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Welcome to the latest episode of 'On the Couch'. This occasional podcast series of chats with brokers, CEOs, and fund managers aims to give you an insight into the investing world. In this episode, I am talking to Jon Pilcher CEO of Neuren Pharma (NEU).Jon is an old friend, having chatted around 2-year ago about the exciting new drug and deal the company had done with Acadia on its 'Daybue' drug for Rett Syndrome. A lot has happened since then and plenty more to come.2025 is shaping up to be another good year for NEU. Cashed up with leverage to its new drug in trials NNZ 2591. A terrific opportunity to hear this success story first hand. Disclaimer: This is general advice only and you should consult your financial adviser regarding any of the thoughts, ideas or insights in this podcast. 

The US Market is closed overnight for the Memorial Day holiday and will resume trading on Tuesday US time; however, it is expected the rally will continue from last week as investors shrugged off inflation concerns on Friday in favour of market optimism from Nvidia's latest stellar results indicating earnings inflation over the next quarter. The futures market is trading higher across the key indices on Monday.Over in Europe on Monday, it was a quiet day for markets as the UK market was also closed for the late May bank holiday. Elsewhere in Europe, markets closed slightly higher to start the new trading week as investors continue searching for clues as to when the European Central Bank may cut interest rates. The STOXX600 rose 0.28%, while Germany's DAX and the French CAC each added 0.4% on Monday.The Asia markets also closed higher on Monday to start a data-heavy trading week in positive territory. China's industrial profits rose 4.3% year-on-year from January to April which boosted markets on Monday in a sign the world's second largest economy is making small yet material steps in the right economic recovery direction. China's CSI index rose 0.95% on the back of this data release, while Hong Kong's Hang Seng rallied 1.2% and South Korea's Kospi Index climbed 1.32%.The local market started the week in positive territory closing Monday's session up 0.8%, overcoming last week's inflation-driven sell-off, led by the real estate stocks rising 1.6% and telecoms stocks rallying 1.3%. The sell-off last week was driven by hotter-than-expected inflation driver data released in the US which pushed back investor hopes of rate cuts. Energy stocks came under pressure on Monday as the price of oil dipped to a near three-month low amid demand concerns out of the world's largest oil demand market, the US.Neuren Pharmaceuticals soared over 15% yesterday after the company resumed trading following a halt on the release of Phase 2 trial results showing significant improvement in Pitt Hopkins syndrome including key aspects of communication, social interaction, cognition, and motor abilities.Lendlease was another stand out on the local bourse yesterday rising almost 10% after the company revealed a strategic review to its global strategy, while online luxury fashion platform Cettire also soared over 10% after ‘categorically rejecting' allegations that customers purchased counterfeit products from its site.What to watch today:Ahead of Tuesday's trading session here in Australia, the SPI futures are expecting the ASX to open the day up 0.2% or 16 points to extend the rally of this week into another trading day.On the commodities front this morning oil is trading 1.08% higher at US$78.56/barrel, gold is up 0.84% at US$2353.01/ounce, and iron ore is up 0.11% at US$117.66/tonne.1 Aussie dollar is buying 67 US cents, 104.40 Japanese Yen, 52.09 British Pence and 1 New Zealand dollar and 8 cents.Trading Ideas:Bell Potter has maintained a buy rating on Neuren Pharmaceuticals (ASX:NEU) and has raised the 12-month price target from $26.50 to $28.00 on the neuro-developmental targeted pharmaceuticals developer following the release of the company's Phase 2 trials results showing a second positive read out for its drug candidate NNZ-2591 in Pitt Hopkins Syndrome. Bell Potter sees the value in the company's second drug candidate represents a similar, if not larger market opportunity than Rett Syndrome which Neuren's Daybue drug is on the market treating at present.Trading Central has identified a bearish signal on Hub24 (ASX:HUB) following the formation of a pattern over a period of 17-days which is roughly the same amount of time the share price may fall from the close of $41.53 to the range of $38.10 to $38.80 according to standard principles of technical analysis.

This month we feature three representatives from Neuren Pharmaceuticals to answer frequently asked questions about the recent Phase 2 clinical trial, and plans for a Phase 3. Larry Glass, Neuren's Chief Science Officer provides an insightful breakdown of NNZ-2591, the drug that was being tested. Additionally, Liza Squires, Chief Medical Officer, and Nancy Jones, VP of Clinical Development, offer an overview of the safety, tolerability, and efficacy results. Important links: Phase 2 top line results: https://pmsf.org/document/neuren-phase-2-trial-investor-presentation/?fbclid=IwAR2ytXd7HXVfjJ9hFxwUVlVgJvI_KkczBTpGJCNUOMLTzgUAI6lPy1ZZO9g Phase 2 inclusion and exclusion criteria https://clinicaltrials.gov/study/NCT05025241?cond=Phelan-mcdermid%20syndrome&term=NNZ-2591&rank=1#participation-criteria

Netball New Zealand is investigating a potential bid to host the 2031 World Cup. NNZ bid to host last year's World Cup but were pipped by Cape Town, with World Netball opting to have the sport's pinnacle event in Africa for the first time.

Netball New Zealand (NNZ) CEO Jennie Wyllie joins Martin Devlin on It's Only Sport, following the news that the position of Silver Ferns coach - currently held by Dame Noeline Taurua - is going to be advertised. NNZ held discussions with Taurua and came to the conclusion that opening the position to the public was the most appropriate step forward. Dame Noeline Taurua's contract is up at the end of the month and she has indicated her intention to reapply for the job. Wyllie talks to Devlin about how they came to the decision to open the job up and how difficult it was, the response from Taurua, whether or not they'd be happy having an overseas coach in charge of the Ferns, and more.

Het Groningse Noord Nederlandsche Zakkenhandel is in 100 jaar uitgegroeid naar NNZ Group met kantoren over de hele wereld. Het is al deze tijd ook binnen de familie gebleven. Maar hoe blijf je concurrerend? En wat te doen als Europa af wil van overtollige verpakkingen? Len Boot, algemeen directeur NNZ packaging network is te gast in BNR Zakendoen. Macro met Mujagić Elke dag een intrigerende gedachtewisseling over de stand van de macro-economie. Op maandag en vrijdag gaat presentator Thomas van Zijl in gesprek met econoom Arnoud Boot, de rest van de week praat Van Zijl met econoom Edin Mujagić. Boardroompanel Hoe is het pensioenfonds van DSM, dat een van de rijkste van Nederland was, een van de armste geworden? Dat en meer bespreken we dinsdag om 13.00 in het Boardroompanel met: - Rob van Eijbergen, hoogleraar integriteit aan de VU en organisatieadviseur - Steven Schuit, hoogleraar corporate goverance aan Nyenrode Business Universiteit SIF Het sociaal innovatiebond is ofwel SIF gaat na een pilot in 2022 verder en wordt uitgebreid. Zo krijgt het fonds van het ministerie van Sociale Zaken en Werkgelegenheid 2 miljoen euro om duurzame banen voor mensen met een afstand tot de arbeidsmarkt te creëren. Te gast is Rob Peelen van het Sociaal Innovatiefonds Zakenpartner Ze zakte af van het VWO naar VMBO-kader, behaalde uiteindelijke haar HAVO diploma. Ze studeerde Business Administration and Management aan de HvA, waarna ze een bachelor toegepaste psychologie volgde aan de UvA. Haar eerste baan in de recruitment vond ze verschrikkelijk en ze eindigde dan ook in een totaal andere hoek namelijk in de fashion. De zakenpartner van deze week is Lotte Vink, medeoprichter van Labfresh. Zakendoen met de Jurist Zakendoen kan vaak niet zonder enige juridische kennis. Daarom behandel ik in deze rubriek elke week een actueel dossier met een jurist uit het werkveld. Deze week heb ik het over Cookies en de privacy wetgeving AVG. Volgens de Belgische toezichthouder is het huidige systeem van toestemming vragen voor cookies, zodat adverteerders je internetgedrag kunnen volgen, niet wetmatig. En dat zou grote consequenties hebben! Vandaag met Charlotte Meindersma, jurist en expert op het gebied van auteursrecht en privacy Contact & Abonneren BNR Zakendoen zendt elke werkdag live uit van 12:00 tot 14:30 uur. Je kunt de redactie bereiken via e-mail en Twitter. Abonneren op de podcast van BNR Zakendoen kan via bnr.nl/zakendoen, of via Apple Podcast en Spotify.See omnystudio.com/listener for privacy information.

Waarom zijn komkommers altijd verpakt in plastic? En: wat kan een familiestatuut betekenen voor de continuïteit van een familiebedrijf? In ‘De Top van Nederland' een uitgebreid gesprek met Len Boot, algemeen directeur van verpakkingsbedrijf NNZ.  Abonneer je op de podcast  Ga naar ‘De top van Nederland' en abonneer je op de podcast, ook te beluisteren via Apple Podcast en Spotify. See omnystudio.com/listener for privacy information.

In this episode of On the Couch, I am joined by the CEO of one of the hottest biotech stories around currently, Jon Pilcher from Neuren (NEU).Jon joined Neuren in 2013 as CFO and was appointed CEO in May 2020. Before joining Neuren he was a member of the leadership team at Acrux throughout a period that included its IPO and listing on the ASX, the development and FDA approval of three novel pharmaceutical products and a transforming licensing deal with Eli Lilly in 2010. He formerly spent seven years in a series of senior financial positions in the R&D and corporate functions of international pharmaceutical groups Medeva and Celltech, which are now part of UCB. Jon is a Chartered Accountant and holds a degree in Biotechnology from the University of Reading in the UK.  He is a non-executive director of BTC Health.Neuren Pharmaceuticals (NEU) is developing new therapies for highly debilitating neurodevelopmental disorders that emerge in early childhood and are characterised by impaired connections and signalling between brain cells.Neuren's lead product trofinetide (also known as NNZ-2566) is licensed to Acadia Pharmaceuticals for North America, with Neuren retaining all rights outside North America and full access to all data generated by Acadia.If you enjoyed this podcast, why not sign up for a free trial? Get access to expert insights and research and become a better investor.There are also plenty of free podcasts from Marcus Today and the team covering daily updates, chats with fund managers and CEOs of companies that interest us.

The world champion Silver Ferns and New Zealand Men are set to go head-to-head again.The four-day Cadbury Netball Series, which will include the Silver Ferns, the New Zealand Men, an NZ A side and the New Zealand Under 21s, will offically go ahead at Fly Palmy Arena in Palmerston North from 21-24 October.Netball NZ Chief Executive Jennie Wyllie said she was looking forward to the series which had proven such a pivotal event last year."We're delighted to be able to confirm this series in such challenging and uncertain times," she said."The Cadbury Netball Series played such a big role in the Silver Ferns build-up to last year's successful Netball World Cup campaign and it will be instrumental again looking ahead to international games later this year."NZ Men's Junior Levi on defence against Silver Fern Jane Watson. Photo / PhotosportWyllie said the series would showcase the best netballers in the country going head-to-head while also mindful that the competition would play a part in the NZ U21 team's preparation for next year's Netball World Youth Cup in Fiji."This is an opportunity to see our elite athletes competing against each other and what better way for our Under 21 players to prepare for their pinnacle tournament than by taking on the best in the world," she said.Silver Ferns head coach Dame Noeline Taurua said the Cadbury Netball Series was another opportunity to grow their game."We need to stay ahead of the opposition so we can't bask in the glory of last year's Netball World Cup," Taurua said."We need to keep challenging ourselves and growing our game both on and off the court - we can't afford to be complacent."Taurua said she was looking forward to growing and developing the next level of players."This is not only for South Africa (Netball World Cup in 2023), but the cycle beyond," she said."While we want to continue with that explosive game and high tempo netball, we need to be patient and make sure we are growing the capability of our athletes at the rate they can handle it."The new Silver Ferns squad, which was announced last month, will go into camp next month to prepare.Plans for an international series are progressing as NNZ continues to work with the New Zealand Government to meet the requirements to safely host an international series later this year.

The Non-Neutral Zone cast has a great chat with special guest Rosalie Michaels.  Rosalie drops fun anecdotes and fantasy nuggets from start to finish in this edition of the NNZ.   She brings a unique view to the fantasy football landscape.  Her role as an analyst for Draft Kings helps her shed some light on both the daily fantasy game and redraft for our audience.