Lessons from Lab and Life

Dr. Carolyn Bertozzi's impact in the field of glycosylation has been profound, enabling on our current understanding of disease and inflammation presentation and potential vehicles for treatment. Dr. Bertozzi was awarded the Nobel Prize in 2024 for the development of biorthogonal chemistry, and she explains how this understanding can impact disease treatment. 

NEB technical support scientist, Jack Martz and NEB Development Scientist Heejin Kim talk about best practice for DNA Cleanup. We will talk about the history of DNA Cleanup and the methods available, as well as share some guidance on selecting the method that is right for your work.

In this podcast, Dr. Anne Madden, founder of the Microbe Institute, shares why understanding microbes is important and why she is compelled to educate others.

Dr. Rita Colwell, internationally recognized expert on cholera and other infectious diseases, shares insights from a lifetime in the field of science.

Dr. Ben Kleinstiver, whose lab is located at the Center for Genomic Medicine at Mass General Hospital, joins us to talk about programmable nucleases, genome editing, and the applications of this technology in the future of healthcare.

The three Passion in Science Award winners in the Category of Arts and Creativity joined us in the studio to talk about their art and what initiated its creation. Sam Siljee shares his soundscapes, Sally Kong describes her weaving patterns, and Michael Weiner his details his uniquely scientific large-scale portraits.

In this podcast, New England Biolabs Associate Director of Research, Nathan Tanner explains the portfolio of NEB products called Enzymes for Innovation.

In this podcast, Sophie Vaud explains the environmentally friendly textile dyeing process developed by Colorifix.

In this podcast, Dr. James Lee discusses his research efforts to identify biomarkers and molecular disease-drivers of inflammatory bowel disease.

In this podcast, Claudia Gonzaga-Jauregui explains how she is working to increase access to molecular diagnostics and precision medicine in Mexico and Latin America.

2014 Passion in Science Award winner Shelly Xie joins us to share what she has learned about the benefits of art for healthcare providers and patients. 

NEB Production Scientist Lindsey Spiegelman, joins us to explain the seamless DNA assembly method NEBuilder, which was developed at NEB. NEBuilder HiFi offers fast, accurate assembly of DNA fragments, including the ability to easily assemble DNA libraries, as well as the ability perform multisite mutagenesis in a single reaction.

Dr. Jo Handelsman, Director of the Wisconsin Institute for Discovery shares her expertise in microbiome research and the importance of community. 

The Genes in Space team joins NEB to share the mission of their program, and 2023 Genes in Space Contest winner Isabel Jiang explains how her experience with the program has impacted her education, and the details of her experiment – which will be performed aboard the International Space Station.

NEB Emeritus Scientist Bill Jack explains how the discovery of new enzymes has helped advance the capabilities and possibilities of molecular cloning

Hear NEB Research Scientist Andy Sikkema, introduce Golden Gate Assembly and it's uses, as well as tips for successful DNA assemblies.

Hear NEB Senior Tech Support Scientist Rachel Carver-Brown explain site-directed mutagenesis and multi-site mutagenesis techniques.

Hear from Genes in Space 2022 contest winner Pristine Onuoha, whose experiment explores the measurement of DNA length in space.

Hear Dr. Sesay explain how The Gambia dealt with the COVID-19 pandemic and how it has influenced the country's preparedness for future viral outbreaks.

Hear NEB Development Group Leader Brad Langhorst talk about how bioinformatics informs sequencing, from primer design to analysis.

Hear Charlotte Houldcroft, lecturer at the University of Cambridge – talk sequencing, from double-stranded DNA viruses to ancient DNA.

Hear Mihir Kekre, who spent 4 years at the Centre for Genomic Pathogen Surveillance at the Wellcome Sanger Institute, share his experience in antimicrobial resistance research and pathogen surveillance.                                  

Hear Chip Taylor, founder of the non-profit Monarch Watch, share his research findings and explain how we can help protect this endangered insect.

Hear MIT Lecturer Jessie Stickgold-Sarah, who shares her perspective on the importance of good communication skills –– especially in science.

Hear Susan Aitken, Molecular Laboratory Asst. Manager of the HUCL lab, which provided testing for Harvard and MIT students and staff during the pandemic.

Hear Dr. Anu Rebbapragada of FH Health – a Health-Tech company that was created early in the COVID-19 pandemic to address public diagnostic testing needs.

Hear Dr. Nídia Trovão of the Fogarty International Center at the NIH, explain how the evolution of viral pathogens in human and animal populations are studied and the insights this research offers. 

Hear how the nonprofit organization Reforest the Tropics is working to capture carbon through reforestation from the company's Executive Director Greg Powell.

Hear from Dr. Bijoyita Roy, NEB RNA Research Senior Scientist, whose work focuses on mRNA synthesis, methods for RNA research and RNA therapeutics.

An interview with Dr. Eileen Dimalanta, Associate Director of Applications and Product Development at NEB, whose work focuses on next generation sequencing. 

Hear from Dr. Tilde Carlow, Scientific Director of Genome Biology at NEB, who has dedicated her career to infectious disease research.

Hear from Dr. Neville Sanjana about his publication detailing the use of modified guide RNAs and protein delivery to enhance control of CRISPR/Cas13 activity.

Hear from Professor Jim Collins of MIT how synthetic biology helped us detect and mitigate the COVID-19 pandemic and how it can help prevent future pandemics.

Hear from Professor Karmella Haynes, whose work focuses on using synthetic biology to fine tune approaches to epigenetic medicine. 

Hear from Tom Ellis, Professor of Synthetic Genome Engineering, in the Department of Bioengineering at Imperial College London whose lab focuses on using synthetic biology to enable scalable production of Engineered Living Materials.

Hear from Professor Jim Haseloff, whose work has primarily focused on using synthetic biology to engineer plant growth, but during the pandemic he has focused his efforts on increasing global accessibility of low-cost instrumentation and access to diagnostics.

Hear Kate Creasey Krainer explain how the Grow More Foundation is bringing synthetic biology tools to developing countries to help end world hunger.

Listen as Claudia Vickers of CSIRO explains both her work engineering plant pathways within microbes to manufacture natural products and how Australia is focusing building synthetic biology.

Hear Todd Camenisch describe the COVID-19 surveillance testing program that he helped establish, which is guiding precaution and mitigation efforts at St. John Fisher College.

Hear vaccine expert Dr. Peter Hotez discuss his new book, his thoughts on the current COVID-19 pandemic, vaccine development and manufacturing, as well as democratizing vaccine distribution.

Hear Bas Oude Munnink of Erasmus MC in the Netherlands about the ongoing sequencing of SARS-CoV-2 in the country and what it has revealed.       

Hear scientists from the Chan Zuckerberg Biohub and UCSF describe their work providing COVID-19 testing and genomic sequencing of SARS-CoV-2 for California.

Hear Joshua Quick explain how the ARTIC Network's protocol for sequencing SARS-CoV-2 is helping the world better understand the virus and its global spread.

Hear Naama Geva-Zatorsky explain how her lab is using LAMP technology to detect SARS-CoV-2 directly from saliva or UTM containing swab samples.

Hear from Feng Zhang, Omar Abudayyeh and Jonathan Gootenberg about the STOPCovid initiative for point-of-care testing for COVID-19.

Hear from Brian Rabe of HMS about his work applying RT-LAMP to develop a fast SARS-CoV-2 diagnostic assay.

Hear from James Bevington about how he is applying synthetic biology to space studies and the potential of life on Mars.

Hear how to move your laboratory toward zero waste from experts in lab sustainability and recycling, lab plastic manufacturing and microplastics pollution.

Listen to members of the Genes in Space program as they talk about the program's mission and its impact on young scientists.

Listen to Dr. Eva Nogales describe how cryo-electron microscopy addresses the challenge of visualizing macromolecular structures.

Hear from NEB Scientists Mehmet Berkman and Paul Riggs about the lessons that New England Biolabs has learned about protein expression and purification over the last 40 years.