Podcasts about Stardust

"We proposed a concept to the American Society of Clinical Oncology (ASCO), recognizing that extravasation management requires significant interdisciplinary collaboration and rapid action. There can occasionally be uncertainty or lack of clear guidance when an extravasation event occurs, and our objective was to look at this evidence with the expert panel to create a resource to support oncology teams overall. We hope that the guideline can help mitigate harm and improve patient outcomes," Caroline Clark, MSN, APRN, AGCNS-BC, OCN®, EBP-C, director of guidelines and quality at ONS, told Chelsea Backler, MSN, APRN, AGCNS-BC, AOCNS®, VA-BC, oncology clinical specialist at ONS, during a conversation about the ONS/ASCO Guideline on the Management of Antineoplastic Extravasation. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by January 2, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to the management of antineoplastic extravasation. Episode Notes  Complete this evaluation for free NCPD. ONS/ASCO Guideline on the Management of Antineoplastic Extravasation ONS Podcast™ episodes: Episode 391: Pharmacology 101: Antibody–Drug Conjugates Episode 335: Ultrasound-Guided IV Placement in the Oncology Setting Episode 145: Administer Taxane Chemotherapies With Confidence Episode 127: Reduce and Manage Extravasations When Administering Cancer Treatments ONS Voice articles: Access Devices and Central Lines: New Evidence and Innovations Are Changing Practice, but Individual Patient Needs Always Come First New Extravasation Guidelines Provide Recommendations for Protecting Patients and Standardizing Care Standardizing Venous Access Assessment and Validating Safe Chemo Administration Drastically Lowers Rates of Adverse Venous Events This Organization's Program Trains Non-Oncology Nurses to Deliver Antineoplastic Agents Safely ONS books: Access Device Guidelines: Recommendations for Nursing Practice and Education (fourth edition) Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) Clinical Guide to Antineoplastic Therapy: A Chemotherapy Handbook (fourth edition) ONS courses: Complications of Vascular Access Devices (VAD) and IV Therapy ONS Fundamentals of Chemotherapy and Immunotherapy Administration™ ONS Oncology Treatment Modalities Clinical Journal of Oncology Nursing articles: Chemotherapy Extravasation: Incidence of and Factors Associated With Events in a Community Cancer Center Standardized Venous Access Assessment and Safe Chemotherapy Administration to Reduce Adverse Venous Events Oncology Nursing Forum article: Management of Extravasation of Antineoplastic Agents in Patients Undergoing Treatment for Cancer: A Systematic Review ONS huddle cards: Antineoplastic Administration Chemotherapy Immunotherapy Implanted Venous Port ONS position statements: Administration (Infusion and Injection) of Antineoplastic Therapies in the Home Education of the Nurse Who Administers and Cares for the Individual Receiving Antineoplastic Therapies ONS Guidelines™ for Extravasation Management ONS Oncologic Emergencies Learning Library ONS/ASCO Algorithm on the Management of Antineoplastic Extravasation of Vesicant or Irritant With Vesicant Properties in Adults American Society of Clinical Oncology (ASCO) Podcast: Management of Antineoplastic Extravasation: ONS-ASCO Guideline To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "The focus of this guideline was specifically on intravenous antineoplastic extravasation or when a vesicant or an irritant with vesicant properties leaks out of the vascular space. This can cause an injury to the patient that's influenced by several factors including the specific drug that was involved in the extravasation, whether it was DNA binding, how much extravasated, the affected area, and individual patient characteristics." TS 1:48 "The panel identified and ranked outcomes that mattered most with extravasation. Not surprising, one of the first was tissue necrosis. Like, 'How are we going to prevent tissue necrosis and preserve tissue?' The next were pain, quality of life, delays in cancer treatment: How is an extravasation going to delay cancer treatment that's vital to the patient? Is an extravasation also going to result in hospitalization or additional surgical interventions that would be burdensome to the patient? ... We had a systematic review team that then went in and summarized the data, and the panel applied the grading of recommendations, assessment, development, and evaluation (GRADE) criteria, grading quality of evidence and weighing factors like patient preferences, cost, and feasibility of an intervention. From there, they developed their recommendations." TS 7:35 "The panel, from the onset, wanted to make sure we had something visual for our readers to reference. They combined evidence from the systematic review, other scholarly sources, and their real-world clinical experience to make this one-page supplementary algorithm. They wanted it to be comprehensive and easy to follow, and they included not only those acute management steps but also guidance on 'How do I document this and what are the objective and subjective assessment factors to look at? What am I going to tell the patient?' In practice, for use of that, I would compare it to your current processes and identify any gaps to inform policies in your individual organizations." TS 16:34 "The guidelines don't take place of clinician expertise; they're not intended to cover every situation, but a situation that keeps coming up that we should talk about as a limitation, is we're seeing these case reports of tissue injury with antibody–drug conjugate extravasation. There's still not enough evidence to inform care around the use of antidotes with those agents, so this still needs to be addressed on a case-by-case basis. We still need publication of those case studies, what was done, and outcomes to help inform direction." TS 19:24 "Beyond the acute management is to ensure thorough documentation regarding extravasation. Whether you're on electronic documentation or on paper, are the prompts there for the nurse to capture all of the factors that should be captured regarding that extravasation? The size, the measurement, the patient's complaints. Is there redness? Things like that. And then within the teams, everyone should know where to find that initial extravasation assessment so that later on, if they're in a different clinic, they have something to go by to see how the extravasation is healing or progressing. ... I think there's an importance here, too, to our novice oncology nurses and their preceptors. This could be anxiety-provoking for the whole team and the patient, so we want to increase confidence in management. So, I think using these resources for onboarding novice oncology nurses is important." TS 22:34

Y con los de hoy serían 100 los discos internacionales que merecen una escuchadita para disfrutar de la buena añada musical de 2025.Playlist:DjRUM - Waxcap ('Under Tangled Silence')Ichiko Aoba - COLORATURA ('Luminescent Creatures')Oneohtrix Point Never - Waterfalls ('Tranquilizer')Nick León, Ela Minus - Ghost Orchid ('A Tropical Entropy')DJ Koze - Buschtaxi ('Music Can Hear Us')Jenny Hval - To be a rose ('Iris Silver Mist')Youth Lagoon - Lucy Takes a Picture ('Rarely Do I Dream')Maria Somerville - Garden ('Luster')Stereolab - Vermona F Transistor ('Instant Holograms On Metal Film')Florist - Have Heaven ('Jellywish')Σtella, Las Palabras - Baby Brazil ('Adagio')Molly Nilsson - How Much Is the World ('Amateur')Japanese Breakfast - Picture Window ('For Melancholy Brunettes (& sad women')Wednesday - Elderberry Wine ('Bleeds')Black Country, New Road - Besties ('Forever Howlong')Perfume Genius, Aldous Harding - No Front Teeth ('Glory')Cameron Winter - Love Takes Miles ('Heavy Metal')NewDad - Pretty ('Altar')Just Mustard - WE WERE JUST HERE ('WE WERE JUST HERE')John Glacier - Emotions ('Like A Ribbon')yeule - Evangelic Girl is a Gun ('Evangelic Girl is a Gun')Squid - Crispy Skin ('Cowards')Tennis - 12 Blown Tires ('Face Down In The Garden')Hamilton Leithauser - Knockin’ Heart ('This Side of The Island')Hotline TNT - Julia’s War ('Raspberry Moon')Model/Actriz - Cinderella ('Pirouette')Tyler, The Creator - Sugar On My Tongue ('DON'T TAP THE GLASS')Wet Leg - catch these fists ('moisturizer')SPRINTS - Descartes ('All That is Over')Tame Impala - My Old Ways ('Deadbeat')Amaarae - S.M.O ('BLACK STAR')Gelli Haha - Bounce House ('Switcheroo')Danny Brown, Underscores - Copycats ('Stardust')2hollis - flash ('star')Marie Davidson - Demolition ('City of Clowns')The Last Dinner Party - Count The Ways ('From The Pyre')Lily Allen - Pussy Palace ('West End Girl')Purity Ring - many lives ('purity ring')Oklou, Underscores - harvest sky ('choke enough')HAAi - Can’t Stand To Lose ('HUMANiSE')PinkPantheress - Illegal ('Fancy That')Escuchar audio

This week on the Primo show, Jesse and Katie discuss dark romance, Morning Glory Milking Farm, and a scandal at the 2025 dark rom con Sinners and Stardust. Plus, an FDB beef update. To hear more, visit www.blockedandreported.org

"They [monoclonal antibodies] are able to cause tumor cell death by binding to and blocking to necessary growth factor signaling pathways for tumor cell survival. That's going to be dependent on the target of the antibody, but I'll give an example of epidermal growth factor, or EGFR. This is overexpressed in several different kinds of cancers where activation of this growth factor increases the amount of proliferation and migration of cancer cells. So, if we bind to it and block to it, then that would help halt these pathways and stop cancer cell growth," Carissa Ganihong, PharmD, BCOP, oncology and bone marrow transplantation clinical pharmacist at Hackensack University Medical Center in New Jersey, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about monoclonal antibodies. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD) (including 45 minutes of pharmacotherapeutic content) by listening to the full recording and completing an evaluation at courses.ons.org by December 26, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge in the history of, the mechanism of action of, and the use of monoclonal antibodies in the treatment of cancer.  Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Pharmacology 101 series Episode 391: Pharmacology 101: Antibody–Drug Conjugates Episode 383: Pharmacology 101: Bispecific Antibodies Episode 375: Pharmacology 101: VEGF Inhibitors Episode 338: High-Volume Subcutaneous Injections: The Oncology Nurse's Role Episode 283: Desensitization Strategies to Reintroduce Treatment After an Infusion-Related Reaction Episode 275: Bispecific Monoclonal Antibodies in Hematologic Cancers and Solid Tumors ONS Voice articles: An Oncology Nursing Overview of Biosimilars Make Subcutaneous Administration More Comfortable for Your Patients Oncology Nurses' Role in Translating Biomarker Testing Results Reduce Chair Time by as Much as 16 Minutes by Priming IVs With Drug Shorter Administration Times Still Require High-Acuity Care The Names of Targeted Therapies Give Clues to How They Work ONS Voice drug reference sheets: Datopotamab deruxtecan-dlnk Enfortumab vedotin Margetuximab-cmkb Mirvetuximab soravtansine-gynx Nivolumab and hyaluronidase-nvhy Nivolumab and relatlimab-rmbw Pembrolizumab and berahyaluronidase alfa-pmph Retifanlimab-dlwr ONS book: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) ONS course: ONS Fundamentals of Chemotherapy and Immunotherapy Administration™ Clinical Journal of Oncology Nursing articles: Bolusing IV Administration Sets With Monoclonal Antibodies Reduces Cost and Chair Time: A Randomized Controlled Trial Management of Immunotherapy Infusion Reactions Nurse-Led Grading of Antineoplastic Infusion-Related Reactions: A Call to Action Safety and Adverse Event Management of VEGFR-TKIs in Patients With Metastatic Renal Cell Carcinoma Oncology Nursing Forum articles: Administration of Subcutaneous Monoclonal Antibodies in Patients With Cancer Depressive Symptoms and Quality of Life Associated With the Use of Monoclonal Antibodies in Breast Cancer Treatment ONS huddle cards: Bispecifics Checkpoint Inhibitors Monoclonal Antibodies Other ONS resources: Biomarker Database Bispecific Antibodies video Patient Education Sheets Antibodies article: A Comprehensive Review About the Use of Monoclonal Antibodies in Cancer Therapy Cureus article:  A Comprehensive Review of Monoclonal Antibodies in Modern Medicine: Tracing the Evolution of a Revolutionary Therapeutic Approach Association of Cancer Care Centers (ACCC) homepage Cancer Immunology, Immunotherapy article: Therapeutic Antibodies in Oncology: An Immunopharmacological Overview Drugs@FDA package inserts Future Oncology article: Biosimilars: What the Oncologist Should Know Hematology/Oncology Pharmacy Association homepage National Comprehensive Cancer Network homepage Network for Collaborative Oncology Development and Advancement (NCODA) subcutaneous therapy article Oncolink: Side Effects of Immunotherapy World Health Organization: New International Nonproprietary Names (INN) Monoclonal Antibody Nomenclature Scheme To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Prior to monoclonal antibodies, all we really had were these toxic chemotherapies or toxic radiation, so it was recognized how great it would be if we could have a treatment that was much more specific to the tumor cells and have agents that have less toxicities. These advancements in monoclonal antibody production began in the 1980s. ... Eventually, we had the first monoclonal antibody that was approved by the U.S. Food and Drug Administration (FDA) for an oncologic indication, rituximab." TS 4:14  "Nowadays, we do have treatments that are also considered tumor-agnostic. This is when a patient has a certain biomarker, then that treatment can be given and FDA approval was given, regardless what type of tumor the patient has. We typically see these kinds of tumor-agnostic therapies more so in patients who have recurrent or advanced diseases in solid tumors. One monoclonal antibody example that comes to mind is dostarlimab. That's a checkpoint inhibitor that's approved for patients who are deficient in mismatch repair mechanism." TS 23:48 "Our immune system constantly has this surveillance system and it's able to recognize foreign pathogens, abnormal cells, and even precancerous cells. And they're able to eliminate them before they become cancerous. But on the flip side, one of the regulatory mechanisms that we have so our immune system doesn't attack itself is the presence of checkpoints. When these checkpoints bind to their ligands, this can then act as an off switch so that, again, our immune system is not going to attack itself. But then the tumor cells can take advantage of this and actually use this mechanism to evade the immune system. So, when we're giving a checkpoint inhibitor, now we're removing that off switch. As a consequence, common adverse effects can include things like immune mediated adverse events. These most commonly affect the skin, gastrointestinal tract, and liver. Essentially, this can cause any '-itis' you can think of." TS 26:36 "Looking at strategies to prevent infusion reactions, one example is the use of premedication. If premedication is recommended, this typically includes any combination of antipyretics, which is typically acetaminophen. Antihistamine, which is typically an H1 antagonist like diphenhydramine. Although, there could be cases where we want to substitute this agent because maybe the patient has been tolerating therapy okay, and they're having a lot of side effects. So, we might use a second-generation antihistamine in some cases. The premedication may be given with or without some kind of steroid, whether that's methylprednisolone, hydrocortisone, or dexamethasone." TS 29:53 "We tend to think of monoclonal antibody usage to be primary oncology, but that's not really the case. The first monoclonal antibodies that were developed were not for oncologic indications, they were for transplant indication for cardiac indication. So, they're really diversely utilized across all specialties and medicines. We have monoclonal antibodies for hyperlipidemia, for neurology, for rheumatology, so the uses are so very expansive across all specialties." TS 41:01

In this special Xmas episode, John is joined by Adam Buxton and producer Joe Mount to discuss how they wrote, recorded and produced the album Buckle Up. Adam Buxton is a podcaster, actor, comedian and musician, best known for his long-running, award-winning Adam Buxton Podcast. Since launching in 2015, he's become one of the UK's most popular podcasters, with guests ranging from Paul McCartney to Tom Hanks. He's also appeared in films including Hot Fuzz and Stardust, and published two acclaimed memoirs. With his popular jingles at the heart of segments on his podcast and mid-2000s radio show, Adam began work on his debut record Buckle Up in 2022, enlisting Metronomy's Joe Mount as producer. Sitting down at Strongroom Studios, Adam and Joe dig into the sounds and ideas behind Buckle Up, exploring how to balance comedy with more serious songwriting, and why stripping back production can help reveal something more authentic. Tracks discussed: Dancing in The Middle, My Feelings, Skip This Track, Tea Towel GEAR GIVEAWAY COMPETITION Join the Christmas Giveaway on the Tape Notes Patreon Page TAPE IT Thanks to our friends at Tape It for supporting the podcast. Visit tape.it/tapenotes or use the promo code TAPENOTES in the app to get 20% off. QUBE Get 20% off at Qube Studio: https://www.theqube.com/ MAKENOISE PRO AUDIO Get 20% off all Franklin Audio products at https://makenoiseproaudio.com/ MUSIVERSAL Skip the waitlist and get your discount HERE LISTEN to ‘Buckle Up' here: https://lynkify.in/album/buckle-up/RmIMrCSB  Decca Records LINKS TO EVERYTHING TAPE NOTES   linktr.ee/tapenotes  Intro Music - Sunshine Buddy, Laurel Collective - https://lynkify.in/song/sunshine-buddy/YT47TLFI  GEAR MENTIONS The God Particle Soniccouture Native Instruments Roland System 100 Yamaha NS-10 Speakers Yamaha QY-20 Yamaha QY-70 Yamaha QY-100 Fender Stratocaster Tupperware Logic Pro OUR GEAR https://linktr.ee/tapenotes_ourgear HELP SUPPORT THE SHOW If you'd like to help support the show you can join us on Patreon, where among many things you can access full length videos of most new episodes, ad-free episodes and detailed gear list breakdowns. KEEP UP TO DATE For behind the scenes photos and the latest updates, make sure to follow us on:  Patreon: Tape Notes YouTube: Tape Notes Podcast Instagram: @tapenotes  Discord: Tape Notes To let us know the artists you'd like to hear, slide into our DMs, send us an email or even a letter. We'd love to hear!  Visit our website to join our mailing list: www.tapenotes.co.uk

"My 9th mix for my DJ residency at Stardust Radio Ibiza. You can listen to @ibizastardustradio by downloading the mobile app through the Apple or Android store, and these radio shows are also available streaming on SoundCloud and MixCloud from @ibizastardustradio. #djellisdee #progressivehouse #deephouse #melodichouse #ibizastardustradio #djmix #djset #ibizadj"

Heute spreche ich in meinem Perry Rhodan Reread-Podcast Stardust ruft Terra, über den 264. Band der Heftromanserie. Mit "Die Invasion der Toten" bringt Karl Herbert Scheer die CREST III zurück in die Heimat. Doch dort muss man herausfinden, dass man 50.000 Jahre zu früh kommt. Man findet die Milchstraße in einem Krieg gefangen, der bereits 92 Jahre tobt. Rhodan und Atlan müssen sich erst aus den übelsten Problemen herauslavieren, bevor man sich um die Rückkehr in die richtige Zeit kümmern kann. Wie die Geschichte ausgeht und der Roman bei mir ankommt, erfahrt ihr in diesem Podcast. Wenn ihr mehr über den Weltendieb oder Stardust ruft Terra erfahren wollt, besucht den Blog. Den Link findet ihr in den Shownotes. Wenn ihr Feedback oder eure Meinung mitteilen wollt, schreibt einen Kommentar im Blogpost oder schreibt eine Mail an stardustruftterra@weltendieb.com. Ihr findet mich natürlich auch auf allen gängigen sozialen Netzwerken. Einen Überblick über alle veröffentlichten Folgen des Stardust ruft Terra Podcast findet ihr unter diesem Link. Solltet ihr beim Hören dieser Episode Lust auf andere Perry Rhodan Podcasts bekommen haben, dann schaut auf jeden Fall im WarpCast vorbei und auch bei den Freunden des Radio Freies Ertrus. Die Intromusik stammt vom Künstler  Sergey Cheremisinov. Der Song heißt Jump In Infinity und unterliegt der Creative Commons Lizenz (CC BY-NC 4.0). Ihr könnt uns finanziell auf Steady unterstützen. Dadurch bekommt ihr zeitexklusiven Zugriff auf Podcastfolgen und andere Boni. Alle Podcasts des Weltendieb bleiben frei verfügbar. Alle weiteren Informationen findet ihr unter diesem Link.  Wenn ihr #PaxTerra Sticker haben wollt, schickt eine E-Mail an info@weltendieb.com. Vergesst dabei aber nicht eure Adresse.

342 Mission Stardust w/Mark HolmesSteven is joined by Mark Holmes to discuss 1967's Mission Stardust! We hope that you enjoy our discussion. We would also suggest watching the movie first, because we do disagree about certain things in the movie during our discussion.Please send feedback to DieCastMoviePodcast@gmail.com or leave us a message on our Facebook page.Thanks for listening!

Winter is arriving in the UK, so while Saul and Lucy hunker down, don layers and fire up the kettle more frequently than usual, what do their minds turn to in the garden? This is the perfect season for clearance of 2025 growth, for establishing new designs and for de-cluttering stores and greenhouses. Any hours that you can put into the garden now, will reward you hugely come spring and summer, when the jobs mount up. Quick - more tea and biscuits!Will it snow this Christmas? Will Saul ever manage to finally retrieve all his plants from Stonelands? Will Lucy push the John Deere to breaking point this time? Only listening to this final episode of 2025 will answer these burning questions, as we get the ever truly authentic recollections of the professional gardening life. More importantly, though - what do Lucy and Saul think of the predictions for 2026, set by the RHS (luckily, the year of the tomato and the year of the tropicals are both in there). It's unlikely that either podcaster will be piercing their water butt anytime soon, though...Instagram link:Lucy lucychamberlaingardensLinkedIn link:Saul WalkerIntro and Outro music from https://filmmusic.io"Fireflies and Stardust" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Support the show

"The thought of recurrence is also a psychosocial issue for our patients. They're being monitored very closely for five years, so there's always that thought in the back of their head, 'What if the cancer comes back? What are the next steps? What am I going to do next?' It's really important that we have conversations with patients and their families about where they're at, what we're looking for, and reassure them that we'll be with them during this journey and help them through whatever next steps happen," ONS member Clara Beaver, DNP, RN, AOCNS®, ACNS-BC, manager of clinical education and clinical nurse specialist at Karmanos Cancer Institute in Detroit, MI, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about prostate cancer survivorship considerations for nurses. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by December 19, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to survivorship nursing considerations for people with prostate cancer. Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Episode 390: Prostate Cancer Treatment Considerations for Nurses Episode 387: Prostate Cancer Screening, Early Detection, and Disparities Episode 201: Which Survivorship Care Model Is Right for Your Patient? Episode 194: Sex Is a Component of Patient-Centered Care ONS Voice articles: APRNs Collaborate With PCPs on Shared Survivorship Care Models Exercise Before ADT Treatment Reduces Rate of Side Effects Frank Conversations Enhance Sexual and Reproductive Health Support During Cancer Here Are the Current Nutrition and Physical Activity Recommendations for Cancer Survivors Nursing Considerations for Prostate Cancer Survivorship Care Regular Physical Activity and Healthy Diet Lower Risk of All-Cause and Cardiac Mortality in Prostate Cancer Survivors Sexual Considerations for Patients With Cancer Sleep Disturbance Is Part of a Behavioral Symptom Cluster in Prostate Cancer Survivors ONS course: Essentials in Survivorship Care for the Advanced Practice Provider Clinical Journal of Oncology Nursing articles: A Patient-Specific, Goal-Oriented Exercise Algorithm for Men Receiving Androgen Deprivation Therapy Incorporating Nurse Navigation to Improve Cancer Survivorship Care Plan Delivery Prostate Cancer: Survivorship Care Case Study, Care Plan, and Commentaries The Role of the Advanced Practice Provider in Bone Health Management for the Prostate Cancer Population Oncology Nursing Forum articles: A Qualitative Exploration of Prostate Cancer Survivors Experiencing Psychological Distress: Loss of Self, Function, Connection, and Control Identification of Symptom Profiles in Prostate Cancer Survivors Sleep Hygiene Education, ReadiWatch™ Actigraphy, and Telehealth Cognitive Behavioral Training for Insomnia for People With Prostate Cancer Understanding Men's Experiences With Prostate Cancer Stigma: A Qualitative Study Other ONS resources: Late Effects of Cancer Treatment Huddle Card Survivorship Care Plan Huddle Card Survivorship Learning Library American Cancer Society (ACS): Living as a Prostate Cancer Survivor ACS prostate cancer survivorship studies To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Some of the most common late side effects [are] urinary, bowel, and sexual dysfunction issues. For urinary effects, it can include urgency and frequency, some incontinence, or a weak or slow urine stream that frequently bothers the patient after treatment. Bowel effects can happen such as constipation, diarrhea, or inflammation of the rectum, which can lead to bleeding or mucus discharge. And then erectile dysfunction is another side effect that patients with prostate cancer often deal with and have to work with their physicians on, depending on what they want with that function. Fatigue, lymphedema, and skin changes can also occur after treatment." TS 1:40 "If we can catch [prostate cancer] and take care of it at an early stage, overall survival is about 90%. If the disease is localized, it's 99%. If we can take out the prostate, radiate the prostate, we can do something with that—localized, 99% survival rate. If there's regional metastasis, it's about 90%. And if there's distant metastasis, it's about 30% survival." TS 3:55 "Prostate cancer recurs in about 20%–30% of patients within the first five years of initial treatment. ... There's not a lot of research out there that shows what can reduce risk, but what has been shown to be effective is regular exercise, quitting smoking, and eating a healthy diet. ... It's really important for our patients to understand the importance of having follow-up visits so that we can catch a recurrence quickly instead of waiting years down the road. Prostate cancer is usually a slow-growing disease, so if we can pick it up quickly in those revisits, we can start another treatment for the patient." TS 6:00 "Sexuality is not something many people are comfortable discussing, but we really need to talk with patients and let them know that this is normal. It is normal that you may have some sexual dysfunction. It's normal that you may not feel the way you did before. Talk to us about it, let us know where you're at, let us know what your goals are, because there are a lot of things we can do. There are medications we can use for impedance. There are devices and implants available to help the patient to support them and give them whatever their goal is for their sexuality." TS 9:41 "Providing survivorship care plans are important for these patients—something that can be sent off to everyone else that's caring for that patient. You have your primary care physician, urologist, oncologist, the oncology nurse, maybe a navigator, and [others] who are looking into this patient. So, giving that patient a survivor care plan and putting it with their files to include a summary of the treatment received, because most of the time a patient is not going to remember exactly what they received. A suggested schedule for follow-up exams—so again, if a primary care provider is not used to dealing with a patient with prostate cancer, they have something to go off of. A schedule of other tests they may need in the future including screening for other types of cancer. Are they a smoker? Do they need lung screening? Do they need any other screenings related to types of cancers? And then a list of possible late or long-term side effects." TS 15:16 "I think a lot of people know about the long-term sexual effects, but what we don't really talk about is the effect that it has on the patient's self-image. How they define themselves, how they look, their body image, their self-image. It's really important that we continue to discuss it with patients and make them comfortable when discussing their sexuality and their goals for sexuality. They may be having these self-image issues after treatment that they're just not telling us about and that can affect their quality of life." TS 18:38

Réécoutez le FG spécial French Touch History (épisode 1) by DJ Ness du jeudi 18 décembre 2025DJ Ness présente FRENCH TOUCH VINTAGE MIX, un voyage dans la French Touch 1.0 avec des classiques et des raretés.. Au menu : Daft Punk, Bob Sinclar, Superfunk, The Supermen Lovers, Jess & Crabbe, Alex Gopher, Phunky Data, Didier Sinclair, Dax Riders, Demon, Fafa Monteco, Busta Funk, Nicholas, Gran Phabao, Modjo, Sebastien Leger, Cheek, Plaisir de France, Kojak, Dj Bertrand, DDD, Superfunk, Etienne de Crécy, Thomas Bangalter, Buffalo Bunch, Belamour, Stardust, Alan Braxe, Lifelike, DJ Falcon, Das Glow, Fantom

In this explosive episode of Gangland Wire, host Gary Jenkins sits down with actor, entrepreneur, and mob insider Gianni “Johnny” Russo, best known for his unforgettable role as Carlo Rizzi in The Godfather. Russo pulls back the curtain on a lifetime of stories that stretch from Frank Costello and Joe Colombo to Las Vegas skimming, the Vatican Bank, Marilyn Monroe, Jimmy Hoffa, and even Pablo Escobar. Russo discusses his new book, Mafia Secrets: Untold Tales from the Hollywood Godfather, co-written with Michael Benson—an unfiltered account of power, violence, politics, and survival inside the criminal underworld and Hollywood royalty. This is not recycled mythology—this is Gianni Russo's personal version of history from the inside. Whether you believe every word or not, the stories are raw, violent, and utterly fascinating. This episode discusses: The Godfather, The Kennedy assassinations, Vegas skimming, Marilyn Monroe, Jimmy Hoffa, the Chicago Outfit, Pablo Escobar

In the wake of a destructive attack, the crew comes up with a plan...   You do NOT need to listen to Overture to enjoy Anthem! If you have the appetite to listen to both, we recommend starting with Anthem, then going back to listen to Overture!   Gain access to an exclusive campaign, Shroud Over Saltmarsh, over on Patreon: https://legendsofavantris.com/patreon The Crooked Moon, a folk horror supplement for 5e, is available for preorder! Get the Crooked Moon at: https://thecrookedmoon.com/ Watch more D&D adventures in the world of Avantris live on Twitch: https://www.twitch.tv/legendsofavantris Check out our merch store: https://shop.legendsofavantris.com  Join our community on Discord: https://legendsofavantris.com/discord Watch our many campaigns on YouTube: https://legendsofavantris.com/youtube  All other links: https://linktr.ee/legendsofavantris   Watch the full episode here: https://youtu.be/hX9cE_YFGoI?si=s09CS_YTVG5qtloq

Winter is arriving in the UK, so while Saul and Lucy hunker down, don layers and fire up the kettle more frequently than usual, what do their minds turn to in the garden? This is the perfect season for clearance of 2025 growth, for establishing new designs and for de-cluttering stores and greenhouses. Any hours that you can put into the garden now, will reward you hugely come spring and summer, when the jobs mount up. Quick - more tea and biscuits!Many of our listeners will know Martin Fish from his wonderful podcast Pots and Trowels - a gardener very much anchored in the Northern climes of the UK but also a Senior Show judge, Gardens advisor for the RHS and former nursery man. Martin (along with his wide Gill) has been an ever present fixture at many Flower Shows and always has his finger on the pulse of gardening in this country. So we have a good chat about the state of horticulture especially at the Flower Shows and also a little insight into his new garden too.LinkedIn link:Saul WalkerInstagram link:Lucy lucychamberlaingardensIntro and Outro music from https://filmmusic.io"Fireflies and Stardust" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Support the show

"I'll go back to the backpack analogy. When your kids come home with a backpack, all of a sudden their homework is not on the desk where it's supposed to be. It's in the kitchen; it kind of spreads all over the place, but it's still in the house. When we give antibody–drug conjugates (ADCs), the chemotherapy does go in, but then it can kind of permeate out of the cell membrane and something right next to it—another cancer cell that might not look exactly like the cancer cell that the chemotherapy was delivered into—is affected and the chemotherapy goes over to that cancer cell and kills it," ONS member Marisha Pasteris, OCN®, office practice nurse in the breast medicine service at Memorial Sloan Kettering Cancer Center in New York, NY, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about ADCs in metastatic breast cancer. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  This podcast is sponsored by Gilead and is not eligible for NCPD contact hours. ONS is solely responsible for the criteria, objectives, content, quality, and scientific integrity of its programs and publications.  Episode Notes  This episode is not eligible for NCPD. ONS Podcast™ episodes: Episode 391: Pharmacology 101: Antibody–Drug Conjugates Episode 378: Considerations for Adolescent and Young Adult Patients With Metastatic Breast Cancer Episode 368: Best Practices for Challenging Patient Conversations in Metastatic Breast Cancer Episode 350: Breast Cancer Treatment Considerations for Nurses Episode 303: Cancer Symptom Management Basics: Ocular Toxicities ONS Voice articles: An Oncology Nurse's Guide to Cancer-Related Ocular Toxicities Black Patients With Metastatic Breast Cancer Are Less Informed About Their Clinical Trial Options Communication Case Study: Talking to Patients About Progressive Metastatic Breast Cancer What Is HER2-Low Breast Cancer? ONS Voice drug reference sheets: Belantamab mafodotin-blmf Datopotamab deruxtecan-dlnk Enfortumab vedotin-ejfv Fam-trastuzumab deruxtecan-nxki ONS books: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) Guide to Breast Care for Oncology Nurses Guide to Cancer Immunotherapy (second edition) ONS courses: ONS Fundamentals of Chemotherapy and Immunotherapy Administration™ ONS/ONCC® Chemotherapy Immunotherapy Certificate™ Clinical Journal of Oncology Nursing article: Antibody–Drug Conjugates and Ocular Toxicity: Nursing, Patient, and Organizational Implications for Care The Association Between Hormone Receptor Status and End-of-Life Care Among Patients With Metastatic Breast Cancer Oncology Nursing Forum article: Impact of Race and Area Deprivation on Triple-Negative Metastatic Breast Cancer Outcomes ONS huddle cards: Altered Body Image Huddle Card Chemotherapy Huddle Card Targeted Therapy Huddle Card Foundations of Antibody–Drug Conjugate Use in Metastatic Breast Cancer: A Case Study ONS Biomarker Database (refine by breast cancer) ONS Breast Cancer Learning Library American Society of Clinical Oncology (ASCO) homepage Drugs@FDA package inserts National Comprehensive Cancer Network homepage Susan G. Komen metastatic breast cancer page To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "What an ADC is doing is taking the antibody and linking it to a cytotoxic chemotherapy with the idea of delivering it directly into the cell. How I explain this to new nurses or patients is a backpack analogy. If we think of it as a HER2 molecule wearing a chemo backpack, it's going to find the HER2 receptor attached to it and then drop the chemotherapy into the cell via the backpack. Similar to how we come home from work, we open the key to our door, we're carrying all of our items, and then we drop our own personal items in our house." TS 2:30 "The reason that so many patients with metastatic breast cancer are able to receive ADC therapy is because they are targeting two very common antibodies that we see in breast cancer. One is HER2 and the other is trophoblast cell surface antigen 2 (TROP2). These are seen across the board. We see these on triple-negative breast cancers, hormone receptor–positive cancers, and HER2-positive breast cancers. And now we have a new way to talk about HER2, which is a HER2-low. ... Recently, we have found that patients who express low levels of HER2 are able to receive ADC therapy, specifically fam-trastuzumab deruxtecan." TS 4:21 "Another [ADC] that has just been approved is datopotamab deruxtecan. This is another ADC that targets the TROP2 receptor on a cancer cell. This one carries a lot of side effects. I mentioned earlier that you need an ophthalmology clearance because there is a lot of ocular toxicity around this one. We see a lot of blepharitis, conjunctivitis, there can be blurred vision. Another thing we monitor on this one is mucositis. In the package insert, there's a recommendation for using ice chips while receiving the treatment. ... Then in the HER2-positive and HER2-low space is the big one, which is fam-trastuzumab deruxtecan. This was approved in 2019 for the HER2-positive patients, then more recently in the HER2-low [patients]. The big [side effect] with this one is interstitial lung disease." TS 10:11 "Interstitial lung disease is an inflammation or a little bit of fibrosis within the lung that causes an impaired exchange between the oxygen and carbon dioxide. This was seen in the clinical trials, specifically around fam-trastuzumab deruxtecan. During the trials, they had a very small percentage, I think it was 1%, that died due to interstitial lung disease. So, this is a very important side effect for us as nurses to be aware of. It typically presents in patients like a dyspnea. A lot of times, it's like, 'Well, I used to be able to walk my kid to the bus stop, but now when I walk there, I feel really short of breath.' Or 'I've had this dry cough for the past couple weeks and I've tried medications, but haven't had that relieved.' So, we really need to be aware of that because early intervention in interstitial lung disease is key." TS 12:57 "ADCs are toxic drugs. They have the benefit of being targeted, but we know that they carry a lot of side effects. ... Their specificity makes them so wonderful and we've seen amazing responses to these drugs. But also, we want patients to be safe. We want to give these drugs safely. So, we have to assess our patients and make sure that this is an appropriate patient to give this therapy to. I think that's an open conversation that clinicians need to have with patients regarding these drugs." TS 18:08

This episode brings together the science, the medicine, and the lived experience behind BRCA mutations.  Emily Goldberg, JScreen's Director of Genetic Counseling Services, breaks down what these mutations are, how they're inherited, and what the actual cancer risks look like. Dr. Melissa Frey, a GYN oncologist at Cornell who works closely with high-risk families, walks us through what happens after someone tests positive — from screening to risk-reducing surgeries to the big conversations around fertility and timing. We also hear from Heather Boussi, who shares her powerful story of living with both BRCA1 and BRCA2 mutations. She talks about diagnosis, surveillance, surgeries, and how this all shaped her family-building decisions. Lastly, we look at what BRCA means for men, how that journey differs, and why PGT can still be an option. If you or someone you love is navigating this, we close with places to turn for support: JScreen, Sharsheret, I Was Supposed To Have A Baby, and Stardust (links below). It's a mix of expertise, honesty, and heart — the kind of conversation so many people wish they had heard earlier, especially when faced with such difficult decisions.  Note: This episode is the 4th of a series of 5 that we are collaborating on with Jscreen in 2025.  Take a look at our previous three episodes here : Episode 157: Introduction to Genetics and Infertility Episode 166: Fragile X Syndrome: A Silent Factor in Infertility Episode 185: It's Not Just Her: Male Factor Fertility and Genetics Uncovered Resources: Genetics and Personalized Cancer Prevention Program Facing Our Risk Empowered (FORCE) Jewish Fertility Foundation Stardust Foundation Sharsheret JScreen More about Emily Goldberg: Emily Goldberg serves as the Director of Genetic Counseling Services at jscreen, where she is dedicated to helping individuals understand and manage their genetic health. With dual bachelor's degrees in biology and psychology from Brandeis University and a master's degree in Human Genetics from Sarah Lawrence College, Ms. Goldberg has been a certified genetic counselor since 2011. Prior to joining jscreen, she worked at Montefiore Medical Center in the Bronx, specializing in prenatal and cancer genetics. In addition to her role at jscreen, Ms. Goldberg is committed to education, serving as an Instructor at the Albert Einstein College of Medicine and adjunct faculty at Sarah Lawrence College, where she teaches and mentors future genetic counselors. Her expertise and dedication make her a key member of the jscreen team. Connect with JScreen: - visit their website here - check out their Instagram   More about Melissa Frey, MD: Dr. Melissa Frey is an Associate Professor of Obstetrics and Gynecology in the division of Gynecologic Oncology and the Director of the Genetics and Personalized Cancer Prevention Program at Weill Cornell Medicine / NewYork Presbyterian Hospital. Dr. Frey's clinical care and research focus on the management of individuals with hereditary cancer syndromes (e.g. BRCA1, BRCA2, Lynch syndrome) and strong family history of breast and gynecologic cancers. She performs gynecologic cancer risk-reducing surgeries and is the principal investigator on several large trials aimed at cancer prevention among high-risk individuals. Dr. Frey has presented her research at national and international meetings and has more than 130 publications in peer-reviewed scientific journals. Connect with Dr. Melissa Frey: - check out her Instagram - view the Genetics and Personalized Cancer Prevention Program website   More about Heather Boussi :  Heather grew up in Westchester, NY and now lives in Englewood, NJ with her husband and three children. Her personal experience with hereditary cancer risk and genetic testing has made her a passionate advocate for awareness, education, and empowerment in women's health. Grounded in faith and family, Heather shares her story to help others approach life's challenges with strength, perspective, and gratitude. Connect with Heather: - check out Heather's Instagram   Connect with us: -Check out our Website -Follow us on Instagram and send us a message -Watch our TikToks -Follow us on Facebook -Watch us on YouTube -Connect with us on LinkedIn

SpaceTime with Stuart Gary - Series 28 Episode 145In this episode of SpaceTime, we explore groundbreaking discoveries that deepen our understanding of the origins of life and the dynamics of our galaxy.Sugars and Stardust: Insights from Asteroid BennuNASA's Osiris Rex mission has returned samples from the asteroid Bennu, revealing the presence of biologically essential sugars, including ribose and glucose, along with a unique gum-like substance never before seen in astromaterials. These findings, published in Nature Geoscience and Nature Astronomy, suggest that the building blocks for life were widespread throughout the early solar system. The discovery of ribose supports the RNA world hypothesis, indicating that RNA might have been the first genetic material. Additionally, the presence of glucose hints at the early energy sources available for life on Earth.Stars Defying the Black HoleAstronomers have observed numerous stars in stable orbits around Sagittarius A, the supermassive black hole at the center of our galaxy. This discovery, reported in Astronomy and Astrophysics, challenges previous assumptions that these objects were merely clouds of dust on a collision course with destruction. Instead, the new data from the ERIS Enhanced Resolution Imager and Spectrograph reveals a dynamic and stable environment around the black hole, providing a unique laboratory for studying interactions between black holes and stars.Martian Mystery Solved?A new radar technique employed by NASA's Mars Reconnaissance Orbiter has cast doubt on the existence of a suspected underground lake beneath the Martian South Pole ice cap. Initial signals that suggested the presence of liquid water have been reinterpreted as possibly being layers of rock and dust. This innovative approach opens new avenues for investigating subsurface resources on Mars, which could have significant implications for future exploration.www.spacetimewithstuartgary.com✍️ Episode ReferencesNature GeoscienceNature AstronomyAstronomy and AstrophysicsGeophysical Research LettersBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.

What a Creep Season 31, Episode 4Artie ShawThe lovely and fantastic Simone O. Elias, author of “Old Films, Young Eyes: A Teenage Take on Hollywood's Golden Age,” joins host Sonia Mansfield to talk about Artie Shaw.Artie Shaw played the jazz clarinet and was a big-band leader who reigned supreme as one of the kings of swing with his recordings of "Begin the Beguine," "Lady Be Good," and "Star Dust" in the late 1930s and 40s. He was also an abusive husband, who was married 8 times, ANNNND, he dropped some names at the House of Un-American Activities in the 1950s. What a creep.Sources for this episodeArtieShaw.comEbsco.comThe GuardianThe GuardianThe HairpinNew York TimesNew York TimesNPRSwing and BeyondTimeWikipediaWikipediaBe sure to follow us on social media. But don't follow us too closely … don't be a creep about it!Subscribe to us on Apple PodcastsFacebook: Join the private groupBlueSky Instagram @WhatACreepPodcastVisit our Patreon page: https://www.patreon.com/whatacreepEmail: WhatACreepPod@gmail.com We've got merch here! https://whatacreeppodcast.threadless.com/#Our website is www.whatacreeppodcast.com

Diane and Sean discuss the most charming yet underperforming movie of 2007, Stardust. Episode music is, "Coronation", by Ilan Eshkeri from the OST.-  Our theme song is by Brushy One String-  Artwork by Marlaine LePage-  Why Do We Own This DVD?  Merch available at Teepublic-  Follow the show on social media:-  BlueSky: WhyDoWeOwnThisDVD-  IG: @whydoweownthisdvd- Tumblr: WhyDoWeOwnThisDVD-  Follow Sean's Plants on IG: @lookitmahplants- Watch Sean be bad at video games on TwitchSupport the show

Kelsey recaps her family's epic Thanksgiving week in Orlando, Florida (November 2025), where 11 of them – her family of 5, her sister's family, and her parents – all shared a 7-bedroom house at Evermore Resort. With kids ranging from 4 to 13 years old, they packed in all the fun: Express Passes at Epic Universe, Universal Studios Orlando, and Islands of Adventure, plus lots of downtime enjoying their multi-generational home base at Evermore. Kelsey shares everything you need to know about staying at Evermore Resort, how Express Passes worked for their crew, what the parks were like over Thanksgiving week, and tips to help you decide if this kind of Orlando trip is right for you.If you'd like to share about your trip on the podcast, email me at: kelsey@triptalespodcast.comFollow me on Instagram: https://www.instagram.com/kelsey_gravesFollow me on TikTok: https://www.tiktok.com/@mskelseygravesJoin us in the Trip Tales Podcast Community Facebook Group: https://www.facebook.com/groups/1323687329158879Mentioned in this episode:- Travel planner Courtney Gibson: https://www.instagram.com/pixietravelbycourtney- Flip 7 card game: https://amzlink.to/az0ecfatrzQIM- Evermore Resort- Epic Universe with Express Passes- Ministry of Magic: Battle at the Ministry- Isle of Berk: Hiccup's Wing Gliders, Mead Hall for lunch- Celestial Park: Stardust Racers, Celestial Carousel- Super Mario Land- Dark Universe: Monsters Unchained, Curse of the Werewolf, Burning Blade Tavern- Helios Grand Hotel- Universal Studios Florida and Islands of Adventure: Butter Beer, Seuss Landing, VelociCoaster, Mythos Restaurant, Hogwarts Express, Universal's Holiday ParadeTrip Tales is a travel podcast sharing real vacation stories and trip itineraries for family travel, couples getaways, cruises, and all-inclusive resorts. Popular episodes feature destinations like Marco Island Florida, Costa Rica with kids, Disney Cruise Line, Disney Aulani in Hawaii, Beaches Turks & Caicos, Park City ski trips, Aruba, Italy, Ireland, Portugal's Azores, New York City, Alaska cruises, and U.S. National Parks. Listeners get real travel tips, itinerary recommendations, hotel reviews, restaurant recommendations, and inspiration for planning their next vacation, especially when traveling with kids.

"FUTURISMO IBIZA 022 hosted by CFBT on Ibiza Stardust Radio 04.12.2025 ""FUTURISMO IBIZA"" is a harmonious four-deck futuristic fusion of high-quality progressive and melodic house, where we take a monthly sonic journey from head to heart

"“Low lights, long echoes and late-night frequencies… this is minimal deep tech mix. No hype, no rush — just pulse, space and movement. If you feel it, you feel it. Let the rhythm take over.” Jaxx Noveira - Repeat Please (Extended Mix) Koog - I Can Be (Original Mix) Dennis Cruz - Rare Tape (Original Mix) Tonni (AR) - Grind (Original Mix) James B. - Obsolete (Original Mix) Emanuele Red - Red Rumble (Original Mix) Sixtee Seconds - Gentz (Original Mix) Dahaus, Axis Uno - Rest On The Week (Original Mix) Julian Kumar - Lie To Me (Original Mix) NoriKuest - Breakdown (Original Mix) Luciano Amaya - Floating Syntax (Original Mix) Carlo Gambino - Vibe Check (Original Mix) Azro, LOOPLION - Aliens In Chicago (Original Mix) Tuned in. Locked in. Minimal & deep tech transmission active. Rolling bass, stripped grooves, pure underground energy. Stay connected — no ads, just rhythm.

Join me and Travis as we discuss the new Danny Brown album Stardust

Winter is arriving in the UK, so while Saul and Lucy hunker down, don layers and fire up the kettle more frequently than usual, what do their minds turn to in the garden? This is the perfect season for clearance of 2025 growth, for establishing new designs and for de-cluttering stores and greenhouses. Any hours that you can put into the garden now, will reward you hugely come spring and summer, when the jobs mount up. Quick - more tea and biscuits!Podcast listeners have turned Lucy's head from the garden this week, as talk of her favourite biscuit reach a peak. But, she's regained her focus by making Christmas wreaths and playing with her new toy: the Scheppach RS400 compost sieve. Saul, meanwhile has been taking a spin in the Stonelands' 4x4, to source a Christmas tree for the family. He's also been attempting to extract himself physically and emotionally from the Stonelands estate - a process that is taking him longer than anticipated. Wisley glasshouse staff, watch out...LinkedIn link:Saul WalkerInstagram link:Lucy lucychamberlaingardensIntro and Outro music from https://filmmusic.io"Fireflies and Stardust" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Support the show

Hopefully our final fantasy

"Working as an oncology infusion nurse, being oncology certified, attending chapter meetings, going to ONS Congress® has really taught me plenty. But being an oncology patient taught me way more. I know firsthand the fears 'you have cancer' brings. Then going through further testing, CT scans, MRIs, genetics, the whole preparation for surgery was something I never considered when I treated a breast cancer patient," ONS member Catherine Parsons, RN, OCN®, told Valerie Burger, MA, MS, RN, OCN®, CPN, member of the ONS 50th anniversary planning committee, during a conversation about her experience being an oncology nurse and cancer survivor. Burger spoke with Parsons and ONS members Margaret Hopkins, MSN, RN, OCN®, HNB-BC, and Afton Dickerson, MSN, AGACNP-BCP, CBCN®, AOCNP®, CGRA, about how cancer survivorship has shaped their careers as oncology nurses and personal lives. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Episode Notes  This episode is not eligible for NCPD.  ONS Podcast™ episodes: 50th anniversary series Episode 385: ONS 50th Anniversary: Evolution of Cancer Survivorship Episode 263: Oncology Nursing Storytelling: Renewal Episode 253: The Ethics of Caring for People You Know Personally Episode 187: The Critical Need for Well-Being and Resiliency and How to Practice Episode 91: The Seasons of Survivorship ONS Voice articles: Being a Patient Taught Me How to Be a Better Oncology Nurse by Margaret Hopkins Sharing Our Stories Supports, Celebrates, and Advances the Nursing Profession Our Unified Voices Can Improve Cancer Survivorship Care Why I Truly Understand How Our Patients Hold Onto Hope ONS book: Oncology Nurse Navigation: Delivering Patient-Centered Care Across the Continuum (third edition) ONS course: Essentials in Survivorship Care for the Advanced Practice Provider ONS Nurse Well-Being Learning Library ONS Huddle Cards: Coping Moral Resilience Survivorship Care Connie Henke Yarbro Oncology Nursing History Center To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode Parsons: "I thought I knew cancer. I thought I knew the treatment. I thought I knew the side effects. There's so much I didn't know. There's so much behind the scenes before a patient comes and sits in my chair. The stuff that they go through I now can understand. It surprised me how much I didn't know." TS 11:39 Hopkins: "I had been thinking I'm going to be that hero, that I can go to work. I work at night, get 8 am radiation appointments, and go home and go to sleep and wake up and go to work again because everyone said, 'Oh, it's not that bad. Radiation will be okay. You can work.' … But the real challenge for me was I didn't know how to be a patient and a nurse at the same time. And my first radiation treatment, I go in there, and I change into the gown, and then I started cleaning up because I was getting treatment done at the hospital where I worked, and were taught if you see a mess, you clean it. So I was acting like a nurse. And I almost wanted to go help the other patients, but I couldn't because I had to focus on healing." TS 15:36 Dickerson: "What made the difference for me were the nurses who didn't just treat my illness. They treated me as a whole person—my emotions, my feelings. They made me smile. They would hold my hand or just take a moment to really ask, 'Hey, how are you?' And those small, little gestures made me feel worthy, made me feel like a human. I always tell nurses it's not just about the chemo; it's about the connection. Sometimes your presence is the most healing thing that you can offer to your patient." TS 30:52

This week, hosts Tom Rivett Carnac and Paul Dickenson delve into the rapidly emerging - and faintly surreal - world of solar geoengineering. Politico journalist Karl Mathiesen joins us to unpack his investigation into Stardust, a VC-backed startup claiming it's ready to spray particles into the stratosphere. Karl explains why this technology is suddenly attracting serious money, why scientists still have major questions about safety and side effects, and how in some places, the global regulatory landscape is almost nonexistent.And from technological disruption to political stability, former New Zealand Prime Minister Jacinda Ardern, reflects on the leadership we need. She's unflinchingly honest about why so many politicians still choose “fear and blame” over long-term action, and why climate remains New Zealand's “nuclear-free moment.” A test of political character as much as policy. Her argument is hopeful: people, she insists, are ahead of their politics.As we march towards the end of 2025, these conversations map the terrain of 2026: technologies racing ahead, governance lagging behind, and a public increasingly hungry for leaders willing to act with integrity. If you want to understand where the climate fight is really heading this episode is essential.Learn more:

Send us a textSunday, Nov. 23, 2025, message from apostle Tommy Miller, senior pastor at Legacy Church, New Philadelphia, Ohio. Part 4 in our series titled From Spirit to Stardust"The first thing that the gospel offers salvation from is human lineage. The human experience formed by Adam's separation and delusion. ... If you're saved from being a human, you are saved into the triune God in His perichoresis, His circle dance."Full Sunday service, including worship, offering and announcements, can be found in our Live section.Get more life-changing content from the co-founding pastor at Legacy Church: https://linktr.ee/tommymillerLearn more about Legacy Church: https://www.legacychurchint.org/Follow us on Facebook: https://www.facebook.com/legacychurchohFollow us on YouTube: http://www.youtube.com/@legacychurchohSow into what we're doing: GIVE - LEGACY CHURCH#asheissoareweinthisworld #asheissoareweinthisworld #unveiled #conscience #sons #manifestsons #union #legacychurchoh #newcreation #jesus #church #jesuschrist #gospel #transfigured #revelator #apostle #deathless #immortality #believe #bible #creator #godisgood #grace #hope #sermonshots #sermonclips #holyspirit #love #godislove #kingdom #peace #freedom #facebook #memes #truth #inspiration #motivationalquotes #vibes #positivevib Support the show

Send us a textThe Sunday, Nov. 30, 2025, message is Part 5 in the series called From Spirit to Stardust. Apostle Tommy Miller examines Jesus's interactions with the rich young ruler, the woman with the issue of blood, the widow of Nain, the demon-possessed man, and lepers to demonstrate that salvation is about God rescuing people from current suffering, isolation, and oppression. Excerpt: "The incarnation of the God-Man reoriented you and I to heaven's reality. And when we put faith in the appearing of our Lord and Savior Jesus Christ, He abolishes death and He brings to light life and immortality through the gospel. And in His incarnation, He gives us witness to what that salvific experience provides for us."Get more life-changing content from the co-founding pastor at Legacy Church: https://linktr.ee/tommymillerLearn more about Legacy Church: https://www.legacychurchint.org/Follow us on Facebook: https://www.facebook.com/legacychurchohFollow us on YouTube: http://www.youtube.com/@legacychurchohSow into what we're doing: GIVE - LEGACY CHURCH #asheissoareweinthisworld #asheissoareweinthisworld #unveiled #conscience #sons #manifestsons #union #legacychurchoh #newcreation #jesus #church #jesuschrist #gospel #transfigured #revelator #apostle #deathless #immortality #believe #bible #creator #godisgood #grace #hope #sermonshots #sermonclips #holyspirit #love #godislove #kingdom #peace #freedom #facebook #memes #truth #inspiration #motivationalquotes #vibes #positivevibes #christ #jesuslovesyou #russellbrand #jordanbpeterson #joerogan #atm #tommymiller #soulintelligence #EQ #emotionalintelligence Support the show

The Rhapsody crew and their new friend, Ko, pursue a lead...   You do NOT need to listen to Overture to enjoy Anthem! If you have the appetite to listen to both, we recommend starting with Anthem, then going back to listen to Overture!   Gain access to an exclusive campaign, Shroud Over Saltmarsh, over on Patreon: https://legendsofavantris.com/patreon The Crooked Moon, a folk horror supplement for 5e, is available for preorder! Get the Crooked Moon at: https://thecrookedmoon.com/ Watch more D&D adventures in the world of Avantris live on Twitch: https://www.twitch.tv/legendsofavantris Check out our merch store: https://shop.legendsofavantris.com  Join our community on Discord: https://legendsofavantris.com/discord Watch our many campaigns on YouTube: https://legendsofavantris.com/youtube  All other links: https://linktr.ee/legendsofavantris   Watch the full episode here: https://youtu.be/LdmZ17y11MY?si=h-HWL737dDx6HcGO

Autumn is here on the Talking Heads podcast - as the last vestiges of Summer in the garden dodge the wet and windy weather while trying to give the last hurrah before that inevitable but pleasantly seasonable slide into the hibernation of winter. But gardeners never sleep so Lucy and Saul are still out and about in their plots plying the horticultural trade they both love. So join them both for more horti-waffle and insights into the life of the modern, professional gardener.Leaves, frost and rain...that's been this Autumn summed up...so not much gardening talk on todays podcast but instead two pieces of huge news in Saul and Lucy's lives. After 10 years of early mornings, tractor breakdowns and the occasional piece of cake Saul is leaving Stonelands to take up a new job role at Plant Heritage, while Lucy becomes a two-time winner of the Garden Media Guilds Practical Journalist of the Year! You would have thought the pair were good at their jobs...well lets find out..Instagram link:Lucy lucychamberlaingardensLinkedIn link:Saul WalkerIntro and Outro music from https://filmmusic.io"Fireflies and Stardust" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Support the show

Following in the footsteps of The Princess Bride, this star-studded Romantic Fantasy is narrated by Ian McKellen and is a wonderful tale of a small countryside town that borders a magical land. A young man must venture into the magical world to retrieve a fallen star.

"Antibody–drug conjugates (ADCs) have three basic parts: the antibody part, the cytotoxic chemo, and the linker that connects the two. First, the antibody part binds to the target on the surface of the cell. Antibodies can be designed to bind to proteins with a very high level of specificity. That's what gives it the targeted portion. Then the whole thing gets taken up by the cell and broken down, which releases the chemotherapy part. Some sources will call this the 'payload' or the 'warhead.'  That's the part that's attached to the 'heat-seeking' part, and that's what causes the cell death," Kenneth Tham, PharmD, BCOP, clinical pharmacist in general oncology at the University of Washington Medicine and Fred Hutchinson Cancer Center in Seattle, WA, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about antibody–drug conjugates. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by November 28, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to the mechanism of action of antibody–drug conjugates. Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Pharmacology 101 series Episode 303: Cancer Symptom Management Basics: Ocular Toxicities Episode 283: Desensitization Strategies to Reintroduce Treatment After an Infusion-Related Reaction ONS Voice articles: An Oncology Nurse's Guide to Cancer-Related Ocular Toxicities Antibody–Drug Conjugates Join the Best of Two Worlds Into One New Treatment Nursing Management of Adverse Events From Enfortumab Vedotin Therapy for Urothelial Cancer Oncology Nurses' Role in Translating Biomarker Testing Results The Pharmacist's Role in Combination Cancer Treatments ONS Voice drug reference sheets: Belantamab mafodotin-blmf Datopotamab deruxtecan-dlnk Enfortumab vedotin Fam-trastuzumab deruxtecan-nxki ONS book: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) ONS course: ONS Fundamentals of Chemotherapy and Immunotherapy Administration™ Clinical Journal of Oncology Nursing articles: Antibody–Drug Conjugates and Ocular Toxicity: Nursing, Patient, and Organizational Implications for Care Nurse-Led Grading of Antineoplastic Infusion-Related Reactions: A Call to Action Other ONS resources: Antineoplastic Administration Huddle Card Biomarker Database Chemotherapy Huddle Card Monoclonal Antibodies Huddle Card Association of Cancer Care Centers (ACCC) antibody–drug conjugates page Drugs@FDA Hematology/Oncology Pharmacy Association (HOPA) National Cancer Institute cancer drugs page Network for Collaborative Oncology Development and Advancement (NCODA) clinical resource library ACCC/HOPA/NCODA/ONS Patient Education Sheets website To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org Highlights From This Episode "The mechanism of action of the chemo itself depends on what agent or what 'warhead' is attached. Generally, [ADCs] have some kind of cytotoxic mechanism related to many of the chemotherapies that we use in practice, without attachment to the antibody. Some of them can be microtubule inhibitors, vinca alkaloids like vincristine. Some of them can be topoisomerase I (TOP1) inhibitors like irinotecan. Some can be alkylating agents that cause DNA breaks. So, again, looking back at the arsenal we have of cytotoxic chemo, these can all be incorporated into the ADCs." TS 5:54 "I want to talk about a case where the biomarker is being tested, but the biomarker isn't the target that you're looking for. One good case of this is a newer agent that was approved called datopotamab deruxtecan. The datopotamab portion is specific to a target called 'trophoblast cell surface antigen 2' (TROP2), which is expressed on the surface of many epithelial cancers. This agent was first approved in hormone receptor-positive, HER2-negative breast cancer, and received accelerated approval in patients with non-small cell lung cancer (NSCLC) with an EGFR mutation. ... The antibody looks for a target, TROP2. But in both of these cases—in the breast cancer and the NSCLC—you're testing for expression of different mutations or lack thereof. You're not looking for expression of TROP2. There's more research that needs to be done about the relationship between TROP2 expression and the presence or absence of these other biomarkers, but until we know more, we're actually testing for biomarkers that aren't the target of the ADC." TS 10:22 "There are common adverse advents to antibodies and chemo in general. Because we have both of these components, we want to watch out for the adverse effects of both of them. Antibodies, as with most proteins, can trigger an immune response or an infusion reaction. So, many ADCs can also cause hypersensitivity or infusion reactions. The rates of that are really variable and depend on the actual antibodies themselves. Then you have the cytotoxic component, the chemotherapy component, which has its own characteristic side effects. So, if we think of general chemo side effects—fatigue, nausea, bone marrow suppression, alopecia—these can [occur] with a lot of ADCs as well." TS 15:34 "The rate of ocular toxicity in [mirvetuximab soravtansine] is quite high. The manufacturer reports that this can occur in up to 60% of patients. With rates so high, the manufacturer recommends a preventive strategy. For this particular agent, [they] recommend patients have required eyecare. ... This ocular toxicity is something we do see in other ADCs that don't have the same target and don't necessarily have the same payload component. For example, tisotumab vedotin and again, datopotamab deruxtecan, can both cause ocular toxicities and both would have required ocular supportive care." TS 20:08 "Overall, I feel like the future is incredibly bright for these agents. There have only been around a dozen therapies approved by the U.S. Food and Drug Administration (FDA) despite this idea—the first agent came out in 2000. So, 25 years later, there are only around a dozen FDA-approved treatments. But there are so many more that are coming through the pipeline. And as we're discovering more biomarkers and developing more specialized antibodies, it's only natural that more ADCs will follow." TS 26:50

Songs include: Stardust by Artie Shaw, Swinging On a Star by Bing Crosby, The Second Star to the Right by Doris Day, Stars Fell on Alabama by Guy Lombardo and The Stars and Stripes Forever by Frankie Laine.

Autumn is here on the Talking Heads podcast - as the last vestiges of Summer in the garden dodge the wet and windy weather while trying to give the last hurrah before that inevitable but pleasantly seasonable slide into the hibernation of winter. But gardeners never sleep so Lucy and Saul are still out and about in their plots plying the horticultural trade they both love. So join them both for more horti-waffle and insights into the life of the modern, professional gardener.Balancing clients, weather, school runs and shifting workloads is all part and parcel of the professional gardener's lifestyle, so Lucy lets us listen in on her teabreaks this week to reveal exactly what her diary involves. Whether she's judging tide times on Mersea Island, dodging rainclouds in her village or dashing across town to help out her smallholder parents, there's never a dull moment and each week poses different challenges. But, of course, there's always time for a much-loved biscuit (or mince pie, or jam doughnut, or slice of lemon drizzle, or....).Instagram link:Lucy lucychamberlaingardensLinkedIn link:Saul WalkerIntro and Outro music from https://filmmusic.io"Fireflies and Stardust" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Support the show

"Any time the patient hears the word 'cancer,' they shut down a little bit, right? They may not hear everything that the oncologist or urologist, or whoever is talking to them about their treatment options, is saying. The oncology nurse is a great person to sit down with the patient and go over the information with them at a level they can understand a little bit more. To go over all the treatment options presented by the physician, and again, make sure that we understand their goals of care," ONS member Clara Beaver, DNP, RN, AOCNS®, ACNS-BC, manager of clinical education and clinical nurse specialist at Karmanos Cancer Institute in Detroit, MI, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about prostate cancer treatment considerations for nurses.  Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by November 21, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to the treatment of prostate cancer. Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Episode 387: Prostate Cancer Screening, Early Detection, and Disparities Episode 373: Biomarker Testing in Prostate Cancer Episode 324: Pharmacology 101: LHRH Antagonists and Agonists Episode 321: Pharmacology 101: CYP17 Inhibitors Episode 208: How to Have Fertility Preservation Conversations With Your Patients Episode 194: Sex Is a Component of Patient-Centered Care ONS Voice articles: Communication Models Help Nurses Confidently Address Sexual Concerns in Patients With Cancer Exercise Before ADT Treatment Reduces Rate of Side Effects Frank Conversations Enhance Sexual and Reproductive Health Support During Cancer Nurses Are Key to Patients Navigating Genitourinary Cancers Sexual Considerations for Patients With Cancer The Case of the Genomics-Guided Care for Prostate Cancer ONS books: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (Second Edition) Manual for Radiation Oncology Nursing Practice and Education (Fifth Edition) Clinical Journal of Oncology Nursing articles: Brachytherapy: Increased Use in Patients With Intermediate- and High-Risk Prostate Cancers Physical Activity: A Feasibility Study on Exercise in Men Newly Diagnosed With Prostate Cancer The Role of the Advanced Practice Provider in Bone Health Management for the Prostate Cancer Population Oncology Nursing Forum articles: An Exploratory Study of Cognitive Function and Central Adiposity in Men Receiving Androgen Deprivation Therapy for Prostate Cancer ONS Guidelines™ for Cancer Treatment–Related Hot Flashes in Women With Breast Cancer and Men With Prostate Cancer Other ONS resources: Biomarker Database (refine by prostate cancer) Biomarker Testing in Prostate Cancer: The Role of the Oncology Nurse Brachytherapy Huddle Card External Beam Radiation Huddle Card Hormone Therapy Huddle Card Luteinizing Hormone-Releasing Hormone Antagonist Huddle Card Sexuality Huddle Card American Cancer Society prostate cancer page National Comprehensive Cancer Network homepage To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org Highlights From This Episode "I think it's important to note that urologists are usually the ones that are doing the diagnosis of prostate cancer and really start that staging of prostate cancer. And the medical oncologists usually are not consulted until the patient is at a greater stage of prostate cancer. I find that it's important to state because a lot of our patients start with urologists, and by the time they've come to us, they're a lot further staged. But once a prostate cancer has been suspected, the patient needs to be staged for the extent of disease prior to that physician making any treatment recommendations. The staging includes doing a core biopsy of the prostate gland. During this core biopsy, they take multiple different cores at different areas throughout the prostate to really look to see what the cancer looks like." TS 1:46 "[For] the very low- and low-risk group, the most common [treatment] is active surveillance. ... Patients can be offered other options such as radiation therapy or surgery if they're not happy with active surveillance. ... The intermediate-risk group has favorable and unfavorable [status]. So, if they're a favorable, their Gleason score is usually a bit lower, things are not as advanced. These patients are offered active surveillance and then either radical prostatectomy with possible removal of lymph nodes or radiation—external beam or brachytherapy. If a patient has unfavorable intermediate risk, they are offered radical prostatectomy with removal of lymph nodes, external radiation therapy plus hormone therapy, or external radiation with brachytherapy. All three of these are offered to patients, although most frequently we see that our patients are taken in for radical prostatectomy. For the high- or very high-risk [group], patients are offered radiation therapy with hormone therapy, typically for one to three years. And then radical prostatectomy with removal of lymph nodes could also be offered for those patients." TS 7:55 "Radiation can play a role in any risk group depending on the patient's preference. ... The types of radiation that we use are external beam, brachytherapy, which is an internal therapy, and radiopharmaceuticals, [which are] more for advanced cancer, but we are seeing them used in prostate [cancer] as well. External beam radiation focuses on the tumor and any metastasis we may have with the tumor. It can be used in any risk [group] and for recurrence if radiation has not been done previously. If a patient has already been radiated to the pelvic area or to the prostate, radiation is usually not given again because we don't want to damage the patient any further. Brachytherapy is when we put radioactive pellets directly into the prostate. For early-stage prostate cancer, this can be given alone. And for patients who have a higher risk of the cancer growing outside the prostate, it can be given in combination with external beam radiation. It's important to note with brachytherapy, it cannot be used on patients who've had a transurethral resection of the prostate or any urinary problems. And if the patient has a large prostate, they may have to be on some hormone therapy prior to brachytherapy, just to shrink that prostate down a little bit to get the best effect. ... Radiopharmaceuticals treat the prostate-specific membrane antigen." TS 11:05 "The side effects of surgery are usually what deter the patient from wanting surgery. The first one is urinary incontinence. A lot of times, a patient has a lot of urinary incontinence after they have surgery. The other one is erectile dysfunction. A lot of patients may not want to have erectile dysfunction. Or, if having an erection is important to the patient, they may not want to have surgery to damage that. In this day and age, physicians have gotten a lot better at doing nerve-sparing surgeries. And so they really do try to do that so that the patient does not have any issues with erectile dysfunction after surgery. But [depending on] the extent of the cancer where it's growing around those nerves or there are other things going on, they may not be able to save those nerves." TS 15:26 "Luteinizing hormone-releasing hormone, or LHRH antagonists or analogs, lower the amount of testosterone made by the testicles. We're trying to stop those hormones from growing to prevent the cancer. ... When we lower the testosterone very quickly, there can be a lot more side effects. But if we lower it a little bit less, we can maybe help prevent some of them. The side effects are important. When I was writing this up, I was thinking, 'Okay, this is basically what women go through when they go through menopause.' We're decreasing the estrogen. We're now decreasing the testosterone. So, the patients can have reduced or absent sexual desire, they can have gynecomastia, hot flashes, osteopenia, anemia, decreased mental sharpness, loss of muscle mass, weight gain, and fatigue." TS 17:50 "What we all need to remember is that no patient is the same. They may not have the same goals for treatment as the physicians or the nurses want for the patient. We talked about surgery as the most common treatment modality that's presented to patients, but it's not necessarily the option that they want. It's really important for healthcare professionals to understand their biases before talking to the patients and the family. It's also important to remember that not all patients are in heterosexual relationships, so we need to explain recovery after treatment to meet the needs of our patients and their sexual relationships, which is sometimes hard for us. But remembering that—especially gay men—they may not have the same recovery period as a heterosexual male when it comes to sexual relationships. So, making sure that we have those frank conversations with our patients and really check our biases prior to going in and talking with them." TS 27:16

Today's Song of the Day is “Copycats” by hip-hop artist Danny Brown, featuring underscores. The song comes from Brown's new album, Stardust, which released November 7 on Warp Records.

20251114- Lew Rice (125th St. BID), Scott Barbarino (Ellen's Stardust), Linda Perillo (Italy Unfiltered '26) by That KEVIN Show

"It's critical to identify those mutations found that are driving the cancer's growth and guide the personalized treatment based on those results. And important to remember, too, early testing is crucial for patients with non-small cell lung cancer (NSCLC). In studies, it has been found to be associated with improved survival outcomes and reduced mortality," ONS member Vicki Doctor, MS, BSN, BSW, RN, OCN®, precision medicine director at the City of Hope Atlanta, GA, Chicago, IL, and Phoenix, AZ, locations, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about the oncology nurse's role in NSCLC biomarker testing. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  This podcast is sponsored by Lilly Oncology and is not eligible for NCPD contact hours. ONS is solely responsible for the criteria, objectives, content, quality, and scientific integrity of its programs and publications. Episode Notes  This episode is not eligible for NCPD. ONS Podcast™ episodes: Episode 363: Lung Cancer Treatment Considerations for Nurses Episode 359: Lung Cancer Screening, Early Detection, and Disparities Episode 238: Cancer Genomics for Every Oncology Nurse Episode 157: Biomarker Testing Improves Outcomes for Patients With Non-Small Cell Lung Cancer ONS Voice articles: Non-Small Cell Lung Cancer Prevention, Screening, Diagnosis, Treatment, Side Effects, and Survivorship Only a Third of Patients With Advanced Cancer Get Biomarker Testing, Limiting Use of Potentially Effective Precision Therapies Precision Medicine in Lung Cancer: How Comprehensive Testing Optimizes Patient Outcomes Targeted Therapies Are Transforming the Treatment of Non-Small Cell Lung Cancer ONS book: Guide to Cancer Immunotherapy (second edition) ONS course: Genomic Foundations for Precision Oncology Clinical Journal of Oncology Nursing article: Using Nurse Navigators to Improve Timeliness of Biomarker Testing for Non-Small Cell Lung Cancer Oncology Nursing Forum article: Precision Medicine Testing and Disparities in Health Care for Individuals With Non-Small Cell Lung Cancer: A Narrative Review Other ONS resources: Best Practices for Biomarker Testing in Non-Small Cell Lung Cancer: A Case Study Genomics and Precision Oncology Learning Library Genomics Case Study: Precision Medicine in the Setting of Metastatic Non-Small Cell Lung Cancer Biomarker Database (refine by non-small cell lung cancer) Genomic Biomarkers Huddle Card Targeted Therapy Huddle Card National Comprehensive Cancer Network homepage To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org Highlights From This Episode "These biomarkers are used to provide information about cancer's characteristics or behavior. In oncology precision medicine specifically, molecular tests can help with diagnosing a cancer that is maybe an unknown primary. It can help with monitoring response to therapy, detect recurrence of disease before other tests can find that, predict prognosis or how aggressive the cancer may be, and guide treatment decisions for targeted therapies." TS 3:14 "Some of the key biomarkers recommended by the National Comprehensive Cancer Network (NCCN) to be tested in patients who have NSCLC are EGFR, ALK, KRAS, BRAF, MET exon 14 skipping mutation, HER2 which is a protein expression from an ErbB protein, PD-L1 which is a protein expression that's used to guide immunotherapy choices, and then finally there are three fusions: ROS1, RET, and NTRK. [These] are pretty rare but really important to be tested for in patients who have NSCLC." TS 3:46 "Another important challenge for nurses related to this topic is that these results may not reveal a targeted mutation for the patient and that could be very disappointing. So, being able to provide that emotional support to a patient if they have that result … you can actually reinforce with them that if [they] go onto another treatment that the physician decides to put [them] on, the tumor can change. New pathogenic variants can develop based on the treatment that they're getting, and another test can be done. And maybe at that time—a new biomarker that could be targeted—we'd be seeing on the new test." TS 7:32  "Another circumstance we didn't talk about yet is that maybe the result came back saying that the quality was not sufficient. And sometimes that happens, but that doesn't mean that we're at the end of the road, necessarily. So, you could explain to the patient that that may mean that possibly, a new biopsy would be ordered by the physician. Or if a new biopsy or another tissue sample is not available, then maybe the physician would pivot to sending a blood specimen for the molecular testing. So that would definitely be a way [nurses] could support their patients." TS 11:52 "In the case of patients with NSCLC, early testing is so important. So, advocating for that prompt biomarker testing to be done, making sure that it's comprehensive, that it's actually looking for all of those—I think it was 12 biomarkers—that I mentioned earlier. That this testing is done as soon as possible after diagnosis or progression. Something that I talk about all the time—personalized care, precision medicine—really matters. So, tailoring treatments for patients based on the biology of the tumor that's driving the cancer's growth is really crucial if you're going to be working as an oncology nurse. Another crucial thing, because it's changing so quickly, is to stay informed." TS 16:23

Pyke gets a call from a friend with a lead...   You do NOT need to listen to Overture to enjoy Anthem! If you have the appetite to listen to both, we recommend starting with Anthem, then going back to listen to Overture!   Gain access to an exclusive campaign, Shroud Over Saltmarsh, over on Patreon: https://legendsofavantris.com/patreon The Crooked Moon, a folk horror supplement for 5e, is available for preorder! Get the Crooked Moon at: https://thecrookedmoon.com/ Watch more D&D adventures in the world of Avantris live on Twitch: https://www.twitch.tv/legendsofavantris Check out our merch store: https://shop.legendsofavantris.com  Join our community on Discord: https://legendsofavantris.com/discord Watch our many campaigns on YouTube: https://legendsofavantris.com/youtube  All other links: https://linktr.ee/legendsofavantris   Watch the full episode here: https://youtu.be/LdmZ17y11MY?si=h-HWL737dDx6HcGO

In the second half of How To!'s wide-ranging conversation about home improvement, gender, sexuality, and much more, journalist Sam Sanders and author Mercury Stardust (aka The Trans Handy Ma'am) talk with co-host Carvell Wallace about a truly daunting idea: skipping the contractors—and doing the work yourself. This episode is available to Slate Plus members now. Non-members will be able to listen on Nov. 11, 2025. If you missed the first half of this conversation, check out How To Talk to Contractors (With Sam Sanders and Mercury Stardust). Mercury's latest book is Safe and Sound: A Renter-Friendly Guide to Home Repair. And, check out the latest episodes of The Sam Sanders Show. Do you have a problem that needs solving? Send us a note at howto@slate.com or leave us a voicemail at 646-495-4001 and we might have you on the show. Subscribe for free on Apple, Spotify or wherever you listen. The show is produced by Rosemary Belson and Sophie Summergrad. Our technical director is Merritt Jacob and our supervising producer is Joel Meyer. Get more of How To! with Slate Plus! Join for exclusive bonus episodes of How To! and ad-free listening on all your favorite Slate podcasts. Subscribe from the How To! show page on Apple Podcasts or Spotify. Or, visit slate.com/howtoplus for access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

In the second half of How To!'s wide-ranging conversation about home improvement, gender, sexuality, and much more, journalist Sam Sanders and author Mercury Stardust (aka The Trans Handy Ma'am) talk with co-host Carvell Wallace about a truly daunting idea: skipping the contractors—and doing the work yourself. This episode is available to Slate Plus members now. Non-members will be able to listen on Nov. 11, 2025. If you missed the first half of this conversation, check out How To Talk to Contractors (With Sam Sanders and Mercury Stardust). Mercury's latest book is Safe and Sound: A Renter-Friendly Guide to Home Repair. And, check out the latest episodes of The Sam Sanders Show. Do you have a problem that needs solving? Send us a note at howto@slate.com or leave us a voicemail at 646-495-4001 and we might have you on the show. Subscribe for free on Apple, Spotify or wherever you listen. The show is produced by Rosemary Belson and Sophie Summergrad. Our technical director is Merritt Jacob and our supervising producer is Joel Meyer. Get more of How To! with Slate Plus! Join for exclusive bonus episodes of How To! and ad-free listening on all your favorite Slate podcasts. Subscribe from the How To! show page on Apple Podcasts or Spotify. Or, visit slate.com/howtoplus for access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

In the second half of How To!'s wide-ranging conversation about home improvement, gender, sexuality, and much more, journalist Sam Sanders and author Mercury Stardust (aka The Trans Handy Ma'am) talk with co-host Carvell Wallace about a truly daunting idea: skipping the contractors—and doing the work yourself. This episode is available to Slate Plus members now. Non-members will be able to listen on Nov. 11, 2025. If you missed the first half of this conversation, check out How To Talk to Contractors (With Sam Sanders and Mercury Stardust). Mercury's latest book is Safe and Sound: A Renter-Friendly Guide to Home Repair. And, check out the latest episodes of The Sam Sanders Show. Do you have a problem that needs solving? Send us a note at howto@slate.com or leave us a voicemail at 646-495-4001 and we might have you on the show. Subscribe for free on Apple, Spotify or wherever you listen. The show is produced by Rosemary Belson and Sophie Summergrad. Our technical director is Merritt Jacob and our supervising producer is Joel Meyer. Get more of How To! with Slate Plus! Join for exclusive bonus episodes of How To! and ad-free listening on all your favorite Slate podcasts. Subscribe from the How To! show page on Apple Podcasts or Spotify. Or, visit slate.com/howtoplus for access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

In the second half of How To!'s wide-ranging conversation about home improvement, gender, sexuality, and much more, journalist Sam Sanders and author Mercury Stardust (aka The Trans Handy Ma'am) talk with co-host Carvell Wallace about a truly daunting idea: skipping the contractors—and doing the work yourself. This episode is available to Slate Plus members now. Non-members will be able to listen on Nov. 11, 2025. If you missed the first half of this conversation, check out How To Talk to Contractors (With Sam Sanders and Mercury Stardust). Mercury's latest book is Safe and Sound: A Renter-Friendly Guide to Home Repair. And, check out the latest episodes of The Sam Sanders Show. Do you have a problem that needs solving? Send us a note at howto@slate.com or leave us a voicemail at 646-495-4001 and we might have you on the show. Subscribe for free on Apple, Spotify or wherever you listen. The show is produced by Rosemary Belson and Sophie Summergrad. Our technical director is Merritt Jacob and our supervising producer is Joel Meyer. Get more of How To! with Slate Plus! Join for exclusive bonus episodes of How To! and ad-free listening on all your favorite Slate podcasts. Subscribe from the How To! show page on Apple Podcasts or Spotify. Or, visit slate.com/howtoplus for access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Send us a textThis week,Former host Casual Coops makes his long-awaited return to join PoGoMiloUK, Ian Waterfall and Masterful 27 for a jam-packed, laughter-filled show!The boys kick things off with some stinky fun — breaking down the GMax Garbodor Max Battle Day and sharing their experiences, best (and worst) raid luck. Then it's time for the Road to Level 80, where Coops dives into his Pokémon GO grind, XP strategy, and how his playstyle has changed (or not) since leaving the podcast. Expect the usual bit of chaos!In The News, the gang explores new info from the GO Wild Area 2025 announcement — including the shiny debut of Unown K in Nagasaki and the Global Special Research featuring Dark vs Fairy medals that boost Stardust and XL Candy rewards.Coops then hosts a special edition of fan-favourite game Chasing The Tail, before discussion turns to Pikipek Community Day, the Halloween event part 2, and some truly cursed shiny luck in #ShiniesOfTheWeek.We'd like to say a massive thank you to all of our Patrons for your support, with credited Patrons from featured tiers below:#GOLDJB, Kerry & Zachary, Barside2, Mandy Croft, Mr Mossom, Mufti, DeanDHL, Masterlaxus42 & DamonMac08.#SILVERKLXVI, Dell Hazard, Spindiana, Lori Beck, Steve In Norway, CeeCeeismad, Macfloof, Saul Haberfield, Lizzie George, Sander Van Den Dreiesche, Neonnet, Ellen Rushton, James Alexander, Northern Soph, Tom Cattle, Charley Todd, Robert Wilson, MissSummerOf69, Malcolm Grinter, Jordi Castel, Thehotweasel, shinyikeamom, TonyOfPride, Joohno & Malcolm Burgess.The Gaming BlenderWe mash genres. We pitch games. You question our sanity.Listen on: Apple Podcasts SpotifySupport the showFind us on Niantic Campfire: CLICK MESend us a voice message on WhatsApp: +44 7592695696Email us: contact@incensedpodcast.comIf you'd like to buy merch, you can find us by clicking HERE for U.K. store, HERE for U.S. Oceana store or copy this link: https://incensedpodcast.myspreadshop.net/ for U.K. store or this link: https://incensed-podcast.myspreadshop.com/ for U.S. Oceana store!Hosted By: PoGoMiloUK, Ian Waterfall & Masterful 27. Produced & Edited By: Ian Waterfall & PoGoMiloUK. Administrators: HermesNinja & IAMP1RU5.Pokémon is Copyright Gamefreak, Nintendo and The Pokémon Company 2001-2016All names owned and trademarked by Nintendo, Niantic, The Pokémon Company, and Gamefreak are property of their respective owners.

SPONSORS: - Sign up for a $1 per month trial period at https://shopify.com/dannyb - Our listeners get 10% off their first month at https://betterhelp.com/dannybrown Danny Brown is locked in this week—he can't stop playing NBA 2K, he's linking up with JuiceLand to make his own smoothie, and he's got plenty to say about the “depressed generation,” performative masculinity, and staying mentally strong. Danny talks about the excitement of dropping his new album, shares his thoughts on chasing AI money, and even offers to teach you how to rap. It's classic Danny: chaotic, funny, and full of unexpected wisdom. Don't sleep—Danny's new album Stardust is out now on all platforms.

"I think we really need to push more of our oncology nurses to get into elected and appointed positions. So often we're looking at health positions to get involved in, and those are wonderful. We need nurses as secretaries of health, but there are others. We as nurses understand higher education. We understand environment. We understand energy. So I think we look broadly at, what are positions we can get in? Let's have more nurses run for state legislative offices, for our House of Representatives, for the U.S. Senate," ONS member Barbara Damron, PhD, LHD, RN, FAAN, told Ryne Wilson, DNP, RN, OCN®, CNE, ONS member and member of the ONS 50th anniversary committee, during a conversation about the future of oncology nursing advocacy and health policy. Wilson spoke with Damron and ONS member Janice Phillips, PhD, RN, CENP, FADLN, FAAN, about how ONS has advanced advocacy and policy efforts over the past 50 years and its approaches for the future. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Episode Notes  This episode is not eligible for NCPD.  ONS Podcast™ episodes: ONS 50th anniversary series Episode 229: How Advocacy Can Shape Your Nursing Career ONS Voice articles: Oncology Nurses Take to Capitol Hill to Advocate for Cancer Care Priorities Our Unified Voices Can Improve Cancer Survivorship Care With Voices Amplified by ONS, Oncology Nurses Speak Out for Patients and the Profession on Capitol Hill NOBC Partnerships Advance Nurses' Placements on Local and National Boards Nursing Leadership Has Space for You and Your Goals ONS courses: Advocacy 101: Making a Difference Board Leadership: Nurses in Governance Oncology Nursing Forum articles: Nurses on Boards: My Experience on the Moonshot Strengthening Oncology Nursing by Using Research to Inform Politics and Policy ONS Center for Advocacy and Health Policy Current ONS position statements Connie Henke Yarbro Oncology Nursing History Center Campaign for Tobacco-Free Kids Cancer Moonshot National Cancer Policy Forum National Council of State Boards of Nursing APRN Roundtable National Patient Advocate Foundation Nurses on Boards Coalition One Voice Against Cancer Patient Quality of Life Coalition Robert Wood Johnson Foundation Health Policy Fellows To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode Phillips: "I think that there are so many pressing issues, but I'm going to start with any kind of threats or legislation that's poised to take away safety-net resources. It's really going to set us back because we all know that, particularly for minorities and certain other underserved populations, they have experienced poor cancer outcomes for a variety of reasons, variety of socioeconomic reasons, lack of access to quality screening resources—you name it. When you take away those safety net resources and take away resources for people who are already underserved, uninsured, or underinsured, it also jeopardizes their ability to get proper screening, get proper follow-up, have access to state of the art cancer services. I think the lack of affordability of health care is a problem that continues to challenge us, whether you on Medicaid or whether you have limited insurance." TS 10:16 Damron: "Because ONS is so grounded in science and research—we're not just a clinical organization; we're grounded in scholarship, science, research, and publication—we're able to take this vast network of strong clinicians [and combine it] with amazing scientists. … We've had some amazing scientists come out of ONS; some of the leading nurse scientists of all time were also oncology nurses. So by combining this, we're able to make a difference at the state and federal level. So the advocacy work that I've been involved in, state and federal levels, really involved working with the ONS staff involved with advocacy and those scientists and clinicians who brought that expertise." TS 18:19 Phillips: "I think expanding the work around multiculturalism in oncology will always be important. Are there any new partnerships or avenues that ONS can reach out to or explore? Maybe there are other specialty organizations or groups—and not always necessarily nursing— because as we think about the determinants of health, we think about things like health and all policies. Maybe there are other disciplines or other specialties that we need to embrace as we launch our agendas." TS 23:28 Damron: "As nurses, just our basic nursing training, we get these skills—we see a problem, we identify the problem, we assess what we're going to do about it, we do it, and then we evaluate what we did. Does that work or not? That's how you make policy. So we were all trained in this. Then what you bring on top of that are oncology nursing experience, whether it's clinical, whether it's research, whether it's teaching, practice, etc. Those continue to refine those skills that are basic to us as nurses. We have this built-in skill set, and we need to own it and understand it." TS 30:25

Sam Sanders is many things: journalist, podcaster, pop-culture obsessive, and a familiar voice from public radio. He's also ”quite possibly the world's most hesitant homeowner.” Sam wants to fix up the house he recently bought, but three things are holding him back: First, he doesn't have a clue where to start. Second, he's not very handy. And third, he's intimidated by the thought of talking with contractors (who might discover the first two things about him). In the first episode of a two-part series, Carvell Wallace brings on home improvement expert and bestselling author Mercury Stardust (aka The Trans Handy Ma'am) to guide Sam in conquering his fears. Mercury's latest book is Safe and Sound: A Renter-Friendly Guide to Home Repair. Check out the latest episodes of The Sam Sanders Show. Next week: How To Take Charge of Home Repair (with Sam Sanders and Mercury Stardust). Can't wait for part 2? Slate Plus members can listen to that episode in their feeds right now!  Do you have a problem that needs solving? Send us a note at howto@slate.com or leave us a voicemail at 646-495-4001 and we might have you on the show. Subscribe for free on Apple, Spotify or wherever you listen. The show is produced by Rosemary Belson and Sophie Summergrad. Our technical director is Merritt Jacob and our supervising producer is Joel Meyer. Get more of How To! with Slate Plus! Join for exclusive bonus episodes of How To! and ad-free listening on all your favorite Slate podcasts. Subscribe from the How To! show page on Apple Podcasts or Spotify. Or, visit slate.com/howtoplus for access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Sam Sanders is many things: journalist, podcaster, pop-culture obsessive, and a familiar voice from public radio. He's also ”quite possibly the world's most hesitant homeowner.” Sam wants to fix up the house he recently bought, but three things are holding him back: First, he doesn't have a clue where to start. Second, he's not very handy. And third, he's intimidated by the thought of talking with contractors (who might discover the first two things about him). In the first episode of a two-part series, Carvell Wallace brings on home improvement expert and bestselling author Mercury Stardust (aka The Trans Handy Ma'am) to guide Sam in conquering his fears. Mercury's latest book is Safe and Sound: A Renter-Friendly Guide to Home Repair. Check out the latest episodes of The Sam Sanders Show. Next week: How To Take Charge of Home Repair (with Sam Sanders and Mercury Stardust). Can't wait for part 2? Slate Plus members can listen to that episode in their feeds right now!  Do you have a problem that needs solving? Send us a note at howto@slate.com or leave us a voicemail at 646-495-4001 and we might have you on the show. Subscribe for free on Apple, Spotify or wherever you listen. The show is produced by Rosemary Belson and Sophie Summergrad. Our technical director is Merritt Jacob and our supervising producer is Joel Meyer. Get more of How To! with Slate Plus! Join for exclusive bonus episodes of How To! and ad-free listening on all your favorite Slate podcasts. Subscribe from the How To! show page on Apple Podcasts or Spotify. Or, visit slate.com/howtoplus for access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Sam Sanders is many things: journalist, podcaster, pop-culture obsessive, and a familiar voice from public radio. He's also ”quite possibly the world's most hesitant homeowner.” Sam wants to fix up the house he recently bought, but three things are holding him back: First, he doesn't have a clue where to start. Second, he's not very handy. And third, he's intimidated by the thought of talking with contractors (who might discover the first two things about him). In the first episode of a two-part series, Carvell Wallace brings on home improvement expert and bestselling author Mercury Stardust (aka The Trans Handy Ma'am) to guide Sam in conquering his fears. Mercury's latest book is Safe and Sound: A Renter-Friendly Guide to Home Repair. Check out the latest episodes of The Sam Sanders Show. Next week: How To Take Charge of Home Repair (with Sam Sanders and Mercury Stardust). Can't wait for part 2? Slate Plus members can listen to that episode in their feeds right now!  Do you have a problem that needs solving? Send us a note at howto@slate.com or leave us a voicemail at 646-495-4001 and we might have you on the show. Subscribe for free on Apple, Spotify or wherever you listen. The show is produced by Rosemary Belson and Sophie Summergrad. Our technical director is Merritt Jacob and our supervising producer is Joel Meyer. Get more of How To! with Slate Plus! Join for exclusive bonus episodes of How To! and ad-free listening on all your favorite Slate podcasts. Subscribe from the How To! show page on Apple Podcasts or Spotify. Or, visit slate.com/howtoplus for access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices