Podcasts about Hypothesis

Sponsor Links:This episode is brought to you by Saily. If you love to travel, Saily could be your new best friend. Check out details and our special offer by visiting www.saily.com/spacenuts and use the coupon code SPACENUTS at checkout. Surf the web with Saily, wherever you go.Curious Queries: Exploring Cosmic Mysteries and Stellar ScienceIn this captivating Q&A episode of Space Nuts, hosts Heidi Campo and Professor Fred Watson dive into an array of intriguing questions from listeners that span the realms of astrophysics and planetary science. From the challenges of Kessler Syndrome to the mysteries surrounding black holes, this episode is a treasure trove of insights that will ignite your curiosity about the cosmos.Episode Highlights:- Kessler Syndrome and Space Debris: The episode kicks off with a question from Greg in Minnesota about the potential dangers of Kessler Syndrome and what measures are being taken to mitigate space debris. Fred explains the growing issue of orbital congestion and the importance of ensuring that spacecraft can be deorbited safely to prevent catastrophic collisions in space.- The Thickness of Venus's Atmosphere: Greg's second question prompts a fascinating discussion about why Venus has such a dense atmosphere. Fred delves into the composition of Venus's atmosphere and compares it to Earth's, exploring the unique conditions that allow it to hold such a thick layer of gases.- Stars, Black Holes, and Planetary Formation: The hosts then address an audio question from young Henrique, who is curious about the relationship between stars and black holes. Fred explains the delicate balance of forces that allow stars to exist and how massive stars can ultimately collapse into black holes, along with the possibility of planets existing around these enigmatic objects.- Density Comparisons: Protons vs. Black Holes: The episode wraps up with a question from East Hawk regarding the density of black holes compared to protons. Fred clarifies the calculations involved and discusses the concept of density in the context of black holes, revealing the extraordinary nature of these cosmic phenomena.For more Space Nuts, including our continuously updating newsfeed and to listen to all our episodes, visit our website. Follow us on social media at SpaceNutsPod on Facebook, X, YouTube Music Music, Tumblr, Instagram, and TikTok. We love engaging with our community, so be sure to drop us a message or comment on your favorite platform.If you'd like to help support Space Nuts and join our growing family of insiders for commercial-free episodes and more, visit spacenutspodcast.com/aboutStay curious, keep looking up, and join us next time for more stellar insights and cosmic wonders. Until then, clear skies and happy stargazing.Got a question for our Q&A episode? https://spacenutspodcast.com/amaBecome a supporter of this podcast: https://www.spreaker.com/podcast/space-nuts-astronomy-insights-cosmic-discoveries--2631155/support.

"The Great Hypothesis" explores the fundamental question of existence and origins, arguing that there must be a single source for all life and reality. It posits that without acknowledging the existence of God, one cannot logically explain the emergence of reality or maintain a coherent moral worldview. The author contrasts the belief in God with atheistic and legalistic perspectives, emphasizing that without God, society is left with the law of the jungle, where might makes right. The church provides a moral framework and community for believers, while non-believers struggle with distrust and lack of common purpose.

Why The One Reality Hypothesis Fails is offered as an explanation why science has become divided between a set of data driven physical or hard sciences and a set of narrative driven social or soft sciences that few consider part of the scientific community anymore.The problem is not the sciences, per se, so much as the reality these fields represent. The idea that reality is all one piece and all science studies the same substance, regardless of if they are a material science or part of the humanities. The reader can argue in defense of the One Reality Hypothesis, if they wish, but it is easily proved that an alternative hypothesis produces better results. The choice is between a reality that is logically incoherent and restricted to highly artificial environments, or a reality that hardens the soft science, and produces results in an environment that is far more humane.

fter a massive European break, wedding, honeymoon, the works, I knew I couldn't just ease back into life and hope for momentum to return on its own. In this episode, I walk you through the exact protocols I'm using to rebuild discipline: a month-long training system, my morning routine, and why I believe structure isn't restrictive, it's liberating. This is about reclaiming control and setting the tone for the next few months of my life. No fluff, no hype, just systems that work. Aka Effective Philosophy.(00:00) – The Return: Coming Back with Purpose(00:38) – Why Discipline Starts with Systems(01:03) – What Holidays Took Away (And Why That's Okay)(01:52) – July Protocol: A System to Reset the Body & Mind(02:30) – Training Cadence vs. Unrealistic Optimisation(03:09) – The Two-Part Protocol: Strength + Morning Rhythm(03:46) – Reality Check: 30s vs. 20s Strength Goals(04:47) – The Hypothesis: 5x5 Training as a Reset Tool(06:04) – Weekly Breakdown: Simplicity with Precision(07:33) – The Four-Week Ramp-Up Plan(09:06) – How to Push Without Breaking(10:04) – Defining Your Training Max (Not Your Ego Max)(11:04) – Running, Flexibility, and Leaving Room for Life(12:05) – Protocols vs. Fancy: Just Show Up(12:24) – The Morning Routine: Grounding the Day with Intent(13:06) – Win the Morning, Win the War(14:01) – Practical Morning Breakdown & Why It Works(16:22) – Why Prepping the Day Before is the Real Discipline(17:46) – 8 Days In: Results and Reflections(18:23) – Final Thoughts: Be Scientific, Be Accountable(18:52) – Outro: Discipline Is a Protocol, Not a MoodConnect with Mere Mortals:Website: https://www.meremortalspodcast.com/Discord: https://discord.gg/jjfq9eGReUTwitter/X: https://twitter.com/meremortalspodsInstagram: https://www.instagram.com/meremortalspodcasts/TikTok: https://www.tiktok.com/@meremortalspodcast Connect with Mere Mortals:Website: https://www.meremortalspodcasts.com/Discord: https://discord.gg/jjfq9eGReUTwitter/X: https://twitter.com/meremortalspodsInstagram: https://www.instagram.com/meremortalspodcasts/TikTok: https://www.tiktok.com/@meremortalspodcastsValue 4 Value Support:Boostagram: https://www.meremortalspodcasts.com/supportPaypal: https://www.paypal.com/paypalme/meremortalspodcast

Are the AI models you use today imposters?Please watch the intro video we did before this: https://www.youtube.com/watch?v=o1q6Hhz0MAgIn this episode, hosts Dr. Tim Scarfe and Dr. Duggar are joined by AI researcher Prof. Kenneth Stanley and MIT PhD student Akash Kumar to discuss their fascinating paper, "Questioning Representational Optimism in Deep Learning."Imagine you ask two people to draw a perfect skull. One is a brilliant artist who understands anatomy, the other is a machine that just traces the image. Both drawings look identical, but the artist understands what a skull is—they know where the mouth is, how the jaw works, and that it's symmetrical. The machine just has a tangled mess of lines that happens to form the right picture.An AI with an elegant representation, has the building blocks to generate truly new ideas.The Path Is the Goal: As Kenneth Stanley puts it, "it matters not just where you get, but how you got there". Two students can ace a math test, but the one who truly understands the concepts—instead of just memorizing formulas—is the one who will go on to make new discoveries.The show is a mixture of 3 separate recordings we have done, the original Patreon warmup with Tim/Kenneth, the Tim/Keith "Steakhouse" recorded after the main interview, then the main interview with Kenneth/Akarsh/Keith/Tim. Feel free to skip around. We had to edit this in a rush as we are travelling next week but it's reasonably cleaned up. TOC:00:00:00 Intro: Garbage vs. Amazing Representations00:05:42 How Good Representations Form00:11:14 Challenging the "Bitter Lesson"00:18:04 AI Creativity & Representation Types00:22:13 Steakhouse: Critiques & Alternatives00:28:30 Steakhouse: Key Concepts & Goldilocks Zone00:39:42 Steakhouse: A Sober View on AI Risk00:43:46 Steakhouse: The Paradox of Open-Ended Search00:47:58 Main Interview: Paper Intro & Core Concepts00:56:44 Main Interview: Deception and Evolvability01:36:30 Main Interview: Reinterpreting Evolution01:56:16 Main Interview: Impostor Intelligence02:11:15 Main Interview: Recommendations for AI ResearchREFS:Questioning Representational Optimism in Deep Learning:The Fractured Entangled Representation HypothesisAkarsh Kumar, Jeff Clune, Joel Lehman, Kenneth O. Stanleyhttps://arxiv.org/pdf/2505.11581Kenneth O. Stanley, Joel LehmanWhy Greatness Cannot Be Planned: The Myth of the Objectivehttps://amzn.to/44xLaXKOriginal show with Kenneth from 4 years ago:https://www.youtube.com/watch?v=lhYGXYeMq_EKenneth Stanley is SVP Open Endedness at Lila Scienceshttps://x.com/kenneth0stanleyAkarsh Kumar (MIT)https://akarshkumar.com/AND... Kenneth is HIRING (this is an OPPORTUNITY OF A LIFETIME!)Research Engineer: https://job-boards.greenhouse.io/lila/jobs/7890007002Research Scientist: https://job-boards.greenhouse.io/lila/jobs/8012245002TRANSCRIPT:https://app.rescript.info/public/share/W_T7E1OC2Wj49ccqlIOOztg2MJWaaVbovTeyxcFEQdU

What if today's incredible AI is just a brilliant "impostor"? This episode features host Dr. Tim Scarfe in conversation with guests Prof. Kenneth Stanley (ex-OpenAI), Dr. Keith Duggar (MIT), and Arkash Kumar (MIT).While AI today produces amazing results on the surface, its internal understanding is a complete mess, described as "total spaghetti" [00:00:49]. This is because it's trained with a brute-force method (SGD) that's like building a sandcastle: it looks right from a distance, but has no real structure holding it together [00:01:45].To explain the difference, Keith Duggar shares a great analogy about his high school physics classes [00:03:18]. One class was about memorizing lots of formulas for specific situations (like the "impostor" AI). The other used calculus to derive the answers from a deeper understanding, which was much easier and more powerful. This is the core difference: one method memorizes, the other truly understands.The episode then introduces a different, more powerful way to build AI, based on Kenneth Stanley's old experiment, "Picbreeder" [00:04:45]. This method creates AI with a shockingly clean and intuitive internal model of the world. For example, it might develop a model of a skull where it understands the "mouth" as a separate component it can open and close, without ever being explicitly trained on that action [00:06:15]. This deep understanding emerges bottom-up, without massive datasets.The secret is to abandon a fixed goal and embrace "deception" [00:08:42]—the idea that the stepping stones to a great discovery often don't look anything like the final result. Instead of optimizing for a target, the AI is built through an open-ended process of exploring what's "interesting" [00:09:15]. This creates a more flexible and adaptable foundation, a bit like how evolvability wins out in nature [00:10:30].The show concludes by arguing that this choice matters immensely. The "impostor" path may be hitting a wall, requiring insane amounts of money and energy for progress and failing to deliver true creativity or continual learning [00:13:00]. The ultimate message is a call to not put all our eggs in one basket [00:14:25]. We should explore these open-ended, creative paths to discover a more genuine form of intelligence, which may be found where we least expect it.REFS:Questioning Representational Optimism in Deep Learning:The Fractured Entangled Representation HypothesisAkarsh Kumar, Jeff Clune, Joel Lehman, Kenneth O. Stanleyhttps://arxiv.org/pdf/2505.11581Kenneth O. Stanley, Joel LehmanWhy Greatness Cannot Be Planned: The Myth of the Objectivehttps://amzn.to/44xLaXKOriginal show with Kenneth from 4 years ago:https://www.youtube.com/watch?v=lhYGXYeMq_EKenneth Stanley is SVP Open Endedness at Lila Scienceshttps://x.com/kenneth0stanleyAkarsh Kumar (MIT)https://akarshkumar.com/AND... Kenneth is HIRING (this is an OPPORTUNITY OF A LIFETIME!)Research Engineer: https://job-boards.greenhouse.io/lila/jobs/7890007002Research Scientist: https://job-boards.greenhouse.io/lila/jobs/8012245002Tim's Code visualisation of FER based on Akarsh repo: https://github.com/ecsplendid/ferTRANSCRIPT: https://app.rescript.info/public/share/YKAZzZ6lwZkjTLRpVJreOOxGhLI8y4m3fAyU8NSavx0

NYU Long/Buzsakiラボの、藤島悠貴さん(@yfujishima_) さんがゲスト。近況アップデート、最近出た唄うマウスの行動解析論文、Krakauerのオピニオン論文を元にした議論、など (6/15 収録)Show Notes (番組HP):Michael LongGyuri BuzsákiPaul GlimcherDmitriy AronoがHHMIとったAttila LosonczyAlex WilliumsFlatiron InstituteEero Simoncelliダグラス・ウェバーのコーヒーミルSimonsさん亡くなったSimonsのブリッジグラントが再編成されてFellow-to-Faculty (FtF)にTime warpingのメソッドInternational Brain Laboratory (IBL)Caleb Kemere唄うマウスの行動解析論文: Fujishima and Long, 2025（補足）サーマルカメラを直接SLEAPに突っ込む: 16bitで保存された生データに対し、背景除去などいくつかのヒューリスティックな前処理を行った上で、8bit動画に変換し、SLEAPに流しています。詳細はメソッド欄をご参照ください。（藤島）コスタリカでのフィールドリサーチティンバーゲンは、species-specific behaviorを、その種に特有の本能的な行動と定義しており、学習を必要とせず、生得的に備わっている（ただし、学習によって全く変化しないという意味ではない）定型化された行動パターン（action patterns）を指している。一連のパターン化された動きは、特定の外界刺激（releasing stimuli）によって“解放”（release）されることで引き起こされるとされている。また、これらの行動は外的刺激だけでなく、ホルモン状態などの内的要因にも影響を受ける。1951年に刊行された『The Study of Instinct』において、ティンバーゲンは自身の代表的なイトヨの研究をはじめとした具体例を通じて、これらの現象について詳述しており、この本は、1940〜50年代の英語圏において主流であった実験心理学、特にパブロフらの影響を受けた行動主義（内的状態に依拠せず、観察可能な行動のみを実験室で科学的に扱う立場）に対して、一種のアンチテーゼを提示するものとなった（らしい）。(藤島)歌い返すのにneocortex (orofacial motor cortex)が必要ということを示した論文 Arkarup Banerjee lab2wkだまるのcitation歌う姿勢（YouTubeビデオ)David Schneiderのポスドク時代のcollorary dischargeに関する論文Neuroscience needs behavior: correcting a reductionist biasJohn KrakauerMarrの3つのレベル — computation, algorithm, implementationHubel and Wiesel68年〜などと言ってますが、正確には方位検出の初出が1959論文、 algorithm (+implementation予測)の提示が1962論文 (Fig19)。(補足)computationが線を検出すること、algorithmがいくつかの丸型の受容野を持った細胞が一つの細胞に入力することで線に対応する受容野を作りうるという模式図、そしてimplementationが丸型需要野を持つLGNの細胞がV1L4にconvergeすること。(萩)ImplementationのH&W予測が凡そ正しいことを示せた2018年のScanziani論文Degeneracy: この文脈では同じcomputationを成り立たせるalgorithmが複数ありうること、もしくは同じalgorithmを成り立たせるimplementationが複数あること。Eve Marderはよく、あるneuronのoutputのパターンが同じでもそのneuronにinputする細胞群のパターンが異なりうる、という文脈でよくcircuit degeneracyと書いている。Neuroscience needs evolutionNeuroscience needs behaviorのオマージュ: evolution(先述)、psychology, Network science 全然違うNeuroscience needs behaviorCris Niell哺乳類とは全く独立して進化したタコの目の仕組みEve Marderが”toleranceと”mechanism”の粒度について語るポッドキャスト回 (Night Science)Johnson-Lindenstrauss Lemma: 高次元のデータを低次元に写しても、データポイント間のpair-wise distanceはほぼ保たれるという定理。(Chen and Pesaran, 2021 に軽くmentionあり)Krakauer兄弟同時出演ポッドキャスト回 (Brain Inspored)Current Biology: John and David KrakauerSchultz, Dayan, Montague - ドーパミン界の金字塔(ほぼreview)論文の裏話 (JNSのシュルツの自伝、pdf直リンク)Hodgikin-Huxley model論文結果としてNaとKチャネルのサブユニット数や機能を予測していたYael Niv氏の似た趣旨の論文Nathaniel DawNIHの論文をオープンにしないといけないという新しいポリシーAllen Instituteのbehavior & ephysオープンデータセットKen Harris日本がメリケン脱出組に700MHHMI Hannah Gray FellowshipやめたAng Leeさん（映画監督）ハルクに変身した主人公が怒りに任せて研究所を破壊するシーンDeepMindのLLMが医者AIがリアルな医者の診断能力を超えたという論文: text chatという点は留意海馬の表彰はgoal directedなaction planであることを示した論文Tank研の論文Dick Tsienディスカッションとても楽しかったです。物事を理解するとはどういうことなのか、それこそジョンがどこかで「科学者は哲学し続けなければならない」と言っていたのを思い出しました。またオフラインでも議論できることを楽しみにしてます。 (藤島)などといっていたら中東+メリケン戦争みたいになってしまい大変残念。Weizmannではミサイルでラボが7-8個(物理的に)消し飛んだとのこと。やれやれ。壁か卵のどちらかでいうと常に卵の側でいたい、という気持ちはあるのだが、100%の壁も、100%の卵も、そんな完璧な物はどこにも存在しないのだろう。ピース。(萩)グラントの評価ではHypothesis drivenな研究が好まれるらしいのでNatural behaviorの研究を書くのはより挑戦的な印象。でも探索的な研究はもっと増えてほしいですね(脇)

Hypothesis 4  

Could mass unrest be timed like tides? Do hidden solar pulses reprogram civilization beneath our awareness? What if every apocalypse is just a reset, coded in cycles we've forgotten how to read? The sun may not just power life. It may script it.​​GET THE MUSIC HERE! -- ​https://troubledfans.com/collections/featured-launch-products/products/rogue-tulpas-troubled-minds-greatest-hits-a-this-is-a-digital-download​​If you are having a mental health crisis and need immediate help, please go to ​ ​​https://troubledminds.org/help/ and call somebody right now. Reaching out for support is a sign of strength. ​ ​​​LIVE ON Digital Radio! Http://bit.ly/40KBtlW ​ ​ ​​http://www.troubledminds.net or ​ ​​https://www.troubledminds.org ​ ​Support The Show! ​ ​ ​https://www.spreaker.com/podcast/troubled-minds-radio--4953916/support ​ ​​https://ko-fi.com/troubledminds ​ ​​https://patreon.com/troubledminds ​ ​​https://www.buymeacoffee.com/troubledminds ​ ​​https://troubledfans.com ​ ​Friends of Troubled Minds! - ​ ​ ​https://troubledminds.org/friends ​ ​Show Schedule Sun--Tues--Thurs--Fri 7-10pst ​iTunes - ​ ​​https://apple.co/2zZ4hx6 ​Spotify - ​ ​​https://spoti.fi/2UgyzqM ​TuneIn - ​ ​​https://bit.ly/2FZOErS ​Twitter - ​ ​​https://bit.ly/2CYB71U​​​----------------------------------------​​https://troubledminds.substack.com/p/the-solar-trigger-hypothesis-charting​​https://x.com/BrianRoemmele/status/1936970565308624990​​https://en.wikipedia.org/wiki/Alexander_Chizhevsky​​https://en.wikipedia.org/wiki/Chronobiology​​https://en.wikipedia.org/wiki/Revolutionary_wave​​https://medium.com/@brookeganster75/the-black-sun-occult-symbolism-esoteric-power-and-historical-roots-230252dc1405​​https://biblehub.com/joshua/10-13.htm​​https://scienceblog.com/can-group-meditation-prevent-violent-crime-surprisingly-data-suggests-yes/​​https://en.wikipedia.org/wiki/Quetzalc%C5%8D%C4%81tl​​https://www.crystalinks.com/blacksun.html

Join us for a compelling episode of the ESVS Podcast as we explore the sex disparities in aortic disease with two experts in aortic surgery in women — Dr. Carlota Fernandez-Prendes and Dr. Anna-Louise Pouncey.In this episode, we discuss why women remain under-represented in clinical trials, which subgroups may benefit most from targeted screening, and why women face higher complication rates after both open and endovascular aneurysm repair in the immediate perioperative period. We also examine the underlying causes of these differences and how vascular surgeons can optimise outcomes for their female patients.This episode underscores the importance of heightened clinical awareness and tailored research. Stay tuned until the end for key insights on aortic aneurysm in women.Referenced articles:Talvitie M, Åldstedt-Nyrønning L, Stenman M, Roy J, Cohnert T, Hultgren R. Women with large intact abdominal aortic aneurysms remain untreated. J Vasc Surg. 2023;78(3):657–667. doi:10.1016/j.jvs.2023.05.025.O'Donnell TFX, Patel PB, Marcaccio CL, Dansey KD, Swerdlow NJ, Rastogi V, Patel VI, Beck AW, Zettervall SL, Schermerhorn ML. Outcomes of complex endovascular treatment of post-dissection aneurysms. Eur J Vasc Endovasc Surg. 2023;66(1):58–66. doi:10.1016/j.ejvs.2023.04.013.Gorgatti F, Nana P, Panuccio G, Rohlffs F, Torrealba JI, Kölbel T. Post-dissection thoraco-abdominal aortic aneurysm managed by fenestrated or branched endovascular aortic repair. Eur J Vasc Endovasc Surg. 2024;68(3):325–334. doi:10.1016/j.ejvs.2024.04.041.Huckaby LV, Sultan I, Trimarchi S, Leshnower B, Chen EP, Brinster DR, et al. Sex-based aortic dissection outcomes from the International Registry of Acute Aortic Dissection. Ann Thorac Surg. 2022;113(2):498–505. doi:10.1016/j.athoracsur.2021.03.100.Tenorio ER, Oderich GS, Farber MA, Schneider DB, Timaran CH, Schanzer A, et al. Outcomes of endovascular repair of chronic postdissection compared with degenerative thoracoabdominal aortic aneurysms using fenestrated-branched stent grafts. J Vasc Surg. 2020;72(3):822–836. doi:10.1016/j.jvs.2019.10.091.Lo RC, Bensley RP, Hamdan AD, Wyers M, Adams JE, Schermerhorn ML; Vascular Study Group of New England. Gender differences in abdominal aortic aneurysm presentation, repair, and mortality in the Vascular Study Group of New England. J Vasc Surg. 2013;57(5):1261–1268.e5. doi:10.1016/j.jvs.2012.11.039.Lancaster EM, Gologorsky R, Hull MM, Okuhn S, Solomon MD, Avins AL, et al. The natural history of large abdominal aortic aneurysms in patients without timely repair. J Vasc Surg. 2022;75(1):109–117. doi:10.1016/j.jvs.2021.07.125.Bulder RMA, Tedjawirja VN, Hamming JF, Koelemay MJ, Balm R, Lindeman JHN; on behalf of the study group collaborators. Hypothesis of the high mortality of female patients following elective open abdominal aortic aneurysm repair. Eur J Vasc Endovasc Surg. 2022;63(5):773–774. doi:10.1016/j.ejvs.2022.01.018.Pouncey AL, David M, Morris RI, Ulug P, Martin G, Bicknell C, Powell JT. Systematic review and meta-analysis of sex-specific differences in adverse events after open and endovascular intact abdominal aortic aneurysm repair: consistently worse outcomes for women. Eur J Vasc Endovasc Surg. 2021;62(3):367–378. doi:10.1016/j.ejvs.2021.05.029.O'Donnell TFX, Verhagen HJ, Pratesi G, Pratesi C, Teijink JAW, Vermassen FEG, et al. Female sex is associated with comparable 5-year outcomes after contemporary endovascular aneurysm repair despite more challenging anatomy. J Vasc Surg. 2019;70(6):1782–1792.e2. doi:10.1016/j.jvs.2019.05.065.

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Hypothesis 4  

We're told rookie cards matter most. But what happens when a player writes their legacy wearing a different uniform?In this episode, I take a personal and collector-first look at why Tyrese Haliburton's Pacers cards might matter more than his Kings rookies. This isn't about ignoring the rookie card—it's about questioning hobby programming, thinking independently, and considering what actually connects you to a card.I share the real-time perspective of being a fan during the most meaningful Pacers run of my life and how that clarity has reshaped the way I see Haliburton's card catalog.You'll hear about:What cards are available and which ones aren'tThe difference between collector-controlled and commodity cardsWhy emotional connection matters more than labelsHow this applies beyond HaliburtonIt's not a take—it's a question. What if the best card isn't the first one?This episode is for anyone looking to find ways to land cards with collectors through trust.Start your 7 day free trial of Stacking Slabs Patreon Today[Distributed on Sunday] Sign up for the Stacking Slabs Weekly Rip Newsletter using this linkFollow Stacking Slabs: | Twitter | Instagram | Facebook | Tiktok

Hypothesis 3  

Send us a textLet's talk the age of serial killers! Pulitzer Prize winner Caroline Fraser joins me to talk her book Murderland: Crime and Bloodlust in the Time of Serial Killers. Buy MurderlandCheck out Caroline's websiteSupport the show

Hypothesis 3  

Karen Kelly is a sales strategist, speaker, and founder of K2 Performance Consulting, where she helps B2B companies sell with confidence, clarity, and purpose. In this episode of Make It Happen Mondays, John Barrows sits down with Karen for a tactical and inspiring conversation that covers everything from her immigrant upbringing and biology background to coaching, confidence, and creating safe spaces for buyers.They explore her concept of hypothesis selling, the importance of showing up with perspective during qualification, and how reps can catch that elusive “sales groove.” Karen shares actionable coaching strategies, the power of preparation, and how to detach from what others think in order to show up more authentically in sales conversations.The episode also highlights Karen's advocacy for women in sales—and why opening more doors in the industry isn't just the right thing to do, it's smart business. This one is packed with wisdom, heart, and practical advice for anyone serious about elevating their sales game.Are you interested in leveling up your sales skills and staying relevant in today's AI-driven landscape? Visit www.jbarrows.com and let's Make It Happen together!Connect with John on LinkedIn: https://www.linkedin.com/in/johnbarrows/Connect with John on IG: https://www.instagram.com/johnmbarrows/Check out John's Membership: https://go.jbarrows.com/pages/individual-membership?ref=3edab1 Join John's Newsletter: https://www.jbarrows.com/newsletterConnect with Karen on LinkedIn: https://www.linkedin.com/in/karen-kelly-sales-trainer-/Connect with Karen on IG: https://www.instagram.com/k2perform/Check out Karen's Websites: https://www.k2perform.com/, https://k2salesacademy.com/ and https://k2perform.webflow.io/webinar-series-2#registerednurse

Ecclesiastes 2:1-11

Et si vivre avec une personne dépressive pouvait, au fil du temps, vous rendre vulnérable à votre tour ? C'est la question soulevée par une étude étonnante publiée dans la revue Exploratory Research and Hypothesis in Medicine. Les chercheurs s'y sont intéressés à un acteur discret mais essentiel de notre bien-être mental : notre microbiote intestinal.Le microbiote, c'est cet écosystème de milliards de bactéries qui peuplent notre tube digestif. Il influence notre digestion, notre immunité, et… notre humeur. Depuis quelques années, les scientifiques parlent même d'un "axe intestin-cerveau", révélant que nos intestins jouent un rôle dans la régulation du stress, de l'anxiété et des troubles dépressifs.L'étude s'est penchée sur des couples vivant ensemble depuis plus de six mois. Les chercheurs ont découvert que, progressivement, les partenaires en couple voyaient leur microbiote intestinal devenir de plus en plus semblable. Comment ? Par des habitudes partagées : alimentation, rythme de vie, contact physique, échanges de salive, ou même exposition aux mêmes environnements bactériens. Résultat : le microbiote de l'un influence celui de l'autre.Ce qui interpelle, c'est que ce processus peut aussi favoriser la transmission de déséquilibres. Si l'un des deux souffre de troubles anxieux ou dépressifs, son microbiote peut être altéré — on parle alors de "dysbiose". Et en partageant ce microbiote perturbé, le partenaire sain pourrait, lui aussi, voir apparaître des symptômes liés à ces troubles. Autrement dit, la dépression pourrait avoir une dimension… microbiologique.Il ne s'agit pas ici de dire que la dépression est "contagieuse" au sens classique du terme, mais plutôt que le terrain biologique peut se synchroniser entre deux partenaires. Et cette synchronisation peut inclure des fragilités. Cela vient compléter ce que l'on savait déjà sur l'impact psychologique du quotidien partagé avec une personne en souffrance : fatigue mentale, empathie épuisée, repli sur soi. Mais ici, c'est le corps lui-même qui s'ajuste, parfois au détriment de l'équilibre mental.Ce constat ouvre de nouvelles pistes en santé mentale : soigner la dépression dans un couple pourrait aussi passer par une approche conjointe, y compris au niveau intestinal. Et cela rappelle que nos relations les plus intimes façonnent, bien plus qu'on ne l'imagine, notre santé physique et mentale.Une simple vie commune pourrait donc modifier, en profondeur, ce qui se joue dans nos entrailles… et dans notre esprit. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

My name is Trevor, I'm a clinical neuroscience researcher trying to answer the big questions like "Who are we?" and "Why are we here?"This series of mini episodes will explore these concepts from my new book- God's Eye View. Today's episode highlights the RNA World Hypothesis, otherwise known as science's best attempt to answer the question: "Where did life come from?"He argues that free will is an illusion, but I'm not convinced, are you? Buy the book and support Fringe Radio Network with this link: https://amzn.to/4d7p6qRBuy the Audiobook: https://www.audible.com/pd/Gods-Eye-View-Audiobook/B0F55K2GT1?source_code=ASSGB149080119000H&share_location=pdpWant to publish a book? Check out my publisher https://hemisphericpress.com/Check out my substack: https://hemisphericpress.substack.com/

Art Bell - Peter Ward - Rare Earth Hypothesis

Demetrios and Mohan Atreya break down the GPU madness behind AI — from supply headaches and sky-high prices to the rise of nimble GPU clouds trying to outsmart the giants. They cover power-hungry hardware, failed experiments, and how new cloud models are shaking things up with smarter provisioning, tokenized access, and a whole lotta hustle. It's a wild ride through the guts of AI infrastructure — fun, fast, and full of sparks!Big thanks to the folks at Rafay for backing this episode — appreciate the support in making these conversations happen!// BioMohan is a seasoned and innovative product leader currently serving as the Chief Product Officer at Rafay Systems. He has led multi-site teams and driven product strategy at companies like Okta, Neustar, and McAfee. // Related LinksWebsites: https://rafay.co/~~~~~~~~ ✌️Connect With Us ✌️ ~~~~~~~Catch all episodes, blogs, newsletters, and more: https://go.mlops.community/TYExploreMLOps Swag/Merch: [https://shop.mlops.community/]Connect with Demetrios on LinkedIn: /dpbrinkmConnect with Mohan on LinkedIn: /mohanatreyaTimestamps:[00:00] AI/ML Customer Challenges[04:21] Dependency on Microsoft for Revenue[09:08] Challenges of Hypothesis in AI/ML[12:17] Neo Cloud Onboarding Challenges[15:02] Elastic GPU Cloud Automation[19:11] Dynamic GPU Inventory Management[20:25] Terraform Lacks Inventory Awareness[26:42] Onboarding and End-User Experience Strategies[29:30] Optimizing Storage for Data Efficiency[33:38] Pizza Analogy: User Preferences[35:18] Token-Based GPU Cloud Monetization[39:01] Empowering Citizen Scientists with AI[42:31] Innovative CFO Chatbot Solutions[47:09] Cloud Services Need Spectrum

Once upon a time a young lady had an idea. An idea that two popular actors are deeply similar in their acting, but one of them is taken way more seriously.That's it for that voice, we talk a lot about that and about the Nic Cage and Keanu movies we watched. We also visit the cage for another round of "Caleb almost did do get a degree for this"

Hypothesis 3  

It's Paul's birthday, and he's throwing the coolest science-themed party ever— But when Ozzie arrives and hears all the party excitement, he suddenly feels a little nervous about going in alone.With a deep breath in... and a slow breath out, Ozzie remembers a calming trick he learned— the 4,7,8 breathing technique! He gathers his courage, walks in, and soon giggles, plays games, and celebrates with all his friends.The best part? A very special guest scientist stops by to show the kids amazing science tricks based on the weather! She teaches them how fun it is to ask questions and explore the world around them. This episode is full of birthday cheer, friendship, bravery, and a little bit of science magic! So grab your safety goggles, Kiddywinks—let's party like a scientist!

Could intelligence be less a product of evolution and more a signal embedded in matter itself - resonating through birds, mammals, and octopuses alike? If consciousness isn't confined to biology, but seeded, recalled, or received, are we merely one expression among many in a planetary network designed to awaken?​​​If you are having a mental health crisis and need immediate help, please go to ​​https://troubledminds.org/help/ and call somebody right now. Reaching out for support is a sign of strength. ​ ​LIVE ON Digital Radio! Http://bit.ly/40KBtlW ​ ​​http://www.troubledminds.net or ​​https://www.troubledminds.org ​ ​Support The Show! ​​https://www.spreaker.com/podcast/troubled-minds-radio--4953916/support ​​https://ko-fi.com/troubledminds ​​https://patreon.com/troubledminds ​​https://www.buymeacoffee.com/troubledminds ​​https://troubledfans.com ​ ​Friends of Troubled Minds! - ​​https://troubledminds.org/friends ​ ​Show Schedule Sun--Tues--Thurs--Fri 7-10pst ​iTunes - ​​https://apple.co/2zZ4hx6 ​Spotify - ​​https://spoti.fi/2UgyzqM ​TuneIn - ​​https://bit.ly/2FZOErS ​Twitter - ​​https://bit.ly/2CYB71U​----------------------------------------​​https://troubledminds.substack.com/p/the-primordial-signal-trinary-cognition​​https://www.wired.com/story/intelligence-evolved-at-least-twice-in-vertebrate-animals/​​https://plato.stanford.edu/entries/panpsychism/​​https://www.scientificamerican.com/article/is-consciousness-universal/​​https://en.wikipedia.org/wiki/Noosphere​​https://en.wikipedia.org/wiki/Gaia_hypothesis

Dear RLR Family,We bring you RLR 179 where we discuss the complex subject of the HYPOTHESIS of the GENEALOGICAL ADAM and  EVE.Genealogical ancestry is not genetic ancestry, and that genealogical ancestry is more important in establishing that Adam and Eve could have been ancestors to the entire human race alive today and that Adam and Eve could have lived a mere 6,000 years ago.Thus, the traditional de novo account of the creation of Adam and Eve could have occurred alongside evolution of human descent. This leaves intact the Genesis account and allows room for evolutionary science. The Genealogical Hypothesis Summarized1)        Adam and Eve could have lived as recently as 6,000 years agio in the Middle East.2)        Adam and Eve are the genealogical ancestors of the entire human race as it exists today.3)        Adam and Eve were created de novo by an act of God from dust and Adam's rib.4)        There was interbreeding between the lines of Adam and Eve and those that were found                outside of the Garden.5)        The main findings of evolutionary science can be reconciled with traditional readings of               Genesis where those outside of the Garden would have shared common descent with the great           apes, and humans are descended not from an original human couple, but from a larger           population that included these people from outside of the Garden.  

Hypothesis 2  

Can the appearances of Jesus be explained away as hallucinations? Two leading doctors offer a medical critique. Dr. Harold Koenig is one of the world's experts in the intersection of science, theology, and spirituality. He has written 575 peer-reviewed scientific journals and 55 books. Craig Fowler, M.D., is Professor & Chair of Surgery at the Campbell University School of Osteopathic Medicine. He has received both Best Doctor in America and US Top Ophthalmology awards.Duke University Center for Spirituality, Theology, and Health (https://spiritualityandhealth.duke.edu/)READ: Evidence that Demands a Verdict (https://amzn.to/3rtbGiP)*Get a MASTERS IN APOLOGETICS or SCIENCE AND RELIGION at BIOLA (https://bit.ly/3LdNqKf)*USE Discount Code [SMDCERTDISC] for $100 off the BIOLA APOLOGETICS CERTIFICATE program (https://bit.ly/3AzfPFM)*See our fully online UNDERGRAD DEGREE in Bible, Theology, and Apologetics: (https://bit.ly/448STKK)FOLLOW ME ON SOCIAL MEDIA: Twitter: https://twitter.com/Sean_McDowell TikTok: @sean_mcdowell Instagram: https://www.instagram.com/seanmcdowell/

If you've heard of brain retraining, you've probably heard of Ashok Gupta. He is the founder of the AIR Neuro Immune Hypothesis which explores the root causes of our symptoms, chronic fatigue, pain, anxiety and more and provides a science-based, true healing. If you've ever been told it's all in your head, you can't heal, or if you feel like you've tried everything without the results you so desperately seek, you need to know about Amygdala and Insula Retraining. It's not all in your head, it's in your brain, and nervous system. Ashok is an internationally renowned Speaker, Filmmaker & Health Practitioner, and founder of the Gupta Program, who has dedicated his life to supporting people through chronic illness, and achieving their potential. You can learn more about him by going to his website: https://guptaprogram.com/ or you can connect with him on instagram at https://www.instagram.com/guptaprogram     Additional Resources:

What happens when the product science principles are applied to a conference organization?  You get Product Collective, now called Mind The Product by Pendo.io. Through events like INDUSTRY: The Product Conference, along with resources such as a member hub and over 100 hours of past conference videos, product professionals across the globe find community, learn, and improve their work.  Rather than AI being the end-all-be-all answer, Mike hopes that AI will be used to integrate both qualitative insights from empathetic customer interactions and quantitative data. This evidence-based approach involves testing strategies through small experiments, learning from the outcomes, and aligning decisions with core values and customer outcomes for incremental growth.  Mike also reveals insights from his experience working with Bob Moesta on jobs-to-be-done interviews, highlighting the value of going deep in customer research to uncover valuable insights, and in his case, understand attendees' needs and improve the conference and/or community experience.  Takeaways include asking deeper questions, spending more time gathering that qualitative feedback so that you can go deeper, being curiously observant of jobs-to-be-done, and finding various modalities in which to gather continuous feedback from the “friendlies” and those who are more hesitant to capture a complete picture.  Resources Follow Mike Belsito on LinkedIn Explore the free resources and upcoming events at mindtheproduct.com Listen to Mike on Rocketship.fm Follow Holly on LinkedIn Visit the Product Science Group website Explore Product Science Workshops and Courses  Quotes from Mike Belsito (00:06:52) "The job that people hire your product for, you know, if you want to think of it, in jobs to be done context, it may not be what you think it is." - Mike Belsito (00:21:29) "Qualitative data is data. So being data driven doesn't mean that we're relying only on the reports and the analytics. It's not an either or. It's not quantitative versus qualitative. It's using them both together." - Mike Belsito (00:28:15) "It's not just what you've learned, but it's these relationships that are a real value to you." - Mike Belsito Lab Notes Lab Note 607.1: Depth is where you find Differentiation. Lab Note 607.2: Start with observation of the jobs-to-be-done. Lab Note 607.3: Use different modalities to get feedback from a range of people. 

Hypothesis 2  

From apostolic succession to secret ballots, the history of papal elections is rich and fascinating. We explore how popes have been chosen across the centuries, and also tackle questions on sanctuary use, offensive Talmudic texts, and disposing of a damaged rosary. Join The CA Live Club Newsletter: Click Here Invite our apologists to speak at your parish! Visit Catholicanswersspeakers.com Questions Covered: 07:43 – I am a Catholic school teacher and they use the sanctuary for plays immediately after mass. What are the rules for use of the sanctuary?  14:44 – I see a lot of bumper stickers at church of an M with a line through it. Does that have any significance? How does one dispose of a damaged rosary?  18: 58 -Can you give a brief history of how popes were elected?  29:14 – In the Talmud it says that Jesus is burning in hell. What do I make of this?  40:41 – Jn 11 and Jn 12 there’s a plot to kill Lazarus after being raised from the dead. Did they ever succeed in their plot?  43:13 – Can you bless non-Catholic items like a buddha?  48:14 – Are you familiar with the documentary, Hypothesis? When do they go from using the name YHWH to Elohim? 

In the concrete jungle of modern urban living, we've lost something fundamental: our connection to the natural world. But Biophilic Design is offering a lifeline, promising to transform our cities from sterile, energy-hungry environments into vibrant, living ecosystems that nurture both human health and planetary well-being.We speak with Luke Engleback, who has over 40 years' experience as a designer at all scales. We talk about biophilic design, ecourbanism, biodiversity, climate change adaptation and health. Luke is a board member and former chair of the Landscape Foundation. He also sits on the Landscape Institute Policy and Public Affairs Committee, and the Midlands Design Panel, the Cambridge Quality Panel and the South Downs National Park. For Luke Biophilic Design isn't just another architectural trend. It's a radical reimagining of how we live, work, and interact with our surroundings. At its heart lies a simple yet profound understanding: we are not separate from nature, but intrinsically part of it.Recent groundbreaking research provides compelling evidence of nature's transformative power. In Finland, a remarkable study revealed the profound impact of natural environments on children's health. Two daycare centres became an unexpected laboratory of discovery. One centre introduced forest soil and leaf litter into its play area, allowing children to get delightfully messy. The results were astonishing. Children in this natural setting developed more diverse microbiomes and, crucially, had fewer harmful pathogens compared to their peers in clinically clean environments.Similar research in Barcelona uncovered another revelation. Medical researchers discovered that children raised in greener urban spaces demonstrated significantly better cognitive performance. This wasn't about wealth or privilege, but about the fundamental human need to connect with living systems.These aren't isolated examples, but part of a growing understanding that our built environments dramatically impact our physical and mental well-being. Climate change has accelerated this recognition. Cities are becoming unbearable heat islands, with temperatures rising dramatically. But biophilic design offers a sophisticated, multi-layered solution. Eco-urbanism emerges as the critical framework for this transformative approach. It's not just design, but a holistic systems thinking methodology that challenges traditional urban planning. Where conventional approaches work in rigid, isolated silos – treating transportation, water management, energy, and green spaces as separate challenges – eco-urbanism sees the city as a living, interconnected organism.Luke Engelback describes this approach as "elastic thinking" – the ability to zoom in and out, understanding how individual interventions connect to broader ecological systems. It's about breaking down artificial boundaries between disciplines, recognizing that a rain garden isn't just about managing water, but about hydrating urban soils, supporting biodiversity, sequestering carbon, and creating cooling microclimates.This systems approach means reimagining every urban element. A street becomes more than a transportation corridor – it's a potential site for water management, carbon capture, biodiversity support, and community well-being. A building's facade isn't just a structural element, but an opportunity for vertical gardens, air purification, and thermal regulation.Innovative urban planners are reimagining cityscapes as living, breathing entities. In Florence, architects designed a revolutionary urban cooling system using natural wind patterns, channelling sea breezes over water features to reduce the need for energy-intensive air conditioning. In the UK, a visionary project Luke worked on in Ashford proposed transforming large agricultural fields into interconnected woodland patches, simultaneously addressing flooding risks, carbon sequestration, and landscape restoration.But biophilic design isn't just about grand architectural gestures. It's accessible to everyone. As landscape architect Luke passionately argues, even small actions matter. A pot plant on a windowsill, a patch of wildflowers instead of a concrete driveway – these seemingly minor interventions create a cumulative positive impact.The potential is extraordinary. Imagine cities where every surface becomes an opportunity for life – green roofs, living walls, urban forests, and integrated water management systems. Where buildings don't just shelter us but actively contribute to ecological regeneration.This isn't wishful thinking. Luke reminds us that leading scientists like Edward O. Wilson have long advocated for a radical reimagining of our relationship with the natural world. His vision of dedicating half the Earth to nature isn't about creating vast, untouchable reserves, but about understanding our fundamental interdependence.Biophilic design represents a paradigm shift from the destructive, linear "take-make-waste" economic model to a circular, regenerative approach. It challenges the siloed thinking that has dominated urban planning, replacing it with systems thinking that recognizes the intricate connections between human health, ecological systems, and urban infrastructure.Luke also says that the benefits extend far beyond environmental sustainability. Research consistently shows that exposure to natural environments reduces stress, improves cognitive function, and supports overall well-being. This is true, in an age of increasing mental health challenges, this isn't just design – it's a form of collective therapy.As our cities continue to grow and climate change intensifies, biophilic design isn't a luxury. It's a necessity. It offers a hopeful, practical pathway to creating urban environments that don't just sustain us but help us thrive.The revolution starts small, as Luke suggests, even a plant on a windowsill, a community garden, a green roof. But its potential is limitless. We are at the pivot point to the future of urban living, where every design choice is an opportunity to reconnect, regenerate, and reimagine our relationship with the living world. Luke has written a brilliant article in our Journal “Biophilic Design and Ecourbanism – an example at Cannock Mill Co-housing, Colchester Winner of the 2024 SALUS Healthy City Design Award for Healthy homes & neighbourhoods”, The Journal of Biophilic Design, Issue 14, Third Age, pp. 82 -87www.studioengleback.com If you like this, please subscribe!Have you got a copy of the Journal? You can now subscribe to the digital edition or purchase a copy directly from us at the journalofbiophilicdesign.com or Amazon. If you like our podcast and would like to support us in some way, you can buy us a coffee if you'd like to, thank you xWatch the Biophilic Design Conference on demand herewww.biophilicdesignconference.comCredits: with thanks to George Harvey Audio Production for the calming biophilic soundscape that backs all our podcasts. Did you know our podcast is also on Audible, Amazon Music, Spotify, iTunes, YouTube, Stitcher, vurbl, podbay, podtail, and most if not all the RSS feeds?Facebook https://www.facebook.com/journalofbiophilicdesign/Twitter https://twitter.com/JofBiophilicDsnLinkedIn. https://www.linkedin.com/company/journalofbiophilicdesign/Instagram https://www.instagram.com/journalofbiophilicdesign

The Path of Souls in Native American Mound Cultures and the Missihuasca Hypothesis with P. D. Newman P. D. “Danny” Newman is author of Alchemically Stoned: The Psychedelic Secret of Freemasonry, Angels in Vermilion: The Philosopher's Stone from Dee to DMT, and Theurgy: Theory and Practice – The Mysteries of the Ascent to the Divine. … Continue reading "The Path of Souls in Native American Mound Cultures and the Missihuasca Hypothesis with P. D. Newman"

Kyle discusses the history and proof for the small world hypothesis.

In today's war diary, Nikolai Feldman and Alexey Arestovich discussed the main news on the 1146th day of war:➤ 00:00 Tragedy in Sumy: formal logic of the Russian strike in terms of damage to the Ukrainian Armed Forces.➤ 04:05 Questions about the tragedy in Sumy to the Ukrainian leadership. A war crime by Russians and the careless negligence of Ukrainians.➤ 08:08 Sumy: Ukrainian servicemen were not hit, but civilians were killed.➤ 11:11 Why does the army exist? - The military exists so that civilians do not die.➤ 12:10 Conclusions from the tragedy and the responsibility of the military.➤ 14:44 Peace track and agreements reached for the current period. Zelensky's CBS interview laced with insults at the Trump administration.➤ 19:20 Hypothesis about the message from Zelensky's interview: I want to continue the war and I don't care how many civilians die.➤ 20:32 Trump's reaction to the actions of the Russians and Zelensky's speech. Problematized status of US as a mediator.➤ 22:46 What signal are the Russians transmitting, disregarding the civilian losses at war? Putin provided the Russian military with a favorable regime for striking Ukraine. The enemy is the best teacher. Our own position is the problem.➤ 35:46 The essence of the narrow Ukrainian project and signals from the central government. The war is a consequence of Ukraine's main problem - the Narrow Nationalist Project. The challenge for Ukrainians is to recognize, acknowledge and change the track.➤ 41:35 Zelensky's high ratings and support from Ukrainians after the scandal in the Oval Office: Zelensky now demands the right to be re-elected. What can Ukrainians do?➤ 45:53 Examples of madness.Olexiy Arestovych (Kiev): Advisor to the Office of Ukraine President : https://en.wikipedia.org/wiki/Oleksiy_ArestovychOfficial channel: https://www.youtube.com/channel/UCjWy2g76QZf7QLEwx4cB46gNikolay Feldman - Ukranian journalist, social researcher, blogger.

Read this Question of the Week Here: https://www.reasonablefaith.org/writings/question-answer/tegmarks-mathematical-universe-hypothesis-and-natural-theology

This is Part I of our Deep Learning Series where Le Random's editor-in-chief Peter Bauman (Monk Antony) speaks with the most relevant figures in deep learning art. In this first installment, Peter speaks with two of the earliest artists to engage with the intersection of art and deep generative models, Tom White (dribnet) and Gene Kogan.They explore the artistic, philosophical and cultural implications of GANs and deep generative models, drawing on the artists' early experiences and perspectives in the field . The conversation touches on the origins of their interest in GANs, the evolution of AI and its perception, critiques of AI art, the nature of machine representations, and the connection between AI and decentralization.Chapters

UFO #Nephilim #Orbs #Disclosure #BreakawayCivilizationUnsealed: The Full Hypothesis. All 4 parts combined into one. A master theory about the UFO phenomenon, Nephilim, Tower of Babel, Orbs, government cover-ups, super advanced humans in another realm, the Moon and more. This Christian is preparing as if the "benevolent space brothers" and "DEMONS!" options are both wrong. Think we are onto something? Become a member on YouTube, Patreon or X, or just to be nice at wingsoftheeagle.com/supportunsealed

In this episode, host Ethan Nash discusses the four categories of feedback: feedback on ideas, on performance, on skills and competencies, and on style. A functioning team, he explains, is comfortable giving and receiving all types of feedback.  Ethan wraps up the episode with some discussion questions for managers to gauge their teams' comfortability with feedback, with the goal of creating a culture of feedback at work.  We mentioned episode 96, "Coaching by Hypothesis" in this episode.  Text the word “LEADING” to 66866 to be added to Nash Consulting's monthly newsletter. Just practical management skills and tips. And just once a month. Pinky swear.

Tim explains AI co-scientist, a tool released by Google, which it hopes to help scientists generate hypotheses and research proposals, and to accelerate the speed of scientific and biomedical discoveries. Hosts: Vincent Racaniello, Tim Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server AI cracks superbug problem (BBC) Accelerating scientific breakthroughs (Google Research) Towards an AI co-scientist (arXiv) Timestamps by Jolene Ramsey. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv

Ha Nguyen, a seasoned Silicon Valley product leader, then co-founding partner at Spero Ventures, Chief Experiences Officer at Swimply, and now Managing Partner at NextStep, a fractional & advisory COO consulting firm, shares her perspective, lessons learned, and journey through the ranks with us today.  Ha's journey underscores the importance of adaptability, continuous learning, and leveraging networks in navigating a product management career. She highlights the significance of being proactive, driving outcomes, and having the courage to ask for opportunities and support from leadership. Ha's experience showcases how excelling in one's function, seeking opportunities for growth and expansion, and being ready to pivot when necessary can lead to transformative career shifts, such as her transition from a VP of Product role to venture capital. Continuous product discovery is proven critical through Ha's story, even as companies scale, emphasizing the need to maintain customer contact and understanding throughout growth phases. Ha Nguyen's advice on driving impact, seeking expanded responsibilities, and being willing to walk away when opportunities for growth are limited resonates with the team at Product Science Group. By prioritizing personal growth, seeking supportive environments, and proactively shaping their career paths, product developers and leaders can make strategic decisions that propel their careers and products forward. Resource Links: Follow Ha Nguyen on LinkedIn Visit NextStepFwd, Ha's Consulting website Join the NextStep Substack Follow Holly on LinkedIn Visit the Product Science Group website Explore Product Science Workshops and Courses Quotes from Ha Nguyen: (00:05:45) "I felt like I was ready to sort of increase my scope and my impact, albeit at a smaller company. However, I really wanted to have more influence over the direction of the company, not just the direction of our products." - Ha Nguyen (00:09:39) "Be incredibly good at what you do. Startups give you the opportunity to have expanded scope, work for a great boss who's supportive of your career. Don't be afraid to ask. And then finally, if. If they're not going to support you and what you need, then you might need to make the decision to walk." - Ha Nguyen (00:28:47) "When you build the network and people have seen that you have been putting the hours in to build what I call the labor of love projects, it, it's just easier because when you need to reach out to folks for anything they want to help you, they'll pick up the phone and they'll help you." - Ha Nguyen Lab Notes:  Lab Note 605.1: As a company grows, you must intentionally create structure for continuous product discovery. (00:31:46) Lab Note 605.2: Raise your hand to access new opportunities. (00:33:03) Lab Note 605.3: There are varied perspectives on work-life balance and startup life. (00:34:07) Lab Note 605.4: Fractional product work is a great fit for creative people who thrive in ambiguity, but it's not accessible or right for everyone. (00:36:38) Lab Note 605.5: Invest in your network throughout your career and it will pay dividends. (00:40:27) View the transcript and the ⁠full episode description on the Product Science Podcast website here.⁠

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Jon Hartley and Eugene Fama discuss Gene's career at the University of Chicago Booth School of Business since the 1960s and helping to start Dimensional Fund Advisers (DFA) in the 1980s, fat tails, the rise of modern portfolio theory, efficient markets versus behavioral finance, factor-based investing, the role of intermediaries, and whether asset prices are elastic versus inelastic with respect to demand. Recorded on March 14, 2025. ABOUT THE SPEAKERS: Eugene F. Fama, 2013 Nobel laureate in economic sciences, is widely recognized as the "father of modern finance." His research is well-known in both the academic and investment communities. He is strongly identified with research on markets, particularly the efficient markets hypothesis. He focuses much of his research on the relation between risk and expected return and its implications for portfolio management. His work has transformed the way finance is viewed and conducted. Fama is a prolific author, having written two books and published more than 100 articles in academic journals. He is among the most cited researchers in economics. In addition to the Nobel Prize in Economic Sciences, Fama was the first elected fellow of the American Finance Association in 2001. He is also a fellow of the Econometric Society and the American Academy of Arts and Sciences. He was the first recipient of three major prizes in finance: the Deutsche Bank Prize in Financial Economics (2005), the Morgan Stanley American Finance Association Award for Excellence in Finance (2007), and the Onassis Prize in Finance (2009). Other awards include the 1982 Chaire Francqui (Belgian National Science Prize), the 2006 Nicholas Molodovsky Award from the CFA Institute recognizing his work in portfolio theory and asset pricing, and the 2007 Fred Arditti Innovation Award given by the Chicago Mercantile Exchange Center for Innovation. He was awarded doctor of law degrees by the University of Rochester and DePaul University, a doctor honoris causa by the Catholic University of Leuven, Belgium, and a doctor of science honoris causa by Tufts University. Fama earned a bachelor's degree from Tufts University in 1960, followed by an MBA and PhD from the University of Chicago Graduate School of Business (now the Booth School) in 1964. He joined the GSB faculty in 1963. Fama is a father of four and a grandfather of ten. He is an avid golfer, an opera buff, and a former windsurfer and tennis player. He is a member of Malden Catholic High School's athletic hall of fame. Jon Hartley is currently a Policy Fellow at the Hoover Institution, an economics PhD Candidate at Stanford University, a Senior Fellow at the Foundation for Research on Equal Opportunity (FREOPP), a Senior Fellow at the Macdonald-Laurier Institute, and an Affiliated Scholar at the Mercatus Center. Jon also is the host of the Capitalism and Freedom in the 21st Century Podcast, an official podcast of the Hoover Institution, a member of the Canadian Group of Economists, and the chair of the Economic Club of Miami. Jon has previously worked at Goldman Sachs Asset Management as a Fixed Income Portfolio Construction and Risk Management Associate and as a Quantitative Investment Strategies Client Portfolio Management Senior Analyst and in various policy/governmental roles at the World Bank, IMF, Committee on Capital Markets Regulation, U.S. Congress Joint Economic Committee, the Federal Reserve Bank of New York, the Federal Reserve Bank of Chicago, and the Bank of Canada.  Jon has also been a regular economics contributor for National Review Online, Forbes and The Huffington Post and has contributed to The Wall Street Journal, The New York Times, USA Today, Globe and Mail, National Post, and Toronto Star among other outlets. Jon has also appeared on CNBC, Fox Business, Fox News, Bloomberg, and NBC and was named to the 2017 Forbes 30 Under 30 Law & Policy list, the 2017 Wharton 40 Under 40 list and was previously a World Economic Forum Global Shaper. ABOUT THE SERIES: Each episode of Capitalism and Freedom in the 21st Century, a video podcast series and the official podcast of the Hoover Economic Policy Working Group, focuses on getting into the weeds of economics, finance, and public policy on important current topics through one-on-one interviews. Host Jon Hartley asks guests about their main ideas and contributions to academic research and policy. The podcast is titled after Milton Friedman‘s famous 1962 bestselling book Capitalism and Freedom, which after 60 years, remains prescient from its focus on various topics which are now at the forefront of economic debates, such as monetary policy and inflation, fiscal policy, occupational licensing, education vouchers, income share agreements, the distribution of income, and negative income taxes, among many other topics. For more information, visit: capitalismandfreedom.substack.com/

How do CPOs balance keep teams engaged in meaningful work while building a product strategy from scratch? Stephanie Leue, Chief Product Officer at Doodle at the time of this recording, shares how she integrates customer feedback, collaboration with internal teams, and data-driven insights to inform strategic decisions, underscoring the value of communication and using various artifacts to convey the product strategy effectively across the organization. By engaging in discovery while leveraging foundational work, teams can build trust and demonstrate progress to stakeholders. Stephanie's experience as a seasoned product leader in B2B SaaS, along with her focus on leadership coaching and diversity and inclusion, underscores the critical role of experienced product leaders in making the craft of product management appear seamless.  Overall, her approach emphasizes the iterative nature of product strategy development, de-risking bets with data and discovery, and fostering collaboration and trust within teams to drive meaningful progress and innovation in product development. Resource Links Visit Stephanie's webpage Follow Stephanie Leue's Substack Follow Stephanie Leue on LinkedIn Visit the Doodle website Follow Holly on LinkedIn Visit the Product Science Group website Explore Product Science Workshops and Courses Quotes from Stephanie Leue:"We just don't want to build one feature after another. We want to have kind of a bigger picture in mind and we want to achieve that bigger version of what we are today, right?" “If you show them 1 minute 20 about the future of a product, they immediately have 20,000 things that will never work out. And they have 20,000 questions and like tons of ideas why things will take way longer than expected. But to be honest, that's exactly the discussion you want to have, right?”  “We needed to train ourselves to ask the right questions. We needed to get answers to these questions. We needed to understand the data we got. We needed to compose a picture out of that data. So that takes a while because that's like a team effort.” Lab Notes Lab Note 604.1: Experienced product leaders make the craft of product management look easy Lab Note 604.2: Strategy is a series of bets that can make even the CPO uncomfortable Lab Note 604.3: Use different communication approaches for different audiences of your product strategyLab Note 604.4: Find foundational alignment and begin executing while you are developing your bigger product strategy Ready to elevate your product leadership game? Dive deep into practical solutions for real-world product challenges. Register now: https://www.productsciencegroup.com/services View the transcript and the ⁠full episode description on the Product Science Podcast website here.⁠

Is depression really caused by low serotonin? Dr. Awais Aftab joins Dr. David Puder to explore the serotonin hypothesis, antidepressant efficacy, and the controversies surrounding SSRIs. They dive into the history of the serotonin deficiency theory, key research on antidepressants vs. placebo, and how neuroplasticity, psychotherapy, and lifestyle changes factor into depression treatment. The episode also examines differences between major treatment guidelines, including RANZCP and NICE, and what the latest evidence suggests about the future of mental health care. By listening to this episode, you can earn 1.25 Psychiatry CME Credits. Link to blog. Link to YouTube video. Links for Dr. Awais Aftab: Substack World Psychiatry Conversations in Critical Psychiatry

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