Podcasts about Clinical research

Natalie Crawford, MD is double board certified in both Obstetrics and Gynecology and Reproductive Endocrinology and Infertility and author of the bestselling book, The Fertility Formula. She is co-founder of Fora Fertility, a boutique fertility practice in Austin, Texas and CEO and co-founder of Learn at Pinnacle, a medical education network. Dr. Crawford completed her undergraduate at Auburn University obtaining a degree in Nutrition Science, Medical School at University of Texas Medical Branch, OBGYN Residency at University of Texas Southwestern, and REI Fellowship at University of North Carolina, concurrently obtaining a Master of Science in Clinical Research. Today on the show we discuss how cannabis and alcohol affect fertility in men and women, how long reproductive health may take to recover after quitting, the surprising relationship between GLP 1 medications and fertility, how chronic stress and insulin resistance can make it harder to conceive, the five lifestyle habits that support healthier eggs and sperm, and why proactive fertility testing can help couples avoid losing valuable time. Try Momentous Signature Spec Creatine: https://www.livemomentous.com Use code ADVERSITY for up to 35% off your entire first order Learn more about your ad choices. Visit megaphone.fm/adchoices

Cancer treatments have changed dramatically over the past decade, but have our dose-finding strategies kept pace? In this episode, I speak with Dr. Ayon Mukherjee, who leads statistical innovation in early oncology development at Eli Lilly. Together, we explore Project Optimus, the FDA initiative that is changing how we think about dose optimization in oncology. Instead of simply finding the highest dose patients can tolerate, Project Optimus encourages us to identify the dose that provides the best balance between efficacy, safety, pharmacokinetics, pharmacodynamics, and long-term tolerability. Ayon explains why the traditional maximum tolerated dose approach worked well for chemotherapy but often falls short for targeted therapies and immunotherapies. We also discuss how statisticians can help lead this transformation by designing better dose optimization studies and collaborating more effectively with clinicians, pharmacologists, and regulators.

My Free tools for sites and researchers: https://coordinare.co/Free EDC Tool: https://crc-edc-sandbox.netlify.app/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

Hi guys! Today's episode is super duper long and I truly have stopped caring, there's so much corruption in this world and it deserves to be covered. What corruption are we going over this week? Glad you asked! This is a continuation on our deep-dive into WHY women were actually banned from clinical research in 1977. It is absolutely crucial we understand who is behind this as *ahem* women matter and it's also Disability Pride Month! Thank you all for taking the time to listen or at least check out the resources (scroll down for the databases) - if any sources are missing it's because Youtube and podcast sites usually have a 5K letter limit. I'm using those letters explaining this - but if you need to find something, write down the key words I used and type them into ToxicDocs. By the way, NO, this is not sponsored by ToxicDocs as that's not how research databases roll. I'm just a fan. I appreciate you all! Thank you again for listening. Books: Sweet and Deadly: How Coca-Cola Spreads Disinformation and Makes Us Sick - Murray Carpenter Seed Money: Monsants's Past and Our Food Future - Barrow J. Elmore Unsavory Truth: How Food Companies Skew the Science of What We Eat - Marion Nestle  Books for Disability Pride: Against Technoableism: Rethinking Who Needs Improvement - Ashley Shew Disability Pride: Dispatches From a Post-ADA World - Ben Mattlin All Tangled Up in Autism and Chronic Illness: A Guide to Navigating Multiple Conditions - Charli Clement Sources: Summary of the Toxic Substances Control Act - 1976 https://www.epa.gov/laws-regulations/summary-toxic-substances-control-act  Superfund Amendment And Reauthorization Act of 1986 https://www.safeopedia.com/definition/9779/the-superfund-amendment-and-reauthorization-act-of-1986-sara AIM Packaging, Inc. - Sept. 6, 1977 https://cdn.toxicdocs.org/ga/gaGeEo51Z9VojeXodBNRpJEGQ/gaGeEo51Z9VojeXodBNRpJEGQ.pdf August 10, 1976 - Female Employment in Restricted Areas https://cdn.toxicdocs.org/yr/yrVo4zNGqz6Gn35jMvyne1Qa2/yrVo4zNGqz6Gn35jMvyne1Qa2.pdf Donald Kennedy and Department of Naval Research & Monsanto https://en.wikibooks.org/wiki/Professionalism/Stanford_Research_Scandal Declassified document between Navy and Monsanto: https://apps.dtic.mil/sti/pdfs/AD0837462.pdf Carter's Great Purge (July 29, 1979) https://time.com/archive/6881566/carters-great-purge/ Carter, in Angry Exchange, Ousts Bella Abzug From Women's Unit https://www.nytimes.com/1979/01/13/archives/carter-in-angry-exchange-ousts-bella-abzug-from-womens-unit.html?eafs_enabled=false  The Big Businessmen Who Have Jimmy Carter's Ear https://www.nytimes.com/1978/02/05/archives/the-big-businessmen-who-have-jimmy-carters-ear-carter.html Monsanto - Report by PCB Study Group Dec. 10, 1975 (Discussion of Brand Pivot) https://cdn.toxicdocs.org/Rj/Rjz55o2VvobRJyRKL5JzZ077V/Rjz55o2VvobRJyRKL5JzZ077V.pdf Timeline of Monsanto - https://en.wikipedia.org/wiki/Timeline_of_Monsanto Reproductive Hazards in the workplace https://cdn.toxicdocs.org/GK/GKoeDy2kzLezwkNO7XQ61BmNV/GKoeDy2kzLezwkNO7XQ61BmNV.pdf Erectile Dysfunction: A Review of Historical Treatments  https://pmc.ncbi.nlm.nih.gov/articles/PMC5675239/ Somatization Disorder Symptoms https://neupsykey.com/somatization-disorder-and-related-disorders/  Somatization Disorder (300.81) – DSM 4 https://courses.lumenlearning.com/atd-herkimer-abnormalpsych/chapter/somatization-disorder-300-81/  Environmental Erectile Dysfunction: Can the Environment Really Be Hazardous to Your Erectile Health? https://onlinelibrary.wiley.com/doi/full/10.2164/jandrol.107.004200#b23  Timeline: History of Endocrine Disrupting Chemicals https://heeds.org/heeds-timeline/ Databases Mentioned: Comparative Toxicogenomics Database https://ctdbase.org/ DEDuCT: Database of Endocrine Disrupting Chemicals and their Toxicity Profiles https://cb.imsc.res.in/deduct/home UCSF - University of California San Francisco - Industry Documents Library https://www.industrydocuments.ucsf.edu/home/ Physicians for Social Responsibility  https://psr.org/ Science Action Network for Health and the Environment https://prhe.ucsf.edu/science-action-network Open Textbook Library  https://open.umn.edu/opentextbooks/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

My Free tools for sites and researchers: https://coordinare.co/Free EDC Tool: https://crc-edc-sandbox.netlify.app/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

You've got a bottle of extra virgin olive oil sitting in your kitchen right now. I'd bet money on it.But I'd also bet you're only using it for one thing, cooking. Maybe the occasional salad dressing if you're feeling fancy. What if I told you that's like buying a Swiss Army knife and only ever using it to open envelopes?In this episode, I'm sharing eight science-backed ways olive oil can transform your health, and none of them involve a salad. We're talking about your brain, your joints, your gut, your skin, your ears, and even your snoring. Yes, really.This golden liquid has been used medicinally for thousands of years, and modern research is finally catching up to what the ancients already knew. By the end of this episode, you're going to look at that bottle on your counter completely differently.On this episode, you'll learn: How you can transform your oral health by doing THIS surprising hack (01:44)Why snoring can be your body signaling a much deeper issue (03:03)The skin secret Cleopatra and Sophia Loren both swore by (04:20)The incredible study that resulted in MRI-confirmed brain changes, improved memory, attention span, and executive function (05:34)The one mistake most people are making when it comes to their ear health (07:51)Which household item outperformed a prescription pain gel (08:45)The virtually free morning ritual that can kickstart digestion and support a healthy bowel rhythm (09:59)Why what you see on your scalp is really a sign of systemic inflammation (11:06)Three things to look for on an olive oil label before you buy (12:21)For full show notes and transcript: https://drgundry.com/olive-oil-health-benefits-science-backedThank you to our sponsors! Check them out: Get $20 off your first box plus a free year of protein, like sirloin or ribeye at ButcherBox.com/GUNDRY.Go to timelinenutrition.com/GUNDRY to get 10% off any Timeline Nutrition product.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most clinical research treats patients like data points. What gets lost when researchers stop listening to the people they study, and what does it cost the science itself? Niharika Singh is a biomedical engineer and pre-medical student with research experience at Genentech, Abbott, AstraZeneca, and the Keck School of Medicine, and a global ambassador with the United Nations SURGhub. She discusses the KevinMD article "Patient involvement transforms modern clinical research." You will hear the difference between treating a patient as a data set, engaging them as a collaborator, and inviting their emotional and lived experience into the study design. She walks through the Tiger Project hernia training across India and Ghana, what medical device design verification taught her about surgical research, and why AI in medicine is making patient voice harder to hear. You will hear a research methodology that treats the patient's voice as data worth collecting, and a case for defending human connection as AI changes how medicine is practiced. Partner with me on the KevinMD platform. With over three million monthly readers and half a million social media followers, I give you direct access to the doctors and patients who matter most. Whether you need a sponsored article, email campaign, video interview, or a spot right here on the podcast, I offer the trusted space your brand deserves to be heard. Let's work together to tell your story. PARTNER WITH KEVINMD → https://kevinmd.com/influencer SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended

Monica's LinkedIn: https://www.linkedin.com/in/monica-cuitiva/My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

In this episode of ACRO's GCP, Tinaya Gray (Executive Director, Site Engagement & PACE at ICON plc), Jan Hewett (SVP, FDA Regulatory Advisor at Advarra), and Jackie Kent (Independent Advisor) unpack the work of ACRO's dive team on representative, generalizable clinical trial data at the 2025 Innovation Network Gathering. Together, they explore why clinical trial populations still fail to reflect real-world patients, and what's been holding the industry back from meaningful progress.The conversation goes beyond identifying the problem. The group shares how a diverse set of stakeholders were able to align around practical, implementable solutions. They also discuss how industry can pilot new approaches, engage broader stakeholders, and turn promising ideas into standard practice. This episode offers a candid and solutions-oriented look at how to generate clinical data that truly supports better decision-making for all patients.

My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

In this episode of the Gladden Longevity Podcast, Dr. Gladden and Leslie Kenny delve into the intricacies of aging, health, and the role of spermidine in promoting longevity. They discuss the hallmarks of aging, Leslie's personal journey with autoimmune conditions, and the importance of empowerment and curiosity in health management. The conversation emphasizes the interconnectedness of health factors and the need for a holistic approach to wellness. In this conversation, Leslie Kenny and Dr. Gladden explore the potential of spermidine as a breakthrough in aging research, discussing its effects on health, longevity, and cellular processes like autophagy. They share personal experiences with spermidine, the challenges of clinical research, and the importance of redefining aging. The conversation also highlights resources for healthy aging and the significance of mindset in health management.   For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now   Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!    Takeaways ·       Spermidine positively impacts multiple hallmarks of aging. ·       Crosstalk between hallmarks of aging can enhance health. ·       Mindset plays a crucial role in health outcomes. ·       Patients should collaborate with their healthcare providers. ·       Curiosity in medicine leads to better patient outcomes. ·       The healthcare system often lacks time for curiosity. ·       Empowerment in health management is essential. ·       Modulating the immune system can restore balance. ·       Personal experiences can lead to significant health insights. ·       Holistic approaches to health can yield better results. Spermidine activates autophagy, aiding in cellular renewal. ·       Chronic management of illnesses is not desirable; patients want solutions. ·       Biological age can be significantly lower than chronological age. ·       Spermidine has potential benefits for heart health and cognition. ·       Personal experiences with spermidine show promising results in sleep quality. ·       Clinical trials for food-derived compounds face financial challenges. ·       The body can adapt and respond positively to the right inputs. ·       Redefining aging is crucial for a healthier future. ·       Mindset plays a vital role in health and aging. ·       Resources like Oxford Health Span can provide valuable information.       Chapters 00:00 Introduction to Longevity and Health 05:23 The Role of Spermidine in Aging 08:52 Personal Journey with Autoimmune Conditions 12:34 Empowerment in Health Management 18:07 The Importance of Curiosity in Medicine 25:21 Finding Balance in Immune Health 31:32 The Quest for Longevity and Health 34:58 Spermidine: A Breakthrough in Aging Research 39:14 Personal Experience with Spermidine 44:40 Challenges in Clinical Research 49:52 Redefining Aging and Health 52:52 Resources for Healthy Aging   To learn more about Leslie Kenny: Instagram: https://www.instagram.com/lesliesnewprime/ Website: oxfordhealthspan.com, lesliesnewprime.com   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw       Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

Dr. Matthew Ithurburn, Director of Clinical Research at the American Sports Medicine Institute (ASMI) in Birmingham, Alabama, joins us to talk about the research shaping the future of sports medicine. Dr. Ithurburn leads ASMI's clinical research team, working alongside Andrews Sports Medicine and Orthopaedic Center on outcomes studies, longitudinal research, and surgical and biologic clinical trials. We dig into what this research means for athletic trainers on the ground, how it's translating into better outcomes for athletes, and where the next breakthroughs in injury prevention and recovery might come from.For more information about PBATS and athletic training, visit pbats.com. 

David Stamler, M.D., Chief Executive Officer AlterityTherapeuticsAlterity Therapeutics (NASDAQ: ATHE & ASX: ATH)www.alteritytx.com  David Stamler, M.D., Chief Executive OfficerDavid Stamler, M.D. is Chief Executive Officer and a Managing Director, and previously served as Alterity's Chief Medical Officer and Senior Vice President, Clinical Development. Dr Stamler has extensive drug development expertise spanning early-stage research through late-stage clinical trials, with three FDA drug approvals in neurology.Prior to joining Alterity, Dr. Stamler served as the Vice President, Clinical Development and Therapeutic Head for Movement Disorders at Teva Pharmaceutical Industries after Teva acquired Auspex Pharmaceuticals where he was Chief Medical Officer.Prior to Auspex, he served as Senior Vice President and Chief Medical Officer at XenoPort, Inc., and Head of Drug Development at Prestwick Pharmaceuticals, Inc. Before Prestwick, Dr. Stamler worked at Fujisawa Pharmaceutical Co. and its subsidiaries in various leadership roles, including Vice President, Research and Development, Medical Sciences at Fujisawa Healthcare, Inc., and as Vice President, Clinical Research Center at Fujisawa Research Institute of America. Dr. Stamler began his career at Abbott Laboratories where he served in various positions including Director of Clinical Research, Pharmaceutical Products for the International Division.Dr. Stamler received an M.D. from the University of Chicago—The Pritzker School of Medicine and a B.A. in Biology from the University of Chicago.

In today's episode, Haylie Pomroy sits down with neurologist Dr. Daniel Kantor, President Emeritus of the Florida Society of Neurology and VP of Clinical Research and Development at the Gateway Institute for Brain Research, for a conversation that challenges how most people think about unexplained symptoms, chronic illness, and the doctor-patient relationship. Dr. Kantor walks through why over-reliance on MRI results has left a generation of patients told nothing is wrong with them, why the nervous system, immune system, and gut microbiome communicate in ways most clinical silos never account for, and why gluten in the American food supply is a fundamentally different substance from what people eat in Europe. He also goes deep on the most disabling aspect of chronic illness, and it is not weakness or physical limitation. It is uncertainty.  One in five Americans lives with a chronic illness, and most of them go years before getting a diagnosis that helps them make sense of their experience. This conversation is for them. Tune in to Fast Metabolism Matters. If your body feels like it's running on empty, overburdened, or just not responding the way it used to, Haylie's latest book, Toxic Overload, tells you exactly what to do. Download your free digital copy today and start understanding what your body is trying to tell you.   Free Download: Get Your Copy of Toxic Overload

Artificial intelligence is reshaping clinical research, but its impact extends far beyond automation. In this episode of ACRO's Good Clinical Podcast, host Sophia McLeod is joined by Paulo Limgenco (VP, Business Operations at YPrime) and Michael Tucker (VP, Patient Experience - Commercial at Medidata) to explore how AI and digital technologies are helping the industry build more sustainable, efficient, and patient-centered clinical trials.From protocol optimization and site selection to localization and decentralized trial models, the conversation examines how AI can reduce operational burdens, minimize waste, and expand access to research opportunities for underrepresented populations. The discussion also highlights the importance of responsible AI adoption, including strong governance frameworks, data stewardship, and human oversight.Tune in for an insightful conversation on how the industry is balancing innovation and responsibility while working toward a future where clinical trials are more efficient, inclusive, and sustainable for patients, sites, sponsors, and communities worldwide.

Jaime's LinkedIn: https://www.linkedin.com/in/jaime-valles-2a1728221/My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

In this episode, Dr Elle Wadsworth talks to Dr Amy Peacock, an Associate Professor and Deputy Director of the National Drug and Alcohol Research Centre, University of New South Wales, and Dr Krista Siefried, a Clinical Research Lead and Deputy Director, of the National Centre for Clinical Research on Emerging Drugs at the University of New South Wales, Australia. The interview covers two research articles: 1) Amy's article on trends in gamma-hydroxybutyrate (GHB) use, harms and treatment in Australia and 2) Krista's article on emergency department presentations, hospitalisations and police seizure data related to GHB in New South Wales, Australia.What is GHB? [01:30]Why is GHB an important drug to examine in the Australian population [02:30]The data sources Amy used in her study [04:20] The data sources Krista used in her study [06:45]The key findings of the study [08:21]Metabolites of GHB and risks of consuming GHB with alcohol [13:20]The implications of the findings for policy and treatment in Australia [14:04]The reasons behind the recent increase of GHB in Australia [16:30]The take home messages [19:14]About Elle Wadsworth: Elle is an academic fellow with the Society for the Study of Addiction. She is based at the University of Bath with the Addiction and Mental Health Group, and her research interests include drug policy, cannabis legalisation, and public health. Elle holds voluntary roles at The Loop, a non-profit service provider of drug checking in the UK and the International Society for the Study of Drug Policy. About Amy Peacock: Amy is an Associate Professor, National Health and Medical Research Council (NHMRC) Emerging Leadership Fellow and Deputy Director of the National Drug and Alcohol Research Centre, University of New South Wales. She is also Program Lead for Drug Trends, a national monitoring system identifying trends in illicit drug use, markets and harms that is funded by the Australian Government Department of Health, Disability and Ageing.About Krista Siefried: Krista is Clinical Research Lead and Deputy Director, the National Centre for Clinical Research on Emerging Drugs (NCCRED) at the University of New South Wales (UNSW) in Sydney, Australia. She is also a Senior Lecturer at the UNSW National Drug and Alcohol Research Centre (NDARC), and St Vincent's Hospital Sydney Alcohol and Drug Service. Krista works towards evidence-based interventions to reduce harm and improve healthcare for people who use drugs. Her leadership emphasises collaborative research, deep community engagement, and practical outcomes to address the needs of individuals, families, and frontline service providers.Declarations of interest: Krista is employed by the UNSW and St Vincent's Health Network Sydney, she has no other conflicts to declare. Original articles: Emergency department presentations, hospitalisations and police seizure data related to gamma-hydroxybutyrate (GHB) in New South Wales, Australia, from 2015 to 2024 https://doi.org/10.1111/add.70202 Trends in gamma-hydroxybutyrate use, harms and treatment in Australia, 2013 to 2024 https://doi.org/10.1111/add.70308The opinions expressed in this podcast reflect the views of the host and interviewees and do not necessarily represent the opinions or official positions of the SSA or Addiction journal.The SSA does not endorse or guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information. Hosted on Acast. See acast.com/privacy for more information.

Kaye's LinkedIn: https://www.linkedin.com/in/kaye-doiron-209b5487/My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

Elevated GP - Click here to join Elevated.GP Follow @dr.melissa_seibert on Instagram Dr. Peter Milgrom is Professor of Oral Health Sciences and Pediatric Dentistry in the School of Dentistry and adjunct Professor of Health Services in the School of Public Health at the University of Washington. He directs the Northwest Center to Reduce Oral Health Disparities. He holds academic appointments at Case Western University, University of Rochester, and University of California, San Francisco. He maintains a dental practice limited to the care of fearful patients and served as Director of the UW Dental Fears Research Clinic. Dr. Milgrom's work includes research on xylitol, the effectiveness of fluoride varnish and iodine in preschoolers, clinical efficacy and safety of diammine silver fluoride, motivational strategies to increase perinatal and well child dental visits in rural communities, and studies of cognitive interventions in pediatric and adult dental fear. The NIH, Maternal and Child Health Bureau, HRSA, and the Robert Wood Johnson Foundation support his work. Dr. Milgrom is author of 5 books and over 300 scientific articles. His latest book, Treating Fearful Dental Patients, was published in 2009.   Dr. Milgrom was Distinguished Dental Behavioral Scientist of the International Association for Dental Research for 1999. In 1999, and again in 2000, his work was recognized by the Giddon Award for research in the behavioral sciences in Dentistry. He received the Barrows Milk Award from IADR in 2000, recognizing his work for public health including the development of the Access to Baby and Child Dentistry (ABCD) program in Washington State. In 2003, Dr. Milgrom received a Special Commendation Award from the National Legal Aid and Defenders Association and the University of Washington Medical Center Martin Luther King, Jr. Community Service Award. In 2010, he received the Aubrey Sheiham Research Award for his work on xylitol. He serves on scientific review committees for the NIDCR, NIMHHD, NINDS, Center for Scientific Review at NIH and as a consultant to the FDA. In 2005, Dr. Milgrom was appointed the SAAD Visiting Professor of Pain and Anxiety Control at the King's College Dental Institute, University of London, UK for a six-year term. In 2008 he was awarded the degree of Doctor Honoris Causa from the University of Bergen, Norway in recognition of his work in social and behavioral dentistry. In 2012, he received the University of California, San Francisco Dental Alumni Gold Medal for his contributions to Dentistry. In 2012 he was also awarded the Norton Ross Award for Excellence in Clinical Research by the American Dental Association. In 2013, he was appointed to the Council of Scientific Affairs of the American Dental Association. In 2014, he received the Irwin M. Mandel Distinguished Mentor Award from the IADR. In 2015, he served as HMDP Expert in Dental Public Health for the Singapore Ministry of Health. Dr. Milgrom received his DDS from the University of California, San Francisco in 1972 and had a previous position at the National Academy of Sciences, Engineering, and Medicine. In the last few years, Dr. Milgrom has spoken to dental associations in Argentina, Colombia, Peru, Philippines, and USA and at major universities in USA and abroad.

What does it take to run successful clinical trials across borders? Tune in as Chris Boone (Group VP, Research, Health & Life Sciences at Oracle) and Alicia Baker McDowell (VP & Head of Global Regulatory Strategy at Fortrea) explore the shift from transactional outsourcing to truly co-created partnerships.They discuss how sponsors, CROs, and tech partners are redefining collaboration, tackling data fragmentation, and striking the right balance between global consistency and local execution to deliver more effective clinical trials worldwide.

We discuss long term results of faricimab treatment of DME, with the first author of the Ophthalmology article on the results of Rhone-X trial, Dr. Veeral Sheth, Director of Clinical Research at University Retina in Chicago.

Learn how ashwagandha, rhodiola, ginseng, and black seed oil normalize stress responses without side effects—plus what science says about ThymoQuin. #Adaptogens #CortisolControl #NaturalEnergy

Luke's LinkedIn: https://www.linkedin.com/in/luke-snedaker-3511b18a/My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

Send us Fan MailPost-thrombotic syndrome (PTS) affects up to half of patients following deep vein thrombosis and can significantly impair quality of life. Yet treatment options have historically been limited.In this episode of CLOT Conversations, David Airdrie and Dr. Jameel Abdulrehman speak with Dr. Susan Kahn about the recently published C-TRACT trial in The New England Journal of Medicine.The trial evaluated whether endovascular therapy, including iliac vein stenting, could improve outcomes for patients with moderate-to-severe post-thrombotic syndrome and iliac vein obstruction.Dr. Kahn discusses the rationale behind the study, key findings related to symptom burden and quality of life, the increased bleeding risk observed with intervention, practical patient selection considerations, and the unanswered questions that remain regarding long-term management after venous stenting.This episode provides clinicians with practical insights into one of the most important recent studies in the management of post-thrombotic syndrome.Reference:Vedantham S, Kahn SR, Marston WA, Weinberg I, Sista AK, Magnuson EA, Cohen DJ, Wasan SM, Razavi MK, Goldhaber SZ, Sanfilippo KM. Endovascular Therapy for Post-Thrombotic Syndrome—A Randomized Trial. New England Journal of Medicine. 2026 Apr 13.https://www.nejm.org/doi/abs/10.1056/NEJMoa2519001Support the showhttps://thrombosiscanada.caRegister today for our upcoming conference on November 7, 2026 in Montreal at https://thrombosiscanada.ca/2026ConferenceTake a look at our healthcare professional and patient resources, videos and publications on thrombosis from the expert members of Thrombosis Canada

At the 2025 AAHKS Annual Meeting, our hosts William B. Kurtz, MD and Matthew W. Bullock, DO sat with Matthew S. Hepinstall, MD, FAAOS and Kyle L. McCormick, MD, the 2025 Clinical Research Award winners to discuss their study “Maximizing Bearing Diameter Markedly Lowers Dislocations in Primary Total Hip Arthroplasty” that was presented at the AAHKS Annual Meeting.   Prevention of dislocation is a topic of interest for Drs. Hepinstall and McCormick which is what prompted this study that consisted of over 8,000 patients who underwent fixed-bearing THA. Because modern polyethylene allows larger bearings in fixed-bearing THA, stability benefits of fully maximizing bearing diameter (e.g. 36-mm in 48/50-mm cups) are not well established. Drs. Hepinstall and McCormick discussed on the podcast the number of dislocations in the study with patients with maximized bearing diameters and how certain variables such as age, sex and body-mass index help to protect against dislocation.  For more on how fully maximizing bearing diameter reduced dislocation odds in primary fixed-bearing THA, listen to the full podcast. Don’t forget to subscribe and thanks for listening to AAHKS Amplified! In This Episode:Matthew W. Bullock, DO Matthew S. Hepinstall, MD, FAAOSWilliam B. Kurtz, MDKyle L. McCormick, MD  The post The 2025 AAHKS Clinical Research Award Winner first appeared on AAHKS.

My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

Artificial intelligence is rapidly reshaping the landscape of rare disease research -- but how close are we to realizing its full potential? In this episode, Tanya Binette (Director of Therapeutic Expertise, Rare Disease at ICON plc) and Roz Round (SVP of Operational Strategy, Patient and Site Engagement at Precision for Medicine) explore how AI is being applied across the rare disease clinical trial lifecycle, from drug discovery and protocol design to patient identification and engagement.The discussion highlights both the promise and complexity of using AI in a research space defined by small patient populations, fragmented data, and unique ethical considerations. Guests emphasize the importance of patient trust, regulatory alignment, and responsible innovation, while also identifying opportunities to accelerate trials, improve access, and empower patients through AI-enabled tools.

My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

How This Is Building Me, hosted by world-renowned oncologist D. Ross Camidge, MD, PhD, is a podcast focused on the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life's experiences.In this episode, Dr Camidge sat down with Karen L. Reckamp, MD, director of Medical Oncology, associate director of Clinical Research, and the medical oncology director of the Lung Institute at Cedars Sinai in Los Angeles, California.Drs Camidge and Reckamp discussed Dr Reckamp's journey as an oncology specialist and now a caregiver for her husband, who has cancer. Reckamp's career was inspired by her family's history with BRCA-related cancers. She pursued an academic path that eventually led her to Los Angeles, where she became a leader in thoracic oncology during an era of genomic breakthroughs.In late 2024, her husband, a fellow oncologist, was diagnosed with pancreatic cancer shortly after a clear annual scan. Reckamp described the jarring transition of receiving the diagnosis and the ensuing emotions balanced with medical pragmatism. Bob underwent intensive treatments that have affected his physical health and daily life.Reckamp offered a candid look at the dual role of a physician-caregiver. She continues to work, however, her husband's cancer diagnosis has changed her practice. Now, she is more sensitive to chemotherapy toxicities in her patients that she might have previously minimized. She also highlighted the invisible load of caregivers who must manage their own emotions and remain available for patient needs.Ultimately, Reckamp emphasized the necessity of a support network, crediting their long-time nanny and overall community with maintaining her family's stability. By allowing different people to hold different pieces of the emotional burden, Reckamp shared that her family is finding a way to move forward amidst the uncertainty of this cancer diagnosis.

Generative AI and other technologies are transforming clinical research and trials. Find out how it's done.     The clinical trials sector is risk-averse, heavily regulated, and not often thought of as a technology first-mover. How is Merck changing that perception by using AI to improve insights, innovation, and operations?     Join Steve Odland and guest Jennifer Sheller, senior vice president and head of global clinical trial operations at Merck, to find out how the company is using AI for clinical research and clinical trials, why "human in the loop" remains essential, and how Merck thinks about the ethical, safety, and privacy considerations of digital health.     For more from The Conference Board:  How AI Can Help Remedy the US Health Care Workforce Crisis  Health Care Workforce Policy Summit: Insight Summary  Navigating the Health Care Landscape in 2026 

Site feasibility remains a critical yet complex component of clinical trial startup. In this episode, listen as Andrea Bastek (VP, Market Strategy at Florence Healthcare), Christine Senn (SVP, Site-Sponsor Innovation at Advarra), and Ashley Davidson (SVP, Head of Product at Advarra) unpack the persistent challenges in feasibility -- from manual, time-intensive processes and data trust gaps to misaligned timelines and limited transparency between stakeholders.The conversation explores how collaboration, smarter process design, and emerging technologies like AI and real-time data integration can reduce burden on sites and improve study startup timelines. Guests also share practical recommendations, including simplifying CDA processes, improving communication between sponsors and sites, and leveraging data more effectively to move forward toward a more efficient and connected feasibility model.Resources:- Advarra CDA Template - Advarra Site ID Feasibility Solution- Paper from Florence Healthcare's Site Enablement League

Send us Fan MailWhen T.J. Sharpe was diagnosed with stage 4 melanoma at just 37 years old, the statistics were devastating. With a newborn son, a two-year-old daughter, and limited treatment options available at the time, he faced a life-changing decision: pursue standard chemotherapy or take a chance on early immunotherapy clinical trials.In this powerful episode of the MedEvidence Podcast, cardiologist and medical researcher Michael Koren sits down with T.J. to discuss his remarkable journey from cancer recurrence and uncertainty to becoming a long-term survivor through groundbreaking clinical research.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

What does "patient-centricity" actually look like in practice, and why does it still fall short? In this episode, Stacy Hurt (Chief Patient Officer at Parexel) and Alicia Staley (Chief Patient Officer at Medidata) bring both lived experience and industry insight to a powerful discussion on the gaps between intention and reality in clinical research. They unpack the emotional and logistical challenges patients face, from navigating fragmented systems to feeling dismissed by well-meaning but unhelpful messaging. The discussion highlights the need for systemic thinking, stronger partnerships with advocacy communities, and greater adoption of patient leadership roles. With real-world examples and a forward-looking perspective, this episode offers a roadmap for turning patient-centricity into tangible change.

Send us Fan MailPregnenolone, a neurosteroid derived from cholesterol, affects brain activity and shows promise for treating mood and substance abuse disorders.TOPICS DISCUSSED:Steroid Biosynthesis: Cholesterol converted to pregnenolone, the precursor for all steroid hormones including cortisol, aldosterone, and sex hormones.Corticosteroids: Synthetic versions like prednisone primarily target glucocorticoid receptors for anti-inflammatory uses but can impact mood and cognition.Pregnenolone Mechanisms: Positive allosteric modulator of NMDA receptors for cognition and negative allosteric modulator of CB1 cannabinoid receptors.Allopregnanolone: GABAergic derivative of pregnenolone; its IV form Brexanolone is FDA-approved for postpartum depression.Clinical Trials: Pregnenolone at 100-500 mg improved depressive symptoms in placebo-controlled studies of bipolar disorder patients.Cannabis Interaction: THC robustly induces brain pregnenolone production; supplementation may reduce cannabis and alcohol use.Corticosteroid Brain Impact: Prednisone use associated with smaller hippocampal volumes and memory deficits.ABOUT THE GUEST: Sherwood Brown, MD, PhD is Vice Chair for Clinical Research in the Department of Psychiatry at the University of Texas Southwestern Medical Center in Dallas. With a background in chemistry, his research focuses on steroids and comorbidities in people with mood disorders.RELATED EPISODE:M&M 124: Hormonal Contraception, Sex Hormones, Menstruation, Pregnancy, Puberty, Estrogens, Androgens, Effects of Birth Control on Cognition | Adriene BeltzSupport the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts

My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

In this episode of The Clinical Research Coach, host Leanne Woehlke sits down with Angela Radcliffe for a powerful conversation about empathy, innovation, and why the future of clinical research must remain deeply human.Angela shares the personal experiences that shaped her passion for healthcare and clinical research, including the profound impact clinical trials had on her own family. Together, Leanne and Angela explore how the industry can embrace AI and emerging technologies without losing the trust, compassion, and human connection patients need most.From patient experience and purpose-driven leadership to the balance between technology and empathy, this episode is a reminder that innovation works best when it serves people first.If you care about the future of clinical research, patient trust, and keeping humanity at the center of healthcare innovation, this conversation is one you won't want to miss.Learn More:About Angela:Angela Radcliffe is a dynamic speaker, best-selling author, and impact influencer who advocates for teaching children (ages 8-14) health, data and AI literacy to provide them with the necessary skills and knowledge to thrive in a data-driven world. She's the author of “Quantum Kids Guardians of AI”, an activity book that introduces elementary and middle school students to AI fundamentals through seven engaging missions. The book weaves concepts like neural networks, large language models, data ethics, and prompt engineering into relatable stories about school, social media, and robotics. It empowers young readers to: - Apply AI knowledge to homework and hobbies- Navigate Internet safety - Understand technology's role in addressing societal challenges- Make informed decisions about health and personal data protection.With 20+ years of experience, Angela drives progress in medical research, healthcare marketing, and healthcare data and artificial intelligence. She understands the intricate interplay of trust, value, and risk in unleashing power from petabytes of data. Frequently at the helm of global endeavors, including as Head of Digital Performance Improvement and Innovation for Research and Early Development IT, Head of Enterprise Digital Strategy Innovation, and Head of Enterprise Data Governance at Bristol Myers Squibb, she's orchestrated transitions from molecular concepts to market-ready solutions and from boardroom strategies to tangible implementations that transform customers into champions. Over the years, Angela has worked closely with thousands of patients participating in clinical trials, partnered seamlessly with tech luminaries and stood shoulder-to-shoulder with industry peers with a single focus: pushing, often pulling, clinical research and healthcare forward. Angela's compelling thought leadership combines technical insights on AI's growing impact with her personal stories of overcoming adversity. Her experiences such as growing up poor, leaving an abusive spouse, losing her 21-year-old brother to an undiagnosed heart condition, and raising a neurodivergent daughter fuel her mission to advance health, data and AI literacy. This unique background and her stellar communications and interpersonal skills make her a sought-after speaker for podcasts and with life sciences, patient education, mental health, data privacy, teacher and parent organizations.Connect with Angela Radcliffe on LinkedIn:https://www.linkedin.com/in/angela-radcliffe-2560256/Angela's Website:https://intelligenceapplied.ai/Angela's Books:The Five Laws of Applied Intelligence: Why Your Humanity Is Your Superpower and How to Use It to Win in a World of Machines Quantum Kids Guardians of AI: Story Quest and Activity Book

Southern Remedy Healthy and Fit is hosted by Josie Bidwell, Professor of Preventive Medicine and Nurse Practitioner at UMMC. If you have a question for Josie, you can email fit@mpbonline.org. It this episode, Josie talks about clinical research and studies with Dr. Matthew Kutcher, a trauma and acute care surgeon at UMMC and Chris Moore, Director of Clinical Research at UMMC. If you enjoy listening to this podcast, please consider contributing to MPB. https://donate.mpbfoundation.org/mspb/podcast. Hosted on Acast. See acast.com/privacy for more information.

What happens when clinical trial sites are given the resources and autonomy to determine precisely what their site needs to be successful? In this episode, participants from the ACRO Site Grants Program share how targeted funding helped them tackle real-world barriers to clinical trial access and diversity. From community-based outreach and patient education, to internal infrastructure and staffing, these sites implemented tailored solutions designed to meet the unique needs of their communities. Along the way, they encountered challenges, adapted their approaches, and uncovered valuable lessons about trust-building, flexibility, and long-term engagement.This conversation highlights how even small investments can drive meaningful change at the site level, and what the broader industry can learn from these experiences.

My Free tools for sites and researchers: https://coordinare.co/My substack FREE: https://substack.com/@dansfera1?r=27gh4e&utm_medium=ios&utm_source=profileInato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRC Academy: http://www.TheCRCacademy.comMy TikTok: DanSfera

Artificial intelligence is reshaping every stage of drug development, but unlocking its full potential requires more than technology alone. In this episode, Clay Alspach (Executive Director, ACRO) Raja Shankar (VP of Machine Learning at IQVIA), and Andrew Mackinnon (SVP & Executive General Manager at Medable) come together to examine how policy, regulation, and global collaboration will shape the future of AI in clinical trials.From breaking down data silos to addressing regulatory uncertainty and enabling a “try first” mindset, the discussion highlights both the opportunities and the complexities ahead. With insights on patient impact, site experience, and the next wave of innovation, this episode offers a roadmap for advancing AI in a way that is both responsible and transformative. 

Why do qualified candidates apply to role after role in clinical research and never hear back? In this episode of the Clinical Trial Podcast, we unpack what's really happening behind the scenes in the hiring process. Getting hired isn't just about your technical skills. It's about how hiring managers assess risk, how recruiters decide who to champion, and who actually gets attention versus who gets ignored. Kunal Sampat is joined by Giovanni Lauricella, Co-Founder and CEO of Lifeblood, an executive search firm specializing in MedTech. With over 15 years of experience placing board members, C-suite leaders, and cross-functional talent globally, Giovanni brings a unique perspective from inside the hiring process. In this episode, you'll learn: Why strong candidates get filtered out before interviews What hiring managers are actually looking for How recruiters decide who to advocate for What it really takes to break into and advance in clinical research If you've ever felt stuck in your job search or wondered why the process feels like a black box, this conversation will give you a clearer understanding of how hiring decisions are actually made.

In this episode of Disruption/Interruption, host KJ sits down with Ome Ogbru, PharmD, CEO and founder of AINGENS, to tackle a decades-old problem hiding in plain sight: life sciences runs on groundbreaking science, but is buried in broken processes. After 20+ years as a clinician, professor, and pharmaceutical executive, Ome reached a breaking point, and instead of finding a new job, he built a new company. He shares how generative AI, used responsibly and strategically, can finally give researchers their time back, cut through misinformation, and help the right information reach the right people faster. Four Key Takeaways: The scientific content workflow is fundamentally broken [4:15] -- Research teams are so resource-strapped that PhDs spend their time managing IT systems instead of doing science. Procuring a software solution could take one to two years and often didn't even solve the right problem. Generative AI isn't the magic wand, it's how you use it [20:01] -- When Ome first tested ChatGPT on biotech content and got poor results, he had a revelation: the tool wasn't the problem. The problem was not knowing how to use it. Pairing AI with deep domain expertise and proper workflows is where the real power lies. The human expert must remain in the driver's seat [32:30] -- AINGENS' platform (MACG) is built so the professional is in control. The AI handles the time-consuming, mundane tasks like literature search, drafting, and formatting, while the expert applies regulatory knowledge, judgment, and guardrails. Misinformation in life sciences is a public health problem [35:49] -- Misinformation travels faster than accurate data. Ome's vision is for generative AI to help industry proactively get accurate, personalized scientific information to the people who need it, patients, clinicians, and researchers alike, before the noise wins. Quote of the Show (35:41):"Misinformation flies faster than correct information." -- Ome Ogbru Join our Anti-PR newsletter where we’re keeping a watchful and clever eye on PR trends, PR fails, and interesting news in tech so you don't have to. You're welcome. Want PR that actually matters? Get 30 minutes of expert advice in a fast-paced, zero-nonsense session from Karla Jo Helms, a veteran Crisis PR and Anti-PR Strategist who knows how to tell your story in the best possible light and get the exposure you need to disrupt your industry. Click here to book your call: https://info.jotopr.com/free-anti-pr-eval Ways to connect with Ome Ogbru:LinkedIn: https://www.linkedin.com/in/ome-ogbru-pharmd/Company Website: http://www.aingens.com How to get more Disruption/Interruption: Amazon Music - https://music.amazon.com/podcasts/eccda84d-4d5b-4c52-ba54-7fd8af3cbe87/disruption-interruption Apple Podcast - https://podcasts.apple.com/us/podcast/disruption-interruption/id1581985755 Spotify - https://open.spotify.com/show/6yGSwcSp8J354awJkCmJlDSee omnystudio.com/listener for privacy information.

Theo Jaffee and Gabriel Dickinson speak with Cremieux about China's rapid rise to the top of global clinical trial output. They discuss the regulatory reforms that accelerated China's progress, the surge in novel drug development, and what the US would need to change to stay competitive in biomedical innovation.   Resources: Follow Cremieux on X: https://x.com/cremieuxrecueil Follow Theo on X: https://x.com/theojaffee Follow Gabriel on X: https://x.com/gbrl_dick   Stay Updated:Find a16z on YouTube: YouTubeFind a16z on XFind a16z on LinkedInListen to the a16z Show on SpotifyListen to the a16z Show on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Tracy Morgan is a psychoanalyst in private practice in NYC seeing individuals, couples and groups. She is a member of the faculty at CMPS, a founding member of Das Unbehagen and the founding editor of the award winning podcast New Books in Psychoanalysis. She has published on a variety of subjects ranging from Gay and African American history, social movement theory, and psychoanalysis. Her most recent publication, Must We Drown in the Wake? Notes on Addressing Racism at Psychoanalytic Institutes was recently published in the journal Group. And the essay was nominated for a Gradiva Award for best article in the field in 2025. Ashis Roy, PhD, is a psychoanalyst and scholar affiliated with the Indian Psychoanalytical Society (Kolkata) and the International Psychoanalytical Association (London). His clinical practice serves adults, young adults, and couples, informed by over a decade of pedagogical and institutional leadership. Previously, as a faculty member at the Centre of Psychotherapy and Clinical Research, Ambedkar University, Dr. Roy was instrumental in institutional development and the clinical training of psychoanalytic psychotherapists. Currently, he serves on the faculty of the China-American Psychoanalytic Alliance (CAPA). His research resides at the intersection of clinical praxis and cultural psychoanalysis, with a specialized focus on the application of psychoanalytic frameworks to Asian and South Asian sociocultural contexts. An active contributor to international scholarly dialogue, he hosts psychoanalytic segments for the New Books Network. Dr. Roy is the author of the book Intimacy in Alienation: A Psychoanalytic Study of Hindu-Muslim Relationships (Yoda Press, 2024), which examines the psychodynamic complexities of inter-communal intimacy. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/psychoanalysis

Get My Brand Masterlist: https://drchristiangonzalez.com/best-brands-form-2-2/ → Shop all my verified, tested and preferred wellness products - includes most up to date brands: https://theswellscore.com/pages/drg Episode Description You started creatine, felt bloated, broke out, noticed your hair shedding — and then wondered if you were crazy. You weren't. But you were missing something important. Creatine is one of the most well-researched supplements in history. But almost all of that research was done on men. And when the wellness world rebranded it as a brain and energy supplement for women, nobody stopped to talk about hormones, cycle phases, gut tolerance, or the environment your body is actually in when you start taking it. Dr. G breaks down exactly what's happening — and who creatine is actually for. In this episode, you'll learn:  • Why creatine causes bloating, breakouts, and hair shedding in some women — and what it's actually telling you about your physiology  • The three groups of women when it comes to creatine: who benefits, who needs a modified approach, and who should skip it entirely for now  • What has to be in place before creatine can actually work — and why taking it on top of poor sleep, undereating, or overtraining almost always backfires If you've tried creatine and felt worse, or you're wondering if it's worth trying — this is the episode that gives you a real answer. Timestamps: 0:00 - Intro 1:00 - Why Creatine Crossed Over Into Women's Wellness (And What the Research Actually Says) 2:32 - How Creatine Actually Works in the Female Body 4:03 - What the Clinical Research on Women and Creatine Really Shows 5:28 - Bloating, Breakouts & Hair Shedding: What's Actually Causing It 7:04 - Why Your Physiology May Not Match What Creatine Is Asking of You 10:40 - The Three Groups: Who Should Take It, Who Should Be Careful, Who Should Skip It 12:33 - Final Word: Always Talk to a Professional First Learn more about your ad choices. Visit megaphone.fm/adchoices

Natalie Crawford, MD is board certified in both Obstetrics and Gynecology and Reproductive Endocrinology and Infertility and is co-founder of Fora Fertility, a boutique fertility practice in Austin, Texas. Dr. Crawford is CEO and co-founder of Pinnacle, a professional network for women in medicine. She completed her undergraduate at Auburn University obtaining a degree in Nutrition Science, Medical School at UTMB, OBGYN Residency at UTSW, and REI Fellowship at UNC, concurrently obtaining a Master of Science in Clinical Research. Dr. Crawford is a digital health educator on social media, YouTube, and hosts the podcast  “As a Woman” with over 6 million downloads. Her debut book, “The Fertility Formula”, will be released by Penguin Random House.   Follow Dr. Crawford on Instagram at @nataliecrawfordmd and check out her book, The Fertility Formula.   Related Episodes: Ep 155 - Dr. Marguerite Duane on FACTS about Fertility Ep 314 - The Fertility Crisis + Support for Couples with Ronit Menashe + Vida Delrahim   If you like this episode, please subscribe to Pursuing Health on iTunes and give it a rating or share your feedback on social media using the hashtag #PursuingHealth. I look forward to bringing you future episodes with inspiring individuals and ideas about health.   Disclaimer: This podcast is for general information only, and does not provide medical advice.  I recommend that you seek assistance from your personal physician for any health conditions or concerns.

I'm thrilled to connect with Dr. Natalie Crawford today. She's a double-board-certified fertility doctor and the author of The Fertility Formula. Unlike most other physicians, she blends lifestyle and functional medicine with science-based facts, aiming to help women conceive and understand their bodies. While this conversation may not feel fully aligned with the perimenopause and menopause transition, I encourage you to listen with an open mind to what Natalie shares about hormones. In our discussion, we explore fertility as a vital sign, the impact of infertility, and why one in six women experiences infertility. We break down ovarian reserve and the realities of aging. We also cover specific labs that can help assess ovarian reserve and overall health. We explain DOR and POI, the overlap between fertility and perimenopause, and why the ovaries can behave like a “cranky toddler” in perimenopause. Finally, we dive into the role of the gut microbiome in estrogen metabolism and inflammation, and discuss IVF, egg freezing, modern reproductive options, lifestyle influences, and a series of rapid-fire questions. Dr. Crawford's book, The Fertility Formula, is a must-read for women of all ages. It contains many valuable insights, and I love the way she blends an integrative approach with an allopathic approach for her patients. IN THIS EPISODE, YOU WILL LEARN: How fertility serves as a health marker that reflects a woman's hormonal, cellular, and metabolic health The role of inflammation in infertility Dr. Crawford clarifies ovarian reserve, highlighting the importance of understanding egg quality and quantity. Why AMH testing is the most informative first step for women concerned about their fertility Dr. Crawford outlines three factors that can cause missed or irregular periods. The importance of tracking ovulation and understanding the body's signals during perimenopause Inflammation and aging can disrupt chromosome alignment and impair embryo development. How poor estrogen clearance and gut microbiome imbalances disrupt brain-ovary signaling and ovulation timing The link between sleep deprivation and low sperm counts, and how stress and lack of muscle mass can drive insulin resistance and inflammation Why sleep, muscle mass, and stress reduction are all essential for fertility It's essential to approach fertility proactively, and to know how to do that. Bio: Natalie Crawford Natalie Crawford, MD, is board-certified in both Obstetrics and Gynecology and Reproductive Endocrinology and Infertility and is co-founder of Fora Fertility, a boutique fertility practice in Austin, Texas. Dr. Crawford is CEO and co-founder of Pinnacle, a professional network for women in medicine. She completed her undergraduate degree at Auburn University, obtaining a degree in Nutrition Science, Medical School at UTMB, OBGYN Residency at UTSW, and REI Fellowship at UNC, concurrently obtaining a Master of Science in Clinical Research. Dr. Crawford is a digital health educator on social media, YouTube, and hosts the podcast  “As a Woman” with over 6 million downloads. Her debut book, “The Fertility Formula”, will be released by Penguin Random House.  Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Natalie Crawford On her website On social media: @NatalieCrawfordMD Dr. Crawford's book, The Fertility Formula, is available here.

Premier League soccer player Thomas Robson-Kanu turned a career-threatening injury into a mission—building The Turmeric Co., a raw functional beverage brand now reaching customers across 15,000 UK retail locations. For more on The Turmeric Co and show notes click here Subscribe and watch Shopify Masters on YouTube!Sign up for your FREE Shopify Trial here.