JAMAevidence JAMA Guide to Statistics and Methods

Follow JAMAevidence JAMA Guide to Statistics and Methods
Share on
Copy link to clipboard

Interviews with authors of JAMA Guide to Statistics and Methods chapters about common and new statistics and methods used in clinical research and reported in medical journals.

JAMA Network


    • Apr 3, 2025 LATEST EPISODE
    • monthly NEW EPISODES
    • 18m AVG DURATION
    • 36 EPISODES


    More podcasts from JAMA Network

    Search for episodes from JAMAevidence JAMA Guide to Statistics and Methods with a specific topic:

    Latest episodes from JAMAevidence JAMA Guide to Statistics and Methods

    Nonparametric Statistical Analysis With Dr Lachin

    Play Episode Listen Later Apr 3, 2025 11:56


    John M. Lachin, ScD, Biostatistics Center, George Washington University, discusses Nonparametric Statistical Analysis with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Nonparametric Statistical Analysis

    The Use of Historical Controls in Clinical Trials, With Dr Althouse

    Play Episode Listen Later Feb 6, 2025 20:45


    Andrew D. Althouse, PhD, University of Pittsburgh School of Medicine discusses The Use of Historical Controls in Clinical Trials with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: The Use of Historical Controls in Clinical Trials

    Futility in Clinical Trials With Dr Wendelberger

    Play Episode Listen Later Dec 5, 2024 15:10


    Barbara Wendelberger, PhD, Berry Consultants, discusses Futility in Clinical Trials with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Futility in Clinical Trials

    Interim Analyses During Group Sequential Trials With Dr Meurer

    Play Episode Listen Later Nov 7, 2024 16:14


    William J. Meurer, MD, MS, University of Michigan Medical School, discusses Interim Analyses During Group Sequential Trials with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Interim Analyses During Group Sequential Clinical Trials

    Genome-Wide Association Studies With Dr Rotter

    Play Episode Listen Later Sep 5, 2024 23:26


    Jerome I. Rotter, MD, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, Department of Pediatrics, Harbor-UCLA Medical Center, discusses Genome-Wide Association Studies with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Genome-Wide Association Studies

    Conditional Power: How Likely Is Trial Success?

    Play Episode Listen Later Aug 1, 2024 16:28


    Benjamin R. Saville, PhD, Department of Biostatistics, Vanderbilt University Medical Center, discusses Conditional Power: How Likely Is Trial Success? with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Conditional Power

    Bayesian Hierarchical Models With Dr McGlothlin

    Play Episode Listen Later Jul 3, 2024 15:07


    Anna E. McGlothlin, PhD, Berry Consultants, LLC, discusses Bayesian Hierarchical Models with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Bayesian Hierarchical Models

    Sequential, Multiple Assignment, Randomized Trial Designs With Dr Kidwell

    Play Episode Listen Later Jun 6, 2024 13:27


    Kelley Kidwell, PhD, professor of biostatistics, University of Michigan, discusses Sequential, Multiple Assignment, Randomized Trial Designs with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Sequential, Multiple Assignment, Randomized Trial Designs

    Target Trial Emulation for Causal Inference From Observational Data With Dr Hernán

    Play Episode Listen Later May 2, 2024 27:25


    Miguel A. Hernán, MD, DrPH, professor of epidemiology, Harvard T.H. Chan School of Public Health, discusses Target Trial Emulation: A Framework for Causal Inference From Observational Data with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Target Trial Emulation

    On Deep Learning for Medical Image Analysis With Dr Carin

    Play Episode Listen Later Apr 4, 2024 22:54


    JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses On Deep Learning for Medical Image Analysis with Lawrence Carin, PhD. Related Content: On Deep Learning for Medical Image Analysis

    Patient-Reported Outcome Measures in Clinical Research With Drs Weinfurt and Reeve

    Play Episode Listen Later Mar 7, 2024 22:10


    JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Patient-Reported Outcome Measures in Clinical Research with Kevin P. Weinfurt, PhD, and Bryce B. Reeve, PhD. Related Content: Patient-Reported Outcome Measures in Clinical Research

    phd patients md clinical research reeve patient reported outcome measures
    Immortal Time Bias in Observational Studies With Dr Kabir Yadav

    Play Episode Listen Later Jan 4, 2024 15:06


    JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Immortal Time Bias in Observational Studies with Kabir Yadav, MDCM, MS, MSHS. Related Content: Immortal Time Bias in Observational Studies

    Adjustment for Baseline Characteristics in Randomized Clinical Trials

    Play Episode Listen Later Dec 7, 2023 18:15


    JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Adjustment for Baseline Characteristics in Randomized Clinical Trial with Lars W. Andersen, MD, MPH, PhD, DMSc. Related Content: Adjustment for Baseline Characteristics in Randomized Clinical Trials

    Odds Ratios—Current Best Practice and Use With Dr Norton

    Play Episode Listen Later Nov 2, 2023 12:19


    JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Odds Ratios—Current Best Practice and Use with Edward C. Norton, PhD. Related Content: Odds Ratios—Current Best Practice and Use Types and Distribution of Payments From Industry to Physicians in 2015

    Estimands, Estimators, and Estimates With Dr Little

    Play Episode Listen Later Aug 3, 2023 22:06


    Roger J. Lewis, MD, PhD, discusses Estimands, Estimators, and Estimates with Roderick J. Little, PhD, in the JAMA Guide to Statistics and Methods series. Related Content: Estimands, Estimators, and Estimates

    Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses With Dr Smith

    Play Episode Listen Later May 4, 2023 18:25


    Roger J. Lewis, MD, PhD, discusses Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses with Valerie A. Smith, DrPH. Related Content: Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses of Clinical Trials

    Time-to-Event Analysis With Dr Tolles

    Play Episode Listen Later Mar 3, 2023 11:19


    JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Time-to-Event Analysis with Juliana Tolles, MD, MHS. Related Content: Time-to-Event Analysis

    Adjusting for Nonadherence or Stopping Treatments With Drs Adler and Latimer

    Play Episode Listen Later Jan 5, 2023 17:58


    JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Adjusting for Nonadherence or Stopping Treatments with Amanda I. Adler, MD, PhD, and Nicholas Latimer, PhD. Related Content: Adjusting for Nonadherence or Stopping Treatments in Randomized Clinical Trials

    phd md treatments stopping adjusting adler latimer randomized clinical trials nonadherence
    Worst-Rank Score Methods—A Nonparametric Approach to Informatively Missing Data With Dr Lachin

    Play Episode Listen Later Nov 3, 2022 17:06


    JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Worst-Rank Score Methods—A Nonparametric Approach to Informatively Missing Data with John M. Lachin, ScD. Related Content: Worst-Rank Score Methods—A Nonparametric Approach to Informatively Missing Data

    Using Latent Class Analysis to Identify Hidden Clinical Phenotypes With Dr Heather G. Allore

    Play Episode Listen Later Sep 1, 2022 17:34


    JAMA Statistical Editor Roger Lewis, MD, PhD, discusses Using Latent Class Analysis to Identify Hidden Clinical Phenotypes with Heather G. Allore, PhD. Related Content:

    Use of Run-in Periods in Randomized Trials With Dr Armitage

    Play Episode Listen Later May 5, 2022 19:29


    JAMA Statistical Editor Roger Lewis, MD, PhD, discusses Use of Run-in Periods in Randomized Trials with Jane M. Armitage, MBBS. Related Content: Use of Run-in Periods in Randomized Trials With Dr Armitage Short- and Long-term Effects of a Mobile Phone App in Conjunction With Brief In-Person Counseling on Physical Activity Among Physically Inactive Women: The mPED Randomized Clinical Trial

    Regression Discontinuity Study Design to Estimate Observational Differences With Dr Maciejewski

    Play Episode Listen Later Apr 7, 2022 17:54


    JAMA Statistical Editor Roger Lewis, MD, discusses Regression Discontinuity Design with Matthew L. Maciejewski, PhD. Related Content: Regression Discontinuity Design Using Instrumental Variables to Address Bias From Unobserved Confounders

    Case-Control Studies: Using “Real-world” Evidence to Assess Association, With Dr Irony

    Play Episode Listen Later Dec 2, 2021 23:07


    JAMA Statistical Editor Roger Lewis, MD, discusses Case-Control Studies: Using “Real-world” Evidence to Assess Association, With Dr Irony.

    Equipoise in Research—Integrating Ethics and Science in Human Research

    Play Episode Listen Later Oct 7, 2021 21:48


    Roger J. Lewis, MD, PhD, discusses Equipoise in Research—Integrating Ethics and Science in Human Research with Alex John London, PhD Related Content: Equipoise in Research—Integrating Ethics and Science in Human Research

    Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials

    Play Episode Listen Later Sep 2, 2021 27:31


    Roger J. Lewis, MD, PhD, discusses Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials with Melanie Quintana, PhD Related Content: Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial Incorporating Adult Evidence Into Pediatric Research and Practice: Bayesian Designs to Expedite Obtaining Child-Specific Evidence

    death phd md results clinical trials interpret bayesian analysis roger j lewis
    Cost-effectiveness Analysis for Clinicians

    Play Episode Listen Later Aug 5, 2021 18:21


    Cost-effectiveness analysis defines trade-offs between costs, harms, and benefits of alternative treatments and combines them into a single metric, the incremental cost-effectiveness ratio (ICER), that can inform decisions about which interventions to recommend when limited resources are available. Gillian Sanders-Schmidler, PhD, professor of population health sciences and medicine at Duke University, explains the method in terms clinicians can understand. Related Article: Cost-effectiveness Analysis for Clinicians

    Multiple Comparison Procedures from the JAMA Guide to Statistics and Methods

    Play Episode Listen Later Mar 4, 2021 22:47


    JAMA Deputy Editor Edward Livingston, MD, discusses "Multiple Comparison Procedures" with Dr. Jing Cao, PhD

    Logistic Regression—What It Is and How to Use It in Clinical Research

    Play Episode Listen Later Jan 7, 2021 32:47


    Logistic regression is one of the most commonly used statistical analytic tools in the medical literature. William Meurer, MD, from the University of Michigan, and Juliana Tolles, MD, from UCLA, discuss a JAMA Guide to Statistics and Methods article they wrote entitled “Logistic Regression Diagnostics: Understanding How Well a Model Predicts Outcomes.” Related Article: Logistic Regression

    Randomization in Clinical Trials from the JAMA Guide to Statistics and Methods

    Play Episode Listen Later Dec 3, 2020 23:14


    Roger J. Lewis, MD, PhD, discusses Randomization in Clinical Trials from the JAMA Guide to Statistics and Methods Related Article(s): Randomization in Clinical Trials

    The Stepped-Wedge Clinical Trial: Evaluation by Rolling Deployment

    Play Episode Listen Later Sep 3, 2020 18:07


    Cluster randomized trials are performed when an intervention must be delivered to a group of patients like when testing new nursing protocols on award or different means for cleaning beds on a ward. One type of cluster trials is called a stepped-wedge where every cluster in the study ultimately undergoes the intervention. How this works it is explained by Susan Ellenberg, PhD, from the Department of Biostatistics, Epidemiology, and Informatics at the University of Pennsylvania School of Medicine. Related Article: The Stepped-Wedge Clinical Trial

    Minimal Clinically Important Difference: Defining What Really Matters to Patients

    Play Episode Listen Later Aug 6, 2020 11:43


    JAMA Deputy Editor Edward Livingston, MD, discusses Minimal Clinically Important Difference: Defining What Really Matters to Patients with Anna E. McGlothlin, PhD

    Sample Size Calculation for a Hypothesis Test With Dr Lynne Stokes

    Play Episode Listen Later Jul 2, 2020 12:14


    One of the most common causes for problems we see in manuscripts at JAMA is an inappropriately calculated study sample size. This seemingly mysterious process is explained by Lynne Stokes, PhD, professor of Statistical Science at Southern Methodist University in Dallas, Texas.

    Pragmatic Trials: Practical Answers to “Real-world” Questions With Harold C. Sox, MD

    Play Episode Listen Later Jun 25, 2020 21:14


    JAMA Deputy Editor Edward Livingston, MD, discusses Pragmatic Trials: Practical Answers to “Real-world” Questions with Harold C. Sox, MD, of PCORI

    Cluster Randomized Trials: Evaluating Treatments Applied to Groups With William J. Meurer, MD

    Play Episode Listen Later May 7, 2020 23:39


    JAMA Deputy Editor Edward Livingston, MD, discusses "Cluster Randomized Trials: Evaluating Treatments Applied to Groups" with William J. Meurer, MD, MS

    Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Dr Amy Kaji

    Play Episode Listen Later Feb 6, 2020 10:52


    Ed Livingston, MD, FACS, AGAF, discusses Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Amy Kaji, MD, PhD

    JAMA Guide to Statistics and Methods

    Play Episode Listen Later Dec 5, 2019 13:43


    Clinical researchers and biostatisticians use highly specialized language to help them discuss statistics and research methods efficiently. In 2019 JAMA published the JAMA Guide to Statistics and Methods, a book of short reviews that translate that specialized language and explain statistics and methods to a broad physician readership. The book's editors and authors, Edward Livingston, MD, and Roger J. Lewis, MD, PhD, discuss their approach to choosing statistical topics and their objectives in compiling the reviews into book format.   Purchase the JAMA Guide to Statistics and Methods at: McGraw-Hill:                    ja.ma/StatsGuideMH Barnes and Noble:           ja.ma/StatsGuideBN Amazon:                            ja.ma/StatsGuideAmazon

    Claim JAMAevidence JAMA Guide to Statistics and Methods

    In order to claim this podcast we'll send an email to with a verification link. Simply click the link and you will be able to edit tags, request a refresh, and other features to take control of your podcast page!

    Claim Cancel