Podcasts about microbial

In this encore episode, we detail the oral-gut microbiota axis, detailing the oral microbiome and its relationship with the intestinal microbiome. We discuss the development of oral biofilm, the transition from plaque to dental calculus, and potential impacts of oral dysbiosis, while highlighting intestinal health and focusing on Fusobacterium nucleatum. Topics:1. Overview of the Oral Microbiome and the Oral-Gut Axis - The oral cavity and the gut: microbially dense sites. - Anatomically distinct but connected and capable of influencing each other. - The oral microbiome. - Microbial distribution: topography and chemistry of oral surfaces. 2. Oral Cavity Anatomy and Microenvironments - The vestibule and oral cavity proper. - Lined by oral mucosa, which varies in structure. - Unique ecological niches that support different microbial populations. 3. Tooth Structure and Relevance to Microbial Colonization - Teeth are embedded in the alveolar processes of the maxilla and mandible. - Tooth structure. - Long-term microbial colonization and biofilm development. 4. Biofilm / Dental Plaque Development - Biofilm begins with the formation of the acquired pellicle.- Pioneer species secreting extracellular polymeric substances (EPS).- Secondary colonizers coaggregate.- Coaggregation is species-specific.- Example.- Aerobes can lower local oxygen levels, creating micro anaerobic niches that support obligate anaerobes. 5. Maturation of the Biofilm  - Biofilm composition shifting to anaerobic, proteolytic species such as P. gingivalis. - F. nucleatum: a bridge species. 6. Mineralization and Formation of Dental Calculus - Mineralization, calcium and phosphate deposition. - Dental calculus. 7. Oral Dysbiosis  - An imbalance in the oral microbial community. - Potential signs and symptoms. - Halitosis, swollen or bleeding gums, tooth sensitivity. 8. Oral-Gut Axis and Systemic Implications - Physical, chemical, biochemical, and immunological barriers aid in preventing oral bacteria from colonizing the gut. - Oral bacteria can potentially impact intestinal health. -  F. nucleatum and IBD. 9. Oral Microbiome Testing10. Multi-Factorial Thank you to our episode sponsors: 1. ⁠⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.3. ⁠Codex Labs⁠: Explore Codex Labs' collections for ⁠acne⁠, ⁠eczema⁠, and more. Shop the ⁠BIA Collection HereGet Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Michael Lynch, Ph.D., Director of the Center for Mechanisms of Evolution at Arizona State University and Vaughn Cooper, Ph.D., professor of Microbiology and Molecular Genetics at the University of Pittsburgh, School of Medicine, examine the origins and trajectory of early microbial life (EML) and discuss the collaborative report between the American Academy of Microbiology and the Gordon and Betty Moore Foundation, which explores the journey of life on Earth, from non-living chemical compounds to early unicellular life, to the vast diversity of organisms we see today. This episode is brought to you by the American Academy of Microbiology, a think tank at American Society for Microbiology and the Gordon and Betty Moore Foundation, which has been dedicated to advancing scientific discovery for the past 25 years. Links for This Episode: Project Report Early Microbial Life: Our Past, Present and Future. Article: The Great Oxidation Event: How Cyanobacteria Changed Life. MTM Podcast: From Hydrothermal Vents to Cold Seeps: How Bacteria Sustain Ocean Life With Nicole Dubilier. Take the MTM listener survey! 

Matters Microbial #104: Antibiotic “Tolerance” and Biofilms August 21, 2025 Today, Dr. Boo Shan Tseng, Associate Professor at the University of Nevada Las Vegas School of Life Sciences, joins the #QualityQuorum to discuss bacterial biofilms and antibiotic tolerance.  Host: Mark O. Martin Guest: Boo Shan Tseng Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video overview of biofilms. A comprehensive review article on biofilms. An article describing the impact biofilms have on disease. An article describing the impact of biofilms on implanted medical devices. A link to the Center for Biofilm Engineering at Montana State University that has MANY links of interest. An overview of biofilm development. An overview of confocal laser microscopy. Studying biofilms in flow cells. An article about the role proteins play in biofilm formation, which intersects with the Tseng group's research. The technique of single cell RNA seq. The technique of mRNA-FISH. An article about porins in bacteria, and how that can relate to antibiotic resistance. An article by Dr. Tseng and coworkers on the eDNA and biofilms discussed today. A lovely video of Dr. Tseng talking about the research she and her colleagues carry out in the laboratory. Dr. Tseng's biography from the American Society for Microbiology. Dr. Tseng's laboratory group website with wonderful links and images. Dr. Tseng's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

My guest today is Dr. Kenda Rigdon. Dr. Rigdon is a microbiologist with a PhD in microbiology and virology from the University of Alabama at Birmingham. Drawing from her expertise, she explores how the gut's microbial ecosystem—comprising bacteria, yeast like Candida and Malassezia, and other microbes—interacts with genetic and epigenetic factors to influence Autism. Dr. Rigdon highlights the critical role of the birthing process, particularly how vaginal delivery seeds a newborn's gut with beneficial microbes like lactobacillus, setting the stage for healthy development in the first three years. She also delves into how yeast overgrowth, nutrient competition (e.g., for tryptophan), and environmental factors like manganese and glyphosate exposure can disrupt this delicate ecosystem, potentially exacerbating autism-related symptoms.Dr. Rigdon shares insights into the surprising links between melanin, Neanderthal DNA, and Autism. She discusses how specific genetic mutations, such as MTHFR and PAI1, can intersect with Autism. Additionally, she connects melanin production—potentially influenced by gut yeast like Malassezia—to neurological health, drawing parallels with conditions like Parkinson's. By viewing the gut as a dynamic ecosystem shaped by birth, diet, and early development, this episode offers a fresh perspective on Autism's microbial roots and practical implications for health, urging listeners to reconsider modern birthing practices and dietary choices in fostering a balanced gut microbiome.Dr. Rigdon X https://x.com/KendaRigdonDaylight Computer Companyuse "autism" for $25 off athttps://buy.daylightcomputer.com/RYAN03139Chroma Iight Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism0:00 Dr. Kenda Rigdon1:14 Journey into Microbiology4:08 The Gut's Ecosystem8:21 Genetics, Autism, & The Microbial Connection13:08 MTHFR & PAI1: Homocysteine, Methionine, Folate20:21 The Role of Yeast in Health & Disease; Serotonin, Candida26:39 The Fight for Tryptophan31:14 Impact of Birthing Method on Gut Health (!)33:13 Modern versus Evolutionary Births, Breastfeeding; Oxygen, Acidity, PH37:15 Melanin, Cell Protection, Neanderthal DNA, Autism40:46 Neuromelanin; Biological Energy, Melanocytes43:20 Neanderthal's & Modern Disease & Environments47:23 Microbes in the Brain53:21 Manganese & Gut Health58:22 Gut-Brain Connection & Microbial Balance01:03:19 Early Gut Health & Development; Modern Insults01:07:21 Future Direction in Gut Health & Kenda's Passion & LoveX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Matters Microbial #103: Giant Bacteria and Bigger Questions August 14, 2025 Today, Dr. Jean-Marie Volland, Assistant Professor at the University of California in Santa Barbara joins the #QualityQuorum to discuss the discovery and analysis of the (so far) largest bacterium known:  Thiomargarita magnifica, which can be a centimeter long! Definitely #OMG and #WTM! Host: Mark O. Martin Guest: Jean-Marie Vollard Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a review article discussing the environmental persistence of antibiotic resistance genes. Here is a link to Episode 41 of this podcast, with Dr. Esther Angert, on the wily ways of Epulopiscium. A review article regarding “giant bacteria.” A video explaining the surface area versus volume issue discussed on this podcast. An interesting article exploring how much “territory” is within a bacterial cell; this is relevant to bacterial polyploidy. A review of Epulopiscium, the first of the giant bacteria described. Here is a video of Epulopisicum.   An article describing polyploidy in Epulopiscium.  A review of Thiomargarita nambiensis, another giant bacterium with an interesting strategy. Here is a video of T. nambiensis.  An essay from “Small Things Considered” about the very, very strange world of Achromatium, which is so worth your time. The first report of Thiomargarita magnifica, the world's largest bacterium (thus far) by Dr. Volland and coauthors. Here is a report on this discovery for novice micronauts. A great review about giant microbes by Dr. Volland. A more recent article on T. magnifica by Dr. Volland and colleagues. A video regarding T. magnifica. A video by Dr. Volland describing T. magnifica work. A lovely essay regarding how Dr. Volland and family trekked California searching for giant microbes. Don't miss! The research lab website for Dr. Volland and colleagues, with so much interesting information. The faculty website for Dr. Volland at UC Santa Barbara. Intro music is by Reber Clark

Kilayim [Part 2]: Keeping a kilayim tree; Bracha on blossoming tree; Shehechiyanu on Rosh Hashanah; Microbial fermentation. See seforim by Rabbi Cohen at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.kashrushalacha.com⁠

Matters Microbial #102: Teaching Through the Issues with Microbes! July 31, 2025 Today, Dr. Davida Smyth, Professor of Biology and Deputy Director of the National Center for Science and Civic Engagement at Texas A&M University-San Antonio joins the #QualityQuorum to discuss her impressive work using microbiology to engage students at the intersection of cutting edge research and current events. #MicrobialLiteracy! Host: Mark O. Martin Guest: Davida Smyth Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The American Society for Microbiology Carski Award website. The American Society for Microbiology Distinguished Lecturer website. The concept of “classroom agreements.” The 10:1 (microbial cells to human cells) story, and a related article. The 3-2-1 approach to learning in the classroom. Dr. Smyth's “How Toilets Changed the World” class. The American Society for Microbiology Curriculum Guidelines. The National Science Foundation's “Vision and Change” website describing improvements in biology education. The American Society for Microbiology profile for Dr. Smyth. A video seminar by Dr. Smyth describing open science in undergraduate education. The website for the National Center for Science and Civic Engagement. Dr. Smyth's faculty website. Dr. Smyth's superb research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

If you've struggled with gut imbalances, recurrent or chronic infections, or you're just curious about upgrading your oral or gut microbiome, this episode of Vitality Radio is a must-listen. Jared welcomes Dr. Shawn Manske, ND, from the Biocidin Clinical Education team to dive deep into one of the most respected formulas in the natural health world—Biocidin. With over 35 years of clinical use and growing popularity, Biocidin is finally available to the public, and it's making a big impact. Dr. Manske breaks down how this unique botanical blend supports microbial balance in the gut, helps maintain oral health, and addresses issues like SIBO, candida, and biofilms. You'll hear why Biocidin stands apart from other antimicrobials—supporting the good guys while targeting the bad. Jared and Dr. Manske also discuss the importance of pairing Biocidin with binders and spore-based probiotics, how to introduce it safely (especially for sensitive individuals), and why it may be a game-changer for immune health, brain fog, and long-standing digestive complaints. They also explore the powerful benefits of Biocidin's oral care products and how the oral microbiome may play a more crucial role in systemic health than most people realize. Products:CellCore Biocidin ProductsCellCore BioToxin BinderVital 5 Precision Probiotic Vital SporesAdditional Information:#543: How to Choose the Right Binder for Detox, Parasites, Mold, and MetalsVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Matters Microbial #101: Electrifying News about Cable Bacteria July 25, 2025 Today, Dr. Nicole Geerlings from the University of Vienna in Austria joins the #QualityQuorum to discuss some of the wonderful work she and colleagues have carried out studying the wild, weird, and wonderful world of cable bacteria, which can conduct electricity over microbially enormous distances!  Definitely time for #OMG and #WTM! Host: Mark O. Martin Guest: Nicole Geerlings Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode This just became available:  a wonderful short introduction to day's topic, the cable bacteria, from Asimov Press.  It is an absolute must read for everyone interested. Here is a link to the Summer Science Program, a wonderful outreach program for high school juniors. An essay about Nobel Prize winning Albert Szent-Györgyi, who stated that life was a matter of electrons finding a place to rest.  Here is a short video introduction to his work. A video introduction to microbial metabolism. A video introduction to electron transport.  Remember that bacteria and archaea are VERY skilled at using different electron donors and acceptors than eukaryotic life. The really fun concept of the “Jagendorf Jump,” showing electron transport vs. pH in chloroplasts. An overview of the microbial fuel cell concept.  Here is a nice overview I highly recommend. A commercial source for you to build your own microbial fuel cell. A DIY approach to building a MFC.  An ESSENTIAL overview to the idea of electrons in microbial sediments. A review article about cable bacteria.  Here is another fine review. This is a third great introduction to cable bacteria. And here is a video overview.   An article by Dr. Geerlings and colleagues describing cable bacteria for new #Micronauts.  HIGHLY RECOMMENDED. An review of stable isotope probing in microbiology. Here is a video seminar using SIP in microbiology. An overview of Nano-SIMS and how it is used in microbiology.  Here is another review.   A deeply wonderful article by Dr. Geerlings and colleagues suggesting that inactive cells with the “microbial cable” are still conducting electrons! Dr. Geerlings postdoctoral scholar website. Links and References on Cable Bacteria from Dr. Geerlings: 1. Here is a website from the group of Prof. Dr. Filip Meysman from the University of Antwerp, which includes a great video on the electron conductivity of cable bacteria. 2. The first paper describing redox half-reactions separated by long-distance electron transport. Nielsen, L. P., Risgaard-Petersen, N., Fossing, H., Christensen, P. B., and Sayama, M. (2010). Electric currents couple spatially separated biogeochemical processes in marine sediment. Nature 463, 1071–1074. doi: 10.1038/nature08790 3. The paper describing the discovery of cable bacteria. Look into the supplemental material for the excellent experimental set-up to prove that the cable bacteria are the ones doing the long-distance electron transport. Pfeffer, C., Larsen, S., Song, J., Dong, M., Besenbacher, F., Meyer, R. L., et al. (2012). Filamentous bacteria transport electrons over centimetre distances. Nature 491, 218–221. Doi: 10.1038/nature11586 4. A paper that dives into the conductivity of the cable bacteria network and shows that these fibres can conduct electrons just as well as a copper wire. Meysman, F. J. R., Cornelissen, R., Trashin, S., Bonné, R., Martinez, S. H., van der Veen, J., et al. 2019. A highly conductive fibre network enables centimetre-scale electron transport in multicellular cable bacteria. Nat. Commun. 10:1–8. doi: 10.1038/s41467-019-12115-7 5. This paper describes how cable bacteria activity generates a layer of iron oxyhydroxides on the top of the sediment layer and how this delays the release of sulfide into the water column for several weeks in a seasonally hypoxic basin in the Netherlands. Seitaj, D., R. Schauer, F. Sulu-Gambari, et al. 2015. “Cable Bacteria Generate a Firewall Against Euxinia in Seasonally Hypoxic Basins.” Proceedings of the National Academy of Sciences of the United States of America 112: 13278–13283. 6. This paper describes how the catabolic division of labor is coupled to an anabolic division of labor where cells reducing oxygen cannot grow and therefore provide a “community service” for the rest of the filament. Nicole M. J. Geerlings, Cheryl Karman, Stanislav Trashin, Karel S. As, Michiel V. M. Kienhuis, Silvia Hidalgo-Martinez, Diana Vasquez-Cardenas, Henricus T.S. Boschker, Karolien de Wael, Jack J. Middelburg, Lubos Polerecky, and Filip J.R. Meysman. Division of labor and growth during electrical cooperation in multicellular cable bacteria. Proc. Natl. Acad. Sci. U.S.A. 117, 5478–5485. Doi: 10.1073/pnas.1916244117   Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Microbial fuel cells use bacteria to convert chemical energy stored in organic matter into electrical energy. This allows environmental engineers to produce sustainable energy while treating wastewater! In this episode of Let's Talk Chemistry, edited by Emma Stewart, hosts Jasmine Winter and John Strojny talk about our interview with Dr. Bruce Logan, Professor of Environmental Engineering and Director of the Institute of Energy and Environment at Penn State. From microbial fuel cells to marine snow, Dr. Bruce Logan shares his discoveries and insights on renewable energy and discusses the future of environmental engineering. We hope you enjoy!

Did you know your body is never truly sterile—even before you're born? From semen and placenta to umbilical cord blood, your microbial journey begins early on. And it doesn't stop there. The type of birth, nurturing, and how you explore the world as a child play a crucial role in shaping your unique microbiome. The introduction of solid foods, interactions with your environment, and social contact add even more layers of complexity. By adulthood, your gut microbiome reaches its peak flexibility and resilience—but its foundations are built much earlier in life.As a young child, you explore the world with your hands, mouth, and curiosity—interacting constantly with an invisible universe of microbes. However, science has only recently started to seriously explore the deep and complex relationships between children and microbes.One pioneering initiative is the Microbial Childhood Collaboratory—an international, interdisciplinary research group exploring the concept of the biosocial child: not merely as an individual, but as an ecological being, deeply entangled in microbial and biospheric communities that sustain life. One of their projects, Microbial Childhood: Restor(y)ing Daycare Ecologies, emerges from research and experimentation around the design of a microbial-friendly daycare in Tampere, Finland.The Collaboratory brings together community artists, environmental ecologists, sociologists, anthropologists, and early childhood education researchers—including Zsuzsa Millei, Professor of Early Childhood Education at Tampere University, who joins us in this episode.

This week on the podcast, Patrick and Tracy welcome Joan Slonczewski, author of Minds in Transit. About Minds in Transit: In the hundred-level city of Iridis, human lords recycle diamonds and emeralds down to the Underworld while sentient machines pilot lightcraft and perform surgeries. Microbial minds expand the brains of scientists and artists. The artist […] The post Episode 671-With Joan Slonczewski appeared first on The Functional Nerds.

For effective and long-lasting mold removal in the greater Tampa Bay region, contact the licensed professionals at TampaBayMold.net, and ask about their unique Antimicrobial Defense System. Go here for more information. TampaBayMold.net City: Tampa Address: 550 N. Reo St. Suite #300 Website: https://www.tampabaymold.net

TWiM explores the use of gas sensors and machine learning to identify microbes and antimicrobial resistance in clinical specimens, and how a harmful algal bloom species releases thiamin antivitamins to suppress competitors.   Become a patron of TWiM.   Links for this episode: Microbial and antimicrobial resistance diagnostics (Cell Biomaterials) Thiamin antivitamins suppress algal competitors (mBio) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv  

Matters Microbial #100: What's the Buzz on Phage Therapy for Honeybees? July 14, 2025 Today, Dr. Heather Hendrickson from the University of Canterbury in New Zealand joins the #QualityQuorum to discuss the research she and her team are conducting on bacteriophage therapy to protect vulnerable honeybees from bacterial infections. Host: Mark O. Martin Guest: Heather Hendrickson Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is the website for a former undergraduate research student of mine, Dr. Paula Welander, now a professor and administrator at Stanford University.  Yes, I am proud. Here is a link to another former undergraduate research student of mine, Dr. Krista Venecia Edmiston, now a professor at California Health Sciences University.  Yes, I am proud. A review on cell shape in bacteria. A review on the cytoskeleton of bacteria and archaea. I am a great admirer of Dr. John Roth, and his clearheaded and direct approach to microbial genetics.  Here is his academic website with many publications. An article about the causative agent of American Foulbrood, Paenibacillus larvae. An overview of American Foulbrood's impact on honeybees. The honeybee lifecycle. Beemites and honeybees. A video overview of bacteriophage therapy against bacterial diseases. An explainer of bacteriophage plaques. A video overview of lytic versus lysogenic bacteriophages. Dr. Graham Hatfull and his simply amazing SEAPHAGEs program, teaching so many people about isolating and studying bacteriophages. An article from Dr. Hendrickson's laboratory exploring cell shape in bacteria. An article from Dr. Hendrickson's laboratory explaining the importance of protecting honeybees from American Foulbrood, and the approach her laboratory uses. An article from Dr. Hendrickson's laboratory describing a community based approach to search for bacteriophages of Paenibacillus larvae. An article from Dr. Hendrickson's laboratory analyzing the types of Paenibacillus attacking bacteriophages isolated in New Zealand. An article from Dr. Hendrickson's laboratory describing an improved method for isolating bacteriophages. A truly great video from Dr. Hendrickson some years ago, explaining her research.  This is a “must see.” Dr. Hendrickson's faculty webpage. Dr. Hendrickson's informative research group website. This section of Dr. Hendrickson's research group website is devoted to outreach, and so very worth your time. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

What if we could grow nutritious, sustainable protein—not in months or weeks—but in just one day? This episode's guest is doing just that. Rather than going big with animal agriculture, MicroHarvest is going small with microbial agriculture.  A huge number of animals are used to feed both our pets and the animals we raise for food. Kate Bekers, the CEO and co-founder of MicroHarvest, is seeking to change that. She's running a fast-rising European biotech startup using fermentation to produce high-quality protein from microbes—in just 24 hours. Based in Hamburg and Lisbon, MicroHarvest is on a mission to reshape how the world thinks about protein production. Rather than growing plants or animals, they grow single-cell microbes in bioreactors, yielding a high-protein, micronutrient-rich ingredient that can be used in everything from animal feed and pet food to, eventually, human food. With 10 million euros raised and hopefully a new 30 million euro round on the horizon, their process is fast, efficient, and radically resource-light—requiring far less land, water, and energy than traditional agriculture. Already able to produce one ton of their product per day, MicroHarvest is proving that microbial protein isn't just a lab experiment—it's a scalable, real-world solution. In this episode, Kate shares what it takes to bring biotech innovation to market, and why she believes protein production should be faster, cleaner, and closer to the consumer. We talk about the company's entry into pet food and aquaculture, and what the future holds for sustainable protein made from the tiniest organisms on Earth. If you're curious about the future of food, circular economies, or how to build a business that's good for animals and the planet, this conversation is for you.

In this episode, we detail Small Intestinal Fungal Overgrowth (SIFO), with a focus on fungal biofilm formation and its role in promoting microbial persistence and evasion of host immune responses. We discuss the phenotypic plasticity of Candida species, as well as biofilm matrices adherent to the intestinal mucosa. We further highlight common symptoms of SIFO as well as the effects of hypochlorhydria, reduced pancreatic enzyme and bile output, impaired motility, diminished commensal bacterial populations, and weakened mucosal immunity.Topics: 1. Introduction- Focus on the gut mucosal barrier.- Emphasis on Small Intestinal Fungal Overgrowth (SIFO) and biofilms.2. Intestinal Barrier Anatomy- The mucosa: epithelium, lamina propria, and a thin band of smooth muscle.- The epithelial layer.- Covered by protective mucus composed of mucin glycoproteins secreted by goblet cells.- In the small intestine: less dense mucus.3. Epithelial Integrity- Tight junctions.- Paracellular barrier preventing uncontrolled antigen passage.4. Lamina Propria5. Overview of Small Intestinal Fungal Overgrowth (SIFO)- SIFO involves fungal overgrowth in the small intestine, commonly Candida species.- Small intestines: Low microbial density due to motility, gastric acid, bile acids, immune surveillance, and more.- Contributing factors: hypochlorhydria, impaired motility, reduced digestive enzymes, diminished competitive flora, lowered immunity, and more.6. Candida Pathogenicity- Candida exhibits phenotypic plasticity: yeast and hyphal forms.- Biofilm formation.7. Biofilm Formation- Biofilms are structured communities of microbes within a self-produced extracellular matrix.- Resistance to antimicrobials and immune defenses.- Can develop on intestinal mucosa and in various other regions.8. SIFO and SIBO Overlap- Root causes and overlap between SIFO and Small Intestinal Bacterial Overgrowth (SIBO).- Common symptoms.9. Gastric Acid in More Detail- Stomach epithelium includes mucous, parietal, chief, and enteroendocrine cells- Parietal cells secrete hydrochloric acid.- HCl denatures proteins and aids in inhibiting pathogens.- Hypochlorhydria: possible causes. 10. Downstream Effects of Low Acid11. Gut Motility in More Detail- Motility involves rhythmic smooth muscle contractions.- Enteric nervous system (ENS): myenteric and submucosal plexuses.- Dysautonomia and motility.12. SIFO Contributing Factors13. Candida Regulation- Candida generally remains in unicellular yeast form under homeostatic regulation.- Controlled by microbial competition, host defenses, antifungal peptides, and more.14. Role of Mucus and sIgA- Mucosal immunity (including sIgA) aids in regulating Candida populations.- Low sIgA levels (due to stress, immune suppression, dysbiosis,…) weaken defense 15. Conclusion- Mucosal barrier structure.- SIFO and Candida.- Biofilm formation, microbial persistence, and mucosal disruption.- SIFO and SIBO.- Multifactorial nature of fungal dysbiosis, types of biofilms, and small intestinal overgrowth.Thank you to our episode sponsor: 1. OmneDiem®'s Histamine Digest® and Histamine Digest® PureMAX 2. Histamine Digest® Histamine Complete with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Matters Microbial #99: Albert Kluyver—Microbial Unity and Diversity in Metabolism July 10, 2025 Today, Dr. Dianne Newman of Caltech joins the #QualityQuorum live at ASM Microbe in Los Angeles, to discuss the role that Albert Kluvyer played in helping microbial scientists to understand the unity and diversity to be found in microbial metabolism. Host: Mark O. Martin Guest: Dianne Newman Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A review article by Roberto Kolter about the history of microbiology. An overview of the “Delft School” of microbiology.  Here is another article on that topic. The 1924 article by Albert Kluyver that Dr. Newman references—very much worth you time. A video overview of microbial metabolism.  Here is a recent article on that topic. A short biography of Albert Kluyver. Here is another article on that topic. A wonderful 2023 video seminar by Dr. Newman exploring the unity and diversity of microbial metabolism.  Much recommended. Dr. Newman's faculty website. Dr. Newman's very impressive research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this episode of The Poultry Nutrition Blackbelt Podcast, Dr. Cangliang Shen from West Virginia University explores how microbial contamination in poultry poses emerging challenges for food safety. He discusses the use of surrogate bacteria, thermal processing techniques, and sanitation protocols in real-world poultry feed operations. Listen now on all major platforms!"We find that temperature up to 80°C can reach a three log reduction for the efficiency, which gives us hints for developing sanitation procedures and hazard plans for local industry facilities."Meet the guest: Dr. Cangliang Shen earned his Ph.D. in Meat Science and Food Safety from Colorado State University, with earlier training in Veterinary Medicine. He is currently a Professor and Extension Specialist at West Virginia University, focusing on improving poultry meat and feed safety through microbiological research and hazard planning.Click here to read the full research article!Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:04) Introduction(03:27) Current research focus(04:38) Temperature thresholds effectiveness(06:50) Ingredient impact on safety(09:44) Hazard planning insights(13:11) Future research directions(14:55) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like:* Kemin* Kerry- Poultry Science Association- Anitox- BASF

Are you struggling to find sustainable solutions for your crops in an ever-changing agricultural landscape?I sat down with Jessica Staha, CEO of LPC Naturals, to discuss the fascinating world of microbials in agriculture. With a background in molecular biology and genetics, Jessica brings a wealth of knowledge to the table, having worked in various industries before finding her passion in agricultural technology.We delved into the unique challenges faced by both indoor and outdoor farming, and how microbials can provide innovative solutions. Jessica explained how their proprietary isolate of Beauveria bassiana works as a plant stimulant, helping crops withstand various stresses. She emphasized the importance of educating farmers and growers about the benefits of microbials, as they offer a more holistic approach to plant health compared to traditional chemical solutions.Throughout our conversation, we touched on the evolving landscape of controlled environment agriculture, the impact of extreme weather on farming, and the potential for collaboration within the industry. Jessica shared insights on leadership in a startup environment and the importance of maintaining work-life balance in the fast-paced world of agricultural innovation.If you're curious about the future of farming and how microbials could revolutionize crop management, this episode is a must-listen. Tune in to gain valuable insights from an industry expert and discover how these tiny organisms could make a big difference in agriculture.Thanks to Our SponsorsCEA Summit East - https://indoor.ag/cea-summit-east-2025/Indoor AgCon - https://indoor.ag/Key Takeaways5:57 From corporate to entrepreneurship challenges11:47 LPC Naturals origin and microbial solutions17:57 Educating farmers on microbial benefits24:59 Preparing environments for microbial use30:20 Balancing entrepreneurship and personal well-being35:17 Collaboration opportunities in microbial researchTweetable Quotes"DNA is DNA is DNA. It doesn't matter the organism. And so again, it's this universal language that you can communicate with.""In a controlled sector, you're really pushing those plants to an extreme. Really fast cycle times, beautiful, consistent responses are needed. And then on top of it, packaging, handling, long shelf lives are needed.""As more chemicals are being pulled and aren't being allowed to be used, it's clear that more people are doing a better job at communicating the efficacy of microbials in agriculture and vertical spaces."Resources MentionedWebsite - https://lpcnaturals.com/LinkedIn - https://www.linkedin.com/in/jessica-stahaInstagram - https://www.instagram.com/primesuperiorgrow/Facebook - https://www.facebook.com/primesuperiorgrowYouTube - https://www.youtube.com/@primesuperiorgrowConnect With UsVFP LinkedIn - https://www.linkedin.com/company/verticalfarmingpodcastVFP Twitter -

Matters Microbial #98: Nesting Dolls of Endosymbiosis July 3, 2025 Today, Dr. John McCutcheon of Arizona State University joins the #QualityQuorum to discuss the work he and his research group do to investigate the strategies by which microbes become symbionts of other cells. After all, the mitochondria and chloroplasts of eukaryotic cells, including yours, were once bacteria! Host: Mark O. Martin Guest: John McCutcheon Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video about the symbiosis of Hydra virdissima, which captured my heart when I was young.  Look at those symbiotic algae!  Here is an overview of this topic. A video describing the Rhizobium – legume nitrogen fixing symbiosis in all of its glory—by my PhD advisor, the great Dr. Sharon Long.  Here is an overview of this topic.   An appreciation of Paul Buchner's very important book, “Endosymbiosis of Animals with Plant Microorganisms.” A wonderful review by Dr. McCutcheon on how symbioses form. A wonderful essay by Ed Yong about an event that made eukaryotic cells possible:  how bacteria became mitochondria. A story about an anaerobic protist that lost its mitochondria completely. A bacterial symbiont of mitochondria, the “midichlorian.” The recent discovery of a new integrated symbiont that has become an organelle, the nitrosome. The “X-bacteria” and amoebae story. A retrospective on endosymbiosis, and Paramecium based on Tracey Sonneborn's work. An essay on aphids and bacteria. An article on the Moranella/Tremblaya symbiosis. An article on “bacteria inside other bacteria” found in several symbioses, written by Dr.McCutcheon and colleagues. Genomic instability in bacterial endosymbionts. An article on cicadas and bacterial endosymbionts from Dr. McCutcheon and colleagues. An article on mealybugs and bacterial endosymbionts from Dr. McCutcheon and colleagues. Dr. McCutcheon's thoughts on his career path (so worth reading). The Center for Mechanisms of Evolution research institute in which Dr. McCutcheon works. Dr. McCutcheon's faculty website. Dr. McCutcheon's (and his research team's) wonderful research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

This e[pisode of SpaceTime is brought to you with the support of NordVPN, SpacTime's official VPN service. And have we got a great offer for you, with a 30 Day Money-Back guarantee! To check out the details vist nordvpn.com/stuartgary or use the coupon code STUARTGARY at checkout.In this episode of SpaceTime, we explore the latest discoveries and research that are reshaping our understanding of Mars and the effects of solar activity on planetary climates.Curiosity Rover's New Martian Rock SamplesNASA's Mars Curiosity rover has drilled into a new region of Martian rock, revealing intriguing features that may provide insights into whether the planet ever had conditions suitable for life. The rover's findings include unique boxwork patterns formed by groundwater, suggesting that even as Mars dried up, water was still present below the surface. As Curiosity ascends Mount Sharp, scientists are eager to understand the implications of these patterns and the mineral cements involved, which may hold clues to Mars' climatic history and the potential for ancient microbial life.Solar Flares and Weather PatternsA groundbreaking study published in the Astronomical Journal has uncovered a connection between solar flares and short-term changes in weather patterns on exoplanets. Researchers found that flares from a planet's host star can cause measurable climate shifts within days, highlighting the importance of solar activity in modulating atmospheric behavior. This research not only enhances our understanding of exoplanet habitability but also suggests that solar variability may influence weather systems on Earth, particularly in volatile regions.Nasa's In-Flight Imagery ProjectNASA's Scientifically Calibrated in Flight Imagery (SCIFLI) team is set to gather vital data during the reentry of a European aerospace company's demonstration capsule. Utilizing advanced instruments, including a spectrometer and high-definition telescope, SCIFLI aims to capture real-time performance data that will refine computational models for future space missions. This mission highlights the importance of empirical data in enhancing safety and performance for crewed and robotic space exploration.www.spacetimewithstuartgary.com✍️ Episode ReferencesAstronomical Journalhttps://iopscience.iop.org/journal/1538-3881NASA Curiosity Roverhttps://mars.nasa.gov/msl/NASA SCIFLI Teamhttps://www.nasa.gov/langley/scifliBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-space-astronomy--2458531/support.

In the wet and humid conditions of Tampa, mold seems like a never-ending battle, but TampaBayMold.net (813-548-4997) adds a new weapon to your arsenal with its unique microbial defense system. Go to https://www.tampabaymold.net for more information. TampaBayMold.net City: Tampa Address: 550 N. Reo St. Suite #300 Website: https://www.tampabaymold.net

Scientific Sense ® by Gill Eapen: Prof. David Pearce is Professor of Applied Sciences at Northumbria University. The underlying theme of his research is to use microbiology to understand Polar ecosystem function and the potential for shifts in biogeochemical activity that may result from environmental change.Please subscribe to this channel:https://www.youtube.com/c/ScientificSense?sub_confirmation=1

What is the microbiome? Where is it? Why is it so foundational to many areas of health? And how can we support it besides avoiding antibiotics and taking probiotics? In today's episode I answer these questions, plus talk about specific testing, the nuances of what makes up the microbiome besides bacteria, and the many ways we can help keep it healthy or repair damage. Plus! Top tips for picking probiotic supplements, herbs to work with, and foods (in addition to fermented vegetables) that support your microbiome.Mentioned in today's episode is Missing Microbes by Martin Blaster.The Family Herbalism program and the Community Herbalistprogram through Herba Remedium are now open for registration. Sign up early and get 10% off. Early bird pricing ends July 15th!The Herbal Collective is open tomorrow!!! Go to the website and check out your two options – will you join the lite Collective, or the full membership for just $9 a month? Either way you get access to all of my podcastepisodes organized by topic and all the downloadables I've offered to the public. In the full membership you will also get an exclusive herb walk series, weekly meetups, free access to classes I offer on my website, and starting next year, free monthly, live classes. Go check it out and jump into the Herbal Collective today!Monthly newsletters from yours truly are available with podcast updates, favorite resources, and other educational material. Visit www.laureltreewellnessllc.com and scroll down to the bottom of the front page to sign up!Also available on my website is all the information you need to schedule an appointment with me, and we can help you create a holistic wellness plan to work on your health goals.Thank you for listening!

In this encore episode, we detail the enteric nervous system and regulation of gastrointestinal motility. We discuss factors including dysautonomia, stress, microbial overgrowth, and more, with regards to potential effects upon gastrointestinal motility. We further detail symptoms of altered GI motility. Topics:1. Introduction to Gastrointestinal Motility- Orchestrated contraction of smooth muscles that propel contents along the digestive tract.  - Roles in mixing, absorption, and preventing bacterial overgrowth.- Disruptions in motility. 2. The Enteric Nervous System (ENS) and Its Role- Myenteric and submucosal plexus.- Coordinating contractions and relaxations for effective motility. - Mucosa includes epithelium, lamina propria, and muscle.  - Submucosa houses the submucosal plexus.  - Muscularis externa. - Inner circular and outer longitudinal muscle layers with the myenteric plexus in between.   3. The Role of Interstitial Cells of Cajal (ICCs)- Specialized pacemaker cells in muscular layers  - Generate slow-wave electrical activity to synchronize smooth muscle contractions  - Critical for peristalsis.- Work with neural inputs to fine-tune gut motility   4. Dysautonomia and Its Impact on Gut Motility- Dysfunction of the autonomic nervous system (ANS)  - Motility impacts- Microbial overgrowth, SIBO 5. Gastrointestinal Dysmotility- Neurological dysregulation - Structural abnormalities and smooth muscle dysfunction  - Hormonal imbalances - Microbial overgrowth - Autoimmunity  6. The HPA Axis- Hypothalamus, pituitary gland, adrenal glands  - Central to the stress response and interlinked with gut function  - The amygdala and PVN of the hypothalamus  - CRH stimulates ACTH, leading to cortisol release from adrenal glands   7. Cortisol and Gut Barrier Function- Cortisol is a glucocorticoid that modulates immune function and gut physiology  - Chronic cortisol exposure can impair tight junction (TJ) integrity  - Increases paracellular permeability and allows passage of antigens and endotoxins   8.Stress-Induced Changes in Gut Motility- Slow gastric motility - Increased colonic motility  9. Symptoms of GI Dysmotility10. Addressing Root Cause(s)Thank you to our episode sponsor:1. Shop ⁠⁠⁠⁠⁠⁠⁠⁠Fresh Press Farms⁠⁠⁠'⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Peach Cider Vinegar⁠⁠⁠⁠⁠ at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Matters Microbial #97: Microbes in the Air (Way) June 27, 2025 Today, Dr. Ari Kozik, Assistant Professor at the University of MIchigan joins the #QualityQuorum to discuss the work she and her research group do to investigate microbes living within the lung and their relationship to health as well as microbiology outreach and representation. Host: Mark O. Martin Guest: Ari Kozik Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A wonderful discussion of airway microbes. A thought provoking article about microbes in our breath! Geography of mouth to lung and relevance to health. Relevance and definition of the term “microaspiration.” Some general characteristics of anaerobic bacteria A commercial video explaining the basics of anaerobic chambers An article about the airway microbiome A video overview about biofilms Kombucha sculpture as discussed briefly. A relevant article from Dr. Kozik's and coworkers. A video from This Week in Virology including Dr. Kozik about representation in the microbial sciences (very important to watch). Dr. Kozik's important efforts in science outreach. Dr. Kozik's faculty website. Dr. Kozik's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

This episode was recorded at the 2025 Florida Ruminant Nutrition Symposium. Microbial protein has always been Dr. Frikins' main interest. It's the most important and consistent source of protein for the cow, with a very high amino acid content. Histidine is the only exception, but bypass protein sources high in histidine complement microbial protein well. Our assessment of microbial protein is all based on prediction models. In his presentation, Dr. Firkins talked about what we can do to have consistently high microbial protein production and how to make the best use of the models. He touched on starch and fat content as two areas of focus, emphasizing a balanced diet to achieve a balanced supply of microbial protein. (5:36)Dr. Firkins notes that about 90% of the bacteria in the rumen can't be cultured, and there is great diversity in the rumen. There's a core group of bacteria that almost every cow has that are really good at their job because they've been co-selected along with the cow for fiber digestion. The panel discusses how much the microbiome changes over time, host interactions with the microbial population, and inoculation of calves at birth and weaning. (8:47)Dr. De Souza and Dr. Faciola talk about starch associative effects and their impacts on fiber digestibility, how sugars impact the rumen and butyrate production, and the importance of butyrate in de novo milk fat synthesis. Dr. Frikins hypothesizes that when sugars improve fiber digestibility, the sugar stimulates how fiber digesters do their job. Some studies have shown an increase in rumen pH when sugars are supplemented, which may be part of the mechanism of improved fiber digestibility. However, he doesn't recommend using sugars when there is a lot of starch in the diet. (13:38)Dr. Faciola and Dr. Firkins discuss some of the finer points of the dietary starch and fiber digestibility relationship. What are you replacing when you add more starch? What is the proper amount of effective fiber in higher-starch diets? On the other hand, if you decrease starch a little bit, there might be more room for fat. Well-managed cows with adequate effective fiber can probably handle more starch. Dr. Firkins underlines that starch is more digestible than fiber and thus supports microbial protein, but an optimum level is desirable, perhaps 28-20%. (20:37)The panel talks about microbial growth efficiency and the energy-spilling mechanisms some bacteria have. Some models suggest that starch-digesting bacteria have higher maintenance energy requirements. The group then pivots to methane production and available feed additives marketed to reduce methane. Dr. Firkins notes that there is quite a bit of variability in the additives. He emphasizes that if we're using these products, we need to know and measure what's in them and have them be consistent. This is challenging due not only to variability in product, but also rumen adaptation. Dr. Firkins also reminds the audience that improving the cow's efficiency in general in a variety of ways will lead to a smaller environmental footprint. This can range from improving reproductive efficiency to understanding differences in the microbiome of cows who emit more or less methane and trying to shift microbial populations to those with lower emissions. (23:12)Dr. De Souza and Dr. Firkins discuss fatty acid supplementation and fiber digestion relationships. Dr. Firkins explains that in the microbiology literature, it's common to culture bacteria in a simple or complex medium, then add yeast culture. Interestingly, the yeast culture contains a lot of palmitic acid, which has been shown to improve fiber digestibility. He suggests the cell membrane of the bacteria is very critical. When fat supplementation depresses fiber digestibility, he suspects it's disrupting the bacterial membrane. Dr. De Souza recommends 1-2% palmitic acid in the diet for optimal results. (33:58)The panel touches on the importance and relevance of in vitro fermentation work, why histidine is the limiting amino acid in microbial protein, and Dr. Firkins' passion for protozoa. (43:08)Panelists share their take-home thoughts. (53:40)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

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In this encore episode, we detail the cellular make-up of the gastric lining, highlighting hydrochloric acid (HCl) secretion and its role in digestion, micronutrient absorption, and microbial defense. We discuss potential pathophysiological consequences of hypochlorhydria, including impaired digestive signaling, bacterial overgrowth in the small intestine (SIBO), and more. Lastly, we detail upstream microbial control, focusing on the influence of the oral microbiome and oral dysbiosis.Topics: 1. Introduction- Highlighting the stomach and hypochlorhydria / low stomach acid, as well as microbial balance, dysbiosis, and overgrowth.- Discussion of intestinal microbiome and oral microbiome. 2. Gastric Anatomy and Mucosal Layers- The stomach: cardia, fundus, body, pylorus.- The gastric mucosa: epithelial lining, lamina propria, muscularis mucosae.- The epithelial layer: mucous cells, parietal cells, chief cells, enteroendocrine cells.- Beneath the mucosa: submucosa and muscular layers that contribute to gastric motility, mechanical digestion, and more. 3. Mucous Cells - The surface epithelium and gastric pits.- Secretion of thick, viscous mucus.- Protecting the epithelium.- The mucus traps bicarbonate ions: neutral microenvironment that protects against acid-induced damage. 4. Parietal Cells and Gastric Acid Secretion- Secretion of hydrochloric acid (HCl): denatures dietary proteins, sterilizes ingested food.- Parietal cells produce intrinsic factor: binds vitamin B12 to facilitate absorption in the ileum. 5. Chief Cells and Pepsinogen- Secretion of pepsinogen: activated by low pH into the proteolytic enzyme pepsin.- Pepsin and protein digestion.- Release of gastric lipase. 6. Hydrochloric Acid: Digestive and Protective Roles- Immune defense.- Pepsinogen activation.- Adequate gastric acidity essential for properly acidified chyme.- Priming release of bile and pancreatic enzymes. 7. The Small Intestine, Stomach, and Microbial Regulation- The pyloric sphincter.- The stomach supports minimal microbial diversity.- Acidic barrier aids in limiting the entry of opportunistic microbes into the small intestine. 8. Hypochlorhydria, Low Stomach Acid- Hypochlorhydria can compromise one of the body's defense mechanisms.- Colonization of the small intestine.- Insufficient pepsinogen activation and possible protein digestion impairment.- Suboptimal chyme formation and downstream digestive capacity.- Possible symptoms of hypochlorhydria.- Possible impaired absorption of micronutrients including vitamin B12, iron, calcium, magnesium.- H. pylori infection, autoimmunity, aging. 9. The Oral Microbiome, Intestinal Microbiome, and Dysbiosis- Oral and environmental microbes.- Altered gastric pH, bile, digestive enzymes, and more.- The oral cavity as the gateway to the GI tract.- Oral microbial species.- Oral hygiene and oral microbiome health. 10. Conclusion- Root-cause approach.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Matters Microbial #96: Molecular Microbiology in High Schools June 19, 2025 Today, Bob Kuhn, biotechnology teacher at the Fulton County Schools Innovation Academy STEM high school in Alpharetta, Georgia joins the #QualityQuorum to discuss his strategies for teaching molecular microbiology skills and concepts to high school students — and why that matters. Host: Mark O. Martin Guest: Bob Kuhn Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An article on Mr. Kuhn's original microbiological interest:  salt marsh foraminifera. Another interest:  a video of the beautiful organism Volvox. An overview of the fantastic world of protists. A classroom CURE that Mr. Kuhn uses:  the Tiny Earth program. A classroom CURE that Mr. Kuhn uses:  the SEAPHAGES program. A classroom CURE that Mr. Kuhn uses:  the Evolving Stem program. A classroom CURE that Mr. Kuhn uses:  the Discover the Microbes Within program. Mr. Kuhn's classroom received help from the University of Georgia Microscopy Center. A video of the Wolbachia Project with which Mr. Kuhn has collaborated for years. An overview of wonderful and various isopods, including the “roly polies” used in some Wolbachia work. The Journal of Emerging Investigators, in which some of Mr. Kuhn's high school students have published. The LTEE program that studies evolution in E. coli.   The Experiment.com program that supported some of Mr. Kuhn's students. The very inspirational MEGAplate video that demonstrates how quickly antibiotic resistance can occur. Innovation Academy STEM program in Georgia, where Mr. Kuhn works with high school students. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #95: Bacteria and Aphids — A Symbiotic Story June 12, 2025 Today, Dr. Tory Hendry, Associate Professor of Microbiology at Cornell University, joins the #QualityQuorum to tell us about the relationship between plant munching aphids and fluorescent Pseudomonas . . . and why we should care. Host: Mark O. Martin Guests: Tory Hendry Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of siderophores in microorganisms. An essay about aphid life cycle and characteristics. An article describing parthenogenesis in aphids. An essay describing aphids and color vision. The agricultural costs of aphids as pests. An article describing aphids and one type of bacterial symbiont. An overview of microbes of the phyllosphere. An overview of quorum sensing. An overview of pyoverdin, a fluorescent siderophore.  An old essay I wrote for the Small Things Considered blog about semiochemicals, bacterial, and insect predation. A nice description of the work Dr. Hendry talked about during today's podcast.  The actual article by Dr. Hendry and collaborators. A preprint by Dr. Hendry's research group, following up on the above research.  Dr. Hendry's faculty website. Dr. Hendry's research group website (with SO MANY cool projects to think about, including the topic discussed today). Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

On this ID the Future from the archive, host Jonathan Witt speaks to molecular biologist and professor Dustin Van Hofwegen about his research into the engineered complexity in microbial life. Hofwegen shares his research on the famous decades-long E. coli evolution experiment conducted by Richard Lenski, which showed the sudden appearance of an ability to utilize citrate after many generations. However, Van Hofwegen's own experiments demonstrated that this "evolutionary innovation" actually points to the intelligent design built into living systems instead of an undirected process like natural selection. Source

Matters Microbial #94: One Health and Microbiomes Everywhere June 5, 2025 Today, Dr. Seth Bordenstein and Dr. Nichole Ginnan of Pennsylvania State University join the #QualityQuorum to tell us about their new publication linking One Health to the myriad microbiomes that exist all around us through the lens of the holobiome—and an opportunity to see the world in a different fashion. Host: Mark O. Martin Guests: Seth Bordenstein and Nichole Ginnan Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Michele Banks microbially themed art can found at her Etsy site.  Highly recommended! The paper under discussion today, with Dr. Ginnan as first author.  You will see that coauthors include Dr. Bordenstein, and two previous visitors to the #MattersMicrobial podcast!  Thank you Erika and Francisco. Dr. Bordenstein's first podcast with #MattersMicrobial for those who missed it. A review of the One Health concept. The One Health Microbiome Center at Penn State. A very clear overview of the holobiont concept and biology, authored by Dr. Bordenstein and colleagues. Another longer review on this topic. The faculty website for Dr. Ginnan. The faculty website for Dr. Bordenstein. The research website for Dr. Ginnan. The research website for Dr. Bordenstein. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Shining a Light on Microbial ‘Dark Matter' of the Oral MicrobiomeBy Spring Hatfield, RDH, BSPHOriginal article published on Today's RDH: https://www.todaysrdh.com/shining-a-light-on-microbial-dark-matter-of-the-oral-microbiome/Need CE? Start earning CE credits today at ⁠⁠⁠⁠⁠https://rdh.tv/ce⁠⁠⁠⁠⁠Get daily dental hygiene articles at ⁠⁠⁠⁠⁠https://www.todaysrdh.com⁠⁠⁠⁠⁠ Follow Today's RDH on Facebook: ⁠⁠⁠⁠⁠https://www.facebook.com/TodaysRDH/⁠⁠⁠⁠⁠Follow Kara RDH on Facebook: ⁠⁠⁠⁠⁠https://www.facebook.com/DentalHygieneKaraRDH/⁠⁠⁠⁠⁠Follow Kara RDH on Instagram: ⁠⁠⁠⁠⁠https://www.instagram.com/kara_rdh/

This episode was recorded in Reno, Nevada, during the 2025 Western Dairy Management Conference. The panel discusses their individual experiences with outbreaks in different states. Beth talks about her group's microbial surveillance technology they used to compare rectal swabs from positive and non-positive herds. They noted elevations in specific virulent E. coli, Salmonella spp., and Clostridium perfringens in the HPAI-positive herds. Enrique noted that in California, the outbreak began in the South Valley during periods of heat stress, which exacerbated symptoms. He also felt that some dairies panicked a little and moved cows too much, which did not help. In the North Valley, the outbreak happened in cooler weather, and dairies purposefully did not move cows out of their pens and provided supportive therapy within the pen. (5:25)Dr. Schcolnik emphasized making sure i's are dotted and t's are crossed in your nutrition program to help manage through an outbreak. The immune system is an obligate glucose utilizer, so energy is key, as are protein and trace minerals. He noted they also added binders to diets, and either probiotics or double doses of yeast to keep the rumen healthy. Decreasing intake is a big symptom, so he recommends vitamin B supplementation to stimulate appetite. (12:30)The panel discusses how the Texas and California outbreaks differed from one another, including heat stress, recovery in milk production after infection, bird migration and cattle movement. Enrique notes that in California, it seemed like transmission was going downwind. Animal movement, wild birds and milk trucks were also implicated. (14:31)Several companies are investing in vaccine development, but the virus mutation is a challenge. Dr. Spencer wonders if the vaccine will end up resembling the human flu vaccine where you hope to target the general structure of the virus to reduce impact. The panel talks about natural immunity and how cows will be impacted in the lactation after they were ill. Dr. Schcolnik has observed that a percentage of cows who were dry during the outbreak aren't performing as well after freshening. He hypothesizes this could be due to mammary cell death during infection, as the virus lyses the cell as it exits the cell. (24:41)The panel discusses practical recommendations for dairy producers to prepare for or help mitigate during an outbreak. Biosecurity is key. Vaccines are hopefully on the way, but until then, minimizing cattle movements within the herd, post-dipping cows as soon as possible after the machine falls off and minimizing splashing of milk are all good practices. The panel looks forward to more research about all the different ways the virus transmits. They're also eager to learn more about treatment plans and what has worked for different dairies regarding giving fluids, altering rations, boosting the immune system, managing co-infections and impacts on calves and heifers. (29:18)Lastly, panelists share their take-home thoughts. (37:33)Scott invites the audience to Bourbon and Brainiacs at ADSA in Louisville - a bourbon tasting with all your favorite professors! Sign up here: https://balchem.com/anh/bourbon/Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Endolith is a Denver-based biotech startup revolutionizing mining by leveraging microbes to sustainably extract copper and lithium from low-grade ores. Founded in 2023, the company employs custom-engineered microbial communities, adaptive biohatcheries, and real-time cloud-based monitoring to enhance mineral recovery while minimizing environmental impact. Endolith's innovations have demonstrated significant improvements in copper extraction, attracting partnerships with industry leaders like BHP and Rio Tinto. Their approach not only boosts efficiency but also reduces reliance on harmful chemicals, aligning mining practices with clean energy goals.–Dr. Liz Dennett is a technologist and entrepreneur with nearly two decades of experience in biotech and energy industries.Previously, she was the CTO of Cemvita, developing nature-inspired biosolutions for a carbon-neutral future.  Liz has held senior roles at Wood Mackenzie, AWS, Biota Technology, Hess Corporation, and the NASA Astrobiology Institute. She is also an advisory board member for the UW-Madison Dept. of Geoscience.  Liz holds a MS and PhD in geoscience and astrobiology from the University of Wisconsin-Madison–We talked about reasons for her purple hair, copper demand expected to double by 2050, specially evolved microbial communities combined with cloud computing to enhance copper recovery, relying on internal validation over external approval, and bad mining puns.--

Fermented foods offer surprising health benefits with science showing they can increase gut microbial diversity in ways other dietary interventions cannot.• Expert Elisa Caffrey clarifies what qualifies as fermented food: substrate + microbes + time• While touted as a source of probiotics, most fermented foods don't technically contain probiotics, which require specific strain characterization and known health benefits•Different types of fermentation are used in food production: lactic acid bacteria ferment carbohydrates in sauerkraut and yogurt; acetic acid bacteria oxidize ethanol into acetic acid in kombucha; and filamentous fungi such as Aspergillus oryzae and Rhizopus species are involved in the fermentation of miso and tempeh, respectively.• Fermented foods may benefit gut health through microbial derived metabolites rather than just the microbes in the food or beverage.• Consider starting with yogurt if you are a newcomer and have fun exploring kimchi, sauerkraut and other options for fermented food variety.• Most fermented foods are safe, though some considerations exist for those with histamine intolerance or sodium restrictions• Variety is key – consuming diverse fermented foods appears to help maximize potential benefits• The fermentation process may have mental health benefits beyond nutrition though more research is neededTry incorporating fermented foods gradually into your diet and experiment with different types to find what works for your body and taste preferences. Let us know what makes your taste buds (and gut) happy! This episode has been sponsored by Activia. Check out their Gut Health Tool Kit here and A Gut Friendly Meal plan here.References:Caffrey EB et al. Unpacking food fermentation: Clinically relevant tools for fermented food identification and consumptionGaudiest G et al. Microbial and metabolic characterization of organic artisanal sauerkraut fermentation and study of gut health-promoting properties of sauerkraut brineWastyk HC et al. Gut microbiota-targeted diets modulate human immune status (high fiber vs fermented food study)Nielson ES et al. Lacto-fermented sauerkraut improves symptoms in IBS patients independent of product pasteurisation - A pilot study  Learn more about Kate and Dr. Riehl:Website: www.katescarlata.com and www.drriehl.comInstagram: @katescarlata @drriehl and @theguthealthpodcastOrder Kate and Dr. Riehl's book, Mind Your Gut: The Science-Based, Whole-body Guide to Living Well with IBS. The information included in this podcast is not a substitute for professional medical advice, examination, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider before starting any new treatment or making changes to existing treatment.

In this episode, we detail the oral microbiome and its relationship with the intestinal microbiome, detailing the oral-gut microbiota axis. We discuss the stepwise development of oral biofilm, the transition from plaque to dental calculus, and potential systemic impacts of oral dysbiosis, while highlighting intestinal health and focusing on Fusobacterium nucleatum. We then detail possible symptoms of oral dysbiosis as well as testing modalities. Topics:1. Overview of the Oral Microbiome and the Oral-Gut Axis - The oral cavity and the gut: microbially dense sites. - These regions are anatomically distinct but connected and capable of influencing each other. - The oral microbiome: bacterial species, fungi, viruses, archaea, protozoa. - Microbial distribution is influenced by the topography and chemistry of various oral surfaces. 2. Oral Cavity Anatomy and Microenvironments - The oral cavity is divided into the vestibule and oral cavity proper. - Lined by oral mucosa, which varies in structure. - These anatomical variations create unique ecological niches that support different microbial populations. 3. Tooth Structure and Relevance to Microbial Colonization - Teeth are embedded in the alveolar processes of the maxilla and mandible. - Tooth structure. - Long-term microbial colonization and biofilm development. 4. Biofilm / Dental Plaque Development - Biofilm begins with the formation of the acquired pellicle.- Pioneer species secreting extracellular polymeric substances (EPS).- Secondary colonizers coaggregate.- Coaggregation is species-specific.- Example.- Aerobes can lower local oxygen levels, creating micro anaerobic niches that support obligate anaerobes. 5. Maturation of the Biofilm  - Biofilm composition shifting to anaerobic, proteolytic species such as P. gingivalis. - F. nucleatum: a bridge species. 6. Mineralization and Formation of Dental Calculus - Mineralization, calcium and phosphate deposition. - Dental calculus. - Can promote further accumulation and worsen inflammation. 7. Oral Dysbiosis  - An imbalance in the oral microbial community. - Potential signs and symptoms. - Halitosis, swollen or bleeding gums, tooth sensitivity, new cavities, dry mouth or altered taste, recurrent infections, coated tongue, plaque buildup near the gumline. 8. Oral-Gut Axis and Systemic Implications - Physical, chemical, biochemical, and immunological barriers aid in preventing oral bacteria from colonizing the gut. - Oral bacteria can potentially impact intestinal health. -  F. nucleatum and IBD. 9. Oral Microbiome Testing10. Multi-Factorial Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Matters Microbial #93: Preventing Antibiotic Resistance May 29, 2025 Today's episode was an in-person podcast at the University of Texas Austin!  Dr. Despoina Mavridou, Assistant Professor of Molecular Biosciences, joins the #QualityQuorum to discuss how her research group improves antibiotic effectiveness by impeding protein folding, and why this matters in the fight against antimicrobial resistance. Host: Mark O. Martin Guest: Despoina Mavridou Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to a wonderful video of the #LuxArt by UT-Austin students during my visit. Please give it watch and enjoy the creativity and positive #MicrobialPR. An effective TED talk by science journalist Maryn McKenna describing the threat of AMR in an accessible fashion. A CDC report on the growing threat of AMR. A review article about antibiotics. An overview of how bacteria become resistant to antibiotics.  A very recent review of the cell wall of bacteria—often the target of antibiotics. A video overview of beta-lactam antibiotics and resistance mechanisms. An overview of how protein folding is related to activity of proteins…including AMR gene products. A wonderful article by Dr. Mavridou and coworkers, describing how altering protein folding in bacteria can make them more vulnerable to antibiotics. A less technical version of the above article; well worth your reading. Dr. Mavridou's faculty website. Dr. Mavridou's research group website, which is most interesting. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this episode, Dr. Adam Rinde welcomes back microbiologist and PolyBio Research Foundation co-founder Dr. Amy Proal. Together, they unravel a framework for understanding chronic illnesses through the lens of persistent infections and their impact on mitochondria, immunity, and neurological health.Dr. Proal shares cutting-edge research linking pathogens like herpesviruses, cytomegalovirus, Epstein-Barr, and even latent parasites to conditions like Alzheimer's, long COVID, chronic fatigue syndrome, POTS, and more. Discover how stealth microbes can disrupt the vagus nerve, hijack mitochondrial energy systems, and weaken immune responses, setting the stage for a cascade of chronic dysfunctions.The conversation dives deep into the role of immune modulation, including promising findings around low-dose rapamycin and its potential to restore immune signaling and combat viral persistence. They also explore diet, metabolic interventions, and new clinical trials shaping the future of treatment.Whether you're a patient, practitioner, or curious mind, this episode offers profound insight into the evolving science of chronic illness and hope for emerging therapies.

Matters Microbial #92: Microbial Metabolism in Extreme Places May 22, 2025 Today, Dr. Valerie DeAnda Torres, Assistant Professor of Microbiology and Cell Science at the University of Florida (and National Geographic Explorer), joins the #QualityQuorum to tell us about the research her team does, studying the evolution of metabolic pathways in extreme environments . . . and why these are important to geochemical cycling. Host: Mark O. Martin Guest: Valerie DeAnda Torres Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The Etsy vendor making the beautiful microbial pins I have mentioned.  A link to Sebastian Cocobia's site where the beautiful E. coli strains I referenced can be obtained.  The beauty and mystery of Paenibacillus colonies. A video showing a colony of Myxococcus consuming a colony of E. coli. A fun video of tardigrades singing “Happy birthday” by a former undergraduate student of mine, Dr. Jake Shaffer. The National Geographic Explorer program, which includes Dr. DeAnda Torres.  The deep sea submersible Alvin, in which Dr. DeAnda Torres has dived!  An overview of methanogenesis, one of the pathways that Dr. DeAnda Torres' research group studies. A review of biogeochemical cycles in the deep ocean. The work of my former undergraduate research student, Dr. Paula Welander, on membrane biosignatures in ancient rocks. A recent review of the Asgard archaea, that may be our ancient ancestors. Some recent work by Dr. DeAnda Torres and collaborators on the Asgard archaea. One of the research cruises in which Dr. DeAnda Torres participated. During one cruise that included an Alvin dive to a hydrothermal vent, Dr. DeAnda Torres and scientists working with her described their work in this livestream partially in Spanish. Dr. DeAnda Torres will be part of some upcoming collaborative research cruises, seen here. Here is an article and video describing some of the collaborative work Dr. DeAnda Torres carries out, studying microbial breakdown of PFAS chemicals in marine sediment. A link to the faculty website of Dr. DeAnda Torres. A link to the research website of the DeAnda Torres group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

True health encompasses so much more than just diet and exercise. However, you don't need complicated routines, a lot of money, or elaborate gadgets to make a positive impact on your health. Some of the most powerful things you can do to improve your longevity, boost your immune system, and lower your stress have to do with simple behaviors and habits you can create in your home. Today, you're going to learn about the impactful role that community can have on your microbiome, your disease risk, and your overall health. On this episode of The Model Health Show, you're going to hear my conversation with the incredible Dr. Amy Shah for her podcast, Save Yourself. In this conversation, we discussed the importance of shared family meals, how to prioritize eating real food, and why your relationships are a key determinant of your health. This episode is packed with the science behind how cultivating healthy relationships can influence your microbiome, your sleep, your immune system, and so much more. You're also going to learn the top two most important things you can do to transform your health. I hope you enjoy my conversation with Dr. Amy Shah!  In this episode you'll discover:  The most important part about being human. (09:48) How eating with your family can impact your health. (12:22) Why being part of a community can improve your microbiome. (14:47) The health benefits of multi-generational living. (17:52) An interesting fact about humans, evolution, and menopause. (23:13) Why creating your own community can transform your life. (25:24) How sharing meals with your children can reduce their risk of obesity and disordered eating. (28:04) The connection between the time spent at a table and health outcomes. (33:45) What the #1 factor is that influences longevity is. (38:04) Which hormone is the antidote to stress. (39:27) Why personalization is the key to health. (41:22) The most powerful nutrition shift you can make. (41:44) How American children's diets have become inundated with ultra-processed food. (42:37) The #1 way to minimize the ultra-processed food in your diet. (45:50) What post-ingestive feedback is. (49:14) What sleep nutrients are. (54:41) How often you should aim to share a meal with others. (58:09)  Items mentioned in this episode include:  Beekeepersnaturals.com/model - Save 25% sitewide through May 27!  PaleoValley.com/model - Use code MODEL for 15% off! Save Yourself with Dr. Amy Shah - Subscribe to Dr. Amy Shah's podcast! Eat Smarter Family Cookbook - Transform the health, fitness, and connection of your entire family with the Eat Smarter Family Cookbook!  Be sure you are subscribed to this podcast to automatically receive your episodes:   Apple Podcasts Spotify Soundcloud Pandora YouTube   This episode of The Model Health Show is brought to you by Beekeeper's Naturals and Paleovalley. Reinvent your medicine cabinet for with clean, effective products powered by the beehive & backed by science. Shop the Memorial Day Sale now through May 27th and get 25% off sitewide at beekeepersnaturals.com/model. Use my code MODEL at PaleoValley.com/model to save 15% sitewide on nutrient dense snacks, superfood supplements, and more.   

Microbial forensics is a science that lets us trace killers and terrorists by the microscopic footprints they leave behind. From the landmark 1994 HIV murder case where viral genetics first convicted a doctor, to the chilling Amerithrax investigation after 9/11. You'll learn how microbes are rewriting crime solving while we explore true cases, cutting-edge research on skin microbiomes and microbial death clocks, and what the future holds when invisible evidence becomes undeniable.   TOPICS DISCUSSED IN THIS EPISODE: What skin microbiomes reveal about who touched what and when How microbes can be used to map the timeline of a crime scene Intelligence agencies using "microbial geolocation" to trace where you've been How microbial forensics was used to solve a murder and trace the post 9/11 Anthrax murders The future of turning invisible bacterial clues into courtroom evidence Why microbial forensics could reshape how we solve crime—and even prevent terrorism   Leave us a Review: https://www.reversablepod.com/review   Need help with your gut? Visit my website gutsolution.ca to join a program: Get help now   Contact us: reversablepod.com/tips    FIND ME ON SOCIAL MEDIA: Instagram  Facebook  YouTube        

Matters Microbial #91: You Are What Your Genes Feed Your Microbiome May 16, 2025 Today, Dr. Emily Davenport, Assistant Professor in the Department of Biology and Huck Institutes of the Life Sciences at Penn State University, joins the #QualityQuorum to tell us about the research her team does, studying how our own genes impact our microbiomes.   Host: Mark O. Martin Guest: Emily Davenport Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A description of GWAS (“Genome Wide Association Study”).  Here is an introductory video about the concept. An explainer on organoids. An essay about the diversity of the host microbiome (i.e. is there a “healthy” microbiome?). An article of the work of Dr. Sarkis Mazamian on how individual host genes and bacterial genes can impact the microbiome. A nice write up for Dr. Mazamian's work showing how host genes and bacterial genes can work together…or not. An oldish video of how the infant microbiome develops over time by Dr. Rob Knight's research group. An article on the same topic from Dr. Ruth Ley. An essay on the mucosal microbiota, rather than the fecal microbiome. An interesting member of the human microbiome, Akkermansia that might be related to obesity. Another interesting member of the human microbiome, Bifidobacterium, which appears to be associated with host lactose metabolism.  Yes, there is a Giant Microbes plush toy. An overview of the impact of host genetics on the microbiome by Dr. Davenport.  A definition of heritability. An overview of the Hutterites and how their study has advanced genetics. An explainer of the power of twin studies in genetics. A fascinating article about ancient dental plaque microbiome by Dr. Davenport and others. Dr. Davenport's faculty website. Dr. Davenport's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

This Podcast Extra episode is from John's Ask Me Anything webinar from April 14. Drawing from his extensive research and firsthand experience, John will provide insights and practical solutions to help growers achieve healthier, more resilient crops. In this discussion, the topics cover: Nutritional management with copper, nitrogen, potassium, and calcium prevents wheat and barley lodging better than PGRs.  Soil aeration and oxygen flow enhance paramagnetism more effectively than paramagnetic rock powders. Side-dressing potassium, like potassium nitrate, benefits soil biology more than broadcasting potash. Adequate calcium and boron levels, plus soil aeration, reduce clubroot in brassicas. Compost, low soil carbon, and lack of humic substances cause high chloride in plant sap, mitigated by humicarb. Selenium may influence fatty acid profiles and yield in forages, but its role in oil crops is unclear. Balancing potassium and calcium with manganese and boron ensures optimal plant health. Microbial activity and preventing soil drying enhance potassium availability in clay soils. Micropack offers higher performance than seaweed or fish-based foliar sprays for tropical fruit groves. Deeper earthworm presence reflects better soil aeration and structure, not necessarily overall soil health. Seed Flare may penetrate sunflower shells but is less effective on stone fruit, needing experimentation. BioCoat Gold is best as a seed treatment but can be applied in-furrow.  About John Kempf John Kempf is the founder of Advancing Eco Agriculture (AEA). A top expert in biological and regenerative farming, John founded AEA in 2006 to help fellow farmers by providing the education, tools, and strategies that will have a global effect on the food supply and those who grow it. Through intense study and the knowledge gleaned from many industry leaders, John is building a comprehensive systems-based approach to plant nutrition – a system solidly based on the sciences of plant physiology, mineral nutrition, and soil microbiology. Support For This Show & Helping You Grow Since 2006, AEA has been on a mission to help growers become more resilient, efficient, and profitable with regenerative agriculture.  AEA works directly with growers to apply its unique line of liquid mineral crop nutrition products and biological inoculants. Informed by cutting-edge plant and soil data-gathering techniques, AEA's science-based programs empower farm operations to meet the crop quality markers that matter the most. AEA has created real and lasting change on millions of acres with its products and data-driven services by working hand-in-hand with growers to produce healthier soil, stronger crops, and higher profits. Beyond working on the ground with growers, AEA leads in regenerative agriculture media and education, producing and distributing the popular and highly-regarded Regenerative Agriculture Podcast, inspiring webinars, and other educational content that serve as go-to resources for growers worldwide. Learn more about AEA's regenerative programs and products: https://www.advancingecoag.com

We're bringing this powerhouse episode back to your ears—because it's just that good. Microbiologist and gut health innovator Dr. Kiran Krishnan returns for what might be our most impactful conversation yet. Together, we explore why your gut microbiome is the ultimate predictor of resilience, longevity, and even how well you'll respond to illness.Kiran breaks down the staggering impact of microbial diversity, how modern life has wiped out essential strains, and why his team is resurrecting ancient microbes for the modern gut. We also get into what he actually takes when flying 400,000 miles a year, the truth about keto, and how poop (yep!) holds the key to personalized healing.It's science, inspiration, and a whole lot of fun—complete with a poop-testing parody of “Dick in a Box.” You'll walk away with five daily practices to boost gut diversity and a renewed belief in your body's natural brilliance.HIGHLIGHTS[3:42] - How the digital world is changing what we know and how we connect[6:10] - Building resilience vs. chasing perfection in health[8:24] - What centenarians around the world teach us about gut diversity[13:01] - Why your poop holds the answers: shape, frequency, and clues to dysfunction[16:28] - Microbial extinction and why we've lost two-thirds of our gut species[21:56] - What is MegaGenesis and how keystone strains are being brought back[23:54] - Why restrictive diets harm the gut—and what to do instead[28:49] - The new FXBiome test: better resolution, actionable insights[38:24] - Covid, long-haul illness, and the gut's predictive power[43:57] - 5 lifestyle upgrades for gut diversity: from fasting to forest walks[49:32] - Why your household shares microbes—and why dogs help[58:07] - Kiran's closing message: there's always hope when you start with the gutCONNECT WITH DR. KIRAN KRISHNAN + MICROBIOME LABSWebsite: microbiomelabs.comInstagram: @microbiomelabsUPGRADE YOUR WELLNESSBeam Minerals: http://beamminerals.com/beautifullybroken(Use Code: BEAUTIFULLYBROKEN for Discount)Silver Biotics Wound Healing Gel: https://bit.ly/3JnxyDD (30% off)(Use Code: BEAUTIFULLYBROKEN for Discount)StemRegen: https://www.stemregen.co/products/stemregen?_ef_transaction_id=&oid=1&affid=52Code: beautifullybrokenLightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794Code: beautifullybroken CONNECT WITH FREDDIE Check out my website and store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: (https://www.youtube.com/@BeautifullyBrokenWorld)

This episode of Space Nuts is brought you with the support of Saily. If you love travelling, you need Saily by your side. To find out more and get the special Space Nuts listener discount, visit www.saily.com/spacenutspace Nuts Episode 513: Microbial Life in Space, Titan's Secrets, and the Search for Intermediate Black HolesIn this engaging episode of Space Nuts, host Heidi Campo returns with astronomer Professor Fred Watson to explore the intriguing intersection of microbiology and space exploration. From the mapping of microbes aboard the Tiangong Space Station to the potential for life beneath the icy crust of Titan, and the latest discoveries about intermediate black holes, this episode is a cosmic journey filled with fascinating insights.Episode Highlights:- Microbial Mapping on Tiangong: Heidi and Fred discuss the China Space Station Habitation Area Microbiome Program (CHAMP) and its efforts to map the microbial life aboard the Tiangong Space Station. They explore the implications of a sterile environment in space and how it might affect astronauts' health upon their return to Earth.- Life on Titan: The conversation shifts to Titan, Saturn's largest moon, where researchers are investigating the possibility of life in its sub-ice ocean. Fred explains how organic nutrients from Titan's surface might migrate through its thick ice layer, and the challenges of sustaining microbial life in such a harsh environment.- Geothermal Activity and Microbial Life: The duo delves into the potential for geothermal activity on Titan and how it might support life. They discuss the fascinating idea of life forms based on liquid natural gas, as well as the ongoing excitement surrounding NASA's upcoming Dragonfly mission to Titan.- Intermediate Mass Black Holes: The episode concludes with a discussion on the search for intermediate mass black holes, particularly in globular clusters. Fred shares insights from recent research that suggests the existence of these elusive black holes, shedding light on their formation and significance in the universe.For more Space Nuts, including our continually updating newsfeed and to listen to all our episodes, visit our website. Follow us on social media at SpaceNutsPod on Facebook, X, YouTube Music Music, Tumblr, Instagram, and TikTok. We love engaging with our community, so be sure to drop us a message or comment on your favorite platform.If you'd like to help support Space Nuts and join our growing family of insiders for commercial-free episodes and more, visit spacenutspodcast.com/aboutStay curious, keep looking up, and join us next time for more stellar insights and cosmic wonders. Until then, clear skies and happy stargazing.(00:00) Welcome to Space Nuts with Heidi Campo and Fred Watson(01:40) Discussion on microbial mapping aboard the Tiangong Space Station(11:20) Exploring the potential for life on Titan(22:15) The implications of geothermal activity in Titan's ocean(30:00) New findings on intermediate mass black holes in globular clustersFor the commercial free versions of Space Nuts join us on Patreon, Supercast, Apple Podcasts or become a supporter here: https://www.spreaker.com/podcast/space-nuts-astronomy-insights-cosmic-discoveries--2631155/support.

In this episode of the Beet Podcast, Kevin sits down with Michael Key, the brains behind Impello Biosciences, to dive deep into the fascinating world of biostimulants and microbial magic for plant health. From boosting productivity to promoting plant resilience, Michael unpacks the science behind these powerful tools. Tune in to discover how to apply these game-changing principles to make your garden flourish!  Connect with Michael Key: Michael Key is co-founder and CEO of Impello Biosciences, a Colorado-based company specializing in plant biostimulants and microbial solutions for agriculture. With a background in horticulture from Colorado State University, Michael authored several patents related to beneficial microbes and biochemical tools that enhance plant health and productivity. He combines scientific innovation with practical solutions to empower growers and promote eco-conscious farming practices. Find more from Michael Key at his website: https://impellobio.com  Support The Beet: → Shop: https://growepic.co/shop  → Seeds: https://growepic.co/botanicalinterests  Learn More: → All Our Channels: https://growepic.co/youtube  → Blog: https://growepic.co/blog  → Podcast: https://growepic.co/podcasts  → Discord: https://growepic.co/discord  → Instagram: https://growepic.co/insta  → TikTok: https://growepic.co/tiktok  → Pinterest: https://growepic.co/pinterest  → Twitter: https://growepic.co/twitter  → Facebook: https://growepic.co/facebook  → Facebook Group: https://growepic.co/fbgroup  → Love our products? Become an Epic affiliate! https://growepic.co/3FjQXqV Learn more about your ad choices. Visit podcastchoices.com/adchoices