The composite of the organism's observable characteristics or traits
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9 episodes with phenotypes
6 episodes with phenotypes
8 episodes with phenotypes
5 episodes with phenotypes
3 episodes with phenotypes
4 episodes with phenotypes
4 episodes with phenotypes
3 episodes with phenotypes
17 episodes with phenotypes
Commentary by Dr. Jian'an Wang.
Jay Gunkelman goes in BLIND on Case 9 — an 18-year-old's eyes-open EEG, age only, no history. Joshua Moore bet his car on a left posterior concussion. Jay sees something deeper: a thalamocortical dysrhythmia at the anterior cingulate, slow and fast rhythms coupled together, beta spindling above 30 Hz that most databases can't even see. Left-side mu disconnect shutting down the language hemisphere. Posterior insula, left side. After half a million EEGs, Jay's verdict isn't a diagnosis — it's a phenotype that tells you how to treat it, not what to call it.
Commentary by Dr. Leandra Serio.
Broadcast from KSQD, Santa Cruz on 4-30-2026:>/p> Dr. Dawn opens with a bike safety public service message, noting a 34% increase in bicycle use in Santa Cruz alongside rising e-bike accidents. She urges drivers to stay vigilant and calls for education and enforcement of helmet laws, particularly for riders under 18. A University of Michigan researcher discovered that standard nitrile, latex, and vinyl gloves shed stearate particles indistinguishable from polyethylene under spectroscopy, contaminating microplastics research with approximately 2,000 false positives per square millimeter. Only clean-room gloves avoided this problem, throwing years of microplastics studies into question. Dr. Dawn explains skin's three-layer structure and the stratum corneum's ceramide-based moisture barrier. She warns against stripping natural oils with astringents and hot showers, notes that UV disrupts proteins holding skin cells together, and cites a 2019 study showing moisturing treatment reduced circulating inflammatory cytokines in older adults. Making music coordinates sound, vision, motor control, and imagination across the brain. Studies show musicians have more gray matter, better executive function, sharper memory, and even reduced pain sensitivity. A 2010 paper found musicians who began before age seven have a larger corpus callosum, and a 2024 study showed pianists had better working memory while woodwind players did best at executive function. Stanford researcher Pascal Geldsetzer analyzed populations in Australia, New Zealand, Wales, and Ontario, finding the Shingrix vaccine reduces dementia risk by up to 20%. Dr. Dawn hypothesizes that even "dormant" varicella triggers low-level inflammation affecting brain microglia, and recommends spacing Shingrix three months apart from the second dose rather than one month to avoid side effects. A Nature study of 175 people watching movies found that observing someone being touched activates the same brain regions as being touched yourself—your brain experiences sensations in corresponding body parts. This vision-touch link could enable less invasive sensory testing for autistic individuals. Princeton and Flatiron Institute researchers identified four distinct autism phenotypes: broadly affected (10%), mixed with developmental delay (19%), moderate challenges (33%), and social/behavioral (37%). A second Nature study confirmed genetically distinct forms unfold on different timelines, with post-age-six diagnoses showing different genetic profiles than early childhood cases.
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Commentary by Dr. Jian'an Wang.
In this podcast, Sarah Horton discusses her paper 'Developmental stuttering with common and complex phenotypes'. The paper is available here: https://doi.org/10.1111/dmcn.70208 Follow DMCN on Podbean for more: https://dmcn.podbean.com/ ___ Watch DMCN Podcasts on YouTube: https://bit.ly/2ONCYiC __ DMCN Journal: Developmental Medicine & Child Neurology (DMCN) has defined the field of paediatric neurology and childhood-onset neurodisability for over 60 years. DMCN disseminates the latest clinical research results globally to enhance the care and improve the lives of disabled children and their families. DMCN Journal - https://onlinelibrary.wiley.com/journal/14698749 ___ Find us on Twitter! @mackeithpress - https://twitter.com/mackeithpress
Send a textNatasha is a registered physical therapist with more than a decade of clinical experience. She holds degrees in Health Science and Kinesiology, along with a Master's in Physical Therapy from the University of British Columbia. Over the course of her career, she has developed specialised expertise in concussion recovery, neurological rehabilitation, chronic pain management, vestibular therapy, and functional neurology. She is the founder of Symphony Brain Performance, a clinic that has become a sought-after destination for individuals seeking specialised care for concussion and brain health. Natasha's innovative work has earned significant recognition, including Canada's Entrepreneur of the Year Award, the Physiotherapist Leadership Award of British Columbia, and Vancouver Island's Top 20 Under 40 Business and Community Achievement Award. She has also recently been nominated for the Women of Influence Award. In addition to her clinical work, Natasha is the founder and host of the Concussion Nerds podcast and program, where she shares insights and conversations focused on brain health, concussion recovery, and performance. 01:35 - How Natasha Become a Physical Therapist05:30 - Integration into Concussion Rehabilitation 12:50 - What is a Concussion?16:40 - What are the Phenotypes of Concussion? 22:00 - Approach in Treating Concussion/ Misconceptions30:00 – Psychology and Terminology of Concussion37:35 – Myths Around Concussion42:55 – Rewards of Natasha's Job44:30 - Where Can People Find Concussion Nerds and Natasha Concussion Nerds – Natasha Wilch https://www.natasha-wilch.com/concussion-nerdsPodcast: The Concussion Nerds Podcast – Spotify/ Apple Facebook: https://www.facebook.com/natasha.wilch.concussioncoach/ IG: @natash.wilch & @concussionnerds YouTube:@NatashaWilch-ConcussionNerdSubscribe, review and share for new episodes which will drop fortnightly Social media:Twitter: @first concussionFacebook: Headfirst: A concussion podcastInstagram: Headfirst_ Concussion Email: headfirstconcussion@gmail.com
Join Professor Laura Coates and Phillip Mease as they discuss the top publications in the world of PsA. This month, the conversation covered the ‘classification of patients into distinct PsA phenotypes based on baseline demographics and clinical characteristics using a machine learning approach, and consensus-derived GRAPPA terminology, to support shared clinical decision making, and enable more effective patient stratification in both observational studies and clinical trials.
In the second installment of this two-part series, Drs. Stacey Clardy, Ayush Gupta, and Kuntal Sen discuss the most practical testing approach to minimize both under‑ and over‑testing for these disorders. Show citation: Gupta A, Sahjwani D, Kahn I, Gombolay GY, Sen K. Monogenic Mimics of Neuroinflammatory Phenotypes in Children and Young Adults: An Evolving Landscape. Neurol Genet. 2025;11(6):e200326. Published 2025 Nov 25. doi:10.1212/NXG.0000000000200326 Show transcript: Dr. Stacey Clardy: Hi, this is Stacey Clardy from the Salt Lake City VA in the University of Utah. For a two-part podcast series this week, I've been speaking with Ayush Gupta, from the University of Nebraska Medical Center, and Kuntal Sen, from Children's National Hospital in Washington, DC about monogenic disorders that mimic neuroinflammatory disease. There are a lot of them, and they are no doubt sitting in our clinics waiting to be recognized. Ayush, for the minute, once a neurologist starts suspecting one of these disorders, what's the most practical testing strategy to avoid both under and over-testing for these disorders? Dr. Ayush Gupta: I think the most practical strategy is to write down all the phenotypic symptoms that you think could be related, put that exact information into a genetic testing panel that will be suitable. Or, if possible, try to do a broader genetic testing such as whole genome sequencing, and make yourself equipped to be able to analyze the results that you get from the testing. Dr. Stacey Clardy: I hear you saying, at least when you're thinking about this, be a bit of a lumper. As we covered in the podcast, if we are going to pursue that genetic testing, it is absolutely critical that we share that list with the interpreting geneticist because that determines how they score variants and how they rate them as related or not. Please take a listen to that two-part podcast series, where we get into all these details. I walked away with a great framework on how to do better in terms of picking these disorders out. Again, the paper that accompanies the two-part podcast series is in Neurology Genetics. It's a comprehensive review and called Monogenic Mimics of Neuroinflammatory Phenotypes in Children and Young Adults in Evolving Landscape. Thank you, Ayush. Dr. Ayush Gupta: Thank you so much.
In the second installment of this two-part series, Drs. Stacey Clardy, Ayush Gupta, and Kuntal Sen discuss the most practical testing approach to minimize both under‑ and over‑testing for these disorders. Show citation: Gupta A, Sahjwani D, Kahn I, Gombolay GY, Sen K. Monogenic Mimics of Neuroinflammatory Phenotypes in Children and Young Adults: An Evolving Landscape. Neurol Genet. 2025;11(6):e200326. Published 2025 Nov 25. doi:10.1212/NXG.0000000000200326 Show transcript: Dr. Stacey Clardy: Hi, this is Stacey Clardy from the Salt Lake City VA in the University of Utah. For a two-part podcast series this week, I've been speaking with Ayush Gupta, from the University of Nebraska Medical Center, and Kuntal Sen, from Children's National Hospital in Washington, DC about monogenic disorders that mimic neuroinflammatory disease. There are a lot of them, and they are no doubt sitting in our clinics waiting to be recognized. Ayush, for the minute, once a neurologist starts suspecting one of these disorders, what's the most practical testing strategy to avoid both under and over-testing for these disorders? Dr. Ayush Gupta: I think the most practical strategy is to write down all the phenotypic symptoms that you think could be related, put that exact information into a genetic testing panel that will be suitable. Or, if possible, try to do a broader genetic testing such as whole genome sequencing, and make yourself equipped to be able to analyze the results that you get from the testing. Dr. Stacey Clardy: I hear you saying, at least when you're thinking about this, be a bit of a lumper. As we covered in the podcast, if we are going to pursue that genetic testing, it is absolutely critical that we share that list with the interpreting geneticist because that determines how they score variants and how they rate them as related or not. Please take a listen to that two-part podcast series, where we get into all these details. I walked away with a great framework on how to do better in terms of picking these disorders out. Again, the paper that accompanies the two-part podcast series is in Neurology Genetics. It's a comprehensive review and called Monogenic Mimics of Neuroinflammatory Phenotypes in Children and Young Adults in Evolving Landscape. Thank you, Ayush. Dr. Ayush Gupta: Thank you so much.
On this episode of The Digital Patient, Dr. Joshua Liu, Co-founder & CEO of SeamlessMD, and colleague, Alan Sardana, chat with Dr. Priti Patel, CMIO at John Muir Health, about "Phenotypes of Clinician AI Adopters, Demonstrating ROI Without Stifling Innovation, How to Make Governance an Enabler, Not a Brake, and more..."
In the second installment of this two-part series, Dr. Stacey Clardy talks with Drs. Ayush Gupta and Kuntal Sen about the spinal cord and optic neuritis, while outlining practical approaches to genetic testing and emphasizing the importance of collaboration with genetic counselors and neurogeneticists. Read the related article in Neurology® Genetics. Disclosures can be found at Neurology.org.
In part one of this two-part series, Dr. Stacey Clardy and Drs. Ayush Gupta and Kuntal Sen discuss the key clinical features that should shift suspicion from autoimmune encephalitis or demyelinating disease to monogenic mimics. Show citation: Gupta A, Sahjwani D, Kahn I, Gombolay GY, Sen K. Monogenic Mimics of Neuroinflammatory Phenotypes in Children and Young Adults: An Evolving Landscape. Neurol Genet. 2025;11(6):e200326. Published 2025 Nov 25. doi:10.1212/NXG.0000000000200326 Show transcript: Dr. Stacey Clardy: Hi, this is Stacey Clardy from the Salt Lake City VA in the University of Utah. For a two-part podcast series, I've been speaking with Ayush Gupta from the University of Nebraska Medical Center and Kuntal Sen from Children's National Hospital in Washington DC about the monogenic disorders that mimic neuroinflammatory disease that are lurking in all of our clinics just waiting to be diagnosed. Ayush, for the minute, when you're seeing a patient with a presumed autoimmune encephalitis or demyelinating disease, what single cluster of features should instead most strongly push us to think of monogenic mimics at the top of our differential? Dr. Ayush Gupta: So when you are seeing a patient with presumed autoimmune encephalitis or a demyelinating disorder, cluster of features such as earlier onset in terms of age, developmental delays, CSF or imaging finding that's non-concordant with the diagnosis such as a non-inflammatory CSF, a symmetric white matter or deep gray matter involvement and relentless progression despite immunotherapy, these are the red flags where you should stop, seriously consider the possibility of a monogenic disorder and reach out to help from colleagues. Dr. Stacey Clardy: That's a great list, and we get into far more detail in the two-part podcast series. So please listen to both of those and take a read of the neurology genetics review titled Monogenic Mimics of Neuroinflammatory Phenotypes in Children and Young Adults: An Evolving Landscape.
In part one of this two-part series, Dr. Stacey Clardy talks with Drs. Ayush Gupta and Kuntal Sen about the phenotypes commonly seen in CNS inflammatory and demyelinating diseases, and discuss genetic conditions in patients who do not precisely meet classic diagnostic criteria. Read the related article in Neurology® Genetics. Disclosures can be found at Neurology.org.
Join Dr. Mari Swingle, author of i-Minds, Joshua Moore, Anthony Moore, John Mekrut, and host Pete Jansons for an intimate, small-group discussion on neurofeedback scope challenges, the brain science behind obesity, and revolutionary QEEG phenotyping.✅ Scope of Practice Explained: Neurofeedback providers and neurologists often clash over EEG interpretation—neurologists prioritize seizures while neurotherapists catch subtle patterns linked to mental health; the group calls for mutual respect, better cross-training, and stopping discipline-bashing.✅ Obesity Epidemic Deep Dive: Obesity is multifactorial with strong brain ties—frontal slowing on EEG (mirroring ADHD/addiction phenotypes), trauma (ACEs), sedentary behavior, and mindless eating; fidgeting burns 800–2000 extra calories daily, while drugs like Ozempic help weight but skip behavioral roots.✅ QEEG Phenotypes Insights: Joshua Moore breaks down personalizing neurofeedback and medication via individual EEG phenotypes—up to 85% mental health improvement when meds match brain patterns vs. symptom-only prescribing.✅ Additional Topics:
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode1084. In this episode, I'll discuss what phenotype of patients are most affected by delays in antibiotic therapy.
Dr. Michael Snyder joins Dr. Forbes to discuss research showing that Type 2 diabetes represents multiple metabolic subtypes rather than a single condition. He explains how glucose curve patterns, oral glucose tolerance testing, and continuous monitoring can help identify differences in muscle insulin resistance, beta-cell function, hepatic signaling, and incretin response. The conversation explores how these physiological patterns may guide individualized nutrition strategies, medication selection, and earlier detection in people with emerging dysregulation.
Join us for the way overdue Microbruin about Spirit Bears! This special type of Kermode Bear is truly unique, so grab a bevvy and settle in for the ride.Find us on all the things: http://linktr.ee/bearsandbrewspodcast Sources Cited:Bourton, Jody. “BBC - Earth News - Spirit Bears Become “Invisible.”” Bbc.co.uk, BBC, 2025, news.bbc.co.uk/earth/hi/earth_news/newsid_8344000/8344367.stm. KLINKA, DAN R., and THOMAS E. REIMCHEN. “Adaptive Coat Colour Polymorphism in the Kermode Bear of Coastal British Columbia.” Biological Journal of the Linnean Society, vol. 98, no. 3, 27 Oct. 2009, pp. 479–488, https://doi.org/10.1111/j.1095-8312.2009.01306.x. “Research: Dietary Differences among Individuals with Different Genes and Coat Colours Gives Insight into the Maintenance of the Spirit Bears among Black Bear Populations | Raincoast.” Raincoast, 6 May 2021, www.raincoast.org/2021/05/research-dietary-differences-genes-spirit-bears-among-black-bear-populations/. “Saving the Kermode “Spirit” Bear.” National Wildlife Federation, 28 Jan. 2010, www.nwf.org/Magazines/National-Wildlife/2010/Kermode-bear.Service, Christina N., et al. “Intrapopulation Foraging Niche Variation between Phenotypes and Genotypes of Spirit Bear Populations.” Ecology and Evolution, vol. 11, no. 10, 13 Apr. 2021, pp. 5025–5037, https://doi.org/10.1002/ece3.7276. Hosted on Acast. See acast.com/privacy for more information.
Welcome to "Mind the Kids," where stories, science, and lived experience collide to shed light on the mysteries of child development. What if the answer to why some children struggle with attention or language isn't just written in their DNA, but also shaped by the world their parents create? In this episode, “Neurotypes, Genotypes and Phenotypes,” our hosts Professor Umar Toseeb and Dr. Jane Gilmour invite Dr. Laura Hegemann to talk about her JCPP paper ‘Direct and indirect genetic effects on early neurodevelopmental traits' and the wider implications of the topic. Laura unravels why understanding genetic influences isn't about fate or fatalism; it's a nuanced story of possibility, risk, and hope. Her research offers powerful new insights: the mix of direct genetic effects and subtle environmental influences, and why “knowledge is power” for clinicians and parents trying to support neurodiverse children. You'll hear candid reflections on why communicating these findings is fraught with risks and responsibilities—and stories of families who find both challenge and strength in their inherited traits. As you listen, expect real talk: about how early intervention makes a difference, why neurodevelopmental traits can be both a challenge and a gift, and how science can help us support—not stigmatise—those on different developmental paths. This isn't just another academic debate; it's a conversation about how research shapes practice and lives. So settle in for a journey through dilemmas, discoveries, and transformative moments in child behavioural genetics. The story starts here. More information: From the JCPP paper ‘Direct and indirect genetic effects on early neurodevelopmental traits' Laura Hegemann, Espen Eilertsen, Johanne Hagen Pettersen, Elizabeth C. Corfield, Rosa Cheesman, Leonard Frach, Ludvig Daae Bjørndal, Helga Ask, Beate St Pourcain, Alexandra Havdahl, Laurie J. Hannigan https://doi.org/10.1111/jcpp.14122
In this episode, Jesse Gordon-Blake, PhD, delves into the intricacies of medicinal chemistry, particularly focusing on drug discovery for ALS (amyotrophic lateral sclerosis). Jesse explains the process of discovering molecules that modulate biological pathways, the difference between structure-based and phenotype-based drug design, and the role computational methods play in drug development. The conversation also explores the challenges of crossing the blood-brain barrier, the importance of validating target response, and the complexities of progressing from a theoretical compound to preclinical studies. Additionally, Jesse touches on the significance of target product profiles, CNS drug design characteristics, and the iterative nature of medicinal chemistry. He concludes by discussing his current projects at Cortex, including fundraising strategies and timelines for drug development.00:00 Introduction to Medicinal Chemistry00:37 Drug Discovery Approaches02:01 Computational Methods in Medicinal Chemistry03:21 Challenges in ALS Drug Discovery04:23 Blood-Brain Barrier and Drug Design05:29 Key Properties for CNS Drug Design08:58 Day-to-Day in Drug Discovery09:45 Early Stage Drug Development12:28 Validating Drug Targets16:15 From Theory to Animal Testing22:46 Funding and Timeline Considerations25:45 Regulatory and Manufacturing Considerations28:32 Conclusion and Contact InformationDr. Jesse Gordon-Blake is an independent biotechnology and drug discovery consultant with expertise in medicinal chemistry and neurotherapeutics. He has led efforts in small molecule and peptide therapeutic development, AI-enabled drug discovery, and biotech startup formation, and currently serves as the CSO of Cortexa Therapeutics. He earned his PhD in Medicinal Chemistry from the University of Illinois at Chicago, focusing on developing innovative small-molecule enzyme modulators for Alzheimer's disease.https://www.linkedin.com/in/jesse-gordon-blake-phd-52a26274/https://www.cortexatherapeutics.com/Subhi Saadeh is a Quality Professional and host of Let's Combinate. With a background in Quality, Manufacturing Operations and R&D he's worked in Large Medical Device/Pharma organizations to support the development and launch of Hardware Devices, Disposable Devices, and Combination Products for Vaccines, Generics, and Biologics. Subhi serves currently as the International Committee Chair for the Combination Products Coalition(CPC) and as a member of ASTM Committee E55 and also served as a committee member on AAMI's Combination Products Committee.For questions, inquiries or suggestions please reach out at letscombinate.com or on the show's LinkedIn Page.
Join Jay Gunkelman, QEEGD (the man who has analyzed over 500,000 brain scans), and host Pete Jansons for another engaging NeuroNoodle Neurofeedback Podcast episode discussing neuroscience, psychology, mental health, and brain training.✅ Topic 1 Explained: What is the “Squash” protocol (aka Nurea)? Jay revisits its late-90s origins, the idea of generalized frontal suppression, and why “gamma is good” isn't always true in clinical contexts.✅ Topic 2 Deep Dive: Caffeine's impact on EEG—why withdrawal can slow alpha into theta, and how dopamine deficits (e.g., fronto-central theta in ADD) fit into stimulant vs. reuptake-inhibitor choices.✅ Topic 3 Insights: Why diagnosis-based studies (OCD/PTSD) show mixed results and how organizing by EEG phenotype predicts very different responses—especially with alpha patterns vs. beta spindling.✅ Additional Topics:
Novel Imaging Techniques and Phenotypes in Asthma and COPD
In this Twilight Zone-inspired episode of BioTA, two biology students prepping for lab encounter a pair of unexpected space travelers who want help unraveling a mystery: Why do some bacteria defy antibiotics while others perish? Why do some plants tolerate herbicides while others shrivel? With a crash course in the concepts of genotypes and phenotypes, the students explain some of the basic principles that life on Earth follows (most of the time).
Join us for another NeuroNoodle Neurofeedback Podcast episode featuring Jay Gunkelman, QEEGD (the man who has read over 500,000 brain scans) and Dr. Mari Swingle (author of i-Minds). Hosted by Pete Jansons, this episode dives into the controversy around unlicensed life coaches, the role of neurofeedback in mental health, and why executive coaching could benefit from EEG scans. ✅ Topics Discussed: ✅ Should life coaches be licensed to discuss mental health? ✅ The dangers of unregulated mental health coaching ✅ How neurofeedback can optimize brain function ✅ What EEGs reveal about procrastination and motivation ✅ The role of TMS (Transcranial Magnetic Stimulation) in mental health treatment ✅ How executive coaching could benefit from brain scans ⏱️ Key Moments: ✅ 0:00 Show Start ✅ 0:24 Bill aims to prevent unlicensed life coaches from practicing mental health therapy
DOI: 10.13056/acamh.13668 In this Papers Podcast, Dr. Franjo Ivankovic discusses their co-authored JCPP paper ‘Optimization of self- or parent-reported psychiatric phenotypes in longitudinal studies'. There is an overview of the paper, methodology, key findings, and implications for practice. Learning Objectives 1. The reliability and validity of consistent self-endorsement of a given psychiatric diagnosis. 2. Insight into the low agreement between parent-reported, child-reported, and clinician reported psychiatric phenotypes and why these different informants might report different levels of mental health difficulties when the target child is the same. 3. The over-endorsement and under-endorsement of symptoms of mental health difficulties when self-reporting and the impact on the prevalence of mental health conditions. 4. Insight into the Adolescent Brain Cognitive Development (ABCD) study and the narrow diagnosis construct. 5. Whether there is evidence of a relationship between the over-endorsement of symptoms of mental health conditions and a high level of public awareness of the symptoms of those conditions. 6. The implications of this study for other researchers and to what extent over-endorsement is a problem across the board in cohort studies and population level investigations, as well as recommendations moving forward.
Send us a textPatent Ductus Arteriosus and Lung Magnetic Resonance Imaging Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension.Bjorkman KR, Miles KG, Bellew LE, Schneider KA, Magness SM, Higano NS, Ollberding NJ, Hoyos Cordon X, Hirsch RM, Hysinger E, Woods JC, Critser PJ.Am J Respir Crit Care Med. 2024 Aug 1;210(3):318-328. doi: 10.1164/rccm.202310-1733OC.PMID: 38568735As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
For today's episode, we go back to the origins of Autism. It seems necessary because of the recent shifts in what is Autism and the confusion in the rates of Autism. Autism was here in the 1930's, and it magically showed up in different areas of the world. (Part 2 on Asperger's "little professors" next). The two-part series intends to remember the phenotypes that appeared and became known as Autism.It is my opinion, the recent shifts in defining Autism could be rooted in questionable intentions. Regardless, one goal of the podcast is understanding and explaining Autism. By the end of the episode, and by the end of the two-part series, I hope you gain understanding of the Autistic Phenotype.Leo Kanner: Autistic Disturbances of Affective Contact http://www.autismtruths.org/pdf/Autistic%20Disturbances%20of%20Affective%20Contact%20-%20Leo%20Kanner.pdf0:00 Intro0:45 Erwin Schrödinger Quote; Quantum Physics; Missing link in Medicine2:56 Kanner's Autistic Disturbances of Affective Contact; Demographics3:52 Ages; Boys versus Girls; Phenotypes; Family History6:26 Important consideration of Family History- electricity and nnEMF; general observation and important phenotypes9:30 Anticipatory Motor Adjustment; Reflexes; Sensory and Adaptive Responses13:32 Monotonous Repetitions; Sameness15:26 Spelling and Language18:20 Commands and Intrusions18:57 Autism, not Autism and ADHD; Intense Fixations & Neuroplasticity; Default Mode Network; Sameness24:00 Oblivious to Others; Inattentive- It's not ADHD, it's Autism27:39 Changes & More on Sameness & Repetitions30:10 Rote Memory; Gastrointestinal: Timelines and MilestonesX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
The ability of human pluripotent and somatic stem cells to differentiate into multiple cell types of the human body makes them uniquely useful to model human development and disease. As a result, these cells are shared, edited, and differentiated by laboratories across the world for basic research, clinical translation, and commercial applications. Large and genotypically diverse collections of pluripotent stem cells are being generated to support large cohort-scale research into conditions such as Parkinson's disease and amyotrophic lateral sclerosis, among many others. However, information about these cells, their derivatives, and the resulting data can be difficult to track due to a myriad of factors including poor naming practices, siloed datasets, and incomplete information on experimental practices in the published literature. As a result, the ability to maximize the utility of these cells and data from them is limited, and the rigor and reproducibility of the research and its application may be seriously compromised. Our guests today, who were part of the ISSCR Task Force that developed the Standards for the Use of Human Stem Cells in Research, will discuss in detail a framework to manage these issues using stem cell registries. GuestAndreas Kurtz, PhD, Fraunhofer Institute for Biomedical Engineering and the Berlin Institute of Health Center for Regenerative Therapies Christine Wells, PhD, University of Melbourne Centre for Stem Cell Systems HostMartin Pera, Editor-in-Chief, Stem Cell Reports and The Jackson LaboratoryX: @martinperaJAXSupporting ResourcesGuidelines for managing and using the digital phenotypes of pluripotent stem cell lines, Stem Cell ReportsAbout Stem Cell ReportsStem Cell Reports is the open access, peer-reviewed journal of the International Society for Stem Cell Research (ISSCR) for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.X: @StemCellReportsAbout ISSCRWith nearly 5,000 members from more than 80 countries, the International Society for Stem Cell Research (@ISSCR) is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.ISSCR StaffKeith Alm, Chief Executive OfficerYvonne Fisher, Managing Editor, Stem Cell ReportsKym Kilbourne, Director of Media and Strategic CommunicationsJack Mosher, Scientific AdvisorVoice WorkBen Snitkoff
Send us a textBen and Daphna speak with Dr. Aaron Hamvas from Lurie Children's Hospital about his research on bronchopulmonary dysplasia (BPD) and its potential genetic factors. Dr. Hamvas discusses the complexities of BPD, including the role genetics might play in predisposing infants to the condition. He introduces the “Leopard Project,” a new NIH-funded study using AI and novel genomics techniques to explore long-term respiratory outcomes in preterm infants. Join the conversation for insights into how genetics and advanced data analysis could redefine our understanding of BPD and its lifelong impacts.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
Welcome to another live Q&A session from NeuroNoodle! In this episode, Pete Jansons hosts an expert panel, including Jay Gunkelman, Dr. Mari Swingle, Joy Lunt, Dr. Andrew Hill, Santiago Brand, Anthony Ramos, and John Mekrut. They dive deep into neurofeedback's impact on autism, ADHD, mental health, and brain training. Hear insightful discussions, real-time audience questions, and practical applications for neurofeedback therapy.
The Conversation is BACK, and in this episode, we welcome @Joint_the_huntsman back to the program. He's here to give us a full rundown of his latest breeding work - a DOUBLE drop coming this Friday. Did I mention that there's an official Cultivation Conversation grow along to go with this drop? WELL THERE IS! Get in on the game and grab a pack of beans or six at jcuniversal.link this Friday, 10/18.
In this episode, we discuss Autism and the Default Mode Network. According to Lisa Feldman-Barrett, the Default Mode Network has many names because it has been discovered, named, rediscovered, and renamed many times. I do not disagree with the Science regarding Autism and the Default Mode Network. However, I disagree with the Interpretation of the Data. This IS our Default; our preferred state; the core of the Autistic Phenotype.After listening to this episode and understanding B.3, you can understand MOST of Autism. The only reason you cannot understand ALL of Autism from these two episodes is the amount of Phenotypes branching off of B.3 and our Default Mode. Autism IS preference for ALONENESS and SAMENESS. This minimizes sensations and distractions that interfere with our internal world. This state is NOT abnormal, how society interferes with it makes it abnormal.If you want more Autistics to ACHIEVE, then understand your interaction, interference, and interpretation of what YOU think Autism is provides the delta of how much we are prevented in life. This, of course, becomes slightly different the more profound the Autistic Phenotype is with that specific person.In this episode, we will explore the different brain regions and the goals of these regions as it relates to our phenotypes. We will get into some "Thinking in Picture" and thinking styles. This will be a good time because of a future guest on From the Spectrum Podcast discussing Autism and Creativity. This is exciting for me.Lisa Feldman-Barrett Core System (DMN) https://lisafeldmanbarrett.com/2017/02/05/core-systems/0:41 Research at UT-Austin and the Importance of the INFRARED LIGHT study with Autism5:48 Autism and the Default Mode Network (DMN); Buzzword in Science7:19 Humans and our Prediction Machine and Sensory Processing; Innate or Learned; Oxytocin in the Autistic Phenotype;9:36 History of DMN (from Lisa Feldman-Barrett) and the many names; Core Systems11:58 medial Prefrontal Cortex (covered in many episodes); roles, E/I, connectivity, Internal Calculators14:45 Posterior Cingulate Cortex (PCC); Self-Referential Thinking, Memory, Attention, Task-Switching and the harms of calling it ADHD18:03 Angular Gyrus; Language, Sensory Processing "Bee Movie" example, Mental Images, Narratives, Empathy21:12 Supplementing Relationships23:36 Sensation-Perception24:30 Precuneus; Self-Awareness, Episodic Memory, Prediction and Strategic Planning25:52 Social Cognition; Social Cues and Skills27:50 Autism and Anxiety- Avoidance, Breathing (Physiology), and Valence (how we feel)28:48 Internal Calculators; Metabolic Bank Account and Demands29:26 the DMN is a Misnomer and the Default (tendency, phenotype) of the Autistic33:04 Reviews/Ratings, Contact InfoX: https://twitter.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
Welcome to Season 2 of the Orthobullets Podcast. Today's show is Podiums, where we feature expert speakers from live medical events. This episode will feature Dr. Jean Jacques Abitbol, and is titled Understanding the Phenotypes of Low Back Pain. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
Charles Mayfield is the founder of Farrow Skincare, an animal-based skincare product that does not contain fillers, additives, and other harmful chemicals. Charles became fascinated by the benefits of lard on the skin when he made the connection between the biology of humans and pigs. The origins of Farrow all started after a long day out in the July Tennessee sun. Charles decided to use some lard from his farm to protect his skin from peeling out of necessity and it wasn't until the next day that he realized his skin never peeled and his burn had vanished. At that point, Charles realized he was on to something. Now, Charles is on a mission to bring lard-based skincare to the masses and convince people to throw away their toxic skin creams.Key topics discussed:- The benefits of cooking and consuming nutrient-dense, whole foods- The negative effects of modern lifestyle choices on physical health and how they can be reversed- The significance of using natural skincare products over conventional ones- The importance of understanding and improving metabolic health- The role of mental belief and positive mindset in the healing processTimestamps:(01:00) - The Bastardization of Pork in Media(02:00) - Historical Use of Lard and Tallow(05:00) - Modern Pig Breeding and Phenotypes(10:00) - Transition to Seed Oils and Fast Food Industry(12:00) - Skincare with Animal Fats(15:00) - Discussion on Sunscreens and Natural Alternatives(20:00) - Societal Health Decline and Reversal Opportunities*** SPONSOR ***CrowdHealth - They're providing an alternative to health care coverage in the form of a community-based approach.We've both used this service for the last two years. Check out their new Carnivore Crowd and if you sign up be sure to use code MEATMAFIA for a discount on your first 3 months!*** LINKS***Check out our Newsletter - Food for Thought - to dramatically improve your health this year!Join The Meat Mafia community Telegram group for daily conversations to keep up with what's happening between episodes of the show.Connect with Farrow Skincare:WebsiteTwitterInstagramConnect with Meat Mafia:Instagram - Meat MafiaTwitter - Meat MafiaYouTube - Meat MafiaConnect with Noble Protein:Website - Noble ProteinTwitter - Noble ProteinInstagram - Noble ProteinAFFILIATESLMNT - Electrolyte salts to supplement minerals on low-carb dietThe Carnivore Bar - Use Code 'MEATMAFIA' for 10% OFF - Delicious & convenient Pemmican BarPerennial Pastures - Use CODE 'MEATMAFIA' 10% OFF - Regeneratively raised, grass-fed & grass-finished beef from California & MontanaFarrow Skincare - Use CODE 'MEATMAFIA' at checkout for 20% OFFHeart & Soil - CODE ‘MEATMAFIA' for 10% OFF - enhanced nutrition to replace daily vitamins!Carnivore Snax - Use CODE 'MEATMAFIA' Crispy, airy meat chips that melt in your mouth. Regeneratively raised in the USA.Pluck Seasoning - 15% OFF - Nutrient-dense seasoning with INSANE flavor! Use CODE: MEATMAFIAWe Feed Raw 25% OFF your first order - ancestrally consistent food for your dog! Use CODE 'MEATMAFIA'Fond Bone Broth - 15% OFF - REAL bone broth with HIGH-QUALITY ingredients! It's a daily product for us! Use CODE: MAFIA This episode of the podcast is brought to you by the CarnivoreCrowd over at CrowdHealth. When we first quit our jobs to focus on the podcast and Noble Origins full-time, we immediately signed up for CrowdHealth. They just launched their CarnivoreCrowd, which is designed to bring together metabolically healthy individuals into a cost-sharing community for medical bills. I don't know about you guys, but it's great knowing that the other members of the community care about their health as much as I do. If you're interested in joining the CarnivoreCrowd, use the code MEATMAFIA for $99 for the first three months. Also, check out the founder of CrowdHealth on episode 240 of The Meat Mafia Podcast.
Send us a Text Message.In this episode of Causes or Cures, Dr. Eeks chats with Dr. Andres Acosta MD PHD about the identification of 4 phenotypes for obesity and how they can revolutionize the future of obesity treatment. In great detail, he describes the 4 obesity phenotypes (Hungry Brain, Emotional Hunger, Hungry Gut, and Slow Burn) and explains what treatment, diet, and exercise plan works for each. He also describes his company, Phenomix Sciences, a precision-medicine company that predicts how well someone will respond to various obesity interventions. Dr. Acosta is a Consultant of Gastroenterology and Hepatology at the Mayo Clinic, as well as an Associate Professor of Medicine. His research focus is on gastrointestinal physiology and the complexity of food intake regulation as it relates to obesity. You can learn more about his work here. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her monthly newsletter here.Support the Show.
Dr. Nadia Khalil interviews Dr. Collin Grant on his experience in private practice. He shares his take on the highlights, challenges, and keys for success.
The Conversation is BACK, and in this episode, we discuss Schedule III, home gardening, summertime growing, a couple new products, and 3 leaf phenos. So sit back, relax, grab something to smoke on and get ready for a Cultivation Conversation. Please follow the show at @cultivation.conversation and follow your hosts at @girlgogrow, @therealgreenmonsta & @captainautoflower. Don't forget to like, comment, share & subscribe because all of that helps us A LOT! Thanks everyone and enjoy the show. DISCOUNT CODES AUTOPOTS - Use code "CC10" on autopot-usa.com MICROBELIFEHYDRO - Use code "CCMLH15" on https://microbelifehydro.com AC INFINITY - Use code "cultivation" on acinfinity.com INSECT FRASS - Use code "CC10" frassvalley.com EVERYTHING - Use code "CC10" on mass-hydro.com If you would like to support us on patreon Join us on discord Follow us on twitch Our website Products we use
Dr. Nadia Khalil interviews Dr. Ileana Howard and Dr. Kelly Gwathmey on their careers in neuromuscular medicine. They define a neuromuscular practice and highlight how meaningful, challenging, and exciting this field of medicine is.
Dr. Mrinalini Dey discusses abstract OP0202 presented at Eular 2024 in Vienna, Austria.
Dr. Nadia Khalil interviews Dr. Nicholas Johnson on a career in research. He describes what research in practice looks like, his inspiration, and pearls for success.
Dr. Nadia Khalil interviews Dr. Milind Kothari and Dr. Sandra Hearn on academic practice. They define what life as a clinician educator looks like and share pearls from their own journeys for success.
Dr. Celina Nahyun Jo, one of the trainee editorial board members in Radiology: Imaging Cancer and a radiology resident at University of Texas Medical Branch in Galveston hosts our podcast series that summarizes interesting articles into a bite size. This podcast provides background knowledge for everyone to understand and enjoy oncologic imaging research on the go. This is bite size research for Radiology: Imaging Cancer, November 2023 issue." Current Status of Cancer Genomics and Imaging Phenotypes: What Radiologists Need to Know. Serrão et al. Radiology: Imaging Cancer 2023; 5(6):e220153.
What are the ways that patients fail breathing trials, and what can they tell us about how to optimize them for next time?
#addiction #neurofeedback #neurofeedbacktherapy #phenotypes #mentalhealth #shorts #mentalhealthshorts Main Clip: https://youtu.be/QeJ7j9BfE3M Jay Gunkelman is the man who has read over 500,000 brain scans and in this short he talks about the phenotypes present on brains with addiction --- Send in a voice message: https://podcasters.spotify.com/pod/show/neuronoodle/message Support this podcast: https://podcasters.spotify.com/pod/show/neuronoodle/support
ARDS Part II Special Guest: Steven Lemieux, PharmD, BCPS, BCCCP 03:45 – ESICM guidelines and ARDS definition 11:50 – Phenotypes and respiratory support 23:50 – Corticosteroids 34:40 – NMBA, pulmonary vasodilators, and VV ECMO 44:00 - Fun facts and take-home points Reference List: https://pharmacytodose.files.wordpress.com/2023/08/ards-part-ii-references.pdf PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices
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