Podcasts about Stardust

"There are a huge array of medical dynamics that people endure, and when they leave a lasting impact, a word that we don't use widely enough is the word 'trauma.' There's an entire category of phenomena in the medical arena that are, in fact, traumatic. One way we know that these experiences are traumatic is that we know that huge portions of people who experience things like cancer do indeed develop problems like [post-traumatic stress disorder]," James C. Jackson, PsyD, research professor at Vanderbilt University Medical Center in Nashville, TN, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about understanding medical trauma in oncology. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by June 26, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report increased knowledge of medical trauma and its effects on patients with cancer, caregivers, and healthcare professionals. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 315: Processing Grief as an Oncology Nurse Episode 287: Tools, Techniques, and Real-World Examples for Difficult Conversations in Cancer Care Episode 276: Support Young Families During a Parent's Cancer Journey Episode 257: Redefining the Bell: The Ethics of Hope for Oncology Nurses and Patients Episode 103: What Oncology Nurses Need to Know to Support Caregivers ONS Voice articles: 'Between Two Kingdoms' Gives Us a Glimpse Into How Patients and Families Experience Malignancy AYA Cancer Survivors Experience Five Times Higher Depression Rates Than Individuals Diagnosed at Older Ages From Stigma to Support: Changing the Cancer Conversation Help Caregivers Control the Chronic Stress of Cancer Care and Manage PTSD Moral Injury and Trauma in Nursing Trauma-Informed Care Provides Person-Centered Support for Patients During Deep Distress When the Story Ends, Cancer Does Not Win: Reframing Death in Terminal Cancer Care Word Choice Matters When Caring for Patients With Cancer ONS course: ONS Psychosocial Dimensions of Cancer Care™  Clinical Journal of Oncology Nursing articles: Psychosocial Barriers to Care: Recognizing and Responding Through a Trauma-Informed Care Approach Trauma-Informed Care Addressing the Mental and Emotional Needs of Patients With Cancer Oncology Nursing Forum articles: Post-Traumatic Distress and Symptom Experience in Patients With Head and Neck Cancer–Related Tracheostomy and Family Caregivers The Effect of Neuroticism, Fear of Progression, and Self-Efficacy on Post-Traumatic Growth in Patients With Lung Cancer Undergoing Chemotherapy Reclaiming Your Life From Medical Trauma by James C. Jackson To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Many people have a notion about what medical trauma is, but perhaps they lack a definition. I use a definition that is deliberately broad because I think it is better to be inclusive than exclusive. A medical trauma to me is a medical experience or a medical encounter that basically leaves a mark. It leaves an emotional mark, and that mark is significant enough to disrupt your daily life." TS 2:06 "When somebody develops a life-threatening illness—let's say cancer—it's not their problem only. It's very much a family problem. It affects any manner of people. There is literature that says that family members of people with life-threatening conditions often have rates of PTSD that are every bit as high as the patients do. There's also literature that says that if we can identify this issue as a family problem—a family challenge, not just an individual challenge—then very often that patient is going to do better." TS 8:23 "We just need to make space for people to feel however they feel. And we need to emphasize, I think, that in some ways, even though there's no cancer on the scan, cancer casts a long shadow in the lives of people, which is why when patients after cancer see their primary care provider, when they come back for a checkup with oncology, we need to continue this conversation of 'How is your mental health? Are you okay? How's your anxiety? How are you managing?' … We need to be really curious and kind, and we need to query people about how they're doing, even if officially they don't have cancer." TS 16:20 "Trauma-informed care has become a bit of a buzzword in our culture. But when it is engaged correctly, I think it's really important. And I think in a nutshell, what it means is that as providers, we need to recognize that some situations and circumstances are likely to be traumatic, and we need to pivot and engage people differently now that we know that. Specific features of trauma-informed care might be we're really going to value your emotional safety. We're going to emphasize that. We are going to emphasize boundaries. We are going to ask your permission instead of telling you how to do things. We are going to be really attentive to the language we use to engage you because we're aware of there might be things about your situation that are really triggering." TS 28:15 "I think one [misconception] certainly is that it is only afflicting and affecting people who are frail or weak—not very strong. That's emphatically not true. But that's a popular misconception—that if I'm strong enough, if I'm resilient enough, this experience will not be traumatic to me. It's just not true. Medical trauma doesn't just happen in emotionally weak people. Medical trauma can impact people of all sorts." TS 33:42 "The other misconception, I think, is that there is no hope for people in the throes of medical trauma. I'm not advocating 'hopium,' It's a term that was coined, I think, during the pandemic. I don't think that living with medical trauma is all rainbows and unicorns and shiny things. But the truth is, if you get the treatment that you need, you can find a way to thrive with medical trauma even as you're impacted by medical trauma. This, this 'both-and-ness' is really true. You can both be adversely affected and you can even find some beauty in your struggle. Both can be true." TS 34:13 "I wish people understood that there is a name for this phenomenon. We're naming it here today medical trauma. Not everyone who has cancer has medical trauma—not even close—but there are many people who do. And I think many of those people, they don't quite have a name for it. And when I introduce this name for it—trauma—many of them say, 'Oh, my gosh, that makes so much sense. I didn't quite understand why I was struggling so much with this. I didn't quite understand why it casts such a long shadow in my life. I didn't really understand why I was having panic attacks every time I had to get another scan at the oncology office to see if my breast cancer had returned. Now I understand. Now I understand it's because it was trauma.'" TS 35:09

We're wrapping up High Fantasy month at NOTLP with the romantic Stardust, listener Gothchick's pick. Then we jibber jabber about what else we've been watching like Late Night Horror, Evil Ed, and Leviticus.  Support us on Patreon! Patrons have access to the NOTLP Discord Server, weekly virtual meetups with the hosts, ad free episodes and tons of other great content. This podcast is brought to you by the Legion of Demons at patreon.com/notlp. Our Beelzebub tier producers are: Ernest Perez Shayna Spalla Branan & Emily Intravia-Whitehead Bill Chandler Blayne Turner Monica Martinson Bill Fahrner Brian Krause Dave Siebert Joe Juvland Matt Funke "Monster Movies (with My Friends)" was written and performed by Kelley Kombrinck. It was recorded and mixed by Freddy Morris. Night of the Living Podcast Social Media:      facebook.com/notlp instagram.com/nightofthelivingpodcast youtube.com/notlpcrew https://www.tiktok.com/@nightofthelivingpodcast

Sympathische deutsche Science-Fiction-Serie in der ARD Mediathek for free: Eine junge Frau erbt ein Hotel im Weltall – mitsamt seinen skurrilen Mitarbeitern und einem großen Schuldenberg.

Fluent Fiction - Hungarian: Stardust Connections: An Astronomical Encounter in Budapest Find the full episode transcript, vocabulary words, and more:fluentfiction.com/hu/episode/2026-06-21-22-34-02-hu Story Transcript:Hu: A Budapest Tudományos Múzeum zsongott a nyári turistáktól.En: The Budapest Tudományos Múzeum buzzed with summer tourists.Hu: A hűvös, klímával ellátott termek hosszú sora kínálta magát.En: A long line of cool, air-conditioned rooms presented themselves.Hu: Az interaktív kiállítások között volt a csillagászat részlege is, ami sejtelmes, tompított fénnyel fogadta a látogatókat, hogy a galaxisok és csillagképek élénk kijelzői érvényesülhessenek.En: Among the interactive exhibitions was the astronomy section, which welcomed visitors with mysterious, dimmed lights so that the vivid displays of galaxies and constellations could shine through.Hu: Ez a rész népszerű menedékhely volt a kinti hőség elől, de leginkább a kíváncsiságot ébresztette.En: This section was a popular refuge from the outdoor heat, but most importantly, it sparked curiosity.Hu: Ákos, egy csillagászat iránt rajongó, kíváncsi, de introvertált fiatalember, csendben sétált a tárlók között.En: Ákos, a curious but introverted young man passionate about astronomy, quietly walked among the displays.Hu: Mindig is érezte a kapcsolat hiányát az emberekkel, de a csillagok világa mindig is közelebb hozta hozzá az univerzumot.En: He had always felt a lack of connection with people, but the world of stars always brought the universe closer to him.Hu: Ma is csak egy dolog járt a fejében – találni valakit, aki osztozik az ő szenvedélyében.En: Today, he had only one thing on his mind – to find someone who shares his passion.Hu: Egy színes galaxis képernyője előtt ácsorogva megpillantott egy lányt.En: Standing in front of a colorful galaxy screen, he noticed a girl.Hu: Emese ott állt, és bámulta az Androméda-galaxist.En: Emese stood there, staring at the Andromeda Galaxy.Hu: Lenyűgözte, hogyan jelenítheti meg a csillagok fényét a saját műveiben.En: She was fascinated by how she could depict the light of stars in her own works.Hu: Emese, akinek színes egyénisége és szenvedélyes természete sokfelé elkalandozott, most úgy érezte, hogy a kozmosz mégis valami különös inspirációt kínál neki.En: With a colorful personality and a passionate nature that wandered in many directions, Emese now felt that the cosmos offered her a strange inspiration.Hu: Ákos megállt, nem tudta, megszólítsa-e.En: Ákos stopped, unsure if he should speak to her.Hu: A belső bizonytalanság sokszor megakadályozta abban, hogy kezdeményezzen.En: His inner uncertainty often prevented him from making the first move.Hu: Viszont valami azt súgta neki, hogy érdemes megpróbálni.En: Yet something whispered to him that it was worth a try.Hu: Hosszan vett egy mély levegőt, és odalépett Emeséhez.En: He took a deep breath and approached Emese.Hu: "Szerinted mi a legszebb csillagkép?En: "What do you think is the most beautiful constellation?"Hu: " – kérdezte halkan, mégis reménykedve.En: he asked softly, yet hopefully.Hu: Emese kíváncsian tekintett rá: "Talán a Hattyú.En: Emese looked at him curiously: "Perhaps Hattyú.Hu: Gyönyörű és különleges.En: It's beautiful and special.Hu: És neked?En: And for you?"Hu: "Ákos szeme felcsillant: "A Fiastyúk.En: Ákos's eyes lit up: "Fiastyúk.Hu: Mindig is szerettem, hogyan ragyog az égen.En: I've always loved how it shines in the sky."Hu: "Beszélgetésük egyre mélyült, mint a csillagokkal teli galaxis.En: Their conversation deepened like a galaxy filled with stars.Hu: Észrevétlenül rátértek az Androméda-galaxisra, ráébredve, hogy mindketten mennyire vonzódnak hozzá.En: They seamlessly transitioned to the Andromeda Galaxy, realizing how both were drawn to it.Hu: Ahogy szavak mögött egy közös világ kezdett kibontakozni, egyértelművé vált, hogy valami különleges dolog alakul közöttük.En: As a shared world began to unfold behind their words, it became clear that something special was developing between them.Hu: A múzeumból kifele menet Ákos és Emese megbeszélték, hogy legközelebb a csillagok alatt folytatják találkozójukat.En: As they left the museum, Ákos and Emese agreed to continue their meeting under the stars next time.Hu: Egy budapesti obszervatóriumban akarták folytatni a beszélgetést a csillagok és a művészetek világáról.En: They wanted to carry on their conversation about the worlds of stars and arts at a Budapest observatory.Hu: Ákos úgy érezte, megtalálta azt a személyt, aki osztozik az álmaiban, Emese pedig inspirációra lelt a csillagokkal kapcsolatos megértés mélységében.En: Ákos felt he had found the person who shared his dreams, while Emese found inspiration in the depth of understanding related to stars.Hu: Most mindketten tudták, hogy az ő univerzumuk tágasabb lett.En: Now both knew that their universe had expanded.Hu: Ákos többé nem érzett távolságot másoktól, Emese pedig barátot és múzsát talált a csillagok között.En: Ákos no longer felt distant from others, and Emese had found a friend and muse among the stars.Hu: A csillagok tehát nem csak elérhetetlen pontok voltak az égen, hanem hidak is, amelyek összehozzák az embereket.En: Thus, the stars were not just unreachable points in the sky, but bridges that bring people together. Vocabulary Words:buzzed: zsongottair-conditioned: klímával ellátottpresented: kínáltainteractive: interaktívdimmed: tompítottvivid: élénkrefuge: menedékhelycuriosity: kíváncsiságintroverted: introvertáltnoticed: megpillantottdepict: megjeleníthetifascinated: lenyűgözteinner: belsőuncertainty: bizonytalanságapproached: odalépetthopefully: reménykedvecuriously: kíváncsianseamlessly: észrevétlenültransitioned: ráébredveunfold: kibontakoznispecial: különlegesobvious: egyértelművémeeting: találkozóobservatory: obszervatóriumbaninspiration: inspirációdepth: mélységébendistant: távolságotunreachable: elérhetetlenbridges: hidaktogether: összehozzák

"We typically think of the disease progressing for our higher-risk patients because many of them already start with increased blasts or a lot of dysplasia. And they have these chromosomal variants that make them prone to evolving into acute myeloid leukemia (AML). With them, we can anticipate that they are going to progress to AML. And that's what we're trying to prevent. It's kind of like a biologic evolution and not a switch," ONS member Sara Tinsley-Vance, PhD, APRN, AOCN®, nurse practitioner and quality-of-life researcher at Moffitt Cancer Center in Tampa, FL, told Lenise Taylor, MN, RN, AOCNS®, TCTCN™, oncology clinical specialist at ONS, during a conversation about long-term myelodysplastic syndrome (MDS) considerations for oncology nurses. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by June 19, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to management of long-term side effects related to myelodysplastic syndrome and its treatment. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 415: Myelodysplastic Syndrome Treatment Considerations for Oncology Nurses Episode 411: An Overview of Myelodysplastic Syndrome for Oncology Nurses Episode 256: Cancer Symptom Management Basics: Hematologic Complications Episode 220: Oncologic Emergencies 101: Febrile Neutropenia and Sepsis Clinical Journal of Oncology Nursing articles:  Exploring Experiences of Bereaved Caregivers of Older Adult Patients With Acute Myeloid Leukemia Family Caregiver Preparedness: Developing an Educational Intervention for Symptom Management Incorporating Nurse Navigation to Improve Cancer Survivorship Care Plan Delivery Oncology Nursing Forum article: An Integrative Review of Sex Differences in Quality of Life and Symptoms Among Survivors of Hematologic Malignancies ONS book: BMTCN® Certification Review Manual (second edition) ONS course: Psychosocial Dimensions of Cancer Care™  ONS Learning Libraries:  Survivorship Learning Library Hematology, Cellular Therapy, and Stem Cell Transplantation Survivorship Care Plan Huddle Card American Association of Colleges of Nursing End-of-Life Nursing Education Consortium (ELNEC) American Cancer Society: Living As a Myelodysplastic Syndrome Survivor American Society of Hematology Aplastic Anemia and MDS International Foundation: MDS Toolkit Blood Cancer United: Myelodysplastic Syndromes Family Caregiver Alliance HealthTree Foundation Inspire: MDS Support and Discussion Community Myelodysplastic Syndromes Foundation To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "When our higher-risk patients have disease-related progression, their [malignancy] can transform to AML. And we know this occurs in about one-third of our patients and is one of the most serious late effects. Even in lower-risk disease, we have this worsening marrow failure with or without increasing blast, where [patients] may have just started out with anemia, then they also develop neutropenia and thrombocytopenia. And as those counts worsen, we usually know that their disease is progressing." TS 2:47 "The golden rule is looking at the blood count but also looking at the patient and how they're doing over time. The backbone of MDS monitoring is the complete blood cell count with the differential. What you're looking for is trends over time. How many units of blood are they receiving, what threshold are you going to transfuse them at, and how many units of blood are they getting at a time? ... And then paying attention to the absolute neutrophil count for infection risk. [Another] really important piece of when you look at the differential with patients is seeing if they have any abnormal cell counts. Do they have circulating blasts? Are those monocytes going up? If you start to see blasts circulating or increasing monocytes, then their disease could be changing, even if they have low-risk disease." TS 15:58 "For lower-risk disease, we're paying more attention to their quality of life, how the patient's tolerating therapy, trying to help them stay safe over the long haul, and starting them on iron chelation if it matches that patient and they can have access to those drugs. ... For higher-risk disease, if the patient's goal is to be cured and not to progress to AML, you want to get them to transplant if that's [also] one of their goals. If they do evolve into AML, try and see what treatment matches best for them." TS 22:28 "You want to start early for patients who have febrile neutropenia—that's really important when a patient is an hour or two away from a center where they can get started on antibiotics. So, you have to think outside the box. What can we do to keep them safe? ... I know this group in Alaska that's in our advisory meetings and they try to facilitate transportation to Seattle. That's the closest academic center to them. Collaborating with telemedicine appointments, starting earlier, developing that strong relationship with patients, and contacting them between visits [can help patients living in rural areas]." TS 25:22 "I think the biggest [psychosocial challenge] I see is a lot of unmet anxiety and depression counseling. A lot of times, [patients are] losing their place in their family because they're the ones that need all the help now. Also, the uncertainty that goes along with the diagnosis. There is communication skills counseling, and End-of-Life Nursing Education Consortium (ELNEC) has a lot of training for communication skills and how to really talk to patients. Not that we take the place of a psychologist, but just being able to talk to somebody can go a long way. And if we can get training for that, we can help more patients." TS 31:15

Heute spreche ich in meinem Perry Rhodan Reread-Podcast Stardust ruft Terra über den 290. Band der Heftromanserie. Mit „Koordinaten ins Jenseits“ setzt Clark Darlton die Geschichte über den Kampf der Terraner auf der Heimatwelt der Sonneningenieure fort. Gucky versucht verzweifelt, seine terranischen Begleiter aus der Hand der Tefroder zu befreien, und Rhodan geht auf die Spurensuche, wo Teile seiner Mannschaft abgeblieben sind. Wie die Geschichte ausgeht und der Roman bei mir ankommt, erfahrt ihr in diesem Podcast. Zusätzlich zur Besprechung des Romans, erhaltet ihr in dieser Folge auch unsere erste Sonderfolge zum Zyklus „Die Meister der Insel“. Gemeinsam mit Dominik, Markus und Domsen unterhalte ich mich über die ersten 50 Hefte des berühmtesten Handlungsabschnittes der Serie. Ich danke Sven, Markus, Roland und Harry, dass sie sich mit einem Einspieler zu dieser Folge beteiligt haben. Wir werden natürlich auch eine Sonderfolge zur zweiten Hälfte aufnehmen. Die wird es dann zur Folge Nr. 299 geben. Wenn ihr euch mit euren Gedanken zu den Meistern beteiligen wollt, könnt ihr gern einen Text schicken oder mir euren Einspieler per Email senden. Wir sind gespannt auf euer Feedback. Wenn ihr mehr über den Weltendieb oder Stardust ruft Terra erfahren wollt, besucht den Blog. Den Link findet ihr in den Shownotes. Wenn ihr Feedback oder eure Meinung mitteilen wollt, schreibt einen Kommentar im Blogpost oder schreibt eine Mail an stardustruftterra@weltendieb.com. Ihr findet mich natürlich auch auf allen gängigen sozialen Netzwerken. Einen Überblick über alle veröffentlichten Folgen des Stardust ruft Terra Podcast findet ihr unter diesem Link. Solltet ihr beim Hören dieser Episode Lust auf andere Perry Rhodan Podcasts bekommen haben, dann schaut auf jeden Fall im WarpCast vorbei und auch bei den Freunden des Radio Freies Ertrus. Die Intromusik stammt vom Künstler  Sergey Cheremisinov. Der Song heißt Jump In Infinity und unterliegt der Creative Commons Lizenz (CC BY-NC 4.0). Ihr könnt uns finanziell auf Steady unterstützen. Dadurch bekommt ihr zeitexklusiven Zugriff auf Podcastfolgen und andere Boni. Alle Podcasts des Weltendieb bleiben frei verfügbar. Alle weiteren Informationen findet ihr unter diesem Link.  Wenn ihr #PaxTerra Sticker haben wollt, schickt eine E-Mail an info@weltendieb.com. Vergesst dabei aber nicht eure Adresse.

Summer is here - we enter the long days and sultry nights with the garden looking glorious - but always looking to the horizon for a little bit of rain to keep things looking green and lush. Herbaceous borders are set to maximum colour, vegetable beds seem to multiply in growth weekly and the gardener's tan is ever present. So enjoy the long summer days, take some time to appreciate time in your garden and join the Talking Heads pair as they continue to look after their planty spaces, as well as enjoying their gardens at home.After many weeks apart, Lucy and Saul finally catch up with each other (via Zoom) to discover what's been going on in their respective gardening lives. Saul is still recovering from The Chelsea Flower Show, and Lucy is busy prepping for her Beautiful Border at BBC Gardeners' World Live at the NEC. In the meantime, the dry spell has ended with rain falling in both Devon and Essex - giving the duo's gardens a much needed rest from the scorching conditions. If any listeners want to similarly refresh Lucy and Saul at the NEC, all biscuits are welcome!!Instagram links:Saul plantsmansaulLucy lucychamberlaingardensIntro and Outro music from https://filmmusic.io"Fireflies and Stardust" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Support the showSupport the show

"Until immunomodulators, patients [with myeloma] did not have a great overall survival rate. But when we introduced lenalidomide, we started seeing our patients have life expectancies between five and seven years—which was unheard of prior to these immunomodulators going forward. I think it's promising and allows patients to have quality of life versus therapy of life," ONS member Daniel Verina, DNP, RN, ACNP-BC, nurse practitioner for the multiple myeloma program at Mount Sinai Medical Center in New York, NY, told Lenise Taylor, MN, RN, AOCNS®, BMTCN®, oncology clinical specialist at ONS, during a conversation about immunomodulators. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by June 12, 2027. Daniel Verina is on the speakers' bureau for Johnson & Johnson, GlaxoSmithKline, and Pfizer. This financial relationship has been mitigated. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome:  Learners will report an increase in knowledge about the use of immunomodulators to treat cancer. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Pharmacology 101 series Episode 401: Multiple Myeloma Treatment Considerations for Oncology Nurses Episode 386: Interprofessional Navigation and the Oral Anticancer Medication Care Compass Episode 290: Cancer Symptom Management Basics: Peripheral Neuropathy ONS Voice articles: Maintain Oral Adherence With ONS Guidelines™ Multiple Myeloma Prevention, Screening, Treatment, and Survivorship Recommendations Sexual Considerations for Patients With Cancer Clinical Journal of Oncology Nursing article: Optimizing Transitions of Care in Multiple Myeloma Immunotherapy: Nurse Roles Oncology Nursing Forum articles: Changes in Health-Related Quality of Life During Multiple Myeloma Treatment: A Qualitative Interview Study Facilitators of Multiple Myeloma Treatment: A Qualitative Study ONS book: Multiple Myeloma: A Textbook for Nurses (third edition) ONS Symptom Intervention resource: Peripheral Neuropathy Risk Evaluation and Mitigation Strategies (REMS) Lenalidomide Pomalidomide Thalidomide International Myeloma Foundation: Using Immune Therapy to Fight Multiple Myeloma International Myeloma Society Multiple Myeloma Research Foundation: Treatments for Multiple Myeloma To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "We definitely want the diagnosis of multiple myeloma before initiating these drugs. We're going to look at serum protein electrophoresis. We want to make sure that we know the patient has serum free light chains and myeloma proteins to really confirm their disease. Plus, a bone marrow biopsy." TS 7:21 "Each immunomodulator has slightly different side effects. Thalidomide's biggest side effects are constipation, weakness, fatigue, somnolence, peripheral neuropathy, mood swings, hand tremors, and depression. With each generation, less of the side effects actually occurred. Most of lenalidomide's side effects, not discounting the deep vein thrombosis, are pancytopenia—the neutropenia, the anemia, and the thrombocytopenia. [The side effects] are very similar in pomalidomide." TS 15:40 "The REMS program is critical for oral immunomodulator therapies—thalidomide, pomalidomide, and lenalidomide. It was developed due to the risk of developing embryofetal toxicities. ... It is mandatory testing and counseling, so all females of reproductive potential must have two negative pregnancy tests prior to starting the therapy and then monthly pregnancy tests while on the therapy alone. Again, they must use two forms of effective contraceptives or abstain from heterosexual sex four weeks prior, during, and after. And the same thing for men. I focus on that because males may say, 'I have a vasectomy.' These therapies tend to bind to the semen. So, males must still use a latex or synthetic condom during any sexual contact with a female of reproductive potential, even if they did have a vasectomy." TS 18:31 "The capsule itself cannot be chewed, crushed, or opened. I bring that up because as healthcare professionals, we have educated our patients. If it's difficult to swallow capsules or tablets, we've always said to them, 'Oh, don't worry, just crush it into applesauce or open it up and sprinkle it on your mashed potatoes.' But because of this embryofetal toxicity, I advise my patients not to open the capsule. If they can't swallow it for any reason, they have a sore throat or they're just unable to, then [we tell them] to hold the therapy and then call us." TS 22:49 "We spoke about three generations already, but there's actually a fourth generation [of immunomodulators]. They're called cereblon E3 ligase modulators(CELMoDs). They're still in clinical trials but really showing promise in the therapy of myeloma. They're showing very good affinity to cereblons, just like the immunomodulators do. I think, in all cancer therapies, as newer generations come out or newer therapies move forward, some of the older generations might move aside, but they get integrated later on. So I don't think [immunomodulators] will disappear totally, but they will probably be modified." TS 36:39

Heute spreche ich in meinem Perry Rhodan Reread-Podcast Stardust ruft Terra, über den 289. Band der Heftromanserie. Mit „System der blauen Sonne“ bringt uns Clark Darlton zur Heimat der Sonneningenieure. Die Woolver Zwillinge und der Mausbiber Gucky gehen eigenmächtig auf eine gemeinsame Mission. Auf Umwegen erreich sie die Welt Hoel, auf der die Tefroder die Sonneningenieure als Geiseln halten. Wie die Geschichte ausgeht und der Roman bei mir ankommt, erfahrt ihr in diesem Podcast. Wenn ihr mehr über den Weltendieb oder Stardust ruft Terra erfahren wollt, besucht den Blog. Den Link findet ihr in den Shownotes. Wenn ihr Feedback oder eure Meinung mitteilen wollt, schreibt einen Kommentar im Blogpost oder schreibt eine Mail an stardustruftterra@weltendieb.com. Ihr findet mich natürlich auch auf allen gängigen sozialen Netzwerken. Einen Überblick über alle veröffentlichten Folgen des Stardust ruft Terra Podcast findet ihr unter diesem Link. Solltet ihr beim Hören dieser Episode Lust auf andere Perry Rhodan Podcasts bekommen haben, dann schaut auf jeden Fall im WarpCast vorbei und auch bei den Freunden des Radio Freies Ertrus. Die Intromusik stammt vom Künstler  Sergey Cheremisinov. Der Song heißt Jump In Infinity und unterliegt der Creative Commons Lizenz (CC BY-NC 4.0). Ihr könnt uns finanziell auf Steady unterstützen. Dadurch bekommt ihr zeitexklusiven Zugriff auf Podcastfolgen und andere Boni. Alle Podcasts des Weltendieb bleiben frei verfügbar. Alle weiteren Informationen findet ihr unter diesem Link.  Wenn ihr #PaxTerra Sticker haben wollt, schickt eine E-Mail an info@weltendieb.com. Vergesst dabei aber nicht eure Adresse.

DJ Erikk Raphael - 006 Stardust Sessions Haus WeRK by Ibiza Stardust Radio

"FUTURISMO IBIZA 028 hosted by CFBT on Ibiza Stardust Radio 04.06.2026 ”FUTURISMO IBIZA” is harmonic four-deck futuristic fusion of high-quality progressive house monthly journey 01. James Holden, Julie Thompson - Nothing (Savrun Brothers Remix) [White] 02. JUAN BUITRAGO - Forever Mover [Balance Music] 03. Hobin Rude - Crying Moon (Digital Mess Remix) [EKABEAT MUSIC] 04. Roger Martinez - Wanna Be With You (RM Healing Darkness Remix) [HIGHER STATES] 05. Mayro - Wabi [Traful] 06. Kate Bush vs Infusion - Running Up That Hill (Federico Monachesi Edit) [White] 07. Simos Tagias, Tonaco - Alnilam (Sebastian Sellares Remix) [Edge] 08. Digital Mess - Rusty Flower [Metanoia Soul] 09. EMPHI - Cosmic Arrival [Melorama Musica] 10. Das Pharaoh - Whispers in the Wind [UV] 11. Jamie Stevens - With You (Alex O'Rion Remix) [Music To Die For] 12. Matter - Empty Universe [Meanwhile] 13. Joey Beltram - Energy Flash (The Yellow Heads Re-Work) [White] OneLove, CFBT

Summer is here - we enter the long days and sultry nights with the garden looking glorious but always looking to the horizon for a little bit of rain to keep things looking green and lush. Herbaceous borders are set to maximum colour, vegetable beds seem to multiply in growth weekly and the gardeners tan is ever present. So enjoy the long summer days, take some time to appreciate time in your garden and join the Talking Heads pair as they continue to look after their planty spaces, as well as enjoying their gardens at home.Saul had an incredible experience at the #RHSChelseaFlowerShow, very different for his usual Monday Press Day jolly with Lucy, but instead a full on fortnight of Pavilion  , Garden promoting, media-hunting, volunteer wrangling while keeping his energy levels high (not always successful) and his brain ticking 9definitely not always successful). SO join him in this episode as he looks back at the the Flower show process and some of his highlights from the week in May where everyone talks about gardens and plants.Instagram links:Lucy lucychamberlaingardensSaul plantsmansaulIntro and Outro music from https://filmmusic.io"Fireflies and Stardust" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Support the show

Mission Stardust (1967)  aka 4…3…2…1…Morte!  aka Perry Rhodan - SOS aus dem Weltall Jeff and Cheryl bounce back and forth between the moon and the Earth with the crew of Mission Stardust. Screenplay by K.H. Vogelman, Segio Donati and Primo Zeglio Based on a story by K.H. Vogelman Directed by Primo Zeglio Starring: Lang Jeffries as Major Perry Rhodan Essy Persson as Commander Thora Luis Dávila as Mike Bull Pinkas Braun as Arkin Stefano Sibaldi as Dr Frank Haggard Daniel Martín as Captain Flipper Joachim Hansen as Dr. Manoli Janos Bartha as General Roon John Karlesen as Khrest Ann Smyrner as Dr. Joan Sheridan Lisa Halvorsen as Nurse Silva Produced by Proyziaione Europee Associates Released by Times Film Corporation Released to televison by AITV in the Fantastic Science Fiction Theater package Stream Mission Stardust on Tubi, Momentu, Fawsome, the Roku Channel or rent it on Prime Video. Visit our website - https://aippod.com/ and follow the American International Podcast on Letterboxd, Instagram and Threads @aip_pod and on Facebook at facebook.com/AmericanInternationalPodcast  Get your American International Podcast merchandise at our store. Our open and close includes clips from the following films/trailers: How to Make a Monster (1958), The Brain That Wouldn't Die (1962), I Was a Teenage Werewolf (1957), High School Hellcats (1958), Beach Blanket Bingo (1965), The Wild Angels (1966), It Conquered the World (1956), The Abominable Dr. Phibes (1971), and Female Jungle (1955) 

"Radiation therapy is often extremely well tolerated in colorectal cancer. Technology has really changed things. But location of the tumor can affect side effects, such as radiation dermatitis. If a patient has a low-lying tumor, if it's less than six centimeters from the anal verge, the patient is likely to have some skin reaction. It's good to be proactive if that's the case," ONS member Lorraine Drapek, DNP, FNP-BC, AOCNP®, nurse practitioner in the Department of Radiation Oncology at Massachusetts General Hospital in Boston, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about radiation side effects in colorectal cancer. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by June 5, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to the side effects of radiation to treat colorectal cancer. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 374: Colorectal Cancer Treatment Considerations for Nurses Episode 301: Radiation Oncology: Side Effect and Care Coordination Best Practices Episode 194: Sex Is a Component of Patient-Centered Care ONS Voice articles: Frank Conversations Enhance Sexual and Reproductive Health Support During Cancer High-Fiber Diet Reduces Diarrhea in Colorectal Cancer Survivors Hyperbaric Oxygen Therapy Shows Promise for Certain Radiation Side Effects Increasing Incidence of Colorectal Cancer in Younger Adults Is a Call to Action for Oncology Nurses Oncology Drug Reference Sheet: 5-Fluorouracil Oncology Drug Reference Sheet: Oxaliplatin Oncology Nurses Are Key in Sexual Health Conversations With Minority Women Sexual Considerations for Patients With Cancer The Intersection of Pelvic Health and Oncology Optimizes Sexual Symptom Management ONS book: Manual for Radiation Oncology Nursing Practice and Education (fifth edition) ONS courses: ONS/ONCC® Radiation Therapy Certificate™ ONS ROCN™ Certification Review™ Clinical Journal of Oncology Nursing articles: Sexual Dysfunction: Common Side Effect Updated Interventions for Radiation-Induced Diarrhea: Putting Evidence Into Practice With the Oncology Nursing Society Physical Activity: A Systematic Review to Inform Nurse Recommendations During Treatment for Colorectal Cancer ONS Learning Libraries: Colorectal Cancer Radiation Advanced Practitioner Society for Hematology and Oncology American Society for Radiation Oncology American Society of Clinical Oncology Clinical Practice Guidelines Colontown Colorectal Cancer Alliance To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "In recent years, there has been more nonsurgical management of rectal cancer, especially in what we call the low-lying population. This is the population of patients who would likely end up with a permanent colostomy because their cancer is so low in terms of being close to or involving the anal verge. There is now a regimen where these patients can get their chemotherapy followed by their chemoradiation and then be monitored on close surveillance without surgery." TS 2:23 "Another assessment would be to assess what effects have they had from their chemotherapy that they're bringing with them. FOLFOX-based treatment is commonly used, and the platinum therapy oxaliplatin often causes peripheral neuropathy. What is the patient having? What are those symptoms like? Are they having peripheral neuropathy? If they are that is likely not going to get better or improve during their whole course of radiation. In fact, sometimes when oxaliplatin therapy stops, the peripheral neuropathy can get worse as patients are going through other treatments." TS 5:42 "If the patient has a low-lying tumor, if it's less than six centimeters from the anal verge, the patient is likely to have some skin reaction. It's good to be proactive if that's the case. And then proactively minimizing radiation dermatitis effects, such as keeping the area clean, good washing of the area, and prophylactically starting them on or having someone start them on steroid creams a couple of times a day to minimize that radiation dermatitis effect in the long run." TS 7:25 "I have a sexual health clinic for women with these effects. It's very important as nurses that if you can develop the comfort to ask patients about their sexual activity—it's hard, but it really needs to be done. And I will tell you that the healthcare providers are not doing it. They don't have time, and like us as nurses, we don't get this in school, and neither do they. The other providers don't get it in school either, but it's important. Patients are getting more and more worried about their sexual health. They're coming to us at a younger age, and this is really, really important to address." TS 15:35 "I would say that working with your advanced practice providers and education for advanced practice providers has definitely been focusing on [sexual health] more. Your PAs and your NPs—I think they're going to have the ears and the wherewithal to be able to be your allies and colleagues in this. By and large, it's my APP colleagues and nursing that I talk to the most about this. … Again, it's not an easy thing to bring forward, having dilators in place. But I will tell you in the department that I work in, it was me and couple of nurses who pushed this issue with the physicians for two years and finally got it put in place. It can be done. There's a lot more centers out there doing that." TS 21:51

"There are a lot of specifics that nurses need to keep in mind as they are administering this herpes simplex modified virus to patients because accidental exposure is of concern both to the patient, to their family members, as well as to healthcare workers. I always recommend nurses wear personal protective equipment, such as a gown, safety glasses, gloves, and/or a face shield," Heidi Finnes, PharmD, RPh, BCOP, director of clinical ambulatory practice at Mayo Clinic and assistant professor of pharmacy at Mayo Clinic Alix School of Medicine in Rochester, MN, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about oncolytic viral therapy.  Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by May 29, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge about the use of oncolytic viruses to treat cancer. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Pharmacology 101 series Episode 338: High-Volume Subcutaneous Injections: The Oncology Nurse's Role Episode 330: Stay Up to Date on Safe Handling of Hazardous Drugs Episode 273: Updates in Chemotherapy and Immunotherapy ONS Voice articles: Cutaneous Malignancies Have High Response to Oncolytic Virus Plus Immunotherapy Oncolytic Virus Kills Tumor Cells While Supporting T Cells What Nurses Need to Know About Talimogene Laherparepvec for Advanced Melanoma Clinical Journal of Oncology Nursing articles: Intralesional Therapy: Consensus Statements for Best Practices in Administration From the Melanoma Nursing Initiative Safe and Effective Standards of Care: Supporting the Administration of T-VEC for Patients With Advanced Melanoma in the Outpatient Oncology Setting Oncology Nursing Forum article: Administration and Handling of Talimogene Laherparepvec: An Intralesional Oncolytic Immunotherapy for Melanoma ONS book: Guide to Cancer Immunotherapy (second edition) ONS clinical practice resource: Safe Handling of Oncolytic Viruses ONS Huddle Card: Immunotherapy Association of Community Cancer Centers (ACCC) Drugs@FDA Hematology/Oncology Pharmacy Association (HOPA) Network for Collaborative Oncology Development and Advancement (NCODA) Patient Education Sheets To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "[Oncolytic viruses] can have direct lysis to the tumor cells themselves, or they can cause immunogenic activation. They release tumor-associated antigens and then proinflammatory signals, so think of T cells, natural killer cells, those sorts of things, that can convert to immunologically cold tumors. Those are tumors that are immune silenced into hot tumors which are now immune activated. By doing that, they recruit those T cells and other cells to the area to attack both the primary tumors. But that's also thought to be how they work on distant or noninjected sites as well. This immunomodulatory capacity has led to the reclassification of oncolytic viruses as a form of cancer immunotherapy. So, think of it kind of similarly to how we think of immune checkpoint inhibitors in recruiting immune cells and leaving our immune system in the on position. This is also kind of a form of immunotherapy." TS 4:35 "One of the toxicities I know that is of significant concern to patients, family members, and healthcare workers is the incidence of herpes infections. Systemic herpetic infections are extremely rare and usually more common in patients who may be immunocompromised. In patients who also have other immune-related diseases—such as vitiligo, vasculitis, pneumonitis, sometimes worsening psoriasis—because you're mounting an immune response with these types of things, sometimes you can see a worsening of those types of immune symptoms. But for the most part, these types of side effects are very well tolerated in most patients." TS 9:07 "Talimogene is generally transmitted via bodily fluids or touch. It's not airborne. Herpes simplex virus isn't an airborne type of virus. Another thing to consider is where are you going to inject this? Are you going to do this in your infusion therapy unit? Are you going to do it in a dedicated room? Who's going to escort the patient to the room? How is the virus going to arrive at the room? How will you clean the room and all of the laboratory equipment or any of the exam tables that may be in there? I think having all of that discussed and assigned mitigates the consternation that can sometimes occur—the fear that occurs with administering a virus that is thought to be fairly communicable." TS 15:44 "Helping patients understand how this works [is important] because hearing that you're receiving a virus, particularly a herpes simplex virus, can be scary to a patient. I think understanding that it's modified or essentially we're taking the parts out of it so that we can directly inject a portion that recruits immune cells to that area, because the goal is for the oncolytic virus to attack cancer cells and then destroy them by triggering an immune response in the body." TS 20:51 "Sometimes patients are very concerned about urine in the toilet, bodily fluids, kissing loved ones, holding hands, hugging, you know, am I going to infect my loved one because I'm getting this type of an oncolytic virus therapy? I like to reassure patients that they can continue to hold hands and hug their loved ones as normal. Viral DNA is usually only present on the injection site. And as I mentioned previously, we want to cover that injection site with an occlusive dressing, at least with talimogene, for up to seven days. And particularly, if those injection sites are at all oozing or weeping, active virus is usually only on that injection site itself." TS 24:14

"For my debut Resident show on Ibiza Stardust Radio, I prepared a deep and emotional Organic House journey inspired by sunsets, warm nights and positive energy This mix includes beautiful music and inspiration from amazing artists and producers such as Alejandro Mosso, Alex Spite, HOKI, Rashid Ajami & Madraas and many more who constantly inspire me with their unique sound and atmosphere. I always try to create a story through music — something emotional, melodic and hypnotic at the same time. Hope you will enjoy this journey as much as I enjoyed creating it Big thanks to Ibiza Stardust Radio for the warm welcome to the Resident family ❤️ "

"005 Stardust Sessions Afterglow Broadcasting 05.14.2026 After the peak energy of Tribal Pulse, this session settles into the afterglow. . 00:00 Bamkile (Original Mix) – Saint Evo, Nomvula SA 04:05 Smooth Operator (Jamek Ortega Edit) – Sade 08:10 I Want To Try Again (FNX Omar Remix) – Nuzu Deep, Wheeler del Torro 12:15 Missing (Cebow M Bootleg) – Caiiro, Priscilla K 16:20 Sex On The Beach (Extended Mix) – Makid, Dave Bo 20:25 The City (Extended Mix) – Venessa Jackson, Flambe 24:30 Not Like Us (Sam Collins & Sly Phil VIP) – Kendrick Lamar 28:35 RIRI (Original Mix) – Sllash & Doppe 32:40 Let's Get Down (Original Mix) – DJ Stingray 36:45 Ain't Nothin' Goin' On But The Rent (Afro Mix) – Mattei & Omich, Re-Tide 40:50 Needed You (VIP Remix) – Sammy Porter 44:55 Take It Off (Extended Mix) – FISHER, Aatig 49:00 Chanel (No One Edit) – Tyla 53:05 The March of Anubis (Ritual Mix) – DJ Erikk Raphael 57:20 Rise of the Sun People – DJ Erikk Raphael "

" 005 Stardust Sessions Afterglow Tracklist + Timestamps 00:00 Bamkile (Original Mix) – Saint Evo, Nomvula SA 04:05 Smooth Operator (Jamek Ortega Edit) – Sade 08:10 I Want To Try Again (FNX Omar Remix) – Nuzu Deep, Wheeler del Torro 12:15 Missing (Cebow M Bootleg) – Caiiro, Priscilla K 16:20 Sex On The Beach (Extended Mix) – Makid, Dave Bo 20:25 The City (Extended Mix) – Venessa Jackson, Flambe 24:30 Not Like Us (Sam Collins & Sly Phil VIP) – Kendrick Lamar 28:35 RIRI (Original Mix) – Sllash & Doppe 32:40 Let's Get Down (Original Mix) – DJ Stingray 36:45 Ain't Nothin' Goin' On But The Rent (Afro Mix) – Mattei & Omich, Re-Tide 40:50 Needed You (VIP Remix) – Sammy Porter 44:55 Take It Off (Extended Mix) – FISHER, Aatig 49:00 Chanel (No One Edit) – Tyla 53:05 The March of Anubis (Ritual Mix) – DJ Erikk Raphael 57:20 Rise of the Sun People – DJ Erikk Raphael"

Spring is well and truly here - as clocks change, sunny days lengthen, and the occasional chilly night catches us unaware. But the main thing is plants are really starting to wake up and give us something to cheer about after a very wet and gloomy winter! Saul and Lucy look forward to really getting to grips with there gardens both at home and work - and Plant collections up and down the breathe of the UK start showing themselves at their best for all to behold. Finally the 2026 gardening year begins!Whilst the Chelsea Flower Show is keeping Mr Walker incredibly busy, Lucy has been kicking her literal heels whilst she waits for her body to heal. Luckily, there's plenty going on in the garden to keep her entertained, so join her in a 30-minute tour of Chateau Chamberlain to hear about teucriums, irises, aphids and tetrapanax. It's a horticultural smorgasbord of delights!Instagram links:Lucy lucychamberlaingardensSaul plantsmansaulIntro and Outro music from https://filmmusic.io"Fireflies and Stardust" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Support the show

This week, hosts Jim DeRogatis and Greg Kot dig into Willie Nelson's vast catalog of 150+ albums. Along with author Geoffrey Himes, they highlight the “five essential” albums people should hear. They also review the latest album from Kacey Musgraves.Join our Facebook Group: https://bit.ly/3sivr9TBecome a member on Patreon: https://bit.ly/3slWZvcSign up for our newsletter: https://bit.ly/3eEvRnGMake a donation via PayPal: https://bit.ly/3dmt9lUSend us a Voice Memo: Desktop: bit.ly/2RyD5Ah Mobile: sayhi.chat/soundops Featured Songs:Willie Nelson, "Stardust," Stardust, Columbia, 1978The Beatles, "With A Little Help From My Friends," Sgt. Pepper's Lonely Hearts Club Band, Parlophone, 1967Kacey Musgraves, "Dry Spell," Middle of Nowhere, Lost Highway, 2026Kacey Musgraves, "Middle of Nowhere," Middle of Nowhere, Lost Highway, 2026Kacey Musgraves, "Horses and Divorces (featuring Miranda Lambert)," Middle of Nowhere, Lost Highway, 2026Kacey Musgraves, "Uncertain, TX (featuring Willie Nelson)," Middle of Nowhere, Lost Highway, 2026Willie Nelson, "Blue Eyes Crying in the Rain," Red Headed Stranger, Columbia, 1975Willie Nelson, "Phases and Stages (Theme) / Washing the Dishes," Phases and Stages, Atlantic, 1974Willie Nelson, "Bloody Mary Morning," Phases and Stages, Atlantic, 1974Willie Nelson, "Help Me Make It Through the Night," Sings Kristofferson, Columbia, 1979Willie Nelson, "Georgia On My Mind," Stardust, Columbia, 1978Willie Nelson, "I Guess I've Come to Live Here in Your Eyes," Spirit, Island, 1996Willie Nelson, "On the Road Again (Live)," Live! At The US Festival (June 4, 1983), Shout! Factory, 1983Willie Nelson, "Last Man Standing," Last Man Standing, Legacy, 2018Willie Nelson, "Always on My Mind," Always on My Mind, Columbia, 1982Gary Stewart, "She's Actin' Single (I'm Drinkin' Doubles)," Out of Hand, RCA Victor, 1975See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

"When you have benign conditions, we're actually treating 3 gray, so a significant difference [versus doses of 60 gray for brain cancer]. Typically, when you treat at a high dose, the goal is to destroy tissue, like cancer tissue or cancer cells. But when we give a low dose, the goal is actually to modulate inflammation. And what it does is it slows down those inflammatory cells or those cells that release the chemicals that cause pain and inflammation," Amanda Meyer, DNP, APRN, CNP, family nurse practitioner in the Department of Radiation Oncology at the Mayo Clinic in Rochester, MN, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about radiation therapy for noncancer indications. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.25 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by May 22, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge about the use of radiation to treat noncancerous conditions. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 365: Radiation-Associated Secondary Cancers Episode 301: Radiation Oncology: Side Effect and Care Coordination Best Practices ONS Voice articles: Augmented Reality Simulations Reduce Patient Anxiety by Teaching Them About Radiation Therapy Highly Localized, Precision Radiation Therapies Require Nurses to Drive Care Coordination, Patient Education Quick Quiz: Test Your Knowledge of Radiation Care Coordination ONS book: Manual for Radiation Oncology Nursing Practice and Education (fifth edition) ONS courses: ONS Radiation Oncology Conference Recordings Bundle™ ONS ROCN™ Certification Review™ Radiation Oncology 101: 2024 ONS Bridge™ Session ONS/ONCC® Radiation Therapy Certificate™ Clinical Journal of Oncology Nursing articles: Findings From the 2023 Radiation Oncology Nursing Role Delineation Study to Shape the Future of the Subspecialty The Role of Advanced Practice Providers in Radiation Oncology in 2025 ONS Huddle Cards: Radiation Radiobiology German Society for Radiation Oncology (DEGRO): Guidelines in Radiotherapy: Radiotherapy for Benign Diseases To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "We always typically think of it as cancer treatment, but we can use radiation for noncancerous conditions, as well. And radiation was actually used for benign diseases right after the discovery of x-rays. By the 1920s it was used a lot for different types of musculoskeletal, dermatologic issues, and different types of inflammatory conditions. And over time, since the 1920s, we've actually really gotten a really good understanding of it." TS 1:37 "When we're looking at what are good candidate characteristics, we do typically like older patients, so patients over the age of 65. And the rationale behind that is we know that there is a potential for a secondary risk of a skin cancer about 20 to 30 years after getting low-dose radiation, like a basal cell or squamous cell skin cancer. The older the patient is, the less likely they are to have any adverse effects from that." TS 8:22 "When we do the low-dose radiation, they've tried other measures that haven't been successful. However, we don't want a patient who is so severe that they're ready for surgery, when they're bone on bone, because we know that radiation isn't as effective when they are that severe. So there's this sweet window where low-dose radiation works best in these patients." TS 9:39 "When we're treating with a little bit higher dose for like a Dupuytren's or a Ledderhose, because it's an anti-proliferative dose, those patients, they do get more skin redness, more dry skin. That's very temporary, and it resolves within a week or two after treatment. But really, we don't see any acute side effects. The long-term side effect of the radiation-induced malignancy, again, is a very low—0.05% according to some of the European guidelines." TS 12:34 "I really wish people appreciated how interdisciplinary this is. We need to get referrals from family medicine and from primary care and internal medicine and pain medicine physicians and inflammatory physicians and podiatry and pain specialists. And we really need to use this multidisciplinary approach to get earlier referrals for patients because there is this sweet window of time where low-dose radiation works the best." TS 18:40

WELCOME TO THE FUNK FACTORY EPISODE 474! We are turning up the heat this week with a massive, high-energy blend of heavy hitters, classic vocal flips, and absolute peak-time anthems. We're dropping huge updates to legendary tracks, from Stardust and Modjo to Lady Gaga and Nelly Furtado, alongside massive remixes of David Guetta, Pitbull, and Don Toliver. No filler, pure energy—turn the speakers up and let's get the weekend started right.Tracklist:1. French Montana & Max B - Ever Since U Left Me - The Scene Kings Remix2. Stardust - Music Sounds Better With You - JMBX & Jus Ron Remix3. Milky x David Guetta - Just The Way You Are - David Guetta Extended Mix4. Ella Langley & Morgan Wallen - I Can't Love You Anymore - Disco Fries Remix Extended5. Bruno Mars vs. Rudeejay, Da Brozz & Chico Rose feat. Robin S - I Just Might vs. Show Me Love - XMiX Dance Bootleg6. Josh Fawaz - Like A Prayer - Extended Mix7. Nelly Furtado feat. Timbaland - Promiscuous - Kamdar & Temet Remix8. Pitbull & Lil Jon - Damn I Love Miami - ApolloXO Remix9. Lady Gaga - Just Dance - Redmo Remix10. Don Toliver - Body - CLUB 909 Remix11. Quad City DJs - Space Jam - Mark Neve & Andrea Zelletta Remix12. Modjo - Lady (Hear Me Tonight) - Azooland & WREX Remix13. Justin Bieber - As Long As You Love Me - Pinto Remix14. Empire Of The Sun - Changes - Shelco Garcia & Teenwolf Remix15. Kygo, Khalid & Gryffin - Save My Love - MEDUZA Remix16. Ella Langley - Choosin' Texas - Scooter Remix

Neon Odyssey, our 1,400+ page Space Opera trilogy for D&D 5.5E, is live on Kickstarter NOW. Become a backer at https://avantr.is/neon-rpg-yt  

Harabi, Kais www.deutschlandfunk.de, Corso

Hi EveryoneI hope you can get just as excited about this research as I am. It has been around a while but I am just putting the peices together. References are below.I want you to EXPERIENCE THIS for yourself. Here are three ways NOW!Shiloh SophiaBook a call to explore our 9 month training called Stardust Initation starting in JuneJoin me for my NEW class, called Threshold - we are gonna paint aiwth power!Come along with me and my BFF Amy Ahlers to explore navigating this wild wild worldThe Neuroscience of Self-Expression: Why the Brush Knows Before We DoI want to speak to you about something I am so passionate about — the neuroscience of self-expression. It comes from my root system, because I come from the Stardust Lineage, and we are creative, spiritual, magical women who pass tools of Intentional Creativity from hand to hand and heart to heart. This isn't a woo-woo idea, and neither is it entirely scientific. It's a hybrid. Sometimes the brush knows before we know what's actually going to happen.I want to tell you about a researcher at Drexel University who has spent a decade strapping near-infrared sensors onto people's foreheads and watching what happens when the human brain is firing and wiring the moment the paintbrush touches the paper or the canvas. Do you know how long I've wanted to do this? Her name is Girija Kaimal — Wow. I would love to have a cup of tea with her. Of course, she doesn't know me. She probably will at some point, because I'm going to reach out. And she's probably never heard the words medicine painting — one of the terms we use for our work, because it's an approach to painting that's healing. Her data has been confirming what the women in our lineage have known since the 1930s. Self-expression is healing. Painting for us is a spiritual practice. It is not just a hobby. It is literally a neurological event. And guess what? When you paint with intention, the event begins before the brush ever touches the canvas. If you've worked with me, you know I talk about this all the time as energy equals matter at the speed of light — your energy as thought, expressed through your physical body, the equal sign, manifests matter at the speed of light on the canvas. Are you kidding me? Yes. The neurological awakening of what's going to happen happens before the brush touches the material.You may also be aware of another piece of research that adds to our point, by Audrey van der Meer, a Norwegian neuroscientist who has proved that writing by hand wakes up the brain in ways that typing cannot. Imagine how many kids these days are no longer learning to handwrite?! Her work is finding something so incredible about what happens when people are actually handwriting — she's measuring how the brain encodes the writing of letters into memory, and the brain is lighting up. When Kaimal's team did their research, they put 26 people in headbands — the kind that read blood flow inside the prefrontal cortex literally in real time. (Gosh, I wish it were here.) They were given three minutes to color in a mandala, to doodle around a circle, and to free-draw whatever they wanted. The results were published back in 2017 in Art Therapy. Guess what? All three activities lit up the medial prefrontal cortex. Wow. Wow. That region is part of the brain's reward pathway. Are you picking up what I'm putting down? That's the same circuit that fires when someone you love walks into the room. This is when you get to have tea with your best friend and you're jumping up and down. This is when your lover winks at you and you know what's coming next. This is when those of us in Intentional Creativity know that I'm going to do a power-packed livestream that's going to knock our red striped socks off. We feel love.The people she studied were not artists — most of them. And their brain did not care, in a literal way. Their brain didn't care if they were an artist. Their brain rewarded them anyway, for the simple act of creating color across a page with their hands. What's interesting too is that working inside of shapes — as in coloring — really does something powerful to the brain and to memory. It's just so exciting.In a separate study, the same researchers took 39 adults, gave them 45 minutes with markers, clay, and collage materials — nothing structured — and measured the cortisol in their saliva before and after. I kid you not. Cortisol in the saliva. Cortisol is the hormone your body produces under stress, the one that keeps so many of us awake at three in the morning, especially those of us going through midlife. Seventy-five percent of the participants showed lower cortisol after making art. No skill required. No talent required. No making it pretty. No perfectionism required. It is not an act of performance. It is an act of self-expression. The brain is responding to the act itself. It's in a way metacognition — becoming conscious of becoming conscious, while being intentional about what you're creating.There's something else I want to add, because when you're coloring and your brain doesn't have to make decisions, you can actually break a psychotic loop. This comes from nurses at Stanford who use my coloring books, Color of Woman. If they could get patients to color, they could break a psychotic loop. Wow. Why are we not talking about this more? Whether you're in a psychotic loop or not, wouldn't it be helpful to know that you could sit down and color and you would start to go into a different brain state? This is so important. (And it doesn't work if there's a blank page — for that psychotic-loop piece.)Now, our part in this. For close to 30 years I have been working with creating with intention, and since 2008 I've been training others to work with Intentional Creativity. I have not been teaching people to become brilliant artists — though some of them are. I have not been teaching people to make perfect paintings, though some of them do. I have not been teaching perfection technique to make a painting that would hang on the wall of a gallery. No. We've been into self-expression — to see what happens inside when you express yourself.Painting like this is a way of * Exploring our inner world. * A way of coming face to face with the often hidden identity within ourselves. * A way of activating the inner healer and the energies that go with that. * A way of catalyzing the brainwaves to move from beta to alpha to theta, so we can cross over into that state of the imagination and reach the subconscious domains. * A way of allowing the canvas itself to be a portal — to hold what the body carries* To express into form what was once inside and didn't have anywhere to go. * A composting of energy, now expressed onto the canvas. We call it medicine painting. Tens of thousands of people in our community have painted with it, and before I started doing it, we had two generations of artists who did it before me.Here's what the neuroscientists have not measured — but I would bet my brushes and my striped socks they would receive incredible results. The study in Kaimal's lab gave people markers and said, Go. There wasn't an intention set. Of course, the intention was that they were being measured. BUT. There wasn't an invocation. There wasn't a prayer. There wasn't a lighting of a candle. There wasn't a moment of asking what the piece of paper or the canvas wants to express to us. There wasn't a moment of what message are you receiving. And the cortisol still dropped. BOOOM DIGGITY. The reward pathway still lit up. The body still received a measurable gift — and the “able to experience it” part is super important to me. Because when we do this work and invite people to experience and acknowledge that it's happened, it creates more reward and more bliss and more affirmation and more faith that we could do it again and again. Which is why the science matters to me — because I want us to be able to do it again and again, in risk groups, in affinity groups, in groups of children, with people who need it. We need to bring this work everywhere.Imagine what the data would look like if the people being measured were bringing an intention. An intention to heal an illness. An intention to repair a marriage. An intention to pray for the end of war. Do you know how much power comes into the field, into the body, when one of us places our hand on the canvas and the other hand on the heart and says, What wants to be revealed? When a woman holds the red thread with other women in her circle, when she blesses the water and the cup of rain with holy water sprinkled from the places that matter to her, that brush is then charged with all of that energy. When we set an intention to alchemize trauma and wounds from years ago, patterns stuck in the body — then, when the brush expresses lightning, because we are daughters of lightning, it gets moved.In Intentional Creativity we say that the intention sets the field. This comes from Einstein's theories “the field is the sole governing agency of the particle”. The energy around us is what's creating what goes on the canvas. The thought we have and the intention we set will impact what shows up on the canvas. Then we observe it with our eyes, and the material goes back through the brain and translates back through the hands again. The moment you choose what this experience is for, the body has already started doing the work of translating the thought through the body, and the brush is just the place where the choice makes the inner vision possible — and then visible.What the neuroscience is beginning to show is that this is not metaphoric. Self-expression is not just a great idea. The state of the nervous system, before this act of beauty, this act of devotion — I'm so humbled by this. You can tell I'm just all lit up. When we come to the canvas, our nervous system is firing and wiring in a particular way. When we bring intention to the canvas, the nervous system shifts and becomes more regulated. The heart and brain can come into coherence. A brain and a mind that has been communicated with — that this sacred act will enable you to receive different signals — will receive messages you can't even imagine. Intention is a neurological primer of possibility. All meditation teachers know this. Our grandmothers who blessed the bread while kneading it, know this. Our aunties who sew the quilts know this. Every woman in our community who has ever painted herself back into her own body and told her own story — we know this. We've crossed a threshold into another way of being, and there is no way to step back from it, because once you know, you know.More studies are coming, and they will demonstrate what we have already been practicing. They will catch up to what we've already been doing. Consider what this means for us — for women in midlife, who have been carrying grief and rage and trauma and versions of ourselves we've tried to leave behind in those old relationships. We've worked it. We've gone to therapy. We've used our journals. And yet something still isn't moving. Painting with intention opens the door to a healing that most of us could never imagine was possible with something so simple — something that does not require talent. The data from these researchers shows us that the brain rewards the act of self-expression, having nothing to do with skill.You do not need to know what's going to happen. You do not need to control the outcomes. In fact, if you try to do that, your brainwaves will change and perhaps constrict. Intention does not require a known outcome. It requires inquiry and a willingness to show up and to not be in control. You don't even need to believe it's going to happen for it to work. You just need to show up. Your cortisol is going to drop anyway. Somewhere in the medial prefrontal cortex, lights begin to fire and wire. The reward begins to spark. Your nervous system registers that something on your behalf has begun. And then there's the craving — the craving to do it again.The handwriting research showed us that we lose something when we are just typing. The painting research shows us that when we bring ourselves to the canvas, we actually create wellbeing and bliss. But I want you to hear that you do not have to be talented. You do not have to know what you're called to. If you will pick up a brush with us and cross a threshold and set an intention — if you will ask the questions you've been afraid to ask in the good company of other powerful women — then we can cross the threshold together. The canvas reveals an answer. Our paintbrush is less like a brush adding color, and more like an archeologist revealing something that's already inside. Our vision is that you already have everything you need inside of you, and what we're doing is creating a condition in the field that allows it to be expressed.And so, with my heartfelt invitation and my emphatic hand motions — which you cannot see — I invite you to join me for Threshold, a brand-new class that is going to rock our world, because that's what I'm intending is going to happen, and it happens every time as long as people show up. Plus, there's a money-back guarantee. Or if you're ready to dive into the big mama codex of our work, it's called Stardust Initiation. You can find everything at musea.orgThis is Curate Shiloh Sophia, and I'm looking forward to gathering with you and transforming our brains and hearts and hands as we fire and wire together. As we say in the Stardust lineage: with our feet on the good red earth and our hands in the stars, our hearts on our sleeve and our hands in the medium, we create — and we become the oracle that we are seeking. It happens in real time. It happens right now. And it happens every time1. Van der Weel, F. R., & Van der Meer, A. L. H. (2024). Handwriting but not typewriting leads to widespread brain connectivity: A high-density EEG study with implications for the classroom. Frontiers in Psychology, 14, 1219945.https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2023.1219945/fullOpen access. The 36-student EEG study referenced in the opening of the piece. Note: the lead author is Van der Weel; Van der Meer is corresponding author and the public face of the work.2. Kaimal, G., Ayaz, H., Herres, J., Dieterich-Hartwell, R., Makwana, B., Kaiser, D. H., & Nasser, J. A. (2017). Functional near-infrared spectroscopy assessment of reward perception based on visual self-expression: Coloring, doodling, and free drawing. The Arts in Psychotherapy, 55, 85–92.https://www.sciencedirect.com/science/article/pii/S019745561630171XThe fNIRS study showing medial prefrontal cortex activation during the three art tasks. 26 participants. Doodling produced the strongest signal.3. Kaimal, G., Ray, K., & Muniz, J. (2016). Reduction of cortisol levels and participants' responses following art making. Art Therapy: Journal of the American Art Therapy Association, 33(2), 74–80.https://www.tandfonline.com/doi/full/10.1080/07421656.2016.1166832Open access. The cortisol study. 39 adults, 45 minutes of art-making, 75% showed lower cortisol afterward, no correlation with prior art experience. Get full access to Tea with the Muse at teawiththemuse.substack.com/subscribe

De zon wat 'zachter' zetten: is het sciencefiction of serieuze klimaattechnologie? Met minuscule, reflecterende stofdeeltjes in de lucht wil de Israëlisch-Amerikaanse start-up Stardust een deel van het zonlicht terug de ruimte in kaatsen - om zo de opwarming van de aarde af te remmen. Hoe serieus moeten we dit controversiële plan nemen? Wie beslist over de lucht boven ons hoofd? En hoe problematisch is het dat juist een privaat bedrijf hierin het voortouw neemt?Presentatie: Gemma VenhuizenGasten: Laura Wismans, Felix VoogtRedactie en montage: Liz DautzenbergHeeft u vragen, suggesties of ideeën over onze journalistiek? Mail dan naar onze redactie via podcast@nrc.nlZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

This week we leap to 2007 romantic fantasy adventure film Stardust. We leapt here with actor Robert De Niro. We hope you enjoy this episode.

"We want to make sure that we discuss the details of the treatment and what treatments there are, whether it's an oral drug, whether it's a subcutaneous injection or an IV injection, [the patient's] potential for responding, whether this treatment is curative or supportive, and what the number of visits are. All of those different pieces of information that go into the decision-making process are really important," ONS member Sara Tinsley-Vance, PhD, APRN, AOCN®, nurse practitioner and quality-of-life researcher at Moffitt Cancer Center in Tampa, FL, told Lenise Taylor, MN, RN, AOCNS®, TCTCN™, oncology clinical specialist at ONS, during a conversation about myelodysplastic syndrome (MDS) treatment considerations. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by May 15, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge about the treatment considerations for MDS. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 411: An Overview of Myelodysplastic Syndrome for Oncology Nurses Episode 256: Cancer Symptom Management Basics: Hematologic Complications ONS Voice articles: FDA Approves Luspatercept-Aamt for Anemia in Adults With MDS Infection Prevention for Oncology Nurses Manage Cancer-Associated Anemia With Erythropoietin-Stimulating Agents Whole-Genome Sequencing May Guide Treatment Choices for AML and MDS Clinical Journal of Oncology Nursing articles:  Reducing Effects of Hospital-Associated Deconditioning in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation Resilience in Older Adults Diagnosed With Cancer and Receiving Chemotherapy Targeted Drug Therapies: Beyond Blood Counts and Chemistries Oncology Nursing Forum article: Frailty in Patients With Hematologic Malignancies and Those Undergoing Transplantation: A Scoping Review ONS books:  BMTCN™ Certification Review Manual (second edition) Hematopoietic Stem Cell Transplantation: A Manual for Nursing Practice (third edition) ONS course: Hematopoietic Stem Cell Transplantation™ ONS Learning Library: Hematology, Cellular Therapy, and Stem Cell Transplantation ONS Symptom Intervention resources: Prevention of Infection: General Prevention of Infection: Transplant Aplastic Anemia and MDS International Foundation: MDS Drugs and Treatments Blood Cancer United: MDS Treatment HealthTree Foundation Myelodysplastic Syndromes Foundation To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "The goals that I try to consolidate to make sure they're consistent with the patient's goals are to improve their counts, especially the anemia or cytopenias. If they're getting blood transfusions, we want to reduce the number of transfusions that they receive because we know that's linked to reduced overall survival, and it really impacts quality of life. ... And then for high-risk patients, it's a more serious discussion because we know that they are the ones who can progress to acute myeloid leukemia (AML). And we're trying to delay progression to AML. That means we're trying to improve their survival and we're also trying to manage their cytopenias and decrease their infection risk." TS 2:28 "If we look at approvals for low-risk disease and high-risk disease, those were really made based on the Revised International Prognostic Scoring System (IPSS-R) and sometimes the International Prognostic Scoring System (IPSS). Under those classification systems, when we think of lower-risk MDS, we think of patients who are primarily anemic but don't have increased blasts in their bone marrow. ... For higher-risk MDS, we want to have that discussion with those patients because their life expectancy is much shorter than patients with lower-risk MDS. We want to see if hematopoietic stem cell transplant would be something that they would be interested in if they don't have a lot of comorbidities and are relatively healthy." TS 11:41 "There are a lot of things to consider—[patients'] blood counts, comorbidities, whether they're frail, and what their goals are. There are some patients where there's no way they would want to go through transplant. And some patients want to be cured, so it just depends on your patient." TS 14:22 "I think of hematopoietic allogeneic transplants as a treatment for more of the patients with higher-risk MDS. ... With the Molecular International Prognostic Scoring System (IPSS-M), a patient can have pretty good blood counts and not have increased blasts in the bone marrow. You could send them for a transplant referral upfront without having to give them additional treatment. ... There is a recent publication that said if a patient doesn't have more than 10% blast, you could refer to transplant as a first option. ... Also, if you had a lower-risk patient who is relatively young and doesn't have any other treatment options, this would also be a patient that you could refer to transplant to see if we could care for them, and then they wouldn't have to be getting transfused all the time." TS 21:12 "I think that we often think low-risk, no treatment needed, but it depends on the person. They often need ongoing supportive care to manage their symptoms even if they're not getting treatment. And just because we're not treating them, active observation, bringing them in to see how they're doing, if they've had infections, if their blood counts are changing, that is paying attention to them and doing something. Just because they're low-risk doesn't mean they don't need anything and we can just schedule for a one-year follow-up." TS 26:30

Neon Odyssey, our 1,400+ page Space Opera trilogy for D&D 5.5E, is live on Kickstarter NOW. Become a backer at https://avantr.is/neon-rpg-yt  

Neon Odyssey, our 1,400+ page Space Opera trilogy for D&D 5.5E, is coming to Kickstarter this May. Become a VIP to unlock free Neon Nights Dice and other exclusive rewards at https://avantr.is/neon-rpg-yt  

"Skin reactions, such as redness, dryness, and just irritation of the skin, can occur. Since we're irradiating the lung, we can also cause a cough, and that's due to the inflammation from the radiation. Patients can also get esophagitis if the tumor that we're treating is close to the midline of the chest near the esophagus. And probably the most common side effect that we see is fatigue," ONS member Amy MacRostie, RN, OCN®, radiation oncology nurse at St. Charles Cancer Center in Bend, OR, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about radiation side effects in lung cancer. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.25 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by May 8, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to the side effects of radiation to treat lung cancer. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 369: Lung Cancer Survivorship Considerations for Nurses Episode 363: Lung Cancer Treatment Considerations for Nurses Episode 359: Lung Cancer Screening, Early Detection, and Disparities Episode 313: Cancer Symptom Management Basics: Other Pulmonary Complications Episode 295: Cancer Symptom Management Basics: Pulmonary Embolism, Pneumonitis, and Pleural Effusion ONS Voice article: Highly Localized, Precision Radiation Therapies Require Nurses to Drive Care Coordination, Patient Education ONS book: Manual for Radiation Oncology Nursing Practice and Education (fifth edition) ONS courses: ONS/ONCC® Radiation Therapy Certificate™ ONS ROCN™ Certification Review™ ONS Radiation Learning Library ONS Guidelines™ and Symptom Intervention Resources National Comprehensive Cancer Network LUNGevity Foundation Inspire Lung Cancer Survivors Community To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "The types of radiation that can be used are external beam radiation and stereotactic body radiation treatment, or SBRT. External beam radiation is often used in combination with other treatment modalities, like chemotherapy, immunotherapy, and targeted therapy, to treat these cancers. And SBRT is usually done solo, and it's a highly precise treatment for inoperable or early-stage lung cancers." TS 1:52 "[Physicians and] providers can also help prevent side effects by reducing the dose to the heart and reducing the dose to the good lung tissue, if you will, as much as they possibly can. And this is done using intensity-modulated techniques, or IMRT. And that's where the linear accelerator sculpts the radiation beams conforming to the shape of the tumor itself." TS 6:37 "I think overall cancer treatment can lead to decreased libido and decreased sexual interest. Depression and fear can definitely play a role in this. And with lung radiation, specifically, fatigue and possibly shortness of breath with the exertion may decrease sexual interest. Nurses and providers should support the patient in their desire or lack thereof in sexual activities. We should have open discussions … and these can take place with patients about intimacy and how that can be approached in a different way that can accommodate for the side effects that the patients might be experiencing." TS 8:57 "Post-radiation scans will be abnormal. Post-radiation imaging can be misread as a progression of disease or residual disease. And I tell patients, 'Don't panic. Talk to your radiation oncologist so they can read the imaging themselves and interpret the results.' Oftentimes what's read as progression is radiation treatment sequela of scarring or fibrosis." TS 11:25

Neon Odyssey, our 1,400+ page Space Opera trilogy for D&D 5.5E, is coming to Kickstarter this May. Become a VIP to unlock free Neon Nights Dice and other exclusive rewards at https://avantr.is/neon-rpg-yt  

SpeakersMarcus “Elevation” TaylorMarcus is a sought after Transformational and Motivational speaker, pastor, filmmaker, singer and musician. He is also the CEO and creative director of Unlock Elevation, a forward-thinking transformational ecosystem that educates and empowers people from all over the world to unlock their future. Marcus is a lyrical architect on a mission to help millions build a bridge from dreams to reality through the gift and power of language.Follow Marcus: YouTube: https://bit.ly/MarcusATaylorChannelInstagram: http://bit.ly/3aLfu3PFacebook: http://bit.ly/2TB9uoiTwitter: https://bit.ly/3xXlFCPWebsite: https://bit.ly/MarcusTaylorWebsiteFREE 10 Day Challenge by Marcus Taylor: http://bit.ly/UnlockElevationPlaylist: https://evolveorexpire.com/Book Marcus to speak at your organization: https://bit.ly/BookMarcusATaylorBobby Maximushttps://www.youtube.com/channel/UCSzAriYndMjGjJciDYyj47whttps://www.instagram.com/bobbymaximus/https://www.tiktok.com/@bobbymaximushttps://www.bobbymaximus.com/Music: AudiojungleReally Slow Motion - Made of Stardust, Impulse Asura, Return to LifeBuy their music:Amazon : http://amzn.to/1lTltY5iTunes: http://bit.ly/1ee3l8KSpotify: http://bit.ly/1r3lPvNBandcamp: http://bit.ly/1DqtZSoTwelve Titanshttps://www.twelvetitansmusic.com/ Hosted on Acast. See acast.com/privacy for more information.

DAREDEVIL SEASON 2 FINALE BREAKDOWN!! Join us LIVE as we break down the explosive Daredevil: Born Again Season 2 Finale—a game-changing episode that brings Matt Murdock's battle with Wilson Fisk to a dramatic and shocking conclusion! In this finale, Charlie Cox (Daredevil, Stardust) as Matt Murdock / Daredevil takes center stage in a gripping courtroom showdown, returning at the last moment to dismantle Fisk's case with powerful testimony and a bold reveal that shakes the entire city. Opposing him, Vincent D'Onofrio (Full Metal Jacket, Law & Order: Criminal Intent) as Wilson Fisk / Kingpin faces his most public unraveling yet, as secrets, corruption, and abuse of power come crashing into the spotlight. We'll be discussing major moments from the episode, including the shocking reveal of Daredevil's identity in open court, the chaos unleashed by Bullseye (Wilson Bethel — Hart of Dixie, All Rise), and the all-out conflict at City Hall as Fisk declares a state of emergency and protesters clash with authorities. The episode also features key appearances from Jessica Jones (Krysten Ritter — Jessica Jones, Breaking Bad), and ties into the wider street-level MCU, with mentions of Luke Cage (Mike Colter — Luke Cage, Evil) and the evolving power dynamics across New York. We'll also dive into the finale's biggest themes and consequences—Matt's ultimate sacrifice, Fisk's fate, the rise of new players like BB and Glenn, and what this means for the future of Daredevil and Marvel's street-level heroes. From intense action to courtroom drama and shocking character decisions, this finale sets the stage for what's next in the MCU. #DaredevilBornAgain #Daredevil #Marvel #MCU #Kingpin #Bullseye #JessicaJones #DisneyPlus #MarvelStudios #MCUFinale #TVReaction #LiveStream #DaredevilFinale #Punisher #ThePunisher #JessicaJones #LukeCage #JonBernthal #KristenRitter #ThePunisherOneLastKill #SpiderManBrandNewDay #ReelRejects #TheRealRejectsPodcast Follow Aaron On Instagram: https://www.instagram.com/therealaaronalexander/?hl=en Follow Andrew Gordon on Socials:  YouTube: https://www.youtube.com/@MovieSource Instagram:  https://www.instagram.com/agor711/?hl=en Twitter:  https://twitter.com/Agor711 Follow Coy Jandreau:  Tik Tok: https://www.tiktok.com/@coyjandreau?l... Instagram: https://www.instagram.com/coyjandreau/?hl=en Twitter:  https://twitter.com/CoyJandreau YouTube: https://www.youtube.com/channel/UCwYH2szDTuU9ImFZ9gBRH8w Intense Suspense by Audionautix is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... Support The Channel By Getting Some REEL REJECTS Apparel! https://www.rejectnationshop.com/ Follow Us On Socials:  Instagram: https://www.instagram.com/reelrejects/  Tik-Tok: https://www.tiktok.com/@reelrejects?lang=en Twitter: https://x.com/reelrejects Facebook: https://www.facebook.com/TheReelRejects/ Music Used In Ad:  Hat the Jazz by Twin Musicom is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Happy Alley by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... POWERED BY @GFUEL Visit https://gfuel.ly/3wD5Ygo and use code REJECTNATION for 20% off select tubs!! Head Editor: https://www.instagram.com/praperhq/?hl=en Co-Editor: Greg Alba Co-Editor: John Humphrey Music In Video: Airport Lounge - Disco Ultralounge by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Ask Us A QUESTION On CAMEO: https://www.cameo.com/thereelrejects Follow TheReelRejects On FACEBOOK, TWITTER, & INSTAGRAM:  FB:  https://www.facebook.com/TheReelRejects/ INSTAGRAM:  https://www.instagram.com/reelrejects/ TWITTER:  https://twitter.com/thereelrejects Follow GREG ON INSTAGRAM & TWITTER: INSTAGRAM:  https://www.instagram.com/thegregalba/ TWITTER:  https://twitter.com/thegregalba Learn more about your ad choices. Visit megaphone.fm/adchoices

Bridget, Caitlin, and Hilda finish their recap and review of "Cinder Vale," book 3 in Caroline Peckham and Suzanne Valenti's Sins of the Zodiac series. So you know what that means ... they got to the end so they can discuss THAT ENDING. They now understand all the DMs and texts they got about it. So don't listen just yet if you haven't finished or don't want to be spoiled. As to the rest of you: Let the happy squeals begin! Join our Patreon for exclusive behind-the-scenes content and let's be friends!Instagram > @Booktokmademe_podTikTok > @BooktokMadeMe

Nobody can question the perfect casting of Charlie Cox as Matt Murdoch aka Daredevil now but it wasn't so long before that opportunity came that Charlie was questioning his career and pondering another job to support himself. Charlie joins Josh at this live taping at the 92nd Street Y to talk about all of it, his big break in STARDUST, his friendship (including a surprise appearance via video message!) with Tom Hiddleston, and why he wouldn't trade Daredevil for Batman. SUPPORT THE SHOW BY SUPPORTING OUR SPONSORS! Rula -- Rula patients typically pay $15 per session when using insurance. Connect with quality therapists and mental health experts who specialize in you at ⁠https://www.rula.com/happy⁠ #rulapod Quince -- Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Quince.com/HAPPYSAD ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠for free shipping and 365-day returns. Limited Time Offer–Get Huel today with my exclusive offer of 15% OFF online with my code happy15 at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://huel.com/happy15.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ New Customers Only. Thank you to Huel for partnering and supporting our show! UPCOMING EVENTS! 5/5 -- Stanley Tucci in NY -- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Tickets here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 5/13 -- Matt & Ross Duffer in LA -- ⁠⁠⁠⁠⁠⁠Tickets here⁠⁠⁠⁠⁠⁠ 5/17 -- Billy Eichner in NY -- ⁠⁠⁠⁠⁠⁠⁠⁠Tickets here⁠⁠⁠ 5/18 -- Power Ballad w/Paul Rudd & Nick Jonas -- ⁠Tickets here⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Spring is well and truly here - as clocks change, sunny days lengthen, and the occasional chilly night catches us unaware. But the main thing is plants are really starting to wake up and give us something to cheer about after a very wet and gloomy winter! Saul and Lucy look forward to really getting to grips with there gardens both at home and work - and Plant collections up and down the breathe of the UK start showing themselves at their best for all to behold. Finally the 2026 gardening year begins!With Saul having a well deserved rest up in the Shetland Islands, Lucy focuses her attention on the BBC Gardeners' World Spring Fair in Beaulieu, where she's putting together a Beautiful Border along with De-Graft Mensah to promote the Gardeners' World Make a Metre Matter campaign. This, along with her usual kitchen garden tours with the Beaulieu garden team, plus some appearances on the Gardeners' World magazine main stage, has kept her quite busy.... If you want to see her experience, watch her latest reels on her Instagram profile (link below) but if you fancy a half-hour episode describing this process, download away! Instagram links:Lucy lucychamberlaingardensSaul plantsmansaulIntro and Outro music from https://filmmusic.io"Fireflies and Stardust" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)Support the show

"We thought, from a nursing standpoint, 'What is our goal for doing this?' What we wanted was first, education of the patient. Can we successfully educate the patient to prepare them? Can we alleviate as much anxiety as possible so that they feel comfortable coming in and having this done? The second goal is to preserve kidney function throughout the treatment. To date, we've been successful with that. And the third goal is to complete treatment without infection," ONS member Chris Amoroso, BSN, RN, OCN®, registered nurse at Fox Chase Cancer Center in Philadelphia, PA, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about intrarenal administration for upper urothelial tract disease. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by May 1, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Nurses caring for people with cancer require knowledge of the different routes for drug administration, including intrarenal administration via a percutaneous nephrostomy. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 141: Care Coordination for Urothelial Cancer Episode 133: Treatment Advancements for Advanced or Metastatic Urothelial Cancer ONS Voice articles: A Primer on Urothelial Cancer Chemo Combo May Be a Bladder Cancer Treatment Alternative During BCG Shortage Nurses Are Key to Patients Navigating Genitourinary Cancers Clinical Journal of Oncology Nursing articles: Avelumab First-Line Maintenance Therapy: Managing Patients With Advanced Urothelial Carcinoma Percutaneous Nephrostomy Infusion: Nursing Considerations for Treatment of Upper Urinary Tract Urothelial Carcinoma ONS Learning Libraries: Cancer of the Genitourinary Tract Safe Handling of Hazardous Drugs To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "In an office setting, it's not something we can really visualize. Patients will present with hematuria or flank pain, obstructions in the ureter, some hydronephrosis, they may be having a lot of urinary tract infections. And a routine cystoscopy in the office is not going to visualize the ureters. We can do biopsies like a ureteroscopy, a computerized tomography urogram, or a urine cytology. And those are usually the main ways of diagnosing upper tract disease—again, because it's rare." TS 2:33 "We ask patients to get into a comfortable position where they can sit or lay for an hour without too much movement. The movement of their body position can interfere with the flow of the medication going in. ... When we're ready to start, we're cleaning the ends of the nephrostomy tube and the IV tubing with a chlorhexidine solution. We're instilling this using micro drip tubing. The tubing has to be microchipped so we can accurately control the flow. The IV bag with medication is hung about 10 inches above kidney level. And the reason we do that is because we do not want to increase the intrarenal pressure. ... We want a slow infusion via gravity over about an hour. We're watching throughout the procedure to make sure that there's no leakage, no discomfort, really just watching the patient and having that communication with the patient. Are they feeling anything different? Do we notice a difference in the flow rate? Is it slowing down? And if so, why is it? Did the patient change position? If we have any [instance] where the patient says, 'I can feel something there,' or we see leakage, we stop that infusion immediately, emphasizing that it has to be gravity, never on a pump." TS 7:30 "We go over all the bacillus Calmette-Guérin (BCG) precautions because this is the drug that we're giving. As if we were doing traditional intravesical therapy such as placing a catheter up into the bladder, we're still giving patients BCG. So, we need them to follow the special precautions. We ask every patient, regardless of the drug we're giving them, to sit down to urinate, pour two cups of bleach in the toilet, let it sit for about 15 minutes, then close the lid and flush twice. Even though we're giving this for upper tract disease, it's still being excreted into the urine. So, precautions need to be followed. Sitting down to urinate to avoid splashing of the drug, putting the two cups of bleach in every time they urinate for a duration of six hours, closing the lid, and then flushing that toilet twice. The same precautions, whether it's traditional intravesical or intrarenal." TS 14:20 "The induction phase is the first six installations. So, the first time we give this drug, we're doing it once a week for six weeks. And during those six weeks, we're communicating with the patient. We'll do a follow-up phone call and ask, 'How are you feeling? Any issues?' And we do get to know our patients really well. ... If they call, we're going to send them for a urine culture and make sure there's nothing there. ... After those six weeks, we make sure the patient understands that this is not one course and done. We want to continue to do this to give them the best chance at preventing recurrence. After we've done those six, we'll wait about four to six weeks, and then we'll do a cystoscopy and ureteroscopy in the operating room to make sure we have the response we're looking for. Again, letting the patients know because sometimes they don't understand that this is going to continue—it's not six treatments and done." TS 23:08 "You can't think of this as the same as bladder cancer. This is in the upper tract. We can't approach it as if it was non-muscular invasive bladder cancer. The diagnosis is different. It's harder to diagnose. Again, we're not visualizing the ureters in a routine office cystoscopy.  ... You can't resect it out. When I was talking to our surgeon, he said, 'You can't resect the urothelial disease in the ureters like you would in a bladder tumor.' You can't go and just pick it apart. It's a little bit more complex than that. You can't go in and resect out lesions in the ureter itself." TS 36:20

Neon Odyssey, our 1,400+ page Space Opera trilogy for D&D 5.5E, is coming to Kickstarter this May. Become a VIP to unlock free Neon Nights Dice and other exclusive rewards at https://avantr.is/neon-rpg-yt  

Bridget, Caitlin, and Hilda heard your pleas and they're here with part 1 of "Cinder Vale," the third book in the Sins of the Zodiac series by the Twisted Sisters, Caroline Peckham and Suzanne Valenti. They cover the first 50% of the book ... which means you'll need to come back next episode to hear ABOUT THAT ENDING!!! Join our Patreon for exclusive behind-the-scenes content and let's be friends!Instagram > @Booktokmademe_podTikTok > @BooktokMadeMe

Rise up comrade, and rage against the machine, as on this month's episode of Forgotten Melodies we're talking about Protest Songs!With Eleanor still recovering from her operation, we brought back-up this time, in the shape of Katie Sommers, Eleanor's long-time partner in puppet theatre company Rust & Stardust. If you're a regular listener than you will hear Katie's singing voice regularly, but on this episode she speaks!What about? Well, three different songs exploring three different historical causes of protests in England!The first, Goose and the Common, is all about land rights and enclosure.The second, Rigs of the Times, is about profiteering - originally following the French Revolution.The third, The Blackleg Miner, is about strike breaking.Along the way, we - Katie, Ben, Eleanor and Martin - all discuss various aspects of these protest songs, things we feel like protesting, and protest movements in general - and we very much hope you enjoy the episode!Speak to you again on Thursday for our Lang Fairy Tale double-bill featuring The Enchanted Pig and Norka before Friday's May Update Episode and Saturday's Three Ravens Live recording from our appearance last month at Treadwells Books!The Three Ravens is a Myth and Folklore podcast hosted by award-winning writers Martin Vaux and Eleanor Conlon.Released on Mondays, each weekly episode focuses on a historic county, exploring the heritage, folklore and traditions of the area, from ghosts and mermaids to mythical monsters, half-forgotten heroes, bloody legends, and much, much more. Then, and most importantly, the pair take turns to tell a new version of an ancient story from that county - all before discussing what that tale might mean, where it might have come from, and the truths it reveals about England's hidden past...Bonus Episodes are released on Thursdays plus Local Legends episodes on Saturdays - interviews with acclaimed authors, folklorists, podcasters and historians with unique perspectives on that week's county.With a range of exclusive content on Patreon too, including audio ghost tours, the Three Ravens Newsletter, and monthly Three Ravens Film Club episodes about folk horror films from across the decades, why not join us around the campfire and listen in?REGISTER FOR THE TALES OF SOUTHERN ENGLAND TOURVisit our website Join our Patreon Social media channels and sponsors Hosted on Acast. See acast.com/privacy for more information.

What is the secret to making it on Broadway? Ellen Hart says it's practice, grit, and serving milkshakes at Ellen's Stardust Diner. As the owner of Ellen's Stardust Diner, Ellen Hart shares how she turned a retro diner into a world-famous talent incubator. From her days as Miss Subway 1959 to hosting mayors and future Tony Award winners, Ellen shares the highs and lows of building a New York City institution. Learn more about your ad choices. Visit podcastchoices.com/adchoices

"They are small, powerful little nuggets. They are actually small signaling proteins that our immune cells use to communicate. They really help regulate immune activation or inflammation and even the growth and survival of immune cells. When cytokines are used therapeutically in oncology, they help to stimulate immune cells such as T cells or natural killer cells to better recognize and attack cancer cells," Maribel Pereiras, PharmD, BCPS, BCOP, clinical pharmacy specialist at the John Theurer Cancer Center of Hackensack University Medical Center in New Jersey, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about the cytokine drug class. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours (including 30 minutes of pharmacotherapeutic content) of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by April 24, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Nurses caring for people with cancer require knowledge of cytokines to provide appropriate education and to safely administer related therapies. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Pharmacology 101 series Episode 256: Cancer Symptom Management Basics: Hematologic Complications Episode 196: Oncologic Emergencies 101: Bleeding and Thrombosis ONS Voice articles: FDA Approves Nogapendekin Alfa Inbakicept-Pmln for BCG-Unresponsive Non–Muscle Invasive Bladder Cancer Manage Cancer-Associated Anemia With Erythropoietin-Stimulating Agents Oncology Drug Reference Sheet: Motixafortide ONS books: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) and 2024 Drug Supplement Clinical Guide to Antineoplastic Therapy: A Chemotherapy Handbook (fourth edition) Guide to Cancer Immunotherapy (second edition) Clinical Journal of Oncology Nursing article: Tumor-Infiltrating Lymphocyte Therapy for Melanoma: Nursing Considerations What's Old Is New Again, Unfortunately ONS Symptom Interventions Colony-Stimulating Factors Including Biosimilars for At-Risk Patients for Prevention of Infection: General Platelet Growth Factors for Prevention of Bleeding National Comprehensive Cancer Network To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Cytokines are actually among some of the earliest forms of immunotherapy used in the treatment of cancer, and it really goes back to the 1980s and the 1990s. We're talking therapies like interferon [alpha] or interleukin-2 that were used to stimulate the immune system, with the idea that they would recognize and attack cancer cells, particularly in diseases like metastatic melanoma and renal cell carcinoma. What made these therapies unique was that although the overall response rates were relatively modest, when patients did respond, those responses could be very durable and sometimes long lasting. And that observation was really important for the field of oncology, because it was part of the process that demonstrated that the immune system could potentially control cancer in really meaningful ways." TS 1:49 "One nice new example of an engineered cytokine is nogapendekin alfa inbakicept, which is quite the tongue twister to say. … This agent is really interesting because it's an engineered interleukin-15 receptor agonist that works on stimulating natural killer cells and CD8-positive T cells. And what makes this so interesting is that it's used in combination with a medication that probably some of us are familiar with—good old BCG—for patients specifically with invasive bladder cancer. The other really interesting thing about this new therapy is the fact that it is one of our first ones to be engineered in a combination fashion. So the nogapendekin alfa is combined with a receptor component that is called inbakicept. And what happens is it forms a complex to enhance signaling and prolong the activity of the cytokine." TS 7:50 "When you're looking at our therapeutic cytokines, those tend to produce larger-scale systemic inflammatory effects leading to much more global side effect reactions, while your supportive care cytokines are more commonly associated with either bone marrow stimulation effects or hematologic changes." TS 14:01 "Regardless of what type of cytokine therapy may you be using, across the board, early recognition of the symptoms and proactive supportive care are really important. And this is where many of our oncology nurses play such a critical role in identifying changes that are happening in real time to the patient's condition and helping to coordinate, relay information to the rest of the providing team so that timely interventions can occur for the best care of the patient." TS 18:01 "The other fascinating thing about these cytokines is that they're not being used as monotherapy anymore. They're now being looked at in combination with other therapies or even other immunotherapies like our checkpoint inhibitors. They're being looked at in the sense that they may be able to help expand and further activate immune cells that our current therapies rely on. And so it's really interesting that while cytokines were some of the earliest forms of cancer immunotherapy, they're now being reimagined as part of modern combination strategies designed to really further help enhance the immune responses against cancer." TS 29:08

Could the ingredients for life have arrived on asteroids? Neil deGrasse Tyson and comic co-host Chuck Nice unpack what the sample collected from asteroid Bennu is teaching us about the origins of life itself with Harold Connolly, geologist and mission scientist for OSIRIS-REx. NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here:  https://startalkmedia.com/show/secrets-of-asteroid-bennu-with-harold-connolly-jr/ Thanks to our Patrons Kevin Widener, WilfriedLepuschitz, Rodney Juste, Aladin Mihai, Marc Washington, david smith, Gary Flenthrope, Christian Becker, EricRobert, Sonya a, Steve Jones, leeinalaska, Sewit Haile, Edward Janezich, Miguel Rodriguez, Shea M, Mister E, G.Montagnard, Vincent Jenkins, Ryan B, Brandon Kavulla, Owoskeun Cinder, LehensGivris, Marc, Debbie Evercloud, Fakhreddine Madi, Logan Koehler, Cem Oğuz, Aaron Greeley, Ohad Meir, Paul Osborne, Bodnár Márton János, STRS, Lawrence, THEO NNEBE, Richard Mosby, Kenneth Hawley, Robert Wilson, Amelia Cooper, mabus98, Mandana Rad, Lucas Kiil, Channing Hodges, Elizabeth Newton, Sebastián Egaña, Eric Hall, Sondre Rypdal, Anne Shirley, Andrew Rosenfeld, Michael Owen, T Playle, Kevin Selman, david Aldridge, Raymond Wright, Biotoxin, Brittany, Wraptile, Frances Cooley, Rodney Bell, Hesam Eskandari, Patrick Dietz, Alexandre Malouin, Diana Smith, Jesse Hoffman, Ian Peterson, WickedProf, Jonathan, SUSAN Moore, Tom DeGerlia, Jessica Holden, Simeon Ivaylov Petrov, Dario Kubler, Robert Passeri, Jr., Fred Miller, Jason Delancey, Rory L, Alice Kelaine Harline Davis, Loonertick, Rich, Jason Rich, jon meier, Susan, Robert Christine, Simon, Lauren Zajac, Brandon Abramovitz, J Sauce, Christopher Smith, Suzan Stocker, Roch Dylla, Treven Price, Zippo, Preet Sandhawalia, Chris McAfee, Hoth, Cody Mecham, Lewis, Casey Hampton, Jason Beezley, and Anthony Gliganic for supporting us this week. Subscribe to SiriusXM Podcasts+ to listen to new episodes of StarTalk Radio ad-free and a whole week early.Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In the year 2000, four pre-teen girls in Santa Rosa — three 11-year-olds, and one 9-year-old little sister — wrote and recorded an album inspired by the Spice Girls, Destiny's Child and Fiona Apple, and even filmed music videos for the album. Then, their band X-Cetra disbanded as the elder members entered junior high and found the entire project — to use the slang of today's kids — cringe. Decades later, online experimental music nerds discovered the album, with its haunting child vocals and startling low-fi beats, and turned it into a cult hit, garnering X-Cetra a record contract and a 25th anniversary reissue. A new film “Summer 2000: The X-Cetra Story,” which won the South by Southwest documentary jury award last month, documents the reunion of X-Cetra, many of whose members hadn't made art since. We'll talk with the band about what it means to revisit childhood creativity in adulthood, and we'll hear from you: Were you more creative as a tween than you are now? Have you returned to the art you made? Guests: Ayden Mayeri, member, X-Cetra; director, "Summer 2000: The X-Cetra Story" Jessica Hall, member, X-Cetra Robin O'Brien, musician; producer of X-Cetra's 2000 album, “Stardust"; mom of X-Cetra members Janet and Mary Brittany Spanos, music journalist who wrote the Rolling Stone profile, “Four Best Friends Made an Album as Kids. 25 Years Later, It's a Cult Classic” Learn more about your ad choices. Visit megaphone.fm/adchoices