Podcasts about Hypothesis

Matt and Nic are back with another week of news and deals. In this episode:  Are OpenAI and Anthropic reenacting the Fat Protocol Hypothesis Will AI agents cause bank runs optimizing bank balances for yield? If the AI complex bursts does it take down VC? Our tribute to Hester Peirce as she retires from the SEC The SEC and CFTC publish crypto FAQs Vitalik lays out his vision for Ethereum in 2030 Quantum progress is accelerating Illinois delays their crypto transaction tax  Is San Francisco better than it was? 

Roger Seheult, MD of MedCram deep dives into infrared light interacting with mitochondria. (This video was recorded on September 26th, 2026) Roger Seheult, MD is the co-founder and lead professor at: www.medcram.com He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine. MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS: MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested. MEDIA CONTACT:  Media Contact: customers@medcram.com Media contact info: https://www.medcram.com/pages/media-contact Video Produced by Kyle Allred Edited by Daphne Sprinkle of Sprinkle Media Consulting, LLC FOLLOW US ON SOCIAL MEDIA: Facebook:  www.facebook.com/MedCram Twitter/X: www.twitter.com/MedCramVideos Instagram: www.instagram.com/medcram DISCLAIMER: MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

Steve Andrews presents an “extension to the cosmic ray hypothesis” for climate change, building on Svensmark and Shaviv's idea that galactic cosmic rays influence low clouds and cooling, modulated by solar and Earth magnetic fields. Using UAH satellite temperature anomalies (1979–present), CERES, and Oulu neutron counts, he claims monthly warming-rate peaks occur near equinoxes, varies by region, and differs over land vs ocean. He links this to the Russell–McPherron effect: equinox magnetic alignment increases geomagnetic storms, solar-energy input heats and expands the thermosphere, shifting where cosmic-ray energy is dissipated, altering cloud height (higher clouds warming). He argues CO2-driven warming is unsupported, cites CERN CLOUD evidence for cloud nuclei, and suggests declining geomagnetic strength may matter.00:00 Steve Returns and Topic00:25 Feynman Quotes and Credentials01:19 Cosmic Ray Climate Basics04:13 Heliosphere and Magnetosphere07:50 Evidence and Correlations13:28 New Solar Oscillations16:43 Why Satellite Data Matters20:33 Monthly Warming Rate Method22:26 Equinox Peaks in Warming25:58 Exceptions Canada Australia29:33 Land Minus Ocean Signal32:05 Geomagnetic Storm Explanation35:59 Auroras and Equinox Effect36:20 Cloud Height Climate Lever36:47 Thermosphere Heating Mechanism39:20 Thermosphere Expansion Evidence40:08 Tropics and Cosmic Ray Patterns42:14 Climate Impact Summary43:40 Cloud Data and Correlations45:06 Challenges and Magnetic Field49:48 Solar Flux and Altitude Signals53:22 QBO Link to Solar Cycles56:38 Satellite Cloud Height Trends59:12 Long Records and Big Claims01:03:43 Renewables Cost Anecdote01:05:47 Q and A CERN and Aerosols01:11:39 Closing RemarksStephen Andrews Substack: https://substack.com/@stephen938=========Slides, summaries, references, and transcripts of my podcasts: https://tomn.substack.com/p/podcast-summariesMy Linktree: https://linktr.ee/tomanelson1

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Bret Weinstein speaks with John Cullen on the subject of the unanswered questions surrounding the assassination of Charlie Kirk and the 2017 Las Vegas shooting.Find John Cullen on X at https://x.com/I_Am_JohnCullen and on Patreon at https://www.patreon.com/cw/IAMJOHNCULLEN. *****Sponsors:Lovebird: Delicious, nutritious cereal made with real ingredients. Go to http://lovebirdfoods.com/darkhorse and use code DARKHORSE for 25% off your first order.Mars Men: Natural testosterone booster supplement. For a limited time, our listeners get 50% off for life, free shipping, and 3 free gifts from Mars Men at http://Mengotomars.com.*****Join DarkHorse on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.comCheck out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://www.darkhorsestore.orgMusic: "Marble Machine" by WintergatanThis track can be downloaded for free at www.wintergatan.netFree License to use this track in your video can be downloaded at www.wintergatan.net*****Mentioned on this episode:- Was Charlie Kirk Killed With a Drone? Viva Frei and Jimmy Dore on DarkHorse: https://www.youtube.com/watch?v=TO76X9CFhUI- How Many Shooters? John Cullen on the Trump Assassination Attempt (July 2024): https://www.youtube.com/watch?v=0hKuo2qW6uE- Multiple Shooters? John Cullen & Clay Martin (TPC #1,538): https://rumble.com/v592bhg-multiple-shooters-john-cullen-and-clay-martin-tpc-1538.html*****Timestamps:00:00:00 Can You Trust a Man With a Pen Name?00:01:39 Tyler Robinson, Acting Alone?00:03:42 Sponsor: Lovebird Cereal00:05:33 Why John Cullen Is Irrelevant00:22:10 Sponsor: Mars Men00:23:07 A Pentagon Spy Plane at UVU00:32:24 Back 25 Minutes After the Shot00:57:31 The Drones Nobody Wants to Explain01:10:42 Bird of Prey: A Rifle That Flies01:17:55 The Round Left on the Roof01:37:34 Why Was There No Exit Wound?01:43:27 Butler and the Spiral of Silence01:50:42 Wouldn't Someone Have Seen It?01:59:37 Las Vegas: No Shots From the Window02:05:31 Was the Real Target MBS?02:19:47 Three Women, a Minivan, 24 Guns02:27:35 Flushing Out the Crown Prince02:39:46 Who Broke the Window?02:47:01 The Deadliest Gunman in History?Support the show

Le huit clos policier "Le problème final" est à découvrir sur Netflix . Sur Prime vidéo, on s'intéresse à la comédie romantique "The love Hypothesis"

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Just a Hypothesis: Case Formulation and Treatment Planning for Real-World Therapy - An Interview with Nikki Rubin, PsyD Nikki Rubin, PsyD on behavioral case formulation, treatment planning, and clinical decision-making for therapists. Curt and Katie talk with Nikki Rubin, PsyD, licensed clinical psychologist and co-founder and COO of MindScience Collective, about what case formulation looks like when it is built for real-world therapy instead of for a graduate school assignment. Most of us learned case conceptualization as an exhaustive academic exercise and then quietly stopped doing it. Nikki describes behavioral case formulation as one large working hypothesis: a holistic read on seven areas of a client's functioning that tells you what you are targeting, why, and what to do when treatment stalls. Formulation and treatment planning are inseparable, and neither one requires you to be a CBT therapist. Nikki walks through the seven components (drawn from the work of Jacqueline Persons, PhD), the traps clinicians fall into, how to operationalize target behaviors, why structure creates flexibility rather than rigidity, and what a scaled-down formulation looks like under session limits or in crisis work. A useful conversation for therapists across orientations, for supervisors and educators, and for anyone who has felt unsure where a treatment is going. In this episode, we discuss: - The three traps therapists fall into with case formulation - The seven areas of a behavioral case formulation, and why they work across orientations - Why a formulation is a set of hypotheses to test, not conclusions to defend - How to operationalize target behaviors so you can track them in session - Why covert behaviors (worry, rumination, suppression) belong in your formulation - How to scale a formulation down when you are short on time or sessions Timestamps: - 04:16 - The traps therapists fall into with case formulation - 08:56 - The seven areas of a behavioral case formulation - 15:05 - What case formulation looks like in real time - 17:59 - From formulation to treatment planning and target behaviors - 21:04 - Does structure make case formulation rigid? - 29:35 - Case formulation under time pressure and session limits - 36:17 - Where to start if you have not done this since graduate school Guest Bio: Nikki Rubin, Psy.D. is a licensed clinical psychologist specializing in Acceptance and Commitment Therapy (ACT) and other 3rd wave cognitive behavioral therapies. She is an Associate Clinical Professor at UCLA, where she trains doctoral students in ACT, and co-founder and COO of MindScience Collective, a continuing education company for clinicians. Learn more at mindsciencecollective.com and drnikkirubin.com. Special offer for Modern Therapist listeners: use code MTSG10 for 10% off at mindsciencecollective.com. Full show notes and transcript: mtsgpodcast.com Join the Modern Therapist Community Patreon: https://www.patreon.com/c/mtsgpodcast Facebook Group: https://www.facebook.com/groups/therapyreimagined Modern Therapist's Survival Guide Creative Credits Voice Over by DW McCann: https://www.facebook.com/McCannDW/ Music by Crystal Grooms Mangano: https://groomsymusic.com/

Did Life Arrive From Space? The Murchison Meteorite & LithopanspermiaOn September 28, 1969, a blazing fireball exploded over Murchison, Australia, showering the countryside with roughly 100 kilograms of ancient extraterrestrial rock. Coming right around the time laboratories worldwide were outfitted with state-of-the-art equipment for Apollo 11 moon samples, scientists immediately analyzed the freshly fallen meteorite and discovered a startling revelation: it contained dozens of amino acids—the fundamental building blocks of life. Curiously, alongside the 20 standard amino acids used by terrestrial biology, the rock contained dozens of completely alien amino acids unknown to life on Earth. This proved that space is capable of producing intricate organic building blocks through abiotic processes long before planets even form, raising a profound question: could the seeds of life itself travel across the cosmos?This hypothesis, known as lithopanspermia, challenges our common assumptions about the fragility of life in space. Physical evidence confirms that rocks are routinely ejected from planets like Mars by asteroid impacts and eventually land on Earth. Furthermore, shock experiments and extreme organisms—such as Deinococcus radiodurans and tardigrades—demonstrate that microbes can survive the extreme pressures of ejection, cosmic radiation, the vacuum of space, and even atmospheric entry, shielded inside insulating rock. While we have not yet found definitive proof of alien life, early planetary conditions raise the eerie possibility that life began on a wet, ancient Mars and seeded a young Earth.

There's a question that's been circulating widely these days. It's in the clinic, it's in the news, and it's on patients' minds. Why do allergies appear to be increasing? Enter the epithelial barrier hypothesis. This is a developing theory that sees a connection between the ‘atopic march' and the breakdown of the epithelial barrier.On today's episode we speak with Professor Cezmi Akdis. Professor Akdis is a director of the Swiss Institute of Allergy and Asthma Research in Davos and professor at the University of Zurich. His research has been instrumental in the development of the epithelial barrier hypothesis.We cover:What epithelial barrier integrity looks like when it is workingWhat epithelial dysfunction looks likeEvidence for epithelial barrier breakdown Connection between epithelial barrier dysfunction and the atopic marchEnvironmental factors common to Western societies, such as detergents, processed food and air pollution, that impact the epithelial barrierOpportunities for early intervention to repair the barrierIt can seem like the sources of epithelial dysfunction are just about everywhere but the solution may begin at home.Have an idea for the show or a comment, send us a text!Visit the Canadian Society of Allergy and Clinical ImmunologyFind an allergist using our helpful toolFind Dr. Hanna on X, previously Twitter, @PedsAllergyDoc or CSACI @CSACI_caThe Allergist is produced for CSACI by PodCraft Productions

What if the most famous bodybuilding supplement in history was actually meant for your brain? For over 30 years, we've lived in a reality where creatine belongs exclusively to plastic shaker bottles, gym bro subculture, and building big muscles. But behind the scientific shadows, a parallel market universe has existed since the very beginning. In this episode, I'll dive deep into the collapsing walls between sports nutrition and cognitive longevity. From early 1990s constraints that commercially suppressed "cognitive creatine" to the modern epidemic of burnout, stress, and sleep deprivation...the macro dynamics have completely flipped. Discover how forward-thinking wellness CPG brands are leveraging new ingredient technology to charge premium prices for creatine, why combining creatine with nootropics creates a "dual-engine" for focus, and how food scientists are racing to solve the "golden goose" stability puzzle. Once unlocked, creatine is escaping the pharmacy aisle to become a baseline upgrade in mainstream functional drinks and the global food matrix. The "gym bro" era was just a temporary detour. Welcome to the future of cognitive health.

For fifty years the story has been that the Moon assembled slowly out of a disc of debris. New simulations from Southwest Research Institute add one thing everybody left out — the strength of rock — and get an intact Moon in about five hours. Plus eight black holes that outgrew their galaxies, two massive stars that fell past each other and got caught, Dragonfly's Titan landing site gets a name, and today's daylight occultation of Jupiter.Links & sources Southwest Research Institute — SwRI-led modeling identifies new scenarios for Moon formation — https://www.swri.org/newsroom/press-releases/swri-led-modeling-identifies-new-scenarios-moon-formation Denton, Canup, Asphaug et al. — The Astrophysical Journal Letters (DOI) — https://doi.org/10.3847/2041-8213/ae91e9 Space.com — Earth's moon could have formed in just 5 hours after giant impact — https://www.space.com/astronomy/moon/earths-moon-could-have-formed-in-just-5-hours-after-giant-impact Buchner et al. — A large population of overmassive black hole quasars at z=0.3–0.8 revealed by eROSITA, A&A 713, A11 — https://www.aanda.org/articles/aa/full_html/2026/09/aa59356-26/aa59356-26.html Astronomy & Astrophysics — 2026 press releases — https://www.aanda.org/2026-press-releases Zhang, Garay et al. — An eccentric massive protobinary assembled via a core-merger parabolic encounter, Nature Astronomy — https://www.nature.com/natastron/articles?year=2026 Universidad de Chile coverage of the IRAS 07299-1651 result — https://www.radiofestival.cl/la-danza-nupcial-de-estrellas-masivas-astronomo-de-la-universidad-de-chile-participa-de-historico-hallazgo/ NASA / APL — Dragonfly Gets Wired Up While Titan Landing Area Is Named — https://science.nasa.gov/blogs/dragonfly/2026/09/02/nasas-dragonfly-gets-wired-up-while-titan-landing-area-is-named/ Sky & Telescope — Tuesday's daytime Jupiter occultation, a warm-up for the 'big one' — https://skyandtelescope.org/astronomy-news/tuesdays-daytime-jupiter-occultation-a-warm-up-for-the-big-one/ Universe Today — September's lunar occultations: circumstances and visibility — https://www.universetoday.com/articles/penultimate-lunar-occultations-inbound-for-jupiter-venus-and-more-in-september NASA — What's Up: September 2026 skywatching tips — https://science.nasa.gov/solar-system/skywatching/whats-up-september-2026-skywatching-tips-from-nasa/ EarthSky — Visible planets and night sky guide for September — https://earthsky.org/astronomy-essentials/visible-planets-tonight-mars-jupiter-venus-saturn-mercury/Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-latest-space-news--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.astronomydaily.io/nordvpn. You'll be glad you did!Get the best secure and private email on the planet. Stop your Government, google and who knows who else spying on every email you write. Do what we did and use ProtonMail. They beleive in privacy and there are no ads in their business model...yet they still provide a free forever service. Check them out and get out special deal at www.astronomydaily.io/protonmailBecome a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click HereThis episode includes AI-generated content.

If you prefer to watch the video you can find it at the bottom of this webpage. Episode Sponsors: Concealed Carry Gun Tools App: The #1 tool for concealed carriers on your phone. Check laws, maps, and stay informed with a great app on your phone. BarrelBlok: In those moments you need to be sure your gun is clear; BarrelBlok it. About This Episode: Today, Riley Bowman and Jacob Paulsen are bringing you our Legislative and Legal Updates episode — and August may have been the single biggest month for gun law in decades. Two federal courts struck down long-standing rules, the DOJ reversed a decades-old position on carrying in post offices, New Mexico’s waiting period finally died, and the FBI quietly released a crime report that nobody on the other side seems eager to talk about. California, meanwhile, just sent three more bills to the Governor’s desk. But the big one is the NFA. You’ve seen the headlines saying it’s dead. Riley read the actual court order, and it isn’t — not for most of you. He also thinks the Justice Department made a serious mistake in how it handled the win, and that’s the part almost nobody is talking about. Jacob pushes back. Tune in so you don’t miss! As always, any questions or suggestions for future episodes can be submitted to podcast@concealedcarry.com! News Stories Referenced In This Episode Silencer Shop Ruling: The NFA Is Not Dead Federal Judge Strikes Down NFA Registration for Suppressors and SBRs DOJ Says Lawful Gun Owners Can Carry in Post Offices Federal Judge Rules Biden-Era Ghost Gun Restrictions Unconstitutional District Court Enters Final Judgment Striking Down New Mexico’s Waiting Period Law in NRA Victory California Anti-Gun Bills Pass the Legislature, Now Heading to the Governor’s Desk SCOTUS Statutory Ruling Not the Final Word on Biden-Era Frame or Receiver Rule FBI Releases Final Crime Report for 2025 to the Dismay of Firearm Prohibitionists DOJ’s Post Office Directive Marks Another Second Amendment Milestone Federal Firearms Rights Restoration FBI Releases 2025 Reported Crimes in the Nation Statistics FBI’s Latest Report Leaves ‘More Guns, More Crime’ Hypothesis in Tatters Texas News Report — The Center Square Grassroots Judicial Report — August 26, 2026 Thanks for Listening! Thanks so much for joining us this week. Have some feedback you'd like to share? Leave a note in the comment section below. If you enjoyed the podcast the biggest compliment you could give us would be to subscribe to future episodes via a podcast app on your phone or via iTunes. You can find past podcast episodes by clicking here. Video Recording: Press PLAY on the video below to watch the video recording! {"@context":"https://schema.org","@type":"VideoObject","@id":"https://www.concealedcarry.com#/schema/video/4255667","name":"S14E6: Legislative Updates-The NFA Isn’t Dead, And Why That Should Bother You","description":"Concealed Carry Podcast brought to you by HK - "S14E6: Legislative Updates-The NFA Isn't Dead, And Why That Should Bother You" Episode Sponsors: -Concealed","thumbnailUrl":"https://i.ytimg.com/vi/RJWtrVw3MEo/maxresdefault_live.jpg","uploadDate":"2026-08-28T19:11:31-06:00","embedUrl":"https://www.concealedcarry.com/player-embed/id/4255667/?autoplay=0","duration":"PT01H15M03S","interactionStatistic":{"@type":"InteractionCounter","interactionType":{"@type":"http://schema.org/WatchAction"},"userInteractionCount":4}}

We investigate an unconvincing argument that the final secret focuses on Portugal from the third volume in The Whole Truth About Fatima.Please support the Our Lady of Fatima Podcast:http://buymeacoffee.com/TerenceMStantonLike and subscribe on YouTube:https://m.youtube.com/@OurLadyOfFatimaPodcastFollow us on X:@FatimaPodcastThank you!

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Modern companies, markets, and institutions routinely behave in ways that would be diagnosed as pathological in a person: emotional detachment, strategic deception, grandiosity, and the treatment of people, animals, and ecosystems as means to an end. Yet, most of the individuals who make up these organizations don't naturally hold these traits and behaviors themselves. So, why does exploitation keep winning at scale, even when most people are decent, cooperative, and want the same basic things?   In this episode, Nate is joined by Greg Elliott, a systems theorist and author of the Psychopathic Selection Hypothesis (PSH), to unpack why our institutions themselves have become so psychopathic, and how that affects the behavior of the average human. Drawing on evolutionary game theory, anthropology, and the neuroscience of psychopathy, Greg argues that cooperation is evolutionarily stable in small tribal systems, but that modern systems where anonymity and abstraction make exploitative, instrumental strategies more profitable. He walks through how this dynamic produces what he calls "entrapment games," in which pro-social people become behaviorally locked into relationships, jobs, and systems where leaving costs more than staying.  All of this builds toward the core of Greg's theory: winning, instrumental strategies get crystallized into the operating logic of institutions themselves and reproduced by anyone who plays the game, whether or not they are personally psychopathic. While Greg doesn't see any easy answers, he does offer a set of possible leverage points: shortening feedback loops, increasing transparency and accountability, and rebuilding smaller, reciprocal communities. If domination isn't an aberration but a predictable output of the game board we've built, what does that mean for how we try to fix it? Is it possible for an entire civilization to behave psychopathically even when the vast majority of the individual people inside it are empathetic and pro-social? And if the ultimate goal is to steer toward a more pro-social system, is there a way to 'win the game' and re-write the rules without also resorting to psychopathic strategies and behaviors? (Conversation recorded on August 13th, 2026)   About Greg Elliott: Greg is a Siemens solutions Consultant specializing in data science and AI, as well as the Co-Founder of Orbyfy. His research and writing of his book, Psychopathic Selection Hypothesis: From Natural Selection to Symbolic Selection, Scale, Abstraction, and Institutional Collapse, led him to found The Institute for Symbolic Selection, an interdisciplinary research program investigating how human-created symbolic systems shape behavior, institutions, and the long-term evolution of civilization.    New to game theory? Here's a short primer:  Game theory is the study of how people make decisions when the outcome depends on what everyone else decides too, often with the potential for mutual gain or mutual harm. Its most famous illustration is the Prisoner's Dilemma: two people, each individually better off betraying the other, who both end up worse off when they do.   For a deeper understanding, check out these links: - Game Theory video explainer: https://www.youtube.com/watch?v=2ecJ_fDpWTg  - Game Theory article explainer: https://www.econlib.org/library/Enc/GameTheory.html  - Prisoner's Dilemma video explainer: https://ed.ted.com/lessons/how-to-outsmart-the-prisoner-s-dilemma-lucas-husted    Show Notes and More   Watch this video episode on YouTube   Want to learn the broad overview of The Great Simplification in 30 minutes? Watch our Animated Movie.   ---   Support The Institute for the Study of Energy and Our Future   Join our Substack newsletter   Join our Hylo channel and connect with other listeners  

Hypothesis 15  

In this episode, we discuss Sadie's (as of yet unproven but highly promising) Hypothesis about the risk factors between growing up with religious trauma and experiencing domestic violence as an adult.Resources:“Experiencing Child Abuse Increases Risk for IPV in Adulthood” - Psychology Today https://www.psychologytoday.com/us/blog/invisible-bruises/202412/experiencing-child-abuse-increases-risk-for-ipv-in-adulthood?msockid=2ba568d81b3f696a252c7fd51a9768c8Study correlating religious abuse and domestic violence – https://vashtiinitiative.org/wp-content/uploads/2025/05/rts-connections-to-dv-and-sa-preliminary-res.pdf“A Commentary on Religion and Domestic Violence” by Rev. Dr. Marie M. Fortune with Salma Abugideiri and Rabbi Mark Dratch – https://evawintl.org/wp-content/uploads/A-Commentary-on-Religion-and-Domestic-Violence.pdfSubscribe to Leaving Eden Podcast on YouTube!https://www.youtube.com/channel/UCJ4q94gAnsoW2jME4SvVrrQJoin our Patreon for extended, uncensored, and ad-free versions of most of our episodes, as well as other patron perks and bonus content!https://www.patreon.com/LeavingEdenPodcastJoin our Facebook group to join in the discussion with other fans!https://www.facebook.com/groups/edenexodusJoin our subreddit! Reddit.com/r/EdenExodusBluesky:@leavingedenpodcast.bsky.social@hellyeahsadie.bsky.social@gavihacohen.bsky.socialInstagram:https://www.instagram.com/leavingedenpodcast/https://www.instagram.com/sadiecarpentermusic/https://www.instagram.com/gavrielhacohen/ Hosted on Acast. See acast.com/privacy for more information.

Hypothesis 15  

Todd reviews some interesting training camp notes that could impact the fantasy value of DeVonta Smith and TreVeyon Henderson in 2026. The Todd Wright Fantasy Football Podcast is presented by Hooters! Click above to listen or download, or at Apple […] The post The Dreaded Alvin Harper Hypothesis appeared first on JoeBucsFan.com.

The difference between being healthy or not healthy mostly comes down to the simple things within your control like eating nutrient-rich foods, incorporating movement into your daily routine and following a stable sleep schedule.Like Paul, BIOptimizers co-founders, Matt Gallant and Wade Lightheart, constantly test, test and test their bodies, beliefs and products to ensure those simple things are always protecting and enhancing better health.Building on that theme of experimenting, Matt talks about the 80,000+ experiments he's done on BIOptimizers products over the years and Wade shares his bucket theory of nutrition that will make your health more bulletproof this week on Spirit Gym.Besides the many great BIOptimizers products Wade and Matt have developed, you'll want to check out the BIOptimizers Nutrition Coach Program. Look for Matt and Wade on social media via Facebook, Instagram, TikTok and YouTube. Listen to the BIOptimizers Awesome Health Podcast hosted by Wade on Apple Podcasts.Timestamps2:19 Is maltodextrin in your electrolyte drink?6:08 BiOptimizers' bio-lab recently topped the 80,000 mark in experiments.10:17 Wade's concussion theory.24.28 “Matt loves running experiments on everything.”32:42 Do you have a zinc deficiency?38:32 Can you really feel the truth?51:30 How to make your health more bulletproof.1:00:37 Wade's bucket theory of nutrition.1:08:55 Feeling the sensation of a weightlifter's/athlete's heart.1:16:38 Understanding cofactors.1:22:53 “One of the hardest things [for humans] to absorb is fat soluble molecules.”1:33:21 Protecting your microbiome.1:45:44 Wade's small confession.1:53:30 The power of the placebo and the biology of belief.2:02:00 The benefits of experiential reality.2:17:06 Substitute the word belief for hypothesis and your life will change.2:23:00 “Children are the ultimate health hack.”ResourcesThe Ultimate Nutrition Bible by Matt Gallant and Wade LightheartOrthomolecular Psychiatry: Treatment Of Schizophrenia by Dr. David Hawkins and Dr. Linus PaulingBioaccessibility, bioavailability and metabolism of functional foods, Handbook of Functional FoodsPaul's podcast conversation with Jason ChristoffHildegard von Bingen's Physica by Saint Hildegard of Bingen and Priscilla ThroopThe Fat of the Land by Vilhjalmur StefanssonYour Body's Many Cries for Water by Fereydoon BatmanghelidjThe Body Electric: Electromagnetism and the Foundation of Life by Robert Becker and Gary SeldenTuning in to Nature by Philip CallahanBiochemical Individuality by Roger WilliamsFind more resources for this episode on our website.Music Credit: Meet Your Heroes (444Hz), Composed, mixed, mastered and produced by Michael RB Schwartz of Brave Bear MusicThanks to our awesome sponsors:PaleovalleyBIOptimizers US and BIOptimizers UK PAUL15Organifi CHEK20Spirit GymCHEK InstituteWe may earn commissions from qualifying purchases using affiliate links.

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If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects.  In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge.  So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below.  Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Substackhttps://substack.com/@theoccultrejects?r=7auau0&utm_campaign=profile&utm_medium=profile-pageCash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsPrimary SourcesPrimary SourcesAeschylus. Eumenides.Cicero. On Divination.Herodotus. The Histories.Homeric Hymn to Apollo.Pausanias. Description of Greece. Book 10.Pindar. Pythian Odes.Plutarch. Life of Lycurgus.Plutarch. “On the E at Delphi.” In Moralia.Plutarch. “The Obsolescence of Oracles.” In Moralia.Plutarch. “The Oracles at Delphi No Longer Given in Verse.” In Moralia.Strabo. Geography.Official and Reference SourcesArchaeological Site of Delphi, Hellenic Ministry of Culture. “Excavations.”Archaeological Site of Delphi, Hellenic Ministry of Culture. “History of Delphi.”Archaeological Site of Delphi, Hellenic Ministry of Culture. “Mythological Versions of the Foundation of the Oracle.”Archaeological Site of Delphi, Hellenic Ministry of Culture. “The Sphinx of the Naxians.”Archaeological Site of Delphi, Hellenic Ministry of Culture. “The Temple of Apollo.”Archaeological Site of Delphi, Hellenic Ministry of Culture. “The Treasury of the Siphnians.”Encyclopaedia Britannica. “Delphi.”Encyclopaedia Britannica. “Delphic Oracle.”Encyclopaedia Britannica. “Hieromnemon.”Encyclopaedia Britannica. “Python.”Encyclopaedia Britannica. “Pythian Games.”UNESCO World Heritage Centre. “Archaeological Site of Delphi.”Modern ScholarshipChappell, Mike. “Delphi and the Homeric Hymn to Apollo.” The Classical Quarterly 56, no. 2 (2006).de Boer, Jelle Z., John R. Hale, and Henry A. Spiller. “The Delphic Oracle: A Multidisciplinary Defense of the Gaseous Vent Theory.” Clinical Toxicology 40, no. 2 (2002).Etiope, Giuseppe, et al. “The Geological Links of the Ancient Delphic Oracle.”Fontenrose, Joseph. The Delphic Oracle: Its Responses and Operations, with a Catalogue of Responses. Berkeley: University of California Press, 1978.Forrest, W. G. “The First Sacred War.” Bulletin de Correspondance Hellénique 80 (1956).Fragkaki, Maria. “The Great Rhetra.” Rosetta 17 (2015).McInerney, Jeremy. “Parnassus, Delphi, and the Thyiades.” Greek, Roman, and Byzantine Studies 38, no. 3 (1997).Piccardi, Luigi. “Active Faulting at Delphi, Greece: Seismotectonic Remarks and a Hypothesis for the Geological Environment of a Myth.” Geology 28, no. 7 (2000).Scott, Michael. Delphi: A History of the Center of the Ancient World. Princeton: Princeton University Press, 2014.Strolonga, Polyxeni. “The Foundation of the Oracle at Delphi in the Homeric Hymn to Apollo.” Greek, Roman, and Byzantine Studies 51 (2011).Music, Inscriptions, and ArchaeologyArchaeological Museum of Delphi. Museum collections and interpretive materials.The Delphic Hymns to Apollo.École française d'Athènes. Fouilles de Delphes.Also want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. 

Hypothesis 13  

In 1950, physicist Enrico Fermi asked a very simple yet important question: If the universe has intelligent civilizations, as so many people believe, where are they? This became known as the Fermi Paradox, and it has been one of the foremost philosophical and scientific questions of our age.  One of the most straightforward answers to the Fermi Paradox is also one that many people simply don't want to believe. Learn more about the Rare Earth Hypothesis and how we might actually be alone on this episode of Everything Everywhere Daily. Shop the store at Shop.Everything-Everywhere.com Sponsors Hexclad Get 10% off your order at hexclad.com/DAILY Mint Mobile Save 50% on Unlimited premium wireless plans starting at $15/month at MintMobile.com/EED Quince Go to quince.com/daily for 365-day returns, plus free shipping on your order! DripDrop Go to dripdrop.com and use promo code EVERYTHING for 20% off your first order! Subscribe to the podcast!  https://everything-everywhere.com/everything-everywhere-daily-podcast/ -------------------------------- Executive Producer: Charles Daniel Associate Producers: Austin Oetken & Cameron Kieffer   Become a supporter on Patreon: https://www.patreon.com/everythingeverywhere Discord Server: https://discord.gg/Ds7Rx7jvPJ Instagram: https://www.instagram.com/everythingeverywhere/ Facebook Group: https://www.facebook.com/groups/everythingeverywheredaily Twitter: https://twitter.com/everywheretrip Website: https://everything-everywhere.com/  Disce aliquid novi cotidie Learn more about your ad choices. Visit megaphone.fm/adchoices

If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects.  In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge.  So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below.  Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Substackhttps://substack.com/@theoccultrejects?r=7auau0&utm_campaign=profile&utm_medium=profile-pageCash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsFull Episode BibliographyPrimary SourcesAeschylus. Eumenides. Used for the ancient tradition of succession at Delphi and the mythic movement from older powers to Apollo.Cicero. On Divination. Used for ancient discussion of divination and the tradition of Delphic inspiration connected with breath or exhalation.Herodotus. The Histories. Used for Croesus, the danger of ambiguous prophecy, the Athenian “wooden wall” oracle, Themistocles' interpretation, and Delphi's role in war and public decision-making.Homeric Hymn to Apollo. Used for Apollo's Delphic foundation myth, the serpent, the movement from sacred landscape to Apollonian institution, and the Cretan priests connected with Apollo's dolphin form.Pausanias. Description of Greece, Book 10. Used for later ancient traditions concerning Delphi, foundation myths, Gaia, Themis, Python, Apollo, sacred monuments, and the Delphic landscape.Pindar. Pythian Odes. Used for the Pythian Games, victory poetry, Apollo, prestige, and the transformation of athletic victory into sacred memory.Plutarch. Life of Lycurgus. Used for Lycurgus, the Great Rhetra, and the tradition of Spartan law receiving Delphic sanction.Plutarch. Moralia: “On the E at Delphi.” Used for the mysterious letter E at Apollo's temple and ancient philosophical interpretations of its meaning.Plutarch. Moralia: “The Oracles at Delphi No Longer Given in Verse.” Used for Delphic verse, the change in oracular style, and ancient reflection on why the Pythia no longer gave responses in meter.Plutarch. Moralia: “The Obsolescence of Oracles.” Used for Delphi in the Roman period, the decline of oracular centers, Plutarch's reflections on divine inspiration, and the tradition that Delphi once had multiple priestesses.Strabo. Geography. Used for ancient geographical description of Delphi and the tradition of the oracle's inspiration being connected with a breath or vapor rising from below.Official and Reference SourcesArchaeological Site of Delphi / Hellenic Ministry of Culture. “History of Delphi.” Used for Delphi's geography, Mycenaean background, Apollo's cult, Python, Cretan priests, the Amphictyony, sacred administration, Sacred Wars, Roman history, decline, and excavation.Archaeological Site of Delphi / Hellenic Ministry of Culture. “Mythological Versions of the Foundation of the Oracle.” Used for Gaia, Themis, Phoebe, Apollo, Python, Poseidon, the tripod, Athena Pronaia, the Thriae, and the dolphin/Cretan priest tradition.Archaeological Site of Delphi / Hellenic Ministry of Culture. “The Temple of Apollo.” Used for the sacred center of the sanctuary, the adyton, the temple's rebuilding history, and the architectural setting of the oracle.Archaeological Site of Delphi / Hellenic Ministry of Culture. “The Sphinx of the Naxians.” Used for the Naxian dedication, apotropaic symbolism, civic prestige, and the monument's role in the Sacred Way.Archaeological Site of Delphi / Hellenic Ministry of Culture. “The Treasury of the Siphnians.” Used for the Siphnian Treasury, its sculptural program, caryatids, wealth, painted decoration, and sacred display.Archaeological Site of Delphi / Hellenic Ministry of Culture. “Excavations.” Used for the Great Excavation, the village of Kastri, French archaeological work, and the modern recovery of Delphi.Encyclopaedia Britannica. “Delphic Oracle.” Used for the Pythia, Apollo's oracle, Delphi's high prestige, and the use of Apollo's sanction by lawmakers, colonists, and political leaders.Encyclopaedia Britannica. “Delphi.” Used for the general history and significance of Delphi as a sanctuary, oracle, and pan-Hellenic religious center.Encyclopaedia Britannica. “Python.” Used for Python as the serpent or dragon killed by Apollo at Delphi.Encyclopaedia Britannica. “Pythian Games.” Used for the games at Delphi, their musical and athletic character, their relationship to Apollo, and the laurel wreath.Encyclopaedia Britannica. “Hieromnemon.” Used for the Amphictyony, pylagorai, hieromnemones, treasury supervision, and administration of sacred affairs.UNESCO World Heritage Centre. “Archaeological Site of Delphi.” Used for Delphi's world heritage description, pan-Hellenic importance, sacred landscape, and historical significance.Modern ScholarshipChappell, Mike. “Delphi and the Homeric Hymn to Apollo.” The Classical Quarterly 56, no. 2, 2006. Used for the Homeric Hymn's Delphic foundation narrative and Apollo's Pythian identity.Fontenrose, Joseph. The Delphic Oracle: Its Responses and Operations with a Catalogue of Responses. Berkeley: University of California Press, 1978. Used as a major scholarly backbone for Delphic responses, authenticity problems, categories of consultation, and the operation of the oracle.Forrest, W. G. “The First Sacred War.” Bulletin de Correspondance Hellénique 80, 1956. Used for the First Sacred War, Krisa/Crisa, sacred access, and the political framing of Delphi's early pan-Hellenic importance.Fragkaki, Maria. “The Great Rhetra.” Rosetta 17, 2015. Used for the Great Rhetra as a Delphic oracle and the divine validation of Spartan political order.McInerney, Jeremy. “Parnassus, Delphi, and the Thyiades.” Greek, Roman, and Byzantine Studies 38, no. 3, 1997. Used for Dionysus, the Thyiades, Parnassus, mountain ecstasy, and the fact that Delphi's sacred landscape was not purely Apollonian.Piccardi, Luigi. “Active Faulting at Delphi, Greece: Seismotectonic Remarks and a Hypothesis for the Geological Environment of a Myth.” Geology 28, no. 7, 2000. Used for Delphi's faulted landscape and the modern geological debate around the oracle.de Boer, Jelle Z., John R. Hale, and Henry A. Spiller. “The Delphic Oracle: A Multidisciplinary Defense of the Gaseous Vent Theory.” Clinical Toxicology 40, no. 2, 2002. Used for the modern argument that gases, possibly including ethylene, may have contributed to the Pythia's altered state.Etiope, Giuseppe, et al. “The Geological Links of the Ancient Delphic Oracle.” Used for critique and reassessment of the geological and gaseous explanations of Delphic inspiration.Scott, Michael. Delphi: A History of the Center of the Ancient World. Princeton: Princeton University Press, 2014. Used for the broader historical arc of Delphi as sacred center, political institution, cultural symbol, and archaeological site.Strolonga, Polyxeni. “The Foundation of the Oracle at Delphi in the Homeric Hymn to Apollo.” Greek, Roman, and Byzantine Studies 51, 2011. Used for Apollo's foundation myth and the literary shaping of Delphi's origin story.Music, Inscriptions, and ArchaeologyFouilles de Delphes. École française d'Athènes. Used for the archaeological publication tradition connected with Delphi's excavation, architecture, inscriptions, sculpture, and sanctuary remains.The Delphic Hymns to Apollo. Used for Apollo's musical cult, sacred song, and the role of hymn, inscription, and performance at Delphi.Archaeological Museum of Delphi materials. Used for the Charioteer, Antinous, Kleobis and Biton, the Sphinx of the Naxians, the Siphnian Treasury, and other major finds from the sanctuary.Also want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. 

When software can be built and copied faster than ever, what still makes a consumer product stand out? Episode #4 of Consumer Tech Napkin, produced in partnership with True, explores how strong teams create an edge through user love, distribution, experimentation, learning loops and human judgement.Host Andreas Munk Holm is joined by Neil Tanna, Co-Founder and CEO of Howbout, Graham Paterson, Co-Founder and CEO of Jitty and an angel investor in Howbout, and Mike Martin of True, a consumer and retail-focused investor and an investor in Jitty.Howbout is the shared calendar app for keeping up with friends and has grown to more than seven million users across 125 countries. Jitty is the search engine for finding your next home.They discuss why features rarely create lasting defensibility, what separates a genuine experiment from simply shipping and hoping, how teams balance data with product taste and how AI is changing the speed of product development.HighlightsBuilding great products when features are easy to copyDistribution, user love and learning loopsIdeas versus executionWhat makes a genuine product experimentIncremental improvements versus bigger betsHow Howbout tests higher-risk changesWhere human judgement remains essentialTimestamps(01:00) Building great products when software is easy to copy(04:00) Does a unique founding insight still matter?(08:00) Ideas versus execution(11:00) The rising bar for consumer startups(13:00) Distribution as a moat(17:00) Why learning loops create an advantage(19:00) What makes an experiment?(20:00) Hypothesis-led product development(22:00) Product bets and building for remarkability(25:00) Where to test risky ideas(28:00) How Howbout runs experiments at scale(32:00) Lessons from Deliveroo's logistics experiments(34:00) How AI accelerates shipping and analysis(37:00) Can AI run experiments autonomously?(39:00) Why human taste still matters(43:00) How audience size compounds learning(45:00) Closing thoughtsSubscribe to EUVC, the home of European tech, for more insights.

Hypothesis 13  

Alan Mikhail discusses his book Newcomers, focusing on Anthony Jansen, known as "the Turk." Mikhail uses historical records to debunk the 150-year-old hypothesis that Anthony was the son of a Dutch pirate who converted to Islam, instead tracing his origins back to 17th-century Spain. (9)NEW AMSTERDAM

The Outer Realm welcomes the return of Friend and fellow UPRN Host of The Angel Rock Lorilei Potvin Date: July 15th, 2026 EP: 745 DISCUSSION: Jon us for another segment of the Celebrity Mystery Series. Picking up somewhat from where we left off in our last show, discussing Clones, we will explore the possibility of Time Travel as it seems to surface as a conspiratorial hypothesis within the mysterious Celebrity World. Please join us in chat to participate in this open discussion. Contact for the show - theouterrealmcontact@gmail.com https://linktr.ee/michelledesrochers_ Please support The show by Liking, Subscribing, Sharing and Commenting. Thank you all !!! About Lorilei: Lorilei Potvin a Canadian Clairvoyant Medium, Crystal Reiki Master/Energy Healer, Akashic Records Practitioner, Medical Intuitive, Spiritual Teacher/Mentor, Internet Radio Host/Podcaster, Humanitarian Activist & Registered Nurse. She is also very knowledgeable about The Paranormal, having lived in an extremely haunted Home for 11 + years. Lorilei has shared her story on The Travel Channel's “Paranormal Survivor”, in Season 4, Episode 9, called “Demonic Hauntings”(here's a link to the Episode: https://youtu.be/OkoOcAL-Feg Lorilei's 2 shows are “The Angel Rock” on Mondays from 6pm-8pm EST & she co-hosts “Beneath The Hollow Moon " with Kerrilynn Shellhorn on Thursday Nights , 7pm-9pm EST, with David Hanzel; both shows are on United Public Radio Network or UPRN, out of New Orleans, Louisiana. Both shows can be seen LIVE-STREAMED from Her YouTube channel below, as well as Our Network YouTube channels, Facebook Page & anywhere podcasts &/or Talk Radio is carried. Find Her Here: https://www.facebook.com/TheAngelRock My YouTube channel: https://www.YouTube.com/c/TheAngelRockWithLorileiPotvin If you enjoy the content on the channel, please support us by subscribing: Thank you All !!! A formal disclosure: The opinions and information presented or expressed by guests on The Outer Realm Radio and Beyond The Outer Realm are not necessarily those of the TOR, BTOR Host, Sponsors, or the United Public Radio Network and it's producers. For Legal Purposes, all content must be listed and deemed "For Entertainment Purposes" We are always be respectful and courteous to all involved. Thank you, we appreciate you all United Public Radio & UFO Paranormal Radio www.uprntalkradio.com

 Happy Episode 100!Johnny will be returning to the stage in a play in Chicago, Jim is still on Broadway in Titanique (and we chat about the state of current Broadway shows)Our episode discussion includes the Pilot parallels, how well Leonard knows everyone in the group, the Leonard/Penny of it all (of course), and celebrating 100 episodes without going overboard.The play mentioned by Nicole is "Sure Thing." And here is information on the Seward Shame Pole.Download hereRunning time: 1:18:49, 56.9 MB

An overview of the theory that UFOs are time travelers from the future, along with a Christian approach to the nature of time and the possibility of time travel. Colin's Book: “Ministration of, and Communion with Angels “ HERE Discount Code is CULTISH10 “Ministration of, and Communion with Angels presents a robust doctrine of angels and explores their ministry in the lives of God's people. With sobriety and spiritual seriousness, Ambrose calls believers to recover a full-orbed supernatural worldview—one in which God's holy angels guard, guide, and minister according to His sovereign will.” SHOP OUR MERCH: HERE Please consider subscribing to our YouTube Channel: CultishTV.com Cultish is a 100% crowdfunded ministry.  Be Part of the Mission to Change Lives: HERE SHOP OUR MERCH: HERE

303# Where Are the Little Green Men? | Terry Adair's Energy HypothesisFor decades, scientists have wrestled with the Fermi Paradox: if the universe is so vast and potentially full of life, why haven't we found any evidence of advanced civilisations?In this episode of Never A Straight Answer, we're joined by author Terry Adair to explore his thought-provoking idea known as The Adair Hypothesis. Rather than focusing on intelligence or biology, Terry argues that the real barrier preventing civilisations from reaching the stars is something much more fundamental—energy.Together we explore the Great Filter, the future of humanity, SETI, the challenges every technological civilisation must overcome, and whether our own species is approaching—or struggling through—the same bottleneck that may have silenced countless others across the cosmos.Whether you're fascinated by UFOs, astronomy, physics, or simply love asking the biggest questions imaginable, this is a conversation that will leave you looking at the universe in a completely different way.Find Terry Adair's book Where Are the Little Green Men? The Adair Hypothesis here:

June was a long month, and Jonah Goldberg is feeling entitled to a little bit of self-indulgence. Instead of turning to the bottle, however, he has opted for a rollicking, frolicsome ramble through the deep history of conspiracy theory. Jonah is joined by Andrew McKenzie-McHarg, author of the definitive volume on the topic, to discuss conspiracy theory (singular), etymology, secularization, 19th-century social science, the paranoid style, The Protocols of the Elders of Zion, Argentina, magic and science, antisemitism, apocalyptic thinking, Karl Popper, Richard Hofstadter, Karl Marx, World War I, Donald Trump, social media, institutions, and Catholicism. Show Notes: —Andrew McKenzie-McHarg - The Hidden History of Conspiracy Theory —Jesse Walker - The United States of Paranoia: A Conspiracy Theory —Richard Hofstadter - “The Paranoid Style in American Politics” —Jesse Walker review of The Hidden History of Conspiracy Theory in Reason The Remnant is a production of ⁠The Dispatch⁠, a digital media company covering politics, policy, and culture from a nonpartisan perspective. To access all of The Dispatch's offerings—including the Saturday Ruminant, audio versions of all our articles and newsletters, and Jonah's twice-weekly G-File—⁠click here⁠. Instructions on how to set up your members-only feed can be found here, and if you'd like to remove all ads from your podcast experience, consider becoming a premium Dispatch member ⁠by clicking here⁠. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hosts: Ed Jones (Owner – Nutrition World) & Clint Powell A variety of topics all related to living a healthy life Presented by: Nutrition World www.nutritionw.com Broadcasting from the Nooga Dentistry Studio www.noogadentistry.com Production of: Whitfield Media Group www.vitalhealthradio.com Title: Breakthrough Treatments for C Diff with Guest Dr. Oscar, Kiwi for Bowel Regularity with Julia from Enzymedica [0:00:00] Opening, Banter, and Announcements Ed plugs an upcoming podcast episode on heartburn with Julia from Enzymedica, explaining simple steps to get off PPIs (proton pump inhibitors) safely. MMA fighter sponsor shout‑out Discussion of Chance, an 8–0 MMA fighter who works at Nutrition World's warehouse. Upcoming fight at Camp Jordan in July; Nutrition World is a sponsor. Ed describes Tallow House in Cleveland: Burgers cooked in tallow Sourdough buns, high-quality ingredients Comparison to seed oils, stating tallow is preferable, though any fat can be overdone. Setup for today's show / guests Dr. Oscar – discussing a “revolutionary” next‑generation probiotic based on a super donor / fecal transplant science. Julia from Enzymedica – discussing constipation and digestive enzymes. [0:08:56] Gut Microbiome & Origin of the MET Probiotic Ed reiterates the show's philosophy: better aging means adding strength, clarity, mobility, and energy to existing years. Emphasizes his longstanding passion for the gut microbiome and how cluttered/confusing that field is. Ed welcomes Dr. Oscar and frames the topic as a truly unique/probably revolutionary probiotic advance. Personal story: Ed's father died from C. diff about 20 years ago. C. diff often triggered by antibiotics, then treated with more antibiotics → vicious cycle. Ed wanted to give probiotics/Saccharomyces boulardii; doctor was lukewarm but allowed it. How the product started (C. diff & FMT) – Dr. Oscar Traditional fecal microbiota transplants (FMT): Helpful for C. diff, but risky for immunocompromised patients. Concerns: pathogens, genetic material, and “yuckiness.” Microbial Ecosystem Therapeutics (MET) A company developed an alternative: MET, using a single “super donor”. Process: Select a rigorously screened donor with a healthy microbiome, no gut issues. Extract unique anaerobic bacteria. Use lyophilization (freeze-drying) to remove the fecal material and problematic components, leaving a purified community of bacteria. Result: a blister‑pack capsule containing live anaerobic strains that can engraft in the gut. C. diff trials and efficacy Comparative trials (MET-1 / MET-2) vs. fecal transplants for C. diff: MET formulations performed as well or better than FMT in some outcomes. One MET‑based product has already been used specifically for C. diff. Transition to functional / preventive use The MET company partnered with Designs for Health and Guelph University (Ontario). After years of research and clinical work, they created a five‑strain formulation used in the Designs for Health product. Claim: these five strains regulate roughly 85% of metabolic and immune functions influenced by gut bacteria. [0:14:47] How this Probiotic Differs from Traditional Probiotics Ed underscores: Thousands screened to identify an optimal super donor with best diversity. Human‑sourced strains → high compatibility with human physiology. Wants clarification on aerobic vs. anaerobic differences and why they matter. Traditional probiotics vs MET strains – Dr. Oscar Traditional probiotics: Often from exogenous sources (fermented dairy, industrial fermentation, etc.). Usually Lactobacillus, Bifidobacterium etc. They are generally transient: Work while you take them. Poor ability to engraft and persist once discontinued because they're not native to the host. Still useful (like eating salad: benefits only while you keep consuming them). Human‑derived MET strains: Sourced from a human donor, recognized by the body as “self‑like.” Have co‑evolved with humans over long timeframes. Function as an “accessory organ system”: E.g., certain strains stimulate the production of new cells. Specific strain examples Akkermansia: Consumes mucin in the gut lining. Produces metabolites that activate stem cells and progenitor cells, leading to new cell formation in the gut. Other strains have specialized roles: Ferment food. Create an anaerobic environment. Modulate immune responses. Oxygen & anaerobes, “crowding out” pathogens Healthy human colon = low‑oxygen (anaerobic) environment. Certain beneficial strains (e.g., Roseburia) help remove oxygen: They create conditions where anaerobic commensals thrive. Pathogens and opportunistic bacteria that prefer oxygen are crowded out, not killed with antibiotics. Clinical observations: Pre‑ and post‑testing show reductions in overgrowth bacteria when taking this formulation. This suggests a “crowding out” approach vs. broad‑spectrum microbial killing. Terrain theory & engraftment duration Ed references terrain theory (Antoine Béchamp): improve the internal environment to resist disease. Engraftment data: Early engraftment seen in ~2 weeks. MET C. diff studies showed strains persisting up to 6 months. Key dependency: diet and “fertilizing” the microbiome. Good fiber, colorful plant foods, polyphenols → support long‑term survival. Threats: alcohol, glyphosate, long‑term antibiotics, stomach acid meds, narrow macro diets (strict keto, carnivore, low‑FODMAP) without adequate diversity. Solutions for narrow diets: add prebiotic fibers, greens/reds powders. Dosage & synergistic use with other probiotics Ed confirms he's taking one capsule per day of the Designs for Health product labeled “Next Generation Multi‑Strain Probiotic” and tolerating it well. Dr. Oscar: One cap is enough Emphasis on quality of the seed, not quantity (CFU count). High‑quality engrafting strains self‑propagate as long as diet supports them. Synergy with other probiotics: Example: Lactobacillus produces lactate, which serves as a food source for some MET strains. Hypothesis: traditional probiotics may have better persistence and function when the MET strains are present. Ed notes: Very high‑strain blends (20+ strains) may have unknown “infighting.” In contrast, a single donor community has already proven internal compatibility. Where to learn more Designs for Health website: designsforhealth.com Search “Complete Commensal” for patient education materials. Note: two of the strains have never before been available in commercial probiotics due to encapsulation challenges with strict anaerobes; newer technology solved this. [0:33:14] Constipation, Enzymes, Kiwi Regularity (with Julia from Enzymedica) Introducing Julia with Enzymedica Julia is a long‑time educator (20+ years) in the natural health industry. Ed compares clinical experience in natural health to a physician needing years of patient contact beyond textbooks. Julia: First-line advice – don't rely on stimulant laxatives Avoid over‑the‑counter stimulant laxatives except in rare, urgent situations. Chronic use irritates the bowel and makes it dependent, reducing natural motility. Foundational step: chew your food & nervous system calm Proper chewing: Activates salivary amylase and lipase (carb and fat‑digesting enzymes). Signals stomach acid secretion and subsequent digestive steps. Ed notes: Most people eat while on their phones, in a rushed state. He tries to pause for ~1 minute before eating to reset. Good digestion starts even with thought and sight of food. Why constipation happens & normal frequency Normal bowel frequency: At least once daily, ideally 2–3 times/day. Some people report going only once a week, which is problematic. If food is not broken down properly: The body delays gastric emptying and slows peristalsis. Leads to constipation, gas, and bloating. Digestive enzymes: Help break food down. Improve signal timing for stomach emptying and intestinal motility. Provide relatively rapid symptom relief (gas, bloating, heavy stomach). Symptoms of delayed gastric emptying Can manifest as: Heaviness (“rocks in my stomach”). Minimal or absent bowel movements. Bloating, gas, occasional heartburn, and nausea. GLP‑1 drugs (e.g., Ozempic and similar): Work partly by slowing gastric emptying. Can exacerbate pre‑existing motility issues. Digestive enzymes are compatible and can help. Enzyme basics & age Humans make tens of thousands of enzymes, but production declines with age. This explains why people often say: “I used to be able to eat X, and now I can't.” Gut–brain link & psychological burden Many neurotransmitters (or their precursors) are made/processed in the gut: Serotonin, dopamine, norepinephrine, etc. Poor gut function → can influence mood, sleep, appetite, social drive. Constipation/diarrhea leads to stress, anxiety, fear of leaving home (e.g., unpredictable loose stools). Kiwi Regularity: a non‑stimulant “regulating” approach Product: Enzymedica Kiwi Regularity (chewable). Based on a concentrated kiwi extract, not a harsh laxative. Works in both directions: Helps people who can't go (constipation). Helps bind loose stools (diarrhea/urgency). Gently supports motility and microbiome over time. Miralax concerns Ed and Julia criticize chronic use of Miralax: Widely prescribed, even for children. Kiwi Regularity: Gentle, non‑addictive, appropriate for: Children. Pregnant women (though labeling can't state it due to regulations). Works long‑term and supports microbiome. Shown in 4‑week studies to: Increase commensal Bifidobacteria. Support Akkermansia and butyrate production. Butyrate nourishes colon cells and supports gut barrier. [0:43:01] Practical Enzyme Use, Histamine, and Product Recommendations Industrial vs human‑oriented enzymes Many enzymes on the market were originally developed for industrial uses. Enzymedica (since 1998) focused specifically on human digestive enzymes and research. Emergency backup vs daily habits Ed shares a travel anecdote: Severe constipation scenario solved with a Fleet enema while out of town. Enemas are non‑addictive, suitable for rare emergencies. Emphasizes hydration and magnesium: Magnesium (especially certain forms) helps pull water into the bowel. Regular use of magnesium oxide solely as a laxative is not ideal; better to use more balanced forms (e.g., magnesium glycinate). Most people over ~30 benefit from enzymes Declining enzyme production with age + modern diet → strong case for broad digestive enzyme support. Histamine & DAO enzymes Enzyme DAO (diamine oxidase) can help break down histamine from food. It's typically porcine‑sourced. Crucial caveat: Must pair with a low‑histamine diet; enzymes alone won't fully overcome high‑histamine intake. Gluten‑digesting enzymes limits Gluten enzyme products can help with cross‑contamination or minor slip‑ups. They are not a license to eat full gluten-rich meals (like a whole pizza) with impunity. Which Enzymedica product for the “average American diet”? For “standard” American eating patterns (larger, richer, mixed meals): Digest Gold: Enzymedica's most potent formula. Suited for heavy or complex meals, people early in their digestive-health journey. For somewhat cleaner / smaller meals: Digest Complete: Slightly smaller capsule, still potent. Good for those who have already improved diet somewhat. Enzymedica's research shows digestive enzymes also support microbiome health, not just symptom relief. In the broader health context, Both Julia and Ed highlight: Modern environmental and lifestyle burdens (glyphosate, EMFs, etc.). Need for foundational supports: enzymes, probiotics, microbiome‑friendly diet. Where to learn more Website: enzymedica.com Contains educational articles, research summaries, and product info. Ed notes Enzymedica has extensively trained Nutrition World staff on enzymes, heartburn, slow/fast transit, etc. [0:55:36] Final Segment Ed references a study: A single course of antibiotics can alter gut microbiome for years, affecting digestion, immunity, and metabolic health. Most recover within first two years post‑antibiotics, but not fully without support. Reaffirms importance of probiotics and enzymes on the “first page” of gut health tools.  Balanced view on medicine Acknowledge a time and place for antibiotics and conventional care (e.g., pneumonia, UTIs). Stress avoiding reflexive decisions based on fear; consider pros/cons, then act. The post Radio Show / Podcast – June 28, 2026 first appeared on Vital Health Radio.

It is Randall's contention that humanity faces two existential threats: man-made geopolitical conflict and natural cosmic catastrophes. He suggests that the global arms race is a manufactured distraction that prevents nations from addressing the genuine danger of repetitive Earth-cosmos interactions. In this compelling episode of Squaring The Circle, Randall advocates for a profound shift in consciousness to move past modern political rivalries and instead foster international cooperation.   By redirecting resources towards a new space economy, he believes society can build the infrastructure necessary to protect against extraterrestrial threats. Ultimately, Randall is calling for a collective awakening of the human spirit before a catastrophic event forces itself upon the world. HELP SAVE THE BEES! TO PARTICIPATE, BENEFIT & SUPPORT: Use code: RANDALL for 20% OFF at https://4rbees.com

Yes, you are in!  Where did God come from?  An excellent Deeper question for your next date night or small group ice breaker or family time.  Inspired by a comment i made on the previous Algorithms episode.  We'll tackle it.  Here you go...Thank you sincerely for clicking in.  When worthy, thank you for sharing.  Avid listener, you know my odd fixation to share Rom 3:23.  For we are all flawed.  I am a flawed dude.  Not everything that comes out of my mouth is correct.  I will make mistakes.  If you believe in God and Jesus Christ and the Holy Spirit, then let the Word be your ultimate guide.  Use that Owner's Manual for Life to quality control check any book or sermon or episode you hear or watch.  Of course, make sure to take the whole Bible in consideration.  Isolating on just one verse not in context can be equally dangerous.  So considering all that.  Where did God come from?  In the previous episode you hear me hypothesize about what preceded us.  We spoke about Algorithms and that AI can finally get through are thick skeptical heads that there can be and is something much more smarter and powerful than us.  Up til the latest tech, atheists that they were the smartest.  I hypothesized what if there was a previous civilization.  Hypothesis is the key word.  To be clearly, it was merely an attempt to help that skeptic find that mustard seed of faith.  That existed before you, me, and humanity alone.  To be clear, I do believe in the beginning, God created the heavens and the earth.  That is my Faith.  Something absolutely started this.  That a code (your DNA code and mine) cannot exist without a coder.  So where did God come from?  Where did our coder come from?  How did our coder become the coder?  Short answer, I don't know.  What I do know is something can't come from nothing.  Even an atheist scientist has to grapple with that statement.  As for believers, where in the Bible does it explain where God comes from?  If you see something that I don't, please let us know at the Contact Us page at fridudes.com.  What I do know is that we have an explanation of a Creator.  An all knowing Creator that designed and created us.  And as I just confess, that sounds a bit crazy until GenAI came along.  Now an all knowing creator is more understandable.  Yet great is your Faith that believed in this possibility before we had ChatGPT and Gemini and Claude, etc.  

This week, host Sam Ko goes upstream from our usual clinical and business topics to sit down with Dr. Roberto Malinow, emeritus professor at UC San Diego, member of both the National Academy of Sciences and the National Academy of Medicine, and one of the world's leading researchers on synaptic plasticity and NMDA receptor biology. His work has been cited more than 30,000 times, and his recent perspective piece takes a very different view of what's actually happening during a ketamine infusion.The core of this conversation is his hypothesis that ketamine works by selectively weakening hyperactive brain circuits, but only the ones actively firing while the drug is on board. It's a finding that raises some genuinely uncomfortable questions about the standard set and setting approach, and points to chronic pain treatment as a practical place to start testing these ideas clinically.You'll also hear about the brain's "disappointment center," the lateral habenula, and why it may be hyperactive in depression, the Stanford anesthesia study and what it suggests about brain activity during treatment, and a wide ranging look at consciousness, optogenetics, the gut-brain connection, and what basic science still doesn't fully understand about how psychiatric drugs work.What You'll Learn in This Episode· Revolutionary ketamine mechanism - How Dr. Malinow's hypothesis suggests ketamine works by weakening hyperactive brain circuits, but only when those specific circuits are actively firing during treatment· The disappointment center concept - Understanding the lateral habenula as the brain's disappointment center that inhibits dopamine and may be hyperactive in depression, serving an evolutionary purpose in reinforcement learning· Challenge to set and setting orthodoxy - How activating negative thoughts or painful experiences could possibly enhance therapeutic outcomes· Neuroplasticity fundamentals - How synapses can be rapidly modified and why NMDA receptors are crucial for both strengthening and weakening neural pathways, forming the basis for learning and memory· Rapid vs. delayed therapeutic effects - Why ketamine can work almost immediately while traditional antidepressants take weeks, and what this reveals about different mechanisms of action· Chronic pain treatment implications - How activating pain circuits during ketamine infusions might be more effective than current protocols, and why chronic pain could be the ideal testing ground for this hypothesis· Basic science translation - How laboratory findings about synaptic plasticity and NMDA receptors connect to real-world therapeutic applications in depression, PTSD, and pain management· Optogenetics technology - How scientists can now deliver light-sensitive proteins to specific neurons, allowing precise activation or inactivation of brain circuits to study behavior and memory· Memory manipulation research - Fascinating studies showing how specific memories can be turned on and off using targeted brain stimulation, with implications for trauma and addiction treatment· Consciousness and synaptic function - Exploring the complex relationship between individual neurons and higher-order brain functions, and why bridging these levels remains challengingEpisode 59 show notes:00:00:00 Teaser: Those hyperactive circuits…00:00:24 Episode Introduction and Guest Overview00:01:12 Sam Introduces and Welcomes Dr. Roberto Malinow00:02:41 Background: From Reed College to The MD/PhD Path00:05:17 Why Basic Science Won Out Over Clinical Medicine00:06:06 The Lecture That Started It All: Professor Rodolfo Llinás and Synapses00:06:51 How Ketamine Interacts with the NMDA Receptor00:07:47 The "Disappointment Center": What the Lateral Habenula Does and Why It Matters in Depression00:09:16 The Standard Set and Setting Approach in Outpatient Ketamine Clinics00:10:12 The Three-Part Hypothesis: Neuroplasticity, Hyperactive Circuits, and Negative Thoughts00:11:49 Written Exposure Therapy and PTSD: Priming Circuits Before the Infusion00:12:53 Chronic Pain as the Easier Testing Ground for the Hypothesis00:14:20 Activating the Pain Pathways During a Ketamine Infusion00:17:23 The Anesthesia Study (Heifets/Stanford): Why the Brain Needs to Be Active00:18:48 What Would a Human Study Design Actually Look Like?00:20:41 Animal Study Evidence Supporting the Active-Stimulus Hypothesis00:21:33 Zooming Out: Synapses, Consciousness, and the Shakespeare Analogy00:23:18 Optogenetics Explained: Using Light to Control Specific Neurons00:27:31 What Don't We Understand About Depression?00:28:29 Lateral Habenula in Animal Depression Models and Dr. Malinow's Own Experiments00:29:13 The Dystopian Scenario: Using Ketamine-Like Drugs to Wipe Out Ideas00:31:31 Common Misconceptions Clinicians Have About Synapses00:32:47 What Surprised Dr. Malinow Most About Studying Synapses00:35:15 Why Ketamine Works Rapidly While SSRIs Take Weeks00:37:30 The "Party Trick": Learning Is Neuroplasticity in Real Time00:39:13 NMDA Receptors and Their Role in Learning and Memory00:39:47 Optogenetics Research: Turning Fear Memories On and Off in Animals00:42:08 Glutamate: 90% of Synaptic Transmission Explained00:43:55 Synapses in the Gut: The Enteric Nervous System00:45:58 The Gut-Brain Connection and Future Research00:46:23 Papers Worth Reading in the Ketamine Space00:47:50 The Psychedelic Renaissance: Psilocybin, the Disappointment Center, and What's Next00:50:20 Could the Activation Hypothesis Apply to Psilocybin and MDMA as Well?00:52:57 Rapid-Fire Questions Begin00:53:19 Time Travel00:54:19 Hidden Talent00:54:48 Alternate Career00:55:42 Advice to 18-Year-Old Roberto00:56:29 Final Thoughts and Call to Action for Clinicians00:57:00 Where to Find Dr. Malinow's Research (UCSD Website)00:57:40 Sam's Closing Remarks00:58:32 Episode EndingThanks for listeningConnect with Dr. Malinow:Website: https://biology.ucsd.edu/research/faculty/rmalinowEmail: rmalinow@ucsd.edu

Hypothesis 13  

The post The Cognitive Trade-Off Hypothesis appeared first on Common Thread Church.

It's time we ask some serious questions about wisdom and maybe we need a new way of understanding it!

William Blair industrials analyst Ross Sparenblek discusses how humanoid robotics could mark a structural shift in productivity by extending AI's capabilities from digital tasks into real-world physical labor. He outlines the key forces accelerating adoption, from demographic pressures to supply chain dynamics, while highlighting both the long-term opportunity and the technical and scaling challenges still ahead.

The Qualifications.The Hypothesis.The Research Question.The Gospel.

Matt and Nic are back with a new week of news and deals. In this episode:  Spanish soccer club Osasuna hedges their relegation on Kalshi Strategy shocks people by buying the dip Is Strategy sacrificing MSTR to save STRC? Saylor bolsters his cash position What factors are dragging on the BTC price? Zcash fixes a scary inflation bug SBF formally applies for a Presidential pardon The CFTC proposes banning a subset of prediction market contracts Polymarket thinks that Kalshi is spying on them European fans in America for the World Cup are discovering Buc-ees The DATs are struggling Hester Peirce gives her farewell address Japanese banks are launching a joint stablecoin Will there be offshore interest-bearing USD stablecoins? Anthropic drops Fable  The thin model hypothesis What could pop the AI rally?

The Silurian Hypothesis asks whether a prior civilization could have risen and vanished without leaving a trace we'd recognize. The standard version looks for industrial signatures - carbon spikes, isotope anomalies, the chemical ghosts of a world that burned. But what if the most advanced technology doesn't leave that kind of mark? This episode loosens the assumption and follows it into stranger territory - systems built on principles we're only beginning to name, infrastructures that may still be running, hiding not in the geological record but in plain sight.Call in live during the show: 702-857-6939 Full archive of 1,100+ episodes: troubledminds.org

Send us Fan MailIn this episode of Skin Anarchy, Dr. Ekta Yadav sits down with Oliver Liu of Hypothesis to unpack one of the most misunderstood areas in skincare today: the microbiome. While the term has become a marketing staple, this conversation reveals just how early we still are in understanding the microbial ecosystems that shape skin health—and why most current treatments fail to reflect that complexity.Oliver reframes common conditions like acne and eczema as problems of imbalance, not simple bacterial overgrowth. In eczema, a weakened barrier, immune dysregulation, and the presence of Staphylococcus aureus create a self-reinforcing cycle of inflammation and irritation. In acne, it's not the presence of bacteria that drives breakouts—but which strains dominate. This shift challenges the long-standing idea that eliminating bacteria altogether is the solution.That insight exposes a deeper flaw in traditional treatments. Broad-spectrum approaches like benzoyl peroxide and antibiotics remove both harmful and beneficial microbes, often leading to temporary relief followed by recurrence, increased sensitivity, and long-term imbalance.The conversation then turns to a new model: precision skincare. Inspired by naturally occurring enzymes, Oliver explains how targeted approaches can selectively eliminate harmful bacteria without disrupting the surrounding ecosystem—preserving balance while addressing the root cause.This episode ultimately reframes skincare as ecosystem management, not correction.Listen to the full episode to hear Oliver break down the science of the microbiome and why the future of skincare lies in precision, not force.Shop HypothesisDon't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf!*This is a sponsored collaborationSupport the show

Is philanthropy stuck in hypothesis mode?In science, there are two kinds of research: hypothesis-driven, where you predict the outcome before you run the experiment, and exploratory, where you map the landscape and stay open to what you find. The biggest breakthroughs almost always come from the second.Meet Casey Lardner

Psychologist Julian Jaynes came up with a stunning hypothesis in 1976, that human consciousness only developed in the last 3000 years. And he seemed to have proof in ancient texts. Scholars have been picking it apart ever since and in this classic episode we join the club.See omnystudio.com/listener for privacy information.

Find Tim Constantine & Six Sensory Podcast: https://open.spotify.com/show/3LVS0BihTLQDzb5DRtpx63?si=96Isq12bSkWh94CkRuKltwYouTube: https://youtube.com/@sixsensorypodcast?si=KXoO5h47Y1RErmoSPatreon: ⁠⁠⁠patreon.com/TimConstantine⁠Become a supporter of this podcast: https://www.spreaker.com/podcast/cult-of-conspiracy--5700337/support.

This episode is presented by Create A Video – John Konrad is the CEO of gCaptain, a maritime news website. He is also a former US Merchant Marine, Ship Captain, and member of the Pentagon press corps. His theory on developments in the Strait of Hormuz is that the White House is in no hurry to open the waterway as part of a larger play to extract concessions from global leaders, academics, think tanks, lobbyists, and "the DC Swamp" who have stymied his effort to restore maritime supremacy. Subscribe to the podcast at: https://ThePetePod.com/ All the links to Pete's Prep are free: https://patreon.com/petekalinershow Media Bias Check: GroundNews promo code! Advertising and Booking inquiries: Pete@ThePeteKalinerShow.com Get exclusive content here!: https://thepetekalinershow.com/See omnystudio.com/listener for privacy information.