Podcasts about microbial

Matters Microbial #113: Microbes That Swim, Swarm, Stand Up—and ‘Walk' October 24, 2025 Today Dr. Joshua Shrout, Professor of Civil and Environmental Engineering and Earth Sciences at the University of Notre Dame joins the #QualityQuorum to discuss the work of his research team on sociomicrobiology. This includes how bacteria sense a surface, move together in groups, and communicate with one another.   Host: Mark O. Martin Guest: Joshua Shrout Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a wonderful video about the late great Dr. Esther Lederberg.  Here is another article on that same subject. Here is an article about prodigiosin synthesis and Serratia marcescens.   An introduction to the concept of sociomicrobiology. An overview of bacterial swarming.  Here is a wonderful swarming video. An overview of bacterial swimming in liquid. An article about group/social motility in Myxococcus. A fine video explaining the amazing bacterial flagellar motor. An article about Vibrio parahaemolyticus and swarming. An overview of quorum sensing. Bacteria cultivated in the laboratory undergo mutational changes during “domestication.”  Pigments produced by Pseudomonas, including pyoverdin and pyocyanin. An article from Dr. Shrout's laboratory group describing interactions between Pseudomonas and Enterococcus described in this episode. The Type IV pili-based motility system. An article from Dr. Shrout's laboratory describing how Pseudomonas can “walk” on one pole during swarming. Here is a video from Dr. Shrout's laboratory showing Pseudomonas “walking” on their poles. An overview video of the Shrout laboratory's research interests. Dr. Shrout's faculty website. Dr. Shrout's truly beautiful research website. There are wonderful microbial videos there.  Very much worth your time. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Squirrels are notorious for being somewhat anti-social creatures. A team of researchers is trying to understand how the animals share crucial microbes that keep them healthy. University of Arizona evolutionary biologist Lauren Petrullo discusses the behavior of squirrels that leads to microbial exchange. Lauren Petrullo spoke with Tim Swindle, professor emeritus of Planetary Science at the University of Arizona.

Today we're diving into the world of expression systems with Iskandar Dib, of Validogen and we'll explore the remarkable potential of Pichia pastoris, a methylotrophic yeast that's revolutionizing pharmaceutical protein production and beyond. From industrial enzymes to biomaterials, food, feed, and diagnostics, Pichia offers a reliable, scalable, and cost-efficient platform for recombinant protein expression. Iskandar explains how biotechs can unlock Pichia's full potential through Validogen's sophisticated tools and strategies, fine-tuning protein expression with innovative genetic approaches and robust screening systems to deliver unmatched yields and quality. 01:06               Why Pichia is often overlooked or underestimated03:29               The basics of Pichia pastoris05:25               How Pichia compares to microbial hosts like E.coli08:14               Key advantages over mammalian cell systems10:21               Pichia as a system for secreted production11:30               Pichia and post-translational modifications14:30               The challenges of working with Pichia16:25               Strain optimization and genetic engineering17:29               Meet Iskandar Dib and Validogen19:03               The UNLOCK PICHIA platform24:00               Real-world applications of Pichia pastoris in biopharma27:19               When Pichia outperforms expectations28:25               Adapting Pichia for emerging fields30:23               Advice for those considering Pichia pastoris for protein expression33:23               Learn more about ValidogenThis episode is sponsored by Validogen.Interested in being a sponsor of an episode of our podcast? Discover how you can get involved here! Stay updated by subscribing to our newsletterTo dive deeper into the topic: Pichia case studiesUnlocking Pichia for industry

This week on the Green Scene the amazing microbial world inside trees and how ants shape their colonies to prevent the spread of disease. All to discuss with Dr Ruth Freeman Director of Research for Society For Research Ireland.All with thanks to Repak.

Chapter 1 – Intertrigo: Prevention, Work-Up, and When (Not) to Use Antibiotics (00:11) John introduces the podcast episode and the hosts. (02:39) John welcomes Dr Laura Buckley (Senior Lecturer, Veterinary Dermatology, University of Liverpool) and asks what “brachycephalic” means and which breeds it covers. Laura explains shortened muzzles and broad, domed heads; the most extreme include French and British Bulldogs, Pugs and Boston Terriers, with Cavaliers, Chihuahuas and Dogue de Bordeaux also affected. (04:00) Sue notes their huge popularity in UK primary care. Laura adds that around 40% of her clinic can be French Bulldogs, with brachycephalics a very large overall share. (04:33) Sue asks which skin problems are most common. Laura explains that atopic dermatitis and otitis (externa/media) lead, with interdigital furunculosis also frequent. Cavaliers often show primary secretory otitis media. Skin-fold dermatitis (intertrigo) and muzzle furunculosis are common, and lesions can form over bony prominences where itchy dogs rub. (06:15) Sue asks what intertrigo is and why brachys get it. Laura explains shortened muzzles leave redundant skin that folds around eyes and muzzle, creating humid, low-airflow pockets that accumulate keratinous/sebaceous debris. Microbial overgrowth follows; bristly coats plus rubbing traumatises follicles and escalates inflammation. (08:06) Sue asks about prevention. Laura suggests daily fold hygiene from the start: clean away debris; consider antiseptic wipes (e.g., chlorhexidine) once or twice daily, and increase during flare-prone periods. (09:15) Sue highlights how early routines improve compliance and handling; Laura agrees it gives a “head start,” especially as atopy often appears within the first three years. (10:08) John asks how early disease presents and how to work it up. Laura explains earliest signs are diffuse erythema in the fold, then partial/complete alopecia, erosion/ulceration, crusting; severe untreated cases may progress to folliculitis and even deep pyoderma. (11:48) Sue asks about cytology. Laura explains it's pivotal: expect keratinous debris with cocci (staphylococci) or Malassezia in overgrowth; neutrophils with intracellular bacteria indicate infection and guide therapy. (12:57) John asks if systemic antibiotics are ever needed. Laura explains they're rarely indicated: most cases respond to topical antiseptics/antimicrobials plus strong anti-inflammatory control. Consider systemic antibiotics only for genuine deep, painful, draining pyoderma, immunosuppression, poor feasibility for topicals, or proven topical failure - always post culture & susceptibility. (15:47) John asks how she controls inflammation. Laura uses topical glucocorticoids (often in combination products). For severe inflammation, short anti-inflammatory courses of prednisolone (~0.5–1 mg/kg for a few days before tapering) can calm tissue so topicals can work. (16:48) Sue asks about long-term routines and when to consider surgery. Laura advises daily fold cleaning (once–twice daily) and twice-weekly topical anti-inflammatories (e.g., hydrocortisone aceponate or mometasone) with minimal systemic absorption; discuss surgery if medical care is impractical, or if maintenance fails with frequent relapses or recurrent infections. Chapter 2 – Viral Pigmented Plaques (VPP) (19:33) John moves to VPP and asks which brachy breeds are affected. Laura most often sees Pugs, plus Boston Terriers, Chihuahuas and French Bulldogs. (20:25) Sue asks what they look like. Laura describes numerous, heavily pigmented, slightly raised plaques that may begin flatter and become scaly, verruciform and hyperkeratotic over time. (22:00) Sue asks how to differentiate melanoma. Laura says biopsy/histopathology is the diagnostic choice; FNAs from plaques are often low-cellularity keratinocytes, whereas melanoma cytology differs. (23:43) John asks if plaques regress. Laura explains most persist or increase, likely due to a virus-specific, genetically influenced immunodeficiency in otherwise healthy, often young dogs. For treatment, Laura notes most are cosmetic, but very rarely plaques can transform to SCC, so monitoring matters. Limited numbers can be removed surgically or with laser; for numerous lesions consider systemic/medical options (e.g., azithromycin, interferon, retinoids, vitamin A, topical imiquimod) with variable success. (25:35) Sue summarises a primary-care approach: monitor unless numerous, pruritic, function-limiting or rapidly changing. Laura agrees; schedule regular reviews. Chapter 3 – Seasonal Flank Alopecia (SFA) (26:30) Sue introduces SFA and asks what it is and why it happens. Laura explains it's a localised cyclic follicular dysplasia linked to photoperiod and melatonin; predisposed breeds include Boxers, Affenpinschers, British Bulldogs, Staffies and Chihuahuas. (29:40) John asks about geography. Laura notes seasonality is more marked away from the equator where day-length swings are greater. Sue recalls light-box data suggesting equal photoperiod may prevent SFA; both agree the pattern fits a light/melatonin mechanism. (30:18) Sue contrasts the clinical picture with endocrine alopecia. Laura explains SFA shows sharply demarcated, bilateral flank patches (± hyperpigmentation). Endocrinopathies tend to be diffuse, affect coat quality and other sites (e.g., tail). (32:27) Sue asks differentials and work-up. Laura highlights hypothyroidism and Cushing's; use signalment and systemic signs, then haematology/biochemistry ± T4/TSH and targeted endocrine tests as indicated. (33:03) Sue asks about monitoring. Laura expects regrowth in spring within 1–4 months as day length rises, though a minority become permanently alopecic. (35:45) John asks about treatment. Laura reassures it's cosmetic once endocrinopathies are excluded; many owners opt to observe. For those wanting intervention, oral melatonin and increased light exposure are reasonable. (37:30) John thanks Laura and invites her for episode 2!

Joan Slonczewski is a microbiologist at Kenyon College and a science fiction writer who explores biology and space travel. Their books have twice earned the John W. Campbell Memorial Award for Best Science Fiction Novel: "A Door into Ocean" and "The Highest Frontier". Their latest novel is "Minds in Transit". With John W. Foster and Erik Zinser, they coauthor the textbook, Microbiology: An Evolving Science.In Sentientist Conversations we talk about the most important questions: “what's real?”, “who matters?” and "how can we make a better world?"Sentientism answers those questions with "evidence, reason & compassion for all sentient beings." The video of our conversation is ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here on YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.00:00 Clips00:51 Welcome03:10 Joan's Intro- Catholic Italian/Polish immigrant background "I project that into my thinking about the world... we're all immigrants one way or another"- Molecular microbiology at Kenyon College- Quakerism "quite consistent actually with the experimental world"- #scifi writing and Minds in Transit "the protagonist is an artist whose mind is filled with sentient microbes" & machine minds "she has to negotiate with her house as an intelligent entity"- The Mike Levin Sentientism episode & multiple levels of organisation, intelligence, analysis- "What is intelligence... on multiple levels"- Studying individual microbes / bacteria "organs for sensing and response"- "How do we know what they [the microbes] might be thinking or feeling"- "The microbial communities of our gut act as part of our brain... contribute to how our own brains think and feel"- Writing Brain Plague "That's my science fiction universe... but it's almost become real... we think of microbial communities as part of our brain"- Challenging our concept of intelligence: "What does it mean that a part of our intelligence and response is determined by a community of microscopic bacteria?"- Catholic parents "they did not practice religion at all but I think they inherited a strong sense of righteousness and justice from the Catholic tradition"- "A strong materialist tradition"... Father an IBM physicist, nominated for the Nobel prize re: work on magnetism- Mother a violin teacher- "I grew up with a sense of science and music... largely as a material worldview"- "Before I could read and write I knew I that I was going to be a scientist like my father"- Writing a first "scientific paper" in crayon- "There was never a question that I viewed the world in scientific terms... anything, to be true had to be recognised byexperiment"09:46 What's Real?27:00 What and Who Matters?01:14:57 A Better World?01:31:45: Follow Joan:- Minds in Transit at Bookshop.org- Joan's Home Page- Joan at Kenyon College- Joan on Wikipedia- Quakers in the UKAnd more... full show notes at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sentientism.info⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Sentientism is “Evidence, reason & compassion for all sentient beings.” More at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sentientism.info⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Join our⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠"I'm a Sentientist" wall⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ via⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ this simple form⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Everyone, Sentientist or not, is welcome in our ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠groups⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. The biggest so far is ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here on FaceBook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Come join us there!

Matters Microbial #112: Bacterial Size, Stress, and Antibiotic Resistance October 17, 2025 Today Dr. Petra Levin, the George and Irene Freiberg Professor of Biology at Washington University in St. Louis joins the #QualityQuorum to discuss her work with bacterial cell size, environmental stress on bacteria, and antibiotic resistance. Host: Mark O. Martin Guest: Petra Levin Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of the periplasm, found in Gram negative bacteria. An overview of beta-lactam antibiotics. The field of quantitative microbiology. An overview of B. subtilis.  An overview of E. coli.  An overview of Klebsiella.  The biography of Barbara McClintock, “A Feeling for the Organism.” A video explanation of the lac operon of E. coli. The LTEE program (Long Term Evolution Experiment) founded by Dr. Rich Lenski. The nomenclature of monoderm and diderm bacteria. A video explanation of peptidoglycan in bacteria. Penicillin binding proteins (PBP) and antibiotic resistance. A video about cell division in E. coli. A famous article coauthored by Dr. Elio Schaechter that describes cell growth and cell size in bacteria. A related article by Dr. Levin and colleagues. An overview of ESKAPE bacteria. An article from Dr. Levin's research group describing the relationship between pH and antibiotic resistance. An article about persister cells and their relevance to antibiotic resistance. Dr. Levin's faculty website. Dr. Levin's very interesting laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

SpaceX's Starship Flight 11: NASA spaceflight has reported that SpaceX is gearing up for Starship Flight 11, marking the final launch from Pad 1A in its current configuration. This mission will transition SpaceX to the advanced Block 3 designs, utilizing booster 152 and ship 38 to test engine redundancy and heat shield performance.Terraforming Mars Feasibility: A recent workshop summary suggests that advancements in launch costs, synthetic biology, and climate modeling have made the dream of terraforming Mars more feasible than ever. The proposed process includes warming the planet, introducing extremophiles, and eventually creating an oxygen-rich atmosphere for complex life.Discovery of Betel Buddy: Researchers have confirmed the existence of a companion star to Betelgeuse, affectionately named Betel Buddy. This discovery, utilizing advanced instruments like the Hubble Telescope, sheds light on the mysterious dimming cycles of Betelgeuse and challenges existing binary star formation theories.Microbial Resilience in Space: A groundbreaking study from RMIT University reveals that Bacillus subtilis spores can survive the extreme conditions of spaceflight, demonstrating resilience that could support astronaut health and sustainable life support systems on long-duration missions to the Moon and Mars.Mysterious Sounds in Space: The Daily Galaxy revisits the eerie knocking sounds reported by China's first astronaut, Jingle during his 2003 mission. These sounds, described as akin to a wooden hammer, have been echoed by other astronauts and remain an unsolved mystery in the realm of space exploration.For more cosmic updates, visit our website at astronomydaily.io. Join our community on social media by searching for #AstroDailyPod on Facebook, X, YouTubeMusic, TikTok, and our new Instagram account! Don't forget to subscribe to the podcast on Apple Podcasts, Spotify, iHeartRadio, or wherever you get your podcasts.Thank you for tuning in. This is Anna and Avery signing off. Until next time, keep looking up and exploring the wonders of our universe.✍️ Episode ReferencesStarship Flight 11 Details[NASA Spaceflight](https://www.nasaspaceflight.com/)Terraforming Mars Insights[Universe Today](https://www.universetoday.com/)Betel Buddy Discovery[Carnegie Mellon University](https://www.cmu.edu/)Microbial Resilience Study[RMIT University](https://www.rmit.edu.au/)Mysterious Sounds in Space[The Daily Galaxy](https://www.dailygalaxy.com/)Astronomy Daily[Astronomy Daily](http://www.astronomydaily.io/)Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-space-news-updates--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click Here

Matters Microbial #111: Shocking Tales of Metal-Loving Microbes October 10, 2025 Today Dr. Jeff Gralnick, Professor of the Department of Plant and Microbial Sciences at the University of Minnesota joins the #QualityQuorum to tell us a shocking story about how his research group studies the relationship between electrons, microbes, and metals.   Host: Mark O. Martin Guest: Jeff Gralnick Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An article about Nobel Prize winner Albert Szent-Györgyi. The Soudan Formation Iron Mine discussed during the podcast. An article on Banded Iron Formations. An article about the Oxygen Crisis early in Earth's history. An overview of the bacterium Shewanella. An overview of the bacterium Geobacter. An overview of microbial redox reactions. The “bacterial battery” we discussed: the Mudwatt. An article on benthic microbial fuel cells. An article on extracellular electron transfer by bacteria. The laboratory of Dr. Daniel Bond at the University of Minnesota, and colleague of Dr. Gralnick's. An essay on microbial nanowires. An essay on cable bacteria, which was the topic of #MattersMicrobial podcast #101 with Dr. Nicole Geerlings. The new field of electromicrobiology. The relationship between Shewanella and fish!  An article by Dr. Gralnick and colleagues on the Shewanella and fish (and bacteriophage) association. The article about Jon Beckwith (by Howard Shuman) discussed in the podcast:  “With Toothpicks and Logic.” Dr. Gralnick's faculty website. Dr. Gralnick's laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this Podcast Extra episode, John Kempf introduces Revenant Charge™, a new true-liquid biostimulant from AEA. Revenant Charge™ was developed to address the rising costs of soil health products for row crops while maintaining the powerful results growers have come to expect from AEA's Rejuvenate. Designed as a microbial accelerant, Revenant Charge™ stimulates soil biology and increases nutrient availability. In this episode, John discusses: The origin and purpose behind developing Revenant Charge™ and how it compares to Soil Primer and Rejuvenate. Early field trial data from Northeast Ohio, showing improved microbial activity and nutrient release. Insights from the Haney Soil Test results analyzed by Dr. Rick Haney, highlighting significant biological responses in diverse soils. The potential for Revenant Charge™ to improve nutrient cycling and soil disease suppression while reducing fertilizer dependence. Additional Resources To learn more about Revenant Charge™, please visit:  https://advancingecoag.com/product/revenant-charge/ About John Kempf John Kempf is the founder of Advancing Eco Agriculture (AEA). A top expert in biological and regenerative farming, John founded AEA in 2006 to help fellow farmers by providing the education, tools, and strategies that will have a global effect on the food supply and those who grow it. Through intense study and the knowledge gleaned from many industry leaders, John is building a comprehensive systems-based approach to plant nutrition – a system solidly based on the sciences of plant physiology, mineral nutrition, and soil microbiology. Support For This Show & Helping You Grow Since 2006, AEA has been on a mission to help growers become more resilient, efficient, and profitable with regenerative agriculture.  AEA works directly with growers to apply its unique line of liquid mineral crop nutrition products and biological inoculants. Informed by cutting-edge plant and soil data-gathering techniques, AEA's science-based programs empower farm operations to meet the crop quality markers that matter the most. AEA has created real and lasting change on millions of acres with its products and data-driven services by working hand-in-hand with growers to produce healthier soil, stronger crops, and higher profits. Beyond working on the ground with growers, AEA leads in regenerative agriculture media and education, producing and distributing the popular and highly-regarded Regenerative Agriculture Podcast, inspiring webinars, and other educational content that serve as go-to resources for growers worldwide. Learn more about AEA's regenerative programs and products: https://www.advancingecoag.com  

In This Podcast: We chat with Melissa Booth, a microbiologist and creator of the course 'The Hidden Powers of Microbes.' Melissa speaks about her journey from Oklahoma's semi-arid deserts to her passion for research. Initially interested in becoming a physician, her path changed after engaging in research on HIV/AIDS. She eventually pursued a master's in microbiology, leading her to study marine microbes and their responses to environmental cues. Melissa discusses the vital role microbes play in ecosystems, particularly in soil health, and how human actions impact these microbial systems. She also highlights the symbiotic relationships between microbes and plants, their influence on plant health, and the benefits of composting for soil. Melissa shares insights on her course through The Great Courses, which covers the significance of microbes in various aspects of life. Finally, she emphasizes the importance of curiosity, resilience in the face of scientific failure, and reconnecting with nature.Our Guest:  Melissa is a microbiologist, science communicator and creator of the course, the Hidden Powers of Microbes. She helps audiences uncover the surprising roles microbes play in everything from food and health to sustainability and climate resilience, bridging science and society with clarity, curiosity, and inspiration.Melissa's Book - I Contain Multitudes, by Ed YongContact Melissa and get her course -  TheScienceCommunicator.com Visit UrbanFarm.org/Microbes for the show notes and links on this episode! Need a little bit of advice or just a feedback on your design for your yard or garden?The Urban Farm Team is offering consults over the phone or zoom. Get the benefits of a personalized garden and yard space analysis without the cost of trip charges. You can chat with Greg, Janis or Ray to get permaculture based feedback.Click HERE to learn more!Become an Urban Farm Patron and listen to more than 900 episodes of the Urban Farm Podcast without ads. Click HERE to learn more.*Disclosure: Some of the links in our podcast show notes and blog posts are affiliate links and if you go through them to make a purchase, we will earn a nominal commission at no cost to you. We offer links to items recommended by our podcast guests and guest writers as a service to our audience and these items are not selected because of the commission we receive from your purchases. We know the decision is yours, and whether you decide to buy something is completely up to you.

In this episode of SpaceTime, we delve into the intriguing potential for life on the dwarf planet Ceres, explore NASA's latest mission to study the heliosphere, and celebrate the achievements of the University of Melbourne's Spirit Nanosat.Ceres: A Potentially Habitable World?Recent research published in Science Advances suggests that Ceres, currently a frigid and frozen world, may have once harboured conditions suitable for life. By modelling the planet's thermal and chemical history, scientists propose that Ceres could have sustained a long-lasting energy source, allowing for microbial metabolism. While there's no direct evidence of life, the findings indicate that Ceres had the necessary ingredients—water, carbon, and chemical energy—that could have supported single-celled organisms in its ancient past.Nasa's New Heliospheric MissionNASA has launched the Interstellar Mapping and Acceleration Probe (IMAP) to investigate the heliosphere, the magnetic bubble surrounding our solar system. This mission aims to enhance our understanding of solar wind and its interactions with interstellar particles, which are crucial for assessing space weather impacts on Earth. IMAP will operate alongside the Carruthers Geocorona Observatory and NOAA's Swifo L1 spacecraft, contributing to a comprehensive study of our solar environment.Spirit Nanosat's Milestone AchievementThe University of Melbourne's Spirit nanosatellite has successfully completed its initial mission phase, deploying its thermal management system and taking a selfie in space. Launched in December 2023, Spirit is equipped with a miniaturised gamma-ray detector to search for gamma-ray bursts, marking a significant advancement in small satellite technology and scientific exploration.www.spacetimewithstuartgary.com✍️ Episode ReferencesScience Advanceshttps://www.science.org/journal/sciadvNASA IMAP Missionhttps://www.nasa.gov/imapUniversity of Melbourne Spirit Nanosatellitehttps://www.unimelb.edu.au/Become a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.Ceres: A Potentially Habitable World?NASA's New Heliospheric MissionSpirit Nanosat's Milestone Achievement(00:00) New study claims the dwarf planet Ceres could once have been habitable enough for life(05:14) The Interstellar Mapping and Acceleration Probe will study the heliosphere(15:58) New study finds tropical fish are colonising new habitats because of ocean warming(18:07) Khloe Kardashian reportedly claims she's seen UFOs and experienced paranormal activity

Matters Microbial #110: Enumerating the Microbiome October 3, 2025 Today Dr. Sean Gibbons, Associate Professor at the Institute for Systems Biology, returns to the #QualityQuorum to tell us about how he and his colleagues are able to listen very carefully to the microbiome to uncover important hints about health. Host: Mark O. Martin Guest: Sean Gibbons Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is the article from Dr. Norm Pace and coworkers on the showerhead microbiome referenced in the podcast. Here is a nonspecialist summary of Dr. Pace's work on the showerhead microbiome and mycobacteria. Here is a link to a prior episode of this podcast with Dr. Ameet Pinto on microbiology of the water supply. Here is Dr. Gibbon's earlier visit to this podcast. An overview of the difference between microbiome and microbiota. An article about the “misnumbering” of the number of microbial to human cells in people.  Here is a nonspecialist summary. An overview of metagenomics. An overview of qPCR. An overview of flow cytometry. Plato's Allegory of the Cave, discussed in this podcast. A cautionary tale about determining a cancer microbiome, as discussed in this podcast. An article by Dr. Gibbons and colleagues described in this podcast about how to estimate microbial biomass directly. An article by Dr. Gibbons and colleagues described in this podcast about how to estimate microbial growth rates in the human gut using metagenomics. An article by Dr. Gibbons and colleagues described in this podcast about how to use metagenomics to determine dietary habits. The website for Dr. Gibbon's research group. The faculty website for Dr. Gibbons at ISB. Courses on microbiome sciences online at ISB. The website for Institute for Systems Biology. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Matters Microbial #109: Bat-Crazy About Rabies September 26, 2025 In honor of World Rabies Day, Dr. Rodney Rohde, Regents Professor at Texas State University,  joins the #QualityQuorum to discuss rabies and some of the strategies used to limit the influence of that devastating viral disease. Host: Mark O. Martin Guest: Rodney Rohde Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of rabies from the CDC. A historical overview of rabies and Louis Pasteur. The global impact of rabies. Bats and rabies. A podcast exploring rabies and myths about vampires and werewolves. A wonderful video about rabies SO worth your time. A video with three physicians about rabies. A detailed review of rabies and the rabies virus. The lifecycle of the rabies virus. Various tests for rabies. The vaccines for rabies. Rabies research at the CDC. Use of an oral rabies vaccine to eliminate epizootic rabies in coyotes and gray foxes in Texas. Information about World Rabies Day. The Contagion Live website, including podcasts by Dr. Rohde. A video from Dr. Rohde about medical laboratory science. A video from Dr. Rohde about rabies. Dr. Rohde's biography from the American Society for Microbiology. Dr. Rohde's faculty website. Dr. Rohde's personal website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

This episode features Dr. Marjon de Vos PhD from the University of Groningen (the Netherlands) speaking about microbial ecology and evolution, and in particular how these affect antimicrobial resistance. She studies the urobiome as well as the factors that contribute to urinary tract infections and successful treatment of these infections with antibiotics. Her lab combines molecular biology techniques with phenotypic and growth measurements, as well as computational modeling. She has found evidence of microbial interactions mediating evolutionary potential of microorganisms – for example, in vitro experiments showed that in the presence of Enterococcus, E. coli speeds up its rate of developing antimicrobial resistance. Thus, interactions within the bacterial ecosystem may affect pathogens' sensitivity to antimicrobials. Prebiotics are a potential intervention: if bacteria that make a pathogen more susceptible to antimicrobials are already present in the urobiome, their numbers could be enhanced. Probiotics are another possibility. From a One Health perspective, such approaches are important to explore because they support antimicrobial stewardship and help maintain control of antimicrobials in the environment overall. Episode abbreviations and links: Preprint describing pathogens' differing rates and evolutionary trajectories towards antibiotic resistance based on other microbes present: Microbial interactions affect the tempo and mode of antibiotic resistance evolution Paper describing ecological interactions between different bacterial species in urinary tract infections: Interaction networks, ecological stability, and collective antibiotic tolerance in polymicrobial infections Research showing how 5 different bacteria affect the conjugation efficiency of E. coli: Community context influences the conjugation efficiency of Escherichia coli  About Dr. Marjon de Vos PhD: We investigate ecological and evolutionary processes in microbial communities, with a focus on infectious contexts. Our goal is to unravel the genotype–phenotype–fitness relationships within (evolving) communities and to identify the ecological factors that drive microbial evolution. To achieve this, we combine molecular biology techniques with phenotypic and growth measurements, as well as computational modeling. Our research places special emphasis on the urobiome and urinary tract infections in postmenopausal women, as well as on sepsis. By uncovering the fundamental ecological and evolutionary dynamics of microbial communities in infectious diseases, we aim to contribute to the development of strategies that alleviate infections and help curb the emergence and spread of antibiotic resistance.

In this episode of The Dairy Nutrition Blackbelt Podcast, Richard Breunig, founder and owner of Priority IAC, shares his innovative perspective on integrating microbiology with dairy cattle nutrition. He discusses the role of specific bacterial strains in rumen fermentation, why acidosis should be addressed through microbial balance, and how rethinking common practices like negative DCAD and sodium bicarbonate can improve herd performance. Listen now on all major platforms!"Microbiology comes first, and nutrition follows; the organisms must be in place before anything else can work."Meet the guest: Richard Breunig, founder, president, and owner of Priority IAC, began his career on a Wisconsin dairy farm, gaining hands-on experience that shaped his focus on microbiology and nutrition. With a background in herd development and microbial application, Richard now leads innovations that improve dairy cattle health through specific bacterial strains.Liked this one? Don't stop now — Here's what we think you'll love!What will you learn: (00:00) Highlight(01:25) Introduction(01:05) Guest background(04:49) Microbiology X nutrition(09:21) Rethinking sodium bicarbonate(10:05) Rethinking DCAD(11:50) Microbial balance matters(19:25) Closing thoughtsThe Dairy Nutrition Blackbelt Podcast is trusted and supported by the innovative companies:* Priority IAC* Afimilk* Adisseo* Kemin- Zinpro- Virtus Nutrition

R-Soil REWIND - listen Dr. James F. White's talk from R-Soil 2024!! Watch the Full Presentation on Youtube: https://youtu.be/QZ-3ZXeujFU Dr. White will be joining us AGAIN this year!! Join Us For The FREE 5-Day Conference Focused On #SOIL!! www.R-Soil.com 30+ Speakers, Panels, Q&A, & GIVEAWAYS!!

Matters Microbial #108: Neanderthal Oral Health, Ancient Bacteria and DNA September 19, 2025 Today, Dr. Laura Weyrich, Associate Professor of Anthropology at Pennsylvania State University,  joins the #QualityQuorum to discuss the paleo oral microbiome! We will learn if our ancestors had the same kind of resident microbes as we do. In addition, we will learn about ancient DNA and what it can tell us. Host: Mark O. Martin Guest: Laura Weyrich Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An obituary for my late and much missed microbiologist friend, Dr. Kimberly Walker. A link to Episode #9 of #MattersMicrobial, with Sebastian Cocioba.  The ethics of collecting samples from deceased humans, both ancient and modern. An overview of the efforts to study ancient DNA.  Here is another review on that topic. The importance of proper controls for the study of low DNA abundance samples—the famous “kitome” often observed.  Here is an article by Dr. Weyrich and colleagues on this topic, as well. A recent article using human bones to detect Yersinia pestis, the causative agent of plague.  An overview of the oral microbiome. An article describing how dental calculus can be used to recover ancient DNA. An article by Dr. Weyrich and colleagues describing the human oral microbiome pre and post Industrial Revolution in Great Britain. A video describing our Neanderthal ancestors. An article by Dr. Weyrich and colleagues describing the Neanderthal oral microbiome and related issues. A fine video by Dr. Weyrich describing her research program. Dr. Weyrich's faculty website. Dr. Weyrich's research team website (SO INTERESTING). Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this episode of SpaceTime, we dive into groundbreaking discoveries on Mars, the intriguing atmosphere of Makemake, and the awe-inspiring total lunar eclipse that captivated millions.Potential Biosignatures on MarsNASA scientists have revealed that samples collected by the Perseverance rover from Jezero Crater may hold the best chance yet of uncovering evidence of past microbial life. The samples, taken from the rock formation known as Chiava Falls, exhibit characteristics that could indicate potential biosignatures. These findings suggest that Mars may have been habitable for longer than previously thought, challenging earlier assumptions about the planet's history.Atmosphere Discovered on MakemakeIn a remarkable discovery, astronomers have detected indications of a methane gas atmosphere on the distant dwarf planet Makemake. This finding, made using NASA's Webb Space Telescope, suggests the presence of a tenuous atmosphere or possibly cryovolcanic activity. Makemake, which resides in the Kuiper Belt, is now only the second known trans-Neptunian object, after Pluto, to have confirmed gaseous presence, revealing its dynamic nature and potential for active geology.Total Lunar EclipseA stunning total lunar eclipse has mesmerised observers across Australia, Europe, Africa, and Asia. This celestial event transformed the full moon into a blood-red spectacle as Earth's shadow obscured it. The eclipse lasted over five hours, showcasing the beauty of orbital mechanics and providing a thrilling experience for stargazers.www.spacetimewithstuartgary.com✍️ Episode ReferencesNaturehttps://www.nature.com/Astrophysical Journal Lettershttps://iopscience.iop.org/journal/2041-8205Become a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-space-astronomy--2458531/support.Potential Biosignatures on MarsAtmosphere Discovered on MakemakeTotal Lunar Eclipse

Matters Microbial #107: Listeria Sprouting Hysteria? September 11, 2025 Today, Dr. Lisa Gorski, a microbiologist and food safety consultant recently retired from the US Department of Agriculture, Agricultural Research Service, joins the #QualityQuorum to discuss the facts about the disease causing bacterium named Listeria. We will learn about the organism, the disease listeriosis, and food safety. Host: Mark O. Martin Guest: Lisa Gorski Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A description of the ice nucleation phenomenon carried out by many bacteria. An out of print book by Dr. Jo Handelsman that explained the ice nucleation experiment I often use when I teach. An overview of ice nucleation protein. A very nice video demonstration of ice nucleation activity I created many years ago with Puget Sound students. The relationship between ice nucleation protein and the commercial substance “SnowMax.” Information from the Centers for Disease Control on Listeria.  A description of listeriosis, caused by Listeria. A cute plush toy depicting Listeria, by the Giant Microbes company. A recent review article on Listeria and listeriosis. A video depicting “actin rockets” allowing Listeria to move within eukaryotic cells. A review article on actin-related motility of intracellular bacteria. A description of a recent Listeria outbreak. Advice for consumers regarding avoiding listeriosis.   The United States Department of Agriculture group on food safety and surveillance.  Articles by Dr. Gorski and colleagues on topics under discussion today. Dr. Gorski's LinkedIn profile. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Perseverance Rover's Potential Evidence of Life on Mars: NASA's Perseverance rover has uncovered what could be the strongest evidence yet for microbial life on Mars. The discovery of "leopard spots" on a rock in the Bright Jingle Formation contains organic carbon-rich material, clay minerals, and iron sulfide minerals that suggest biological processes akin to those of Earth microbes. While skepticism remains, the analysis indicates that these findings are most likely biological in origin, pending further examination through the Mars Sample Return mission.Risks of Asteroid Deflection Missions: A new study reveals that asteroid deflection missions might inadvertently increase the risk of Earth impacts. Researchers found that improper deflection could steer asteroids into gravitational keyholes, leading them onto collision courses with Earth. Sophisticated planning and probability maps are essential for safely redirecting asteroids, highlighting the complexity of such missions.James Webb Telescope's Massive Stellar Jet Discovery: The James Webb Space Telescope has captured astonishing images of an eight-light-year-long stellar jet originating from a massive protostar in the Sharpless 2284 Nebula. This discovery provides insights into the formation of massive stars and the dynamics of stellar jets, which scale with stellar mass.Pentagon's New Missile Defense Satellites: The Pentagon has launched 21 satellites for a new missile defense constellation, part of a plan to deploy 154 satellites in low Earth orbit. This innovative approach reduces costs significantly and enhances capabilities to detect modern threats like hypersonic weapons, marking a shift in military satellite economics.Nasa's Creative Helicopter Training: NASA has introduced a helicopter flight training course in the Colorado mountains to simulate lunar landing conditions for the Artemis missions. This hands-on training focuses on crew coordination and communication, preparing astronauts for the challenges of landing on the Moon amidst difficult terrain and lunar dust.Gaia Mission's Stellar Discoveries: The European Space Agency's Gaia mission has revealed complex star formation processes, identifying massive stellar streams in our galaxy. This groundbreaking data challenges previous notions of star formation, showing that it occurs in interconnected cascades triggered by supernovae, providing a deeper understanding of our galactic history.Artemis Gateway Updates: NASA has shared new details about the Gateway Lunar Space Station, which will serve as a hub for lunar missions and potentially a refueling stop for Mars expeditions. This initiative emphasizes international cooperation and in situ resource utilization, paving the way for humanity's expansion into the solar system.For more cosmic updates, visit our website at astronomydaily.io. Join our community on social media by searching for #AstroDailyPod on Facebook, X, YouTubeMusic Music, TikTok, and our new Instagram account! Don't forget to subscribe to the podcast on Apple Podcasts, Spotify, iHeartRadio, or wherever you get your podcasts.Thank you for tuning in. This is Anna and Avery signing off. Until next time, keep looking up and exploring the wonders of our universe.✍️ Episode ReferencesPerseverance Rover Findings[NASA](https://www.nasa.gov/)Asteroid Deflection Research[Nature](https://www.nature.com/)James Webb Telescope Discoveries[NASA](https://www.nasa.gov/)Pentagon Missile Defense Satellites[Department of Defense](https://www.defense.gov/)NASA Helicopter Training[NASA](https://www.nasa.gov/)Gaia Mission Updates[ESA](https://www.esa.int/)Artemis Gateway Information[NASA](https://www.nasa.gov/)Astronomy Daily[Astronomy Daily](http://www.astronomydaily.io/)Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-space-news-updates--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click Here

Episode Highlights With HannahHannah calls herself a farmer of microbes and she sees fermentation as a sacred practiceThe resurgence of ancient wisdom though regenerative farmingThey do DNA sequencing on all of their culturesHow to cultivate your microbiome at home by making your own fermented foodsWhat to know about fermented products and sugar and why sugar in ferments is differentHow to mitigate excess sugar in kombucha and how sugar in kombucha isn't a bad thingThe flavors of health are sour and bitterWhat are we actually feeding? We think it is our bodies but it is also our microbiome so how do we give it what it actually needsHow fermented foods help remove toxins from the bodyBacteria affects ancient wisdom and ancestral lineage in the modern worldWhat a scoby is and how it is a metaphor for global communityHow to get started with fermentation and it is easier than you think!Resources We MentionKombucha KampThe Big Book of Kombucha: Brewing, Flavoring, and Enjoying the Health Benefits of Fermented Tea by Hannah Crum

Matters Microbial #106: Cells Without Walls – Full-Frontal Bacteria September 6, 2025 Today, Dr. Dennis Claessen of Leiden University's Institute of Biology joins the #QualityQuorum to discuss how some bacteria lose their cell walls, the costs and advantages of that strategy, and how such cells can shed light on antibiotic resistance and even pathogenesis!  Host: Mark O. Martin Guest: Dennis Claessen Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Website for the Institute for Biology at Leiden University in the Netherlands. The website of Micropia, the world's best known (and perhaps only) museum devoted to microbial life, in Amsterdam, the Netherlands. The “Tardigrade Chair” at Micropia. The art of Dr. Lizah van der Aart. A video about the cell wall of bacteria. A useful overview of the cell wall of bacteria. A useful review article about the cell membrane of bacteria. An overview of peptidoglycan. The discovery of L-forms of bacteria, and Emmy Klieneberger-Nobel, who named them in 1935. A review article on L-forms (cell wall deficient) bacteria. An article relating L-forms of bacteria and the ability to resist certain antibiotics.  Here is another article. An article suggesting that L-forms could shed light on the origins of life. An article suggesting that L-forms are a strategy for dealing with stress. An article from Dr. Claessen's research group showing that L-forms of bacteria are often resistant to bacteriophage infection—and in a reversible fashion. A video presentation by Dr. Claessen. The faculty website of Dr. Claessen. The research website for Dr. Claessen's group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

SpaceX's Game-Changing ISS Test: SpaceX has successfully completed a crucial reboost test of the International Space Station (ISS) using its Dragon cargo spacecraft. This test, which raised the ISS's altitude by 5 miles, is vital for maintaining the station's orbit, especially with concerns over Russia's potential withdrawal from the ISS programme by 2028. The precision of this manoeuvre highlights SpaceX's growing capabilities in supporting the ISS's future.James Webb's Distant Galaxy Discovery: NASA's James Webb Space Telescope has identified what could be the most distant galaxy observed, Jades GS Z13.0, formed just 325 million years after the Big Bang. This finding challenges existing models of early cosmic evolution, suggesting that galaxy formation occurred much faster than previously thought.Solar Eclipse Predictions Under Scrutiny: Recent research reveals that the paths of solar eclipses may not be as precise as once believed, with potential discrepancies of hundreds of metres due to the sun's angular size. New eclipse maps are being created to account for these uncertainties, particularly for the upcoming eclipse on August 12, 2026.Perseverance Rover's Groundbreaking Find: NASA's Perseverance rover has detected convincing evidence of ancient microbial life in a rock sample from Jezero Crater. This discovery, if confirmed, could fundamentally change our understanding of life beyond Earth.Juno Mission Uncovers Callisto's Auroras: NASA's Juno mission has detected auroral footprints from Callisto, Jupiter's fourth Galilean moon, confirming that all four moons interact with Jupiter's magnetosphere. This finding suggests Callisto may have a more complex interior than previously thought.SpaceX's Ambitious Starship Infrastructure: SpaceX is rapidly developing its Starship launch infrastructure at Kennedy Space Centre, with plans for dual launch towers capable of supporting up to 76 annual launches. This expansion could significantly transform Florida's Space Coast and the global launch industry.For more cosmic updates, visit our website at astronomydaily.io. Join our community on social media by searching for #AstroDailyPod on Facebook, X, YouTube Music, TikTok, and our new Instagram account! Don't forget to subscribe to the podcast on Apple Podcasts, Spotify, YouTube, iHeartRadio, or wherever you get your podcasts.Thank you for tuning in. This is Avery and Anna signing off. Until next time, keep looking up and exploring the wonders of our universe.✍️ Episode ReferencesSpaceX ISS Test Details[NASA](https://www.nasa.gov/)James Webb Telescope Discoveries[NASA](https://www.nasa.gov/)Solar Eclipse Research[Astrophysical Journal](https://iopscience.iop.org/journal/0004-637X)Mars Perseverance Findings[NASA](https://www.nasa.gov/)Juno Mission Updates[NASA](https://www.nasa.gov/)SpaceX Starship Infrastructure[SpaceX](https://www.spacex.com/)Astronomy Daily[Astronomy Daily](http://www.astronomydaily.io/)Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-space-news-updates--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click Here

Matters Microbial #105:  Snails Farming Bacteria in the Deep Sea August 29, 2025 Let's take a deep dive into chemoautotrophy!  Today, Dr. Roxanne Beinart, Associate Professor of Oceanography at the University of Rhode Island, joins the #QualityQuorum to discuss how some marine creatures use bacterial symbioses to provide organic compounds for growth and reproduction.  Host: Mark O. Martin Guest: Roxanne Beinart Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An appreciation of the late Dr. Moselio (Elio) Schaechter from his friends at the blog “Small Things Considered.” A video from This Week in Microbiology appreciating Elio Schaechter. A video describing deep sea symbioses. A video by the great Dr. Colleen Cavanaugh about chemoautotrophy/chemosynthesis. An overview of chemoautotrophic strategies in the ocean. An overview of hydrothermal vents. A video review of  thiotrophic (sulfur based) symbiotic associations. A video about hydrothermal vent exploration. A review of hydrothermal vent communities. Alvinella, the extremophilic bristleworm discussed in this episode (includes videos). An article by Dr. Beinart and colleagues, describing how a hydrothermal vent community is disrupted by a volcanic eruption. A report on the 2020 submarine volcano eruption discussed in this episode. An interesting article about studying deep sea symbioses, coauthored by Dr. Beinart.  A great video by Dr. Beinart about her research.  Dr. Beinart's research team website. Dr. Beinart's faculty webpage. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this encore episode, we detail the oral-gut microbiota axis, detailing the oral microbiome and its relationship with the intestinal microbiome. We discuss the development of oral biofilm, the transition from plaque to dental calculus, and potential impacts of oral dysbiosis, while highlighting intestinal health and focusing on Fusobacterium nucleatum. Topics:1. Overview of the Oral Microbiome and the Oral-Gut Axis - The oral cavity and the gut: microbially dense sites. - Anatomically distinct but connected and capable of influencing each other. - The oral microbiome. - Microbial distribution: topography and chemistry of oral surfaces. 2. Oral Cavity Anatomy and Microenvironments - The vestibule and oral cavity proper. - Lined by oral mucosa, which varies in structure. - Unique ecological niches that support different microbial populations. 3. Tooth Structure and Relevance to Microbial Colonization - Teeth are embedded in the alveolar processes of the maxilla and mandible. - Tooth structure. - Long-term microbial colonization and biofilm development. 4. Biofilm / Dental Plaque Development - Biofilm begins with the formation of the acquired pellicle.- Pioneer species secreting extracellular polymeric substances (EPS).- Secondary colonizers coaggregate.- Coaggregation is species-specific.- Example.- Aerobes can lower local oxygen levels, creating micro anaerobic niches that support obligate anaerobes. 5. Maturation of the Biofilm  - Biofilm composition shifting to anaerobic, proteolytic species such as P. gingivalis. - F. nucleatum: a bridge species. 6. Mineralization and Formation of Dental Calculus - Mineralization, calcium and phosphate deposition. - Dental calculus. 7. Oral Dysbiosis  - An imbalance in the oral microbial community. - Potential signs and symptoms. - Halitosis, swollen or bleeding gums, tooth sensitivity. 8. Oral-Gut Axis and Systemic Implications - Physical, chemical, biochemical, and immunological barriers aid in preventing oral bacteria from colonizing the gut. - Oral bacteria can potentially impact intestinal health. -  F. nucleatum and IBD. 9. Oral Microbiome Testing10. Multi-Factorial Thank you to our episode sponsors: 1. ⁠⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.3. ⁠Codex Labs⁠: Explore Codex Labs' collections for ⁠acne⁠, ⁠eczema⁠, and more. Shop the ⁠BIA Collection HereGet Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Michael Lynch, Ph.D., Director of the Center for Mechanisms of Evolution at Arizona State University and Vaughn Cooper, Ph.D., professor of Microbiology and Molecular Genetics at the University of Pittsburgh, School of Medicine, examine the origins and trajectory of early microbial life (EML) and discuss the collaborative report between the American Academy of Microbiology and the Gordon and Betty Moore Foundation, which explores the journey of life on Earth, from non-living chemical compounds to early unicellular life, to the vast diversity of organisms we see today. This episode is brought to you by the American Academy of Microbiology, a think tank at American Society for Microbiology and the Gordon and Betty Moore Foundation, which has been dedicated to advancing scientific discovery for the past 25 years. Links for This Episode: Project Report Early Microbial Life: Our Past, Present and Future. Article: The Great Oxidation Event: How Cyanobacteria Changed Life. MTM Podcast: From Hydrothermal Vents to Cold Seeps: How Bacteria Sustain Ocean Life With Nicole Dubilier. Take the MTM listener survey! 

Matters Microbial #104: Antibiotic “Tolerance” and Biofilms August 21, 2025 Today, Dr. Boo Shan Tseng, Associate Professor at the University of Nevada Las Vegas School of Life Sciences, joins the #QualityQuorum to discuss bacterial biofilms and antibiotic tolerance.  Host: Mark O. Martin Guest: Boo Shan Tseng Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video overview of biofilms. A comprehensive review article on biofilms. An article describing the impact biofilms have on disease. An article describing the impact of biofilms on implanted medical devices. A link to the Center for Biofilm Engineering at Montana State University that has MANY links of interest. An overview of biofilm development. An overview of confocal laser microscopy. Studying biofilms in flow cells. An article about the role proteins play in biofilm formation, which intersects with the Tseng group's research. The technique of single cell RNA seq. The technique of mRNA-FISH. An article about porins in bacteria, and how that can relate to antibiotic resistance. An article by Dr. Tseng and coworkers on the eDNA and biofilms discussed today. A lovely video of Dr. Tseng talking about the research she and her colleagues carry out in the laboratory. Dr. Tseng's biography from the American Society for Microbiology. Dr. Tseng's laboratory group website with wonderful links and images. Dr. Tseng's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

My guest today is Dr. Kenda Rigdon. Dr. Rigdon is a microbiologist with a PhD in microbiology and virology from the University of Alabama at Birmingham. Drawing from her expertise, she explores how the gut's microbial ecosystem—comprising bacteria, yeast like Candida and Malassezia, and other microbes—interacts with genetic and epigenetic factors to influence Autism. Dr. Rigdon highlights the critical role of the birthing process, particularly how vaginal delivery seeds a newborn's gut with beneficial microbes like lactobacillus, setting the stage for healthy development in the first three years. She also delves into how yeast overgrowth, nutrient competition (e.g., for tryptophan), and environmental factors like manganese and glyphosate exposure can disrupt this delicate ecosystem, potentially exacerbating autism-related symptoms.Dr. Rigdon shares insights into the surprising links between melanin, Neanderthal DNA, and Autism. She discusses how specific genetic mutations, such as MTHFR and PAI1, can intersect with Autism. Additionally, she connects melanin production—potentially influenced by gut yeast like Malassezia—to neurological health, drawing parallels with conditions like Parkinson's. By viewing the gut as a dynamic ecosystem shaped by birth, diet, and early development, this episode offers a fresh perspective on Autism's microbial roots and practical implications for health, urging listeners to reconsider modern birthing practices and dietary choices in fostering a balanced gut microbiome.Dr. Rigdon X https://x.com/KendaRigdonDaylight Computer Companyuse "autism" for $25 off athttps://buy.daylightcomputer.com/RYAN03139Chroma Iight Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism0:00 Dr. Kenda Rigdon1:14 Journey into Microbiology4:08 The Gut's Ecosystem8:21 Genetics, Autism, & The Microbial Connection13:08 MTHFR & PAI1: Homocysteine, Methionine, Folate20:21 The Role of Yeast in Health & Disease; Serotonin, Candida26:39 The Fight for Tryptophan31:14 Impact of Birthing Method on Gut Health (!)33:13 Modern versus Evolutionary Births, Breastfeeding; Oxygen, Acidity, PH37:15 Melanin, Cell Protection, Neanderthal DNA, Autism40:46 Neuromelanin; Biological Energy, Melanocytes43:20 Neanderthal's & Modern Disease & Environments47:23 Microbes in the Brain53:21 Manganese & Gut Health58:22 Gut-Brain Connection & Microbial Balance01:03:19 Early Gut Health & Development; Modern Insults01:07:21 Future Direction in Gut Health & Kenda's Passion & LoveX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Matters Microbial #103: Giant Bacteria and Bigger Questions August 14, 2025 Today, Dr. Jean-Marie Volland, Assistant Professor at the University of California in Santa Barbara joins the #QualityQuorum to discuss the discovery and analysis of the (so far) largest bacterium known:  Thiomargarita magnifica, which can be a centimeter long! Definitely #OMG and #WTM! Host: Mark O. Martin Guest: Jean-Marie Vollard Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a review article discussing the environmental persistence of antibiotic resistance genes. Here is a link to Episode 41 of this podcast, with Dr. Esther Angert, on the wily ways of Epulopiscium. A review article regarding “giant bacteria.” A video explaining the surface area versus volume issue discussed on this podcast. An interesting article exploring how much “territory” is within a bacterial cell; this is relevant to bacterial polyploidy. A review of Epulopiscium, the first of the giant bacteria described. Here is a video of Epulopisicum.   An article describing polyploidy in Epulopiscium.  A review of Thiomargarita nambiensis, another giant bacterium with an interesting strategy. Here is a video of T. nambiensis.  An essay from “Small Things Considered” about the very, very strange world of Achromatium, which is so worth your time. The first report of Thiomargarita magnifica, the world's largest bacterium (thus far) by Dr. Volland and coauthors. Here is a report on this discovery for novice micronauts. A great review about giant microbes by Dr. Volland. A more recent article on T. magnifica by Dr. Volland and colleagues. A video regarding T. magnifica. A video by Dr. Volland describing T. magnifica work. A lovely essay regarding how Dr. Volland and family trekked California searching for giant microbes. Don't miss! The research lab website for Dr. Volland and colleagues, with so much interesting information. The faculty website for Dr. Volland at UC Santa Barbara. Intro music is by Reber Clark

Kilayim [Part 2]: Keeping a kilayim tree; Bracha on blossoming tree; Shehechiyanu on Rosh Hashanah; Microbial fermentation. See seforim by Rabbi Cohen at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.kashrushalacha.com⁠

Matters Microbial #102: Teaching Through the Issues with Microbes! July 31, 2025 Today, Dr. Davida Smyth, Professor of Biology and Deputy Director of the National Center for Science and Civic Engagement at Texas A&M University-San Antonio joins the #QualityQuorum to discuss her impressive work using microbiology to engage students at the intersection of cutting edge research and current events. #MicrobialLiteracy! Host: Mark O. Martin Guest: Davida Smyth Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The American Society for Microbiology Carski Award website. The American Society for Microbiology Distinguished Lecturer website. The concept of “classroom agreements.” The 10:1 (microbial cells to human cells) story, and a related article. The 3-2-1 approach to learning in the classroom. Dr. Smyth's “How Toilets Changed the World” class. The American Society for Microbiology Curriculum Guidelines. The National Science Foundation's “Vision and Change” website describing improvements in biology education. The American Society for Microbiology profile for Dr. Smyth. A video seminar by Dr. Smyth describing open science in undergraduate education. The website for the National Center for Science and Civic Engagement. Dr. Smyth's faculty website. Dr. Smyth's superb research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

If you've struggled with gut imbalances, recurrent or chronic infections, or you're just curious about upgrading your oral or gut microbiome, this episode of Vitality Radio is a must-listen. Jared welcomes Dr. Shawn Manske, ND, from the Biocidin Clinical Education team to dive deep into one of the most respected formulas in the natural health world—Biocidin. With over 35 years of clinical use and growing popularity, Biocidin is finally available to the public, and it's making a big impact. Dr. Manske breaks down how this unique botanical blend supports microbial balance in the gut, helps maintain oral health, and addresses issues like SIBO, candida, and biofilms. You'll hear why Biocidin stands apart from other antimicrobials—supporting the good guys while targeting the bad. Jared and Dr. Manske also discuss the importance of pairing Biocidin with binders and spore-based probiotics, how to introduce it safely (especially for sensitive individuals), and why it may be a game-changer for immune health, brain fog, and long-standing digestive complaints. They also explore the powerful benefits of Biocidin's oral care products and how the oral microbiome may play a more crucial role in systemic health than most people realize. Products:CellCore Biocidin ProductsCellCore BioToxin BinderVital 5 Precision Probiotic Vital SporesAdditional Information:#543: How to Choose the Right Binder for Detox, Parasites, Mold, and MetalsVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Matters Microbial #101: Electrifying News about Cable Bacteria July 25, 2025 Today, Dr. Nicole Geerlings from the University of Vienna in Austria joins the #QualityQuorum to discuss some of the wonderful work she and colleagues have carried out studying the wild, weird, and wonderful world of cable bacteria, which can conduct electricity over microbially enormous distances!  Definitely time for #OMG and #WTM! Host: Mark O. Martin Guest: Nicole Geerlings Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode This just became available:  a wonderful short introduction to day's topic, the cable bacteria, from Asimov Press.  It is an absolute must read for everyone interested. Here is a link to the Summer Science Program, a wonderful outreach program for high school juniors. An essay about Nobel Prize winning Albert Szent-Györgyi, who stated that life was a matter of electrons finding a place to rest.  Here is a short video introduction to his work. A video introduction to microbial metabolism. A video introduction to electron transport.  Remember that bacteria and archaea are VERY skilled at using different electron donors and acceptors than eukaryotic life. The really fun concept of the “Jagendorf Jump,” showing electron transport vs. pH in chloroplasts. An overview of the microbial fuel cell concept.  Here is a nice overview I highly recommend. A commercial source for you to build your own microbial fuel cell. A DIY approach to building a MFC.  An ESSENTIAL overview to the idea of electrons in microbial sediments. A review article about cable bacteria.  Here is another fine review. This is a third great introduction to cable bacteria. And here is a video overview.   An article by Dr. Geerlings and colleagues describing cable bacteria for new #Micronauts.  HIGHLY RECOMMENDED. An review of stable isotope probing in microbiology. Here is a video seminar using SIP in microbiology. An overview of Nano-SIMS and how it is used in microbiology.  Here is another review.   A deeply wonderful article by Dr. Geerlings and colleagues suggesting that inactive cells with the “microbial cable” are still conducting electrons! Dr. Geerlings postdoctoral scholar website. Links and References on Cable Bacteria from Dr. Geerlings: 1. Here is a website from the group of Prof. Dr. Filip Meysman from the University of Antwerp, which includes a great video on the electron conductivity of cable bacteria. 2. The first paper describing redox half-reactions separated by long-distance electron transport. Nielsen, L. P., Risgaard-Petersen, N., Fossing, H., Christensen, P. B., and Sayama, M. (2010). Electric currents couple spatially separated biogeochemical processes in marine sediment. Nature 463, 1071–1074. doi: 10.1038/nature08790 3. The paper describing the discovery of cable bacteria. Look into the supplemental material for the excellent experimental set-up to prove that the cable bacteria are the ones doing the long-distance electron transport. Pfeffer, C., Larsen, S., Song, J., Dong, M., Besenbacher, F., Meyer, R. L., et al. (2012). Filamentous bacteria transport electrons over centimetre distances. Nature 491, 218–221. Doi: 10.1038/nature11586 4. A paper that dives into the conductivity of the cable bacteria network and shows that these fibres can conduct electrons just as well as a copper wire. Meysman, F. J. R., Cornelissen, R., Trashin, S., Bonné, R., Martinez, S. H., van der Veen, J., et al. 2019. A highly conductive fibre network enables centimetre-scale electron transport in multicellular cable bacteria. Nat. Commun. 10:1–8. doi: 10.1038/s41467-019-12115-7 5. This paper describes how cable bacteria activity generates a layer of iron oxyhydroxides on the top of the sediment layer and how this delays the release of sulfide into the water column for several weeks in a seasonally hypoxic basin in the Netherlands. Seitaj, D., R. Schauer, F. Sulu-Gambari, et al. 2015. “Cable Bacteria Generate a Firewall Against Euxinia in Seasonally Hypoxic Basins.” Proceedings of the National Academy of Sciences of the United States of America 112: 13278–13283. 6. This paper describes how the catabolic division of labor is coupled to an anabolic division of labor where cells reducing oxygen cannot grow and therefore provide a “community service” for the rest of the filament. Nicole M. J. Geerlings, Cheryl Karman, Stanislav Trashin, Karel S. As, Michiel V. M. Kienhuis, Silvia Hidalgo-Martinez, Diana Vasquez-Cardenas, Henricus T.S. Boschker, Karolien de Wael, Jack J. Middelburg, Lubos Polerecky, and Filip J.R. Meysman. Division of labor and growth during electrical cooperation in multicellular cable bacteria. Proc. Natl. Acad. Sci. U.S.A. 117, 5478–5485. Doi: 10.1073/pnas.1916244117   Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

This week on the podcast, Patrick and Tracy welcome Joan Slonczewski, author of Minds in Transit. About Minds in Transit: In the hundred-level city of Iridis, human lords recycle diamonds and emeralds down to the Underworld while sentient machines pilot lightcraft and perform surgeries. Microbial minds expand the brains of scientists and artists. The artist […] The post Episode 671-With Joan Slonczewski appeared first on The Functional Nerds.

TWiM explores the use of gas sensors and machine learning to identify microbes and antimicrobial resistance in clinical specimens, and how a harmful algal bloom species releases thiamin antivitamins to suppress competitors.   Become a patron of TWiM.   Links for this episode: Microbial and antimicrobial resistance diagnostics (Cell Biomaterials) Thiamin antivitamins suppress algal competitors (mBio) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv  

Matters Microbial #100: What's the Buzz on Phage Therapy for Honeybees? July 14, 2025 Today, Dr. Heather Hendrickson from the University of Canterbury in New Zealand joins the #QualityQuorum to discuss the research she and her team are conducting on bacteriophage therapy to protect vulnerable honeybees from bacterial infections. Host: Mark O. Martin Guest: Heather Hendrickson Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is the website for a former undergraduate research student of mine, Dr. Paula Welander, now a professor and administrator at Stanford University.  Yes, I am proud. Here is a link to another former undergraduate research student of mine, Dr. Krista Venecia Edmiston, now a professor at California Health Sciences University.  Yes, I am proud. A review on cell shape in bacteria. A review on the cytoskeleton of bacteria and archaea. I am a great admirer of Dr. John Roth, and his clearheaded and direct approach to microbial genetics.  Here is his academic website with many publications. An article about the causative agent of American Foulbrood, Paenibacillus larvae. An overview of American Foulbrood's impact on honeybees. The honeybee lifecycle. Beemites and honeybees. A video overview of bacteriophage therapy against bacterial diseases. An explainer of bacteriophage plaques. A video overview of lytic versus lysogenic bacteriophages. Dr. Graham Hatfull and his simply amazing SEAPHAGEs program, teaching so many people about isolating and studying bacteriophages. An article from Dr. Hendrickson's laboratory exploring cell shape in bacteria. An article from Dr. Hendrickson's laboratory explaining the importance of protecting honeybees from American Foulbrood, and the approach her laboratory uses. An article from Dr. Hendrickson's laboratory describing a community based approach to search for bacteriophages of Paenibacillus larvae. An article from Dr. Hendrickson's laboratory analyzing the types of Paenibacillus attacking bacteriophages isolated in New Zealand. An article from Dr. Hendrickson's laboratory describing an improved method for isolating bacteriophages. A truly great video from Dr. Hendrickson some years ago, explaining her research.  This is a “must see.” Dr. Hendrickson's faculty webpage. Dr. Hendrickson's informative research group website. This section of Dr. Hendrickson's research group website is devoted to outreach, and so very worth your time. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

What if we could grow nutritious, sustainable protein—not in months or weeks—but in just one day? This episode's guest is doing just that. Rather than going big with animal agriculture, MicroHarvest is going small with microbial agriculture.  A huge number of animals are used to feed both our pets and the animals we raise for food. Kate Bekers, the CEO and co-founder of MicroHarvest, is seeking to change that. She's running a fast-rising European biotech startup using fermentation to produce high-quality protein from microbes—in just 24 hours. Based in Hamburg and Lisbon, MicroHarvest is on a mission to reshape how the world thinks about protein production. Rather than growing plants or animals, they grow single-cell microbes in bioreactors, yielding a high-protein, micronutrient-rich ingredient that can be used in everything from animal feed and pet food to, eventually, human food. With 10 million euros raised and hopefully a new 30 million euro round on the horizon, their process is fast, efficient, and radically resource-light—requiring far less land, water, and energy than traditional agriculture. Already able to produce one ton of their product per day, MicroHarvest is proving that microbial protein isn't just a lab experiment—it's a scalable, real-world solution. In this episode, Kate shares what it takes to bring biotech innovation to market, and why she believes protein production should be faster, cleaner, and closer to the consumer. We talk about the company's entry into pet food and aquaculture, and what the future holds for sustainable protein made from the tiniest organisms on Earth. If you're curious about the future of food, circular economies, or how to build a business that's good for animals and the planet, this conversation is for you.

In this episode, we detail Small Intestinal Fungal Overgrowth (SIFO), with a focus on fungal biofilm formation and its role in promoting microbial persistence and evasion of host immune responses. We discuss the phenotypic plasticity of Candida species, as well as biofilm matrices adherent to the intestinal mucosa. We further highlight common symptoms of SIFO as well as the effects of hypochlorhydria, reduced pancreatic enzyme and bile output, impaired motility, diminished commensal bacterial populations, and weakened mucosal immunity.Topics: 1. Introduction- Focus on the gut mucosal barrier.- Emphasis on Small Intestinal Fungal Overgrowth (SIFO) and biofilms.2. Intestinal Barrier Anatomy- The mucosa: epithelium, lamina propria, and a thin band of smooth muscle.- The epithelial layer.- Covered by protective mucus composed of mucin glycoproteins secreted by goblet cells.- In the small intestine: less dense mucus.3. Epithelial Integrity- Tight junctions.- Paracellular barrier preventing uncontrolled antigen passage.4. Lamina Propria5. Overview of Small Intestinal Fungal Overgrowth (SIFO)- SIFO involves fungal overgrowth in the small intestine, commonly Candida species.- Small intestines: Low microbial density due to motility, gastric acid, bile acids, immune surveillance, and more.- Contributing factors: hypochlorhydria, impaired motility, reduced digestive enzymes, diminished competitive flora, lowered immunity, and more.6. Candida Pathogenicity- Candida exhibits phenotypic plasticity: yeast and hyphal forms.- Biofilm formation.7. Biofilm Formation- Biofilms are structured communities of microbes within a self-produced extracellular matrix.- Resistance to antimicrobials and immune defenses.- Can develop on intestinal mucosa and in various other regions.8. SIFO and SIBO Overlap- Root causes and overlap between SIFO and Small Intestinal Bacterial Overgrowth (SIBO).- Common symptoms.9. Gastric Acid in More Detail- Stomach epithelium includes mucous, parietal, chief, and enteroendocrine cells- Parietal cells secrete hydrochloric acid.- HCl denatures proteins and aids in inhibiting pathogens.- Hypochlorhydria: possible causes. 10. Downstream Effects of Low Acid11. Gut Motility in More Detail- Motility involves rhythmic smooth muscle contractions.- Enteric nervous system (ENS): myenteric and submucosal plexuses.- Dysautonomia and motility.12. SIFO Contributing Factors13. Candida Regulation- Candida generally remains in unicellular yeast form under homeostatic regulation.- Controlled by microbial competition, host defenses, antifungal peptides, and more.14. Role of Mucus and sIgA- Mucosal immunity (including sIgA) aids in regulating Candida populations.- Low sIgA levels (due to stress, immune suppression, dysbiosis,…) weaken defense 15. Conclusion- Mucosal barrier structure.- SIFO and Candida.- Biofilm formation, microbial persistence, and mucosal disruption.- SIFO and SIBO.- Multifactorial nature of fungal dysbiosis, types of biofilms, and small intestinal overgrowth.Thank you to our episode sponsor: 1. OmneDiem®'s Histamine Digest® and Histamine Digest® PureMAX 2. Histamine Digest® Histamine Complete with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Matters Microbial #99: Albert Kluyver—Microbial Unity and Diversity in Metabolism July 10, 2025 Today, Dr. Dianne Newman of Caltech joins the #QualityQuorum live at ASM Microbe in Los Angeles, to discuss the role that Albert Kluvyer played in helping microbial scientists to understand the unity and diversity to be found in microbial metabolism. Host: Mark O. Martin Guest: Dianne Newman Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A review article by Roberto Kolter about the history of microbiology. An overview of the “Delft School” of microbiology.  Here is another article on that topic. The 1924 article by Albert Kluyver that Dr. Newman references—very much worth you time. A video overview of microbial metabolism.  Here is a recent article on that topic. A short biography of Albert Kluyver. Here is another article on that topic. A wonderful 2023 video seminar by Dr. Newman exploring the unity and diversity of microbial metabolism.  Much recommended. Dr. Newman's faculty website. Dr. Newman's very impressive research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this episode of The Poultry Nutrition Blackbelt Podcast, Dr. Cangliang Shen from West Virginia University explores how microbial contamination in poultry poses emerging challenges for food safety. He discusses the use of surrogate bacteria, thermal processing techniques, and sanitation protocols in real-world poultry feed operations. Listen now on all major platforms!"We find that temperature up to 80°C can reach a three log reduction for the efficiency, which gives us hints for developing sanitation procedures and hazard plans for local industry facilities."Meet the guest: Dr. Cangliang Shen earned his Ph.D. in Meat Science and Food Safety from Colorado State University, with earlier training in Veterinary Medicine. He is currently a Professor and Extension Specialist at West Virginia University, focusing on improving poultry meat and feed safety through microbiological research and hazard planning.Click here to read the full research article!Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:04) Introduction(03:27) Current research focus(04:38) Temperature thresholds effectiveness(06:50) Ingredient impact on safety(09:44) Hazard planning insights(13:11) Future research directions(14:55) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like:* Kemin* Kerry- Poultry Science Association- Anitox- BASF

Are you struggling to find sustainable solutions for your crops in an ever-changing agricultural landscape?I sat down with Jessica Staha, CEO of LPC Naturals, to discuss the fascinating world of microbials in agriculture. With a background in molecular biology and genetics, Jessica brings a wealth of knowledge to the table, having worked in various industries before finding her passion in agricultural technology.We delved into the unique challenges faced by both indoor and outdoor farming, and how microbials can provide innovative solutions. Jessica explained how their proprietary isolate of Beauveria bassiana works as a plant stimulant, helping crops withstand various stresses. She emphasized the importance of educating farmers and growers about the benefits of microbials, as they offer a more holistic approach to plant health compared to traditional chemical solutions.Throughout our conversation, we touched on the evolving landscape of controlled environment agriculture, the impact of extreme weather on farming, and the potential for collaboration within the industry. Jessica shared insights on leadership in a startup environment and the importance of maintaining work-life balance in the fast-paced world of agricultural innovation.If you're curious about the future of farming and how microbials could revolutionize crop management, this episode is a must-listen. Tune in to gain valuable insights from an industry expert and discover how these tiny organisms could make a big difference in agriculture.Thanks to Our SponsorsCEA Summit East - https://indoor.ag/cea-summit-east-2025/Indoor AgCon - https://indoor.ag/Key Takeaways5:57 From corporate to entrepreneurship challenges11:47 LPC Naturals origin and microbial solutions17:57 Educating farmers on microbial benefits24:59 Preparing environments for microbial use30:20 Balancing entrepreneurship and personal well-being35:17 Collaboration opportunities in microbial researchTweetable Quotes"DNA is DNA is DNA. It doesn't matter the organism. And so again, it's this universal language that you can communicate with.""In a controlled sector, you're really pushing those plants to an extreme. Really fast cycle times, beautiful, consistent responses are needed. And then on top of it, packaging, handling, long shelf lives are needed.""As more chemicals are being pulled and aren't being allowed to be used, it's clear that more people are doing a better job at communicating the efficacy of microbials in agriculture and vertical spaces."Resources MentionedWebsite - https://lpcnaturals.com/LinkedIn - https://www.linkedin.com/in/jessica-stahaInstagram - https://www.instagram.com/primesuperiorgrow/Facebook - https://www.facebook.com/primesuperiorgrowYouTube - https://www.youtube.com/@primesuperiorgrowConnect With UsVFP LinkedIn - https://www.linkedin.com/company/verticalfarmingpodcastVFP Twitter -

Matters Microbial #98: Nesting Dolls of Endosymbiosis July 3, 2025 Today, Dr. John McCutcheon of Arizona State University joins the #QualityQuorum to discuss the work he and his research group do to investigate the strategies by which microbes become symbionts of other cells. After all, the mitochondria and chloroplasts of eukaryotic cells, including yours, were once bacteria! Host: Mark O. Martin Guest: John McCutcheon Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video about the symbiosis of Hydra virdissima, which captured my heart when I was young.  Look at those symbiotic algae!  Here is an overview of this topic. A video describing the Rhizobium – legume nitrogen fixing symbiosis in all of its glory—by my PhD advisor, the great Dr. Sharon Long.  Here is an overview of this topic.   An appreciation of Paul Buchner's very important book, “Endosymbiosis of Animals with Plant Microorganisms.” A wonderful review by Dr. McCutcheon on how symbioses form. A wonderful essay by Ed Yong about an event that made eukaryotic cells possible:  how bacteria became mitochondria. A story about an anaerobic protist that lost its mitochondria completely. A bacterial symbiont of mitochondria, the “midichlorian.” The recent discovery of a new integrated symbiont that has become an organelle, the nitrosome. The “X-bacteria” and amoebae story. A retrospective on endosymbiosis, and Paramecium based on Tracey Sonneborn's work. An essay on aphids and bacteria. An article on the Moranella/Tremblaya symbiosis. An article on “bacteria inside other bacteria” found in several symbioses, written by Dr.McCutcheon and colleagues. Genomic instability in bacterial endosymbionts. An article on cicadas and bacterial endosymbionts from Dr. McCutcheon and colleagues. An article on mealybugs and bacterial endosymbionts from Dr. McCutcheon and colleagues. Dr. McCutcheon's thoughts on his career path (so worth reading). The Center for Mechanisms of Evolution research institute in which Dr. McCutcheon works. Dr. McCutcheon's faculty website. Dr. McCutcheon's (and his research team's) wonderful research website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

This e[pisode of SpaceTime is brought to you with the support of NordVPN, SpacTime's official VPN service. And have we got a great offer for you, with a 30 Day Money-Back guarantee! To check out the details vist nordvpn.com/stuartgary or use the coupon code STUARTGARY at checkout.In this episode of SpaceTime, we explore the latest discoveries and research that are reshaping our understanding of Mars and the effects of solar activity on planetary climates.Curiosity Rover's New Martian Rock SamplesNASA's Mars Curiosity rover has drilled into a new region of Martian rock, revealing intriguing features that may provide insights into whether the planet ever had conditions suitable for life. The rover's findings include unique boxwork patterns formed by groundwater, suggesting that even as Mars dried up, water was still present below the surface. As Curiosity ascends Mount Sharp, scientists are eager to understand the implications of these patterns and the mineral cements involved, which may hold clues to Mars' climatic history and the potential for ancient microbial life.Solar Flares and Weather PatternsA groundbreaking study published in the Astronomical Journal has uncovered a connection between solar flares and short-term changes in weather patterns on exoplanets. Researchers found that flares from a planet's host star can cause measurable climate shifts within days, highlighting the importance of solar activity in modulating atmospheric behavior. This research not only enhances our understanding of exoplanet habitability but also suggests that solar variability may influence weather systems on Earth, particularly in volatile regions.Nasa's In-Flight Imagery ProjectNASA's Scientifically Calibrated in Flight Imagery (SCIFLI) team is set to gather vital data during the reentry of a European aerospace company's demonstration capsule. Utilizing advanced instruments, including a spectrometer and high-definition telescope, SCIFLI aims to capture real-time performance data that will refine computational models for future space missions. This mission highlights the importance of empirical data in enhancing safety and performance for crewed and robotic space exploration.www.spacetimewithstuartgary.com✍️ Episode ReferencesAstronomical Journalhttps://iopscience.iop.org/journal/1538-3881NASA Curiosity Roverhttps://mars.nasa.gov/msl/NASA SCIFLI Teamhttps://www.nasa.gov/langley/scifliBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-space-astronomy--2458531/support.

Scientific Sense ® by Gill Eapen: Prof. David Pearce is Professor of Applied Sciences at Northumbria University. The underlying theme of his research is to use microbiology to understand Polar ecosystem function and the potential for shifts in biogeochemical activity that may result from environmental change.Please subscribe to this channel:https://www.youtube.com/c/ScientificSense?sub_confirmation=1

What is the microbiome? Where is it? Why is it so foundational to many areas of health? And how can we support it besides avoiding antibiotics and taking probiotics? In today's episode I answer these questions, plus talk about specific testing, the nuances of what makes up the microbiome besides bacteria, and the many ways we can help keep it healthy or repair damage. Plus! Top tips for picking probiotic supplements, herbs to work with, and foods (in addition to fermented vegetables) that support your microbiome.Mentioned in today's episode is Missing Microbes by Martin Blaster.The Family Herbalism program and the Community Herbalistprogram through Herba Remedium are now open for registration. Sign up early and get 10% off. Early bird pricing ends July 15th!The Herbal Collective is open tomorrow!!! Go to the website and check out your two options – will you join the lite Collective, or the full membership for just $9 a month? Either way you get access to all of my podcastepisodes organized by topic and all the downloadables I've offered to the public. In the full membership you will also get an exclusive herb walk series, weekly meetups, free access to classes I offer on my website, and starting next year, free monthly, live classes. Go check it out and jump into the Herbal Collective today!Monthly newsletters from yours truly are available with podcast updates, favorite resources, and other educational material. Visit www.laureltreewellnessllc.com and scroll down to the bottom of the front page to sign up!Also available on my website is all the information you need to schedule an appointment with me, and we can help you create a holistic wellness plan to work on your health goals.Thank you for listening!

In this encore episode, we detail the enteric nervous system and regulation of gastrointestinal motility. We discuss factors including dysautonomia, stress, microbial overgrowth, and more, with regards to potential effects upon gastrointestinal motility. We further detail symptoms of altered GI motility. Topics:1. Introduction to Gastrointestinal Motility- Orchestrated contraction of smooth muscles that propel contents along the digestive tract.  - Roles in mixing, absorption, and preventing bacterial overgrowth.- Disruptions in motility. 2. The Enteric Nervous System (ENS) and Its Role- Myenteric and submucosal plexus.- Coordinating contractions and relaxations for effective motility. - Mucosa includes epithelium, lamina propria, and muscle.  - Submucosa houses the submucosal plexus.  - Muscularis externa. - Inner circular and outer longitudinal muscle layers with the myenteric plexus in between.   3. The Role of Interstitial Cells of Cajal (ICCs)- Specialized pacemaker cells in muscular layers  - Generate slow-wave electrical activity to synchronize smooth muscle contractions  - Critical for peristalsis.- Work with neural inputs to fine-tune gut motility   4. Dysautonomia and Its Impact on Gut Motility- Dysfunction of the autonomic nervous system (ANS)  - Motility impacts- Microbial overgrowth, SIBO 5. Gastrointestinal Dysmotility- Neurological dysregulation - Structural abnormalities and smooth muscle dysfunction  - Hormonal imbalances - Microbial overgrowth - Autoimmunity  6. The HPA Axis- Hypothalamus, pituitary gland, adrenal glands  - Central to the stress response and interlinked with gut function  - The amygdala and PVN of the hypothalamus  - CRH stimulates ACTH, leading to cortisol release from adrenal glands   7. Cortisol and Gut Barrier Function- Cortisol is a glucocorticoid that modulates immune function and gut physiology  - Chronic cortisol exposure can impair tight junction (TJ) integrity  - Increases paracellular permeability and allows passage of antigens and endotoxins   8.Stress-Induced Changes in Gut Motility- Slow gastric motility - Increased colonic motility  9. Symptoms of GI Dysmotility10. Addressing Root Cause(s)Thank you to our episode sponsor:1. Shop ⁠⁠⁠⁠⁠⁠⁠⁠Fresh Press Farms⁠⁠⁠'⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Peach Cider Vinegar⁠⁠⁠⁠⁠ at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

This episode was recorded at the 2025 Florida Ruminant Nutrition Symposium. Microbial protein has always been Dr. Frikins' main interest. It's the most important and consistent source of protein for the cow, with a very high amino acid content. Histidine is the only exception, but bypass protein sources high in histidine complement microbial protein well. Our assessment of microbial protein is all based on prediction models. In his presentation, Dr. Firkins talked about what we can do to have consistently high microbial protein production and how to make the best use of the models. He touched on starch and fat content as two areas of focus, emphasizing a balanced diet to achieve a balanced supply of microbial protein. (5:36)Dr. Firkins notes that about 90% of the bacteria in the rumen can't be cultured, and there is great diversity in the rumen. There's a core group of bacteria that almost every cow has that are really good at their job because they've been co-selected along with the cow for fiber digestion. The panel discusses how much the microbiome changes over time, host interactions with the microbial population, and inoculation of calves at birth and weaning. (8:47)Dr. De Souza and Dr. Faciola talk about starch associative effects and their impacts on fiber digestibility, how sugars impact the rumen and butyrate production, and the importance of butyrate in de novo milk fat synthesis. Dr. Frikins hypothesizes that when sugars improve fiber digestibility, the sugar stimulates how fiber digesters do their job. Some studies have shown an increase in rumen pH when sugars are supplemented, which may be part of the mechanism of improved fiber digestibility. However, he doesn't recommend using sugars when there is a lot of starch in the diet. (13:38)Dr. Faciola and Dr. Firkins discuss some of the finer points of the dietary starch and fiber digestibility relationship. What are you replacing when you add more starch? What is the proper amount of effective fiber in higher-starch diets? On the other hand, if you decrease starch a little bit, there might be more room for fat. Well-managed cows with adequate effective fiber can probably handle more starch. Dr. Firkins underlines that starch is more digestible than fiber and thus supports microbial protein, but an optimum level is desirable, perhaps 28-20%. (20:37)The panel talks about microbial growth efficiency and the energy-spilling mechanisms some bacteria have. Some models suggest that starch-digesting bacteria have higher maintenance energy requirements. The group then pivots to methane production and available feed additives marketed to reduce methane. Dr. Firkins notes that there is quite a bit of variability in the additives. He emphasizes that if we're using these products, we need to know and measure what's in them and have them be consistent. This is challenging due not only to variability in product, but also rumen adaptation. Dr. Firkins also reminds the audience that improving the cow's efficiency in general in a variety of ways will lead to a smaller environmental footprint. This can range from improving reproductive efficiency to understanding differences in the microbiome of cows who emit more or less methane and trying to shift microbial populations to those with lower emissions. (23:12)Dr. De Souza and Dr. Firkins discuss fatty acid supplementation and fiber digestion relationships. Dr. Firkins explains that in the microbiology literature, it's common to culture bacteria in a simple or complex medium, then add yeast culture. Interestingly, the yeast culture contains a lot of palmitic acid, which has been shown to improve fiber digestibility. He suggests the cell membrane of the bacteria is very critical. When fat supplementation depresses fiber digestibility, he suspects it's disrupting the bacterial membrane. Dr. De Souza recommends 1-2% palmitic acid in the diet for optimal results. (33:58)The panel touches on the importance and relevance of in vitro fermentation work, why histidine is the limiting amino acid in microbial protein, and Dr. Firkins' passion for protozoa. (43:08)Panelists share their take-home thoughts. (53:40)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

On this ID the Future from the archive, host Jonathan Witt speaks to molecular biologist and professor Dustin Van Hofwegen about his research into the engineered complexity in microbial life. Hofwegen shares his research on the famous decades-long E. coli evolution experiment conducted by Richard Lenski, which showed the sudden appearance of an ability to utilize citrate after many generations. However, Van Hofwegen's own experiments demonstrated that this "evolutionary innovation" actually points to the intelligent design built into living systems instead of an undirected process like natural selection. Source

True health encompasses so much more than just diet and exercise. However, you don't need complicated routines, a lot of money, or elaborate gadgets to make a positive impact on your health. Some of the most powerful things you can do to improve your longevity, boost your immune system, and lower your stress have to do with simple behaviors and habits you can create in your home. Today, you're going to learn about the impactful role that community can have on your microbiome, your disease risk, and your overall health. On this episode of The Model Health Show, you're going to hear my conversation with the incredible Dr. Amy Shah for her podcast, Save Yourself. In this conversation, we discussed the importance of shared family meals, how to prioritize eating real food, and why your relationships are a key determinant of your health. This episode is packed with the science behind how cultivating healthy relationships can influence your microbiome, your sleep, your immune system, and so much more. You're also going to learn the top two most important things you can do to transform your health. I hope you enjoy my conversation with Dr. Amy Shah!  In this episode you'll discover:  The most important part about being human. (09:48) How eating with your family can impact your health. (12:22) Why being part of a community can improve your microbiome. (14:47) The health benefits of multi-generational living. (17:52) An interesting fact about humans, evolution, and menopause. (23:13) Why creating your own community can transform your life. (25:24) How sharing meals with your children can reduce their risk of obesity and disordered eating. (28:04) The connection between the time spent at a table and health outcomes. (33:45) What the #1 factor is that influences longevity is. (38:04) Which hormone is the antidote to stress. (39:27) Why personalization is the key to health. (41:22) The most powerful nutrition shift you can make. (41:44) How American children's diets have become inundated with ultra-processed food. (42:37) The #1 way to minimize the ultra-processed food in your diet. (45:50) What post-ingestive feedback is. (49:14) What sleep nutrients are. (54:41) How often you should aim to share a meal with others. (58:09)  Items mentioned in this episode include:  Beekeepersnaturals.com/model - Save 25% sitewide through May 27!  PaleoValley.com/model - Use code MODEL for 15% off! Save Yourself with Dr. Amy Shah - Subscribe to Dr. Amy Shah's podcast! Eat Smarter Family Cookbook - Transform the health, fitness, and connection of your entire family with the Eat Smarter Family Cookbook!  Be sure you are subscribed to this podcast to automatically receive your episodes:   Apple Podcasts Spotify Soundcloud Pandora YouTube   This episode of The Model Health Show is brought to you by Beekeeper's Naturals and Paleovalley. Reinvent your medicine cabinet for with clean, effective products powered by the beehive & backed by science. Shop the Memorial Day Sale now through May 27th and get 25% off sitewide at beekeepersnaturals.com/model. Use my code MODEL at PaleoValley.com/model to save 15% sitewide on nutrient dense snacks, superfood supplements, and more.