Podcasts about aramini

The time has come for the first episode on Gene Wolfe! Wolfe scholar Marc Aramini joins the show to discuss this amazingly unique author. We talked about Wolfe's life, his major themes, how he uses sexuality in his fiction, his intense fan base and much more. Enjoy! Marc Aramini's Books: Between Light and Shadow: An Exploration of the Fiction of Gene Wolfe, 1951 to 1986 Beyond Time and Memory: An Exploration of the Fiction of Gene Wolfe, 1987-1990 The Wolfe's Lair: Critical Essays on Gene Wolfe published by Ktistec Press (editor) - not published yet ************************************************************************************************************* Follow me on Twitter @AaronIrber Donate to my Patreon - I Might Believe in Faeries https://www.patreon.com/imightbelieveinfaeries Like my Facebook page - I Might Believe in Faeries Battle Of The Creek by Alexander Nakarada | https://www.serpentsoundstudios.com Music promoted by https://www.free-stock-music.com Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/ Logo Art by Linnea Kisby *************************************************************************************************************

Anthony Aramini helps business owners remove themselves from taking sales calls and grow their sales team. He's personally collected over $6.67m in sales and enrolled 486 clients into high-ticket programs in 24 months. He's coached and trained thousands of closers and business owners from all around the world to master the art of transformational enrollment. Which is the art of getting prospects to enroll themselves. As well as Pre-Conversion, which is the art of pre-handling and preventing sales objections before you get to the close. He consistently delivers free sales training for closers and business owners through his Facebook Group - The Infinite Closer Method. And would love to share a free helpful resource with you when you join his group, on the 4-part framework he's used to overcome objections and collect $6.67m in sales in 24 months. In it you will gain access to the 4-part framework, and the exact scripts on how to use it immediately, to incinerate common objections like, "I need to think about it", "I need to speak with my (spouse/business partner)", fear and skepticism To access it for free, go here: https://www.facebook.com/groups/infiniteclosermethod

“Sales is the most entrepreneurial job you can be in. If you want to be an entrepreneur, sales is first, everything else is after. There is no business, if there is no sales.”In today's podcast, Anthony Aramini, a respected coach, graciously opened up about his personal journey. He discusses his transition from being a college student to making the bold decision of leaving his studies behind to fully pursue his newfound passion for coaching.During the discussion, Anthony shared the compelling reasons behind his deep affection for coaching and how it has become his true calling in life.Moreover, he delved into how he has been instrumental in guiding and supporting his clients, enabling them to achieve remarkable success in their respective endeavors.If you're curious about Anthony's inspiring story and his profound impact as a coach, I highly recommend tuning in to this podcast episode.It offers invaluable insights into the transformative power of coaching and how it has positively influenced the lives of countless individuals.Learn more about Anthony Aramini's inspiring story by checking out these links!Instagram: Anthony AraminiFacebook: Anthony Aramini Facebook

Quelle est la réalité du racisme à l'école ? Quelles approches pour prévenir la stigmatisation et le rejet de la différence ?   La prévention du racisme et de l'antisémitisme est une priorité affichée de l'École républicaine. Mais les enseignants et les personnels des collèges et lycées sont souvent démunis ou perplexes pour enclencher des actions de prévention. Parler du racisme dans les écoles peut-il contribuer à l'alimenter ?   Avec : - Aurélien Aramini, enseignant de Philosophie en classes préparatoires dans l'est de la France et chargé de mission académique dans le cadre d'un partenariat avec la Plateforme internationale sur le Racisme et l'Antisémitisme (PIRA), auteur de Du racisme et des jeunes - Témoignages de profs et d'élèves (Éditions de l'Aube) - Radouane M'hamdi, proviseur du Lycée André Boulloche de Livry Gargan, en Seine-Saint-Denis et membre du Snpden-Unsa, syndicat des personnels de direction de l'Éducation nationale.  Et un micro-trottoir de Charlie Dupiot, partie à la rencontre de lycéennes. Kady et Cassandra ont 17 ans, Alésia en a 18. Elles sont toutes les trois élèves dans un lycée professionnel des métiers de l'hôtellerie-restauration à Paris, dans le XVIIIème arrondissement. Au micro de notre reporter Charlie Dupiot, elles nous racontent ce que le mot «racisme» leur évoque. Et elles font d'abord un petit état des lieux de la diversité dans leur lycée.  En fin d'émission la chronique du psychologue Ibrahima Giroux, Parents, enfants, d'ici et d'ailleurs : Comment considérer les épreuves et aider vos enfants à redécoller après les chocs ?  À télécharger ici Un rendez-vous hebdomadaire pour aider les parents, Ibrahima Giroux est psychologue, à Dakar, Sénégal.  Programmation musicale :  ► Malpolis - Kalash et Damso  ► Leave me Alone - CKay. 

Quelle est la réalité du racisme à l'école ? Quelles approches pour prévenir la stigmatisation et le rejet de la différence ?   La prévention du racisme et de l'antisémitisme est une priorité affichée de l'École républicaine. Mais les enseignants et les personnels des collèges et lycées sont souvent démunis ou perplexes pour enclencher des actions de prévention. Parler du racisme dans les écoles peut-il contribuer à l'alimenter ?   Avec : - Aurélien Aramini, enseignant de Philosophie en classes préparatoires dans l'est de la France et chargé de mission académique dans le cadre d'un partenariat avec la Plateforme internationale sur le Racisme et l'Antisémitisme (PIRA), auteur de Du racisme et des jeunes - Témoignages de profs et d'élèves (Éditions de l'Aube) - Radouane M'hamdi, proviseur du Lycée André Boulloche de Livry Gargan, en Seine-Saint-Denis et membre du Snpden-Unsa, syndicat des personnels de direction de l'Éducation nationale.  Et un micro-trottoir de Charlie Dupiot, partie à la rencontre de lycéennes. Kady et Cassandra ont 17 ans, Alésia en a 18. Elles sont toutes les trois élèves dans un lycée professionnel des métiers de l'hôtellerie-restauration à Paris, dans le XVIIIème arrondissement. Au micro de notre reporter Charlie Dupiot, elles nous racontent ce que le mot «racisme» leur évoque. Et elles font d'abord un petit état des lieux de la diversité dans leur lycée.  En fin d'émission la chronique du psychologue Ibrahima Giroux, Parents, enfants, d'ici et d'ailleurs : Comment considérer les épreuves et aider vos enfants à redécoller après les chocs ?  À télécharger ici Un rendez-vous hebdomadaire pour aider les parents, Ibrahima Giroux est psychologue, à Dakar, Sénégal.  Programmation musicale :  ► Malpolis - Kalash et Damso  ► Leave me Alone - CKay. 

durée : 00:04:18 - Le coup de coeur des libraires France Bleu Belfort Montbéliard

Marc Aramini is not having it with our exoneration of Morwenna and putting the blame on poor flower-gifting Eusebia.  - Did we leave something out? To issue your questions, comments, and complaints, shoot us an email at rereadingwolfe@gmail.com or hit us on Facebook ...or on Twitter @rereadingwolfe ...or on Instagram: rereadingwolfepodcast ...or on Reddit: rereadingwolfepodcast  - You can get episodes on your podcast app or on our Youtube channel. Note: Youtube subscribers in some locales might not be able to access all the episodes. However, you can get every episodes at the website and on your favorite podcast app.  If you have problems accessing the podcast on your favorite platform, let us know. - * Bumper music from "You Was Wrong" by Freddy King * Logo art by SonOfWitz   

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.25.267195v1?rss=1 Authors: Gagne, D., Azad, R., Edupuganti, U. R., Williams, J., Aramini, J. M., Akasaka, K., Gardner, K. H. Abstract: Small molecule binding within internal cavities provides a way to control protein function and structure, as exhibited in numerous natural and artificial settings. Unfortunately, most ways to identify suitable cavities require high-resolution structures a priori and may miss potential cryptic sites. Here we address this limitation via high-pressure solution NMR spectroscopy, taking advantage of the distinctive nonlinear pressure-induced chemical shift changes observed in proteins containing internal cavities and voids. We developed a method to rapidly characterize such nonlinearity among backbone 1H and 15N amide signals without needing to have sequence-specific chemical shift assignments, taking advantage of routinely available 15N-labeled samples, instrumentation, and 2D 1H/15N HSQC experiments. From such data, we find a strong correlation in the site-to-site variability in such nonlinearity with the total void volume within proteins, providing insights useful for prioritizing domains for ligand binding and indicating mode-of-action among such protein/ligand systems. We suggest that this approach provides a rapid and useful way to rapidly assess otherwise hidden dynamic architectures of protein that reflect fundamental properties associated with ligand binding and control. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.29.227322v1?rss=1 Authors: Xu, X., Gagne, D., Aramini, J. M., Gardner, K. H. Abstract: Proteins often interconvert between different conformations in ways critical to their function. However, manipulating the equilibrium positions and kinetics of such conformational transitions has been traditionally challenging. Pressure is an effective thermodynamic variable for favoring the population of high energy protein conformational states with smaller volumes, as elegantly demonstrated in its use for biophysical studies of unfolding transitions. Here, we investigate the pressure-dependent effects of the interconversion of two stably-folded conformations of the Y456T variant of the aryl hydrocarbon receptor nuclear translocator (ARNT) Period/ARNT/Single-minded PAS-B domain. We previously discovered that ARNT PAS-B Y456T spontaneously interconverts between two structures primarily differing by a three-residue {beta}-strand slip, inverting its topology in the process. This change collapses the internal cavities of the WT-like (WT) conformation of this protein as it adopts the slipped conformation (SLIP). Using pressure-NMR to conduct thermodynamic and kinetic analyses of the interconversion of ARNT PAS-B, we provide data that support two key predictions of this process: the SLIP conformation is both smaller and less compressible than the WT conformation, and the interconversion proceeds through a chiefly-unfolded intermediate state. We also find that the pressure-dependent NMR chemical shift changes and the residue-specific compressibility both predict which amino acid residues are near protein cavities. We demonstrate that pressure-NMR is a powerful approach for characterizing protein conformational switching and can provide unique information that is not easily accessible through other techniques. Copy rights belong to original authors. Visit the link for more info

Anthony Aramini is an online Sales expert and the founder of 2 digital consulting agencies. In this conversation, Anthony sits down and helps us look at selling in a different light while telling his life story of rags to riches. Anthony and Vic discuss new strategies that can take your revenue and income to a whole other level. Sit back and soak in a ton of sales-oriented value. Support the show (http://www.socialgravity.co)

Marc and James agree about a lot regarding the plot of the Books of the Long & Short Sun. So why do they disagree so adamantly about so much? -You can also get episodes on your podcast app or on our Youtube channel.If you have problems accessing the podcast on your favorite platform, let us know.Questions, comments, corrections, additions, alternate theories?Connect with us on Facebook...or on Twitter @rereadingwolfe...or on Instagram: rereadingwolfepodcast...or on Reddit: rereadingwolfepodcast  -Intro from "The Alligator", Annihilation soundtrack by Ben Salisbury and Geoff BarrowOutro from "The Windmills of Your Mind" by Dusty SpringfieldLogo art by SonOfWitzOutros and alternate outros are cued on the Rereading Wolfe Podcast Spotify playlist IF the songs are available on Spotify.

Oncotarget interviews Dr. Beatrice Aramini from the University of Modena and Reggio Emilia in Modena Italy about their Featured Cover Paper for Volume 11 Issue 5 titled "Overall survival in patients with lung adenocarcinoma harboring “niche” mutations: an observational study" PRESS RELEASE: The cover for issue 5 of Oncotarget features Figure 2, "Survival curves in the KRAS, EGFR, and niche mutations cohorts," by Aramini, et al. Mutations were observed in all genes studied, except c-MET, DDR2, MAP2K1, and RET. The multivariable analysis showed that: Niche mutations had higher mortality than EGFR mutations KRAS mutations had higher mortality than EGFR mutations, and Niche mutations presented similar mortality to KRAS mutations. Niche mutations exhibited an increased risk of death when compared with EGFR mutations and a similar risk of death when compared with KRAS mutations. Dr. Beatrice Aramini from the Division of Thoracic Surgery in Department of Medical and Surgical Sciences at the University of Modena and Reggio Emilia in Modena Italy said in their Oncotarget Research Paper, "In the last century, carcinoma of the lung has progressed from an uncommon and obscure disease to the most common cancer in the world, and the most common cause of death from cancer." In addition to these somatic mutations, which are the most frequent, other mutations in several genes have been discovered, including BRAF, c-MET, DDR2, HER2, MAP2K1, NRAS, PIK3CA, and RET mutations. Moreover, the prevalence of the RET mutation in adenocarcinoma was estimated to be 1.7%, and the prevalence of DDR2 mutation in lung cancer was 2.2%. With regard to treatment, discoveries of gene mutations have allowed the development of targeted therapies, which are considered more effective for survival than chemotherapy in patients with advanced mutated disease. Considering the potential aggressiveness of niche mutations in this context, the technological advances of next-generation sequencing, which is currently used in clinical practice, represents a precise approach to identifying a large panel of mutations in oncologic patients. The Armini Research Team concluded, "The correct selection of mutations will be helpful in terms of the greater efficacy of treatment in association with better prognosis and a higher quality of life for oncologic patients." Full text - https://doi.org/10.18632/oncotarget.27472 Correspondence to - Beatrice Aramini,beatrice.aramini@unimore.it Keywords - somatic mutations, non-small cell lung cancer (NSCLC), lung cancer treatment, overall survival, target therapy Sign up for free Altmetric alerts about this article About Oncotarget Oncotarget is a weekly, peer-reviewed, open-access biomedical journal covering research on all aspects of oncology. To learn more about Oncotarget, please visit http://www.oncotarget.com or connect with: YouTube - http://bit.ly/OncotargetYoutube SoundCloud - https://soundcloud.com/oncotarget Facebook - https://www.facebook.com/Oncotarget/ Twitter - https://twitter.com/oncotarget LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Oncotarget is published by Impact Journals, LLC please visit http://www.ImpactJournals.com or connect with @ImpactJrnls Media Contact 18009220957x105 MEDIA@IMPACTJOURNALS.COM

PRESS RELEASE: Overall survival in patients with lung adenocarcinoma harboring “niche” mutations: an observational study The cover for issue 5 of Oncotarget features Figure 2, "Survival curves in the KRAS, EGFR, and niche mutations cohorts," by Aramini, et al. Mutations were observed in all genes studied, except c-MET, DDR2, MAP2K1, and RET. The multivariable analysis showed that: Niche mutations had higher mortality than EGFR mutations KRAS mutations had higher mortality than EGFR mutations, and Niche mutations presented similar mortality to KRAS mutations. Niche mutations exhibited an increased risk of death when compared with EGFR mutations and a similar risk of death when compared with KRAS mutations. Dr. Beatrice Aramini from the Division of Thoracic Surgery in Department of Medical and Surgical Sciences at the University of Modena and Reggio Emilia in Modena Italy said in their Oncotarget Research Paper, "In the last century, carcinoma of the lung has progressed from an uncommon and obscure disease to the most common cancer in the world, and the most common cause of death from cancer." In addition to these somatic mutations, which are the most frequent, other mutations in several genes have been discovered, including BRAF, c-MET, DDR2, HER2, MAP2K1, NRAS, PIK3CA, and RET mutations. Moreover, the prevalence of the RET mutation in adenocarcinoma was estimated to be 1.7%, and the prevalence of DDR2 mutation in lung cancer was 2.2%. With regard to treatment, discoveries of gene mutations have allowed the development of targeted therapies, which are considered more effective for survival than chemotherapy in patients with advanced mutated disease. Considering the potential aggressiveness of niche mutations in this context, the technological advances of next-generation sequencing, which is currently used in clinical practice, represents a precise approach to identifying a large panel of mutations in oncologic patients. The Armini Research Team concluded, "The correct selection of mutations will be helpful in terms of the greater efficacy of treatment in association with better prognosis and a higher quality of life for oncologic patients." Full text - https://doi.org/10.18632/oncotarget.27472 Correspondence to - Beatrice Aramini,beatrice.aramini@unimore.it Keywords - somatic mutations, non-small cell lung cancer (NSCLC), lung cancer treatment, overall survival, target therapy Sign up for free Altmetric alerts about this article About Oncotarget Oncotarget is a weekly, peer-reviewed, open access biomedical journal covering research on all aspects of oncology. To learn more about Oncotarget, please visit http://www.oncotarget.com or connect with: YouTube - http://bit.ly/OncotargetYoutube SoundCloud - https://soundcloud.com/oncotarget Facebook - https://www.facebook.com/Oncotarget/ Twitter - https://twitter.com/oncotarget LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Oncotarget is published by Impact Journals, LLC please visit http://www.ImpactJournals.com or connect with @ImpactJrnls Media Contact 18009220957x105 MEDIA@IMPACTJOURNALS.COM

Renowned Wolfe scholar Marc Aramini returns to the show to present a very different reading about the puzzles and mysteries. Check out Marc's YouTube channel! Support the show on Patreon. You'll gain access to twenty bonus episodes and help us reach our goal of hosting an online discussion of this novel with listeners. Join the conversation on the Claytemple Forum. Up next: A conversation with Wolfe scholar Marc Aramini about the entire novel. You won't want to miss it!

Today, Anthony Aramini will bring his top marketing lessons to the table, offering actionable content you can use right away AND discussing inner game stuff as well, when he gives his take on intentionality and how that plays into your success in both business and life. www.ShatterTheMoldPodcast.com

In this episode, Cathy welcomes Heather O’Neill, the designer of Meeple Party, to the co-host seat and they talk about the games they’ve played recently including Azul, Kingdom Builder, Patchwork Express, and Terraforming Mars: Colonies; and Cathy interviews Steven Aramini about his new game, Animal Kingdoms.

Zach sits down with game designer Steve Aramini to learn all about the development of the award winning game Animal Kingdoms from Galactic Raptor Games.

Ryan and I chat with Carla Kopp and Dan Letzring of Galactic Raptor about their first game, Animal Kingdoms. You've probably seen the gorgeous art for the game on Twitter or Facebook and now you can find out more about it and the game.

How to get high-end clients using Facebook organically! w/ Anthony Aramini #SMC #ArneGiske #Course The Sell More Courses Podcast aims to inspire young people to live the life they want to live, via entrepreneurship. Arne's mission is to inspire, empower, and educate the next generation of business leaders through the power of storytelling and teaching through online courses. Wanna Learn How To Pull Off Consistent 5 Figure Online Course Promotions Using The “Evergreen Launch Method”? Check out Courselaunchprofits.com

Renowned Wolfe scholar Marc Aramini returns to the show to talk about the novella The Fifth Head of Cerberus. Check out Marc's YouTube channel! Support the show and help us release episodes more frequently by becoming a patron on Patreon. Up next: "A Story," by John V. Marsch, the next novella in The Fifth Head of Cerberus. To start, we're reading pages 85-90.

Steven and I discuss his newest game, Tricky Tides. It's a cool little pick up and deliver game with some neat movement mechanics. We also talk about his up coming Button Shy game, Sprawlopolis.

If you like bits and tangents, then oh boy, this is the episode for you! We're talking U2, Lawry's Seasoned Salt, horses, and the animated TV show Centurions. Plus somehow, we manage to make time to talk about the 2018 game Barker's Row from Overworld Games and designed by Steven Aramini.

Glenn and Brandon are thrilled to bring you their conversation with Marc Aramini about Operation ARES and Wolfe's early career. Get your potato chips, because it's an exciting one!   Join the conversation on the Claytemple Forum.   To support the show, gain access to exclusive bonus episodes, and to help us reach our goal of bringing you an episode every week, please become a patron on Patreon.   Grab a copy of Marc's excellent book Between Light and Shadow.   Up next: The Blue Mouse, which you can read in Castle of Days.