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In this episode of the Inside JABA Series podcast, we dive into a fascinating discussion on health-related routines for adults with intellectual and developmental disabilities (IDD). Dr. Katie McHugh, Dr. Claudia Dozier, and Editor-in-Chief Dr. John Borrero share insights from their recent study, Synchronous Reinforcement Schedules Promote Tolerance of Health-Related Routines for Adults with Disabilities. The conversation explores how synchronous reinforcement schedules—where reinforcement occurs in real time alongside behavior—can improve tolerance for essential routines like toothbrushing, bathing, wearing medical devices, and more. The research team highlights case studies, methodological considerations, and the broader implications for clinical practice. Key Topics Covered ✅ Synchronous reinforcement schedules and why they may be more effective (and preferred) than delayed reinforcement. ✅ Applications for health routines such as toothbrushing, bathing, mask-wearing, GPS bracelets, helmets, and pulse oximeters. ✅ Collaborative service delivery with nursing and medical professionals. ✅ Challenges in participant consent and maintaining experimental control. ✅ Importance of measuring both behavioral outcomes and affective states. ✅ Future research directions, including reinforcer assessments, continuous vs. discontinuous schedules, and maintaining treatment effects. Next Steps and Future Directions Editorial updates for broader keyword usage to increase accessibility outside of behavior analysis. Comparing graduated exposure with contingent vs. synchronous reinforcement interventions. Implementing more systematic preference and reinforcer assessments in future studies. Exploring hybrid approaches (e.g., combining graduated exposure with synchronous reinforcement). Collecting more comprehensive data on participant affect and treatment integrity. Resources & References Dr. Dozier's lab website. Dr. Dozier's KU faculty page. KU ABS online and on-campus graduate programs. DeLeon, I. G., Hagopian, L. P., Rodriguez-Catter, V., Bowman, L. G., Long, E. S., & Boelter, E. W. (2008). Increasing wearing of prescription glasses in individuals with mental retardation. Journal of Applied Behavior Analysis, 41(1), 137–142. Diaz de Villegas, S. C., Dozier, C. L., Jess, R. L., & Foley, E. A. (2020). An evaluation of synchronous reinforcement for increasing on-task behavior in preschool children. Journal of Applied Behavior Analysis, 53(3), 1660–1673. Hardesty, E. M., Lerman, D. C., & Hardee, J. L. (2023). A comparison of synchronous and noncontingent stimulus delivery on task engagement. Journal of Applied Behavior Analysis, 56(3), 664–673. Leslie, S. C., Dozier, C. L., Kamlowsky, M. E., McHugh, C. L., Diaz de Villegas, S. C., & Kanaman, K. C. (2024). Using synchronous reinforcement to increase mask wearing in young children. Behavioral Interventions, 39(1), 1–29. McHugh, C. L., Dozier, C. L., Diaz de Villegas, S. C., & Kanaman, N. A. (2022). Using synchronous reinforcement to increase mask wearing in adults with developmental disabilities. Journal of Applied Behavior Analysis, 55(4), 1157–1171. Williams, D. C., & Johnston, J. M. (1992). Continuous versus discrete dimensions of reinforcement schedules: An integrative analysis. Journal of the Experimental Analysis of Behavior, 58(1), 205–228. Ellis, E. M., Ala'i-Rosales, S. S., Glenn, S. S., Rosales-Ruiz, J., & Greenspoon, J. (2006). The effects of graduated exposure, modeling, and contingent social attention on tolerance to skin care products with two children with autism. Research in Developmental Disabilities, 27(6), 585–598. Halbur, M., Kodak, T., McKee, M., Carroll, R., Preas, E., Reidy, J., & Cordeiro, M. C. (2021). Tolerance of face coverings for children with autism spectrum disorder. Journal of Applied Behavior Analysis, 54(2), 600-617. Richling, S. M., Rapp, J. T., Carroll, R. A., Smith, J. N., Nystedt, A., & Siewert, B. (2011). Using noncontingent reinforcement to increase compliance with wearing prescription prostheses. Journal of Applied Behavior Analysis, 44(2), 375-379. Stark, L. J., Allen, K. D., Hurst, M., Nash, D. A., Rigney, B., & Stokes, T. F. (1989). Distraction: Its utilization and efficacy with children undergoing dental treatment. Journal of Applied Behavior Analysis, 22(3), 297-307. About the Guests Dr. Catherine (Katie) McHugh – Researcher focused on health-related routines and intervention strategies for adults with disabilities. Dr. Claudia Dozier – Expert in reinforcement schedules and their applications across populations. Dr. John Barrero – Current JABA Editor-in-Chief and behavior analyst contributing to dissemination and accessibility of applied research.
Who is it we are serving when we start or work in the coffee shop? If you listen to a lot of the way people talk today, you might think we expect customers to serve our needs more than we pursue meeting the needs of and serving our customers. Today on Shift Break we will be talking about the trend of backwards hospitality that has greatly diminished the hospitality experience across cafes and what we can do to bring our priorities back in line with what tru service and hospitality means. Here are some related episodes to explore: SHIFT BREAK! Why The Best Hospitality Starts With The Transactional! 532: Start with Hospitality 469: Unremarkable Hospitality and Cafe Terroir 430 : Embracing “Unreasonable Hospitality” w/ Will Guidara | Thank You NYC + The Welcome Conference 424: Developing Menu and Hospitality Guides APPLY NOW TO KEY HOLDER COACHING GROUPS! Are you a coffee shop owner looking to join a community of other owners to help bring perspective, insight, encouragement, and accountability in a well curated setting? Then you need to apply to join Key holder Coaching Groups! Applications are now open for fall 2025 Cohort: Click below to learn more: APPLY TO KEY HOLDER COACHING GROUPS HIRE KTTS CONSULTING AND COACHING! If you are a cafe owner and want to work one on one with me to bring your shop to its next level and help bring you joy and freedom in the process then email chris@keystothshop.com of book a free call now: https://calendly.com/chrisdeferio/30min Thank you to out sponsors! Everything you need for back of the house operations https://rattleware.qualitybystainless.com/ The best and most revered espresso machines on the planet: www.lamarzoccousa.com
Ever wondered if you're treating too many patients — or not enough?In this episode, we walk through Nicole's own journey, from solopreneur to running a 7-clinician practice. At each stage, her responsibilities and patient hours shifted. We (painfully) discuss the mistakes we made, what we'd do differently, and the myths that can trip up business owners.We cover:The trade-offs of maxing out your patient schedule as a solopreneur.The real math behind revenue when you're the only clinician.How to reassess your hours as you bring on staff.The biggest myth: that your clinicians won't respect you if you're not fully booked yourself.Why protecting your time is essential as your business (and life) grows.Whether you're a solopreneur seeing every patient or running a multi-clinician practice, this episode helps you rethink your hours and align your schedule with your goals.
In this episode, Ceri asks - Do you really need a commercial gallery to thrive as an artist? - The answer is no, not necessarily. Instead of relying solely on a commercial gallery, you need a team - a constellation of supporters, a circle of artistic champions. People who open doors, amplify your voice, provide feedback and help build momentum around your practice. Listen in to learn the basics of how to build an art world network that will transform your career. Then, if you like what you hear, sign up for Ceri´s Unlock Your Artworld Network Self Study Course to access a straightforward 5-step framework that will enable you build valuable relationships effortlessly. Gain the tools and confidence you need to create new opportunities and thrive in the art world today. https://cerihand.com/courses/unlock_your_artworld_network KEY TAKEAWAYS A successful art career relies on a diverse team of curators, producers, commissioners, writers, collectors, mentors, peers, and supporters. Each plays a unique role in amplifying your work, providing opportunities, and sustaining your creative growth. Don´t wait to be discovered. Proactively build relationships by reaching out with clarity, confidence, and genuine interest. Focus on nurturing diverse, reciprocal connections rooted in authenticity and care, rather than relying on a single gatekeeper. BEST MOMENTS “A thriving art career isn't built on one person saying yes, it's built on many people believing in your work, advocating for you and helping you to grow.” “Aim to build and nurture at least 10 meaningful relationships across this ecosystem and make it your mission to plug into at least two supportive networks every single year.” “This is about taking ownership, making your own map, and choosing connection over passivity.” PODCAST HOST BIO With over 35 years in the art world, Ceri has worked closely with leading artists and arts professionals, managed public and private galleries and charities, and curated more than 250 exhibitions and events. She sold artworks to major museums and private collectors and commissioned thousands of works across diverse media, from renowned artists such as John Akomfrah, Pipilotti Rist, Rafael Lozano-Hemmer and Vito Acconci. Now, she wants to share her extensive knowledge with you, so you can excel and achieve your goals. **** The Artist Mastermind Circle: Ready to stop second-guessing and start building momentum in your art career? Applications are now open for the next Artist Mastermind Circle—a six-month coaching programme for mid-career artists who are serious about growing their confidence, income, and opportunities. Apply by September 15th, 2025, at https://cerihand.com/artist-mastermind-circle and take the next bold step. Ceri Hand Coaching Membership: Group coaching, live art surgeries, exclusive masterclasses, portfolio reviews, weekly challenges. Access our library of content and resource hub anytime and enjoy special discounts within a vibrant community of peers and professionals. Ready to transform your art career? Join today! https://cerihand.com/membership **** Book a Discovery Call Today To schedule a personalised 1-2-1 coaching session with Ceri or explore our group coaching options, simply email us at hello@cerihand.com **** Discover Your Extraordinary Creativity Visit www.cerihand.com to learn how we can help you become an extraordinary creative. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk
Today, Ceri is joined by the brilliant and boundary-breaking Pari Ehsan, artist, curator and founder of the platform Pari Dust. She weaves transcultural aesthetics, fashion, architecture and contemporary art into rich, immersive images and experiences. A former architect and polymathic image maker, she has collaborated with institutions like MoMA, Tate Modern and brands like Chanel and Loewe. KEY TAKEAWAYS Pari shows us how intuition can be a research method and how beauty, far from being frivolous, is a site of inquiry, emotion and connection. There's a generosity in Pari´s way of working, a desire not just to witness but to translate, to honour the artists she engages with, while also inviting new audiences in. Artists often undervalue their take on the world, their knowledge. The value is not just in the finished work; it's in the research and the curiosity adventures the artist goes on to create it. BEST MOMENTS “Let Pari's work be a provocation to get closer, to stay curious, to make your own strange and luminous mark on the world.” "The idea that beauty is that cookie cutter image or something that really can be replicated, I don't think that's true. Beauty can come in moments and disappear, it´s ephemeral." “It's possible to create work that is both emotionally resonant and intellectually sharp. Care can be your compass, even when you're breaking new ground.” EPISODE RESOURCES https://www.paridust.com https://www.instagram.com/paridust https://www.tiktok.com/@paridust HOST BIO With over 35 years in the art world, Ceri has worked closely with leading artists and arts professionals, managed public and private galleries and charities, and curated more than 250 exhibitions and events. She sold artworks to major museums and private collectors and commissioned thousands of works across diverse media, from renowned artists such as John Akomfrah, Pipilotti Rist, Rafael Lozano-Hemmer and Vito Acconci. Now, she wants to share her extensive knowledge with you, so you can excel and achieve your goals. **** The Artist Mastermind Circle: Ready to stop second-guessing and start building momentum in your art career? Applications are now open for the next Artist Mastermind Circle—a six-month coaching programme for mid-career artists who are serious about growing their confidence, income, and opportunities. Apply by September 15th, 2025, at https://cerihand.com/artist-mastermind-circle and take the next bold step. Ceri Hand Coaching Membership: Group coaching, live art surgeries, exclusive masterclasses, portfolio reviews, weekly challenges. Access our library of content and resource hub anytime and enjoy special discounts within a vibrant community of peers and professionals. Ready to transform your art career? Join today! https://cerihand.com/membership **** Unlock Your Artworld Network Self Study Course Our self-study video course, "Unlock Your Artworld Network," offers a straightforward 5-step framework to help you build valuable relationships effortlessly. Gain the tools and confidence you need to create new opportunities and thrive in the art world today. https://cerihand.com/courses/unlock_your_artworld_network **** Book a Discovery Call Today To schedule a personalised 1-2-1 coaching session with Ceri or explore our group coaching options, simply email us at hello@cerihand.com **** Discover Your Extraordinary Creativity Visit www.cerihand.com to learn how we can help you become an extraordinary creative. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk
Dave speaks with Anna Bellini, an alum of the Coaching for Leaders Academy, on how to stop a behavior in order to move forward. Applications to the Coaching for Leaders Academy will open the first week of September. Visit the Academy page to request an early invitation.
See More: https://thinkfuture.substack.comConnect With Sam: https://www.linkedin.com/in/sam-bigdeli-5310b923/---Why the next wave of AI won't just answer questions—it will explore, sense, and predict.In this episode of thinkfuture, host Chris Kalaboukis talks with Sam Bigdeli, co-founder and CEO of KavAI, about his vision for Curious AI—a new approach that moves beyond language models to create AI that actively engages with the physical world.Sam explains why today's AI systems are like “savants”—brilliant at data recall, but poor at contextual reasoning. Curious AI, on the other hand, is designed to simulate the way humans explore, hypothesize, and learn from limited sensory input.We cover:- Why large language models (LLMs) aren't enough for real-world intelligence- The importance of embodiment and multimodal sensing for AI systems- How Curious AI actively acquires information instead of waiting to be prompted- Applications in industrial domains like refineries, power plants, and predictive maintenance- The future of AI and robotics—human-like avatars vs. task-optimized systems- Why human creativity and judgment will always remain essentialSam envisions a future where AI isn't just reactive—it's proactive, curious, and capable of helping us manage complex, dynamic systems more effectively.If you're interested in the cutting edge of AI, robotics, and the future of human-machine collaboration, this is an episode you won't want to miss.
Like Pepsi in 1984, coffee is the "Choice of a New Generation"... but maybe not in the same way as we of older generations are comfortable with. The ways digital natives are consuming coffee today may be unique, but as with all coffee consumers before and after, they are seeking the identity, belonging, utility, and promises associated with coffee and the community it has always facilitated. The question we need to ask is how do we in the world f coffee shops acknowledge, welcome, include, adn understand these very important consumers? To help us explore this we are chatting with friend of the show and deep thinker extraordinaire, Kosta Kallivrousis! Kosta Kallivrousis has spent over 14 years working across the specialty-coffee supply chain. His unique combination of experience as a barista, licensed Q grader, and in strategic sales at both roasted and green coffee companies has given him a 360°-view of the specialty-coffee world. Kosta is passionate about building equitable sourcing relationships between coffee producers and buyers, challenging industry norms around taste and value, and advocating for greater connection and community in the coffee industry. Links: KOSTA ON INSTAGRAM: https://www.instagram.com/espresso_patronus/ Other Links: The barista mag piece Kosta wrote about cafe raves The death of a millennial brand with Euguene Healey Postmillennials desire era's and not fixed identities by Eugene Healey How Gen Z expects brands to interact with them by Ogilvy. Related episodes: 321 : Marketing and Moral Injury w/ Josh Tarlo of Kiss the Hippo 393 : The Tyranny of Taste w/ Kosta Kallivrousis SHIFT BREAK: Quality Still Matters Some Tips on Signature Drinks Menu Simplicity as Hospitality 274 : Crafting Specialty Drinks in your Shop w/ Matt Foster” 548: Cool Ideas For Customer Engagement Insights into the specialty coffee industry and its challenges. KEY HOLDER COACHING GROUPS! Are you a coffee shop owner looking to join a community of other owners to help bring perspective, insight, encouragement, and accountability in a well curated setting? Then you need to apply to join Key holder Coaching Groups! Applications are now open for fall 2025 Cohort: Click below to learn more: APPLY TO KEY HOLDER COACHING GROUPS KEYS TO THE SHOP ALSO OFFERS 1:1 CONSULTING AND COACHING! If you are a cafe owner and want to work one on one with me to bring your shop to its next level and help bring you joy and freedom in the process then email chris@keystothshop.com of book a free call now: https://calendly.com/chrisdeferio/30min SPONSORS Want a beautiful coffee shop? All your hard surface, stone, Tile and brick needs! www.arto.com Visit @artobrick The world loves plant based beverages and baristas love the Barista Series! www.pacificfoodservice.com
Mariano founded Onapsis back in 2009 to address the challenges securing a growing new class of technology: ERP systems. After working at CYBSEC for 5 years doing offensive security research, he discovered just how vulnerable SAP applications could be. Onapsis is sneakily a juggernaut, having raised a $55 million Series D in 2020. And while they started focused on SAP, they have since expanded into related tools such as Oracle. They have certainly established themselves as core to securing an often overlooked component of IT infrastructure. In the conversation we discuss the founding story, why SAP couldn't do this themselves, and how he has thought about growth opportunities over the last 16 years.Website
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In this episode of the Work Matters Podcast, host Thomas Bertels and Patrick Farran talk about the power of co-creation. The conversation highlights the importance of involving team members in decision-making processes for significant change initiatives, because people value what they help create. Patrick explains the benefits and challenges of a co-creation approach and provides scenarios where co-creation is effective, such as strategic planning and job crafting, and cautions against performative co-creation. The discussion also touches on appreciative inquiry, the necessity for psychological safety, and the mindset shifts required for leaders to successfully implement co-creation. Patrick shares practical tips for leaders to start small with everyday interactions, ensuring clarity of processes and fostering an environment of constructive conflict and collaboration. 00:00 Introduction to Co-Creation00:59 Defining Co-Creation01:49 Pros and Cons of Co-Creation04:39 Examples and Applications of Co-Creation06:18 Challenges and Leadership Mindset10:09 Appreciative Inquiry and Co-Creation11:35 Getting Started with Co-Creation14:52 Prerequisites for Successful Co-Creation25:13 Final Thoughts Use these links to connect and learn more about Patrick and his upcoming book, 'The Intentional Executive,' which aims to guide leaders in being more intentional and effective in their roles. LinkedIn: https://www.linkedin.com/in/patrickfarran/Website: http://www.adlucemgroup.comBook: https://adlucemgroup.com/the-intentional-executive-prelaunch/
Expand with Gabrielle: Manifestation and Spiritual Boss Babes
In this hot-seat coaching episode, I sit down with spiritual entrepreneur Sarah Scully-Leaf to dive into the behind-the-scenes reality of building a soul-led business. Together, we unpack the challenges of launching multiple offers, finding clarity in your message, and scaling your business in a way that honors both Strategy and Self.You'll hear us explore: ✨ How to weave together diverse modalities like somatics, breathwork, and subconscious rewiring under one powerful brand umbrella. ✨ The balance between marketing strategy and nervous system regulation, so you can scale to six-figures without burnout. ✨ Why leading with desire (the “chocolate”) over modalities (the “broccoli”) creates magnetic messaging that attracts soul-aligned clients. ✨ Practical tips for simplifying launches, speaking to your ideal client's subconscious mind, and moving past limiting beliefs around visibility and money.If you're a spiritual business owner or soul-led entrepreneur who desires to merge business strategy, embodiment, and money energetics, this episode will show you how to become magnetic, manifest abundance, and create a feminine-friendly business that supports your lifestyle and impact.Work with Sarah: you can find her course Health that Holds here https://www.sarahscullyleaf.com/hth use code: GABS10 and get 10% off----The Booked-Out Business Blueprint:https://gabriellemartorana.com/blueprintHave you been pouring your heart into growing your business to six figures... but still missing the mark?What bridges that gap? The powerful fusion of Self and Strategy.Inside The School of Expansion, we blend subconscious rewiring, sacred business strategy, and nervous system alignment, so your business scales with your energy, not depletes it.Applications are open now for the Sept 2025 cohort. Head to gabriellemartorana.com/TSOE to apply.Want to go deeper? Apply for The School of Expansion - www.gabriellemartorana.com/TSOE Send me a DM & let me know you tuned into the episode, I would love to hear from you - www.instagram.com/expandwithgabrielle
Sometimes the fossil record preserves some really astonishing traces of past life, including footprints and even burrows! But how can there be burrows if the fossil record were formed by a singular, catastrophic flood? Leonard Brand wondered this very same question and set out to try to understand how much of a problem this really is. Todd and Paul chat with him about his research on fossil burrows and learn the shocking reality of the fossil record. There just aren't that many burrows at all! What does this mean for the flood or for long age geology? Find out in this latest episode of Let's Talk Creation! #creationism #creationscienceMaterials mentioned in this episodeBrand, Leonard and Art Chadwick. Faith, Reason, and Earth History:A Paradigm of Earth and Biological Origins by Intelligent Design, 3rd edition. 2016Hardcover: https://a.co/d/2VodNGjFree EPUB: https://cdn.ministerialassociation.org/cdn/eldersdigest.org/files/Faith,%20Reason,%20and%20Earth%20History%20by%20Leonard%20Brand%20and%20Arthur%20Chadwick.pdf Östring , Sven. Rising Waters, Enduring Faith: Investigating the Historical & Global Reality of the Biblical Flood. 2025.https://a.co/d/3IQcdAz Bromley RG. Trace Fossils: Biology, Taphonomy and Applications. 3rd ed. London: Chapman and Hall; 1996. https://archive.org/details/tracefossilsbiol0000brom
Today's guest is Jon Peppers, Principal Software Engineer on the .NET MAUI team at Microsoft. Before building developer tools, Jonathan was a Xamarin MVP and the lead developer behind various cross-platform Maui apps. With a deep background in C#, from WPF-based self-checkout systems to home automation software featured on Extreme Home Makeover, Jonathan brings a wealth of experience in both app development and the frameworks that power them. Topics of Discussion: [1:59] Jonathan recounts his first job after college, working on C# for self-checkout software and migrating to WPF. [4:40] How much on the continuum are we right now with Copilot agent mode? [7:11] The process of setting up Maui development, including installing Visual Studio and the Maui workload. [12:40] Using Copilot for multi-language debugging. [18:42] Copilot's effectiveness in deleting unnecessary files and finding errors in string localization files. [19:10] Copilot coding agent. [21:20] The process of assigning issues to Copilot, which creates a branch, opens a pull request, and updates the description with its plan. [27:36] The availability of different models in VS Code, including Claude and GPT, and the anticipation of new models being released. [31:36] The potential for using LLMs on-device for privacy concerns, especially in healthcare. [35:01] Jonathan encourages developers to try Copilot in their IDEs and explore its code completions and suggestions. [35:17] Jonathan's Cat Swipe dating site! Mentioned in this Episode: Clear Measure Way Architect Forum Software Engineer Forum How the .NET Maui Team uses GitHub Copilot for Productivity Jonathan on LinkedIn Jonathan Peppers Want to Learn More? Visit AzureDevOps.Show for show notes and additional episodes.
'I don't think that Labour care to fix the problem.'Independent journalist Jack Hadfield doesn't believe the Government has any interest in tackling the migrant crisis. Hosted on Acast. See acast.com/privacy for more information.
Once again it is Founder Friday! The world of coffee encompasses vast regions of taste and culture, all united by the communal cup of coffee. In the Philippines there has been an incredible movement of specialty. Yardstick Coffee stands as one of the original specialty coffee roasters and retailers that has built a solid and growing company that continually pursues new ways to serve people through services of wholesale, roasting, equipment, and more. Today we are going to be talking with one of the founders of Yardstick Coffee, Andre Chanco! Andre Chanco began his career in IT, working as a consultant for a multinational company before making an unexpected pivot to coffee. While working part-time at Papa Palheta—one of Singapore's pioneering specialty coffee roasters—he immersed himself in coffee roasting, eventually becoming a full-time apprentice. Over the years, he took on responsibilities in green buying and marketing, setting the foundation for his future in coffee. In 2013, Andre co-founded Yardstick Coffee in Manila with university friends Kevin and Jessica. What began as a wholesale roasting and equipment business has since evolved into one of the Philippines' leading specialty coffee brands. Today, Andre serves as Head of Product and Brand, overseeing green coffee sourcing and the company's product development. Founded in 2013, Yardstick began as a B2B coffee roaster and equipment distributor, becoming the official partner of La Marzocco and Rocket Espresso in the Philippines. With just one showroom and training space in Makati, Yardstick offered coffee roasting, SCA certification workshops, and equipment solutions for cafes and restaurants. Following the pandemic, Yardstick shifted its focus to retail, evolving into a customer-led, community-driven coffee brand. Today, Yardstick operates nine stores across Metro Manila, with plans to open two more by the end of 2025. The company continues to roast specialty coffee in-house, with a strong emphasis on quality, accessibility and discovery. Yardstick has also proudly hosted the Philippine AeroPress Championship for over a decade, championing accessibility, collaboration, and growth in the local coffee scene. I hope you enjoy this conversation that takes you all the way from the founding of Yardstick, into the inner workings of their organization, management and philosophies- to today and what their focus is to continue to deliver exceptional experiences in all areas of the company. Links: https://store.yardstickcoffee.com/ http://www.drinkmorning.com/ http://www.standardsupplystudios.com/ https://www.instagram.com/yardstickcoffee/ Related episodes: Special! “Thinking Differently” Series | Filipino Coffee w/ Ron Dizon of Teofilo Coffee! 310 : Founder Friday w/ Jelynn Malone and Beverly Magtanong of Mostra Coffee 188 : Founder Friday w/ Jon Allen of Onyx Coffee Lab Insights into the specialty coffee industry and its challenges. KEY HOLDER COACHING GROUPS! Are you a coffee shop owner looking to join a community of other owners to help bring perspective, insight, encouragement, and accountability in a well curated setting? Then you need to apply to join Key holder Coaching Groups! Applications are now open for fall 2025 Cohort: Click below to learn more: APPLY TO KEY HOLDER COACHING GROUPS KEYS TO THE SHOP ALSO OFFERS 1:1 CONSULTING AND COACHING! If you are a cafe owner and want to work one on one with me to bring your shop to its next level and help bring you joy and freedom in the process then email chris@keystothshop.com of book a free call now: https://calendly.com/chrisdeferio/30min SPONSORS Want a beautiful coffee shop? All your hard surface, stone, Tile and brick needs! www.arto.com Visit @artobrick The world loves plant based beverages and baristas love the Barista Series! www.pacificfoodservice.com
Broadcast from KSQD, Santa Cruz on 8-21-2025: Dr. Dawn opens with disturbing research linking respiratory infections to breast cancer reactivation. Studies show increased breast cancer deaths during COVID beyond screening delays, suggesting viral infections may awaken dormant cancer cells through inflammatory signals. Mouse models demonstrate that influenza infection can increase metastatic burden up to 1000-fold by triggering neutrophil extracellular traps that act as growth signals for sleeping cancer cells. She covers neuroimmune crosstalk in lung fibrosis research, where mice lacking pain receptors developed worse scarring when exposed to lung injury. The absence of pain signals failed to trigger natural inflammation suppressors, leading to increased neutrophil activity and inflammatory nets that contributed to tissue damage. New food spoilage detection technology uses pH-sensitive dyes in packaging that fluoresce or change color when bacterial metabolism produces acids. This could prevent foodborne illness from contaminated deli meats and dairy products by providing visual warnings before consumption, particularly important for high-risk foods like lunch meats and mayonnaise. Dr. Dawn warns about diquat replacing glyphosate in Roundup products, potentially creating 200 times more toxicity. The new compound suppresses gut lining proteins, creating leaky gut and allowing bacterial toxins into the bloodstream, while causing permanent kidney, liver, and lung damage. Most countries have banned diquat, but it remains available in American stores. Research reveals that lactose intolerance can cause intense nightmares through gut-brain connections. Montreal studies found that people with dairy sensitivity experience more frequent, distressing dreams that improve significantly when dairy is eliminated from their diet. The mechanism likely involves gastrointestinal discomfort causing microarousals that make dreams more vivid and memorable. She describes revolutionary remote-controlled probiotics combining genetically modified E. coli with pill cameras. These bacterial robots can detect inflammation, produce therapeutic compounds on command, and communicate through bioluminescence. Applications include targeted inflammatory bowel disease treatment where bacteria manufacture anti-TNF nanobodies when activated by LED signals from swallowed capsules. An emailer with recurring diverticulitis asks about surgical options versus dietary management. Dr. Dawn explains the structural causes of diverticular disease and the vicious cycle created by repeated antibiotic treatments that damage gut microbiomes. She emphasizes the importance of dramatically increasing fiber intake and addressing underlying leaky gut issues that may contribute to the condition. A caller asks about foods for better bowel movements while managing diabetes and taking Wegovy. Dr. Dawn recommends ground flaxseed mixed into various foods and weekly preparation of roasted root vegetables for someone with limited cooking skills. The conversation becomes personal as the caller expresses concerns about housing security and healthcare access during uncertain political times. New microplastic research reveals how these particles accumulate bacteria, viruses, and toxins in biofilm "coronas" that enhance their harmful effects. Different plastic types carry varying electric charges affecting where they travel in the body. Breakthrough laser detection methods now allow precise identification and tracking of specific plastic polymers in tissues, enabling better research on health impacts. Dr. Dawn discusses advances in CAR-T cell therapy for multiple myeloma, sharing positive results from her husband's recent treatment. New research suggests injecting lipid nanoparticles containing CAR DNA instead of removing T-cells for laboratory modification, potentially making this therapy much cheaper and more accessible while maintaining effectiveness for blood cancers.
Welcome back to another jam-packed episode of Tank Talks! Host Matt Cohen is joined by John Ruffolo to break down the biggest headlines shaping Canada's business, tech, and financial future. From the $12.3B privatization of Dayforce, to the Canadian government's long-overdue embrace of AI startups, and the urgent debate over stablecoins and financial sovereignty, this episode dives deep into the forces reshaping Canada's economy.Whether you're a founder, investor, or policy watcher, you don't want to miss this candid conversation on where Canada is winning and where we risk falling dangerously behind.Dayforce Acquired in $12.3B Mega Sale (01:15)Matt and John unpack Thoma Bravo's $12.3 billion acquisition of Dayforce, Canada's largest private tech buyout in history. They discuss why HR software has become a hot consolidation market, the risks of Canadian management talent shifting south, and what this deal signals for the future of SaaS valuations.The Rise of Tender Offers & Canva's $42B Valuation (06:01)With Canva's latest employee tender round oversubscribed, John and Matt explore why private markets remain so frothy, how valuation gaps compare to IPOs like Figma's, and what it means for Canadian scale-ups eyeing liquidity.AI Funding Frenzy: Cohere's $500M Raise & Government Partnership (07:30)Canadian AI champion Cohere announced a $500M round at a $6.8B valuation and a landmark MOU with the federal government. John and Matt debate whether government procurement can finally support Canadian AI companies and if AI cost curves are sustainable as token prices plummet.The AI Economics Debate: Infrastructure vs. Applications (10:05)With LLM costs dropping and cloud providers cashing in, John and Matt analyze whether the money in AI will flow to infrastructure giants like Nvidia and Microsoft, or to niche application-layer startups battling against the incumbents.Google's AI Energy Report & The Sustainability Question (13:24)Google claims its Gemini models are 33x more efficient than last year. John questions whether those numbers hold up at scale and what AI's true carbon footprint means for global adoption.China's Stablecoin Push & The Threat to Canadian Sovereignty (15:14)China moves toward approving yuan-backed stablecoins, while the US doubles down on dollar-backed alternatives. John warns that Canada's silence on stablecoin policy risks losing monetary sovereignty, while Matt predicts US dollar stablecoins could eclipse the Canadian dollar within a decade.Why Canadian Entrepreneurs Need “Team Canada” Capital (21:06)Drawing from his recent Substack essay, Chasing the Tornado, John argues that Canada's biggest risk is capital providers sitting on the sidelines. He calls for pensions, banks, and family offices to invest in sovereign businesses before Canada loses control of key industries.Walking Again with AI-Powered Robotics (23:47)On a personal note, John shares his inspiring first steps in a robotic exoskeleton built by Human in Motion Robotics. He describes how AI-driven rehab tech could transform mobility for millions and why this Canadian innovation deserves global attention.Connect with John Ruffolo on LinkedIn: https://ca.linkedin.com/in/joruffoloConnect with Matt Cohen on LinkedIn: https://ca.linkedin.com/in/matt-cohen1Visit the Ripple Ventures website: https://www.rippleventures.com/ This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit tanktalks.substack.com
- Announcement of Enoch AI Engine Upgrade (0:03) - Accessing Enoch AI Engine (2:29) - Prompt Engineering and Use Cases (4:59) - Challenges and Successes in Training Enoch (9:25) - Applications and Benefits of Enoch AI Engine (12:21) - Demonstration and Comparison with Other AI Engines (18:10) - Support and Future Plans (1:06:27) - Enoch's Impact on Independent Media (1:17:07) - Conclusion and Call to Action (1:17:27) For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com
Dave speaks with Mel Rivera, an alum of the Coaching for Leaders Academy, on how she built visibility for her team. Applications to the Coaching for Leaders Academy will open the first week of September. Visit the Academy page to request an early invitation.
Melissa and Jam delve into the fascinating chemistry behind fireflies' bioluminescence. They explore how fireflies produce light through a complex series of chemical reactions involving specific molecules like luciferin and enzymes like luciferase. The discussion extends to how these mechanisms find applications in scientific research, such as identifying tumors in mice. The episode is interspersed with nostalgic summer stories, making it a blend of chemistry education and personal anecdotes. 00:00 Nostalgic Summer Evenings 00:33 Fireflies and Childhood Wonder 01:04 Introduction to Firefly Chemistry 02:22 Shoutout to Ash and Podcast Tips 03:58 Diving into Bioluminescence 04:52 The Chemistry Behind Firefly Light 11:17 Understanding Acid-Base Reactions 16:13 The Role of Luciferase 18:43 The Unstable Four-Membered Ring 28:39 Understanding Molecular Structures 29:33 The Instability of Molecular Rings 33:39 Fireflies and Bioluminescence 40:53 Applications in Medical Science 45:37 Nostalgic Summer Memories 52:48 Supporting the Show and Final Thoughts ★ Support this podcast on Patreon ★ ★ Buy Podcast Merch and Apparel ★ Check out our website at chemforyourlife.com Watch our episodes on YouTube Find us on Instagram, Twitter, and Facebook @ChemForYourLife References from this episode: https://www.chemistryworld.com/podcasts/luciferin/3005839.article https://www.science.org/content/article/watch-chemistry-behind-how-fireflies-glow https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.113.258103 https://youtu.be/pTPMwZK2-yM https://pubs.acs.org/doi/10.1021/jacs.5b03820 https://pubs-acs-org.libproxy.library.unt.edu/doi/10.1021/jp301910p https://chemistry-europe-onlinelibrary-wiley-com.libproxy.library.unt.edu/doi/10.1002/cphc.201300330 https://chemistry-europe-onlinelibrary-wiley-com.libproxy.library.unt.edu/doi/10.1002/cphc.201200195 https://iubmb-onlinelibrary-wiley-com.libproxy.library.unt.edu/doi/10.1002/iub.134 https://chemistry-europe-onlinelibrary-wiley-com.libproxy.library.unt.edu/doi/10.1002/cbic.200500443 https://www.chemistryworld.com/news/rainbow-makers/3003381.article https://www.acs.org/molecule-of-the-week/archive/f/firefly-luciferin.html Thanks to our monthly supporters Kyle McCray Justine Emily Hardy Ash Vince W Julie S. Heather Ragusa Autoclave Chelsea Morelos Dorien VD Scott Beyer Jessie Reder Ciara Linville J0HNTR0Y Jeannette Napoleon Cullyn R Erica Bee Elizabeth P Rachel Reina Letila Katrina Barnum-Huckins Suzanne Phillips Venus Rebholz Lyn Stubblefield Jacob Taber Brian Kimball Kristina Gotfredsen Timothy Parker Steven Boyles Chris Skupien Chelsea B Avishai Barnoy Hunter Reardon ★ Support this podcast on Patreon ★ ★ Buy Podcast Merch and Apparel ★ Check out our website at chemforyourlife.com Watch our episodes on YouTube Find us on Instagram, Twitter, and Facebook @ChemForYourLife
Where are you wasting money in your business — and where are you not investing enough?In this episode, we break down the biggest money mistakes we see pelvic business owners make. Spoiler: it's not about whether something feels “expensive,” it's about Return on Investment (ROI).
From catchment areas to sibling rules, school applications are no joke. This week, Emma and Soph unpack the chaos of applying for primary and secondary schools, including house moves, catchment confusion, and what really matters on the application. Plus, your back-to-school tips on uniform shopping, Mufti Day money, and why a playdate might just be the secret weapon every mum needs. Hosted on Acast. See acast.com/privacy for more information.
A new law went into effect recently that's intended to make recycling easier statewide, but it means the rules here in Portland are changing yet again. Today we're talking with Metro's Waste Prevention outreach manager, Jennifer Powers, for tips. She'll explain why our recycling rules are so finicky, help break down the new rules, and also let us know what you now can — and can't — recycle here in Portland. Mentioned in today's episode: Recycling – What Goes in the Bin [Portland.gov] Recycle or Not [Instagram] Metro Recycling Information Center (Ask an Expert): 503-234-3000 City Cast Portland is hiring a social media manager! If you have experience creating incredible social content, and want to help make your neighbors more engaged and informed, we'd love to hear from you. Applications are due August 22nd — find more information and apply here. Become a member of City Cast Portland today! Get all the details and sign up here. Who would you like to hear on City Cast Portland? Shoot us an email at portland@citycast.fm, or leave us a voicemail at 503-208-5448. Want more Portland news? Then make sure to sign up for our morning newsletter, Hey Portland, and be sure to follow us on Instagram. Looking to advertise on City Cast Portland? Check out our options for podcast and newsletter ads at citycast.fm/advertise. Learn more about the sponsors of this August 21st episode: Montavilla Jazz PaintCare Oregon Health Authority Visit Walla Walla Oregon Coast Visitor Association - Use code 50off for 50% off Purchase Your NW Natural Street of Dreams here!
Hi friends! We're taking a much-needed August pause—we'll have new episodes for you in September. In the meanwhile, enjoy this pick from our archives! _____ [originally aired February 8, 2024] Where do memories live in the brain? If you've ever taken a neuroscience class, you probably learned that they're stored in our synapses, in the connections between our neurons. The basic idea is that, whenever we have an experience, the neurons involved fire together in time, and the synaptic connections between them get stronger. In this way, our memories for those experiences become minutely etched into our brains. This is what might be called the synaptic view of memory—it's the story you'll find in textbooks, and it's often treated as settled fact. But some reject this account entirely. The real storehouses of memory, they argue, lie elsewhere. My guest today is Dr. Sam Gershman. Sam is Professor of Psychology at Harvard University, and the director of the Computational Cognitive Neuroscience Lab there. In a recent paper, he marshals a wide-ranging critique of the synaptic view. He makes a compelling case that synapses can't be the whole story—that we also have to look inside the neurons themselves. Here, Sam and I first discuss the synaptic view and the evidence that seems to support it. We then talk about some of the problems with this classic picture. We consider, for example, cases where memories survive the radical destruction of synapses; and, more provocatively, cases where memories are formed in single-celled organisms that lack synapses altogether. We talk about the dissenting view, long lurking in the margins, that intracellular molecules like RNA could be the real storage sites of memory. Finally, we talk about Sam's new account—a synthesis that posits a role for both synapses and molecules. Along the way we touch on planaria and paramecia; spike-timing dependent plasticity; the patient H.M.; metamorphosis, hibernation, and memory transfer; the pioneering work of Beatrice Gelber; unfairly maligned ideas; and much, much more. Before we get to it, one important announcement: Applications are now open for the 2024 Diverse Intelligences Summer Institute (or DISI)! The event will be held in beautiful, seaside St Andrews, Scotland, from June 30 to July 20. If you like this show—if you like the conversations we have and the questions we ask—it's a safe bet that you'd like DISI. You can find more info at disi.org—that's disi.org. Review of applications will begin on Mar 1, so don't delay. Alright friends, on to my conversation about the biological basis of memory with Dr. Sam Gershman. Enjoy! Notes and links 4:00 - A general audience article on planarian memory transfer experiments and the scientist who conducted them, James V. McConnell. 8:00 - For more on Dr. Gershman's research and general approach, see his recent book and the publications on his lab website. 9:30 - A brief video explaining long-term potentiation. An overview of “Hebbian Learning.” The phrase “neurons that fire together wire together” was, contrary to widespread misattribution, coined by Dr. Carla Shatz here. 12:30 - The webpage of Dr. Jeremy Gunawardena, Associate Professor of Systems Biology at Harvard University. A recent paper from Dr. Gunawardena's lab on the avoidance behaviors exhibited by the single-celled organism Stentor (which vindicates some disputed, century-old findings). 14:00 - A recent paper by C. R. Gallistel describing some of his views on the biological basis of memory. 19:00 - The term “engram” refers to the physical trace of a memory. See recent reviews about the so-called search for the engram here, here, and here. 20:00 - An article on the importance of H.M. in neuroscience. 28:00 - A review about the phenomenon of spike-timing dependent plasticity. 33:00 - An article, co-authored by former guest Dr. Michael Levin, on the evidence for memory persistence despite radical remodeling of brain structures. See our episode with Dr. Levin here. 35:00 - A study reporting the persistence of memories in decapitated planarians. A popular article about these findings. 36:30 - An article reviewing one chapter in the memory transfer history. Another article reviewing evidence for “vertical” memory transfer (between generations). 39:00 - For more recent demonstrations of memory transfer, see here and here. 40:00 - A paper by Dr. Gershman, Dr. Gunawardena, and colleagues reconsidering the evidence for learning in single cells and describing the contributions of Dr. Beatrice Gelber. A general audience article about Gelber following the publication of the paper by Dr. Gershman and colleagues. 45:00 – A recent article arguing for the need to understand computation in single-celled organisms to understand how computation evolved more generally. 46:30 – Another study of classical conditioning in paramecia, led by Dr. Todd Hennessey. 49:00 – For more on plant signaling, see our recent episode with Dr. Paco Calvo and Dr. Natalie Lawrence. 56:00 – A recent article on “serial reversal learning” and its neuroscientific basis. 1:07:00 – A 2010 paper demonstrating a role for methylation in memory. Recommendations The Behavior of the Lower Organisms, by Herbert Spencer Jennings Memory and the Computational Brain, by C. R. Gallistel and Adam Philip King Wetware, by Dennis Bray Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the John Templeton Foundation to Indiana University. The show is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben Oldroyd. Our transcripts are created by Sarah Dopierala. Subscribe to Many Minds on Apple, Stitcher, Spotify, Pocket Casts, Google Play, or wherever you listen to podcasts. You can also now subscribe to the Many Minds newsletter here! We welcome your comments, questions, and suggestions. Feel free to email us at: manymindspodcast@gmail.com. For updates about the show, visit our website or follow us on Twitter (@ManyMindsPod) or Bluesky (@manymindspod.bsky.social).
Figures from the Home Office show that there were a record number of asylum applications made last year. Also: Teenagers in England, Wales and Northern Ireland open their GCSE and BTEC results. And the celebrity judge, Frank Caprio, has died at the age of 88.
Today, Ceri answers the age-old question – Do You Really Need a Commercial Gallery to Thrive as an Artist? Ceri has run her own commercial galleries in Liverpool and London, worked for the blue-chip Simon Lee Gallery, attended art fairs across the world, and sold work to major museums and private collectors—seen this industry from the inside out, so she has a lot to say on the subject, some of which may surprise you. KEY TAKEAWAYS Increasingly, insiders are walking away from their galleries, because the system has stopped making sense, including Tim Blum. Many successful artists start by being shown in artist-led spaces, having their work reviewed by independent art blogs and being active in studio groups, residencies and mentoring schemes. If you are already represented, ask your gallery what you can do to help both of you succeed. BEST MOMENTS “The honest truth, most artists don't actually know what a gallery does or what they need from you to make it work, or what it costs them and you.” “Within a year, she sold a piece to a regional museum collection through one of those curator connections. No big break, no golden ticket, just consistent, strategic, intentional action.” “If you're seeking representation, start with research. Which galleries feel aligned with your values and your voice?” Ep 49 - https://podcasts.apple.com/gb/podcast/an-artists-guide-to-working-with-commercial-art/id1709105337?i=1000664980028 PODCAST HOST BIO With over 35 years in the art world, Ceri has worked closely with leading artists and arts professionals, managed public and private galleries and charities, and curated more than 250 exhibitions and events. She sold artworks to major museums and private collectors and commissioned thousands of works across diverse media, from renowned artists such as John Akomfrah, Pipilotti Rist, Rafael Lozano-Hemmer and Vito Acconci. Now, she wants to share her extensive knowledge with you, so you can excel and achieve your goals. **** The Artist Mastermind Circle: Ready to stop second-guessing and start building momentum in your art career? Applications are now open for the next Artist Mastermind Circle—a six-month coaching programme for mid-career artists who are serious about growing their confidence, income, and opportunities. Apply by September 15th, 2025, at https://cerihand.com/artist-mastermind-circle and take the next bold step. Ceri Hand Coaching Membership: Group coaching, live art surgeries, exclusive masterclasses, portfolio reviews, weekly challenges. Access our library of content and resource hub anytime and enjoy special discounts within a vibrant community of peers and professionals. Ready to transform your art career? Join today! https://cerihand.com/membership **** Unlock Your Artworld Network Self Study Course Our self-study video course, "Unlock Your Artworld Network," offers a straightforward 5-step framework to help you build valuable relationships effortlessly. Gain the tools and confidence you need to create new opportunities and thrive in the art world today. https://cerihand.com/courses/unlock_your_artworld_network **** Book a Discovery Call Today To schedule a personalised 1-2-1 coaching session with Ceri or explore our group coaching options, simply email us at hello@cerihand.com **** Discover Your Extraordinary Creativity Visit www.cerihand.com to learn how we can help you become an extraordinary creative. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk
In forums, trade shows, and conversations everywhere, people are talking about their problems, and that's not a bad thing! The problem starts when the talk is not productive and starts to warp reality and damages our ability to work, serve and lead well due to the bitterness commiseration tends to produce. Today on Shift Break we will be talking about the problems that commiseration brings and how we can recognize and redirect the way we talk so we can be as objective as possible in how we see the world of positives and challenges that surround us. Here are some related episodes to explore: Gossip! Who You Are + What You Do APPLY NOW TO KEY HOLDER COACHING GROUPS! Are you a coffee shop owner looking to join a community of other owners to help bring perspective, insight, encouragement, and accountability in a well curated setting? Then you need to apply to join Key holder Coaching Groups! Applications are now open for fall 2025 Cohort: Click below to learn more: APPLY TO KEY HOLDER COACHING GROUPS HIRE KTTS CONSULTING AND COACHING! If you are a cafe owner and want to work one on one with me to bring your shop to its next level and help bring you joy and freedom in the process then email chris@keystothshop.com of book a free call now: https://calendly.com/chrisdeferio/30min Thank you to out sponsors! Everything you need for back of the house operations https://rattleware.qualitybystainless.com/ The best and most revered espresso machines on the planet: www.lamarzoccousa.com
Working harder doesn't always lead to better results.In fact, late nights and weekend grinds often just highlight broken systems - not progress.The difference between creatives who stay stuck and those who hit consistent $10k months? They're working hard on the right things.In this episode of the Creativ Rise Podcast, we break down 10 great business offers from 10 ambitious Mastermind grads - and we share the strategies behind how those offers are consistently generating $10k+ months (no ****gatekeeping here
Today, we're talking about the prospective sale of the Portland Trail Blazers and the concerns regarding the deal. Also, some are worried that the Moda Center's needed renovations could eventually still push the new owners to relocate the team out of Portland. Joining host Claudia Meza on this midweek round-up is executive producer John Notarianni. Discussed in Today's Episode: What to Know About the Portland Trail Blazers' New Owners [OPB] New Blazers Owner Dundon To Tackle Arena Issue [Sports Business Journal] City Cast Portland is hiring a social media manager! If you have experience creating incredible social content, and want to help make your neighbors more engaged and informed, we'd love to hear from you. Applications are due August 22nd — find more information and apply here. Become a member of City Cast Portland today! Get all the details and sign up here. Who would you like to hear on City Cast Portland? Shoot us an email at portland@citycast.fm, or leave us a voicemail at 503-208-5448. Want more Portland news? Then make sure to sign up for our morning newsletter, Hey Portland, and be sure to follow us on Instagram. Looking to advertise on City Cast Portland? Check out our options for podcast and newsletter ads at citycast.fm/advertise. Learn more about the sponsors of this August 20th episode: Montavilla Jazz PaintCare Oregon Health Authority Visit Walla Walla Oregon Coast Visitor Association - Use code 50off for 50% off
Have you ever wondered what it would take to make the shift from an RN to a CRNA? Would it be manageable? Today we're sharing our conversation with two talented women who are in the middle of that process right now. Larry and Kevin sat down with Jasmine Dhalla, BSN, BLS, ACLS, PALS, CCRN, TNCC and Damilola Olarenwaju, BSN, RN, CCRN, TNCC at the AANA Congress in Nashville so they could share their powerful journeys as ICU nurses taking their first steps toward nurse anesthesia school. Here's some of what we discuss in this episode:
No matter how long you've lived in Portland, someone's always been here longer — and swears the city used to be better. But is Portland really “over”? Today we're digging into that question with comedian Jay Flewelling and some of the city's sharpest comics — many of whom you can see live this Friday at Kickstand Comedy in the Park, presented with City Cast Portland! Join us at Kickstand Comedy in the Park, hosted by Julia Corral and Rachelle Cochrane, at Laurelhurst Park this Friday, August 22 at 6:30 p.m.! City Cast Portland is hiring a social media manager! If you have experience creating incredible social content, and want to help make your neighbors more engaged and informed, we'd love to hear from you. Applications are due August 22nd — find more information and apply here. Become a member of City Cast Portland today! Get all the details and sign up here. Who would you like to hear on City Cast Portland? Shoot us an email at portland@citycast.fm, or leave us a voicemail at 503-208-5448. Want more Portland news? Then make sure to sign up for our morning newsletter, Hey Portland, and be sure to follow us on Instagram. Looking to advertise on City Cast Portland? Check out our options for podcast and newsletter ads at citycast.fm/advertise. Learn more about the sponsors of this August 19th episode: Montavilla Jazz PaintCare Oregon Health Authority Visit Walla Walla Oregon Coast Visitor Association - Use code 50off for 50% off
This is part two of the framework; if you missed part one, head to episode 175 and start there so you're all caught up. In this episode of Experiencing Data, I continue my deep dive into the MIRRR UX Framework for designing trustworthy agentic AI applications. Building on Part 1's “Monitor” and “Interrupt,” I unpack the three R's: Redirect, Rerun, and Rollback—and share practical strategies for data product managers and leaders tasked with creating AI systems people will actually trust and use. I explain human-centered approaches to thinking about automation and how to handle unexpected outcomes in agentic AI applications without losing user confidence. I am hoping this control framework will help you get more value out of your data while simultaneously creating value for the human stakeholders, users, and customers. Highlights / Skip to: Introducing the MIRRR UX Framework (1:08) Designing for trust and user adoption plus perspectives you should be including when designing systems. (2:31) Monitor and interrupt controls let humans pause anything from a single AI task to the entire agent (3:17) Explaining “redirection” in the example context of use cases for claims adjusters working on insurance claims—so adjusters (users) can focus on important decisions. (4:35) Rerun controls: lets humans redo an angentic task after unexpected results, preventing errors and building trust in early AI rollouts (11:12) Rerun vs. Redirect: what the difference is in the context of AI, using additional use cases from the insurance claim processing domain (12:07) Empathy and user experience in AI adoption, and how the most useful insights come from directly observing users—not from analytics (18:28) Thinking about agentic AI as glue for existing applications and workflows, or as a worker (27:35) Quotes from Today's Episode The value of AI isn't just about technical capability, it's based in large part on whether the end-users will actually trust and adopt it. If we don't design for trust from the start, even the most advanced AI can fail to deliver value." "In agentic AI, knowing when to automate is just as important as knowing what to automate. Smart product and design decisions mean sometimes holding back on full automation until the people, processes, and culture are ready for it." "Sometimes the most valuable thing you can do is slow down, create checkpoints, and give people a chance to course-correct before the work goes too far in the wrong direction." "Reruns and rollbacks shouldn't be seen as failures, they're essential safety mechanisms that protect both the integrity of the work and the trust of the humans in the loop. They give people the confidence to keep using the system, even when mistakes happen." "You can't measure trust in an AI system by counting logins or tracking clicks. True adoption comes from understanding the people using it, listening to them, observing their workflows, and learning what really builds or breaks their confidence." "You'll never learn the real reasons behind a team's choices by only looking at analytics, you have to actually talk to them and watch them work." "Labels matter, what you call a button or an action can shape how people interpret and trust what will happen when they click it." Quotes from Today's Episode Part 1: The MIRRR UX Framework for Designing Trustworthy Agentic AI Applications
✨ **Grab my Creative Direction template for FREE** ✨Curious what the first stage of my brand design projects looks like? Grab the Figma template (and four bonus audio trainings walking you through how to populate it!) below! I'll send it out September 1, 2025 (or automatically after that date) - are you ready?
Discover why ARM mortgage applications are 25 percent higher. Are you on track for financial freedom...or not? Financial freedom is a combination of money, compounding and time (my McT Formula). How well you invest can make the biggest difference to your financial freedom and lifestyle. If you invested well for the long-term, what a difference it would make because the difference between investing $100k and earning 5 percent or 10 percent on your money over 30 years, is the difference between it growing to $432,194 or $1,744,940, an increase of over $1.3 million dollars. Your compounding rate, and how well you invest, matters! INVESTING IS WHAT THE BE WEALTHY & SMART VIP EXPERIENCE IS ALL ABOUT - Invest in digital assets and stock ETFs for potential high compounding rates - Receive an Asset Allocation model with ticker symbols and what % to invest -Monthly LIVE investment webinars with Linda 10 months per year, with Q & A -Private VIP Facebook group with daily community interaction -Weekly investment commentary -Extra educational wealth classes available -Pay once, have lifetime access! NO recurring fees. -US and foreign investors are welcome -No minimum $ amount to invest -Tech Team available for digital assets (for hire per hour) For a limited time, enjoy a 50% savings on my private investing group, the Be Wealthy & Smart VIP Experience. Pay once and enjoy lifetime access without any recurring fees. Enter "SAVE50" to save 50% here: http://tinyurl.com/InvestingVIP Or set up a complimentary conversation to answer your questions about the Be Wealthy & Smart VIP Experience. Request an appointment to talk with Linda here: https://tinyurl.com/TalkWithLinda (yes, you talk to Linda!). SUBSCRIBE TO BE WEALTHY & SMART Click Here to Subscribe Via iTunes Click Here to Subscribe Via Stitcher on an Android Device Click Here to Subscribe Via RSS Feed LINDA'S WEALTH BOOKS 1. Get my book, "3 Steps to Quantum Wealth: The Wealth Heiress' Guide to Financial Freedom by Investing in Cryptocurrencies". 2. Get my book, “You're Already a Wealth Heiress, Now Think and Act Like One: 6 Practical Steps to Make It a Reality Now!” Men love it too! After all, you are Wealth Heirs. :) International buyers (if you live outside of the US) get my book here. WANT MORE FROM LINDA? Check out her programs. Join her on Instagram. WEALTH LIBRARY OF PODCASTS Listen to the full wealth library of podcasts from the beginning. SPECIAL DEALS #Ad Apply for a Gemini credit card and get FREE XRP back (or any crypto you choose) when you use the card. Charge $3000 in first 90 days and earn $200 in crypto rewards when you use this link to apply and are approved: https://tinyurl.com/geminixrp This is a credit card, NOT a debit card. There are great rewards. Set your choice to EARN FREE XRP! #Ad Protect yourself online with a Virtual Private Network (VPN). Get 3 MONTHS FREE when you sign up for a NORD VPN plan here. #Ad To safely and securely store crypto, I recommend using a Tangem wallet. Get a 10% discount when you purchase here. #Ad If you are looking to simplify your crypto tax reporting, use Koinly. It is highly recommended and so easy for tax reporting. You can save $20, click here. Be Wealthy & Smart,™ is a personal finance show with self-made millionaire Linda P. Jones, America's Wealth Mentor.™ Learn simple steps that make a big difference to your financial freedom. (This post contains affiliate links. If you click on a link and make a purchase, I may receive a commission. There is no additional cost to you.)
A gentile woman came to ask Jesus for healing, but He was silent, at first. What can we learn from this powerful interaction in regards to our prayer life? Find out as Chris Barras shares.To watch the full message go to https://youtu.be/kZevX0hk09EShare your stories, prayer requests, or your response to this devotional in the comments below.If you would like to know more about New Life, who we are, what we believe, or when we meet, visit http://newlife.church. Or you can fill out a digital connection card at http://newlife.church/connect - we would love to get to know you better!
Peter Kennard is one of the most uncompromising, clear eyed political artists of our time, a pioneer of photomontage. His work rips through the surface of state power, war, capitalism and environmental destruction, and lays bare what those systems try to obscure - the human cost. Peter has created fiercely political images that have travelled far beyond the gallery wall, into newspapers, onto placards, pasted on street corners and burned into the minds of generations. His work for the Campaign for Nuclear Disarmament, the stop the war coalition and his unflinching responses to Gaza and Ukraine are just a few examples. Peter and Ceri discuss the people and moments that shaped him, how he´s sustained prolific output without losing his fire, and why getting the work out into the world has always been just as important as making it. KEY TAKEAWAYS For over 50 years, Peter has used photo montage to speak truth to power, fusing activism with artistry. Peter doesn´t make work about politics, he makes it for political change. It is important to make art that communicates directly and inspires social change, despite the challenges of a corporate art world. BEST MOMENTS “Peter doesn't just make art. He dissects the very machinery of war, power and propaganda - one torn photograph at a time.” “It's not about being liked, it's about making work that matters, work that outlives trends. Speaks across generations and refuses to look away.” EPISODE RESOURCES https://www.peterkennard.com PODCAST HOST BIO With over 35 years in the art world, Ceri has worked closely with leading artists and arts professionals, managed public and private galleries and charities, and curated more than 250 exhibitions and events. She sold artworks to major museums and private collectors and commissioned thousands of works across diverse media, from renowned artists such as John Akomfrah, Pipilotti Rist, Rafael Lozano-Hemmer and Vito Acconci. Now, she wants to share her extensive knowledge with you, so you can excel and achieve your goals. **** The Artist Mastermind Circle: Ready to stop second-guessing and start building momentum in your art career? Applications are now open for the next Artist Mastermind Circle—a six-month coaching programme for mid-career artists who are serious about growing their confidence, income, and opportunities. Apply by September 15th 2025 at https://cerihand.com/artist-mastermind-circle/ and take the next bold step. Ceri Hand Coaching Membership: Group coaching, live art surgeries, exclusive masterclasses, portfolio reviews, weekly challenges. Access our library of content and resource hub anytime and enjoy special discounts within a vibrant community of peers and professionals. Ready to transform your art career? Join today! https://cerihand.com/membership/ **** Unlock Your Artworld Network Self Study Course Our self-study video course, "Unlock Your Artworld Network," offers a straightforward 5-step framework to help you build valuable relationships effortlessly. Gain the tools and confidence you need to create new opportunities and thrive in the art world today. https://cerihand.com/courses/unlock_your_artworld_network/ **** Book a Discovery Call Today To schedule a personalised 1-2-1 coaching session with Ceri or explore our group coaching options, simply email us at hello@cerihand.com **** Discover Your Extraordinary Creativity Visit www.cerihand.com to learn how we can help you become an extraordinary creative. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: cancer reserach may lead to T1D treatment, GLP-1 oral pill moves forward, Tandem pharmacy moves, Medtronic-Abbott sensor unveield, parents of kids with T1D see income drop, Mannkind submits Afrezza for pediatrics, diabetes scholarships and more! Find out more about Moms' Night Out Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX Cornell researchers have developed an implant system that can treat type 1 diabetes by supplying extra oxygen to densely packed insulin-secreting cells, without the need for immunosuppression. The system could also potentially provide long-term treatment for a range of chronic diseases. This lab has produced previous implantable devices that have proved effective in controlling blood sugar in diabetic mice, but they can only last so long. "It's the proof of concept. We really proved that oxygenation is important, and oxygenation will support high cell-density capsules," Tempelman said. "The capsules are immune protective and last for a long time without having some kind of fouling of the membrane. The body never likes it when you put a foreign substance in. So that's the engineering in the Ma Lab, to look for materials and coatings for the materials that are immune protective, but also don't invoke excess response from the body because of the material." The next step will be to implant the system in a pig model, and also test it with human stem cells. The researchers are interested in eventually trying to use the system for implanting different cell types in humans for long-term treatment of chronic diseases, according to Tempelman, who is CEO of Persista Bio Inc., a new startup she founded with Ma and Flanders that is licensing these technologies. https://medicalxpress.com/news/2025-08-implant-diabetes-oxygenating-insulin-cells.html XX Mayo Clinic cancer research may be big news for T1D. After identifying a sugar molecule that cancer cells use on their surfaces to hide from the immune system, the researchers have found the same molecule may eventually help in the treatment of type 1. Cancer cells use a variety of methods to evade immune response, including coating themselves in a sugar molecule known as sialic acid. The researchers found in a preclinical model of type 1 diabetes that it's possible to dress up beta cells with the same sugar molecule, enabling the immune system to tolerate the cells. The findings show that it's possible to engineer beta cells that do not prompt an immune response In the preclinical models, the team found that the engineered cells were 90% effective in preventing the development of type 1 diabetes. The beta cells that are typically destroyed by the immune system in type 1 diabetes were preserved. https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-researchers-find-sugar-coating-cells-can-protect-those-typically-destroyed-in-type-1-diabetes/ XX A daily pill may be as effective in lowering blood sugar and aiding weight loss in people with Type 2 diabetes as the popular injectable drugs Mounjaro and Ozempic, according to results of a clinical trial announced by Eli Lilly on Thursday morning. The drug, orforglipron, is a GLP-1, a class of drugs that have become blockbusters because of their weight-loss effects. But the GLP-1s on the market now are expensive, must be kept refrigerated and must be injected. A pill that produces similar results has the potential to become far more widely used, though it is also expected to be expensive. Lilly said it would seek approval from the Food and Drug Administration later this year to market orforglipron for obesity and early in 2026 for diabetes. https://www.nytimes.com/2025/04/17/health/pill-glp-1-eli-lilly.html XX Use of diabetes technology has dramatically increased and glycemic control has improved among people with type 1 diabetes (T1D) in the US over the past 15 years, but at the same time, overall achievement of an A1c level < 7% remains low and socioeconomic and racial disparities have widened. These findings came from an analysis of national electronic health records of nearly 200,000 children and adults with T1D by Michael Fang, PhD, of the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, and colleagues. The study was published online on August 11, 2025, in JAMA Network Open. Use of continuous glucose monitors (CGMs) increased substantially from 2009-2011 to 2021-2023, from less than 5% in both children and adults to more than 80% and over half, respectively. While A1c levels did drop over the 15 years, just 1 in 5 children and slightly over a quarter of adults achieved a level < 7%. The average A1c level stayed above 8%, with ethnic minorities and low-income patients seeing the smallest gains. https://www.medscape.com/viewarticle/diabetes-tech-use-rise-a1c-reductions-still-lag-2025a1000lc9 XX Inflammation may predict how well people with diabetes respond to depression treatment, and the effects differ dramatically between type 1 and type 2 diabetes. Diabetes and depression often appear together. Indeed, depression is more than three times more prevalent in people with type 1 diabetes (T1D) and nearly twice as prevalent in people with type 2 diabetes (T2D). When they appear together, treatment for depression can vary widely. In a new study, researchers from the German Diabetes Center (DDZ), the Research Institute of the Diabetes Academy Mergentheim (FIDAM), and the German Center for Diabetes Research (DZD) investigated how inflammation in the body relates to improvement in depression symptoms in people with T1D and T2D. The researchers combined data from three previous German randomized clinical trials that aimed to reduce elevated depressive symptoms and diabetes distress in people with type 1 or type 2 diabetes. Diabetes distress is characterized by feelings of overwhelm, frustration, guilt and worry about diabetes management and its potential complications. A total of 332 participants with T1D and 189 with T2D who had completed both a baseline and 12-month follow-up examination were included in the present study. Measures included depression using the Center for Epidemiological Studies Depression scale (CES-D), blood tests for 76 inflammatory biomarkers, and symptoms broken down into cognitive-affective (e.g., feeling hopeless), somatic (e.g., poor sleep, fatigue), and anhedonia (loss of pleasure) clusters. After adjusting for factors like age, body mass index (BMI), diabetes duration, cholesterol, and co-existing illnesses, the researchers found that in patients with T1D, higher baseline inflammation was linked to smaller improvements in depression. Inflammation seemed to be more connected to physical/somatic symptoms in T1D patients. In those with T2D, higher baseline inflammation was linked to greater improvements in depression. For these patients, the effect was strongest for cognitive-affective and anhedonia – so, emotional and motivational – symptoms. The researchers weren't sure what caused the difference between T1D and T2D, but they suggest it might be due to the different forms of immune activation seen in each condition. That is, autoimmune processes in type 1 and metabolic inflammation in type 2. https://newatlas.com/health-wellbeing/inflammation-diabetes-depression-treatment/ XX Parents of children diagnosed with type 1 diabetes suffer an income drop in the years following the diagnosis. The impact is more pronounced in mothers, especially mothers of children diagnosed in preschool years. And these findings come from a European study.. not the US. Previous research has shown that parents of children with type 1 diabetes are at increased risk of stress-related symptoms and may need to reduce their working hours. "In our study, we observed reduced parental work-related incomes in the years following the child's type 1 diabetes diagnosis. The drop was larger in mothers than in fathers. Since mothers earned significantly less than fathers in absolute terms, even before the child fell ill, the relative drop in mothers was 6.6% the year following diagnosis compared to 1.5% in fathers. We further note the greatest impact on work-related incomes in mothers of children diagnosed at preschool age," says Beatrice Kennedy, physician at the Endocrine and Diabetes unit at Uppsala University Hospital and Associate Professor of Medical Epidemiology at Uppsala University, who led the study. This is a huge study, builds on data from national population and health registers and the Swedish Child Diabetes Register (Swediabkids). The study includes the parents of more than 13,000 children diagnosed with type 1 diabetes in Sweden in 1993−2014, as well as more than half a million parents in the general population who have children not diagnosed with diabetes. The researchers observed that the maternal pension-qualifying incomes (a composite outcome including work-related income and societal benefits) initially increased after the child's diagnosis. This was attributable to mothers applying for the parental care allowance from the Swedish Social Insurance Agency. The parental care allowance was intended to compensate for disease-related loss of work-related income and contribute toward disease-specific costs. When the research team investigated long-term effects in mothers, they found that the pension-qualifying incomes gradually decreased after eight years, and had not recovered by the end of follow-up − 17 years after the children were diagnosed. https://www.news-medical.net/news/20250811/Mothers-face-greater-financial-impact-following-childe28099s-type-1-diabetes-diagnosis.aspx XX The U.S. Department of Justice has reached a settlement with Metro Nashville Public Schools after allegations that the district violated the Americans with Disabilities Act. The parents of a student at the Ross Early Learning Center requested that the school monitor their child's glucose monitor. Investigators found the school refused to do so, despite the child's Type 1 Diabetes diagnosis. As part of the settlement, MNPS agreed to change its policies to allow the use of these devices, ensure trained staff can monitor them throughout the entire school day and at school activities, and improve communication with parents. https://www.wsmv.com/2025/08/12/metro-nashville-public-schools-settles-allegations-it-discriminated-against-students-with-diabetes/ XX Modular Medical has unveiled Pivot, its next-generation insulin patch pump technology aimed at simplifying diabetes care. The company announced its new pump for “almost-pumpers” at the Association of Diabetes Care & Education Specialists (“ADCES”) Conference in Phoenix, Arizona this weekend. It aims for Pivot to target adults with a user-friendly, affordable design. Modular Medical's current pump, the MODD1, won FDA clearance nearly a year ago. It features new microfluidics technology to allow for the low-cost pumping of insulin. The system has a reservoir size of 300 units/3mL. Users can monitor the pump activity with their cell phone and do not require an external controller. The pump uses a provided, single-use, disposable battery. The company announced recently that it validated its insulin pump cartridge line for human-use production in the U.S. Days later, it reported the first human use of the MODD1 pump. Now, it has taken the next steps with the debut of a next-gen pump, set for FDA submission in October. Modular Medical also gamifies diabetes care The company also said ADCES is the place where it will showcase the first playable level of its new Pivot pump gamified trainin module. Level Ex, a developer of medical games, develops the module. Modular Medical said gamification offers a way to make medical training more effective and efficient while improving information retention. Given the complexity in pump uptake, the company hopes to provide an easy way to bring its technology to clinicians and patients. The company expects to have training modules available at the same time as the pump's planned launch in 2026. “Level One is free because diabetes mastery shouldn't come with a price tag,” Sam Glassenberg, CEO of Level Ex, said. “Modular Medical is breaking barriers too – bringing pump therapy to more people through smart, accessible design. Together, we intend to make diabetes management simpler and more inclusive. “People learn best through play – and we believe they want to learn about insulin pumps the same way. In Level One, players aren't just mastering diabetes management through gameplay – they're asking to ‘play' with pumps: to explore how they work, understand their benefits, and build confidence before using them in real life. Our partnership with Modular Medical helps make that possible.” https://www.drugdeliverybusiness.com/modular-medical-unveils-next-gen-insulin-pump/ XX On Tuesday, 12 August 2025, Tandem Diabetes Care (NASDAQ:TNDM) presented at the Canaccord Genuity's 45th Annual Growth Conference, outlining strategic shifts and market focus. The company highlighted its plans for commercial transformation in the U.S. and expansion in international markets, alongside addressing competitive challenges and regulatory impacts. While optimistic about growth in Outside the U.S. (OUS) markets, Tandem is navigating a more competitive landscape domestically. We have entered into the pharmacy channel with Mobi only. And so as Mobi's been building up volume, we're getting experience and we're really learning and understanding what pharmacy offers to us. And the proof points have proved out the thesis I said earlier, which is it can really reduce that barrier for patients, is the out of pocket cost. And so we've decided to accelerate our strategy and where we were starting just with Mobi, we are now moving t slim supplies into the pharmacy channel, and that will kick into gear in the fourth quarter. So as people are looking at the cadence of sales for the remainder of the year with this reframing, many folks are seeing what looks like a a might be an outsized fourth quarter and and having trouble understanding those dynamics. We'll be adding the tSIM supplies to those contracts. We also have more coverage. We will have it in the coming weeks effective this year, so we will be increasing that 30% rate before the end of the year. And then, obviously, everyone's in the same cycle right now already negotiating and discussing their 2026 coverage. And so 30% is the floor. We do expect to continue to grow that coverage in the coming years, and ultimately have a much broader access. Absolutely. It's an exciting technology that allows for us to have an infusion set that extends the wear time from three days to up to seven days. So we're able to use that as part of an independent infusion set, which would then be used with the t slim and with the mobi pump today. But we're also using that same technology as part of the site that's used for mobi when you use it with a tubeless cartridge. So next year, we will launch Mobi in a patch configuration. It uses the same pump that's available today, but by using a modified cartridge, you're able to wear it as a patch pump. So one of the things we announced on the call is that we're using this extended wear technology as part of that site. So what it allows you to do is to change the portion that you wear in your skin separate from the timing of when you change the insulin cartridge. So it allows for that extended wear time, reduction of burden to the patient, which is especially important for higher volume insulin users as we expand into type two. So from here, we will launch the extended wear site next year along with we'll do a separate regulatory filing for the cartridge portion for Mobi that includes this extended wear technology as a predicate device. So that's another filing that we'll need to do, but we have the clearance today for the independent infusion set, but we'll file another five ten k for use of the extended wear technology as part of the tubeless Mobi feature. https://za.investing.com/news/transcripts/tandem-diabetes-at-canaccord-conference-strategic-shifts-and-market-focus-93CH-3834464 XX MannKind today announced a significant regulatory submission and a large financing agreement with Blackstone. The company submitted its lead inhaled insulin product for expanded FDA approval and secured $500 million in funding, it said. First, the Danbury, Connecticut-based company announced that it submitted a supplemental Biologics License Application (sBLA) for Afrezza, its inhaled insulin product, in the pediatric population. MannKind Director of Medical and Scientific Engagement Joanne Rinker, MS, RDN, BC-ADM, CDCES, LDN, FADCES, told Drug Delivery Business News at ADA 2025 that a submission was on the way for children and adolescents aged 4-17 years old. Further data shared at ADA found Afrezza both safe and effective in that age range. Afrezza is a fast-acting insulin formulation delivered through an inhaler device. MannKind engineered the mechanical inhaler device to slowly bring powder into the lung. A small compartment opens for the insertion of the insulin cartridge, then the user closes it. The only other component is a mouthpiece for the sake of cleanliness. Then, the inhalation takes just two seconds. It requires no electronics or extra components. The company expects a review acceptance decision early in the fourth quarter of 2025. “The submission of our supplemental Biologics License Application (sBLA) for Afrezza in pediatric patients is a meaningful milestone for MannKind and people living with diabetes,” said Michael Castagna, CEO of MannKind Corporation. Additional funding provides a significant boost for MannKind MannKind also announced a strategic financing agreement with funds managed by Blackstone worth up to $500 million. The financing provides MannKind with non-dilutive capital to advance its short- and long-term growth strategies. This senior secured credit facility includes a $75 million initial term loan funded at closing. It then has a $125 million delayed draw term loan available for the next 24 months. Finally, it features an additional $300 million uncommitted delayed draw term loan available at the mutual consent of MannKind and Blackstone. The facility bears interest at a calculated SOFR variable rate plus 4.75% and matures in August 2030. “This strategic financing significantly increases our operating flexibility and provides us substantial access to non-dilutive capital on favorable terms, complementing our strong cash position,” said Castagna. “The funding will support the expansion of our commercial team in preparation for the anticipated launch of the pediatric indication for Afrezza, if approved, continued pipeline advancement, potential business development opportunities, and general corporate purposes. Partnering with the Blackstone team on this transaction positions us to accelerate our next phase of growth and innovation.” https://www.drugdeliverybusiness.com/mannkind-fda-submission-pediatrics-500m-blackstone/ XX Medtronic MiniMed Abbott Instinct Sensor [Image from Medtronic Diabetes on LinkedIn] The Medtronic Diabetes business today took to social media to share an early preview of a new integrated Abbott sensor for its insulin delivery systems. Medtronic Diabetes — soon to be MiniMed after its planned separation from the medtech giant – said in the post that the new sensor specifically designed for its own systems is called “Instinct.” “Get a sneak peek at what's coming next: the Instinct sensor,” the business unit's account wrote. “Made by Abbott, the Instinct sensor is designed exclusively for MiniMed systems. We'll share more details about the Instinct sensor when it's commercially available.” The sensor, built on the Abbott FreeStyle Libre platform, reflects “the power of the partnership,” Abbott EVP, Diabetes Care, Chris Scoggins, told Drug Delivery Business News earlier this year. Medtronic and Abbott — two of the largest diabetes tech companies in the world — announced a year ago that they entered into a global partnership pairing Abbott continuous glucose monitors (CGMs) with Medtronic insulin delivery systems. The partnership aims to collaborate on a system based on Abbott's FreeStyle Libre CGMs with Medtronic's automated insulin delivery technology (the latest generation being the MiniMed 780G) and smart insulin pen systems, such as the InPen system. Read more about Medtronic, Abbott and the rest of the diabetes tech industry in our free Diabetes Technology Special Report. Medtronic's systems previously used its own CGMs, such as the Guardian 4 and the Simplera platform, and the company intends to continue using those systems as part of a comprehensive CGM portfolio. Under the companies' agreement, the systems would be sold exclusively by Medtronic — including the Abbott CGM. The companies brought the partnership a step further in April when Medtronic announced the submission of an interoperable pump with the Abbott sensor technology to the FDA. They plan to share more details following the expected FDA clearance, which remains pending. Management also recently emphasized the multi-year nature of the partnership, meaning Medtronic could pair current and future pumps with other Abbott sensors in the future. That could hint at integration with the company's future dual glucose-ketone monitor, as a number of pump makers have already announced collaborations to pair their systems with the sensor once it hits the market. https://www.drugdeliverybusiness.com/medtronic-diabetes-previews-abbott-sensor-minimed/ XX Governor Glenn Youngkin joined Civica officials at the company's Petersburg manufacturing facility to announce a $3 million grant from the Commonwealth of Virginia to accelerate Civica's efforts to develop and produce affordable insulin for Americans living with diabetes. CivicaRx Logo "We are proud to partner with Civica in their mission to make essential medicines more accessible," said Governor Youngkin. "This investment reflects our belief in the power of public-private collaboration to improve lives and strengthen communities." These funds will support the production of insulin aspart, a rapid-acting human insulin analog used to regulate blood sugar in adults and children with diabetes. Civica plans to produce both rapid- and long-acting insulins at its state-of-the-art manufacturing facility in Petersburg, Va., where the company now employs more than 200 skilled workers.1 Over 8 million people living with diabetes need rapid-acting and/or long-acting insulin. The Governor also announced that he had officially proclaimed August 7 – 14 2025 'Life Sciences Week' demonstrating the Commonwealth's commitment to "accelerating the advancement of the life sciences through public-private partnerships, STEM education, workforce development, and sustained investment in research and development." "We are grateful for the Commonwealth's support," said Ned McCoy, Civica's President and CEO. "This funding will help us move closer toward our goal of ensuring that no one has to choose between insulin and other basic needs." Civica and Virginia officials were joined by Lynn Starr, Chief Global Advocacy Officer of Breakthrough T1D, the leading global type 1 diabetes research and advocacy organization. "More than one million American adults live with type 1 diabetes, and many still, sadly, ration their insulin, due to the prohibitively high cost of this necessary medication," said Starr. "Civica's work will help to make insulin more affordable for people across the country." Breakthrough T1D is among more than two dozen organizations and philanthropists, along with the states of Virginia and California, that have partnered with Civica to support the development of affordable insulins. Civica's insulin initiative aims to provide patients with predictable, transparent pricing — no more than $30 per vial or $55 for a box of five pens — regardless of insurance status. About Civica Civica is a nonprofit pharmaceutical company established to address drug shortages. It was founded by a group of U.S. health systems and philanthropies who, after more than a decade of chronic shortages, recognized that the market was not self-correcting and that a different approach is required. Civica works to deliver a safe, stable, and affordable supply of essential medicines to U.S. patients. Media Contact: Liz Power liz.power@civicarx.org +1 860 501 3849 https://cbs4indy.com/business/press-releases/cision/20250807NY46213/governor-glenn-youngkin-announces-3-million-grant-to-support-civicas-affordable-insulin-programs/ XX If you or someone you love is living with diabetes, you already know the fight isn't just medical—it's financial, too. Between daily supplies, doctor visits, and long-term care, the cost of managing type 1 or type 2 diabetes can be overwhelming. Add college or trade school into the equation, and suddenly staying healthy competes with building a future. That's where scholarships for students with diabetes—like Beyond Scholars and others listed here—step in. Whether you're headed to a university, a two-year college, or a hands-on trade program, these opportunities were created to ease the load. Scholarships for students with diabetes Beyond Scholars (from Beyond Type 1): $10,000 for recently graduated high school seniors with type 1 diabetes or type 2 diabetes entering college or trade school. This is one of the largest needs-based diabetes scholarships in the United States. This year, awardees will also receive 6 months of wellness coaching through Risely Health. Applications open: July 25, 2025 Deadline: August 29, 2025 Winners announced: October 2025 https://beyondtype1.org/beyond-scholars-diabetes-scholarships-college-trade-school/ XX Nick Jonas and Kyle Rudolph are using their platforms for a good cause. On Tuesday, Aug. 12, the singer and the former NFL tight end (via his professional fundraising platform Alltroo) announced they're teaming up to launch a rally featuring a fan-coveted prize: a custom 2025 Volkswagen ID. Buzz electric bus that the Jonas Brothers have brought along for their 20th anniversary tour. “Ten years ago, we hit the road with a goal to change what it means to live with diabetes. Since then, Beyond Type 1 has grown into the world's largest digital diabetes community, offering the tools, education, and peer support needed to not only survive but thrive with diabetes,” Jonas, who co-founded Beyond Type 1 (a nonprofit that advocates for those living with diabetes), says in a statement. “We've challenged stigma, built community, provided life-saving resources, and collectively driven global innovation toward prevention and cure. This milestone is a moment to rally even more support for our mission, and partnering with Alltroo helps us do that in a powerful, engaging way.” Related Stories Nick Jonas on Managing His Diabetes: 'The Mental and Emotional Health Aspect Is Really Important' nick jonas Nick Jonas Says He Was Diagnosed with Diabetes After Joe Told Their Parents: 'Something's Really Wrong' Joe Jonas and Nick Jonas attend the amfAR Cannes Gala 30th edition at Hotel du Cap-Eden-Roc on May 23, 2024 For Rudolph, the campaign is about "celebrating Beyond Type 1's incredible work over the past decade, and standing behind their vision of a world where everyone with diabetes — or at risk of it — has access to the knowledge, care and support needed for early diagnosis and lifelong health." While the rally is live on Alltroo.com, fans can also scan QR codes available at all 36 Jonas Brothers concert stops to enter for a chance to win the electric bus. (A winner will be selected on November 14, which is World Diabetes Day.) Jonas, 32, has long been open about his Type 1 diabetes diagnosis at 13 years old. "I had this kind of wrench thrown into things when I was diagnosed and it took a while to figure out how to count carbs to properly dose for insulin and what things would affect me in different ways," he previously told PEOPLE. "When I was first diagnosed, I was sitting in the hospital and was scared to death, honestly, while I was learning about how to manage this new thing I was dealing with," Jonas recalled. "It would have been amazing to have someone to look at at that time to say, oh, this is a person living with it and they're following their dreams. They're doing what they want to do with their lives and not letting it slow them down." https://people.com/nick-jonas-kyle-rudolph-launch-fan-rally-diabetes-awareness-11788684
The 25th amendment. A few years before JFK was shot, an idealistic young lawyer set out on a mission to convince people something essential was missing from the Constitution: clear instructions for what should happen if a U.S. president was no longer able to serve. On this episode of our ongoing series We the People, the story behind one of the last amendments to the Constitution, and the man who got it done. This story originally published in March 2025.Guest:John Feerick, Norris Professor of Law at Fordham Law School and author of The Twenty-Fifth Amendment - Its Complete History and Applications.To access bonus episodes and listen to Throughline sponsor-free, subscribe to Throughline+ via Apple Podcasts or at plus.npr.org/throughline.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
Dave speaks with Erann Lincoln, an alum of the Coaching for Leaders Academy, on how she started small to build stronger relationships with her team. Applications to the Coaching for Leaders Academy will open the first week of September. Visit the Academy page to request an early invitation.
Artificial intelligence has been a frequent topic on Sinica in recent years — but usually through the lens of the two countries that have produced the leading models and companies: the United States and China. We've covered generative AI, national strategies, governance frameworks, and the geopolitical implications of AI leadership.This webinar, broadcast on the morning of August 14, broadens that lens to explore how other countries — and especially Ukraine — are approaching AI in the public sector. Around the world, governments are experimenting with AI well beyond chatbots and text generation: China's “City Brain” optimizes traffic, energy use, and public safety; U.S. agencies are streamlining services and automating benefits processing; and elsewhere, smart grids, predictive infrastructure planning, and AI-enabled e-governance are reshaping public administration. These projects reveal both the promise and the complexity of bringing AI into government — along with valid concerns over privacy, fairness, and inclusiveness.We'll look at what lessons Ukraine might draw from U.S. and Chinese experiences, the opportunities and challenges of adapting these practices, and the strategic risks of sourcing AI solutions from different providers — especially in the context of Ukraine's eventual postwar reconstruction.Joining us are three distinguished guests:Dmytro Yefremov, Board Member of the Ukrainian Association of Sinologists, with deep expertise in China's political and technological strategies and Ukraine's policy landscape.Wang Guan, Chairman of Learnable.ai in China, bringing extensive experience in AI applications for public administration and education.Karman Lucero, Associate Research Scholar and Senior Fellow at Yale Law School's Paul Tsai China Center, whose work focuses on Chinese law, governance, and the regulation of emerging technologies.Thanks to the Ukrainian Platform for Contemporary China, the Ukrainian Association of Sinologists, and the Center for Slavic, Eurasian, and East European Studies at the University of North Carolina–Chapel Hill for organizing and sponsoring today's event. Special thanks to Vita Golod for putting together the panel and inviting me to moderate.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Have you ever made a regrettable decision in the moment that you would have made differently if you had given yourself a bit more time and space to reason it through? I think we have all been there. Many are there right now! Every time we decide something in the present based on desperation, impatience, or fear, the future version of ourselves and other, suffer for it. There have been countless examples of owners deciding on hiring, programs, expansion, menu items etc that seemed like a good idea, until the more reasonable future Today on Shift Break we will be talking about the importance of considering the the downstream impacts of the bright ideas and brain waves we get so present you won't inadvertently sabotage future you's success. Here are some related episodes to explore: 184 : Making Great Business Decisions w/ Dave Stachowiak 253 : Mindsets that Sabotage Success 414: Secret Ingredients for a Successful Coffee Shop KEY HOLDER COACHING GROUPS ARE LIVE! Are you a coffee shop owner looking to join a community of other owners to help bring perspective, insight, encouragement, and accountability in a well curated setting? Then you need to apply to join Key holder Coaching Groups! Applications are now open for fall 2025 Cohort: Click below to learn more: APPLY TO KEY HOLDER COACHING GROUPS HIRE KTTS CONSULTING AND COACHING! If you are a cafe owner and want to work one on one with me to bring your shop to its next level and help bring you joy and freedom in the process then email chris@keystothshop.com of book a free call now: https://calendly.com/chrisdeferio/30min Thank you to out sponsors! Everything you need for back of the house operations https://rattleware.qualitybystainless.com/ The best and most revered espresso machines on the planet: www.lamarzoccousa.com
In this episode, we explore evidence-based pharmacotherapy for bulimia nervosa, including why higher doses of SSRIs work better than standard dosing, which medications to avoid completely, and how antidepressants can be effective even without depression being present. Why does fluoxetine require 60 mg daily for optimal results? Faculty: Scott Crow M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 0.75 CME: Pharmacotherapy of Eating Disorders: An Update Bulimia Nervosa: Medications That Work
Published August 14, 2025 In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, discuss recent news about the use of artificial intelligence (AI) tools in healthcare. Together, they explore:Applications of AI tools in clinical diagnostics to identify dementia, cardiovascular conditions, and parasites.Ethical considerations, including global disparities in access to AI tools and environmental impacts.ResourcesUse of artificial intelligence and digital slide scanning for detection of intestinal protozoa in trichrome-stained stool specimensMayo Clinic's AI tool identifies 9 dementia types, including Alzheimer's, with one scanAI computing power is splitting the world into haves and have-nots - The New York Times
Ever find yourself hustling hard, checking all the right boxes, and still feeling unfulfilled? Sarah Harris's life seemed picture-perfect on paper: two advanced degrees, a family, and a high-paying 9-to-5 – but ditching alcohol in her 30's cracked her wide open to the truth that alignment was missing. In this episode, Sarah shares the story of her spiritual awakening and her journey to becoming an NLP practitioner, human design expert, alcohol-free empowerment coach, and success coach, helping women unlock their authentic blueprint, align with their higher purpose, and create a life that feels fulfilled AF. We dive into why 30% of the population is actually NOT built for the traditional 9-to-5, the myths we've been fed about hard work, and how to work with your energy instead of grinding against it. It is such a juicy conversation. Sarah is also an alum of the Empowered AF 5X Coach Certification Program and her transformation is proof of what's possible. Want to be next? Applications are open NOW for our fall cohort. IN THIS EPISODE: The hard truth about hustle culture, and how misalignment with your true energy type could be draining your soul (and your spark!) How Sarah's decision to ditch alcohol at 39 didn't just supercharge her intuition - it was the domino that toppled her entire “picture perfect” life and ignited her purpose The five Human Design types demystified: what each type really means for your work, energy, and your pathway to deep fulfillment Why “hard work = more abundance” is deeply outdated, and how to break free from beliefs that keep you stuck in someone else's dream LINKS/RESOURCES MENTIONED Follow Sarah on Instagram and visit her website, where you'll find a weekly newsletter and all kinds of fun freebies. If you know you're meant to help other people change their relationship with alcohol and achieve deep healing (along with their bigger dreams), apply for the Empowered AF 5X Coach Certification Program – and get 5x certified as a world class alcohol-free coach. Applications are now open. Awarded the most empowering book in the sober curious genre, be sure to get your copy of Euphoric: Ditch Alcohol and Gain a Happier, More Confident You today and leave your review. Follow @euphoric.af on Instagram. And as always, rate, review, and subscribe so we can continue spreading our message far and wide.
In this episode of the To Birth and Beyond podcast, Jessie discusses why her signature online program, “To Pregnancy and Beyond” is getting a rebrand after 10 years on the market! Bodies are complex. Life is complex. If you are a woman who wants evidence-based strength training with pelvic floor focus, delivered by a coach who has seen the things, who understands the unique challenges of your physiology - this episode (and program) is for you.- - - - - - - - -If you liked this episode of To Birth and Beyond, tell your friends! Find us on iTunes and Spotify to rate/review/subscribe to the show.Want more? Visit www.ToBirthAndBeyond.com, join our Facebook group (To Birth and Beyond Podcast), and follow us on Instagram @tobirthandbeyondpodcast! Thanks for listening and joining the conversation!Resources and References programs.jessiemundell.com/strong-supportedShow Notes 0:55 - Jessie welcomes us back to another episode!1:44 - Jessie's program, “To Pregnancy and Beyond,” is getting a new name!2:20 - Why this rebrand was necessary!7:18 - BIG program rename reveal!9:06 - Jessie dives into what is changing about the program10:03 - Who this program serves11:45 - Applications are open TODAY - and for a limited time (and some program logistics)14:03 - Special pricing for our Canadian friends - and time-sensitive bonuses15:32 - Jessie shares why she is so excited to get started with you17:21 - Jessie brings the episode to a close
What if you could build a custom AI-powered business tool in minutes without writing a single line of code?It sounds impossible, right? But in this episode, we break down a game-changing process that lets you tap into over 100 ready-made AI agents, customize them for your needs, and deploy them, fast. No coding degree. No tech headaches. No budget blowout.AI educator and founder of Unwind AI, Shubham Saboo, joins Isar Meitis to talk about advanced AI agents, GitHub repositories, and the tools that can transform you from idea to live product in under 30 minutes. Whether you want to boost efficiency, create a client-facing tool, or launch your next million-dollar startup, this conversation hands you the exact blueprint.In this session, you'll discover:How to access and use 100+ open-source AI agents.. no coding required.The easiest way to turn “scary” tech terms like GitHub repos and Python into business-friendly tools.How to make AI apps beautiful and user-friendly with no-code front-end builders.A step-by-step process to create custom agents from scratch using AI models like Gemini.How to deploy your AI tool instantly so it's live for your team or customers.About Leveraging AI The Ultimate AI Course for Business People: https://multiplai.ai/ai-course/ YouTube Full Episodes: https://www.youtube.com/@Multiplai_AI/ Connect with Isar Meitis: https://www.linkedin.com/in/isarmeitis/ Join our Live Sessions, AI Hangouts and newsletter: https://services.multiplai.ai/events If you've enjoyed or benefited from some of the insights of this episode, leave us a five-star review on your favorite podcast platform, and let us know what you learned, found helpful, or liked most about this show!