 69:00


Get ready for a wild ride on this week's episode of To Be The Man! It's Ric's birthday week, and to celebrate, he's answering all of YOUR burning questions. But that's not all - the guys are diving into the latest buzz surrounding the WON Year-End Awards, the XFL's exciting comeback, and the infamous Jake Paul. With so much to unpack, you won't want to miss a minute of this jam-packed episode. So, buckle up and tune in for some riveting discussion with your favorite Hall of Famer podcaster! Special thanks to this week's sponsors! Titan Nutrition-- Enlite comes in 6 amazing flavors that can be easily mixed and taken on the go. Find it at TitanNutrition.net and save 10% plus get free shipping when you use code FLAIR at checkout. WoooooWings- Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world championship wings by ordering with your Uber Eats or Postmates app. Wooo Wings is now open in Nashville, San Antonio, Jacksonville, Florida as well as Huntsville and Tuscaloosa in Alabama, with many more locations coming soon. Try the only chicken wings worthy of carrying the name of the 16x World Heavyweight Champion. FOLLOW AND SUBSCRIBE TO ALL THINGS RIC at https://linktr.ee/tobethemanpod Stop throwing your money on rent! Get into a house with NO MONEY DOWN and roughly the same monthly payment at SaveWithConrad.com Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! If your business targets 25-54-year-old men, there's no better place to advertise than right here with us on To Be the Man with Ric Flair. You've heard us do ads for some of the same companies for years...why? Because it works! And with our super-targeted audience, there's very little waste. Go to AdvertiseWithFlair.com now and find out more about advertising with To Be the Man with Ric Flair. Learn more about your ad choices. Visit megaphone.fm/adchoices

Radio Cherry Bombe
Abi Balingit Of The Dusky Kitchen On Fashion, Flair, And Filipino Desserts

Radio Cherry Bombe

Play Episode Listen Later Feb 27, 2023 45:39


Hosted by Kerry DiamondProduced by Catherine Baker and Jenna SadhuEdited by Jenna SadhuRecorded at CityVox StudiosMusic by Tralala, “All Fired Up”As one of the most stylish New Yorkers around, Abi Balingit manages to bring flair and creativity to everything she does, even her baked goods. As the talent behind The Dusky Kitchen blog and IG account, she's known for her unique twist on Filipino treats, and now, those recipes and the stories behind them can be found in her debut cookbook, Mayumu: Filipino American Desserts Remixed.Abi joins host Kerry Diamond to talk about growing up in a tight-knit Filipino family, why she never thought she'd have a cookbook, her teenage crush on the Food Network, and the pasalubong boxes she creates to raise funds for causes close to her heart. Join Radio Cherry Bombe for a live event in Sacramento with California Grown on Wednesday, March 8th. Get your tickets here. For Jubilee tickets, click here. Radio Cherry Bombe is a production of The Cherry Bombe Podcast Network. Subscribe to our newsletter and check out past episodes and transcripts here. More on Abi: Instagram, The Dusky Kitchen blog, her debut cookbook Mayumu

The Pope's Point of View
Pope's Point of View Episode 171

The Pope's Point of View

Play Episode Listen Later Feb 25, 2023 52:25


Ep. 171: Pope and Pollo Del Mar return to discuss the passing for the great Jerry Jarrett and his impact on the world of wrestling as we know it today while also breaking down the latest WWE PLE and NWA PPV.

Fantasy Soccer FC Podcast
FPL 2022/23 - GW 24 - A Flair Up

Fantasy Soccer FC Podcast

Play Episode Listen Later Feb 23, 2023 93:31


Incoming double match week!!! We cover just about everything you need to know to be prepared. Don't enjoy, its crap.

Ric Flair Wooooo Nation Uncensored
WHAT is on Ric's Mind? II

Ric Flair Wooooo Nation Uncensored

Play Episode Listen Later Feb 23, 2023 71:56


Today on To Be The Man Ric and Conrad "shoot" on whatever comes to mind. Roman Reigns, Sami Zayn, Jake Paul, Ring of Honor...They are all fair game! Special thanks to this week's sponsors! Backyard Butcher- Visit BackyardButchers.com and use promo code FLAIR to get 15% off your order, free shipping, and 4 free ribeyes for life! WoooooWings- Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world-championship wings by ordering with your Uber Eats or Postmates app. Wooo Wings is now open in Nashville, San Antonio, Jacksonville, Florida as well as Huntsville and Tuscaloosa in Alabama, with many more locations coming soon. Try the only chicken wings worthy of carrying the name of the 16x World Heavyweight Champion. FOLLOW AND SUBSCRIBE TO ALL THINGS RIC at https://linktr.ee/tobethemanpod Stop throwing your money on rent! Get into a house with NO MONEY DOWN and roughly the same monthly payment at SaveWithConrad.com Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! If your business targets 25-54 year old men, there's no better place to advertise than right here with us on To Be the Man with Ric Flair. You've heard us do ads for some of the same companies for years...why? Because it works! And with our super targeted audience, there's very little waste. Go to AdvertiseWithFlair.com now and find out more about advertising with To Be the Man with Ric Flair. Get all of your To Be the Man merchandise at RicFlairShop.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Cultaholic
WCW Nitro #36: Slamboree 1996 Was POINTLESS! | CULTAHOLIC CLASSIC NITRO REVIEW

Cultaholic

Play Episode Listen Later Feb 23, 2023 81:40


WCW Nitro #36 | May 20th, 1996: The Giant puts the WCW World Heavyweight Championship on the line against Arn Anderson. "Macho Man" Randy Savage is on the hunt for Ric Flair as Flair goes one on one with Eddie Guerrero. Lex Luger & Sting take on The Faces of Fear in tag team action. The Steiner Brothers, Diamond Dallas Page, and many more are featured.Sam Driver and Tom Campbell travel back in their Slim Jim-Powered DeLoreon to watch every single episode of WCW Monday Nitro from the very beginning to the bitter end. Hosted on Acast. See acast.com/privacy for more information.

It's Mike Jones
Liv Morgan Talks Elimination Chamber, Smackdown, Path To WrestleMania and Chucky!

It's Mike Jones

Play Episode Listen Later Feb 23, 2023 11:01


Liv Morgan joins me to talk about her incredible night at Elimination Chamber, Smackdown coming back to DC on March 3rd at Capital One Arena, what her path to WrestleMania looks like, investing in the Sami Zayn / Bloodline story, Charlotte Flair, Wheel of Fortune and Chucky!

Attitude Era Wrestling Review

It's the fallout from Halloween Havoc! What will happen between the NWO and WCW tonight? Hogan issues an open challenge to anyone! Flair vs Macho Man! Four title matches! And it's a three hour Nitro? Did we mention that it's a three hour Nitro?Drew and Arnold are joined by Lauren from the "Beer'd Al Podcast" and Russ from the "Infectious Groove Podcast" to talk about this classic Monday Nitro!!!You can follow Lauren on Twitter @BeerdAlPodcastYou can follow Russ on Twitter @Infectious_PodAnd subscribe to their YouTube at Youtube.com/@InfectiousGroovePodcastIf you'd like to help support us through our Patreon page you can visit it at Patreon.com/AttitudeEraWrestlingReviewFollow us on Twitter and IG: @AEWRPodJoin our Patreon at Patreon.com/AttitudeEraWrestlingReview Jetfire - Jeff II https://youtu.be/ZbyFsGMjfRg Creative Commons Attribution Free Download / Stream: http://bit.ly/-jetfire Music promoted by Audio Library https://youtu.be/nrIxa0jbhwE AEWR logo art by Russ from @Infectious_Pod

Outlook
Becoming Blair 'the Flair': a boxer on the run, part 2

Outlook

Play Episode Listen Later Feb 20, 2023 32:42


In the ring, Blair finds calm amidst the chaos of his life. Back in the US Blair Cobbs falls again on hard times; homeless in Philadelphia his boxing dream seems out of reach. But a string of lucky breaks may just tip the balance. Blair's brazen alter-ego who's kept him alive thus far now has a name – Blair ‘the Flair' – and some recognition in the ring. But could ‘the Flair' take him all the way to the top of the boxing world? Presenter: Asya Fouks Producer: Louise Morris

Locked On Predators - Daily Podcast On The Nashville Predators
Tommy Novak, Ryan McDonagh Shine in Nashville Predators' "Raccoon in a Trash Can" Weekend Series

Locked On Predators - Daily Podcast On The Nashville Predators

Play Episode Listen Later Feb 20, 2023 39:45


The Nashville Predators split what turned out to be an exciting and eventful weekend doubleheader... a 7-3 blowout win over the Florida Panthers and a 4-3 heartbreaker to the Minnesota Wild that saw a Ryan Hartman "raccoon in a trash can" goal doom the Preds. And the Locked On Predators crew couldn't help but notice a couple of shiny bright spots, especially the play of young Tommy Novak (who should NOW go by "Thomas.") We break down his 5-point weekend and discuss why John Hynes deserves SOME credit for his performance. Also in this episode: -Why Ryan McDonagh's play this season reminds Nick of a certain Quentin Tarantino character. -Does the Preds' play this weekend change your expectations for what David Poile might do at the NHL Trade Deadline? -What can last week's embarrassing loss to the Boston Bruins teach the Predators about themselves? -Jeremy Lauzon's terrible, horrible, no-good, very bad week. -Nino Niederreiter comes through with some FLAIR against the Minnesota Wild. Follow & Subscribe on all Podcast platforms…

The Pope's Point of View
Pope's Point of View Episode 170: "The Perfect 10" Babydoll

The Pope's Point of View

Play Episode Listen Later Feb 18, 2023 50:51


Ep. 170: Pope sit's down for a one on one interview with the Legendary Nikla Roberts aka Babydoll to discuss her start in World Class Wrestilng, Jim Crockect Promotions, why she never went to WWE, Dusty Rhodes, The "Brown Envelope" and much more.

Ric Flair Wooooo Nation Uncensored
ASK RIC + Superbowl

Ric Flair Wooooo Nation Uncensored

Play Episode Listen Later Feb 15, 2023 69:59


On this episode of To Be The Man, Ric and Conrad talk about recent news in the wrestling world before Ric answers YOUR questions! Topics include the passing of Jerry Jarrett and Lanny Poffo, Elimination Chamber, the possibility of a new "Nature Boy," Ric's upcoming birthday plans, a Facetime with Tom Brady, and much more! Special thanks to this week's sponsors! Backyard Butcher- Visit BackyardButchers.com and use promo code FLAIR to get 15% off your order, free shipping, and 4 free ribeyes for life! HelloFresh- Go to HelloFresh.com/FLAIR65 and use code FLAIR65 for 65% off plus free shipping! WoooooWings- Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world-championship wings by ordering with your Uber Eats or Postmates app. Wooo Wings is now open in Nashville, San Antonio, and Jacksonville, Florida as well as Huntsville and Tuscaloosa in Alabama, with many more locations coming soon. Try the only chicken wings worthy of carrying the name of the 16x World Heavyweight Champion. FOLLOW AND SUBSCRIBE TO ALL THINGS RIC at https://linktr.ee/tobethemanpod Stop throwing your money on rent! Get into a house with NO MONEY DOWN and roughly the same monthly payment at SaveWithConrad.com Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! If your business targets 25-54-year-old men, there's no better place to advertise than right here with us on To Be the Man with Ric Flair. You've heard us do ads for some of the same companies for years...why? Because it works! And with our super-targeted audience, there's very little waste. Go to AdvertiseWithFlair.com now and find out more about advertising with To Be the Man with Ric Flair. Get all of your To Be the Man merchandise at RicFlairShop.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Outlook
Becoming Blair 'the Flair': a boxer on the run, part 1

Outlook

Play Episode Listen Later Feb 13, 2023 40:12


From Beverly Hills to hiding from the law with his dad, Blair's seen it all. To help him get through the tough times – and there'd be quite a few of those – Blair created a separate persona. This was the fearless alter ego he could rely on to swoop in and save the day. The Peter Pan to his Lost Boy. And Blair was certainly lost now - would he make it back out of Mexico alive? Clips: Clueless/ Amy Heckerling/ Paramount Pictures Presenter: Asya Fouks Producer: Louise Morris

Dirty Disco - Electronic Music Podcast
Dirty Disco 492 by Dragan Kucirov who takes over the music podcast with great flair and style!

Dirty Disco - Electronic Music Podcast

Play Episode Listen Later Feb 12, 2023 126:26


This week's episode of the Dirty Disco podcast is a special takeover by Dragan Kucirov! This respected DJ hailing from North Macedonia has put together an exclusive vinyl dj set that will have you dancing all night long. With mixes of house, deep and disco, Dragan is sure to get [...] The post Dirty Disco 492 by Dragan Kucirov who takes over the music podcast with great flair and style! appeared first on Dirty Disco - Curated Electronic Music & more.

ARN
Episode 181: The Last of the Real Men (July 1991)

ARN

Play Episode Listen Later Feb 11, 2023 81:01


On this episode of ARN, Arn and Paul continue their look back through 1991, as they revisit July of that year! Topics include...Flair vs. Herd as told by Jim Herd, Herd's opinion on the Midnight Express and Arn's reaction, the results of The Great American Bash, and much more! BLUE CHEW - www.BlueChew.com - promo code ARN to receive your first month FREE! JIMMY'S FAMOUS SEAFOOD - www.JimmysFamousSeafood.com ships nationwide. Free 2-day nationwide shipping on orders over $125 (excluding steamed crabs and fresh items) use the promo code: ARN WOOOOO WINGS - Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world championship wings by ordering with your Uber Eats or Postmates app. Wooooo Wings is now open in Nashville, San Antonio, Jacksonville, Florida as well as Huntsville and Tuscaloosa in Alabama, with many more locations coming soon. Try the only chicken wings worthy of carrying the name of the 16x World Heavyweight Champion. SAVE WITH CONRAD - If you have credit card debt or in a 30-year loan? Well, we can help you get out of that pinch and save money at the same time! Head over to SaveWithConrad.com for a quick quote. Arn can be found on ADFREESHOWS.com, the largest collection of wrestling legends on one channel. www.ADFREESHOWS.com will have every podcast ad free and early, plus bonus content you won't get anywhere else. Join today www.ADFREESHOWS.com Now you can enjoy ARN on YouTube! Turn on your notifications at http://www.ArnShowOnYouTube.com  If your business targets 25-54 year old men, there's no better place to advertise than right here with us on the Arn Show. You've heard us do ads for some of the same companies for years...why? Because it works! And with our super targeted audience, there's very little waste. Go to AdvertiseWithArn.com now and find out more about advertising with the Arn Show. Get all of your Arn Anderson merchandise at https://boxofgimmicks.com/collections/arn Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Pope's Point of View
Pope's Point of View Episode 169: "The Genuis" Lanny Poffo

The Pope's Point of View

Play Episode Listen Later Feb 11, 2023 59:41


Ep. 169: Pope and Pollo Del Mar talk the passing of "The Genuis" Lanny Poffo, Update on Jerry "The King" Lawler, Cody Rhodes/Paul Heyman Exchange, NWA Powerrr and a HUGE GUEST ANNOUNCEMENT for next week's PPV Edition and more.

Cultaholic
WCW Nitro #35 | The Giant DESTROYS Lex Luger | CULTAHOLIC CLASSIC WCW NITRO REVIEW

Cultaholic

Play Episode Listen Later Feb 9, 2023 85:14


WCW Nitro #35 | May 13th, 1996: On this episode of WCW Monday Nitro The Giant puts the WCW World Heavyweight Championship on the line against 'The Total Package' Lex Luger. 'Nature Boy' Ric Flair takes on V.K. Wallstreet. The Public Enemy face The Steiner Brothers in tag team action. The rivalry between Flair and 'Macho Man' Randy Savage reaches new levels. Sam Driver and Tom Campbell travel back in their Slim Jim-Powered DeLoreon to watch every single episode of WCW Monday Nitro from the very beginning to the bitter end. Hosted on Acast. See acast.com/privacy for more information.

Ric Flair Wooooo Nation Uncensored

This week on To Be the Man, Ric's internet is out so we are giving you some of his STIFFEST, MOST LIVE ROUNDS from ALL of his podcasts Special thanks to this week's sponsors! Backyard Butcher- Visit BackyardButchers.com and use promo code FLAIR to get 15% off your order, free shipping and 4 free ribeyes for life! Jimmy's Seafood- JimmysFamousSeafood.com free 2-day nationwide shipping on orders over $125 (excluding steamed crabs and fresh items) use the promo code: FLAIR WoooooWings- Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world championship wings by ordering with your Uber Eats or Postmates app. Wooo Wings is now open in Nashville, San Antonio, Jacksonville, Florida as well as Huntsville and Tuscaloosa in Alabama, with many more locations coming soon. Try the only chicken wings worthy of carrying the name of the 16x World Heavyweight Champion. FOLLOW AND SUBSCRIBE TO ALL THINGS RIC at https://linktr.ee/tobethemanpod Stop throwing your money on rent! Get into a house with NO MONEY DOWN and roughly the same monthly payment at SaveWithConrad.com Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! If your business targets 25-54 year old men, there's no better place to advertise than right here with us on To Be the Man with Ric Flair. You've heard us do ads for some of the same companies for years...why? Because it works! And with our super targeted audience, there's very little waste. Go to AdvertiseWithFlair.com now and find out more about advertising with To Be the Man with Ric Flair. Get all of your To Be the Man merchandise at RicFlairShop.com Learn more about your ad choices. Visit megaphone.fm/adchoices

The Pope's Point of View
Pope's Point of View Episode 168: Post Royal Rumble Edition

The Pope's Point of View

Play Episode Listen Later Feb 4, 2023 59:48


Ep. 168: Pope and Polo Del Mar return to discuss the results of the Royal Rumble, May Valentine Playboy Debut, NWA first ever live Powerrr, AEW Samoa Joe vs Darby All In and more.

Awesome Truth: A Wrestling Book Club
Is the Ric Flair Peacock Doc Worth a Watch?

Awesome Truth: A Wrestling Book Club

Play Episode Listen Later Feb 1, 2023 42:26


The Ric Flair story has been told up and down, left and right. We covered his autobiography on the very first episode of this show, we covered his 30 for 30 back in 2017, and his sexual transgressions were well-detailed in the Plane Ride From Hell episode of Dark Side of the Ring. But now, Peacock and WWE Network Documentaries have given us even more Nature Boy, as Woooooo! Becoming Ric Flair was released to the world in December 2022. Does the world really need another 2 hours of Flair chatter? Is there more of his life to dissect and analyze? Join us as we discuss Ric Flair yet again, hopefully for the last time.

Out of Character with Ryan Satin
WWE Raw Roundup: Royal Rumble Fallout

Out of Character with Ryan Satin

Play Episode Listen Later Jan 31, 2023 60:54


Ryan Satin recaps the 1/30/23 edition of Raw, featuring: Cody Rhodes calling out Roman Reigns Rhea Ripley challenging Flair at WM Elimination Chamber qualifiers Edge and Beth Phoenix The return of Rick Boogs And more! Plus, Ryan gives some of his delayed Royal Rumble thoughts. Learn more about your ad choices. Visit megaphone.fm/adchoices

Manchester Is Red
Man Utd 3-1 Reading | Antony & Casemiro's Brazilian Flair | Forest Semi-Final Preview

Manchester Is Red

Play Episode Listen Later Jan 30, 2023 46:54


George Smith is joined by Chief Manchester United writer Samuel Luckhurst and Senior Football writer Rich Fay to discuss United's FA Cup win over Reading, Antony's continued good form, Casemiro's brilliance, the players expected to leave on loan and a preview for the second leg Carabao Cup semi-final tie against Forest at Old Trafford. Learn more about your ad choices. Visit megaphone.fm/adchoices

The Pope's Point of View
Pope's Point of View Episode 167

The Pope's Point of View

Play Episode Listen Later Jan 28, 2023 63:43


Ep. 167: Pope and Polo return to discuss the success of RAW 30, Ric Flair makes amends backstage, AEW Dynamite Jay Briscoe Tribute, Mark Briscoe vs Jay Lethal, Royal Rumble predictions and more!

Shaunie in the Wrasslin
The Return of RAWQ: Random Ass Wrasslin Questions

Shaunie in the Wrasslin

Play Episode Listen Later Jan 25, 2023 99:32


Questions, Trivia, Rick Steiner, Whose The bigger star, yay or Nay, Rick Steiner, big shows career, Flair in the attitude era, RICK STEINER!!!! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Ric Flair Wooooo Nation Uncensored

This week on To Be The Man, Ric Flair talks about his time coming back to the WWE for RAW is XXX and his all of the goings on backstage. Special thanks to this week's sponsors! Backyard Butcher- Visit BackyardButchers.com and use promo code FLAIR to get 15% off your order, free shipping and 4 free ribeyes for life! WoooooWings- Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world championship wings by ordering with your Uber Eats or Postmates app. Wooo Wings is now open in Nashville, San Antonio, Jacksonville, Florida as well as Huntsville and Tuscaloosa in Alabama, with many more locations coming soon. Try the only chicken wings worthy of carrying the name of the 16x World Heavyweight Champion. FOLLOW AND SUBSCRIBE TO ALL THINGS RIC at https://linktr.ee/tobethemanpod Stop throwing your money on rent! Get into a house with NO MONEY DOWN and roughly the same monthly payment at SaveWithConrad.com Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! Get all of your To Be the Man merchandise at RicFlairShop.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Rugby on Off The Ball
Munster played with French flair in Toulouse | Fergus McFadden post-match reaction

Rugby on Off The Ball

Play Episode Listen Later Jan 22, 2023 10:42


Fergus McFadden joins Dave McIntyre after Munster earn a bonus point against Toulouse in France. McFadden touches on Munster's exciting future, the impact of the new coaching staff and Joey Carbery's response to being dropped by Ireland. With Vodafone Ireland #TeamOfUs

PWTorch Dailycast
PWTorch Dailycast – PWTorch ‘90s Pastcast - Moynahan & McDonald discuss issue #209 (1-11-93) of the PWTorch including Flair returning to WCW

PWTorch Dailycast

Play Episode Listen Later Jan 21, 2023 147:08


Patrick Moynahan and Alex McDonald kick off the fifty-third episode of PWTorch ‘90s Pastcast discussing issue #209 of the PWTorch including news of Ric Flair returning to WCW, when his WWF tenure ends, and all of the booking possibilities. They also discuss some WWF news, Wade's Torch Talk with British Bulldog, some more Rumble trivia, and so much more. Email us questions or comments at torchpastcast@gmail.com.

Something to Wrestle with Bruce Prichard
Episode 371: Royal Rumble - The 90s Recap!

Something to Wrestle with Bruce Prichard

Play Episode Listen Later Jan 20, 2023 171:12


On this episode of Something To Wrestle with Bruce Prichard, host Conrad Thompson walks us through some great moment from previous Royal Rumble episodes covering the 1990s! Hogan, Flair, Austin, Michaels and even the chairman of the board are all covered on this packed look back at the Royal Rumble in the 1990s. SLEEPME - Head over to sleep.me/WRESTLE to learn more and save 25% off the purchase of any new Dock Pro, Cube, or OOLER Sleep System. This offer is available exclusively for What Happened When listeners -- and only for a limited time! BLUECHEW - Try BlueChew FREE when you use our promo code WRESTLE at checkout--just pay $5 shipping. That's BlueChew.com, promo code WRESTLE to receive your first month FREE ATHLETIC GREENS - To make it easy, Athletic Greens is going to give you a FREE 1 year supply of immune-supporting Vitamin D & 5 FREE travel packs with your 1st purchase. All you have to do is visit athleticgreens.com/WRESTLE to take ownership over your health and pick up the ultimate daily nutritional insurance! CAMPERMAXX - Camper Maxx. Specializing in MAXX discounted pricing on Travel Trailers and Fifthwheel RV's delivered anywhere in the lower 48! Visit: campermaxx.com or call 256-320-7033 JIMMY'S FAMOUS SEAFOOD - JimmysFamousSeafood.com ships nationwide. Free 2-day nationwide shipping on orders over $125 (excluding steamed crabs and fresh items) use the promo code: WRESTLE SAVE WITH CONRAD - Don't put the new years bills on a credit card! Go to savewithconrad.com and let us help you put some cash back in your pockets! WOOOOO WINGS - Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world championship wings by ordering with your Uber Eats or Postmates app.  Wooo Wings is now open in Nashville, San Antonio, Jacksonville, Florida as well as Huntsville and Tuscaloosa in Alabama, with many more locations coming soon.  Try the only chicken wings worthy of carrying the name of the 16x World Heavyweight Champion. FOLLOW ALL OF OUR SOCIAL MEDIA at https://stwlinks.com/ Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! Learn more about your ad choices. Visit podcastchoices.com/adchoices

Straight Shooters
351: RIP Jay Briscoe; WWE Royal Rumble 2017 Deep Dive

Straight Shooters

Play Episode Listen Later Jan 20, 2023 180:28


We sure will "Remember the Rumble" from 2017 in the Alamodome for... being one of the most boring Rumbles of all time. What's not boring is our takes on it, so press that play button as we dive deep into the 2017 WWE Royal Rumble. Cena ties Flair! Jericho in a shark cage! More! But first, we start off on a somber note and pay tribute to one of the most influential professional wrestlers of all time, Jamin Pugh, better known as Jay Briscoe. -- Follow us on Twitter [@_piccone] [@VaughnMJohnson] [@theshooterspod] You can subscribe to The Straight Shooters on the following platforms: [Apple Podcasts] [Google Podcasts] [Spotify] [iHeartRadio] [Amazon] [Audacy] [TuneIn Radio] [Pandora] [Stitcher] [Spreaker] [Player FM] and wherever else you get your podcasts! Exclusive Patreon content: [patreon.com/theshooterspod] Facebook: [The Straight Shooters] E-mail: [straightshooterspodcast@gmail.com] --- Send in a voice message: https://anchor.fm/theshooterspod/message Support this podcast: https://anchor.fm/theshooterspod/support

Stroke Alert
Stroke Alert January 2023

Stroke Alert

Play Episode Listen Later Jan 19, 2023 44:57


On Episode 24 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the January 2023 issue of Stroke: “Covert Brain Infarction as a Risk Factor for Stroke Recurrence in Patients With Atrial Fibrillation” and “Subarachnoid Hemorrhage During Pregnancy and Puerperium.” She also interviews Dr. Georgios Tsivgoulis about his article “Clinical, Neuroimaging, and Genetic Markers in Cerebral Amyloid Angiopathy-Related Inflammation: A Systematic Review and Meta-Analysis.” Dr. Negar Asdaghi:         Let's start with some questions. 1) When during pregnancy is an intracranial aneurysm at the highest risk of rupture? 2) What does the presence of covert brain infarcts mean in the setting of atrial fibrillation? 3) And, finally, how is the inflammatory form of cerebral amyloid angiopathy different from the classic CAA form, and why is it important to differentiate between the two? We'll be answering these questions and much more in today's podcast. We're covering the latest in cerebrovascular disorders, and this is the best in Stroke. Stay with us. Welcome back to another issue of the Stroke Alert Podcast. My name is Negar Asdaghi. I'm an Associate Professor of Neurology at the University of Miami Miller School of Medicine and your host for the monthly Stroke Alert Podcast. Together with my co-editors, Drs. Nastajjia Krementz and Eric Goldstein, here's our article selection for the month of January. Symptomatic intracerebral hemorrhage is a feared complication of reperfusion therapies in acute stroke, so there's a lot of interest in looking for predictors of development of this complication, especially when you're making decisions for pursuing endovascular therapy. For many years now, we've known about some of these predictors, such as presence of a large infarct core and high blood glucose levels. But in the recent years, other radiographic markers of tissue viability, such as a poor collateral status and unfavorable venous outflow profile, have been shown to be predictors of post-reperfusion hemorrhagic transformation. In this issue of the journal, we learn about another imaging marker that can potentially predict parenchymal hemorrhage occurrence post-endovascular therapy, which is high hypoperfusion intensity ratio, or HIR, as measured by perfusion imaging. What is HIR? It's a long name for a simple ratio that can easily be measured by dividing the volume of tissue with Tmax delay of over 10 seconds to the volume of tissue with Tmax delays of over 6 seconds. Simply put, Tmax 10 divided by Tmax 6. These volumes, as you know, are typically provided to us by almost all post-processing perfusion softwares, and so this ratio can be easily calculated in the acute setting. So, in this paper led by Dr. Tobias Faizy from University Medical Center in Hamburg and colleagues, we learned that higher hypoperfusion intensity ratios are strongly associated with parenchymal hemorrhage occurrence after endovascular therapy. So, in summary, HIR, that is a quantitative ratio, can be used as a marker to risk stratify patients that are undergoing endovascular therapy in terms of helping us predicting the risk of development of intracerebral hemorrhage after reperfusion therapies. In a separate study in this issue of the journal, we read a very interesting paper titled "Anti-Epileptic Drug Target Perturbation and Intracranial Aneurysm Risk." How are intracranial aneurysms even related to anti-epileptic drugs? Well, first of all, it's been known for a long time based on genome-wide association studies that there are multiple common genes that are associated with increased risk of intracranial aneurysm development. Now, some of the largest genetic studies to date have shown pleiotropy between genetic causes of development of intracranial aneurysms and genes encoding targets for anti-epileptic drugs. Now that's a fascinating finding because finding commonalities between these genes may help find new treatment targets for intracranial aneurysms. So, in this paper in this issue of the journal, the investigators from the University Medical Center in Utrecht found an association in the expression of anti-epileptic drug target gene CNNM2 and intracranial aneurysm risk. They found that certain anti-epileptic drugs, such as phenytoin, valproic acid, and carbamazepine, that are expected to lower CNNM2 levels in the blood may subsequently lead to a lower risk of development of intracranial aneurysms. And, of course, a reasonable follow-up study to this would be to investigate whether persons exposed to these anti-epileptic drugs have indeed a lower risk of unruptured intracranial aneurysms and subarachnoid hemorrhage, and how variation in CNNM2 expression can lead to development of aneurysms. Bottom line, CNNM2 may be a relevant drug target for treatment of cerebral aneurysms. As always, I encourage you to review these papers in detail in addition to listening to our podcast today. My guest on the podcast today is the Chairman of Neurology at the University of Athens, Dr. Georgios Tsivgoulis. He joins me all the way from Greece to talk about cerebral amyloid angiopathy-related inflammation, or CAA-ri. He's a remarkable researcher, and I can say with absolute confidence that we cannot find a better summary of this very tough topic elsewhere. He ends the interview with an intriguing account of the early description of dementia in Greek mythology. But first, with these two articles. What are covert brain infarcts, or CBIs? Are these the John Wick or the James Bond of the stroke world? After all, they operate undercover. They're ominous and attack without warning. That's probably why they're also called silent infarcts. Now, whatever we call them, we need to know how prevalent they are and what does their presence actually mean. Let's dive into this topic. For at least two centuries, if not longer, we've known about covert brain infarcts. Early description of these lesions is credited to Amédée Dechambre, a medical intern at Salpêtrière Hospital in Paris who noted that there are strokes that can cause symptoms like hemiplegia, but also strokes that are asymptomatic, or so he thought at the time. In the modern times, while we agree with our pathology forefathers that CBIs are different from symptomatic strokes, we also know that they are not entirely asymptomatic. The symptoms can be subtle and tend to sneak up on the patient, but what is clear is that amassing of covert brain infarcts results in an overall decline in cerebrovascular reserve of the brain. With the advent of neuroimaging, we now know that CBIs are age-dependent and prevalent, seen in almost 10 to 30% of even healthy adults, but much more prevalent in those with vascular risk factors, and they can be caused by nearly the entire spectrum of neurovascular disease, including large vessel, small vessel disorders, cardioembolism, and others. Now, how do these covert infarcts catch up in those with atrial fibrillation? Neuroimaging studies have shown that patients with A-fib, especially those untreated, have a higher percentage of embolic-appearing CBIs, and conversely, those with embolic formed pattern of CBIs are more likely to have undiagnosed A-fib. So the question is, what's the significance of CBI in those with confirmed A-fib? In this issue of the journal, Dr. Do Yeon Kim from Seoul National University and colleagues help us answer this question using the EAST-AF, which stands for East Asian Ischemic Stroke Patients With Atrial Fibrillation Study. So, the paper included over 1300 patients with A-fib and first-ever stroke without a prior history of TIA or stroke. And then they categorized these patients into those who had evidence of CBI on neuroimaging and those who didn't. So, what did they find? Forty-two percent of patients with A-fib and first-ever stroke had evidence of covert brain infarcts on neuroimaging. Let's think about it for a moment. These patients presented with what was thought to be their first-ever stroke, not knowing they already had some in their brain. Now, what makes things really worse is that over a quarter of these subjects had more than just one covert infarct. Not surprisingly, those with CBI tended to be older, had higher blood pressure, and had worse white matter hyperintensity burden. This is kind of expected and also not expected was the fact that most of these covert infarcts were actually embolic in pattern. Over 60% of them were embolic. Another 14% of cases had combined embolic and non-embolic-appearing CBIs. Now, overall, the one-year incidence of ischemic stroke and all-cause mortality was higher in those that had CBIs at baseline. When they started looking at the specific patterns of CBIs, those embolic-appearing CBIs had a threefold higher risk of recurrent ischemic stroke, whereas those with non-embolic-appearing covert infarcts had oddly a higher all-cause mortality rate but not recurrent ischemic stroke. And finally, just briefly, the authors noted that the addition of CBIs to the classic CHA2DS2-VASc score didn't meaningfully otherwise statistically improve the scoring metrics, so they left it at that. So, the take-home message is that 42% of A-fib patients presenting with first-ever stroke actually had prior strokes without even knowing based on this study. And most of these strokes were embolic-appearing, and these covert brain infarcts can be used as predictors of future clinical strokes in this population. Strokes should be the last thing to worry about when we think of pregnancy. In the United States, around 30 in 100,000 women, unfortunately, experienced a stroke during pregnancy, and between 6 to 8 in 100,000 deliveries are complicated by subarachnoid hemorrhage. What's the most common cause of pregnancy-associated subarachnoid hemorrhage? In the general population, close to 80% of subarachnoid hemorrhage cases are aneurysmal. Is this true for the pregnant population as well? And importantly, what's the contemporary incidence trend, risk factors, and outcomes of pregnancy-related subarachnoid hemorrhage? In this issue of the journal, Dr. Korhonen and Petra [Ijäs] and their colleagues from the Departments of Neurology and Obstetrics and Gynecology at Helsinki University Hospital will give us the answers to some of these questions through a nationwide population-based study in Finland. So, they looked at over one and a half million pregnant women who gave birth during a 30-year time period between 1987 to 2016. Subarachnoid hemorrhage was identified through appropriate ICD codes and then further adjudicated based on confirmatory information, including neuroimaging and data from lumbar puncture. A total of 57 cases of pregnancy-related subarachnoid hemorrhage was identified in this paper. The mean age of women was 33, ranging from 23 to 45, and the clinical presentation was typical for subarachnoid hemorrhage, including thunderclap headache and mild neurological symptoms. So, what did they find? So, first off, in terms of general observations, the overall incidence rate of pregnancy-related subarachnoid hemorrhage in this study was 3 over 100,000 deliveries. This is almost half the incidence rate reported from the nationwide registries in the United States. Seventy-seven percent of pregnancy-related subarachnoid hemorrhage cases were aneurysmal, so very similar to the general population. The other 23% were non-aneurysmal cases, but it's important to note that 40% of those non-aneurysmal cases also had vascular etiologies, so etiologies such as moyamoya syndrome, postpartum angiopathy, AVM, to name a few. Like non-pregnant patients with subarachnoid hemorrhage, the aneurysmal cases were sicker patients in general. They had a lower GCS at presentation, higher Hunt and Hess scores, and required more ICU admissions. The next finding is very important because it actually shows that development of subarachnoid hemorrhage during pregnancy significantly impacted obstetrical care. A total of 66% of women with subarachnoid hemorrhage during pregnancy ended up having a C-section and a high percentage of these cesarean sections were actually elective. This is in contrast with subarachnoid hemorrhages in the postpartum period where 67% of women had spontaneous vaginal deliveries. The other important finding of the paper was really highlighting the differences between pregnancy-related aneurysmal versus non-aneurysmal subarachnoid hemorrhages. We already talked about how, in general, aneurysmal cases had more severe neurological presentations, so, not surprisingly, they also had worse outcomes with a mortality rate of 16% for the aneurysmal subarachnoid hemorrhage cases, and only 68% of women with pregnancy-related aneurysmal subarachnoid hemorrhage reached a favorable outcome, which was defined in this study as modified Rankin Scale of 0 to 2. Other important differences included the fact that the incidence of aneurysmal subarachnoid hemorrhage increased towards the end of pregnancy and was highest in the third trimester. This ties in with the findings from prior studies all indicating that rupture of an aneurysm is most common in the third trimester. By contrast, the incidence of non-aneurysmal subarachnoid hemorrhage peaked in the second trimester in this study. And finally, in terms of risk factors, first let's talk about age. The incidence rate of pregnancy-associated subarachnoid hemorrhage increased with age of the mother. So, in this study, there were no cases noted amongst women aged below 20 years of age to an incident rate of 12 per 100,000 deliveries among women aged 40 years or over. So that's a fourfold increase from the overall incidence rate of pregnancy-related subarachnoid hemorrhage, and very important point that we learned from this paper. Apart from age, smoking beyond 12 weeks of gestation and hypertension were also independent factors associated with pregnancy-related subarachnoid hemorrhage. So, overall, hypertension, smoking are bad and are significant risk factors for pregnancy-related subarachnoid hemorrhage. And if we have to remember just one thing from this paper, let it be this one: The rupture of an aneurysm is most common in the third trimester of pregnancy. Cerebral amyloid angiopathy, or CAA, is an important cause of intracranial hemorrhage and refers to deposition of β-amyloid fibrils in the wall of the small- and medium-sized cerebral blood vessels, mostly involving cortical and leptomeningeal arteries. It is believed that the deposition of β-amyloid results in architectural disruption of the blood vessels, which then leads to perivascular leakage. That's the pathophysiological mechanism behind the development of cerebral microbleeds. And this process, of course, can cause frank vascular rupture resulting in cortical intracerebral hemorrhage or development of high-convexity subarachnoid hemorrhages. It is important to note that varying amounts of perivascular inflammation, that is inflammation surrounding β-amyloid-laden blood vessels, may be present in some CAA cases, rendering them the designation of inflammation-related CAA. However, frank vasculitic destruction of the vessel wall, such as what is found in amyloid-β-related angiitis, or ABRA, and primary angiitis of the central nervous system, is usually absent in most CAA-related inflammation cases. How these entities are best defined, diagnosed, and treated is subject of intense research. In this issue of the journal, in the study titled "Clinical, Neuroimaging, and Genetic Markers in CAA-Related Inflammation," Dr. Georgios Tsivgoulis and colleagues take us through a systematic review and meta-analysis of published studies of patients with CAA-related inflammation. I am joined today by Dr. Tsivgoulis himself to discuss this paper. He's a Professor of Neurology and Chairman of the Second Department of Neurology at the University of Athens School of Medicine. Dr. Tsivgoulis is the residency program director and the director of cerebrovascular fellowship program with extensive research and expertise in the field of stroke. Good morning, Georgios, and welcome to our podcast. Dr. Georgios Tsivgoulis: Good morning, Negar. I'm delighted to be here and delighted to present our findings, on behalf of all our co-authors. Dr. Negar Asdaghi:         Thank you very much for being here and congrats again on the paper. So, Georgios, let's start with this interest that's going on with using clinical and radiographic features to make the diagnosis of CAA-related inflammation in contrast to moving ahead and performing brain biopsy. Can you please start us off with a brief review of the newly proposed clinico-radiographic criteria for this condition, please? Dr. Georgios Tsivgoulis: Yes. As you mentioned, Negar, CAA-ri is a distinct, however, rare subset of cerebral amyloid angiopathy. Firstly, Greenberg and the Boston group published in Neurology in 2007 a paper highlighting that a diagnosis of a probable CAA-ri patient could be made on the basis of characteristic clinical and neuroimaging findings without requiring a biopsy. Following this observation, Chung and colleagues in 2010, in a seminal paper in JNNP, proposed the first diagnostic criteria for probable and definite CAA-ri. For the definite diagnosis, besides the typical clinical presentation with headache, encephalopathy, focal neurological signs and seizures, and the characteristic neuroimaging findings with T2 or FLAIR hyperintense asymmetric white matter lesions complicated with microbleeds and leptomeningeal or parenchymal gadolinium enhancement, and histopathological confirmation with amyloid deposition within cortical leptomeningeal vessels associated with perivascular, transmural or intramural inflammation was also required. The latest criteria developed in 2015 by Auriel and colleagues that were published in JAMA Neurology using a validation study modified the current criteria for the diagnosis of CAA-ri. In this paper, the author supported the use of empirical immunosuppressive therapy, avoiding brain biopsy, for patients meeting the criteria proposed for probable CAA-ri. They suggested that a brain biopsy should be considered in empirically treated patients who failed to respond to corticosteroid therapy within three weeks. The criteria by Auriel and colleagues are widely applicable in everyday clinical practice, and we also use this criteria for the inclusion of studies in our current meta-analysis. I would like to highlight for our audience that the latest criteria for CAA-ri were published in 2015 by Auriel and colleagues. However, these are different for the criteria for cerebral amyloid angiopathy than the latest criteria were published in 2022 in Lancet Neurology, OK? Dr. Negar Asdaghi:         Georgios, that was a great start for this interview. You had mentioned a lot of information here. I just want to highlight what you just said. So, we are using for this meta-analysis, the latest criteria in CAA-related inflammation published in JAMA by Auriel and colleagues. That's slightly different than, we're not referring to the 2022 criteria of cerebral amyloid angiopathy. It's an important distinction. We're going to talk about this a little more as we go through the interview, but I want to come back to your current paper and start from there. Can you please tell us about the importance of this paper, why doing a meta-analysis was important in your view, and tell us a little bit about the studies that were included in your paper? Dr. Georgios Tsivgoulis: Yes, thank you for that question. CAA-ri is an increasingly recognized entity since the recent diagnostic criteria by Auriel and colleagues published in 2015. In collaboration with the greater availability of the high-resolution MR, we can have now a reliable non-invasive diagnosis of possible or probable CAA-ri, avoiding the risk of brain biopsy. However, I need to highlight that the early diagnosis remains a great challenge for the clinicians and neurologists. Searching the literature, we observe that there is scarce data regarding the prevalence of the distinct clinical, neuroimaging, and genetic markers among patients diagnosed with CAA-ri. We believe that pooling all this information in the current meta-analysis would be very helpful for every clinician, increasing a comprehensive understanding of this rare cerebrovascular disorder. Consequently, we conducted this meta-analysis including 21 studies that recruited a total of 378 patients with CAA-ri. Our study involved only 4 prospective and 17 retrospective hospital-based cohorts of patients diagnosed with CAA-ri based on autopsy or biopsy or on the recent Auriel diagnostic criteria that do not require autopsy or biopsy. Due to limited data in the literature regarding this entity, we had to include only small cohort studies with at least five patients in our meta-analysis. We excluded case reports and case series with less than five patients. This is, by far, the largest available sample of CAA-ri patients in the literature. Dr. Negar Asdaghi:         OK, great. So, let me just recap this, more so for myself. So, we have 21 studies, and you excluded studies that included less than 5 patients. So, practically speaking, case reports. Dr. Georgios Tsivgoulis: Yes, and single-case reports. Dr. Negar Asdaghi:         Yes. And practically speaking, of the total number of patients that are included in this meta-analysis, you have 378 cases, and basically the diagnosis of CAA-related inflammation was either based on the newly proposed criteria or based on biopsy-confirmed or autopsy cases. Dr. Georgios Tsivgoulis: Which is the standard criteria. Dr. Negar Asdaghi:         So, now, I'm dying to ask you about these clinical and radiographic characteristics of patients with CAA-related inflammation in this meta-analysis. Dr. Georgios Tsivgoulis: The mean age of patients in the included studies was approximately 72 years old, and there was no obvious gender predominance. Fifty-two percent of the patients were of female sex. In our study, 70% of the included patients presented with cognitive decline, which was the most common neurological manifestation, while 50% of the total sample had focal neurological signs and 54% encephalopathy presentation. Symptoms such as headache and seizures were less common, 37 and 31% respectively. With regard to the radiological findings, hyperintense T2 FLAIR white matter lesions were very, very common in 98% of our patients, and they were also complicated with lobar cerebral microbleeds, with a prevalence of 96%, and these two were, by far, the most prevalent neuroimaging findings, that white matter hyperintensities coupled with a cerebral microbleed. The pooled prevalence rates of gadolinium-enhanced lesions was 54%, and also the prevalence of cortical superficial siderosis was 51%, which is also very high in this cohort of patients with CAA-ri. Dr. Negar Asdaghi:         OK. So many of the features Georgios said, you mentioned, from presence of white matter hyperintense lesions on T2 FLAIR to presence of cortical microbleeds or superficial siderosis, these features are also seen in patients with cerebral amyloid angiopathy. What are some of the important differentiating features between the two conditions? Dr. Georgios Tsivgoulis: Yes, this is an excellent clinical question. First of all, the lower age threshold for CAA-ri is 40 years old, whereas in cerebral amyloid angiopathy, the lower age threshold is 50 years. So, patients who are younger than 50 years can be diagnosed with CAA-ri, but they cannot be diagnosed with CAA. Another issue is that comparing the result of this meta-analysis with another recent meta-analysis focusing on CAA, on cerebral amyloid angiopathy, that our international multi-collaborative group published in Stroke in 2002, we also evaluated the presence of clinical phenotypes and radiological markers among patients with cerebral amyloid angiopathy. We have documented that transient focal neurological episodes are much more common in patients with cerebral amyloid angiopathy in contrast to patients with CAA-ri. These episodes, which are called TFNEs, transient focal neurological episodes, are attributed to cortical subarachnoid hemorrhage or cortical superficial siderosis. So, I think this is another important clinical distinction. The most important, however, differentiating features between the two entities are neuroimaging markers, in specific, in particular, T2 FLAIR hyperintense unifocal or multifocal lesions with mass effect. These are the most prevalent neuroimaging features among patients with CAA-ri, but they're very seldomly described in patients with cerebral amyloid angiopathy, in patients with CAA. Another characteristic neuroimaging finding very indicative of the inflammation is the leptomeningeal or parenchymal gadolinium enhancement. This finding has been very rarely described in patients with non-inflammatory cerebral amyloid angiopathy. So, the clinical distinction is not so solid. However, the neuroimaging distinction would provide us with very strong information that can help us differentiate these two conditions. Dr. Negar Asdaghi:         Excellent points, I have to say, golden points, not just excellent points. I'm going to try to recap this and see if I understood it correctly. So, for our listeners, we have two conditions that potentially have many common points. One is the cerebral amyloid angiopathy, and the second one, which is obviously the subject of this interview, is cerebral amyloid angiopathy-related inflammation. The most important differentiating factors between the two are actually the neuroimaging features, as Georgios mentioned. So, the first feature that was mentioned is presence of T2 FLAIR hyperintense lesions. Some of them are large and have actually mass effects. This feature is rarely seen in patients with CAA, and it's an important radiographic factor that is seen in patients with CAA-related inflammation. The second distinguishing feature was leptomeningeal enhancement, again, rarely seen in non-inflammatory CAA, but was seen in a significant proportion of patients with CAA-related inflammation. These were the neuroimaging features. You also mentioned two other factors. The median age of CAA-related inflammation was lower than CAA. That can be helpful. And also the entity of transient focal neurological episodes, or TFNE, is rarely seen in inflammatory cases of CAA, whereas it is described in cases with cerebral amyloid angiopathy and mostly related to development of either cortical subarachnoid hemorrhage or cortical superficial siderosis. I think I got this all, correct? Dr. Georgios Tsivgoulis: Excellent. Dr. Negar Asdaghi:         All right, so let's come now to the genetics of CAA. The apolipoprotein E gene is associated with the presence of amyloid angiopathy and development of lobar intracerebral hemorrhage, and we've learned about this in cases with cerebral amyloid angiopathy. Is there an association with ApoE, and did you find anything in this meta-analysis? Dr. Georgios Tsivgoulis: Another very exciting question. In 2007, there was a first report that the apolipoprotein ε4 homozygosity may be considered a risk factor for CAA-ri, and there was a strong correlation reporting a high prevalence of 77% of this apolipoprotein ε4 alleles among patients with CAA-ri. To justify this correlation, the hypothesis was that an underlying pathogenic mechanism, which increases the amyloid-β deposition and has a pro-inflammatory effect, may be suspected as the cause of this disorder. The largest, however, prospective cohort of CAA-ri patients conducted by Antolini and colleagues and was published in 2021 in Neurology, reported a much lower prevalence of apolipoprotein ε4 carriers accounting for 37%, 23% heterozygotes and 14% homozygotes. So, we also documented a pool prevalence of apolipoprotein ε4 homozygosity of 34%. So, we did not confirm the initial finding of 77%. However, in our meta-analysis, the homozygosity was 34%, and we need to have a cautious interpretation of these results because data is limited, and we need larger future population-based studies and in larger cohorts to evaluate the prevalence rate of these specific genetic markers. So, we can confirm an association between apolipoprotein ε4 homozygosity, however not as strong as originally reported in 2007. Dr. Negar Asdaghi:         OK. So, Georgios, thank you. And again, very important factor to keep in mind for our clinicians listening in. Unfortunately, based on what you mentioned, we don't have yet a genetic marker to, for sure, tell us if we're dealing with CAA-related inflammation, yes or no, as you mentioned. Just to recap, earlier on, there was studies to suggest a very strong association between apolipoprotein ε4 homozygosity and CAA-related inflammation. But later on, this was not confirmed by subsequent studies, and in your meta-analysis, you found 34% ApoE ε4 homozygosity amongst patients with CAA-related inflammation and could not confirm that original high association. OK, so with all of that, it's a lot of information. I have to go to the next question regarding controversies involving the levels of Aβ40, Aβ42, and P-tau proteins in CSF in the setting of CAA-related inflammation. Can you please tell us more about these biomarkers? Dr. Georgios Tsivgoulis: Yes. The overlap of Alzheimer's disease and CAA can be attributed to the coexistence of some degree of cerebrovascular amyloid deposition and amyloid plaque pathology, which is very common. And, of course, the evaluation of amyloid and tau proteins in CSF is of high significance for the prognosis and the evolution of CAA patients. In our previous review, we have summarized the literature and noticed that CSF concentrations of Aβ40 and, secondarily, Aβ42 were much lower in patients with cerebral amyloid angiopathy compared with Alzheimer's disease. Total tau and phospho-tau CSF levels were comparable to healthy controls in CAA and lower than patients with Alzheimer's disease. Moving now to CAA-ri, there were scarce data about these biomarkers amongst CAA-ri patients. The majority of the relevant studies have found relatively low levels of Aβ42 and Aβ40 in the CSF and high levels of P-tau. In the present meta-analysis, the pooled means of biomarker levels were based on the findings of only two studies with heterogeneity, and these limit substantially the validity of our observations. However, they confirm the previous reports indicating, as I said before, but I would like to repeat, low levels of Aβ42 and Aβ40 in the CSF and high levels of P-tau. Dr. Negar Asdaghi:         Perfect. So, thank you, Georgios. I'm going to recap what you said. So, we're talking about CSF biomarkers, and first what you mentioned is going back to the original studies concentrated on using these biomarkers as ways of differentiating between cerebral amyloid angiopathy and Alzheimer's disease. And very briefly, to recap what you said, in general, the levels of Aβ40 and, secondarily, Aβ42 was found to be much lower than the Alzheimer's levels in patients with CAA. Now coming to the inflammatory form of CAA, what you mentioned and what you found in this meta-analysis, practically speaking, confirmed that the levels of Aβ40 and Aβ42 in CSF are low and the levels of P-tau are high in this condition as well. So, one thing I want to ask as a secondary question to that is, that it sounds like these biomarkers are more or less similar in CAA and CAA -related inflammation, not that different. Is that correct? Dr. Georgios Tsivgoulis: It's absolutely correct. And I would also like to highlight a major limitation of the meta-analysis that we had available data from only two studies to pool the mean of these CSF biomarker levels. So, these results need to be acknowledged with caution, and we would love to repeat our meta-analysis after the publication of more studies and prospective cohorts measuring the CSF biomarkers in patients with CAA-ri. Dr. Negar Asdaghi:         OK. So, again, important to note, as you mentioned, that there's heterogeneity in data because of just paucity of information on this, but as we stand today, the biomarkers won't really help us in terms of differentiating between the two conditions that are CAA or CAA-related inflammation. And so, I think I've learned a lot from this interview myself, but I think we have to just talk briefly about the available therapies for CAA-related inflammation. Dr. Georgios Tsivgoulis: Yes. In our meta-analysis, we sought to summarize the available information regarding different therapeutic strategies and outcomes among CAA-ri patients. Our results supported our clinical experience indicating that corticosteroids represent the first-line treatment in these patients' outlook. Steroids have been associated with clinical and radiological improvement of the primary disease episode and decreased risk of subsequent relapses in patients with CAA-ri. Additional immunosuppressive therapies, including cyclophosphamide, mycophenolate mofetil, azathioprine, IVIG, or rituximab, have been also reported as adjunct therapies in selected cases with a more severe course of the disease. However, this is another limitation that needs to be acknowledged. That data regarding the treatment and the outcomes are limited and heterogeneous, which prevented us from drawing robust conclusions using a meta-analytical approach. And we believe that we need future cohort studies with prospective data validation in order to generate a proposal for a therapeutic algorithm management in these cases. Dr. Negar Asdaghi:         Thank you, Georgios. So, we have a condition that is now being more and more recognized. We now have criteria based on clinical and radiographic presentation features of patients that might help us with this diagnosis to differentiate it from cerebral amyloid angiopathy. And in terms of therapies, the idea is that the most studied drug is really just first-line therapy, that's corticosteroids. And then there's positive data regarding use of all other forms of immunosuppression, including, as you mentioned, cyclophosphamide, rituximab, and oral agents such as mycophenolate mofetil or azathioprine. We have limited information about those, but I want to highlight something you actually mentioned earlier on in the interview, which is the field is moving towards making these diagnoses based on clinical features and radiographic features that you had highlighted and actually giving patients immunosuppression early on and only move on to a biopsy if the patient had failed these therapies for a period of time, which you mentioned three weeks. So, I think it's important for us as clinicians to keep this evolving criterion and recommendations in mind. And before we end, I want to ask you a hypothetical question, Georgios. In your opinion, what's an ideal randomized trial for CAA-related inflammation in the future? Dr. Georgios Tsivgoulis: I think before going to the randomized, the ideal randomized trial for CAA-ri, and designing this trial, we need much more information regarding the underlying pathophysiological mechanisms. There are many unanswered questions. What is the diagnostic value of CSF biomarkers such as amyloid, we discussed earlier, and tau protein? And, of course, what is the value of CSF and the amyloid-β autoantibodies, if there is any? What is the value of genetic markers such as apolipoprotein E genotype and a correlation with the co-existing inflammation in CAA-ri? However, I don't want to defer this question. So, a typical answer would be that with regard to the ideal patients, we would want a young patient without comorbidities after the first manifestation of CAA-ri who has shown a good clinical and radiological response to corticosteroids in order to define the best second-line therapy. However, before answering all these questions in a clinical trial, if we can, I think that we need to understand the CSF and genetic biomarkers in order to uncover mechanisms regarding pathophysiology that can help us to design more targeted clinical trials studying novel disease-modifying treatments. Dr. Negar Asdaghi:         Thank you. Dr. Georgios, it's been a pleasure having you on the podcast, and I can say we've learned a lot. We look forward to having you back here and talk about that hypothetical randomized trial, and I'm sure one day hopefully will happen in our lifetime. Thank you for being here. Dr. Georgios Tsivgoulis: Thank you. Thank you for having me. It was a pleasure. Dr. Negar Asdaghi:         Thank you. Homer, the legendary Greek poet, described a case of dementia in his seminal work, The Odyssey, in the late eighth century before Christ. He described the cognitive decline of Odysseus's father, King Laertes. The detailed account of the king's mental decline, loss of short-term memory with retention of long-term memory combined with his depression and despair over the loss of his son, is dramatically accurate for a nearly 3,000-year-old description of dementia. Before I ended the interview, I had to use this opportunity to ask Georgios about lessons learned from ancient Greeks and this seemingly timeless disease. Dr. Georgios Tsivgoulis: Thank you for this question. King Laertes was indeed Odysseus's father, and it's a great paradigm describing dementia. However, the ancient history of dementia may be separated according to the Greek philosopher Posidonius in two periods. The first period is called dementia appearing due to old age, which is called in Greek, eros. And the second one is dementia appearing in other ages and mainly due to other reasons, called morosis. Posidonius of Rhodes was a Greek stoic philosopher of the second first century BC who strongly believed and suggested that morosis, which is that dementia appearing in younger ages due to other disorders, should be treated immediately after its onset. So, if I would like to end this podcast, I would just suggest that CAA-ri could be classified as morosis according to Posidonius. And what we could learn is that the early diagnosis is essential since the prompt initiation of corticosteroids should not be unreasonably delayed. Dr. Negar Asdaghi:         And this concludes our podcast for the January 2023 issue of Stroke. Please be sure to check this month's table of contents for the full list of publications, including a series of Focused Updates on post-stroke neurological recovery, from management of post-stroke attention deficit, neglect and apraxia to post-stroke memory decline. And with this, we end the start of our 2023 podcast series. Like all new things, a new beginning can come with new directions, and sometimes a new direction is all that we need. After all, as the legend has it, it was a direction of that falling apple back in the year 1666 that gave Isaac Newton the idea of the universal law of gravitation. Now, Isaac Newton has, without a doubt, given science some of its biggest discoveries in mathematics, physics, and astronomy. But most may not know that Newton had a pretty rough start in life. A January-born premature baby, he was thought not to survive the first few days of life. Newton had a difficult childhood, and at the age of 16, he was pulled out of school by his family and forced to become a farmer, a job he didn't like and he was miserably bad at. So, as we start a new year, let's remember that even the smartest people are not good at everything, and it does take time to find one's passion in life. Now, while things may not always be clear, what is clear is that a great way to find that center of gravity is, as always, staying alert with Stroke Alert. This podcast is produced by Wolters Kluwer and supported by the editorial team of Stroke. Our Stroke Alert podcast and production staff includes Danielle Cross, Eric Goldstein, Nastajjia Krementz, Ishara Ratnayaka, Erinn Cain, Rebecca Seastrong, and Negar Asdaghi. This program is copyright of the American Heart Association, 2023. The opinions expressed by speakers in this podcast are their own and not necessarily those of the editors or of the American Heart Association. For more, visit AHAjournals.org.

Body Breaking Free
82. Live Life with Flair / Stephanie Hunt

Body Breaking Free

Play Episode Play 30 sec Highlight Listen Later Jan 18, 2023 62:47


Stephanie Hunt has been a licensed interior designer for more than two decades and is the founder of the lifestyle brand, Flairhunter.  Today's episode we talk about entrepreneurship, intuitive eating and (her new) podcast! Stephanie will certainly radiate passion into your day.  I can't wait for you to listen! Make sure to sign-up for our newsletter to be with our community and stay updated! ~ katiekaygraham.com/newsletterGUEST CONTACTIG: @theflairhunter Mail: stephanie@flairhunter.com Website: https://theflairhunter.comPodcast: Cult of Flair (coming soon!) Follow Stephanie to keep updated for podcast launch!SUPPORT US:Share it with a friend! Support by spreading the word!Rate & Review: (1) Go to Library (2) Go to Show *not episode* (3) Scroll down to "Ratings and Reviews (3) Click "Write a ReviewADD ME ON:Website: https://katiekaygraham.com/IG: @katiekaygrahamNewsletter: katiekaygraham.com/newsletterBODY BREAKING FREE LISTEN ON: Apple Podcast | Spotify Podcast | Audible

WhatCulture Wrestling
WWE SmackDown Review - Battle Of The MONSTERS! Kevin Owens Vs. Sami Zayn! Karrion Kross Chokes Out Rey Mysterio! Bray Wyatt Hits The Reset Button?!

WhatCulture Wrestling

Play Episode Listen Later Jan 16, 2023 62:47


Adam and Michael chat about what happened on this week's episode of Friday Night SmackDown, including...Battle of the MONSTERS!Kevin Owens vs. Sami Zayn!Karrion Kross chokes out Rey Mysterio!Flair and Deville BRAWL!Bray Wyatt hits the reset button?!ENJOY!Follow us on Twitter:@AdamWilbourn@MSidgwick@WhatCultureWWEFor more awesome content, check out: whatculture.com/wwe Hosted on Acast. See acast.com/privacy for more information.

PWTorch Dailycast
PWTorch Dailycast – PWTorch ‘90s Pastcast - Moynahan & McDonald discuss issue #208 (1-4-93) of the PWTorch incl. Vader beats Simmons, more

PWTorch Dailycast

Play Episode Listen Later Jan 14, 2023 124:09


Patrick Moynahan and Alex McDonald kick off the fifty-second episode of PWTorch ‘90s Pastcast discussing issue #208 of the PWTorch including news of Vader's second WCW title reign, Flair possibly headed for WCW, changes to the Clash ThunderCage main event, Lex Luger's upcoming WWF debut, Alex answers Royal Rumble trivia, and so much more. Email us questions or comments at torchpastcast@gmail.com.

Cultaholic
WCW Nitro #31 | Hulk Hogan Is UNSTOPPABLE, Flair And The Giant Face Lex Luger And Sting | CULTAHOLIC CLASSIC NITRO REVIEW

Cultaholic

Play Episode Listen Later Jan 12, 2023 70:08


Nitro #31 | Apr. 15th, 1996: Hulk Hogan looks to overcome the odds when he faces "The Taskmaster" Kevin Sullivan & Arn Anderson in a Handicap Match. "Nature Boy" Ric Flair joins forces with The Giant to face Sting & Lex Luger. "Macho Man" Randy Savage battles Earl Robert Eaton. Public Enemy face The Nasty Boys in an Anything Goes Street Fight and much more.Sam Driver and Tom Campbell travel back in their Slim Jim-Powered DeLoreon to watch every single episode of WCW Monday Nitro from the very beginning to the bitter end. Hosted on Acast. See acast.com/privacy for more information.

Ric Flair Wooooo Nation Uncensored
Vince Is Back!

Ric Flair Wooooo Nation Uncensored

Play Episode Listen Later Jan 11, 2023 57:30 Very Popular


On this episode of To Be The Man, Ric and Conrad discuss the debacle of the College National Championship, Sasha Bank's return to professional wrestling, the heat Jeff Jarrett is getting from AEW fans, and the return of the chairman Vince McMahon! TITAN NUTRITION - Enlite comes in 6 amazing flavors that can be easily mixed and taken on the go. Find it at TitanNutrition.net and save 10% plus get free shipping when you use code FLAIR at checkout. That's TitanNutrition.net code FLAIR for 10% and free shipping! JIMMYS FAMOUS SEAFOOD - JimmysFamousSeafood.com ships nationwide. Free 2-day nationwide shipping on orders over $125 (excluding steamed crabs and fresh items) use the promo code: FLAIR RIC FLAIR DRIP - Wanna have that DRIP? Well, now you can get it over at RicFlairDrip.com RIC FLAIR SHOP - Style and Profile like the Nature Boy with some gear from RicFlairShop.com WOOOOO WINGS - Wooooo! Wings, a virtual restaurant concept from The Man himself, the Nature Boy Ric Flair. Enjoy the legendary flavors and world championship wings by ordering with your Uber Eats or Postmates app.  Wooo Wings is now open in Nashville, San Antonio, Jacksonville, Florida as well as Huntsville and Tuscaloosa in Alabama, with many more locations coming soon.  Try the only chicken wings worthy of carrying the name of the 16x World Heavyweight Champion. SAVE WITH CONRAD - Start saving money right now with help from your friends at SaveWithConrad.com Get early, ad-free access to more than a dozen of your favorite wrestling podcasts, starting at just $9 over on AdFreeShows.com. That's less than 15 cents an episode each month! You can also listen to them directly through Apple Podcasts or your other regular podcast apps! AdFreeShows.com also has thousands of hours worth of bonus content including popular series like Title Chase, Eric Fires Back, Conversations with Conrad, Mike Chioda's Mailbag and many more! Plus, live, interactive virtual chats with your favorite podcasts hosts and wrestling legends. All that and much more! Sign up today at AdFreeShows.com! Learn more about your ad choices. Visit megaphone.fm/adchoices

PWTorch Dailycast
PWTorch Dailycast – PWTorch ‘90s Pastcast - Moynahan & McDonald discuss issue #207 (12-28-92) of the PWTorch incl. full review of Starrcade

PWTorch Dailycast

Play Episode Listen Later Jan 7, 2023 161:37


Patrick Moynahan and Alex McDonald kick off the fifty-first episode of PWTorch ‘90s Pastcast discussing issue #207 of the PWTorch including a full review of Starrcade 1992 and the logic behind the show's booking, questioning Sting's greatest opponent, discussing Flair possibly leaving WWF, and so much more. Email us questions or comments at torchpastcast@gmail.com.