Podcasts about Real world evidence

Why Real-World Use Doesn't Replace Trials; Placebo Effect and Clinical Trial Necessity; Raw Data Ownership Enables Manipulation; Empowering Patients Through Labels and Questions; Reading Drug Labels Reveals True Efficacy; Product Monographs as Trusted Resources; Many Widely Used Drugs Lack Long-Term Data; Limited Access to Raw Trial Data Even Through Labels; Therapeutics Initiative Offers Publicly Accessible Evidence; System Manipulation Persists in 2025; Covid Boosters Approved Without Efficacy Trials #PharmaTruth #EvidenceBased #MedicalEthics #HealthTalks

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/MZC865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until December 30, 2026.Revealing New Sequences in CLL: Collaborative Care Planning With Real-World Evidence and Modern Therapeutics In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and CLL Society. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/MZC865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until December 30, 2026.Revealing New Sequences in CLL: Collaborative Care Planning With Real-World Evidence and Modern Therapeutics In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and CLL Society. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/MZC865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until December 30, 2026.Revealing New Sequences in CLL: Collaborative Care Planning With Real-World Evidence and Modern Therapeutics In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and CLL Society. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/MZC865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until December 30, 2026.Revealing New Sequences in CLL: Collaborative Care Planning With Real-World Evidence and Modern Therapeutics In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and CLL Society. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

David Alain Wohl, MD - Inpatient Management of SARS-CoV-2 Infection: Applying Learnings From Real World Evidence to Real World Practice

David Alain Wohl, MD - Inpatient Management of SARS-CoV-2 Infection: Applying Learnings From Real World Evidence to Real World Practice

David Alain Wohl, MD - Inpatient Management of SARS-CoV-2 Infection: Applying Learnings From Real World Evidence to Real World Practice

David Alain Wohl, MD - Inpatient Management of SARS-CoV-2 Infection: Applying Learnings From Real World Evidence to Real World Practice

David Alain Wohl, MD - Inpatient Management of SARS-CoV-2 Infection: Applying Learnings From Real World Evidence to Real World Practice

David Alain Wohl, MD - Inpatient Management of SARS-CoV-2 Infection: Applying Learnings From Real World Evidence to Real World Practice

Research is more than just finding interesting stats. It's about finding better ways to deliver savings, simplicity, and support. In this episode, you'll hear from managed care pharmacy researchers who are doing just that, delivering data driven insights to drive affordability and access in health care.  Pat Gleason, PharmD, BCPS, FCCP, FAMCP, assistant vice president of health outcomes; Nick Friedlander, PharmD, clinical program pharmacist; and Simone Ndujiuba, PharmD, BCOP, clinical oncology pharmacist senior principal; and host Alex Cook, senior public relations manager, discuss how Prime's research helps address affordability and accessibility issues and guides health care providers and peers toward clarity on treatment for complex health conditions. Research topics covered:Three-Year Real-World Adherence and Persistence to Glucagon-Like Peptide-1 Receptor Agonists Among Commercially Insured Adults with Obesity without Diabetes Trends in Real-World Persistence to Weight Loss Glucagon-Like Peptide-1 Receptor Agonists from 2021 to 2024 Among Commercially Insured Adults without Diabetes — This study earned a platinum award from AMCP.  Impact of a Medical Claims Automated Glucagon Like Peptide-1 Drugs Prior Authorization Program— This study earned a gold award from AMCP.Validation of Long-term Savings from a Pharmacist-to-Prescriber Telephonic Intervention — This study earned a gold award from AMCP. Total Cost of Care and Adverse Effects Assessment of Bispecific T-cell Engagers and Chimeric Antigen Receptor T-cell Therapies for Relapsed Refractory Follicular Lymphoma  -------------------------Content in this podcast is for informational or educational purposes only.The content also does not substitute professional medical advice or consultations with health care professionals. Always seek advice from a physician or other health care providers with any questions you have regarding a medical treatment or condition before undertaking a new health care regimen.

Real-World Evidence (RWE) is transforming how regulators evaluate medical devices — but many manufacturers still struggle to use it correctly. In this episode, we break down what RWE really means, how it differs between the FDA and the EU MDR, and how you can design a compliant, global strategy that turns data into regulatory strength. You'll learn: What qualifies as Real-World Data (RWD) and Real-World Evidence (RWE) How the FDA integrates RWE into premarket submissions (510(k), De Novo, PMA) How EU MDR uses RWE through PMCF and PMS The key differences in approach between the two regions A practical 5-step roadmap to build a compliant RWE strategy Common pitfalls (bias, poor traceability, privacy issues) — and how to avoid them

Large language models are increasingly used to turn complex study output into plain-English summaries. But how do we know which models are safest and most reliable for healthcare? In this most recent community AI research paper reading, Arjun Mukerji, PhD – Staff Data Scientist at Atropos Health – walks us through RWESummary, a new benchmark designed to evaluate LLMs on summarizing real-world evidence from structured study output — an important but often under-tested scenario compared to the typical “summarize this PDF” task.Learn more about AI observability and evaluation, join the Arize AI Slack community or get the latest on LinkedIn and X.

CME credits: 1.00 Valid until: 16-09-2026 Claim your CME credit at https://reachmd.com/programs/cme/Real-World-Evidence-of-Photobiomodulation-Efficacy-in-Ocular-Indications/35952/ This CME activity focuses on multiwavelength photobiomodulation (PBM), an emerging therapy indicated for the treatment of dry age-related macular degeneration (AMD). Hear from leading researchers and retina specialists about the mechanism of action, how it is administered, its efficacy and safety profile, therapeutic durability, which patients may benefit the most, and how PBM would fit into the AMD treatment paradigm.

CME credits: 1.00 Valid until: 16-09-2026 Claim your CME credit at https://reachmd.com/programs/cme/Real-World-Evidence-of-Photobiomodulation-Efficacy-in-Ocular-Indications/35952/ This CME activity focuses on multiwavelength photobiomodulation (PBM), an emerging therapy indicated for the treatment of dry age-related macular degeneration (AMD). Hear from leading researchers and retina specialists about the mechanism of action, how it is administered, its efficacy and safety profile, therapeutic durability, which patients may benefit the most, and how PBM would fit into the AMD treatment paradigm.

Nobody knows ALS better than people living with the disease. Therefore, it’s crucial for scientists to utilize the perspectives of people with lived experience in their research. Earlier this year, ALS TDI joined with Her ALS Story—a group of women diagnosed with ALS before the age of 35—to put on a series of Town Hall webinars that highlighted the importance of this connection. The three-part series featured discussions about ALS risk factors, lesser-known symptoms, and stories of diagnosis. In each session, researchers from ALS TDI’s ALS Research Collaborative, or ARC Study, presented information about our current scientific understanding of each topic, while Her ALS Story members shared their own personal experiences. Today, on Endpoints, we’ll hear some highlights from each episode of the series. We’ll also be joined by Dr. Danielle Boyce, ALS TDI’s Principal Investigator, Real World Evidence, and Alan Premasiri, our Director of Clinical Operations, to discuss what they learned from the discussions and how conversations like these can help shape the way they approach their research. If you'd like to learn more about ALS TDI's research and how we are incorporating lived experience to advance research, consider attending the ALS TDI Summit on October 17th, 2025 in Boston, MA or online. Register here: https://fundraise.als.net/alssummit/Support the show: https://www.als.net/donate/See omnystudio.com/listener for privacy information.

Host: Jennifer Caudle, DO Guest: Blen Girmay, MD Because standard-dose vaccines usually produce only modest immunogenic responses in people age 65 years and older, the Advisory Committee on Immunization Practices, as of June 2022, recommended this age group receive either an adjuvanted or higher-dose seasonal influenza vaccine.1,2,3 A pragmatic, head-to-head randomized study compared FLUAD and the high-dose influenza vaccine over the course of two influenza seasons.2 Joining Dr. Jennifer Caudle to discuss this study and its findings from the first season (2023-2024) is Dr. Blen Girmay, a Johns Hopkins fellowship-trained primary care geriatrician at Inova Health System in Fairfax, Virginia. References: Coleman BL, Sanderson R, Haag MDM, McGovern I. Effectiveness of the MF59-adjuvanted trivalent or quadrivalent seasonal influenza vaccine among adults 65 years of age or older, a systematic review and meta-analysis. Influenza Other Respir Viruses. 2021;15(6):813-823. Klein N. Oral presentation presented at: IDWeek 2024 Meeting; October 16-19, 2024. Los Angeles, CA. Grohskopf LA, Ferdinands JM, Blanton LH, Broder KR, Loehr J. Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024-25 Influenza Season. MMWR Recomm Rep. 2024;73(5):1-25.

The FDA Group's Nick Capman sits down with Dr. Manfred Stapff—physician, author, and founder of Candid Advisory Inc., a consultancy specializing in real-world evidence and clinical development—for a wide-ranging conversation about how real-world data is reshaping drug development, regulatory decisions, and public understanding of evidence.Dr. Stapff draws on decades of experience across medical affairs, clinical trials, and RWE analytics to explain why real-world evidence isn't a replacement for randomized controlled trials—but a necessary complement. He outlines how to transform raw data into credible evidence, how the FDA is using RWE today, and why quality, transparency, and context are essential in data-driven science.He also offers cautionary insight on common pitfalls—from bias in training data and misinterpreted statistics to the challenges of AI integration in healthcare research.What they cover:What real-world evidence is (and isn't)—and how it differs from clinical trial dataHow RWE is being used by the FDA to support label expansions and safety monitoringKey risks around self-reported data, upcoding, and poor data qualityWhy statistical significance isn't enough—and how to evaluate clinical relevanceHow AI can accelerate pattern recognition and predictive diagnosticsWhy training data matters—and how bias can infiltrate large-scale AI toolsThe role of educated skepticism in interpreting data-driven claims in both science and societyDr. Manfred Stapff is the founder and principal consultant at a boutique advisory firm focused on real-world evidence strategy, clinical development, and medical data intelligence. He is the author of Real World Evidence Unveiled and a frequent speaker on the role of data integrity, statistical literacy, and AI in advancing medical research. His current work supports life science companies and investors in evaluating drug development strategies, acquisition opportunities, and data-driven innovations.The FDA Group helps life science organizations rapidly access the industry's best consultants, contractors, and candidates. Our resources assist in every stage of the product lifecycle, from clinical development to commercialization, with a focus in Quality Assurance, Regulatory Affairs, and Clinical Operations. For project or resource needs, visit ⁠⁠https://www.thefdagroup.com⁠⁠

This panel was recorded June 26, 2025.⁠⁠⁠⁠ We hope you'll join us live in the future to ask your own questions and participate in the attendee chat! See similar events on demand and read other free MedTech resources at RQMplus.com.SummaryHear leading neurology innovators discuss how to navigate complex regulatory pathways, accelerate approvals, and reduce risk in bringing groundbreaking neurological devices to market.LinkedIn panelist and moderator profiles 

From defining what real-world evidence is to discussing its impact on cancer drug approvals, comparative effectiveness, and synthetic data, Dr. Winson Cheung shares insights with Dr. Aly-Khan Lalani and Dr. Christopher Wallis that every clinician should know.The View on GU with Lalani & Wallis integrates key clinical data from major conferences and high impact publications, sharing meaningful take home messages for practising clinicians in the field of genitourinary (GU) cancers. Learn more about The View on GU: theviewongu.caThis podcast has been made possible through unrestricted financial support by Novartis, Bayer, Astellas, Tolmar, Ipsen, J&J, Merck, Pfizer, Eisai and AbbVie.

In this keynote episode, Professor Sebastian Schneeweiss from Harvard Medical School shares groundbreaking insights from his extensive research into emulating randomized controlled trials (RCTs) using real-world data (RWD). Recorded live at The Effective Statistician Conference 2024, this talk explores whether non-randomized studies based on electronic health records and claims data can reach conclusions as reliable as those from traditional RCTs. Prof. Schneeweiss, also Chief of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women's Hospital, walks us through the RCT DUPLICATE project, a major FDA-funded initiative that evaluated whether regulatory decisions could be replicated through high-quality real-world evidence (RWE). From the successes to the limitations—and everything in between—this episode is packed with lessons for statisticians, regulators, and pharmaceutical leaders interested in the future of data-driven healthcare decisions.

While few doubt the opportunity represented by real-world evidence, some concerns remain about its validity compared to traditional forms of clinical evidence, particularly among regulators. To address these concerns, IQVIA Consumer Health's vice president of global research and development and real-world evidence services, Volker Spitzer, suggests that incorporating some elements of traditional trials, such as randomization, is a good way to persuade regulators that RWE can be used for consumer health innovation, for example in generating new claims or supporting Rx-to-OTC switch. Looking forward, Spitzer is excited about the ways in which digital health tools and artificial intelligence can be used to expand the scope of RWE as well as drive personalization for consumers. Timestamps: 3:00 - Addressing concerns about RWE's scientific rigour and validity 12:00 – Regulators' views of RWE, particularly for consumer health 16:00 – Use of RWE for Rx-to-OTC switch 22:00 – The future of RWE Guest Bio: Volker Spitzer has more than 30 years of R&D experience spanning the consumer health sector, ingredients industry, and academia. Beginning his career as a professor in pharmaceutical sciences, he ascended to global positions encompassing R&D, innovation, licensing/M&A, and medical marketing at firms like Roche, DSM Nutritional Products, and Bayer. Since October 2017, Spitzer has been affiliated with IQVIA Consumer Health, serving as the vice president for global R&D and RWE Services. His purview primarily includes clinical research, RWE, virtual trials, and the burgeoning field of digital health. He has penned over 80 scientific publications, whitepapers and textbooks centered on science and innovation.

Episode DescriptionAudra Moran is the President and CEO of OCRA—Ovarian Cancer Research Alliance—which means she spends her days doing things most of us wouldn't survive five minutes doing: merging nonprofits, leading national patient support programs, funding lifesaving research, surviving pharma grant hell, and trying to reach every woman in America who might be slipping through the cracks. We talk about her time working with the Helen Keller National Center (yes, she knows finger spelling), her accidental journey into cancer nonprofit leadership, the weirdness of dermoid cysts, the ridiculousness of writing grants, and the absolute hellscape of diagnosis delay. Oh, and the fallopian tubes. You'll never look at them the same way again.This episode is funny, raw, deeply personal, and loaded with Gen X movie references and random facts about Paul Rudd, Terminator 2, and flipbook apps at 3am. Audra drops wisdom, humility, and a few hot takes on AI, advocacy, and what it really means to lead when the boulder keeps rolling downhill.RELATED LINKSAudra Moran on LinkedInOvarian Cancer Research Alliance (OCRA)Audra's profile on OCRACURE Today interview: Leading the FightOCRA + AI & Data: Overlooked PodcastFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In part 2 of a critical two-part series, Etienne Nichols and regulatory affairs expert Mike Drues explore the nuanced pathway of switching a medical device from prescription (Rx) to over-the-counter (OTC). This episode dives deep into what triggers a new submission, how usability testing and human factors play an expanded role for lay users, and the regulatory logic that guides these transitions. The conversation highlights the importance of aligning regulatory strategy with business goals, and offers practical insights on leveraging real-world evidence, understanding the limits of FDA databases, and optimizing pre-submission meetings.Key Timestamps02:10 – Starting from a cleared 510(k): Do you need a new submission for OTC?06:45 – Implications of removing the healthcare provider from the equation12:00 – Risk management: Expanding risk profiles when lay users are involved18:15 – When a 510(k) becomes a De Novo or PMA22:50 – Usability testing and the risk of user error in OTC devices31:20 – Clinical investigations and good clinical practices (GCPs)36:00 – Real-world evidence vs. real-world data—what's usable?41:30 – Using Pre-Subs effectively and what “quality data” really means47:10 – Labeling, cleaning, and UDI for OTC products53:40 – OTC software and digital health—when is it a regulated device?01:00:00 – Summary: Aligning regulatory logic with common sense and business strategyQuotes“With an OTC device, we are taking the healthcare professional totally, completely, and utterly out of the loop.”– Mike DruesThis quote encapsulates the core regulatory challenge in moving a device to OTC: every element, from labeling to usability, must assume zero clinical supervision.“If the clinical trial won't tell you anything you don't already know from good real-world evidence, why spend the time and money?”– Mike DruesA powerful argument for using well-documented real-world evidence over unnecessary trials—provided the data truly meets evidentiary standards.Top TakeawaysLabel Expansion ≠ Shortcut: Moving from prescription to OTC usually requires a new submission—especially when removing the healthcare provider introduces new risks.Usability Testing Is Critical: OTC usability studies must go beyond IFU comprehension to include risk of misuse, poor device selection, and user decision-making.Real-World Evidence Can Help—If It's Clean: Real-world data isn't always usable. FDA will expect reproducibility, traceability, and strong justifications.Labeling & Design Must Assume No Clinical Oversight: Cleaning procedures, warnings, and directions must all be validated for home use and layperson comprehension.Use Pre-Subs Wisely: Especially for label expansions or gray-area digital health tools, pre-subs provide critical alignment with FDA and prevent costly errors.References & ResourcesEtienne Nichols on LinkedInFDA Guidance on Real-World Evidence for Regulatory Decision-MakingGreenlight Guru Webinar: What is and Isn't a Regulated Medical Device (feat. Mike Drues)FDA Guidance: Clinical Decision Support SoftwareMedTech 101: OTC vs Prescription DevicesAnalogy: Think of prescription vs. OTC devices like driving a manual vs. automatic car. Prescription devices assume a trained “driver” (the healthcare provider), while OTC devices must be intuitive and safe enough for anyone to “drive”...

Episode 299 hosts Dr Darryl Reed (Biochemist & COO of Tissue Repair from Sydney, Australia) and Charlotte Meli (Registered Nurse and NSW Territory Manager of Tissue Repair from Sydney, Australia) In this episode we learn about Tissue Repair and their unique product TR Pro +. This novel hydrogel product contains beta-glucans (a derivative from yeast) and has been clincically proven and is TGA-approved to help wound healing.  We find out who Tissue Repair are, the science behind TR Pro + and how this can be applied in aesthetic practices. This podcast was supported by Tissue Repair 00:30 Introduction  00:42 Our Upcoming 300th Podcast and IA Competition 02:01 Introducing Tissue Repair and TR Pro +  02:23 Darryl Reed's Journey into Aesthetics  04:10 Charlotte Meli's Background and Role  05:18 The Origins and Development of TR Pro +  07:41 Understanding Beta Glucans and Their Benefits  16:19 TGA Approval and Market Expansion  18:01 Clinical Studies and Real-World Evidence  22:18 Versatility and Benefits of TR Pro +  22:50 Clinical Feedback and Usage  23:35 Post-Injectable Applications  24:33 Science Behind the Semi-Permeable Film  25:15 Contraindications and Safety  27:38 Anti-Itching and Inflammation Control  29:04 Scar Treatment and Healing  30:17 Product Availability and Pricing  37:13 Future Developments and Applications  41:13 Conclusions and Final Thoughts READ THIS GUIDE TO JOIN OUR PATREON AS A FREE MEMBER OR SUBSCRIBE TO OUR PATREON FOR EXCLUSIVE PODCASTS, WEEKLY EDUCATIONAL CONTENT & JOIN OUR WHATSAPP COMMUNITY CLICK HERE TO BROWSE OUR IA OFFERS FOR DISCOUNTS & SPECIALS CLICK HERE IF YOU'RE A BRAND OR COMPANY & WANT TO WORK WITH US CLICK HERE TO APPLY TO BE A GUEST ON OUR PODCAST CONTACT US

Christine Verini is a pharmacist by training, a nonprofit CEO by title, and an unapologetic empath by design. She now leads CancerCare, one of the oldest, least-known, and most impactful organizations in the country that actually helps real cancer patients deal with the practical garbage no one likes to talk about—like paying rent, affording a ride to chemo, or feeding their kids.We talk about her career pivot from industry to impact, what it's like trying to scale empathy without losing your soul, and the daily gut-punch of knowing there are millions of people who still have no idea that CancerCare exists. Christine gets real about leadership, advocacy, burnout, and why being “pan-cancer” matters more than ever in a world obsessed with biomarkers, buckets, and branding.She also dishes on what AI gets dead wrong, what patients actually want when they call for help, and why “ghosting” someone with cancer is still a thing. Buckle up. This one's packed with heart, brains, and a little righteous rage.RELATED LINKSCancerCareChristine Verini on LinkedInChristine's CEO Announcement – PR NewswireCancer Health 25: Christine VeriniChristine on HealthyWomenBIO Convention Speaker ProfileFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The potential for real world evidence (RWE) is huge, according to enthusiasts, but to the uninitiated it can seem like a complicated and forbidding subject. In this Over the Counter double episode, IQVIA Consumer Health's vice president of global research and development and real-world evidence services, Volker Spitzer, makes understanding real world evidence easy. We start with the basics, with what it is and what companies need to know about it, and what the key difference is with randomised control trials. Many companies are already using real world evidence, Volker notes, and he extracts some key lessons for companies interested in trying it out based on his extensive experience working with industry on such projects. Timestamps 2:00 – Introductions 4:00 – What is real world evidence? 5:00 – Can RWE and clinical trials complement each other? 10:00 – Why RWE is particularly attractive today 14:00 – Don't reinvent the wheel 18:00 – Why is this important for consumer health companies? 25:00 – Why RWE is often a good value option, especially for SMEs 33:00 – Applications of RWE in consumer health Guest Bio Volker Spitzer has more than 30 years of R&D experience spanning the consumer health sector, ingredients industry, and academia. Beginning his career as a professor in pharmaceutical sciences, he ascended to global positions encompassing R&D, innovation, licensing/M&A, and medical marketing at firms like Roche, DSM Nutritional Products, and Bayer. Since October 2017, Volker has been affiliated with IQVIA Consumer Health, serving as the vice president for global R&D and RWE Services. His purview primarily includes clinical research, RWE, virtual trials, and the burgeoning field of digital health. He has penned over 80 scientific publications, whitepapers and textbooks centered on science and innovation.

Jennifer Finkelstein is not here for your pity, your pinkwashed slogans, or your performative awareness campaigns. She's a 20-year young adult breast cancer survivor who turned trauma into a blueprint for action and built 5 Under 40, a no-BS nonprofit supporting women diagnosed with breast cancer under 40.In this episode, we go full Gen X therapy session—from SNL nostalgia and cold caps to the absurdity of finding out you have cancer while looking for the remote. Jen drops real talk about founding a nonprofit when nothing existed for her age group, why mental health support isn't optional, and how passing down designer scarves can mean arming someone for battle.If you're looking for honesty, grit, and a few inappropriate jokes about gastroenterology, this one's for you. You'll laugh, you might cry, and you'll definitely leave knowing why Jennifer Finkelstein is a survivor, a fighter, and a damn legend.RELATED LINKS5 Under 40 FoundationJennifer Finkelstein on LinkedInAbout 5 Under 40: Board of DirectorsDan's Papers: 5 Under 40 Supports Young Breast Cancer SurvivorsFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.Let me know if you want shorter pull quotes, audiogram text, or promotional copy for LinkedIn, Instagram, or your newsletter.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What happens when a black belt, sword-slinging fitness icon gets cancer—twice? She picks up a camera and dares the universe to test her again.Ilaria Montagnani is not your average anything. She's been building strong bodies (and stronger minds) for over 30 years as the founder of Powerstrike. She's part Jane Fonda, part Uma Thurman, and very much the action hero you wish was your personal trainer.In this episode, we talk about what happens when everything you built your life on—movement, strength, purpose—gets sideswiped by disease. Twice. Ilaria opens up about diagnosis shock, bad doctor vibes, wielding swords post-mastectomy, and why working out through treatment is the best revenge.We get into scanxiety, menopause side effects, nutrition spirals, and the moment she realized the fitness industry needed more truth—and less bullshit.This one's real, raw, and will either guilt you into planking or inspire you to finally cancel that gym membership you've never used. Either way, you're gonna feel something.RELATED LINKSStronger for Life documentaryPowerstrike official siteIlaria on InstagramIlaria on LinkedInWorkout programs and DVDsForza Sword Workout on AmazonFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Helene M. Epstein is not here to make friends with the healthcare system. She's here to dismantle the bullshit, one catastrophic medical error at a time. A marketing agency veteran turned patient safety firebrand, Helene's journey from copywriter to cancer misdiagnosis survivor, to “badass queen of patient safety,” is one hell of a ride.We talk about how her son was misdiagnosed over 15 times (yes, really), why some doctors should come with warning labels, and how American healthcare gaslights patients like it's a competitive sport. She also explains why she's giving away her new book for free, one chapter at a time, and how AI might actually be useful—if it stops hallucinating citations.This is not a light listen. It's the real deal. You'll walk away angry, inspired, and a lot more dangerous as a patient.RELATED LINKSHelene's Substack: https://helenemepstein.substack.comPatient Safety Resources: https://www.pfps.usSociety to Improve Diagnosis in Medicine: https://psnet.ahrq.gov/issue/society-improve-diagnosis-medicineHelene's Website: https://www.hmepstein.com/meet-heleneLinkedIn: https://www.linkedin.com/in/hmepsteinFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform.For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jonathan and Jennifer Wall didn't choose this path, but they're walking it with purpose. After losing their son, Zach, they turned their grief into action, founding Zach's Bridge, a lifeline for families navigating pediatric cancer. This episode isn't about platitudes or silver linings—it's about the raw, unfiltered reality of love and loss, the relentless unfairness of childhood cancer, and how the Walls are refusing to let their son's memory fade into the void.Jon and Jenn open up about what Zach taught them, how they've reshaped their lives in his honor, and why “Be Like Zach” isn't just a phrase—it's a call to action. We talk about the power of community, the frustrating gaps in pediatric cancer care, and how they're making sure no other family has to walk this road alone. If you've ever wondered what real resilience looks like, this is it.RELATED LINKS:Zach's BridgeZach's Rules for LifeBe Like Zach - SubstackJonathan Wall on LinkedInJon's Post: What Cancer Taught Me About WorkRett's Roost Blog - Jonathan's WritingZach's Story - OSIFEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Sarah Armstrong—forever Sarah Oakden to me, no matter what the legal documents say—isn't just my best friend. She's my first college friend, my musical theater soulmate, and the first person who truly saw me as an artist. She was there when I walked onto Binghamton's campus, and she was there when I walked into cancer hell. And, because we're nothing if not in sync, a few decades later, she got her own cancer badge of honor, and I was right there with her every step of the way.This episode is a love letter to friendship, music, and those moments that change your life forever. We nerd out over Sondheim, Binghamton's infamous "Theater 101 with Dr. Susan Peters." and the weird and wonderful rabbit holes that turn into entire alternate realities across decades of aging gracefully and falling with style.We talk about how cancer is the worst club with the best people and how surviving it together just adds another verse to the song we've been singing for 30 years. It's funny. It's real. It's a master class in love, laughter, and musicals that should have been bigger; with a big tip of the hat to Nancy Ford and Gretchen Cryer for their acclaimed musical "I'm Getting My Act Together and Taking It on the Road"Oh, and RIP to the legendary Denny's on Vestal Parkway. You will be missed.FEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Food for Thought: Cancer, Calories, and Kicking AssVanessa Rissetto is back, and she's bringing the same energy, wit, and unapologetic realness that made her a fan favorite. Last time, we talked nutrition and the rise of Culina Health. This time, life threw her a plot twist—breast cancer. Because, you know, irony.Vanessa was busy building a nutrition empire when she got diagnosed. So, naturally, she texted, “WTF do I do now?” to her closest cancer Sherpas—yours truly included. Spoiler alert: She powered through, beat cancer, and kept scaling Culina Health to new heights.We get into it all—being a cancer patient when you're supposed to be the health expert, the emotional whiplash of survivorship, the absolute clown show that is American food regulation, and why European Oreos are apparently less cancerous than ours. Also, parenting, loneliness, and why the healthcare system still makes zero sense.Get ready for a wild ride of truth bombs, wisdom, and laughter with one of the sharpest voices in nutrition and entrepreneurship.RELATED LINKSVanessa on LinkedInCulina HealthVanessa's WebsiteVanessa's Story on HLTHVanessa on Breast Cancer - TODAYWhat Vanessa Learned About Food After CancerDaily Mail: Vanessa on an Unexpected SymptomSurvivorNet: Vanessa on Nutrition and CancerFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

EPISODE DESCRIPTIONLillian Kreppel doesn't hold back. A seven-year anal cancer survivor and co-founder of the HPV Cancers Alliance, she has made it her mission to challenge stigma, fight misinformation, and push for better awareness of HPV-related cancers. In this episode, she sits down with Matthew Zachary to talk about her journey from high-powered sales to full-time advocacy, the absurd misconceptions surrounding HPV, and why more doctors should be doing rectal exams—but aren't. With her signature humor and relentless drive, Lillian shares how she turned her diagnosis into a movement, what it takes to make people uncomfortable for the right reasons, and why she refuses to stop talking about the HPV vaccine. It's an eye-opening, unfiltered, and surprisingly hilarious conversation about a serious issue too many people ignore.RELATED LINKSHPV Cancers Alliance: https://hpvca.org/Lillian's Story (MSKCC): https://www.mskcc.org/experience/hear-from-patients/lillianInterview on HPVWorld: https://www.hpvworld.com/articles/anal-cancer-and-hpv-a-history-of-awareness-and-stigma-interview-with-lillian-kreppel/Speaking With Lillian Kreppel (Ask About HPV): https://www.askabouthpv.org/stories/speaking-with-lillian-kreppel-co-founder-of-the-hpv-cancers-allianceEuropean Cancer Organization Feature: https://www.europeancancer.org/content/lillian-kreppel.htmlAnal Cancer Survivor Feature (Patient Resource):https://www.patientresource.com/Anal_Cancer_Survivor_Lillian_KreppelFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Grace Charrier—a powerhouse advocate, author, and cancer survivor—whose journey from a Stage 3 triple-negative breast cancer diagnosis to global advocacy is nothing short of extraordinary. Originally from Nigeria, Grace's life was upended when she was diagnosed following an unexpected health scare. Instead of retreating, she turned her experience into action, launching Cancer Convos with Grace B, writing the memoir IMPOSSICANT!, and becoming a voice for patients navigating the complexities of cancer care worldwide.Matthew and Grace dive into the realities of living with cancer, from the absurdities of the U.S. healthcare system to the deeply ingrained stigmas surrounding the disease in Africa. They explore the critical role of doctor empathy, the perils of consulting “Dr. Google,” and the relentless frustration of dealing with insurance providers. The conversation is raw, unfiltered, and filled with humor, as they trade stories about survivorship, advocacy, and the power of storytelling in making sense of the chaos.This episode delivers a mix of inspiration, honesty, and irreverence—showcasing Grace's unwavering determination to change the cancer narrative, one conversation at a time.RELATED LINKS:Grace Charrier on LinkedInCancer Convos with Grace B on YouTubeGrace's Memoir: IMPOSSICANT! on AmazonBlue Note TherapeuticsRare Patient VoiceImerman AngelsAmerican Cancer Society Cancer Action NetworkRed Door CommunityHealth UnionAdvocates for Collaborative EducationFEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Buckle up, because Amy Gittelman is back, and this episode is one for the ages. A fellow SUNY Binghamton (yes, we still call it that) alum, Amy joins me for a hilarious and brutally honest deep dive into the absurdities of healthcare, insurance fuckery, and the general nonsense that plagues the system. From dodging medical debt landmines to battling insurance companies that seem hellbent on denying care, we go all in.But wait—there's more! We reminisce about our Binghamton days, debate the superiority of Wegmans over every downstate grocery store, and expose the dark art of healthcare billing fraud (spoiler: it's as bad as you think). Amy, a seasoned healthcare badass, drops wisdom bombs on why the industry is broken, what we can do about it, and why she's basically a mix of Miranda Priestly, Leslie Knope, and Dolly freakin' Parton.If you've ever yelled at your insurance company, fought a medical bill, or just wanted to flip a table over the state of American healthcare, this episode is for you.RELATED LINKS:Amy Gittelman on LinkedInAmy's Odyssey Feature on PM360Amy's Profile on OncoDailyVeradigm Healthcare SolutionsFEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Welcome to another episode of Out of Patients, where we get real about the absolute circus that is the American healthcare system. If you've ever been trapped in a medical billing nightmare, gaslit by insurance reps, or just generally felt like healthcare is an elaborate game designed to screw you—this one's for you.Joining me is the indomitable Deb Gordon, a relentless champion for healthcare consumers, co-founder of Umbra Health Advocacy, and co-director of the Alliance of Professional Health Advocates. She literally wrote the book (The Healthcare Consumer's Manifesto) on navigating this broken system—and she's here to help you get unf*cked.We talk about why the healthcare system is a hot mess, how patient advocacy is (unfortunately) a booming business, and why you shouldn't have to fight tooth and nail just to get the care you're entitled to. And yes, there are people you can hire to help you navigate the bureaucratic hellscape of prior authorizations, medical bills, and misdiagnoses. It's an infuriating conversation—but also wildly empowering.If you've ever thought, Where the hell was this when I needed it?—well, now you know.RELATED LINKS

You know how some people enter your life with a knock, a bang, or maybe even a LinkedIn request? Not Rebecca Batterman, returning champion to Out of Patients, making her dramatic second appearance,Back in 2019, she karmically appeared like a plot twist in a film noir—unexpected, inevitable, and full of surprises. An AI strategist, an optimist (yes, those exist), and a young adult cancer survivor, Rebecca is here to school us on everything from the future of AI in healthcare to why nostalgia is a coping mechanism we all need. In this no-BS conversation, we talk about the state of innovation (is it still a buzzword?), the wild advancements in early cancer detection, and whether AI-generated empathy is just another overpromised tech fantasy.We also take a detour into the absurdity of pinkwashed cancer fundraising, the evolution of cancer portrayals in pop culture, and the ultimate question: Can you separate the art from the artist? Come for the cancer survivorship insights, stay for the South Park references and existential musings on whether you'd rather live in the past (with no antibiotics) or the future (with AI clones of yourself). RELATED LINKSRebecca Batterman on LinkedInUnderstanding AI on MavenRebecca's Articles on AdweekBreast Positivity as Self-CareFEEDBACKLike this episode? Rate and review *Out of Patients* on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Tricia Brouk isn't just a storyteller—she's a story architect, crafting narratives that connect humanity. A former ballet dancer turned award-winning director, choreographer, and transformational speaker coach, Tricia brings her unique journey to the mic in this captivating conversation. From dancing in iconic opera houses to choreographing Hollywood blockbusters, she has mastered the art of turning moments into movements.In this episode, Tricia and I dive deep into the magic of storytelling as a service, the difference between telling a story and truly captivating an audience, and how vulnerability can transform lives. Whether you're looking to step into the spotlight or just understand how to leave a meaningful legacy, Tricia's insights will challenge and inspire. Plus, don't miss her tales of collaborating with icons like James Gandolfini and Susan Sarandon, and her hilarious take on 80s nostalgia.Hit play and discover why Tricia Brouk is the influential voice you didn't know you needed.RELATED LINKS:Tricia Brouk's WebsiteTricia's Book: The Influential VoiceLinkedIn ProfileThe Big Talk PodcastFEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready for a wild ride with Matt Lewis, the Tony Stark-meets-Jerry Seinfeld of the mental health AI world. As a multi-degreed polymath, Matt has been ahead of the curve on AI since MySpace was a thing. In this episode, we dive into everything from neuroethics and AI-powered mental health solutions to existential fears of Skynet ruining your day. Matt shares the real scoop on how AI can revolutionize diagnosis, therapy, and even the very definition of sanity—while hilariously lamenting the difficulty of spelling “rhythm.” If you've ever wondered whether AI is here to save the world or just mess with your playlist, this episode is for you. Join us as we balance hope, skepticism, and an unhealthy number of 80s references in this thought-provoking, laugh-out-loud conversation.RELATED LINKSMatt Lewis on LinkedInLLMental Official WebsiteMatt's Feature on MM+M OnlineFEEDBACKLike this episode? Rate and review *Out of Patients* on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What happens when you give a 14-year-old the mic and let her fly solo without her twin brother? Magic, that's what. This episode of Out of Patients features my daughter, Hannah, on her seventh (yes, seventh) appearance on the show, but this time she's stealing the spotlight solo. From reminiscing about slushy Christmas Eves and rare baby illnesses to deep dives into the hexagonal perfection of honeycombs, this mini-episode is packed with wit, banter, and a healthy dose of dad jokes. We touch on everything from gaming nostalgia to family quirks, proving once again that sometimes the best conversations happen when you just press record. Whether you're a longtime listener of the Zachary family chronicles or new to the Out of Patients universe, this one's got laughs, lessons, and a little love for everyone.FeedbackLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Prepare for a whirlwind of brilliance with Dr. Natanya Wachtel—a self-proclaimed "failed therapist" turned media maven, behavioral strategist, and all-around badass. In this episode, we dive into her transformative journey from navigating personal loss to spearheading innovative mental health initiatives and reimagining her own identity in a world that loves labels. From her esoteric love of theater and eclectic career in Big Pharma to candid insights about obesity, Ozempic, and the not-so-great healthcare system, Natanya delivers an unfiltered look at life's complexities with humor and heart.Expect laughs, life lessons, and a few "did-they-really-just-say-that" moments as we explore why it's okay to be a hot mess—and how embracing it can lead to your most authentic self. This is not just an episode; it's an experience. Buckle up.RELATED LINKS:Dr. Natanya Wachtel's WebsiteDr. Natanya Wachtel on LinkedInDr. Natanya Wachtel on Marquis Who's WhoDr. Natanya Wachtel on World's LeadersFEEDBACK:Like this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Back for Round 2 and wielding her wit like a machete, Jen Singer returns to Out of Patients with Matthew Zachary. Cancer survivor, heart failure "graduate," and creator of the 'Just Diagnosed Guides,' Jen has seen it all — and she's here to help YOU see it all more clearly. From dismantling medical jargon to calling BS on "Stay Strong" toxic positivity, this conversation is a masterclass in how to survive, thrive, and laugh in the face of life's curveballs. Need a guide on what to do the day sh*t hits the fan? Jen wrote it. Need permission to be pissed off? She grants it. From 'elegant tumors' to 'unremarkable tests' (the best kind), this episode is a hilarious, human, and wholly unfiltered look at the realities of being sick in America. You'll laugh, you'll learn, and you'll definitely Google 'heart boo-boo.'RELATED LINKS:Jen Singer's WebsiteAbout Jen Singer - Just Diagnosed GuidesJust Diagnosed GuidesJen's LinkedInJust Diagnosed Guide on National Breast Cancer FoundationEpisode 269: Jen Singer on Out of Patients (2022)FEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Prepare to be inspired and entertained as Sean Wachter returns to Out of Patients! Sean, aka "The Cancer Fighter," is a two-time melanoma survivor, professional wrestler, coffee shop entrepreneur, and self-proclaimed 'f**ked up Forrest Gump.' With a resume that includes Madison Square Garden, WWE dreams, and a 'We Got This' People's Champion belt, Sean's journey of triumph over cancer (and doctors who didn't believe him) is nothing short of extraordinary. This episode dives into Sean's fight against misdiagnosis, his wrestling odyssey, and his hilarious philosophy of not having “time for why.” Get ready for a rollercoaster of grit, humor, and inspiration, capped with a dose of 80s nostalgia and a no-holds-barred approach to life.RELATED LINKSSean Wachter's Instagram: @thecancerfighterseanwachterSean Wachter on LinkedIn: Sean WachterOvercoming Brain Mets and LMD: Sean's Melanoma Journey: Cure Melanoma Blog"Live and Live Fully" Story: V FoundationFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this lively and insightful episode of Out of Patients, host Matthew Zachary sits down with Mariana Arnaut, Founder and CEO of The After Cancer, a groundbreaking platform helping cancer survivors navigate the uncharted waters of life post-treatment. Joined by his sharp and witty Chief of Staff, Jen Ramprasad, the trio dives into the gaps in survivorship care, the rise of "cancer retail," and the moral dilemmas of monetizing support services for the cancer community. Mariana also shares the story behind Cards Against Cancer, a clever spin on the popular party game that has sparked meaningful—and sometimes hilarious—conversations within the cancer survivor community. From the challenges of living in Portugal to the wild world of U.S. healthcare, this episode is a mix of humor, humanity, and hard truths.RELATED LINKSThe After CancerCancerConAmerican Cancer Society's Report on Survivorship CostsConnect with Mariana ArnautFEEDBACKLike this episode? Rate and review *Out of Patients* on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What happens when two fresh-faced Gen Zers—Matthew Zachary Worldwide Chief of Staff Jenisa Ramprasad and Marketing Intern Lauren Woodring—sit down with a cranky, nostalgia-fueled Gen Xer (ahem, Matthew Zachary)? Chaos, hilarity, and surprisingly deep insights.This is not your typical Out of Patients episode.What started as a casual, unscripted chat turned into a generational therapy session touching on everything from floppy disks, cassette tapes, and AOL chat rooms to TikTok-induced existential crises and frenetic media consumption with no "ohio baby gronk rizz" or "skibidi toilets". (Whatever that means)Why are Gen Zs so quick to cut off friends? Can you really form deep bonds with someone you've never met in person? And what was the deal with Blu-rays anyway? (Thank you, Producer Kyle Moore, for your added insights) We tackled all the questions, shared plenty of laughs (awkward and intentional), and even found common ground in our shared love for real, human connection. If you've ever felt caught between the "back in my day" crowd and the "why does everything move so slow?" generation, this episode is for you. Prepare to channel your inner dope/phat/fresh inner teenager while cringing to pop culture mansplaining, and maybe even feel inspired to unplug for a minute (but only after you finish listening, of course).RELATED LINKSJenisa Ramprasad on LinkedInLauren Woodring on LinkedInSUNY Binghamton UniversityFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It's the annual Out of Patients tradition you didn't know you needed—Matthew's miracle IVF twins, Koby and Hannah, are back on the mic for their 5th appearance! These famous 14.5-year-old personalities are here to make you laugh, reflect, and maybe even sing the alphabet incorrectly (spoiler: they hate the new version). Dive into a delightful blend of sibling banter, high school stories, Broadway show recaps, and unexpected eyebrow-shaving anecdotes. Whether it's Koby's law class revelations or Hannah's set design dreams, this episode captures the chaos, charm, and brilliance of two teens navigating life—and making their dad immensely proud. Prepare for laughter, nostalgia, and some genuine moments of gratitude that will leave you smiling. So, tune in for the podcast episode, which is as much a gift to listeners as it is to the proudest dad in podcasting!FEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

When life hands you a cancer diagnosis, you grab a camera. Anna and Jordan Rathkopf turned their battle with HER2-positive breast cancer into a groundbreaking photojournalistic journey. Join Matthew Zachary as he chats with the Rathkopfs about their book, HER2: The Diagnosed, The Caregiver, and Their Son, their nonprofit work, and the absurdity of pink-washed cancer campaigns. It's a raw, funny, and heartfelt discussion about navigating illness, caregiving, and the power of authenticity in art and life.RELATED LINKSAnna Rathkopf on LinkedInJordan Rathkopf on LinkedInDaylight BooksUpcoming Exhibitions: Check out their nonprofit work at PCAC.ngo.FEEDBACKLike this episode? Rate and review *Out of Patients* on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this full-circle conversation, Matthew Zachary sits down with Amy Sutton, Executive Director of Crossroads4Hope, to dive deep into the evolution of cancer support and the profound legacy of organizations like the Wellness Community. From reminiscing about pre-internet cancer advocacy to envisioning a future rooted in public health and equity, this episode explores the human side of care in ways only Matthew can deliver—with wit, humor, and an unfiltered lens.Amy shares her journey from working at Rand McNally (yes, the map company) to becoming a torchbearer for cancer patients, caregivers, and survivors. They tackle everything from the challenges of sustaining local cancer support services in a digital-first world to how the healthcare system neglects the psychosocial needs of both patients and caregivers. Together, they unpack the crucial role of social workers, the necessity of caregiver inclusion, and why navigating life post-cancer diagnosis demands more than just clinical solutions.Whether you're a cancer survivor, caregiver, healthcare professional, or just someone trying to make sense of this messy world, this episode promises insights, laughs, and plenty of Gen X nostalgia. Plus, find out why Matthew thinks we should stock up on Rand McNally maps for the apocalypse.Be sure to check out Crossroads4Hope's groundbreaking Professional Development Conference in March 2025, where Matthew will be the keynote speaker. More details at MatthewZachary.com/C4H.RELATED LINKSCrossroads4Hope WebsiteAbout Amy SuttonFEEDBACKLike this episode? Rate and review *Out of Patients* on your favorite podcast platform. For guest suggestions or sponsorship inquiries, email podcast@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.