The Lancet

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Gavin Cleaver, web editor of The Lancet, and the journal’s authors explore their research and its impact on people’s health, health care, and health policy in this regular podcast.

The Lancet


    • May 31, 2025 LATEST EPISODE
    • monthly NEW EPISODES
    • 13m AVG DURATION
    • 661 EPISODES


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    Latest episodes from The Lancet

    Presented at ASCO: the first RCT of CAR T-cell therapy in solid tumours

    Play Episode Listen Later May 31, 2025 14:45


    Changsong Qi joins Chloe Wilson and Ben Abbott of The Lancet to discuss their recently published phase 2 randomised controlled trial investigating Claudin-18 isoform 2-specific CAR T-cell therapy for previously treated advanced gastric or gastro-oesophageal junction cancer.Read the full article:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00860-8/fulltext?dgcid=buzzsprout_icw_podcast_May_25_lancetContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Previewing ASCO 2025

    Play Episode Listen Later May 30, 2025 4:54


    Vania Wisdom, Senior Executive Editor at The Lancet and the journal's Oncology Ambassador, joins Gavin Cleaver to discuss what's being published at this year's American Society of Clinical Oncology (ASCO) meeting, what she's excited to see at the conference, and why ASCO is so important to the field.Continue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Francis Couturaud on treatment of venous thromboembolism

    Play Episode Listen Later Mar 14, 2025 28:30


    Francis Couturaud joins Chloe Wilson of The Lancet to discuss the RENOVE trial, which looks at assessing the efficacy and safety of reduced-dose versus full-dose direct oral anticoagulants in patients in whom extended anticoagulation has been indicated.Read the full paper: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02842-3/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Shawn St Peter on appendicectomy versus antibiotics for acute uncomplicated appendicitis in children

    Play Episode Listen Later Jan 27, 2025 16:01


    This week, we discuss treatment approaches for uncomplicated appendicitis in children following the publication of a trial in our January 18th issue. Lead author Shawn St Peter, general paediatric surgeon and surgeon-in-chief at Children's Mercy Hospital, Kansas City, spoke with Callam Davidson about the motivation behind the study, key findings, and what the results mean for clinical practice.Read the full article:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02420-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Michael Heneka on passive anti-amyloid β immunotherapy in Alzheimer's disease

    Play Episode Listen Later Jan 9, 2025 21:35


    Michael Heneka joins Chloe Wilson and Bea Gomez Perez-Nievas of The Lancet to discuss a therapeutics paper discussing the opportunities and challenges of passive anti-amyloid β immunotherapy in Alzheimer's disease.Read the full article:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01883-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Nusrat Husain, Farah Lunat, and Fehmida Motala on postnatal depression in British south Asian women (the ROSHNI-2 trial)

    Play Episode Listen Later Oct 31, 2024 48:44


    ROSHNI-2 was a multicentre, randomised controlled trial that investigated the efficacy of a culturally adapted, cognitive behavioural therapy-based intervention for postnatal depression in British south Asian women. Joining us to share their expertise and perspectives are chief investigator Professor Nusrat Husain, trial manager Farah Lunat, and service user representative Fehmida Motala.Read the full article:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01612-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Rasha Al-Lamee and Shayna Chotai on ESC 2024 highlights

    Play Episode Listen Later Oct 10, 2024 40:18


    Rasha Al-Lamee and Shayna Chotai join Chloe Wilson of The Lancet to discuss ESC Congress 2024 highlights.The papers featured on this podcast are:1) https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01733-1/fulltext2) https://www.nejm.org/doi/abs/10.1056/NEJMoa24091343) https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01454-5/abstract4) https://www.nejm.org/doi/abs/10.1056/NEJMoa23143285) https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Elevated-Blood-Pressure-and-Hypertension6) https://www.jacc.org/doi/10.1016/j.jacc.2024.08.027Continue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Dr Oriol Mitjà and Dr Hypolite Muhindo Mavoko on mpox

    Play Episode Listen Later Sep 5, 2024 26:26


    On August 14th, the World Health Organisation declared a public health emergency of international concern in relation to mpox. This was motivated, in part, by the emergence of a concerning new strain of mpox, clade 1b, which has spread rapidly across Central Africa. Joining me this week to discuss important clinical aspects of the current mpox outbreak are Dr Oriol Mitja, Associate Professor at the Germans Trias Research Institute in Barcelona, and Dr Hypolite Muhindo Mavoko from the Department of Tropical Medicine at the University of Kinshasa.Continue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Natasha Pocovi on the prevention of low back pain recurrence

    Play Episode Listen Later Aug 8, 2024 23:50


    Natasha Pocovi joins Chloe Wilson of The Lancet to discuss a trial investigating a walking and education intervention for the prevention of low back pain recurrence in Australia (WalkBack).Read the full article:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00755-4?dgcid=buzzsprout_tlv_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Prasad Kulkarni on a vaccine against typhoid and paratyphoid

    Play Episode Listen Later May 2, 2024 18:06


    Prasad Kulkarni joins Callam Davidson of The Lancet to discuss the safety and immunogenicity of a bivalent conjugate vaccine against typhoid and paratyphoid, following the publication of a phase 1 trial.Read the full article:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00249-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Patricia Campbell and Frans Rutten on heart failure with preserved ejection fraction

    Play Episode Listen Later Mar 28, 2024 40:03


    Patricia Campbell and Frans Rutten join Chloe Wilson for an educationally-focused podcast, discussing the key messages for clinical practice on heart failure with preserved ejection fraction.Read the full Seminar:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02756-3/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Lene Seidler on umbilical cord management at preterm birth

    Play Episode Listen Later Dec 21, 2023 14:49


    Lene Seidler joins Callam Davidson of The Lancet to discuss umbilical cord clamping strategies at preterm birth following the publication of two systemic review and meta-analyses with individual participant data.Read the full articles:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02468-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancethttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02469-8/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Emily Chew on the future of treatments for geographic atrophy

    Play Episode Listen Later Oct 26, 2023 18:26


    Emily Chew joins Chloe Wilson of The Lancet to discuss the future of treatments for geographic atrophy following the publication of two randomised controlled trials of new drug treatments.Read the full article here:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01583-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Simon Kyle on a new effective treatment for insomnia

    Play Episode Play 42 sec Highlight Listen Later Aug 31, 2023 11:04


    Simon Kyle joins Gavin Cleaver of The Lancet to discuss his paper on sleep restriction therapy as a new effective treatment for insomnia.Read the full article:https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00683-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

    Verna Vanderpuye and Isabelle Soerjomataram on International Women's Day and cancer

    Play Episode Listen Later Mar 8, 2022 12:56


    On this International Women's Day,  Lancet editors and the co-chairs of the Women and Cancer Commission discuss the burden of women's cancer on society and reflect on the questions the Commission is trying to answer. 

    Nick James on the STAMPEDE trial

    Play Episode Listen Later Dec 23, 2021 14:56


    Nick James discusses the key messages of the recent report from the STAMPEDE trial platform and the success of this platform in advancing the treatment of prostate cancer 

    In conversation with... Jie Qiao (in English)

    Play Episode Listen Later Jun 2, 2021 16:41


    Helena Wang discusses The Lancet Commission on women's reproductive, maternal, newborn, child and adolescent health (RMNCAH) in China with author Professor Jie Qiao.

    In conversation with... Jie Qiao (in Chinese)

    Play Episode Listen Later Jun 2, 2021 16:37


    《柳叶刀》亚洲执行主编王辉对话《柳叶刀中国女性生殖、孕产妇、新生儿、儿童和青少年健康重大报告》共同主席乔杰院士。

    In Conversation With... Siobhan Quenby & Arri Coomarasamy on miscarriage

    Play Episode Listen Later Apr 26, 2021 18:27


    Siobhan Quenby & Arri Coomarasamy discuss the key findings from The Lancet's new Series on miscarriage.

    Muir Gray

    Play Episode Listen Later Feb 25, 2021 16:41


    On the 50th anniversary of the Inverse Care Law, Professor Sir Muir Gray joins Gavin Cleaver to discuss the continuing importance of the ICL, and notions of value and quality in health care.

    icl muir gray
    Mary Bassett

    Play Episode Listen Later Feb 11, 2021 25:20


    The Lancet's new Commission, Public Policy and Health in the Trump Era, looks back at the effects of the last four years on the health of the USA. One of the authors of the Commission, Mary Bassett (Harvard University) joins us to talk about the Commission findings and wider issues facing the USA.

    Richard Horton on the Oxford vaccine phase 3 trial

    Play Episode Listen Later Dec 8, 2020 11:32


    Editor-in-chief of The Lancet, Richard Horton, discusses the results of the Oxford vaccine's phase 3 trial.

    Renee Salas

    Play Episode Listen Later Dec 2, 2020 17:12


    Renee Salas, leader of the Lancet Countdown policy brief in the US, discusses the climate problems facing the US, the issues of the last four years, and the reasons to be optimistic about the future.

    Rafael Lozano and Margaret Kruk

    Play Episode Listen Later Sep 2, 2020 22:52


    Universal health coverage (UHC) is a vital facet of healthcare across the world, and a new Global Burden of Disease paper seeks to measure its spread. The Lancet spoke with  author Rafael Lozano and linked Comment author Margaret Kruk about efforts to analyse and measure UHC.

    Richard Horton

    Play Episode Listen Later Jul 20, 2020 11:23


    The Lancet Editor-in-Chief Richard Horton explains the current status of the Oxford and China COVID-19 vaccines, including an overview of current progress and the next steps for both.

    Kathleen O'Reilly and Stein Emil Vollset

    Play Episode Listen Later Jul 14, 2020 23:21


    The new Global Burden of Disease paper forecasts major alterations in worldwide population over the next few decades. We ask Kathleen O'Reilly, of LSHTM, how models are made and how you account for a changing world, and we speak with paper author Stein Emil Vollset of IHME about the implications of his predictions.

    Rosanna Peeling

    Play Episode Listen Later Jul 7, 2020 21:37


    Professor Rosanna Peeling discusses the implications of seroprevalence results from recent COVID-19 antibody studies.

    Bin Cao (in Chinese)

    Play Episode Listen Later Mar 9, 2020 18:11


    柳叶刀亚洲执行主编王辉跟曹彬教授关于2019冠状病毒感染住院患者临床发病过程和死亡危险因素的讨论

    Bin Cao

    Play Episode Listen Later Mar 9, 2020 11:16


    The Asia Executive Editor of The Lancet, Helena Hui Wang, chats with Bin Cao about clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China.

    Richard Horton, Sarah Dalglish, and Grace Gatera

    Play Episode Listen Later Feb 19, 2020 16:25


    Richard Horton, Sarah Dalglish, and Grace Gatera talk about the future for children alive today, alongside findings from the new Commission.

    The Gift

    Play Episode Listen Later Dec 20, 2019 9:14


    Preethi Ramchand reads her Wakley Prize-winning essay, The Gift.

    The double burden of malnutrition

    Play Episode Listen Later Dec 16, 2019 10:07


    Camila Corvalan and Sandro Demaio talk about malnutrition around the world, and discuss how obesity and undernutrition are part of the same problem.

    burden malnutrition sandro demaio
    The 2019 report of The Lancet Countdown on health and climate change

    Play Episode Listen Later Nov 14, 2019 36:44


    The Lancet's Tamara Lucas talks to Professor Hugh Montgomery and Professor Hilary Graham about this year's annual Lancet Countdown, and past twelve months of activity in climate change.

    Opioid use, treatment, and policy

    Play Episode Listen Later Oct 23, 2019 8:18


    Louisa Degenhardt analyses recent changes in opioid usage and talks about clinical and policy solutions, in a podcast to accompany The Lancet's Drug Use Series.

    Malaria eradication within a generation

    Play Episode Listen Later Sep 9, 2019 18:23


    Sir Richard Feacham discusses the prospects and benefits of eradicating malaria.

    The upstream determinants of health

    Play Episode Listen Later Aug 2, 2019 18:21


    Michael Marmot, author of the 2010 Marmot Review, and Elias Nosrati discuss the effects of punitive social policy and austerity on health equity in the USA and Europe.

    25 Years Since Cairo

    Play Episode Listen Later Jul 13, 2019 10:54


    To mark World Population Day, UNFPA executive director Dr. Natalia Kanem discusses progress made since the landmark 1994 Cairo conference on population and development, and her hopes for the future.

    Nerve transfer surgery for restoring upper limb movement

    Play Episode Listen Later Jul 7, 2019 15:35


    The Lancet's Senior Editor Jonathan Pimm talks with author Natasha van Zyl about the pioneering surgical procedure of transplanting nerves to restore function in the upper limbs.

    Mortality, morbidity, and risk factors in China

    Play Episode Listen Later Jun 24, 2019 20:12


    Helena Wang from The Lancet talks with Xiaofeng Liang from China CDC about China's major burden of diseases. This podcast is in Chinese.

    Mental health in conflict zones

    Play Episode Listen Later Jun 12, 2019 11:15


    Fiona Charlson and Mark van Ommeren talk about the hidden epidemic of severe mental health disorders in conflict zones.

    A Series on gender norms, equality, and health

    Play Episode Listen Later May 31, 2019 10:03


    Gary Darmstadt (Stanford University, USA) in discussion with Lancet Executive Editor Jocalyn Clark on the priority to transform gender norms and inequalities. The need for more action and accountability on gender equality is clear: introduction of the 2030 Agenda for Sustainable Development and the Universal Health Coverage goals demand greater attention to the social determinants of health, including gender, for the purpose of enabling all people to reach their full human potential.

    Mass gatherings medicine

    Play Episode Listen Later May 17, 2019 11:47


    A decade after H1N1 influenza threatened the 2009 Hajj pilgrimage in Saudi Arabia, Ziad Memish (Alfaisal University, and Ministry of Health, Riyadh, Saudi Arabia) discusses the future priorities for research and global collaboration in the emerging specialty of mass gatherings medicine.

    Prophylactic antibiotics for operative vaginal delivery

    Play Episode Listen Later May 14, 2019 10:51


    Marian Knight (University of Oxford, UK) discusses the ANODE trial, which highlights how prophylactic antibiotics given at 3 hours after birth can substantially reduce infection after operative vaginal delivery. The results should result in an updating of current clinical guidelines.

    Law, global health, and sustainable development

    Play Episode Listen Later May 2, 2019 21:47


    Lawrence Gostin (O'Neill Institute, Georgetown University, Washington DC, USA), and Luisa Cabal (UNAIDS, Geneva) discuss a new Lancet Commission which highlights how greater collaboration between the spheres of law and health could potentially lead to improvements in sustainable development and global health.

    Nutritional support for inpatients

    Play Episode Listen Later Apr 26, 2019 11:52


    Philipp Schuetz (University of Basel, Switzerland) discusses a pragmatic randomised trial that highlights the benefit of guided nutritional support for medical inpatients.  

    Postoperative pain management and opioids

    Play Episode Listen Later Apr 12, 2019 11:25


    Inappropriate use of opioids after surgery has contributed substantially to the global opioid epidemic. Lead author Paul Myles (Alfred Hospital and Monash University, Melbourne, Australia) discusses a new Lancet Series that proposes alternative approaches for pain management after surgery.

    A framework convention for alcohol control?

    Play Episode Listen Later Apr 7, 2019 11:27


    TH Lam (University of Hong Kong) discusses a proposal for an international framework convention for alcohol control, given the totality of recent evidence that there is no safe limit for alcohol consumption.

    c-Section in LMICs

    Play Episode Listen Later Mar 29, 2019 17:18


    Shakila Thangaratinam (Queen Mary University of London, UK) discusses a systematic review and meta-analysis which highlights the increased risk of perinatal trauma and mortality associated with C-section use in low income and middle income countries.

    Building a tuberculosis-free world

    Play Episode Listen Later Mar 20, 2019 27:49


    A new Lancet Commission maps out priorities in diagnosis, treatment, prevention, and advocacy efforts to end tuberculosis by 2030. Detailed discussion with two of the commissioners: UN Tuberculosis Special Envoy Eric Goosby, and Paula Fujiwara from the International Union against tuberculosis and lung disease. The podcast is introduced by Liz Zuccala from The Lancet.

    Communicating with children about life-threatening disease

    Play Episode Listen Later Mar 15, 2019 24:42


    Alan Stein, Brenda Kelly (University of Oxford, UK), and Ruth Bland (Royal Hospital for Children, Glasgow, UK) discuss a two-part Series that is helping to develop guidelines for health-care professionals and families concerning life-threatening conditions in children or their parents.

    Heart failure Series

    Play Episode Listen Later Mar 8, 2019 15:42


    Patrick Rossignol (University of Lorraine, Nancy University Hospital/INSERM, France) discusses recent progress and future challenges concerning heart failure, notably a widespread lack of implementation of established clinical guidelines.

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