Podcasts about microbial

True health encompasses so much more than just diet and exercise. However, you don't need complicated routines, a lot of money, or elaborate gadgets to make a positive impact on your health. Some of the most powerful things you can do to improve your longevity, boost your immune system, and lower your stress have to do with simple behaviors and habits you can create in your home. Today, you're going to learn about the impactful role that community can have on your microbiome, your disease risk, and your overall health. On this episode of The Model Health Show, you're going to hear my conversation with the incredible Dr. Amy Shah for her podcast, Save Yourself. In this conversation, we discussed the importance of shared family meals, how to prioritize eating real food, and why your relationships are a key determinant of your health. This episode is packed with the science behind how cultivating healthy relationships can influence your microbiome, your sleep, your immune system, and so much more. You're also going to learn the top two most important things you can do to transform your health. I hope you enjoy my conversation with Dr. Amy Shah!  In this episode you'll discover:  The most important part about being human. (09:48) How eating with your family can impact your health. (12:22) Why being part of a community can improve your microbiome. (14:47) The health benefits of multi-generational living. (17:52) An interesting fact about humans, evolution, and menopause. (23:13) Why creating your own community can transform your life. (25:24) How sharing meals with your children can reduce their risk of obesity and disordered eating. (28:04) The connection between the time spent at a table and health outcomes. (33:45) What the #1 factor is that influences longevity is. (38:04) Which hormone is the antidote to stress. (39:27) Why personalization is the key to health. (41:22) The most powerful nutrition shift you can make. (41:44) How American children's diets have become inundated with ultra-processed food. (42:37) The #1 way to minimize the ultra-processed food in your diet. (45:50) What post-ingestive feedback is. (49:14) What sleep nutrients are. (54:41) How often you should aim to share a meal with others. (58:09)  Items mentioned in this episode include:  Beekeepersnaturals.com/model - Save 25% sitewide through May 27!  PaleoValley.com/model - Use code MODEL for 15% off! Save Yourself with Dr. Amy Shah - Subscribe to Dr. Amy Shah's podcast! Eat Smarter Family Cookbook - Transform the health, fitness, and connection of your entire family with the Eat Smarter Family Cookbook!  Be sure you are subscribed to this podcast to automatically receive your episodes:   Apple Podcasts Spotify Soundcloud Pandora YouTube   This episode of The Model Health Show is brought to you by Beekeeper's Naturals and Paleovalley. Reinvent your medicine cabinet for with clean, effective products powered by the beehive & backed by science. Shop the Memorial Day Sale now through May 27th and get 25% off sitewide at beekeepersnaturals.com/model. Use my code MODEL at PaleoValley.com/model to save 15% sitewide on nutrient dense snacks, superfood supplements, and more.   

Microbial forensics is a science that lets us trace killers and terrorists by the microscopic footprints they leave behind. From the landmark 1994 HIV murder case where viral genetics first convicted a doctor, to the chilling Amerithrax investigation after 9/11. You'll learn how microbes are rewriting crime solving while we explore true cases, cutting-edge research on skin microbiomes and microbial death clocks, and what the future holds when invisible evidence becomes undeniable.   TOPICS DISCUSSED IN THIS EPISODE: What skin microbiomes reveal about who touched what and when How microbes can be used to map the timeline of a crime scene Intelligence agencies using "microbial geolocation" to trace where you've been How microbial forensics was used to solve a murder and trace the post 9/11 Anthrax murders The future of turning invisible bacterial clues into courtroom evidence Why microbial forensics could reshape how we solve crime—and even prevent terrorism   Leave us a Review: https://www.reversablepod.com/review   Need help with your gut? Visit my website gutsolution.ca to join a program: Get help now   Contact us: reversablepod.com/tips    FIND ME ON SOCIAL MEDIA: Instagram  Facebook  YouTube        

Matters Microbial #91: You Are What Your Genes Feed Your Microbiome May 16, 2025 Today, Dr. Emily Davenport, Assistant Professor in the Department of Biology and Huck Institutes of the Life Sciences at Penn State University, joins the #QualityQuorum to tell us about the research her team does, studying how our own genes impact our microbiomes.   Host: Mark O. Martin Guest: Emily Davenport Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A description of GWAS (“Genome Wide Association Study”).  Here is an introductory video about the concept. An explainer on organoids. An essay about the diversity of the host microbiome (i.e. is there a “healthy” microbiome?). An article of the work of Dr. Sarkis Mazamian on how individual host genes and bacterial genes can impact the microbiome. A nice write up for Dr. Mazamian's work showing how host genes and bacterial genes can work together…or not. An oldish video of how the infant microbiome develops over time by Dr. Rob Knight's research group. An article on the same topic from Dr. Ruth Ley. An essay on the mucosal microbiota, rather than the fecal microbiome. An interesting member of the human microbiome, Akkermansia that might be related to obesity. Another interesting member of the human microbiome, Bifidobacterium, which appears to be associated with host lactose metabolism.  Yes, there is a Giant Microbes plush toy. An overview of the impact of host genetics on the microbiome by Dr. Davenport.  A definition of heritability. An overview of the Hutterites and how their study has advanced genetics. An explainer of the power of twin studies in genetics. A fascinating article about ancient dental plaque microbiome by Dr. Davenport and others. Dr. Davenport's faculty website. Dr. Davenport's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

This Podcast Extra episode is from John's Ask Me Anything webinar from April 14. Drawing from his extensive research and firsthand experience, John will provide insights and practical solutions to help growers achieve healthier, more resilient crops. In this discussion, the topics cover: Nutritional management with copper, nitrogen, potassium, and calcium prevents wheat and barley lodging better than PGRs.  Soil aeration and oxygen flow enhance paramagnetism more effectively than paramagnetic rock powders. Side-dressing potassium, like potassium nitrate, benefits soil biology more than broadcasting potash. Adequate calcium and boron levels, plus soil aeration, reduce clubroot in brassicas. Compost, low soil carbon, and lack of humic substances cause high chloride in plant sap, mitigated by humicarb. Selenium may influence fatty acid profiles and yield in forages, but its role in oil crops is unclear. Balancing potassium and calcium with manganese and boron ensures optimal plant health. Microbial activity and preventing soil drying enhance potassium availability in clay soils. Micropack offers higher performance than seaweed or fish-based foliar sprays for tropical fruit groves. Deeper earthworm presence reflects better soil aeration and structure, not necessarily overall soil health. Seed Flare may penetrate sunflower shells but is less effective on stone fruit, needing experimentation. BioCoat Gold is best as a seed treatment but can be applied in-furrow.  About John Kempf John Kempf is the founder of Advancing Eco Agriculture (AEA). A top expert in biological and regenerative farming, John founded AEA in 2006 to help fellow farmers by providing the education, tools, and strategies that will have a global effect on the food supply and those who grow it. Through intense study and the knowledge gleaned from many industry leaders, John is building a comprehensive systems-based approach to plant nutrition – a system solidly based on the sciences of plant physiology, mineral nutrition, and soil microbiology. Support For This Show & Helping You Grow Since 2006, AEA has been on a mission to help growers become more resilient, efficient, and profitable with regenerative agriculture.  AEA works directly with growers to apply its unique line of liquid mineral crop nutrition products and biological inoculants. Informed by cutting-edge plant and soil data-gathering techniques, AEA's science-based programs empower farm operations to meet the crop quality markers that matter the most. AEA has created real and lasting change on millions of acres with its products and data-driven services by working hand-in-hand with growers to produce healthier soil, stronger crops, and higher profits. Beyond working on the ground with growers, AEA leads in regenerative agriculture media and education, producing and distributing the popular and highly-regarded Regenerative Agriculture Podcast, inspiring webinars, and other educational content that serve as go-to resources for growers worldwide. Learn more about AEA's regenerative programs and products: https://www.advancingecoag.com

Matters Microbial #90: Using Soil Microbiomes in Sustainable Agriculture May 8, 2025 Today, Dr. Francisco Dini Andreote, Assistant Professor of Phytobiomes at Penn State, joins the #QualityQuorum to tell us about the microbiome of plants and the soil, and how understanding that relationship can improve agriculture. Host: Mark O. Martin Guest: Francisco Dini Andreote Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of the Type 6 Secretory System of bacteria—almost like a microbial switchblade knife. A wonderful video of the T6SS made by a student in my own microbiology course some time ago. A video introduction to the Rhizobium-legume symbiosis and why you should care about it (by my PhD advisor from long ago, Dr. Sharon Long). A more comprehensive review article on the Rhizobium-legume symbiosis.  The chemical signal of geosmin, and how it might be used by other organisms. Ecological succession in the development of sauerkraut. A must read essay by Carl Zimmer likening the human body to a number of ecological niches. The developing field of agroecology.  A reminder about the “One Health” concept. Mycorrhizae and plant nutrition. Chemical communication within the soil. A fun remembrance of Norman Borlaug, who urged us to “listen” to plants. An overview of the root microbiome. The “superorganism” concept versus the “holobiome” concept.. Striga, a parasite of crop plants. Chemical communication and Striga.  An interesting and relevant publication from Dr. Dini Andreote's research group, describing how the root microbiome could help agriculture.  Dr. Dini Andreote's faculty website. Dr. Dini Andreote's very wonderful research team website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

We're bringing this powerhouse episode back to your ears—because it's just that good. Microbiologist and gut health innovator Dr. Kiran Krishnan returns for what might be our most impactful conversation yet. Together, we explore why your gut microbiome is the ultimate predictor of resilience, longevity, and even how well you'll respond to illness.Kiran breaks down the staggering impact of microbial diversity, how modern life has wiped out essential strains, and why his team is resurrecting ancient microbes for the modern gut. We also get into what he actually takes when flying 400,000 miles a year, the truth about keto, and how poop (yep!) holds the key to personalized healing.It's science, inspiration, and a whole lot of fun—complete with a poop-testing parody of “Dick in a Box.” You'll walk away with five daily practices to boost gut diversity and a renewed belief in your body's natural brilliance.HIGHLIGHTS[3:42] - How the digital world is changing what we know and how we connect[6:10] - Building resilience vs. chasing perfection in health[8:24] - What centenarians around the world teach us about gut diversity[13:01] - Why your poop holds the answers: shape, frequency, and clues to dysfunction[16:28] - Microbial extinction and why we've lost two-thirds of our gut species[21:56] - What is MegaGenesis and how keystone strains are being brought back[23:54] - Why restrictive diets harm the gut—and what to do instead[28:49] - The new FXBiome test: better resolution, actionable insights[38:24] - Covid, long-haul illness, and the gut's predictive power[43:57] - 5 lifestyle upgrades for gut diversity: from fasting to forest walks[49:32] - Why your household shares microbes—and why dogs help[58:07] - Kiran's closing message: there's always hope when you start with the gutCONNECT WITH DR. KIRAN KRISHNAN + MICROBIOME LABSWebsite: microbiomelabs.comInstagram: @microbiomelabsUPGRADE YOUR WELLNESSBeam Minerals: http://beamminerals.com/beautifullybroken(Use Code: BEAUTIFULLYBROKEN for Discount)Silver Biotics Wound Healing Gel: https://bit.ly/3JnxyDD (30% off)(Use Code: BEAUTIFULLYBROKEN for Discount)StemRegen: https://www.stemregen.co/products/stemregen?_ef_transaction_id=&oid=1&affid=52Code: beautifullybrokenLightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794Code: beautifullybroken CONNECT WITH FREDDIE Check out my website and store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: (https://www.youtube.com/@BeautifullyBrokenWorld)

Matters Microbial #89: Can AI Point Us to New Antibiotics May 1, 2025 Today, Dr. Amir Mitchell, Associate Professor of Systems Biology at the University of Massachusetts Medical School, joins the #QualityQuorum to discuss using artificial intelligence to develop new and effective antibiotics in our endless battle against drug-resistant microbes. Host: Mark O. Martin Guest: Amir MItchell Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An article exploring the impact of the microbiome on drug effectiveness. A blog post discussing the relationship between the gut microbiome and creosote metabolism in wood rats. An essay about the threat of antibiotic resistance. A more scholarly article on this topic. A CDC report of the rise of antibiotic resistance. A very moving TED talk on this topic. An overview of antibiotic resistance mechanisms. A video from Dr. Michael Baym's laboratory demonstrating how rapidly antibiotic resistance can occur. An essay discussing the use of artificial intelligence in the search for new antibiotics.  An article from Dr. Mitchell's research group discussing his approach to identity new antimicrobial compounds. Dr. Mitchell's faculty website. Dr. Mitchell's very interesting research team website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #88: Microbial Interactions in Cystic Fibrosis April 24, 2025 Today, Dr. Reed Stubbendieck, Assistant Professor of Microbiology & Molecular Genetics at Oklahoma State University joins the #QualityQuorum to discuss how microbes and the host communicate with one another in the cystic fibrosis lung. Host: Mark O. Martin Guest: Reed Stubbendieck Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of cystic fibrosis as a disease with a genetic link. A review of the microbiome of the cystic fibrosis lung. An overview of biofilms. An interesting role for extracellular DNA itself as a “building block” of biofilms. An overview of polymicrobial communities. Life in mucus—an interesting essay. An overview of Pseudomonas aeruginosa. Pseudomonas and the siderophore pigment pyoverdin which is not only about iron, but also bacterial conflict and cooperation.   An interesting overview of microbe-microbe interactions, often called “sociomicrobiology,” and an introductory article on this topic. A review of the nasal microbiome. The organism Rothia, understudied and of interest to Dr. Stubbendieck's research group.  Some work from Dr. Stubbendieck's group describing how Rothia is helpful in inhibiting some disease causing bacteria. The organism Dolosigranulum pigrum, also understudied and of interest to Dr. Stubbendieck's research group. More work from Dr. Stubbendieck's group with another possibly probiotic bacterium,  Dolosigranulum pigrum, that may protect against disease causing microbes.  Dr. Stubbendieck's faculty website. Dr. Stubbendieck's very interesting research group website.  Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Dr. Amato is a biological anthropologist studying the influence of gut microbes on host ecology and evolution. Her research examines how changes in the gut microbiota impact host nutrition, energetics, and health. She uses non-human primates as models for studying host-gut microbe interactions in selective environments and for providing comparative insight into the evolution of the human gut microbiota. Her main foci are understanding how the gut microbiome may buffer hosts during periods of nutritional stress and how the gut microbiome programs normal inter-specific differences in host metabolism. In this realm, she is also interested in global variation in the human gut microbiome and its implications for local human adaptation. Dr. Amato obtained her A.B. in Biology from Dartmouth College and her Ph.D. in Ecology, Evolution and Conservation Biology from the University of Illinois at Urbana-Champaign. She completed a postdoc at the University of Colorado Boulder. She joined the Department of Anthropology in 2015. She is also affiliated with the Interdisciplinary Biological Sciences Graduate Program and sits on the Executive Committee of the Northwestern Institute on Complex Systems. Dr. Amato is the President of the Midwest Primate Interest Group, an Associate Editor at Microbiome, an Editorial Board member at Folia Primatologica, and a Fellow for the Canadian Institute of Advanced Research's ‘Humans and the Microbiome' Program. ------------------------------ Find the paper discussed in this episode: Mallott, E., Kuthyar, S., Lee, W., … & Amato, K. R. (2024). The primate gut microbiota contributes to interspecific differences in host metabolism. Microbial genomics, https://doi.org/10.1099/mgen.0.001322 ------------------------------ Contact the Sausage of Science Podcast and Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Chris Lynn, Co-Host. Website: cdlynn.people.ua.edu/, E-mail: cdlynn@ua.edu, Twitter:@Chris_Ly Cristina Gildee, Guest Co-Host, HBA Junior Fellow, SoS producer. Website: cristinagildee.org, E-mail: cgildee@uw.edu, Twitter:@CristinaGildee Anahi Ruderman, SoS Co-Producer, HBA Junior Fellow. E-mail: aniruderman@gmail.com, Twitter: @ani_ruderman

A road trip to a gypsum quarry in Algeria led Youcef Sellam on a journey of scientific discovery. From the road trip to an internship in Italy, he and his colleagues later discovered microbial fossils—marking a first for Algerian gypsum. As a Ph.D. student at the University of Bern, Sellam and his team took this research further. They used a special instrument to detect the chemical signatures of these ancient microbes, demonstrating a method that could one day help search for traces of life on Mars. Their findings, published in Frontiers in Astronomy and Space Sciences, highlight how chemical analysis can reveal biological traces in minerals. Join planetary scientist Beth Johnson and Youcef for a discussion of how this research brings us one step closer to understanding how we might detect past life on the Red Planet. (Recorded live 10 April 2025.)

Do You Want To Improve Your Soil? Are You Fighting Pests? Disease? Drought? Are You Not Seeing the VIGOR You were Hoping For? This Webinar Series is for you. Click the link & Join Us LIVE and you could win one of the giveaways and get a FREE BOOK, T-SHIRT, OR even a COURSE SIGNUP!! Plus we'll have LIVE Q&A for those that attend - Register Here: https://matt-powers.mykajabi.com/soiltransformation Watch this presentation on Youtube here: https://youtu.be/RRAFcdMs6FU

This episode of Space Nuts is brought you with the support of Saily. If you love travelling, you need Saily by your side. To find out more and get the special Space Nuts listener discount, visit www.saily.com/spacenutspace Nuts Episode 513: Microbial Life in Space, Titan's Secrets, and the Search for Intermediate Black HolesIn this engaging episode of Space Nuts, host Heidi Campo returns with astronomer Professor Fred Watson to explore the intriguing intersection of microbiology and space exploration. From the mapping of microbes aboard the Tiangong Space Station to the potential for life beneath the icy crust of Titan, and the latest discoveries about intermediate black holes, this episode is a cosmic journey filled with fascinating insights.Episode Highlights:- Microbial Mapping on Tiangong: Heidi and Fred discuss the China Space Station Habitation Area Microbiome Program (CHAMP) and its efforts to map the microbial life aboard the Tiangong Space Station. They explore the implications of a sterile environment in space and how it might affect astronauts' health upon their return to Earth.- Life on Titan: The conversation shifts to Titan, Saturn's largest moon, where researchers are investigating the possibility of life in its sub-ice ocean. Fred explains how organic nutrients from Titan's surface might migrate through its thick ice layer, and the challenges of sustaining microbial life in such a harsh environment.- Geothermal Activity and Microbial Life: The duo delves into the potential for geothermal activity on Titan and how it might support life. They discuss the fascinating idea of life forms based on liquid natural gas, as well as the ongoing excitement surrounding NASA's upcoming Dragonfly mission to Titan.- Intermediate Mass Black Holes: The episode concludes with a discussion on the search for intermediate mass black holes, particularly in globular clusters. Fred shares insights from recent research that suggests the existence of these elusive black holes, shedding light on their formation and significance in the universe.For more Space Nuts, including our continually updating newsfeed and to listen to all our episodes, visit our website. Follow us on social media at SpaceNutsPod on Facebook, X, YouTube Music Music, Tumblr, Instagram, and TikTok. We love engaging with our community, so be sure to drop us a message or comment on your favorite platform.If you'd like to help support Space Nuts and join our growing family of insiders for commercial-free episodes and more, visit spacenutspodcast.com/aboutStay curious, keep looking up, and join us next time for more stellar insights and cosmic wonders. Until then, clear skies and happy stargazing.(00:00) Welcome to Space Nuts with Heidi Campo and Fred Watson(01:40) Discussion on microbial mapping aboard the Tiangong Space Station(11:20) Exploring the potential for life on Titan(22:15) The implications of geothermal activity in Titan's ocean(30:00) New findings on intermediate mass black holes in globular clustersFor the commercial free versions of Space Nuts join us on Patreon, Supercast, Apple Podcasts or become a supporter here: https://www.spreaker.com/podcast/space-nuts-astronomy-insights-cosmic-discoveries--2631155/support.

Matters Microbial #87: Dietary Protein and the Microbiome April 17, 2025 Today, Dr. Manuel Kleiner, Associate Professor of Microbiomes and Complex Microbial Communities at North Carolina State University,  joins the #QualityQuorum to discuss how diet can influence the microbiome in fascinating ways. Host: Mark O. Martin Guest: Manuel Kleiner Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of “pink pigmented facultative methylotrophs,” which can lead to wonderful “leaf prints.” Gnotobiotic versus “germ-free” animals. A solid review of the gut microbiome and the relationship to health. An article describing how proteins are digested by the microbiota. A description of glycan degrading enzymes and the gut microbiome. An overview of mucin. Description of metaproteomics by Dr. Kleiner. Description of metagenomics. Gut microbiota and dysbiosis. An overview of inflammatory bowel disease. An overview of Bacteroides thetaiotaomicron. An overview of Akkermansia muciniphila. The possibility of microbes “farming” us for mucus! The wide ranging and deeply fascinating website for Dr. Kleiner's research group. Dr. Kleiner's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this podcast, Dr. Anne Madden, founder of the Microbe Institute, shares why understanding microbes is important and why she is compelled to educate others.

Most dairy farms are trying to push the envelope from the conventional 4L of milk replacer per day to a higher volume to support lean structural growth of replacement heifers. Concerns of ruminal leakage resulting in fermentation has been cited as a concern, but is that based on an incomplete picture?  We know microbial protein offers a nearly perfect alignment of amino acid requirements for the bovine, however nutrition programs have discounted milk replacer to exclusively providing rumen undegradable protein (RUP) – protein that skips the rumen and is absorbed in the abomasum. Marcos Marcondes, researcher from the Miner Institute, wanted to see if feeding higher volumes would change the flow of protein and energy to the calf and the physiology of the rumen, due to leakage. To test this question he fed a standard rate and double rate of milk replacer with colbalt to mark and track the flow of digestion through preweaned animals. Leakage was found in the rumen on both treatments, but the results were positive. Energy, in the form of volatile fatty acids, and microbial protein added to the fuel for these growing animals.  Listen in to better understand the kinetics of digestion and questions that still remain for this phase of production. Topics of discussion 1:44       Introduction of Dr. Marcos Marcondes 2:50       Lambs as a model for bovine calves, 4 & 8L/day  4:07       Known info on the kinetics of milk protein 6:46       Relevance of microbial protein in fueling cattle 8:17       Cobalt marker used in the research model    10:51     Rumen leakage for preweaned calves   13:14     Grain feeding during trial 14:30     Milk replacer vs Whole milk 17:01    Retention rates 18:41    Colostrum protocol – no tubing 20:02    VFA and Microbial protein production 25:37    Physiology and histology 27:32    What do you want Boots on the Ground dairy producers to gain from the project?  Featured Article: Influence of different amounts of milk replacer on esophageal leakage, rumen fermentation characteristics, gastrointestinal tract passage rate, and microbial crude protein synthesis of nursling animals #2xAg2030; #journalofdairyscience; #openaccess; #MODAIRY; #prewean; #dairycalves; #microbialprotein; #MinerInstitute; #kinetics; #dairysciencedigest; #ReaganBluel;   

Buckle up for a fascinating journey through microbiome history! Dr. Siobhan McCormack welcomes the esteemed Professor Martin Blaser for an episode that travels through pivotal moments in microbiome science using a "Back to the Future"-inspired lens. Hear their engaging discussion, complete with time-traveling sound effects, as they explore Professor Blaser's career, the impact of antibiotics, and the critical importance of our microbial partners.This podcast is presented in collaboration with the British Society of Lifestyle Medicine.Disclaimer:The content in this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on this podcast.

Matters Microbial #86: Intraterrestrials — the Strangest Life on, and in, the Earth April 10, 2025 Today, Dr. Karen Lloyd, Professor of Earth Science at the University of Southern California,  joins the #QualityQuorum to discuss her upcoming book Intraterrestrials (Princeton University Press). Dr. Lloyd will describe the 25 year journey she and her coworkers have had exploring microbial life deep underground, and even less likely places. Host: Mark O. Martin Guest: Karen Lloyd Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The upcoming book, Intraterrestrials, by Dr. Lloyd. Definition of the term “intraterrestrial.” An interesting review article on intraterrestrial microbes. An video overview of extremophiles. An overview of the new field of geomicrobiology. A definition of “SLiME”s (subsurface lithoautotrophic microbial ecosystem). An article on microbial communities found deep underground. An article on “just underground” microbial communities that was just published. Remembering Dr. Katrina Edwards. Microbial communities in New Zealand hot springs. Radiolytic microbial communities. Photosynthesis by cyanobacteria via deep infrared light at hydrothermal vents (without sunlight). Microbes living under extreme acidic conditions:  the famed “snottites.” Microbes living under extreme alkaline conditions:  NPL-UPL2. How slowly can microbes divide? A fascinating video by Dr. Lloyd. Introducing Dr. Lloyd in her new position at the University of Southern California (an excellent overview of her work). Dr. Lloyd's faculty website. Dr. Lloyd's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In today's episode, we detail the enteric nervous system and regulation of gastrointestinal motility. We discuss factors including dysautonomia, stress, microbial overgrowth, and more, with regards to potential effects upon gastrointestinal motility. We further detail symptoms of altered GI motility. Topics:1. Introduction to Gastrointestinal Motility- Orchestrated contraction of smooth muscles that propel contents along the digestive tract.  - Roles in mixing, absorption, and preventing bacterial overgrowth.- Disruptions in motility. 2. The Enteric Nervous System (ENS) and Its Role- Myenteric and submucosal plexus.- Coordinating contractions and relaxations for effective motility. - Mucosa includes epithelium, lamina propria, and muscle.  - Submucosa houses the submucosal plexus.  - Muscularis externa. - Inner circular and outer longitudinal muscle layers with the myenteric plexus in between.   3. The Role of Interstitial Cells of Cajal (ICCs)- Specialized pacemaker cells in muscular layers  - Generate slow-wave electrical activity to synchronize smooth muscle contractions  - Critical for peristalsis.- Work with neural inputs to fine-tune gut motility   4. Dysautonomia and Its Impact on Gut Motility- Dysfunction of the autonomic nervous system (ANS)  - Motility impacts- Microbial overgrowth, SIBO 5. Gastrointestinal Dysmotility- Neurological dysregulation - Structural abnormalities and smooth muscle dysfunction  - Hormonal imbalances - Microbial overgrowth - Autoimmunity  6. The HPA Axis- Hypothalamus, pituitary gland, adrenal glands  - Central to the stress response and interlinked with gut function  - The amygdala and PVN of the hypothalamus  - CRH stimulates ACTH, leading to cortisol release from adrenal glands   7. Cortisol and Gut Barrier Function- Cortisol is a glucocorticoid that modulates immune function and gut physiology  - Chronic cortisol exposure can impair tight junction (TJ) integrity  - Increases paracellular permeability and allows passage of antigens and endotoxins   8.Stress-Induced Changes in Gut Motility- Slow gastric motility - Increased colonic motility  9. Symptoms of GI Dysmotility10. Addressing Root Cause(s)Thank you to our episode sponsor:1. Shop ⁠⁠⁠⁠⁠⁠⁠Fresh Press Farms⁠⁠⁠'⁠⁠⁠⁠⁠⁠⁠⁠Peach Cider Vinegar⁠⁠⁠⁠ at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Matters Microbial #85: The Microbiomes of Hawai'ian Seascapes April 3, 2025 Today, Dr. Rosie 'Anolani Alegado of the University of Hawai'i at Mānoa  joins the #QualityQuorum to discuss how weather, climate, and human intervention impact the microbiota to be found in human related seascapes around Hawai'i. Host: Mark O. Martin Guest: Rosie 'Anolani Alegado Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of how Hawai'i was settled from Polynesia. An essay describing indigenous Hawai'ian culture and its collaborative relationship to the land and sea. A must read book “Coral Reefs in a Microbial Sea,” by the late Merry Youle, Forest Rohwer, and Derek Vosten. Here are several links related to the work of Dr. Isabella Abbott, including this one from Pacific Science.  Again, well worth your reading. An overview of the field of ethnobotany, championed by Dr. Abbott. Dr. Alegado's previous research was with the fascinating choanoflagellates, which can tell us about the evolution of complex life.  Here is a video about these ancient relatives of us all.  Here is a article from Dr. Alegado describing a bacterial role in the development of this fascinating organism. An overview of the “One Health” concept linking human interactions, animals, plants, the land, and the ocean. A focus of Dr. Alegado's group research involving the indigenous Hawai'ian  fishponds. An overview of community restoration of these ancient structures. The role of taro in ethnobotany. A fine description of indigenous Hawai'ian mariculture. The concept of dysbiosis. Tropical storm Wali, which impacted the Hawai'ian Islands. An overview of alpha diversity and beta diversity in microbiome studies. A fine book about Dr. Barbara McClintock, “A Feeling for the Organism.” Here is a wonderful video in which Dr. Alegado describes the work of her research group and her interests in the fishponds of Hawai'i. Dr. Alegado's faculty website. Dr. Alegado's very interesting research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

We are virtually traveling in-field to learn more about microbial nitrogen and the impact biologicals and biostimulants can have on your crops. Dairy Stream host, Joanna Guza, and guest, Rick Molenaar, discuss the following topics:  Evolution of technology in crop production Gene-editing microbes Current advancements in microbial nitrogen Impressive corn silage research Key growing stages to focus on ROI benefit of nitrogen management How microbes can help dairy farmers Precision agricultural equipment Microbial nitrogen technologies to support GHG emissions Challenges Future of nitrogen fertilizer management Special thanks to Pivot Bio for sponsoring this episode. About the guest Rick Molenaar is a regional agronomy lead for Pivot Bio. He is an agronomy professional with a proven track record of success in leading field agronomist teams, conducting on-farm trials of pre-commercial biological products, and collaborating with land grant universities. His expertise spans Midwest row crop production, where he utilizes agriculture-based GIS programs to develop innovative variable rate maps for seeding, fertility, liming, and manure application, optimizing both crop yield and sustainability.  Resources Connect with Rick Molenaar on LinkedIn Scientific Reports: Genetic remodeling of soil diazotrophs enables partial replacement of synthetic nitrogen fertilizer with biological nitrogen fixation in maize, Purdue University & University of Wisconsin - Madison  Agronomy Journal: Soil inoculation with nitrogen-fixing bacteria to supplement maize fertilizer need, University of Illinois  Video Interview: Science Validated: Purdue & UW-Madison Confirm PROVEN 40's Mode of Action Past Dairy Stream episode with Co-Founder Karsten Temme: How microbes are shaping the future of crop nutrition Past Dairy Stream episode with Dr. Connor Sible of the University of Illinois: Understanding biologicals and biostimulants   Compeer Financial is proud partner of Dairy Stream.  Learn more about Dairy Stream sponsorship. This podcast is produced by the Voice of Milk, a collaboration of individual dairy organizations working to improve the future of dairy farm families. Become a sponsor, share an idea or feedback by emailing podcast@dairyforward.com. 

In this episode of the Beet Podcast, Kevin sits down with Michael Key, the brains behind Impello Biosciences, to dive deep into the fascinating world of biostimulants and microbial magic for plant health. From boosting productivity to promoting plant resilience, Michael unpacks the science behind these powerful tools. Tune in to discover how to apply these game-changing principles to make your garden flourish!  Connect with Michael Key: Michael Key is co-founder and CEO of Impello Biosciences, a Colorado-based company specializing in plant biostimulants and microbial solutions for agriculture. With a background in horticulture from Colorado State University, Michael authored several patents related to beneficial microbes and biochemical tools that enhance plant health and productivity. He combines scientific innovation with practical solutions to empower growers and promote eco-conscious farming practices. Find more from Michael Key at his website: https://impellobio.com  Support The Beet: → Shop: https://growepic.co/shop  → Seeds: https://growepic.co/botanicalinterests  Learn More: → All Our Channels: https://growepic.co/youtube  → Blog: https://growepic.co/blog  → Podcast: https://growepic.co/podcasts  → Discord: https://growepic.co/discord  → Instagram: https://growepic.co/insta  → TikTok: https://growepic.co/tiktok  → Pinterest: https://growepic.co/pinterest  → Twitter: https://growepic.co/twitter  → Facebook: https://growepic.co/facebook  → Facebook Group: https://growepic.co/fbgroup  → Love our products? Become an Epic affiliate! https://growepic.co/3FjQXqV Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Dairy Streamlet is a condensed version of a long Dairy Stream episode and covers the high-level points of the conversation. If this topic interest you, then listen to the full episode on April 2. We are getting an in-field perspective from an agronomist expert on the opportunities with microbial nitrogen. Dairy Stream host Joanna Guza and guest Rick Molenaar discuss gene-editing microbes, current advancements in microbial nitrogen, research, precision agricultural equipment and the future of nitrogen fertilizer management. Special thanks to Pivot Bio for sponsoring this episode. About the guest Rick Molenaar is a regional agronomy lead for Pivot Bio. He is an agronomy professional with a proven track record of success in leading field agronomist teams, conducting on-farm trials of pre-commercial biological products, and collaborating with land grant universities. His expertise spans Midwest row crop production, where he utilizes agriculture-based GIS programs to develop innovative variable rate maps for seeding, fertility, liming, and manure application, optimizing both crop yield and sustainability.  Compeer Financial is proud partner of Dairy Stream.  Learn more about Dairy Stream sponsorship. This podcast is produced by the Voice of Milk, a collaboration of individual dairy organizations working to improve the future of dairy farm families. Become a sponsor, share an idea or feedback by emailing podcast@dairyforward.com. 

In this episode, we detail the cellular make-up of the gastric lining, highlighting hydrochloric acid (HCl) secretion and its role in digestion, micronutrient absorption, and microbial defense. We discuss potential pathophysiological consequences of hypochlorhydria, including impaired digestive signaling, bacterial overgrowth in the small intestine (SIBO), and more. Lastly, we detail upstream microbial control, focusing on the influence of the oral microbiome and oral dysbiosis.Topics: 1. Introduction- Highlighting the stomach and hypochlorhydria / low stomach acid, as well as microbial balance, dysbiosis, and overgrowth.- Discussion of intestinal microbiome and oral microbiome. 2. Gastric Anatomy and Mucosal Layers- The stomach: cardia, fundus, body, pylorus.- The gastric mucosa: epithelial lining, lamina propria, muscularis mucosae.- The epithelial layer: mucous cells, parietal cells, chief cells, enteroendocrine cells.- Beneath the mucosa: submucosa and muscular layers that contribute to gastric motility, mechanical digestion, and more. 3. Mucous Cells - The surface epithelium and gastric pits.- Secretion of thick, viscous mucus.- Protecting the epithelium.- The mucus traps bicarbonate ions: neutral microenvironment that protects against acid-induced damage. 4. Parietal Cells and Gastric Acid Secretion- Secretion of hydrochloric acid (HCl): denatures dietary proteins, sterilizes ingested food.- Parietal cells produce intrinsic factor: binds vitamin B12 to facilitate absorption in the ileum. 5. Chief Cells and Pepsinogen- Secretion of pepsinogen: activated by low pH into the proteolytic enzyme pepsin.- Pepsin and protein digestion.- Release of gastric lipase. 6. Hydrochloric Acid: Digestive and Protective Roles- Immune defense.- Pepsinogen activation.- Adequate gastric acidity essential for properly acidified chyme.- Priming release of bile and pancreatic enzymes. 7. The Small Intestine, Stomach, and Microbial Regulation- The pyloric sphincter.- The stomach supports minimal microbial diversity.- Acidic barrier aids in limiting the entry of opportunistic microbes into the small intestine. 8. Hypochlorhydria, Low Stomach Acid- Hypochlorhydria can compromise one of the body's defense mechanisms.- Colonization of the small intestine.- Insufficient pepsinogen activation and possible protein digestion impairment.- Suboptimal chyme formation and downstream digestive capacity.- Possible symptoms of hypochlorhydria.- Possible impaired absorption of micronutrients including vitamin B12, iron, calcium, magnesium.- H. pylori infection, autoimmunity, aging. 9. The Oral Microbiome, Intestinal Microbiome, and Dysbiosis- Oral and environmental microbes.- Altered gastric pH, bile, digestive enzymes, and more.- The oral cavity as the gateway to the GI tract.- Oral microbial species.- Oral hygiene and oral microbiome health. 10. Conclusion- Root-cause approach.Thank you to our episode sponsor:1. Shop ⁠⁠⁠⁠⁠⁠Fresh Press Farms⁠⁠⁠'⁠⁠⁠⁠⁠⁠Peach Cider Vinegar⁠⁠⁠ at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Do you love #FUNGI? I do!! They are one of the most fascinating and interesting aspects of soil science - they are everywhere doing critical tasks and driving succession, remediation, growth, coherence, and so much more!! If you'd like to learn more with me - please sign up soon! The new season of Regenerative Soil Microscopy begins Monday!! Don't Miss It - Click Here: https://matt-powers.mykajabi.com/regenerative-soil-microscopy-the-online-course Watch the Video on Youtube: https://www.youtube.com/watch?v=GvKfprvT71s

Matters Microbial #84: Detecting Pathogens — and Worse — in Wastewater March 27, 2025 Today, Dr. Rachel Poretsky, Associate Professor of Biological Sciences at the University of Illinois Chicago joins the #QualityQuorum to discuss how examining wastewater (and related water) can give insights into the presence of pathogen antimicrobial resistance genes and even microbial ecology. Host: Mark O. Martin Guest: Rachel Poretsky Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A link to demonstrate the wonders of the Marine Biological Laboratories' Microbial Diversity course, which I know for a fact is life changing. Recommended by David Ranada, an article about water bottles and microbes.   An essay about the Chicago River and cholera, which led to the necessity of effective waste water treatment. An overview of the complexities of waste water treatment.  Here is a video on that topic.   An essay by Carl Zimmer about the microbial ecology of lakes…and human beings. How “recreational water quality” is determined. An article describing the microbiota associated with human biological waste with an amusing name (scroll down). How qPCR can be used to determine the prevalence of specific microbes. A recent article from Dr. Poretsky's research group, investigating how antimicrobial resistance genes can move through a hospital waste water system. A link to the Bacterial-Viral Bioinformatics Resource Center, for which Dr. Poretsky is a Principle Investigator. The Illinois state wastewater surveillance dashboard.  Fascinating! A Discovery Channel documentary on virus hunting and surveillance that includes Dr. Poretsky. Dr. Poretsky's faculty webpage. Dr. Poretsky's webpage for her research group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #83: Helicobacter — Passing the Acid Test March 19, 2025 Today, Dr. Karen Ottemann, Professor and Chair of the Department of Microbiology and Environmental Toxicology at the University of California Santa Cruz joins the #QualityQuorum to discuss the fascinating strategies of Helicobacter pylori, which can cause gastric ulcers and even stomach cancer in people. Host: Mark O. Martin Guest: Karen Ottemann Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of Helicobacter pylori and its relationship to gastric ulcers and gastric cancer. A video on the relationship between Helicobacteri pylori and gastric diseases. The story of how Helicobacter pylori was finally demonstrated to be responsible for gastric ulcers and gastric cancer. The prevalence of Helicobacter pylori world wide. When Helicobacter pylori does not cause disease:  a possible theory. The mechanism by which Helicobacter pylori causes gastric ulcers. The mechanism by which Helicobacter pylori causes gastric cancer. An overview of gastric cancer. An overview of inflammation and cancer. One of the articles from Dr. Ottemann's research group discussed in this episode:  “Bacterial flagella hijack type IV pili proteins to control motility.” Another of the articles from Dr. Ottemann's research group discussed in this episode:  “Helicobacter pylori cheV1 mutants recover semisolid agar migration due to loss of a previously uncharacterized Type IV filament membrane alignment complex homolog.” Dr. Ottemann's faculty website. Dr. Ottemann's research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Have you ever considered silver as a line of treatment?  Not only can topical silver-based products help with wound healing, but there's actually a TON of immune-boosting benefits from taking colloidal silver, too.  Expert and leader at Silver Biotics– Steve Revelli joins me today to show you how silver is redefining health, energy, and strength for so many people.  You already know I'm a big proponent of preventative medicine, especially when it comes to lowering inflammation, supporting gut and whole-body health, and healing our bodies naturally and effectively...  And silver products can help us do just that!  Silver Biotics has tons of diverse products that boost immune system health and benefit the whole body.  So check out the podcast here to discover the massive advantages of using silver, and grab a discount for your first order of Silver Biotics!  Steve Revelli Steve Revelli is the Chief Scientific Officer and R&D leader at American Biotech Labs. He's also a retired educator and former Adjunct Professor, bringing 30+ years of science and health education to his role. At Silver Biotics, he pioneers clean cosmetics and wound care products, merging science with wellness. IN THIS EPISODE What is colloidal silver, and how does it work? How silver is used in modern science and medicine Silver technology's interaction with the immune system  The importance of supplementation- particularly for women during midlife Unpacking myths around the use of colloidal silver  The future technology and uses of silver in medicine  Using silver for acute conditions or preventative measures  About Silver Biotics, and their effective supplements and products  QUOTES “What happens is you give an immune supplement that takes care of all the bioload and allows the immune system to do what it normally does and function a lot more efficiently, and that's what our silver does.” “What the immune system support does with our silver is it takes care of those pathogens. So you can have a good, healthy population of probiotics always in your gut.”  “The immune support that the silver does– it kills pathogens. It'll kill pathogens anywhere in the body.” RESOURCES MENTIONED Get Your Silver Biotics HERE ++ use code: DRMARIZA for 30% off your first order! Silver Biotics on Instagram  Silver Biotics on Facebook  RELATED EPISODES  #610: The Benefits of Spirulina and Chlorella for More Energy, Longevity, And Immunity with Catharine Arnston 591: Post Viral Syndromes, Your Immune System, And Your Hormones in Midlife with Dr. Jessica Drummond #334: 3 Immune-Boosting Habits That Are Non-Negotiable Right Now

Matters Microbial #82: Melanin, Fungi, and Global Warming March 13, 2025 Today, the impressive Dr. Arturo Casadevall of Johns Hopkins University returns to the podcast to discuss how fungal disease is a looming threat on our warming planet, and how these organisms can use pigmentation to adapt to human-associated environments . . . and increase their chances of causing disease. Host: Mark O. Martin Guest: Arturo Casadevall Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video overview of the understudied world of fungi. A CDC overview of fungal diseases. A hopeful study:  fungi, frogs, and purple bacteria.  A less scholarly but highly recommended essay is here. Dr. Casadevall's earlier visit to #MattersMicrobial. The story of Alexander Fleming, a stray fungal spore, and penicillin. The story of fungi and cyclosporins, which help with organ transplantation in humans. A recent New York Times article on fungal networks. An article about mass extinctions and “fungal overgrowth.” A review of the structure and function of melanin. An overview of how melanin can be used to turn various forms of radiation into energy. A review of high body temperatures versus fungal infections. One of the articles discussed today, from Dr. Casadevall's group:  “Impact of Yeast Pigmentation on Heat Capture and Latitudinal Distribution.” Another article from Dr. Casadevall's group discussed today:  “The hypothermic nature of fungi.” A really fascinating preprint from Dr. Casadevall's group discussed today:  “Thermal and pigment characterization of environmental fungi in the urban heat island of Baltimore City” Dr. Casadevall's faculty website. The research website for Dr. Casadevall's group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Dr. Edward DeLong is a Professor in the Department of Oceanography at the University of Hawai'i Mānoa as well as a Visiting Professor in the Department of Civil and Environmental Engineering at MIT. Research in Ed's lab brings together a variety of disciplines to study microbial communities in the ocean. He is interested in their ecology, evolution, biochemistry, genomics, and their impacts on marine systems. Particularly of interest for Ed are the microscopic organisms that are the primary producers or “forests of the ocean” responsible for releasing oxygen and serving as food for other organisms in marine food chains. When he's not working, Ed loves to be out in nature. He enjoys spending time outside with his family, hiking, kayaking, and snorkeling in the beautiful coral reefs near his house. Ed has also taken up yoga to help him stay limber and relaxed. Ed received his B.S. in Bacteriology from the University of California, Davis and his Ph.D. in Marine Biology from the Scripps Institute of Oceanography. Afterwards, he conducted postdoctoral research at Indiana University. Ed has worked as a research scientist at the Woods Hole Oceanographic Institute, a faculty member at the University of California, Santa Barbara, a research scientist at the Monterey Bay Aquarium Research Institute, and a faculty member at MIT before accepting his current position in Hawai'i. His honors and achievements include the Office of Naval Research Young Investigator Award, the DuPont Young Faculty Award, the Apple Bioinformatics Cluster Award, the Vladimir Ivanovich Vernadsky Medal of the European Geosciences Union, the Proctor and Gamble Award in Applied and Environmental Microbiology, American Society for Microbiology D.C. White Research and Mentorship Award, the UC Davis College of Biological Sciences Outstanding Alumni Award, A.G. Huntsman Medal for Excellence in Marine Science, and the Moore Foundation Marine Microbiology Investigator Award. Ed is also an Elected Fellow of the American Academy of Arts and Sciences, the National Academy of Sciences, the American Association for the Advancement of Science, and the American Academy of Microbiology. Ed has also been elected as an Associate of the European Molecular Biology Organization and is the Vice President and President Elect of the International Society of Microbial Ecology. In addition, he currently serves as the co-director of the Simons Collaboration on Ocean Processes and Ecology (SCOPE). Ed joined us for a conversation about his experiences in life and science.

SpaceTime Series 28 Episode 29The Astronomy, Space and Science News PodcastExploring Callisto's Ocean Potential, Laser Fossil Detection on Mars, and ISS Cleanliness ConcernsIn this episode of SpaceTime, we dive into exciting new research suggesting that Jupiter's moon Callisto may harbor a subsurface ocean, potentially making it another ocean world in our solar system. This revelation builds on data from NASA's Galileo spacecraft, which hinted at the presence of a salty liquid water ocean beneath Callisto's icy crust. Advanced modeling techniques have strengthened these claims, setting the stage for further exploration by NASA's Europa Clipper and ESA's Juice missions.Lasers on Mars: Searching for Ancient LifeWe also discuss innovative research that proposes using lasers to identify ancient microbial fossils on Mars. Scientists have successfully detected microbial fossils in gypsum on Earth, raising hopes that similar techniques could uncover evidence of past life on the Red Planet. The findings suggest that gypsum deposits on Mars could conceal traces of ancient life, preserved in mineral formations that formed when water evaporated billions of years ago.Health Implications of Sterility on the ISSAdditionally, we explore a new study indicating that the overly sterile environment of the International Space Station may be negatively impacting astronaut health. The research suggests that introducing a diverse range of microbes could potentially alleviate immune dysfunction and other health issues experienced by crew members during long missions in space.00:00 Space Time Series 28 Episode 29 for broadcast on 7 March 202500:49 New findings on Callisto's potential subsurface ocean06:30 Implications for future missions to Jupiter's moons12:15 Using lasers to detect ancient life on Mars18:00 Analysis of gypsum deposits and their significance22:45 Concerns regarding ISS cleanliness and astronaut health27:00 Overview of March's night sky and celestial events30:15 Celebrating PI Day and its significance in astronomywww.spacetimewithstuartgary.comwww.bitesz.com

Matters Microbial #81: Viruses, Innate Immunity, and Undergraduates March 5, 2025 Today, Dr. Brianne Barker, Associate Professor of the Biology Department at Drew University, joins the #QualityQuorum to discuss how her undergraduate research group studies how innate immune mechanisms of cells recognize viral invasion. Host: Mark O. Martin Guest: Brianne Barker Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video describing the immune system, both innate and adaptive. More of a focus on mechanisms of innate immunity, the focus for today. A description of basic immune cells. An introductory video describing the viral reproductive cycle in general. A description of PRRs (pattern recognition receptors) and MAMPs (microbially associated molecular patterns) An overview of interferons and disease. An introductory video overview of programmed cell death, called apoptosis. The role that retroviruses play in producing blue eggs in chickens.  Here is a very introductory summary.   The role that retroviruses play in placental mammals, including humans. How do cells recognize invading DNA during viral infection? A research paper by Dr. Barker's research group. Dr. Barker on This Week in Virology. Dr. Barker's faculty website. Dr. Barker's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #80: Do Microbes Make the Best Chemists? February 27, 2025 Today, Dr. Marc Chevrette, Assistant Professor of Microbiology and Cell Science at the University of Florida, joins the #QualityQuorum to discuss how his research group can study novel metabolites and even interactions via study of microbial genomes! Dr. Chevrette reminds us all that microbes are the best chemists! Host: Mark O. Martin Guest: Marc Chevrette Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode  An overview of how quickly the field of microbial genomics has advanced. How secondary metabolites can be important to antibiosis, cell signaling, and even communication. An overview of genome mining, along with another review. The program antiSMASH that analyzes genomes for genes involved with secondary metabolites. A video describing how antiSMASH can be used to search for possible biosynthetic gene clusters. An essay about Dr. Julian Davies. An article by Dr. Davies' group suggesting that antibiotics can serve as chemical signals between microbes. The idea of “parvomics,” studying the role of small molecules in how microbes communicate and interact. A great article from Dr. Chevrette and colleagues about how to look for biosynthetic diversity using genome mining. An article by Dr. Chevrette and colleagues exploring how groups of microbes can interact in remarkable ways. Dr. Chevrette's faculty website. Dr. Chevrette's research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this week's episode, we'll hear about a “belt and suspenders” approach to paroxysmal nocturnal hemoglobinuria, or PNH. We'll review long-term efficacy data for danicopan—an oral complement factor D inhibitor recently approved as an add-on to C5 inhibitor therapy.After that: researchers show how oral pathogens may exacerbate chronic graft-versus-host disease. And they assess targeted interventions to mitigate these effects. Finally, we move from the oral to the gut microbiome. New findings suggest that intestinal dysbiosis, induced by antibiotics, may adversely affect outcomes among patients who are receiving CAR-T cell therapy.Featured Articles:Long-term efficacy and safety of danicopan as add-on therapy to ravulizumab or eculizumab in PNH with significant EVHOral inflammation and microbiome dysbiosis exacerbate chronic graft-versus-host diseaseAntibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy

Matters Microbial #79: How Amoebae Beat the Heat February 20, 2025 Today, Dr. Angela Oliverio, Assistant Professor in the Biology Department at Syracuse University, joins the #QualityQuorum to discuss what her research group has been learning about extremophilic single-celled eukaryotes! Host: Mark O. Martin Guest: Angela Oliverio Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of protists.   A wondrous video of the types of protists to be found seemingly everywhere. A video about amoebae and how YOU can find them.   A video about the testate amoebae mentioned in this podcast. An essay about the testate amoebae. A very old article on temperature limits to eukaryotic life. A more modern article on this topic. An article from Dr. Oliverio's group on the temperature limits to eukaryotic life. The Mullin laboratory at UCSF does remarkable visualization. Genomics and the Lawrence Livermore Laboratory. How mycoplasma move, with remarkable videos. A member of Dr. Oliverio's lab creates beautiful glass art at this Etsy shop. A wonderful local news report on Dr. Oliverio and coworker's research. A nice overview of Dr. Oliverio's research interest in extremophilic protists. An article from Dr. Oliverio's group explaining why we should all care about extremophilic eukaryotes. Dr. Oliverio's research website (and SO worth your time) Dr. Oliverio's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #78: An EXTREME Close Up of the Squid-Vibrio Symbiosis February 13, 2025 Today, Dr Ariane Briegel, Professor and head of the Integrative Structural Cell Biology research unit at the Institut Pasteur in Paris, France, joins the #QualityQuorum to discuss some of the exciting findings of her research group studying how bacteria and the ever-popular Hawaiian bobtail squid work together at a  molecular level—using cutting-edge cryo-electron  tomography! Host: Mark O. Martin Guest: Ariane Briegel Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The (somewhat venerable) “The Eighth Day of Creation” discussed in this episode. A lovely article about the much missed Dr. Esther Lederberg.  Here is another I much enjoyed.  A website devoted to Dr. Esther Lederberg. A fun video reminder of the symbiosis between Vibrio fischeri and Euprymna scolopes.   A review of cryo-electron tomography as applied to the study of bacterial structures. A book coauthored by Dr. Briegel on the use of this technology to study cell-microbe interactions. A video on the topic of cryo-electron tomography. Another video by Dr. Briegel on this topic.   An earlier episode of #MattersMicrobial with Dr. Briegel. An article by the Moore Foundation that supports the work of Dr. Briegel. A article describing how cryo-EM can be applied to whole organisms, like roundworms.   Research websites for collaborators on this project, Dr. Edward Ruby and Dr. Margaret McFall-Ngai. Dr. Briegel's laboratory website. Dr. Briegel's academic website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #77: It's a Germ-Eat-Germ World! February 6, 2025 Today, Dr Laura Williams, Director of Undergraduate Research at Georgia Institute of Technology, joins the #QualityQuorum to discuss some of the exciting work she did as an associate professor at Providence College with undergraduate students studying predatory bacteria and why we should care about this fascinating topic! Host: Mark O. Martin Guest: Laura Williams Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A quite ancient review article describing the different classes of predatory bacteria by yours truly. A very important article on this topic by the late Dr. Lynn Margulis and colleagues. An article about my very inspirational first microbiology professor at UCLA, Syd Rittenberg, who did early work on Bdellovibrio. Several more up to date review articles on Bdellovibrio. The website of Dr. Liz Sockett (where both yours truly and Dr. Williams received some generous training). A quite interesting article by Dr. Sockett on Bdellovibrio. An article suggesting that predatory bacteria could be used as “living antibiotics.” An article describing the BALOs concept. The article described by Dr. Williams. Dr. Williams laboratory group website. Dr. Williams current faculty/administrator page. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Text a pool service question HERE!In this episode of the Talking Pools Podcast, Rudy Stankowitz dives deep into crucial topics affecting the pool industry, from upcoming trade shows—particularly the National Plaster Council Conference—to the nitty-gritty science of algae, microorganisms, and their impact on water quality and plaster integrity.Rudy also explores the controversial role of cyanuric acid in pool maintenance, the truth about advertising claims in the industry, and the latest insights into chlorine testing, pH control, and total alkalinity measurements.Additionally, this episode takes a practical turn as Rudy breaks down how to successfully raise your pool service prices without losing your mind—or your best customers. He explains how to time your price increases, handle customer reactions, and strategically communicate the change to maintain client loyalty and keep your business profitable.TakeawaysThe National Plaster Council Conference is a must-attend event for pool pros.Microorganisms in pools aren't just a nuisance—they impact plaster integrity and water quality.Cyanuric acid: a blessing and a curse in pool chemistry.Algae isn't just ugly—it's destructive (and Rudy has the science to prove it).Expired DPD2 reagents = faulty chlorine readings—don't trust bad data!Raising your pool service prices? The right approach makes all the difference.Timing is everything—adjust your pricing before peak season.Your best customers deserve a personal call when announcing a price increase.Don't let invoices deliver the bad news—own your worth!Trade shows are invaluable for networking and staying ahead of industry trends.The truth about chlorine testing: Manganese oxidation and expired reagents can throw off results.Evaporation affects chemical concentrations, which can mislead pool pros on water balance.Sound Bites"We made it to another Friday.""We're going to do a deep dive.""Raise your pool service prices—the right way!""Microbial acid secretion—it's real, and it's coming for your plaster.""If the drop has a purple hue, it has expired.""The ideal pH range is 7.4 to 7.6.""High levels of metal can affect test results."Chapters00:00 – Introduction to Pool Talk and Industry Events04:36 – Upcoming National Plaster Council Conference10:01 – Deep Dive into Algae and Microorganisms17:23 – Cyanuric Acid: Friend or Foe?20:53 – Advertising Truths in the Pool Industry23:09 – Understanding Chlorine Testing and Measurement26:39 – Raise Your Pool Service Prices the Smart Way28:10 – The Importance of pH Levels32:22 – Chlorine Levels and Their Impact35:28 – Total Alkalinity Testing Explained38:18 – Calcium Hardness and Leak Detection42:45 – Managing Metal Contamination in Pool Water46:22 – Strategies for pH Control in Saltwater Pool Support the showThank you so much for listening! You can find us on social media: Facebook Instagram Tik Tok Email us: talkingpools@gmail.com

Matters Microbial #76:  Marvelous Multicellular Magnetotactic Microbes! January 29, 2025 Today, Dr. George Schaible, Postdoctoral Scholar at the University of California, Santa Barbara, joins the #QualityQuorum to discuss the exciting work he did during his PhD to unravel a fascinating topic:  multicellular magnetotactic microbes!   Host: Mark O. Martin Guest: George Schaible Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode What is a postdoctoral scholar in microbiology?  A previous #MattersMicrobial podcast about giant bacteria from Dr. Esther Angert.   A previous #MattersMicrobial podcast about magnetotactic bacteria from Dr. Arash Komeili. A previous #MattersMicrobial podcast about multicellularity in microbes from Dr Will Ratcliff.   The transformative Microbial Diversity Course at the Marine Biological Labs at Woods Hole, Massachusetts. An article describing the value of the Microbial Diversity Course.  I wrote this blog post on Chlorochromatium aggregatum consortium for Small Things Considered many years ago.   The “pink berry” consortium at Woods Hole. A research paper on genetic interactions within the pink berry consortium, coauthored by a former undergraduate researcher of mine, Dr. Danielle Campbell.  Yes, I am very proud. A strategy to easily enrich for magnetotactic bacteria from nature. Here is a video that informs and amuses.   An early report of multicellular magnetotactic microbes. The research article under discussion in today's podcast. A link to Dr. Roland Hatzenpichler's laboratory website (Dr. Hatzenpichler was the originator of this research, all the way back to his own attending the Microbial Diversity Course.). The deeply strange genome(s) of Achromatium. An introduction to nanoSIMS technology. An introduction to stable isotope probing. The laboratory website of Dr. Jean-Marie Volland, where Dr. Schaible works at UC Santa Barbara Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

“Farm and Ranch Profitability all Starts in the Soil.” Terry Buettner serves as the Account Development & Agronomy Support Manager for Ward Laboratories Inc. based out of Kearney, Neb. Ward Laboratories are Graze Master Group partners. Buettner joined Ward Laboratories in the fall of 2017. He graduated from the University of Nebraska – Kearney in 1983 with a B.S. in Business Administration. He has been involved in production agriculture and seed sales in the Kearney area for 34 years. During this Underdog Ag Podcast, Buettner will discuss the Ward Laboratories Soil Health Assessment as well as Soil Health Principles that lead to increased fertility, more productive land, and more. Below is more information about the assessment that benefits farmers and ranchers in numerous ways. About the Ward Laboratories Inc. Soil Health Assessment: Looking to boost your dollars per acre at harvest time? It all starts in the soil. Your plants are only as healthy as the soil they are feeding from. Reduced microbial activity and limited nutrient availability can result in lackluster harvests. Ward Laboratories can give you a complete report of our findings and recommend corrective measures. The new Soil Health Assessment (SHA) package is a test that combines the latest in soil science, ensuring that both soil fertility and soil health are viewed through a single test, helping farmers and researchers measure and manage soil health without compromising productivity. Microbial activity and food are evaluated to provide data that enhances operations while also evaluating nutrients in a manner that is widely accepted by Land Grant University correlations and calibrations. This new package also includes modified aggregate stability. With this addition, the new Soil Health Assessment offers two biological, one chemical and one physical indicator of soil health. Learn more at:www.wardlab.com/services/soil-health-analysis/www.grazemastergroup.com--Be sure to rate, review, and subscribe.HOST: Kerry HoffschneiderGUEST:  Terry Buettner--CREDITS:Mitchell Roush, ProducerBibi Luevano, Cover ArtPurple Planet Music, Theme

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Matters Microbial #75: Do Gut Microbes Watch their Carbs?   January 22, 2025 Today, Dr. Darrell Cockburn, Associate Professor of Food Science at Penn State, joins the #QualityQuorum to discuss the work his research group has done exploring how starches and other polysaccharides are used by the gut microbiome.  Host: Mark O. Martin Guest: Darrell Cockburn Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of dietary fiber in the diet. A primer on the structure of starch and cellulose. An overview on starch granules. The concept of food gelatinazation. An overview of “resistant” starch. How Febreze works! The concept of the glycemic index of foods. An article about resistant starch and colon microbiota.  Another article on this topic. A primer on carbohydrate binding modules. An article describing the role of short chain fatty acids in digestion. An article suggesting that there is no perfect microbiome. An interesting article from Dr. Cockburns research group showing that microbes can work together to digest resistant starch. Dr. Cockburn's academic website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Doug Drysdale Chief Executive Officer An experienced Corporate Director and CEO: Doug has chaired the board of directors of a NASDAQ-listed company and, as a CEO for the past 12 years, has built and turned around three pharmaceutical companies. Doug has 30 years of experience in the healthcare sector. During this time, he has formed cohesive management teams, recruited board members, completed 15 corporate acquisitions across three continents, and raised $4 billion in public and private capital. Led the turnaround of Norwich Pharmaceuticals alongside investors and became the Founding CEO of the parent company, Alvogen Group. During his 5.5-year tenure as CEO, Alvogen grew from inception to $450 million in revenues across 35 countries. In early 2014, Doug led the recapitalization of NASDAQ-listed Pernix Therapeutics, raising $65 million. Within the first year of taking the helm as Chairman and CEO, Doug rebuilt the management team and board of directors, combined several operating locations, and grew the company's enterprise value from $80 million to around $800 million. Under Doug's leadership, Pernix raised $465 million of capital. From November 2017 to July 2020, Doug was the Director and CEO of Tedor Pharma, a family-owned contract manufacturing business. Doug's efforts to turn around the industry resulted in 60% revenue growth in 2019, leading to Tedor being recognized as one of America's fastest-growing companies and making it to the 2020 Inc 5000 list. Former Head of M&A at Actavis Group, leading 15 corporate acquisitions across three continents between 2004 and 2008, including a high-profile public hostile takeover attempt in Central Eastern Europe. Over this period, Doug raised approximately $3 billion in capital and managed lending syndicates, including 25+ banks, to fund the company's growth. Actavis was sold to Watson Pharmaceuticals in 2012 for EUR4.25 billion. Doug holds a bachelor's degree in Microbial and Molecular Biology from the University of East Anglia in the U.K. and was recognized as Ernst and Young's Entrepreneur of the Year in 2012. He is an enthusiastic traveler, having visited over 45 countries. He is also an avid reader and enjoys cooking and boating. This video was conducted on behalf of Cybin and was funded by Gold Standard Media LLC and/or affiliates. For our full disclaimer, please visit https://portal.goldstandardir.com/disclaimer/CYBN-183   https://ir.cybin.com/overview/default.aspx NYSE: CYBN I CBOE: CYBN   Addressing Mental Health Challenges Doug and Michael discussed the challenges and frustrations faced by patients and doctors in dealing with mental health issues, particularly clinical depression. With his background in building drug development companies, Doug highlighted the lack of practical tools for addressing these issues. Michael expressed his interest in innovative solutions to mental health problems, given his personal experience with clinical depression. The conversation was set to be more organic and conversational, with Doug sharing more about his company and their approach to mental health. Paradigm Shift in Drug Development Doug expressed his belief that their work has the potential to be a paradigm shift in drug development, moving from daily treatment of symptoms to more interventional therapies that can rapidly fix conditions like depression. He highlighted the promising results from their studies, with patients experiencing benefits lasting at least a year after just a couple of doses. Michael shared his personal experience with depression and burnout, emphasizing the importance of their work in addressing this widespread issue. He also asked Doug about his ability to anticipate future challenges and steps in the approval process for their work. Drug Development Challenges and Success Doug discussed the challenges and complexities of drug development, particularly in the mental health sector. He highlighted the team's experience and success in developing treatments, with 60+ INDs and 37 exits. Doug also emphasized the personal motivation of the team members, many of whom have been affected by mental health issues. He acknowledged the regulatory hurdles and administrative complexities involved in drug development but stressed the importance of these steps in creating effective treatments. Michael added that the success of the treatments could also positively impact the revenue of psychiatrists and their practices. Improving Mental Health Care Efficiency Doug discussed the potential of a new treatment to improve mental health care. He highlighted that depressed patients require a lot of attention, often visiting their physicians multiple times a year for medication adjustments and dealing with side effects. He also pointed out the shortage of psychiatrists and the long wait times for new patients. Doug suggested that their treatment, which only requires dosing once or twice, could keep patients out of the system for at least a year, freeing up resources for new patients. He also mentioned the potential for interventional psychiatry centers to see more patients if the treatment reduces the required visits. Mental Health and Metabolic Connection Michael and Doug discussed the challenges of mental health, particularly financial stress and depression. Michael shared his personal experience of overcoming depression with the help of medication and therapy and expressed his excitement about the potential of innovative work in mental health. Doug emphasized the link between metabolic health and mental health, suggesting that a poor diet can lead to reduced mental function and that mental health issues can affect an individual's metabolic health. Both agreed on the importance of addressing mental health issues to improve overall well-being and happiness. Phase 3 Program Progress and Strategy Doug discussed the progress of their phase 3 program, focusing on the challenges and complexities involved, such as drug scheduling and licensing. He expressed optimism about the potential of their treatments, citing their significant effects and the absence of dosing every day in their studies. Doug also outlined their long-term strategy, which includes leveraging their phase 3 approval in depression to treat other conditions and shift from daily chronic dosing to more interventional treatments. He emphasized the potential to break the cycle of polypharmacy and create a platform for various treatments. Michael supported their work and encouraged more people to learn about their efforts.  

Matters Microbial #74: Podcasting to Combat Microbial Misinformation January 16, 2025 Today, Dr. Jessica Coates of the Biology Department at Spelman College joins the #QualityQuorum to discuss her work combating microbial misinformation in the classroom and to share her journey to the microbial sciences.   Host: Mark O. Martin Guest: Jessica Coates Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A short talk I gave at ASM some time ago about Louis Pasteur and the term “germ.” An organization devoted to promoting microbial literacy. An example of using podcasting to increase learning outcomes in the STEM classroom. An example of using podcasts by scientists to promote learning by students. The interesting story of Spelman College. An interview with Dr. Coates. The academic website of Dr. Coates. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #73: Seeing the Microbiome January 8, 2025 Today, Dr. Travis Wiles, Assistant Professor of Molecular Biology and Biochemistry at the University of California, Irvine, joins the #QualityQuorum to discuss the work he and his research group have done to visualize the changing dynamics of the gut microbiome—including bacteriophages residing there.  Host: Mark O. Martin Guest: Travis Wiles Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Dr Anne Estes' academic website is found here, along with her blog, and her social media link on Bluesky.  So many interesting ideas! Transgenic zebrafish as pets are called GLOfish. Use of zebrafish as a model system for developmental biology. An article exploring the effects of the microbiome on gnotobiotic (“germ free”) zebrafish. An essay on both lytic and lysogenic bacteriophages. An essay describing how bacteriophage interact with the gut microbiota.  One of my former undergraduate research students, Dr. Danielle Campbell, works in this area! An article suggesting that bacteriophage do in fact interact with eukaryotic cells. The concept of phage conversion:  how some bacteriophages carry bacterial genes, including toxin genes. An article about bacteriophages and bacterial evolution. An article about the study of the zebrafish gut microbiome. An article about research with zebrafish and Mycobacterium.  The article discussed in this episode by Dr. Wiles' group: “Phollow: Visualizing Gut Bacteriophage Transmission within Microbial Communities and Living Animals .”    Dr. Wiles' academic website. Dr. Wiles' very colorful and interesting laboratory group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #72: Who is in Your Water? January 2, 2025 Today, Dr. Ameet Pinto, Carlton S. Wilder Associate Professor in Civil and Environmental Engineering at the Georgia Institute of Technology, joins the #QualityQuorum to discuss the microbiome of drinking water and how it can be used to optimize safety and health.  Host: Mark O. Martin Guest: Ameet Pinto Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A short review of a famous article by Dr. Norman Pace about the microbiome of showers and how microbial populations differed due to chlorination. An old discussion of microbial oligotrophy:  the ability to survive on very low levels of nutrients. The story of John Snow, a water fountain, and cholera in England. The concept of “Live/Dead” staining of microbes. An overview of the concept of metagenomics. An article on the microbiome of shower hoses. A public science outreach program to study the microbiome of showerheads. The Instagram link for Dr. Pinto's wonderful cat, Nessie. A great book describing exceptions to Mendelian genetics using cats:  “Cats Are Not Peas.”  Highly recommended. An article about water supplies and the pathogenic microbe Legionella. An overview of water disinfection techniques. An introduction to a model system of a microbial soil community, called THOR by Jo Handelsman and colleagues. Thinking of water treatment and related technologies as a series of ecological niches, via Tom Curtis and Bill Sloane. Dr. Pinto's faculty website. Dr. Pinto's deeply fascinating research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #71: Disinfecting the Built Environment December 25, 2024 Ever wonder what's growing on your toothbrush? Today, Dr. Erica Hartmann, Associate Professor of Civil and Environmental Engineering at Northwestern University, joins the #QualityQuorum to discuss how antimicrobial resistance can occur in the built environment we see all around us every day—and why it is vital to learn more about this association. Host: Mark O. Martin Guest: Erica Hartmann Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An essay on the Hygiene Hypothesis. An overview of the “built environment.” The trouble with triclosan. An essay on heavy metal resistance. An article from Dr. Hartmann's group about the toothbrush microbiome (“Project Pottymouth”). A link to the Human Microbiome Project. An overview of antibiotic resistance and antibiotic resistance genes. An article about silver nanoparticles on toothbrushes. A blog post about probiotic cleaning products. An interesting post from Dr. Hartmann's team about viruses in your bathroom. A video by Dr. Hartmann about her research. Dr. Hartmann's faculty website. Dr. Hartmann's research team website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

How Probiotics Affect Fat Loss, Muscle Building & Cognition with Dr. Zain Kassam Dr. Kassam's background in the space. (1:42) How important is our relationship with our microbiome? (7:01) The connection between our microbiome and the explosion of autoimmune disorders. (8:47) Are these problems inherited? (11:56) Two pathways to consider why obese mice get skinny when getting the right microbes. (13:02) How are they using AI? (16:31) Why does the gut influence our brain? (18:40) Can our microbiome influence our cravings? (22:11) Our microbiome's connection to our muscle mass. (23:22) How can we use this science in the future? (26:25) The 4 D's of picking a probiotic. (32:05) The transient effect of taking a daily probiotic. (34:41) How can we restore a ‘leaky gut'? (36:30) Not all probiotics are created equal. (38:42) Science is not complete until it's communicated. (40:00) How do you know you're getting live bacteria? (43:26) How does he maintain good microbiome health? (45:13) Understanding antibiotics. (48:49) Are probiotics beneficial to take while on antibiotics? (50:11) Probiotics effect on performance. (54:48) Galaxy class solution. (56:31) His take on GLP-1s. (58:54) Related Links/Products Mentioned Visit Seed for an exclusive offer for Mind Pump listeners! **Promo code 25MINDPUMP at checkout for 25% off your first month's supply of Seed's DS-01® Daily Synbiotic** Limited Launch Promotion: MAPS 15 Performance public launch price: $87! ** Code 15PLAUNCH for $20 OFF. Free Bonuses: 30-Day Landmine Workout + 7-Day Overtraining Rescue Guide. ** December Promotion: MAPS Aesthetic | MAPS Symmetry 50% off! ** Code DECEMBER50 at checkout ** Antibiotic exposure and ‘response failure' for subsequent respiratory tract infections: an observational cohort study of UK preschool children in primary care Altering mix of gut microbes prevents obesity, but diet remains key factor Microbial-based treatment reverses autism spectrum social deficits in mouse models Muscle strength is increased in mice that are colonized with microbiota from high-functioning older adults Impact of probiotics on muscle mass, muscle strength and lean mass: a systematic review and meta-analysis of randomized controlled trials VCU receives $11.5 Million NIH grant to study the vaginal microbiome and its relevance to disease, genetics and the environment Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT Seed-Science Mind Pump Podcast – YouTube Mind Pump Free Resources  

Space Nuts Episode: Ryugu's Microbial Mystery, Martian Moon Origins, and Galactic CollisionsJoin Andrew Dunkley and Professor Fred Watson as they explore the latest cosmic revelations. From unexpected microbial contamination of Richie asteroid samples to a groundbreaking theory on the formation of Mars's moons, and the first results from a new instrument on the William Herschel Telescope, this episode is packed with stellar insights and astronomical wonders.Episode Highlights:- Richie Asteroid Contamination: Delve into the challenges of keeping extraterrestrial samples free from Earth's microbes. Despite stringent sterilisation efforts, Richie samples returned by Hayabusa2 show signs of terrestrial contamination, raising questions about planetary protection protocols.- Martian Moons' New Origin Theory: Discover a fresh perspective on how Phobos and Deimos may have formed. A new model suggests that these moons originated from debris of an asteroid that broke apart due to Mars's gravitational forces, offering an alternative to previous impact and capture theories.- Galactic Collisions Unveiled: Explore the first findings from the WEAVE instrument on the William Herschel Telescope. By studying Stefan's Quintet, astronomers reveal the staggering speeds of shock waves from colliding galaxies, shedding light on cosmic interactions and future Milky Way-Andromeda collision scenarios.For more Space Nuts, including our continually updating newsfeed and to listen to all our episodes, visit our website. Follow us on social media at SpaceNutsPod on facebook, X, YouTube, Tumblr, Instagram, and TikTok. We love engaging with our community, so be sure to drop us a message or comment on your favourite platform.For more Space and Astronomy News Podcasts, visit our HQ at www.bitesz.com.Become a supporter of this podcast for extended commercial-free episodes and more. Visit our Support page for options: spacenutspodcast.com/aboutStay curious, keep looking up, and join us next time for more stellar insights and cosmic wonders. Until then, clear skies and happy stargazing.00:00 - Andrew Dunkley: Coming up on this edition of Space Nuts01:15 - This episode will be officially released two days after your 800th birthday02:29 - Justin Jackson says Ryugu samples show effort to keep them clean has failed12:12 - If that can happen in a room that's designed not to allow it12:47 - New theory put forward about origin of moon's phobos and Deimos21:22 - Andrew Dunkley says spherical potatoes could be useful in space missions22:46 - Fred looks at an instrument connected to the William Herschel telescope26:45 - Professor Gavin Dalton has been working on the William Herschel Telescope31:30 - We've got similar collision speeds as Andromeda.✍️ Episode ReferencesImperial College London[imperial.ac.uk](https://www.imperial.ac.uk/)Meteoritics and Planetary Science Journal[wiley.com](https://onlinelibrary.wiley.com/journal/19455100)phys.org[phys.org](https://phys.org/)Durham University[durham.ac.uk](https://www.dur.ac.uk/)NASA Spaceflight[nasaspaceflight.com](https://www.nasaspaceflight.com/)JAXA (Japanese Aerospace Exploration Agency)[jaxa.jp](https://www.jaxa.jp/)William Herschel Telescope[ing.iac.es](http://www.ing.iac.es/astronomy/telescopes/wht/)Isaac Newton Group of Telescopes[ing.iac.es](http://www.ing.iac.es/)Become a supporter of this podcast: https://www.spreaker.com/podcast/space-nuts--2631155/support.

On this week's edition of the Beyond Clean Expert Series On-The-Go, tune in for the conversation entitled, "Microbial Warfare: Winning with UV Technology," with our UV Disinfection Expert™, Daan Hoek. To hear more from this expert, follow us on Facebook and LinkedIn, or subscribe to the Beyond Clean mailing list by visiting: http://www.beyondcleanmedia.com Do you know a #SterileProcessing expert who you'd love to hear from on our series? Or do you have a question for one of our current experts? Contact us at any time via email at: info@beyondclean.net Until next time, keep fighting dirty! #BeyondClean #ExpertSeries #Podcast