Podcasts about Atrophy

In this episode, we discuss potential new treatments for geographic atrophy of age related macular degeneration with Dr. Jessica Randolph of Wagner Kapoor Institute in Richmond, Virginia.

Five years ago I ruptured my Achilles. When I finally started walking again, the muscle was just gone. That's atrophy — weakening from lack of use. I think our brains are going through the same thing because of screen time. I call it digital atrophy.If you're 16 and live to 80, that's 64 years. An hour a day of scrolling costs you 2.6 years of your life. Four hours a day — which is closer to reality for most of us — costs you 10.6 years.And it's not just the time. Three things are quietly atrophying:Focus. It takes 23 minutes to get into real deep work, but most of us check our phones every five.Creativity. Heavier phone use is linked to weaker performance on creative tasks — and AI is only accelerating that outsourcing of our thinking.Social skills. Eye contact, real conversation, asking for something in person — all harder when a screen does the talking for us.None of this is an accident. The addictive design isn't a bug, it's the feature.The fix is reps: real conversations, screen-free creative time, sitting with hard problems a little longer. Rebuild the muscle the same way you'd rebuild any other one.Go find your One Second of Strength — and be happy.3 S's!Subscribe, Share, 5 Stars!

Tax season looked different in 2026, and it's not just volume. In this episode, Damien Greathead and Penny Breslin unpack the real AI story inside accounting firms: a live test of Juno saved 25% of prep time, clients are submitting documents faster than ever, and AI meeting assistants are replacing manual notetaking. But the bigger conversation is about critical thinking. As AI handles more routine work, who's making sure your team can still spot the anomaly? Identify the conflict? Give a client a real perspective? Damien shares how Moneypenny is gamifying judgment, hiring non-accountants, and rebuilding firm roles around advisory rather than compliance. This is a practitioner episode — real tools, real results, real friction. If you're building or scaling a CAS practice, this one is essential listening.Thank you to our sponsors MoneyPenny, LLC. From bookkeeping and tax preparation to back-office support, MoneyPenny helps accounting firms increase capacity, improve efficiency, and grow with confidence. In This EpisodeWhy accounting firms are seeing earlier tax document submissions in 2025Live AI tax prep test: Juno delivers ~25% time savings, but still requires human reviewThe difference between OCR tools (Grunt Works, Shore Prep, 1040 Scan) and AI-layer toolsHow AI can find conflicting information across reports, workflows, and client communicationsThe 'trust but verify' mindset, and why anomaly-hunting beats confirmation-seekingGamifying critical thinking to keep accounting teams sharp in an AI-assisted environmentThe 80/20 rule: who will rise to the top as AI takes over routine tasksBuilding distinct firm roles: traffic cop, trusted advisor, tax expertWhy MoneyPenny is hiring data scientists instead of more accountantsConnect with the hosts on LinkedInDamien GreatheadPenny Breslin

In this lecture, Ian reflects on a visit to Yellowstone and the geyser Old Faithful as an image of how people can become strangely unimpressed by what is remarkable. He uses the response of a child who called it “medium” to introduce the theme of spiritual apathy.He explains that the message is based on Revelation 3:14–22 and is addressed to the church in Laodicea. The church appears comfortable, wealthy, and secure, but Jesus says they are actually poor, blind, naked, and lukewarm. Ian contrasts their self-assessment with Jesus' evaluation, which focuses on the condition of their affection for him.The lecture develops three main causes of apathy. First is the myopia of success, where comfort, abundance, and busyness cause people to lose sight of their dependence on God. Second is derailment by disruption, where interruptions to spiritual habits such as prayer and Bible reading make it harder to return to them. Third is undervaluing what is most important, which leads people to take God for granted and give him leftovers rather than their best.Ian says Jesus' words are both corrective and loving. The call is to be zealous and repent, not to remain indifferent. He emphasizes that Jesus still stands at the door and knocks, inviting renewed fellowship and a shared meal. The lecture ends with an appeal to respond to that invitation and seek prayer.

In this episode, we discuss 5 year results of the GALE study which demonstrated that earlier treatment with pegcetacoplan of geographic atrophy preserves more retinal tissue with Dr. Dilsher Dhoot, California Retina Consultants, Adjunct Clinical Assistant Professor Ophthalmology, Roski Eye Institute, Keck School of Medicine of USC.

A security guard at an assisted living home becomes concerned when one of the residents inexplicably goes missing. Music by CO.AG and The Lighthouse Keeper For access to my audiobook, go to patreon.com/acephale Merch: Acephale Store Buy my books on Amazon: The Acephale Volumes Book 1, SOLACE: A NOVEL Instagram: @acephalehorrorfiction Learn more about your ad choices. Visit megaphone.fm/adchoices

Cognitive Atrophy, Referral Incentives, Fragmented Care: Is Primary Care Inevitable or Fixable? Episode 519. Primary care physicians are leaving traditional practice for concierge medicine in visible numbers—and the question is whether that exodus is an unavoidable consequence of how the system is built, or something we've simply chosen not to fix. Stacey Richter talks with Dr. Lisa Rosenbaum, a cardiologist at Beth Israel Deaconess Medical Center (BIDMC) and national correspondent for the New England Journal of Medicine, who recently devoted an entire season of her NEJM podcast, Not Otherwise Specified, to the state of primary care. Together they test three forces reshaping the field—cognitive atrophy, referral incentives, and care fragmentation—against a single question: inevitable, or fixable? WHAT YOU'LL LEARN ✅ Why Dr. Lisa Rosenbaum calls the risk of "cognitive atrophy" among primary care physicians a generational threat rather than an individual one—and why she believes it is not inevitable ✅ How financial incentives that pay far more for a specialist visit than a primary care visit (roughly 5% of healthcare dollars for close to 35% of outpatient visits) structurally push referrals earlier and more often than necessary ✅ Why "relational expertise"—the judgment a doctor builds by knowing a patient over time—is, in Dr. Rosenbaum's view, primary care's real and undervalued skill set ✅ How care fragmentation, illustrated by Miriam Paramore's LinkedIn essay about her father's end-of-life care, leaves patients bouncing among specialists with no one taking ownership of the whole picture ✅ Why Dr. Rosenbaum argues that blaming everything on structural constraints "strip[s] ourselves of our own agency," and what she thinks physicians and healthcare buyers should each do about it WHY THIS MATTERS Roughly 70% of physicians are employed today, and about 5% of every healthcare dollar goes to primary care despite it covering close to 35% of all outpatient visits—numbers that, per Dr. Rosenbaum, reflect choices the system has made, not laws of nature. When primary care doctors lose the time and incentive to build relationships with patients, the system loses its quarterback, and patients end up fragmented across specialists with no one accountable for the whole picture. Dr. Rosenbaum's core argument is that none of this is inevitable, but fixing it requires both structural change and individual physicians and healthcare buyers reclaiming their own agency. MENTIONED IN THIS EPISODE EP504 with Ryan Jacobs: Apple Podcasts | Spotify | Other Apps EP473 with Kenny Cole, MD: Apple Podcasts | Spotify Other Apps EP391 with Scott Conard, MD: Apple Podcasts | Spotify | Other Apps Article: "Ordinary Rural Death: My Father's End-of-Life Journey" by Miriam Paramore EP409 with Larry Bauer, MSW, MEd: Apple Podcasts | Spotify | Other Apps === LINKS ===

Which imaging biomarkers matter most at diagnosis of GA, and how should they shape the decision to treat? In episode 1 of the GA in Practice miniseries on New Retina Radio, moderator Geeta Lalwani, MD, and panelists Murtaza Adam, MD, and Carl Danzig, MD, review the practical role of fundus autofluorescence and OCT in identifying high-risk GA, discuss ellipsoid zone integrity as an emerging endpoint, and work through a hypothetical case of an active, motivated patient with bilateral extrafoveal GA and good vision to explore how lifestyle, lesion characteristics, and patient education factor into early treatment decisions.

What stands between a patient with geographic atrophy and consistent, effective treatment? And how do clinicians bridge that gap? In episode 3 of the GA in Practice miniseries on New Retina Radio, moderator Geeta Lalwani, MD, and panelists Murtaza Adam, MD, and Carl Danzig, MD, address injection burden, insurance hurdles, and the role of patient education tools in supporting adherence. The group also weighs the potential for AI to guide treatment decisions and track progression, then works through a hypothetical case of an 82-year-old caregiver with bilateral diffuse trickling GA who is not yet motivated to pursue treatment.

How have 3 years of real-world experience with complement inhibition changed when and how retina specialists treat GA? In episode 2 of the GA in Practice miniseries on New Retina Radio, moderator Geeta Lalwani, MD, and panelists Murtaza Adam, MD, and Carl Danzig, MD, examine how referral patterns, safety data, and extension study findings have shifted their approach to early treatment. The group then works through a hypothetical case of an active 73-year-old patient with extrafoveal GA and intermediate AMD in the fellow eye, exploring how lesion characteristics, CNV risk counseling, and months-long travel schedules factor into the treatment decision.

In this episode, we review the evidence regarding the effectiveness of AREDS vitamin supplementation in affecting the growth of geographic atrophy in age related macular degeneration.

AI in Education and the Necessity of Liberal Learning. Guest: Peter Berkowitz. The rise of AI in academia tempts students to bypass the essential struggle of thinking, leading to intellectual atrophy. Educators argue that liberal education is now more vital than ever to help students cultivate a flourishing mind and recognize the limitations of technological shortcuts. 141910 VALENCIA

Thanks to our Partners, Pico Technology, and AutelWatch Full Video EpisodeIn this episode of Diagnosing the Aftermarket A to Z, Matt Fanslow starts with a case study on a 2000 Ford Excursion with a 7.3L Power Stroke that came in with a severe lack of power. What began as a fuel delivery problem turned into a more interesting diagnostic puzzle involving a P1280 injection control pressure sensor code, an aftermarket ICP sensor, and a fault that appeared to happen not during cranking or running, but after key-off.The case becomes a practical example of why testing under actual operating conditions matters. Static tests can pass, scan data can look normal, and a meter may never show the event. In this case, the scope captured something the rest of the tools could easily miss.Matt then shifts into a listener question about artificial intelligence, especially large language models like ChatGPT, Gemini, Claude, Grok, and others. The concern is not simply whether AI is good or bad, but whether people, especially kids, may begin outsourcing too much thinking, writing, problem-solving, and confidence to these tools.The episode lands on a recurring theme: tools are not the problem by themselves. The question is how they are used, what skills may atrophy when they are overused, and whether individuals, families, businesses, industries, and society are willing to think more carefully and evidence-first about the long-term effects.Topics Covered2000 Ford Excursion 7.3L Power Stroke Case StudyMatt discusses a 7.3L Power Stroke with a major lack-of-power concern. The initial issue was tied to the low-pressure fuel supply side. A basic fuel pressure test had passed, but it had not been tested under the actual conditions where the symptom occurred.That led to a larger point: testing at idle, key-on, or during cranking is not the same as testing under load.The vehicle ultimately had damaged pickup screens and debris in the fuel tank. Cleaning the tank and replacing the failed components solved the fuel supply issue, but another problem remained.The P1280 ICP Sensor ProblemAfter the fuel supply repair, the truck began setting a P1280 code, related to the injection control pressure sensor circuit reading low.The strange part was that the voltage looked normal:Key-on engine-off voltage looked normal.Cranking voltage did not drop.Five-volt reference stayed stable.Sensor ground stayed stable.The signal looked fine while running.The meter never really caught the failure.The scope eventually revealed the important event: after key-off, the ICP signal voltage would sometimes dip nearly to zero. That appeared to be enough for the PCM to set the code on the next key cycle.Scope vs. Meter vs. Scan ToolThis case is a useful reminder that each tool has limits.A scan tool may not refresh fast enough or may stop collecting data after key-off. A meter may technically sample quickly, but the display may not show a short event clearly. The oscilloscope was the tool that made the failure visible.The point is not that one tool is always better. The point is knowing which tool fits the question being asked.Aftermarket Sensor BehaviorThe aftermarket ICP sensor appeared to produce a rebound effect after shutdown. Matt compares the behavior to something like inertial rebound, a concept familiar from certain pressure pulse sensors and piezo-style tools.The OE Motorcraft sensor did not reproduce the same behavior. Replacing the aftermarket sensor with the OE sensor corrected the issue.Main Diagnostic TakeawaysTesting has to match the failure condition. A fuel pressure test that passes at idle does not prove the fuel system can keep up under load.A sensor can create a failure outside the moment most people are watching. In this case, the important event seemed to occur after key-off.A scope can reveal details that a scan tool or meter may miss, especially when the event is brief, intermittent, or happens outside normal observation windows.Aftermarket parts can fail in ways that are not obvious or traditionally “failed.” The sensor was not simply dead. It behaved incorrectly under a specific condition.Listener Question: AI, Kids, and Skill AtrophyThe second half of the episode deals with a listener question about artificial intelligence and whether it may negatively affect people, especially kids.Matt narrows the discussion to what most people mean by AI in everyday conversation: large language models. These tools can write, summarize, explain, organize, and suggest. That makes them useful, but it also creates a risk.The concern is skill atrophy. When people lean too heavily on AI to write, think, summarize, diagnose, or explain, they may lose confidence or sharpness in those same areas.AI TakeawaysAI does not have to be viewed as the collapse of civilization, but it also should not be treated casually.The better question is not “Is AI good or bad?” It is: What happens when people outsource too much of their thinking to it?Matt argues for an evidence-based approach. Families, schools, businesses, industries, and society should be asking harder questions about long-term effects instead of simply letting the tools spread and hoping it all works out.Neuroplasticity matters here. Even if people become overdependent on AI, the brain can adapt again. Skills can be rebuilt. Confidence can be recovered. But that depends on whether people recognize the problem and choose to do something about it.Thanks to our Partner, Pico TechnologyAre you chasing elusive automotive problems? Pico Technology empowers you to see what's really happening. Their PicoScope oscilloscopes transform your diagnostic capabilities. Visit PicoAuto.comThanks to our Partner, AutelFrom drivability diagnostics and TPMS service to ADAS and advanced safety systems, Autel helps technicians follow OEM procedures and repair with confidence. Learn more at Autel.comContact InformationEmail Matt: mattfanslowpodcast@gmail.comDiagnosing the Aftermarket A - Z YouTube ChannelThe Automotive Repair Podcast Network: https://automotiverepairpodcastnetwork.com/Remarkable Results Radio Podcast with Carm Capriotto: Advancing the Aftermarket by Facilitating Wisdom Through Story Telling and Open Discussion. https://remarkableresults.biz/Business by the Numbers with Hunt Demarest: Understand the Numbers of Your Business with CPA Hunt Demarest. https://huntdemarest.captivate.fm/The Auto Repair Marketing Podcast with Kim and Brian Walker: Marketing Experts Brian & Kim Walker Work with Shop Owners to Take it to the Next Level. https://autorepairmarketing.captivate.fm/The Weekly Blitz with Chris Cotton: Weekly Inspiration with Business Coach Chris Cotton from AutoFix - Auto Shop Coaching. https://chriscotton.captivate.fm/Speak Up! Effective Communication with Craig O'Neill: Develop Interpersonal and Professional Communication Skills when Speaking to Audiences of Any Size. https://craigoneill.captivate.fm/

Welcome to the 36th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  This episode features a discussion with senior author Dr Carsten Finke of the Brain article entitled: Brain atrophy patterns in anti-IgLON5 disease We discuss a fascinating article which examines clinical and imaging data related to anti-Iglon5 disease. This valuable contribution to our understanding of this rare disease comprises data collected across multiple sites. Results identified distinct atrophy patterns in anti-IgLON5 disease, which closely mirror sites of pathophysiologic processes, including autoantibody binding and tau deposition. Check out the full article on the Brain website as part of the March 2026 issue: https://doi.org/10.1093/brain/awaf256 This episode was co-hosted, edited and produced by Michael and Adam Handel, co-produced by Xin You Tai and Antonia Johnston, original music by Ammar Al-Chalabi.

Send us Fan MailThis week on Just MS News, we look at nine MS stories from the week of June 15–21, 2026.Topics include hidden cognitive symptoms, brain atrophy research, cognitive testing and daily life, accessible travel, progression independent of relapse activity, PFAS exposure, vaccine safety, mobility technology, and early repair-focused stem cell research.Just MS News is built to help the MS community cut through the noise and follow the stories that matter.Covered this week:UB research targets hidden symptoms of multiple sclerosis https://www.buffalo.edu/ubnow/stories/2026/06/benedict-hidden-symptoms-ms.htmlUntangling Brain Atrophy in MS https://www.nationalmssociety.org/news-and-magazine/momentum-magazine/research-and-science/untangling-brain-atrophy-in-msCan Cognitive Tests Predict Daily Life With MS? The Answer Is Yes, But Not Perfectly https://www.zmescience.com/science/news-science/can-cognitive-tests-predict-daily-life-with-ms-the-answer-is-yes-but-not-perfectly/10 MS Accessible Travel Planning Tips https://www.nationalmssociety.org/news-and-magazine/momentum-magazine/living-well/plan-an-accessible-escapeComorbidities for Predicting Progression Independent of Relapse Activity in Multiple Sclerosis Treated With B-Cell Depletion https://pubmed.ncbi.nlm.nih.gov/42226439/PFAS “forever chemicals” may be linked to multiple sclerosis, especially in women https://usrtk.org/healthwire/pfas-forever-chemicals-linked-to-multiple-sclerosis-especially-in-women/Measles, chickenpox vaccines not tied to relapse in people with multiple sclerosis https://www.cidrap.umn.edu/measles/measles-chickenpox-vaccines-not-tied-relapse-people-multiple-sclerosisParalyzed Minnesota man's invention aims to help people with mobility issues walk again https://www.cbsnews.com/minnesota/news/walkport-invention-mobility-issues/NewcelX Stem Cell Platform Strengthened by Peer-Reviewed AstroRx Study in Multiple Sclerosis https://www.tipranks.com/news/company-announcements/newcelx-stem-cell-platform-strengthened-by-peer-reviewed-astrorx-study-in-multiple-sclerosisOne week of MS news. One calm place.The Just MS (Multiple Sclerosis) Show, w host Justin Loizos, is a podcast that connects, educates and tries to uplift others living with multiple sclerosis. It provides real-life stories, interviews, and information about DMTs (disease modification therapies) and updates on research developments.www.justmultiplesclerosis.com

In our latest episode we discuss the results of a novel approach to the treatment of geographic atrophy using Xelafaslatide a Fas inhibitor with Dr. David Zacks, Professor of Ophthalmology at the Kellogg Eye Center at the University of Michigan.

Clinical trials are essential to advancing care for age‑related macular degeneration (AMD) and geographic atrophy (GA). In this episode, Mathew MacCumber, MD, PhD, explains how clinical trials work, the potential benefits and challenges of participation, and key factors to consider when deciding whether a trial may be right for you. The discussion will also include a high-level overview of the GALLOP clinical trial for GA and what current research means for the future of vision health.

In the age of AI, do you feel that your future is more uncertain?

Dr. Alex Menze and Dr. Kathryn C. Fitzgerald discuss using accelerometry to detect subtle, longitudinal changes in disability in people with multiple sclerosis and how these changes relate to brain atrophy and disability progression.  Show citation:  Fitzgerald KC, Sanjayan M, Dewey BE, et al. Association of Changes in Activity Patterns With Brain Atrophy and Disability Progression in People With Multiple Sclerosis. Neurology. 2026;106(7):e214678. doi:10.1212/WNL.0000000000214678  Show transcript:  Dr. Alexander Menze: Hi, this is Alexander Menze. I just finished interviewing Kate Fitzgerald for the Neurology Podcast. For today's Neurology Minute, Kate, I'm hoping you can tell us the main points of your paper. Dr. Kathryn C. Fitzgerald:  So we followed 238 people with MS who are 40 or older for over three years and they wore risk-worn accelerometers roughly every three months and had regular clinical assessments and brain MRI. And what we found was that changes in activity patterns over time at the individual level were associated with subsequent changes in disability worsening and brain volume loss, particularly in the deep gray matter and thalamus. Dr. Alexander Menze: Thank you very much. Be sure to download this week's podcast to hear our full interview.  

Welcome to MENO — your go-to for perimenopause, menopause, and everything in between. Is your sexual health stuck in "low-flow" mode? Most women don't realize that blood flow to the clitoris drops significantly after age 25. Lana Kerr, the creator of CO2LIFT, joins us for a world-first live demo of the carboxytherapy gel that is reversing vaginal atrophy, ending painful sex, and restoring sensation for women (and men) at any age. IN THIS EPISODE, WE COVER: The "Flaccid Clitoris": Why blood flow is the secret to sensation. Carboxytherapy 101: How CO2 triggers rapid tissue regeneration. Menopause & Cancer Recovery: Reversing dryness without hormones. Lichen Sclerosus: A non-invasive hope for chronic vulvar conditions. Live Demo: Watch exactly how to apply CO2LIFT for face and pelvic health. TIMESTAMPS: 0:00 – The "Flaccid Clitoris" Hook 0:02:47 – LIVE DEMO: How Carboxytherapy regenerates skin 0:12:58 – From Painful Chore to Pleasure: Lana's Backstory 0:26:46 – Hand Demo: Watch the instant "Glow" effect 0:32:51 – CO2LIFT for Men: Performance & Sensation 0:38:26 – Beyond Beauty: Medical uses for carboxytherapy 0:45:15 – Lichen Sclerosus: Relief for chronic vulvar pain 0:49:01 – Cancer Survivors: Restoring intimacy after chemo 0:54:16 – Mask Removal & Final Results RESOURCES: Shop CO2LIFT: https://co2lift.com/ Follow Lana Kerr: @thelanakerr Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Alex Menze talks with Dr. Kathryn C. Fitzgerald about using accelerometry to detect subtle, longitudinal changes in disability in people with multiple sclerosis and how these changes relate to brain atrophy and disability progression.  Read the related article in Neurology®.  Disclosures can be found at Neurology.org. 

Recently, Deloitte and Zoom announced they are slashing parental leave, PTO, and pension accruals. At the same time, Meta and Zuckerberg are implementing aggressive AI surveillance to "harvest" employee patterns and train their AI models. All the while, they preach human-centricity, but their actions tell a very different story.In this week's episode, I'm continuing the series on Fortifying Organizational Fragility. Last week, we declassified the "Rat's Nest" of our technical infrastructure. This week, we are looking at what appears to be the final severance of the social contract. We are moving into a dangerous era where employers ask for loyalty they haven't earned, and employees are incentivized to become "Intellectual Mercenaries" as they fend for themselves while their core cognitive skills begin to atrophy.The Declassification: The Dual Spiral of Human CapitalI break down two parallel journeys that have led us to this point of no return:​From Partner to Training Set: We've evolved from lifetime employment to career mobility, and now into the Mercenary and Mining Era. We are treating talent as a service while simultaneously mining them for the data that will eventually be used to replace them.​The Cognitive Decay Spiral: As the half-life of skills shrinks, many have reached a "Why Bother?" phase, believing any new skill will be vaporized by AI before it can be mastered. This leads to offloading 100% of our thinking to tools, causing our durable skills to atrophy.The "Now What": 3 Surgical Moves to Reclaim the FoundationUnfortunately, this entire trajectory is a ruse, a Ponzi scheme built on the impossible idea of a "lights-out" office that requires no human judgment. To survive the coming "Digital Tornado," you must take action today:​Close the "Say/Do" Gap: Stop participating in the drift toward treating employees as disposable line items. Re-establish agency by being open and honest with your teams about the environment you are in, rather than pretending the status quo is fine.​The Durable Skill Audit: You must deeply understand what work actually happens in your organization. Separate the "Perishable" tasks that AI can handle from the Durable Skills that are actually exploding in value.​Establish a Trust Anchor: You cannot "Ctrl+Z" shattered trust, but you can start building a new social contract based on mutual resilience. Work with your people to maximize the current environment, investing in them as individuals so they are anchored by purpose rather than just a paycheck.By the end of this episode, I hope to challenge you to hit the brakes on this corrosive trajectory. The future we're headed toward doesn't have to be tragic, but it will be if we continue to ignore the atrophy happening right under our noses.⸻If this conversation helps you think more clearly about the future we're building, make sure to like, share, and subscribe. You can also support the show by buying me a coffee at buymeacoffee.com/christopherlindAnd if your organization is wrestling with how to lead responsibly in the AI era, balancing performance, technology, and people, that's the work I do every day through my consulting and coaching. Learn more at christopherlind.co⸻Chapters00:00 – Benefit Cuts & AI Surveillance: The New Social Contract03:00 – The Journey of Human Capital: From Partner to Mercenary09:40 – The Cognitive Decay Spiral: The "Why Bother?" Phase15:50 – The Fallout: Shattering Trust Beyond Repair18:50 – The Ruse: Why the "Lights Out" Office is a Ponzi Scheme20:45 – Why You Can't "Ctrl+Z" This Culture23:00 – Step 1: Closing the "Say/Do" Gap25:00 – Step 2: The Durable Skill Audit27:45 – Step 3: Establishing the Trust Anchor31:00 – Conclusion: Fortifying the Foundation#FutureFocused #Leadership #HumanCapital #CognitiveAtrophy #FutureOfWork #AI #OrganizationalFragility #ChristopherLind #DurableSkills #TrustEconomy

Is excess body fat a literal "brain-drain"? We dive into the science of neuro-protection, looking at how maintaining a healthy body composition might prevent the premature aging of the brain. This session examines the causal mechanisms behind cognitive decline and why metabolic fitness is just as important for your IQ as it is for your physique.Thank you for listening to Psychology Celebrity Pulse. This episode is for educational and entertainment purposes only and is not a substitute for professional mental health care or diagnosis. We do not diagnose public figures or provide individualized clinical advice. If you're struggling with mental health concerns, please reach out to a qualified licensed professional in your area. If you enjoyed today's discussion, please subscribe, rate, and review the show — it helps others discover it. You can also follow us for updates on new episodes. We'll be back soon with more psychological insights on culture and celebrity. Until then, stay curious and take care.”

Part II: Cognitive Atrophy Is a Leadership Crisis: Mohan Nair on Why Healthcare's AI Obsession Is Costing Us Our Best Thinking Host Megan Antonelli, CEO of Health Impact Live, sits down with Mohan Nair, innovator, author, and former Chief Innovation Officer at Cambia Health Solutions, to explore what it truly means to stay human in an AI-obsessed world. Mohan's newest book, Unreachable: How Not to Lose Your Mind in an AI-Obsessed Era, is already an Amazon bestseller, and the conversation is as timely as it is thought-provoking. In this episode, you'll hear about: • Why AI adoption is creating cognitive atrophy and how the concept of ""inconvenient learning"" means removing friction from work may be costing us our most valuable skills • How healthcare leaders should distinguish between AI enablement and AI obsession, and why the physician-patient relationship remains fundamentally unreachable by any machine • Mohan's take on the rise of Chief AI Officers and how to find your own AI-unreachable value, the insights and instincts no technology can replicate Mohan's book, Unreachable: How Not to Lose Your Mind in an AI-Obsessed Era, is available now on Amazon and at BarnesandNoble.com in paperback and Kindle editions. Find all of our network podcasts on your favorite podcast platforms and be sure to subscribe and like us. Learn more at www.healthcarenowradio.com/listen/

In this episode we discuss the results of a phase 2 trial using subcutaneous elamipretide for the treatment of geographic atrophy with Dr. Mark Barakat.

Part I: Cognitive Atrophy Is a Leadership Crisis: Mohan Nair on Why Healthcare's AI Obsession Is Costing Us Our Best Thinking Host: Megan Antonelli Guest: Mohan Nair, CEO, Emerge Inc Join host Megan Antonelli, CEO of Health Impact Live, and guest Mohan Nair, innovator, author, and former Chief Innovation Officer at Cambia Health Solutions, to explore what it truly means to stay human in an AI-obsessed world. Mohan's newest book, Unreachable: How Not to Lose Your Mind in an AI-Obsessed Era, is already an Amazon bestseller, and the conversation is as timely as it is thought-provoking. Find all of our network podcasts on your favorite podcast platforms and be sure to subscribe and like us. Learn more at www.healthcarenowradio.com/listen/

Send us Fan MailIf you are a solo or small firm attorney trying to figure out where AI fits in your practice, this episode of LawLabs (a special series from the Modern Arizona Podcast) is your starting point. Carolyn Elefant breaks down exactly how to begin with AI tools, why most lawyers are evaluating them in the wrong order, and what the real risks look like when AI gets citations wrong. She also shares an honest prediction of where the profession is headed and why firms that are not adopting now will find themselves in a very difficult position within the year.Carolyn Elefant is the founder of the Law Offices of Carolyn Elefant and the creator of MyShingle.com, the longest-running blog dedicated to solo and small firm practice. A Cornell grad who started her firm in 1993, she has spent over two decades consulting, writing, and advocating for independent lawyers and is currently traveling the country speaking to attorneys about AI and its real-world impact on their practices.Topics discussed:Where lawyers should actually start with AI tools and what to avoid firstWhy you need to learn general AI tools before legal-specific onesHow to protect yourself from hallucinated and mischaracterized case citationsWhat the legal profession looks like in one year and in fiveWhy firms that are not using AI are running out of time to catch upFind Carolyn: MyShingle.com

Interview with Tiarnán D. L. Keenan, BM BCh, PhD, author of Modest and Variable Correlations Between Geographic Atrophy Enlargement Rates in Fellow Eyes in the AREDS2 Study. Hosted by Neil Bressler, MD. Related Content: Modest and Variable Correlations Between Geographic Atrophy Enlargement Rates in Fellow Eyes in the AREDS2 Study

Interview with Tiarnán D. L. Keenan, BM BCh, PhD, author of Modest and Variable Correlations Between Geographic Atrophy Enlargement Rates in Fellow Eyes in the AREDS2 Study. Hosted by Neil Bressler, MD. Related Content: Modest and Variable Correlations Between Geographic Atrophy Enlargement Rates in Fellow Eyes in the AREDS2 Study

Can you be terrified of the future and still move forward to build it?   In this episode of The OCD Whisperer Podcast, Kristina Orlova speaks with Dr. Lauren Cook, a licensed clinical psychologist and author of Generation Anxiety. Together, they explore the unique mental health pressures facing Gen Z and Millennials, and how to navigate big life transitions without letting anxiety hold the steering wheel.   Dr. Cook opens up about: • Her personal battle with Emetophobia (the fear of vomit) and how it nearly stopped her from becoming a mother. • The debilitating rituals and "Safety Taxes" that keep our worlds small. • Why ERP (Exposure and Response Prevention) is the gold standard for reclaiming your life from specific phobias. • Her journey to parenthood and how she manages anxiety while raising a family. • Why ERP (Exposure and Response Prevention) is the gold standard for reclaiming your life from specific phobias. • Her journey to parenthood and how she manages anxiety while raising a family.   Whether you're navigating a major life transition or struggling with a "hidden" phobia, this episode offers the psychological frameworks and distress tolerance tools you need to embrace the mess and find your liberated living.  

David Stamler, CEO of Alterity Therapeutics, is developing a drug to treat multiple system atrophy (MSA), a rare and rapidly progressing neurodegenerative disease that often presents as Parkinson's disease but is distinct and more aggressive. There is no single genetic cause or specific biomarker, making accurate diagnosis a significant challenge. The lead drug is a novel small molecule designed to manage excess reactive iron in the brain, which drives the disease, and may be effective for other neurodegenerative diseases involving iron dysregulation. David explains, "Multiple system atrophy is a rare disease, and that's part of the reason people may not know so much about it. It is a neurodegenerative disease, and as the name implies, there are multiple regions of the brain that are affected, hence the term multiple systems that are governed by those regions of the brain. And as the disease progresses, some of these regions degenerate, and you get abnormal function in various areas."   "Now, we like to characterize the disease as a Parkinsonian disorder, which means early on, it can look like Parkinson's disease. And that's kind of a good descriptor to help people understand what it might look like, but it's distinct from Parkinson's disease, and it progresses a lot faster, a lot more rapidly. So it's a disease that people don't know about, probably because no one famous has been diagnosed with MSA, although I'm sure various famous people have probably had the disease and maybe didn't know it."  #AlterityTherapeutics #MultipleSystemAtrophy #MSAAwareness #NeurodegenerativeDisease #Biotech #Phase3 #Neurology #MSA #ClinicalTrials #AlterityTherapeutics #ATH434 #Biotech #RareDisease #Neurodegeneration #DrugDevelopment #MedicalBreakthrough #IronChaperone Alteritytx.com Listen to the podcast here

David Stamler, CEO of Alterity Therapeutics, is developing a drug to treat multiple system atrophy (MSA), a rare and rapidly progressing neurodegenerative disease that often presents as Parkinson's disease but is distinct and more aggressive. There is no single genetic cause or specific biomarker, making accurate diagnosis a significant challenge. The lead drug is a novel small molecule designed to manage excess reactive iron in the brain, which drives the disease, and may be effective for other neurodegenerative diseases involving iron dysregulation. David explains, "Multiple system atrophy is a rare disease, and that's part of the reason people may not know so much about it. It is a neurodegenerative disease, and as the name implies, there are multiple regions of the brain that are affected, hence the term multiple systems that are governed by those regions of the brain. And as the disease progresses, some of these regions degenerate, and you get abnormal function in various areas."   "Now, we like to characterize the disease as a Parkinsonian disorder, which means early on, it can look like Parkinson's disease. And that's kind of a good descriptor to help people understand what it might look like, but it's distinct from Parkinson's disease, and it progresses a lot faster, a lot more rapidly. So it's a disease that people don't know about, probably because no one famous has been diagnosed with MSA, although I'm sure various famous people have probably had the disease and maybe didn't know it."  #AlterityTherapeutics #MultipleSystemAtrophy #MSAAwareness #NeurodegenerativeDisease #Biotech #Phase3 #Neurology #MSA #ClinicalTrials #AlterityTherapeutics #ATH434 #Biotech #RareDisease #Neurodegeneration #DrugDevelopment #MedicalBreakthrough #IronChaperone Alteritytx.com Download the transcript here  

Send us Fan MailPaper Discussed in this Episode:Assessing interstitial fibrosis and tubular atrophy in kidney biopsies artificial intelligence versus humans. Farris AB, Zukić D, Solez K. Current Opinion in Nephrology and Hypertension. March 16, 2026.Episode Summary: In this journal club deep dive on the Digital Pathology Podcast, we explore the intense debate over quantifying chronic kidney disease progression. We unpack a fresh 2026 study comparing artificial intelligence to human pathologists in assessing interstitial fibrosis and tubular atrophy. If top experts can't agree on a diagnosis due to human subjectivity, can an AI trained on their imperfect data provide a better standard? We explore what happens when pixel-perfect machines clash with nuanced human medical judgment.In This Episode, We Cover:• The Clinical Stakes of Kidney Scarring: Why interstitial fibrosis (the scarring of tissue spaces between filtering units) and tubular atrophy (shrinking and collapsing functional tubes) are the primary surrogate measures for tracking chronic kidney disease. We discuss how a mere 10% diagnostic variance can drastically alter a patient's medication regimen, dialysis prep, or transplant eligibility.• The Flaw in the "Gold Standard": We break down the "interobserver variability" problem—why two highly trained, board-certified pathologists can look at the exact same biopsy slide and give two completely different mathematical assessments of the damage.• How the AI Actually Works (Mapping the Neighborhood): A look at "indirect assessment through kidney compartment segmentation," where the AI acts as a digital surveyor. It identifies cellular fences like glomeruli and tubules, establishing microscopic "zoning laws" before it begins counting the damaged tissue.• The Proofreader vs. The Literary Critic: Why studies show a persistent "lack of complete concordance" between human and machine. We discuss how AI hyper-focuses on mathematical pixel intensity and mistakes physical slide artifacts (like a folded piece of tissue) for severe disease. Meanwhile, human pathologists act as "literary critics," easily filtering out the visual noise using clinical context.• The Humans + AI Synergy: The ultimate endgame isn't replacing pathologists, but combining the tireless mathematical consistency of AI with the complex contextual reasoning of humans to create a highly advanced co-pilot system.Key Takeaway: The lack of perfect agreement between AI and human pathologists isn't a failure, but rather evidence that they perform fundamentally different types of analysis. AI excels at tedious, reproducible quantification that eliminates human visual fatigue, but it lacks contextual judgment. By adopting a "humans + AI" workflow, the medical field can stabilize crucial kidney measurements and elevate the pathologist to a true diagnostic synthesizer, ultimately leading to more effective patient careSupport the showGet the "Digital Pathology 101" FREE E-book and join us!

This interview is brought to you in partnership with Eisai and is part of the Journey to Diagnosis series.Eisai: https://www.eisai.com/index.htmlJourney to Diagnosis: https://beingpatient.com/journey-to-diagnosis/Andrew Reid was 56 when he was diagnosed with early-onset Alzheimer's after unexplained changes that affected his work, driving, and daily functioning. He lives with a rare form of the disease called Posterior Cortical Atrophy (PCA), which primarily affects visual processing. Before his diagnosis, Andrew built a career in management and leadership as the founder and CEO of Big Fish Interactive, a leadership training firm focused on guiding organizations through positive change. He's also a gold medalist in the European Dragon Boat Championships. Andrew and his wife, Karina, are committed to sharing their story to educate others about early-onset Alzheimer's, reduce stigma, and amplify the voices of young families facing the disease. Andrew has found strength in an improv acting group and has become a passionate advocate for others living with young-onset Alzheimer's.In this conversation with Being Patient's Mark Niu, Andrew and Karina describe the emotional toll of uncertainty and the importance of getting the right diagnosis. They discuss the realities of living with PCA and strategies to make daily life safer and more manageable, from visual cues in the home to finding new forms of connection through humor, community, and creative outlets like improv. Together, they exemplify how resilience and support can help families keep moving forward even as the disease changes everyday life.------If you loved watching this Live Talk, visit our website to find more of our Alzheimer's coverage and subscribe to our newsletter: https://www.beingpatient.com/Follow Being Patient: Twitter: https://twitter.com/Being_Patient_Instagram: https://www.instagram.com/beingpatientvoices/Facebook: https://www.facebook.com/beingpatientalzheimersLinkedIn: https://www.linkedin.com/company/being-patientBeing Patient is an editorially independent journalism outlet for news and reporting about brain health, cognitive science, and neurodegenerative diseases. In our Live Talk series on Facebook, former Wall Street Journal Editor and founder of Being Patient, Deborah Kan, interviews brain health experts and people living with dementia. Check out our latest Live Talks: https://beingpatient.com/live-talks/

WarRoom Battleground EP 969: Soul of the Machine — Tech Money, Kill Bots, and Human Atrophy

The Hidden Danger of AI: Cognitive Atrophy | Coffee with KeysDescription: In this episode of Coffee with Keys, 19Keys breaks down the hidden danger of overusing artificial intelligence: cognitive atrophy.Referencing research on AI, writing, memory, and critical thinking, he explores how dependence on AI tools can weaken creativity, reduce recall, flatten originality, and train people to outsource their minds instead of sharpening them. This is a powerful reflection on the difference between using AI as a tool versus allowing it to replace human thought.19Keys also shares practical solutions for staying mentally sharp in the age of AI, including reflection, metacognition, reading, questioning, and thinking before prompting.This episode is a warning, a mindset shift, and a call to protect your natural intelligence in a world built for convenience.Learn more about SuperMind and support your cognitive wellness: asupermind.comJoin Ziion for exclusive community, deeper frameworks, and high-level content: ziion.ioSupport this podcast at — https://redcircle.com/19keys/exclusive-contentAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Join us as we reveal the Rock The Equinox lineup! We'll also be joined by Rok Fam, Amanda Teague-Roush. We'll also hear from Brian Zimmerman of the band Atrophy! Join us to find out with the local music community! CHEERS TO OUR PARTNERS: A massive thank you to the infrastructure of our community: Camp Mardi Gras, DEB Concerts, Rocklahoma Bitches, Photography by Angel Lee, AYS Rentals, ROK A Vet, Pryor Liquor, Big Ole Bus, Metal Corps Clothing, and Tannenbaum Graphics. Find all our links, including the Rocklahoma map, at our Linkspace: https://link.space/@Surviving Grab your official Surviving Rocklahoma Merch from Tannenbaum Graphics here: https://tannenbaum-graphics.printify.me/ And check out more of our official MCC Merch Store gear here: https://metalcorpsclothing.bigcartel.com/category/surviving-rocklahomaBecome a supporter of this podcast: https://www.spreaker.com/podcast/surviving-rocklahoma--4196214/support.Follow Us and Our Sponsors:Our Links: https://link.space/@SurvivingPhotography by Angel Lee: https://www.facebook.com/PhotographybyAngelLeeMetal Corps Clothing: https://metalcorpsclothing.bigcartel.com/category/surviving-rocklahomaTannenbaum Graphics: https://tannenbaum-graphics.printify.me

Tucson Thrash legends ATROPHY are back! Join Adam from Surviving Rocklahoma as he sits down with Brian Zimmerman to discuss the band's long-awaited return, the creative process behind their new album "Asylum," and the state of the metal scene in 2024.[Timestamps] 0:00 - Richmond Productions Intro 0:14 - Loud. Local. Live. 0:46 - Welcome & Sponsor Shoutouts 1:10 - Why Atrophy returned now 3:45 - Writing "Asylum": The Creative Process 7:20 - Photography Showcase: Atrophy Live 8:15 - Thrash Metal: 1980s vs 2024 11:30 - The New Lineup & Band Chemistry 14:50 - The Loyalty of the Metal Community 17:05 - Visuals: The Energy of the Stage 18:40 - What's next for Atrophy? 20:15 - How to submit to ROK THE BOX 21:30 - Final Cheers & Sponsors If you love Thrash Metal and supporting the local scene, make sure to: ✅ SUBSCRIBE for more artist interviews and metal coverage. ✅ LIKE this video to help the algorithm find more metalheads. ✅ COMMENT below: What is your favorite Atrophy track of all time?[ROK THE BOX - Submission Info] Want your music or band featured on the show? Submit your tracks to ROK THE BOX at: SurvivingRocklahoma@gmail.com#Atrophy #ThrashMetal #SurvivingRocklBecome a supporter of this podcast: https://www.spreaker.com/podcast/surviving-rocklahoma--4196214/support.Follow Us and Our Sponsors:Our Links: https://link.space/@SurvivingPhotography by Angel Lee: https://www.facebook.com/PhotographybyAngelLeeMetal Corps Clothing: https://metalcorpsclothing.bigcartel.com/category/surviving-rocklahomaTannenbaum Graphics: https://tannenbaum-graphics.printify.me

We discuss early studies of ophthalmic artery angioplasty in cases of advanced geographic atrophy with Dr. Philip Rosenfeld of the Bascom Palmer Eye Institute.

In our latest episode, we discuss the results of the PRIMA retinal implant in treating eyes with center involved geographic atrophy as presented in a recent New England Journal of Medicine article. 85% of eyes had meaningful improvement in vision at one year with Dr. Daniel Palanker, Professor of Ophthalmology and Electrical Engineering, Stanford University.

In this episode, we tackle one of the most frustrating and under-discussed parts of ACL rehab: your quad is still smaller months later, and you're wondering if something is wrong. I break down what the research actually shows about quadriceps muscle mass before surgery, immediately after, and even years down the road. We walk through why atrophy starts earlier than most people realize, why surgery creates a second drop, and why full visual symmetry is not guaranteed within 9–12 months. You'll also hear real-world examples from elite athletes, and why even world-class pros with top-tier resources don't always regain identical quad size quickly. We unpack graft type differences, genetics, programming mistakes, and the biological realities that shape muscle recovery. Most importantly, I explain why muscle size and strength are not a perfect one-to-one match using a simple “cup” analogy. Bigger muscle increases potential capacity, but performance depends on more than just volume. If you've been staring at your leg wondering why it still looks different, this episode gives you clarity, normalization, and practical direction on how to approach hypertrophy the right way.Ways we can connect:My IG: www.instagram.com/ravipatel.dptOur website: www.theaclathlete.comEmail: ravi@theaclathlete.com_________________Submit a topic or a question you'd like me to answer.Check out our website and tons of free ACL resourcesSign up for The ACL Athlete - VALUE Newsletter (an exclusive newsletter packed with value - ACL advice, go-to exercises, ACL research reviews, athlete wins, frameworks we use, mindset coaching, blog articles, podcast episodes, and pre-launch access to some exciting projects we have lined up)1-on-1 Remote ACL Coaching - A clear plan. Structured ACL program. Based on your goals. Expert guidance and support with every step. Objective testing from anywhere in the world.Send me a text and share anything about the podcast - an episode that hit home or how the podcast has helped you in your journey.

In this empowering episode, Dr. Anna Cabeca, The Girlfriend Doctor, sits down with internationally respected gynecologist and menopause expert Dr. Maria Sophocles to break the silence around vaginal and vulvar atrophy, hormonal shifts, and declining intimacy in midlife. They explore why pain, dryness, and loss of desire are often normalized—and how this fuels what Dr. Sophocles calls "The Bedroom Gap." You'll learn how hormones, anatomy, stress, and communication impact pleasure, plus evidence-based strategies to restore comfort, confidence, and connection at any age. Menopause is natural. Suffering is optional—and pleasure is your birthright.   ⏱️ Key Timestamps 00:00 – Welcome to The Girlfriend Doctor Show 01:45 – Why sexual medicine is missing from OB-GYN training 04:20 – What The Bedroom Gap really means 07:15 – Why women's sexual pain is often normalized 10:00 – The ABCs of sexual health: Acceptance, Being present, Communication 19:25 – Hormones, dryness, pain & loss of desire in midlife 23:10 – Vulvar anatomy & early signs women shouldn't ignore 28:15 – DHEA, estrogen & testosterone for tissue health 42:30 – Practical strategies to close the bedroom gap 58:00 – Reclaiming intimacy, confidence & pleasure at any age  

From the "Seduction Phase" of agentic AI to the terrifying prospect of human cognitive atrophy. We debate the rise of Claude Bot and local LLMs, breakdown Dario Amadei's warning of a "country of geniuses," and ask if we are becoming nothing more than "Meat AI." Plus, how to position your portfolio when capital eats labor.Welcome to the Alfalfa Podcast

Re-Air Date: 01–26-26 Original Air Date: 06-09-24 Unless you were a member in June of 2024, this episode of SOLVED! will be brand new to you! If you were a member back then, THANK YOU and this one is worth a re-listen. We're slowing down production for a little bit to reorganize our production processes, so enjoy this episode from our archives (and before YouTube) where Jay!, Amanda, Deon, and Erin discuss:   - How the media focus on the "politics" of an event trivializes the impact that event has on real people - The detrimental effects combining the daily news grind and the prioritization of profits forces has on news coverage - How keeping news coverage light and ignoring the effects of neoliberalism leaves desperate people vulnerable to fascism - The way history is repeating itself when it comes to news media not treating a demagogue's rhetoric as the emergency it is - The difference between symbolic beliefs vs factual beliefs   FOLLOW US ON: YouTube (This full episode premieres on YouTube on Friday - please share!) Bluesky Instagram Facebook Mastadon   REFERENCES: Why Americans Hate the Media - The Atlantic (1996) The Media Still Doesn't Grasp the Danger of Trump - The Intercept Don't Believe What They're Telling You About Misinformation - The New Yorker   TAKE ACTION: How to Support Minneapolis Communities In a blue state? Help stop ICE overreach No Kings Next Steps Free DC Project: FOR ALLIES ACROSS THE COUNTRY - Tell Congress to stand down the federal escalation One Million Rising Trainings Use the 5 Calls app for scripts and to reach all your elected officials Capitol Switchboard: 202-224-3121 Find your Indivisible group - or start one   Join our Discord Server Reach us via Signal: Bestoftheleft.01 Leave a message at 202-999-3991   Produced by: Jay! Tomlinson Thanks for listening! Visit us at BestOfTheLeft.com Contact me directly at Jay@BestOfTheLeft.com Review the show on Apple Podcasts!

Big changes at the Drafthouse, skill atrophy, and Dave Murray's forecast!- h3 full 2137 Tue, 13 Jan 2026 22:24:09 +0000 ugOf0uJXPOuSGe3rEKlMLsmnKIXAJ6GB comedy,religion & spirituality,society & culture,news,government The Dave Glover Show comedy,religion & spirituality,society & culture,news,government Big changes at the Drafthouse, skill atrophy, and Dave Murray's forecast!- h3 The Dave Glover Show has been driving St. Louis home for over 20 years. Unafraid to discuss virtually any topic, you'll hear Dave and crew's unique perspective on current events, news and politics, and anything and everything in between. © 2025 Audacy, Inc. Comedy Religion & Spirituality Society & Culture News Government False https://player.

Dr. Elizabeth Coon and Prof. Franziska Hopfner discuss the frequency and disease trajectory of MSA patients who do not experience dysautonomia, in comparison to those with autonomic involvement. Show citation:  Wilkens I, Bebermeier S, Heine J, et al. Multiple System Atrophy Without Dysautonomia: An Autopsy-Confirmed Study. Neurology. 2025;105(11):e214316. doi:10.1212/WNL.0000000000214316 Show transcript:  Dr. Elizabeth Coon: Welcome to the Neurology Minute. I'm Elizabeth Coon, and I'm delighted to welcome Professor Hopfner, who will give us a summary of her recently published paper in Neurology, "Multiple System Atrophy Without Dysautonomia and Autopsy Confirmed Study." Welcome, Professor Hopfner. Please tell us about this study and the key findings. Prof. Franziska Hopfner: So this work reframes how we think about MSA. So, autonomic failure is common but not universal and its absence does not rule out the diagnosis of MSA. So recognizing motor only in multiple system atrophy expands our diagnostic accuracy, improves patients consulting and broadens inclusions in future therapeutic trials. Dr. Elizabeth Coon: Excellent. Thank you. And thank you for listening to this Neurology Minute.

This is a free preview of a paid episode. To hear more, visit meetthemess.substack.comMove over, Meet the Press—it's time to MEET THE MESS!This week on the podcast, Jen and Karyn are joined by Fletch to unpack the horrifying story of an ICE agent who shot and killed an innocent woman in Minneapolis. Plus, hear about the growing threat of AI data centers to rural America, and why the USPS quietly changing postmark rules is a bigger deal than it sounds. And, Trump delivers (yet another) bananas message to Republicans that makes absolutely zero cents.On the lighter side, Jen shares her thoughts on Heated Rivalry and vaginal atrophy (as one does), John Mayer and McG swoop in to save Henson Studios, Will Smith gets sued by a violinist, and Taylor Swift's Eras Tour docuseries enters the group chat.On Meet the Mess, bestselling authors Jen Lancaster & Karyn Bosnak dive into the messiest news stories and hottest topics of the week to give a fresh and entertaining take on current events and life in general. An extended video version with the “Hot Mess of the Week” is available to paid Substack subscribers. Visit meetthemess.substack.com for more.Meet the Merch:• https://www.etsy.com/shop/MeetTheMessConnect with us on Instagram:• https://www.instagram.com/meetthemesspod• https://www.instagram.com/jennsylvania• https://www.instagram.com/karynbosnakConnect with us on TikTok:• https://www.tiktok.com/@meetthemess• https://www.tiktok.com/@karynbosnak

Many years ago in 2012, myself and a small team of people along with Coffee Fest Trade Shows had the pleasure of developing and running a competition called "America's Best Coffee House".  The first of it's kind team cafe competition that was, IMO, the most accurate to real cafe work competition ever made. To this day it remains unmatched in showcasing true-to-life barista skills that working baristas regularly engage in. We shipped and assembled on the show floor a fully functional coffee bar across the country 3x a year. (From POS, pour-over bar, back bar with sinks, front bar etc. the works!) Through a stringent application process including video submissions, written apps, and secret shopping, we invited cafe teams made up exclusively of 3 current baristas from that company to run this bar with a 10 min open shift, 30 min live bar serving actual customers from the show floor who also had weighted judging slips on their receipts, and a 10 min closing shift.  Along with our own standard cafe menu they were required to make, they brought their own coffee, sig drinks, pour over kettles etc. We had 3 judges judging all aspects of the competition and the teams never knew when the drinks they made would be judge by us since secret shoppers in the queue were instructed to deliver a range of drinks at random.   It was fantastic, complicated, effective, and expensive to produce (hence why we closed up shop in 2015) but the lessons we learned from the display of teamwork, cleanliness, communication, workflow, QC, hospitality, and more were incredible.  In this episode I am going to reminisce back to those competitions a bit and talk about the lessons and insights that were drawn from those intense real-life competitions and how they apply directly to your cafe. Will we ever see this competition rise up once more? Maybe not. But we can all raise our own standards and each pursue being the "Best Coffee House" where we are for the people we serve and serve with. Be sure to click the link below for a video produced during that time to see a slice of what we did. (Shout out to Joshua Boyt, Jesse Harriott, Jessica Rice, Terry Ziniewicz, Ryan Soeder, Pete Licata, Danny Loeschen, Aaron O'neal, and the Coffee Fest director at the time, David Heilbrunn.) We discuss: Integrity Real life vs on stage How time finds you out Prepare yourself for the unexpected You never know ow who is judging Team work Having a plan but being flexible Trusting the standards  Links: Video montage of America's Best Coffee House   Related Episodes:  492: How to be The Best Coffee Shop 298 : A Trophy, or Atrophy? SHIFT BREAK! Every Customer is a Judge   KEYS TO THE SHOP ALSO OFFERS 1:1 CONSULTING AND COACHING! If you are a cafe owner and want to work one on one with me to bring your shop to its next level and help bring you joy and freedom in the process then email  chris@keystothshop.com or book a free call now:  https://calendly.com/chrisdeferio/30min  SPONOR The world loves plant based beverages and baristas love the Barista Series!  www.pacificfoodservice.com

Dr. Elizabeth Coon talks with Prof. Franziska Hopfner aboutthe frequency and disease trajectory of MSA patients who do not experience dysautonomia, in comparison to those with autonomic involvement. Read the related article in Neurology®. Disclosures can be found at Neurology.org. 

Jack McMahon is an insightful author acclaimed for his book "Atrophy and Asymptotes," which intertwines philosophical ideas with personal narratives to explore themes of decline and limits. Drawing from his experiences, especially the loss of his brother and the challenges of the COVID-19 pandemic, McMahon uses the book as a means to confront his fears and strained family relationships, particularly with his daughter. Motivated by a desire to create a lasting legacy, he delves into topics such as the decay of American values, the rise of authoritarianism, and the importance of emotional responsibility in maintaining open communication and empathy. Through his narrative, McMahon also addresses societal issues like censorship, government overreach, and the strategic design of public spaces, using his platform to advocate for personal accountability and the preservation of fundamental freedoms.