Podcasts about nmr

In Episode 196 of the Fit Mother Project Podcast, Dr. Anthony Balduzzi sits down with board-certified cardiac surgeon Dr. Philip Ovadia for a deep, myth-busting conversation on the real root causes of heart disease.Dr. Ovadia has operated on thousands of patients, transformed his own health by losing nearly 100 pounds, and now dedicates his work to keeping people off the operating table entirely.Together, they challenge decades of conventional medical thinking around cholesterol, statins, and dietary fat, and replace it with a clearer, more empowering framework built around insulin resistance and inflammation.Dr. Ovadia shares the five key steps to reversing insulin resistance, the five basic metabolic markers everyone should know, what advanced lipid testing can reveal that a standard panel misses, and how to build a diet centered on whole, real food. He also explains where statins genuinely help, where they fall short, and why the standard American approach to heart disease prevention simply has not worked. If you want to understand what is actually driving heart disease — and what you can do about it starting today — this conversation delivers both the science and the practical tools to take action.Rate & Review - If this episode encouraged you, please rate and review the Fit Mother Project Podcast. Your support helps more women over 40 find empowering, practical guidance for building lifelong health and strength.Join the Fit Mother Community - If you want support putting these ideas into practice, come join the Fit Mother community. We are here to help you build strength, confidence, energy, and sustainable health in every season of life. Fit Mother ProjectKey Takeaways:The real root causes of heart disease: inflammation and insulin resistanceWhy 50 years of focusing on cholesterol has not reduced heart diseaseHow plaque builds up and what actually triggers itDietary cholesterol vs. blood cholesterol (what the difference means for you)Lipoproteins explained: HDL, LDL, VLDL and why not all are harmfulWhy LDL cholesterol is only half the storyLarge fluffy vs. small dense LDL particles (why particle quality matters more than quantity)88–93% of American adults have some degree of insulin resistanceThe five-step plan to reverse insulin resistanceWhole real food as the foundation of a heart-healthy dietHow carbohydrate reduction supports metabolic healthCarbohydrate targets: under 20g for diabetics, up to 100g for insulin-sensitive individualsWhy keto and carnivore diets can be heart-healthy approachesThe role of muscle mass in protecting against insulin resistanceSleep as an underrated pillar of metabolic healthWhole fruit, fiber, and polyphenols (how to include them wisely)The five basic metabolic health markers you can measure yourselfWaist circumference targets: under 40 inches for men, under 35 inches for womenBlood pressure, fasting glucose, triglycerides, and HDL targets explainedHow to know if you are insulin resistant before your doctor tells youAdvanced lipid panels and NMR testing (what to ask for and why)When statins help — and when they offer no benefit at allPCSK9 inhibitors and the evidence for metabolically healthy patientsRed meat as a nutrient-dense, bioavailable foundation foodDr. Ovadia's personal journey: from morbidly obese cardiac surgeon to optimal health at 52Patient empowerment — why your health should not be outsourced to the healthcare systemOverview of Stay Off My Kitchen Table — Dr. Ovadia's new bookWant To Change Your Life? Check Out Foundations!Foundations is a simple, sustainable, and specific weight loss program designed especially for busy women over 40. With short metabolic training workouts, an easy-to-follow meal plan, and an accountability team there for you every step of the way, Foundations can help you lose weight, regain energy and vitality, and live life to the fullest. Click here to see everything you get when you join Foundations. Subscribe to our YouTube Channel and check out our blog, and follow us on Instagram, TikTok, Facebook, Twitter, LinkedIn, and Threads.*Please know that weight loss results and health changes/improvements vary individually; you may not achieve similar results. Always consult with your doctor before making health decisions. This is not medical advice. This is simply very well-researched information on longevity training, muscle health, and healthy aging.

Magnus Söderman var chefsideolog och talesperson för terrorstämplade nynazistiska Nordiska Motståndsrörelsen (NMR) fram till 2010. Sedan dess har han varit aktiv i både rörelser och gett ut böcker med nynazistisk och rasideologisk prägel. OBS. Hela avsnittet är 3 tim 22 min långt. Vill du få tillgång till alla hela avsnitt? Bli medlem på Sista Måltiden. Som medlem får du tillgång till alla nya och gamla avsnitt i sin helhet och utan reklam. Lyssna i valfri podcast-app, inklusive Spotify. Enkelt att komma igång. Ingen bindningstid. Tryck här för att bli medlem eller gå in på https://sistamaltiden.se. Hosted on Acast. See acast.com/privacy for more information.

Magnus Söderman var chefsideolog och talesperson för terrorstämplade nynazistiska Nordiska Motståndsrörelsen (NMR) fram till 2010. Sedan dess har han varit aktiv i både rörelser och gett ut böcker med nynazistisk och rasideologisk prägel. OBS. Hela avsnittet är 3 tim 22 min långt. Vill du få tillgång till alla hela avsnitt? Bli medlem på Sista Måltiden. Som medlem får du tillgång till alla nya och gamla avsnitt i sin helhet och utan reklam. Lyssna i valfri podcast-app, inklusive Spotify. Enkelt att komma igång. Ingen bindningstid. Tryck här för att bli medlem eller gå in på https://sistamaltiden.se. Hosted on Acast. See acast.com/privacy for more information.

In this episode of the Fit Father Project Podcast, Dr. Anthony Balduzzi sits down with cardiac surgeon Dr. Philip Ovadia for a deep dive into the nutritional side of heart disease.Dr. Ovadia shares how his own journey from morbid obesity and pre-diabetes to optimal health at 52 completely transformed his approach to medicine, and why he now dedicates his life to keeping people off his operating table.Together, they dismantle decades of conventional wisdom around cholesterol, statins, and dietary fat, and reframe heart disease prevention around its true root causes: inflammation and insulin resistance. Dr. Ovadia explains how atherosclerotic plaque actually forms, why LDL cholesterol is far more nuanced than most doctors acknowledge, and exactly which tests you should be requesting to get a real picture of your metabolic health.He also walks through his top five strategies to reverse insulin resistance, specific carbohydrate targets for different individuals, why red meat may be the most nutrient-dense food a human can eat, and how intermittent fasting fits into a heart-healthy lifestyle.If you want to understand what truly drives heart disease and what you can do about it through food and lifestyle, this episode is essential listening.It is also a great one to share with anyone who has been told their cholesterol is too high or has a family history of heart disease.Rate & Review — If this episode helped you see heart health and nutrition in a new light, please take a minute to rate and review the Fit Father Project Podcast.Your review helps more men discover the show and get the tools they need to live stronger, healthier, and longer.Join the Fit Father Community — Want support from other men working to get stronger, leaner, and healthier after 40?Join the Fit Father Project and surround yourself with people who are committed to living with more strength, energy, and purpose.Key Takeawayswhat actually causes heart diseaseatherosclerotic plaque formation explainedwhy cholesterol alone is not the root causeinflammation and insulin resistance as the true driversdietary cholesterol vs. blood cholesterolHDL, LDL, and VLDL differences explainedlipoproteins and why particle quality matterslarge fluffy vs. small dense LDL particleswhy statins fall short for metabolically healthy peoplePCSK9 inhibitors and the metabolic health nuancefive strategies to reverse insulin resistancewhole real food as the non-negotiable foundationreducing carbohydrates for insulin resistancemuscle building as metabolic protectionsleep and its direct impact on insulin sensitivityberries and whole fruit in the right contextketo and carnivore as legitimate heart-healthy approachescarb targets based on your metabolic statusfive accessible tests to assess insulin resistancewaist circumference guidelines for men and womenblood pressure targets without medicationfasting blood glucose and what the numbers meantriglycerides and HDL as key metabolic markersadvanced lipid panel and NMR testing explainedhow to ask your doctor for better, more actionable labspatient empowerment in a changing medical landscapered meat as the most nutrient-dense foodanimal protein as the dietary foundationnutrient density and bioavailability compared across foodsanti-nutrients in plant foods and who they affectintermittent fasting benefits for heart and metabolic healthDr. Ovadia's simple daily meals and eating approachvegetables, oxalates, and gut health considerationsoverview of Stay Off My Kitchen TableWant To Change Your Life? Check Out Foundations!Foundations is a simple, sustainable, and specific weight loss program designed especially for busy men over 40.With short metabolic training workouts, an easy-to-follow meal plan, and an accountability team there for you every step of the way, Foundations can help you lose weight, regain energy and vitality, and live life to the fullest.Click here to see everything you get when you join Foundations, subscribe to our YouTube Channel, check out our blog, and follow us on Instagram, TikTok, Facebook, Twitter, LinkedIn, and Threads.Please know that weight loss results and health changes/improvements vary individually; you may not achieve similar results. Always consult with your doctor before making health decisions. This is not medical advice — simply very well-researched information on heart disease, cholesterol, insulin resistance, and nutritional strategies for cardiovascular health.

Millions of people leave their doctor's office with "normal" bloodwork — and still feel terrible. Fatigued, foggy, anxious, in pain. If that's you, Dr. Terri has a message: your labs aren't lying, but the reference ranges might be. In this solo episode, Dr. Terri breaks down exactly why the standard of care is failing patients, how clinical reference ranges have quietly shifted to accommodate a sicker and sicker population, and what comprehensive, preventative testing actually looks like — including a full list of labs you can bring to your next appointment. If you've been dismissed, minimized, or told to just get older gracefully — this one is for you. Labs Dr. Terri recommends asking your provider for: Thyroid TSH (Thyroid Stimulating Hormone) Free T3 Free T4 Reverse T3 TPO Antibodies (Thyroid Peroxidase) Hormones Testosterone (men and women) Estrogen DHEA FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) Progesterone (especially if dealing with infertility or irregular cycles) 4–5 Point Salivary Cortisol Panel Metabolic Fasting Insulin (optimal: 9–12) Hemoglobin A1C Full Lipid Panel with particle size and ApoLipoprotein analysis (NMR panel or Cleveland Clinic panel recommended) CRP (C-Reactive Protein) — inflammatory marker Nutrients Vitamin D (optimal: 60–100) Vitamin B12 (optimal: 800+) Ferritin / Iron stores (optimal: 70–150) RBC Magnesium (red blood cell level — not serum) Omega-3 Index (omega-3 to omega-6 ratio) Gut GI Map Test Your symptoms are real. Your body is sending a signal. Dr. Terri gives you the roadmap to finally get the answers you deserve. For a deeper dive into Thyroid, check out this episode with Dr. Johnny Peet -https://www.youtube.com/watch?v=T1ITw0lMwwk Episode Chapters: 00:00 — Introduction 07:01 — Why Patients Are Told "Everything Is Normal" 10:35 — Why "Normal" and Optimal Are Not the Same Thing 13:38 — The Tests Your Doctor Should Be Running (But Probably Isn't) 22:01 — Cholesterol, Statins, and the Metabolic Markers That Actually Matter 26:11 — Nutrient Deficiencies, Gut Health & Sleep as Root Cause Drivers 30:31 — Practical Next Steps: Labs to Request, Providers to Seek -- The Dr. Terri Show is presented by Evexias Health Solutions. For more, visit: https://www.evexias.com ---------------------------------------------------------------- Connect with Dr. Terri DeNeui, DNP:

In this episode, Dr Matthew Gubens and Dr Helena Yu discuss the evolving role of TROP2-directed therapies in non-small-cell lung cancer, with a focus on how antibody–drug conjugates (ADCs) fit into current treatment strategies, including The mechanism of action and clinical trial outcomes of TROP2-directed ADCs like datopotamab deruxtecan and sacituzumab tirumotecan Use of these therapies in EGFR-mutant disease and how they fit into a changing treatment landscape Practical advice on associated adverse events and additional considerations, A look at future directions on the horizon, such as first-line studies and predictive biomarkers Get access to all of our new podcasts by subscribing to the Decera Clinical Education Oncology Podcast on Apple Podcasts, YouTube Music, or Spotify. Presenters: Matthew Gubens, MD, MS, FASCO​ Medical Director, Thoracic Medical Oncology​ University of California, San Francisco​ San Francisco, California Helena Yu, MD​ Professor of Medicine​ Thoracic Oncology Service​ Memorial Sloan Kettering Cancer Center​ New York, New York Link to full program:https://bit.ly/41vAnfH Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

När vi på Expo publicerade granskningen "I ministerns närhet" visade vi att en nära anhörig till en minister i Sveriges regering under en längre tid varit aktiv i den våldsbejakande högerextrema miljön. Det handlade om en person som rekryterar till vit makt-miljöer, samarbetar med NMR-aktivister och rör sig i nätverk som Säkerhetspolisen varnar för. Vi kunde också visa att det här enligt en säkerhetsexpert utgör en säkerhetsrisk – och att Säpo enligt våra uppgifter inte haft kännedom om det. Granskningen har fått stor uppmärksamhet och nu också belönats med en Guldspade. Men som så ofta när vi gör den här typen av avslöjanden så uppstår nästa fråga ganska snabbt: Vad blev det egentligen av det här? Gäst i studion är Erik Glaad, reporter på Expo. Programledare: Anna Fröjd   Ställ en fråga till oss! Skicka in din lyssnarfråga som ett röstmeddelande till oss: https://www.speakpipe.com/studioexpo Vill du hellre mejla så skicka din fråga till studioexpo@expo.se    Läs mer: I ministerns närhet (Erik Glaad, Jonathan Leman 2025): https://expo.se/fordjupning/i-ministerns-narhet/ Studio Expo: Så jobbde vi med granskningen (2025): https://expo.se/podcasts/fallet-forssell/ Daniel Poohl: Historien om ministerns anhöriga är en säkerhetsfråga (2025): https://expo.se/kommentar/historien-om-ministerns-nara-anhoriga-ar-en-sakerhetsfraga/   Expo behöver ditt stöd Bli poddvän här: https://expo.se/stod-expo/bli-poddvan/  Prenumerera på Expo: https://expo.se/tidskriften/prenumerera  --- Studio Expo ger dig som lyssnar fördjupningar om våra avslöjanden, mer om våra granskningar och analyser av högextrema tendenser. Varje vecka i din poddspelare! Expo är en religiöst och partipolitiskt obunden stiftelse. Vi har granskat och bevakat extremhögern sedan 1995 – för en levande demokrati där rasistiska idéer och organisationer saknar inflytande. Stöd vår verksamhet genom att bli månadsgivare eller swisha en slant till 123 271 02 59.

Fanny Wijk och Kalle Berg pratar om Sveriges bragdmatch igår och om ett nytt lagförslag som skulle kunna stänga Liseberg. De pratar också om att Valter Nilsson pissar på reklambranschen och att Trumps enorma balsalsbygge stoppas.Dessutom: Svenska i nya White Lotus, misstänkt medlemskupp i Liberalerna och NMR-ledare får inte hjälp med bostad. Hosted on Acast. See acast.com/privacy for more information.

Join us as Declan and Roger discuss the evidence for routine table tilt during elective caesarean section.   Has this changed your practice? What is your opinion on this topic? We'd love to read your emails.  As mentioned in the episode we would love to do a future episode on Q&A so if you have any questions on any topic you would like us to tackle please send them in! Send your comments / questions to: obsgynaecritcare@gmail.com References Hughes EJ, Price AN, McCabe L, Hiscocks S, Waite L, Green E, Hutter J, Pegoretti K, Cordero‐Grande L, Edwards AD, Hajnal JV. The effect of maternal position on venous return for pregnant women during MRI. NMR in Biomedicine. 2021 Apr;34(4):e4475.  Couper S, Clark A, Thompson JM, Flouri D, Aughwane R, David AL, Melbourne A, Mirjalili A, Stone PR. The effects of maternal position, in late gestation pregnancy, on placental blood flow and oxygenation: an MRI study. The Journal of physiology. 2021 Mar;599(6):1901-15.  Higuchi H, Takagi S, Zhang K, Furui I, Ozaki M. Effect of lateral tilt angle on the volume of the abdominal aorta and inferior vena cava in pregnant and nonpregnant women determined by magnetic resonance imaging. Anesthesiology. 2015;122(2):286-293.  Fujita N, Higuchi H, Sakuma S, Takagi S, Latif MA, Ozaki M. Effect of right-lateral versus left-lateral tilt position on compression of the inferior vena cava in pregnant women determined by magnetic resonance imaging. Anesthesia & Analgesia. 2019 Jun 1;128(6):1217-22.  Aust H, Koehler S, Kuehnert M, Werdehausen R, Schleppers A, Reese PC, Reyher C. Guideline-recommended 15° left lateral table tilt during cesarean section in regional anesthesia—practical aspects: an observational study. Int J Obstet Anesth. 2016 Aug;27:47-53.  Crawford JS, Burton M, Davies P. Time and lateral tilt at Caesarean section. Br J Anaesth. 1972 May;44(5):477-84.  Lee AJ, Landau R, Mattingly JL, Meenan MM, Corradini B, Wang S, Goodman SR, Smiley RM. Left lateral table tilt for elective cesarean delivery under spinal anesthesia has no effect on neonatal acid–base status: a randomized controlled trial. Anesthesiology. 2017;127(2):241‑249.  Jackson KL, Smiley RM, Lee AJ. Neonatal acid-base status before and after discontinuing routine left uterine displacement for elective cesarean delivery: a retrospective cohort study (2014–2017). Int J Obstet Anesth. 2025;62:104350.  You need to add a widget, row, or prebuilt layout before you’ll see anything here.

What if the person who transformed your entire career is also someone you haven't spoken to in seven years? In this episode, Ryan Ellefsen shares how he helps businesses take credit cards, lower processing fees, and protect their revenue as VP of EasyPay Direct, a merchant services company he recently joined after 20 years in the industry. EasyPay serves coaches, consultants, speakers, and internet marketers,  processing payments for names like Tony Robbins, Grant Cardone, and Frank Kern across 34 US locations. Ryan built his career expertise under the mentorship of Steve Thorne, CEO of NMR (National Marketing Resources), eventually rising from Processing Manager to VP and co-building what became Platinum Payment Systems. Today, Ryan is known for his transparent, relationship-first approach to merchant services — always insisting on a face-to-face conversation before onboarding any client, no matter how small. Ryan honors Steve Thorne, the man who hired him at $70,000/year when he was making $23,400 as a Spanish teacher in Utah. Phil Smith introduced Ryan to Steve while both were in an MBA program, and Steve believed in Ryan enough to bring him into NMR, where Ryan spent 10 transformative years climbing from Processing Manager all the way to VP. Under Steve's roof, Ryan co-built a merchant processing company that eventually merged into Platinum Payment Systems.   [00:03:41] Reconnected Through a Mutual Friend Kevin and Ryan originally met years ago at Genius Network Recently reconnected via mutual friend Anthony Simon through an email introduction Neither realized in the intro email that they already knew each other [00:03:51] VP of EasyPay Direct: What He Does and Who He Serves Merchant services company helping businesses accept credit cards and get funding Specializes in the coach, consultant, speaker, author, and internet marketing space Serves major names like Tony Robbins, Grant Cardone, and Frank Kern Recently joined after 20 years in the industry; he and CEO Brad Weimert were friendly competitors for two decades [00:05:04] EasyPay vs. PayPal: The Key Difference PayPal is better for card-present transactions like retail stores EasyPay specializes in card-not-present, high-risk: coaching, big-ticket packages, phone sales High-risk means future fulfillment over time, high-ticket pricing, sold over the phone Premier company in the country for internet marketing and coaching businesses [00:07:55] What Inspires Ryan Most: Giving People a Fair Deal Has an affinity for the person being ripped off by hidden fees Philosophy: everybody can win — a 10-year relationship beats a 6-month windfall Sometimes helps small businesses where he makes almost nothing — and loves it Tries to learn something from every single conversation [00:13:02] How EasyPay Lowers Your Rates Over Time EasyPay has its own gateway to manage multiple banks from a single login Uses Level 3 Advantage and tokenization to lower interchange rates Can lower interchange by up to 75 basis points (0.75%) EasyPay's margin stays fixed; all savings go directly to the client [00:18:40] The Industry's Dirty Secret: Watch Your Statements Processors can legally raise your rates by burying notice in statement fine print Not calling to cancel is considered acceptance of new terms They raise rates 5 –10 basis points at a time. Visa changes rates every six months and they go up more often than down [00:26:15] Started as a Spanish Teacher Making $23,400 a Year Graduated college, went on a church mission to South America from 1991 to 1993 Came back, majored in Spanish teaching, played sports, had fun First teaching job in Utah in 1997 paid $23,400/year Started a carpet cleaning business in school that eventually made 10x his teaching salary [00:28:00] Phil Smith Introduces Ryan to Steve Thorne Met Phil Smith in his MBA cohort Phil introduced him to Steve Thorne, CEO of NMR (National Marketing Resources) in Kearney, Missouri Steve hired Ryan as Processing Manager at $70,000/year nearly triple his teaching salary His bonus in year two was bigger than his entire teaching salary [00:29:05] Ten Years at NMR: From Manager to VP Progressed from Processing Manager → Director → Managing Director → VP NMR and sister company PMI did infomercial production for Dean Graziosi, Anthony Morrison, and others Did hundreds of millions in coaching and big-ticket event sales Ryan pitched starting a merchant processing company; Steve challenged him to make it a million-dollar idea. [00:30:31] When a Great Relationship Fractures Ryan and Steve haven't spoken in seven years following a lawsuit Ended in a no-fault settlement — neither side got what they wanted Ryan still considers Steve one of the best, most honest people he's ever met "If he ever catches wind of this podcast… I would welcome that" [00:35:20] What Steve's Mentorship Still Looks Like Today After the split, became VP of a digital marketing company within 6 months Core lesson from Steve: how to treat people with genuine sincerity "Nobody who's ever met Steve Thorn dislikes Steve Thorn" Attributes his versatility and confidence across industries entirely to Steve's tutelage   KEY QUOTES "My philosophy is that everybody can win. If you can set up a relationship that makes some money for the next 10 years, that's way better than a relationship that makes you a whole bunch of money for six months." - Ryan Ellefsen "Steve Thorn transformed my life. If he hadn't given me that opportunity, I wouldn't be where I am today and I wouldn't have what I have today." - Ryan Ellefsen "Nobody who's ever met Steve Thorn dislikes Steve Thorn. He's sincere. He's a good guy and he just knows how to treat people. And so I learned a lot from him in that regard." - Ryan Ellefsen CONNECT WITH RYAN ELLEFSEN

MRIs are loud. They're huge. They're magnetic. But what are they actually doing? This week, we bring Claire back to help us connect the dots between NMR (yes, organic chem flashbacks) and MRI. How does a technique built on tiny hydrogen protons turn into a 3D image of your brain? How can it tell the difference between tissue and fluid? Why can't you bring metal anywhere near the machine? We ask: • What are your protons doing inside an MRI? • How does “magnetic resonance” become an image? • Why does oxygenated blood matter? • And how did anyone figure this out in the first place? If you've ever had an MRI, or just wondered how we can see inside the body without radiation or surgery, this episode pulls back the curtain. Listen in and rethink what's happening inside that giant magnet. 00:00 MRI Episode Kickoff 01:11 Meet Claire Again 02:27 PhD Candidate Explained 03:44 NMR Basics Begin 04:33 Protons And Magnets 06:46 RF Pulse And Signal 11:16 Hydrogen Everywhere 13:35 Reading NMR Peaks 16:02 Matrix And Practice 18:31 Jam Summarizes NMR 20:44 Why MRI Not NMR 22:45 Spin And Isotopes 29:02 MRI Uses Body Water 30:37 Tissue Contrast And T1 33:38 Resolution Limits 34:25 MRI Resolution Limits 35:34 From NMR to Images 36:50 K Space and Gradients 41:30 Voxels and 3D Views 44:05 Contrast and Clinical Uses 49:47 Research Possibilities 51:11 Functional MRI Explained 56:14 MRI Safety and Magnet Strength 58:00 Helium and Heavy Machines 01:02:43 Science Boundaries and Wrap Up   Support this podcast on Patreon Buy Podcast Merch and Apparel Check out our website at chemforyourlife.com Watch our episodes on YouTube Find us on Instagram, Twitter, and Facebook @ChemForYourLife References from the Episode: Thanks to our monthly supporters Amanda Raymond Emily Morrison Kyle McCray Justine Emily Hardy Ash Vince W Julie S. Heather Ragusa Autoclave Dorien VD Scott Beyer Jessie Reder J0HNTR0Y Jeannette Napoleon Cullyn R Erica Bee Elizabeth P Rachel Reina Letila Katrina Barnum-Huckins Suzanne Phillips Venus Rebholz Jacob Taber Brian Kimball Kristina Gotfredsen Timothy Parker Steven Boyles Chris Skupien Chelsea B Avishai Barnoy Hunter Reardon Support this podcast on Patreon Buy Podcast Merch and Apparel Check out our website at chemforyourlife.com Watch our episodes on YouTube Find us on Instagram, Twitter, and Facebook @ChemForYourLife Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Witam Państwa, nazywam się Jarosław Drożdż, pracuję w Centralnym Szpitalu Klinicznym Uniwersytetu Medycznego w Łodzi, skąd nagrywam podcast Kardio Know-How. W tym odcinku omawiam efekty połączenia leków hamujących krzepnięcie krwi.Po zawale ściany przedniej skrzeplina w lewej komorze występuje obecnie u 9–12% chorych (a w NMR nawet u ponad 16%), podczas gdy w erze przedtrombolitycznej sięgała 60%. Rezonans magnetyczny wykrywa skrzepliny nawet czterokrotnie częściej niż echo, a tylko około 1/3 zmian widoczna jest w badaniu echokardiograficznym. Link do pełnej wersji artykułu state of the art z roku 2022: https://www.jacc.org/doi/10.1016/j.jacc.2022.01.011Ticagrelor zmniejsza częstość skrzeplin względem klopidogrelu, dlatego pozostaje preferowanym składnikiem DAPT. W badaniu APERITIF opublikowanym 25 lutego 2026 w JAMA Cardiology oceniono dodanie naczyniowej dawki riwaroksabanu (2 × 2,5 mg) do DAPT po zawale ściany przedniej.https://jamanetwork.com/journals/jamacardiology/fullarticle/2845590W nowej analizie (ok. 560 pacjentów) redukcja skrzeplin była niewielka i statystycznie nieistotna (poniżej 14% vs >16%), przy większej liczbie głównie drobnych krwawień (BARC 1). Mimo częstego występowania skrzeplin zdarzenia zatorowe były rzadkie (ok. 1–1,5%), a śmiertelność poniżej 1%. W praktyce oznacza to, że rutynowe NMR ani dodawanie riwaroksabanu do DAPT z ticagrelorem tuż po zawale nie wydają się uzasadnione, a kluczowe pozostaje stosowanie skutecznej DAPT.Szczegółowy TRANSKRYPT do odcinka.Podcast jest przeznaczony wyłącznie dla osób z profesjonalnym wykształceniem medycznym.

Understanding and Managing Heart Health: In this Heart Health Month episode of the Intelligent Medicine Podcast, nutritionist Leyla Muedin addresses a listener's question about elevated cholesterol levels and calcium scores. Drawing on an article written by Dr. Hoffman, she emphasizes the importance of discussing statin use with a doctor, considering individual risk factors, and getting additional tests like VAPs, NMR, homocysteine, and lipoprotein levels. The episode explores the importance of vitamins K2 and folate in cardiovascular health, addressing nutritional deficiencies, and the impact of dietary choices on heart health.

In this episode of The Food Professor Podcast, hosts Michael LeBlanc and Dr. Sylvain Charlebois unpack two powerful and timely themes shaping Canada's food system: the shifting geopolitical landscape of agri-food and the growing threat of food fraud. The episode opens with a wide-ranging news segment focused on Canada's evolving trade relationship with China, recent developments at Davos, and new data on food inflation.Sylvain shares insights from Manitoba Ag Days, where optimism is building among farmers following Canada's short-term agricultural trade deal with China, particularly for canola, lobster, and beef exports. The hosts explore the strategic implications of re-opening Chinese markets, noting how geopolitical uncertainty is now a permanent feature of food systems. Sylvain argues that Canada must invest more heavily in domestic manufacturing, modernize supply management, and incentivize green technologies to strengthen long-term food sovereignty. The conversation also turns to food inflation, with Sylvain explaining why Canada's 6.2% food inflation rate cannot be blamed solely on the GST holiday, pointing instead to opportunistic pricing and structural inefficiencies across the supply chain.The second half of the episode features a compelling interview with Deleo de Leonardis, CEO and Co-Founder of Purity IQ, a science-based company specializing in food and supplement authenticity testing. Drawing on her 30-year career in grocery retail, including two decades at Sobeys, Deleo explains how food fraud represents one of the most underestimated risks in modern retail. While many companies rely on basic identity testing, Deleo highlights the critical difference between identity and authenticity: a product may technically meet regulatory standards while still being diluted, substituted, or adulterated.Deleo introduces advanced tools such as nuclear magnetic resonance (NMR) spectroscopy and DNA-based testing, which allow for non-targeted analysis at the molecular level. This approach enables Purity IQ to detect unknown adulterants and inconsistencies across batches—something traditional testing methods often miss. She outlines high-risk categories such as olive oil, honey, fish, avocado oil, sesame oil, and dietary supplements, emphasizing that food fraud is an opportunistic crime driven by global supply shocks, climate events, tariffs, and geopolitical instability.Together, the episode paints a sobering picture: as supply chains become more complex and economic pressures rise, food authenticity will become a defining issue for retailers, brands, and regulators alike. The hosts conclude that in an era of shrinking trust and rising prices, transparency and scientific verification may be the only sustainable path forward for the global food industry. About UsDr. Sylvain Charlebois is a Visiting Professor in Food Policy and Distribution at McGill University and a Professor in Food Distribution and Policy in the Faculty of Management at Dalhousie University in Halifax. He is also the Senior Director of the Agri-food Analytics Lab, also located at Dalhousie University.Known as “The Food Professor”, his current research interest lies in the broad area of food distribution, security and safety. He is one of the world's most cited scholars in food supply chain management, food value chains and traceability with over 775 published peer-reviewed journal articles. Dr. Charlebois is also an editor for the prestigious Trends in Food Science Technology journal. He co-hosts The Food Professor podcast, discussing issues in the food, foodservice, grocery and restaurant industries and which is the most listened Canadian management podcast in Canada. Every year since 2012, he has published the now highly anticipated Canadian Food Price Report, which provides an overview of food price trends for the coming year. Furthermore, his research has been featured in several newspapers and media groups, nationally as well as internationally. He has testified on several occasions before parliamentary committees on food policy-related issues as an expert witness. He has been asked to act as an advisor on food and agricultural policies in many Canadian provinces and other countries.With extensive experience collaborating with businesses, governments, and NGOs, Dr. Charlebois combines academic rigor with practical expertise, making him one of the most influential voices in the global agri-food landscape. His work continues to advance the understanding of food systems, fostering innovation and resilience in a rapidly evolving industry. In 2025, he received the prestigious Charles III medal recognizing his tremendous work in informing Canadians about food issues. Michael LeBlanc is a senior retail advisor, keynote speaker and media entrepreneur. Michael has delivered keynotes, hosted fire-side discussions hosted senior retail executive on-stage in 1:1 interviews worldwide. Michael produces and hosts a network of leading retail trade podcasts, including The Remarkable Retail Podcast, The Voice of Retail, The Food Professor, The FEED powered by Loblaw and the Global eCommerce Leaders podcast. He has been recognized by the National Retail Federation (NRF) as a global Top Retail Voice for 2025 and 2025, and continues to be a ReThink Retail Top Retail Expert for the fifth year in a row.

Förra helgen samlades högerextremister återigen för den så kallade Salemmarschen söder om Stockholm. Det var 25 år sedan som den 17-åriga skinnskallen Daniel Wretström mördades och nu, 15 år efter att den ursprungliga marschen lades ned, försöker nazistiska Nordiska motståndsrörelsen mobilisera genom att rida på en våg av nostalgi och minnen från när marschen lockade som flest. Försöket blev en besvikelse för arrangörerna och från scenen frågade sig en av talarna var alla nationella var och varför de inte tagit sig till Salem. Tog sig NMR vatten över huvudet när de trodde att en ny Salemmarsch skulle ena rörelsen? Hur väl fungerar det blame game som vi nu ser från besvikna aktivister? Och ska vi betrakta Salem som en tillfällig come back eller kommer de försöka igen? Gäster i studion är Expos researcher och utbildare Morgan Finnsiö och reporter Anders Dalsbro. Programledare: Anna Fröjd Skicka in din lyssnarfråga som ett röstmeddelande till oss: https://www.speakpipe.com/studioexpo Vill du hellre mejla så skicka din fråga till studioexpo@expo.se  Läs mer: Nya Salemmarschen lockade färre än någonsin (Dalsbro, Finnsiö, Leman 2025): https://expo.se/nyhet/nya-salemmarschen-lockade-farre-an-nagonsin/ 2000 – Mordet, marschen, martyrskapet (Dalsbro, 2003): https://expo.se/nyhet/2000-mordet-marschen-martyrskapet/ Expo guidar: Extremhögerns martyrer (Dunell, 2025): https://expo.se/guide/expo-guidar-extremhogerns-martyrer/ Expo guidar: Så kallad svenskfientlighet (Dunell, 2025): https://expo.se/guide/expo-guidar-sa-kallad-svenskfientlighet/ Expo guidar: Den nazistiska kalenderns högtidsdagar (Dalsbro, 2025): https://expo.se/guide/expo-guidar-den-nazistiska-kalenderns-hogtidsdagar/   Expo behöver ditt stöd Bli poddvän här: https://expo.se/stod-expo/bli-poddvan/  Prenumerera på Expo: https://expo.se/tidskriften/prenumerera  --- Studio Expo ger dig som lyssnar fördjupningar om våra avslöjanden, mer om våra granskningar och analyser av högextrema tendenser. Varje vecka i din poddspelare! Expo är en religiöst och partipolitiskt obunden stiftelse. Vi har granskat och bevakat extremhögern sedan 1995 – för en levande demokrati där rasistiska idéer och organisationer saknar inflytande. Stöd vår verksamhet genom att bli månadsgivare eller swisha en slant till 123 271 02 59.

Witam Państwa, nazywam się Jarosław Drożdż, pracuję w Centralnym Szpitalu Klinicznym Uniwersytetu Medycznego w Łodzi, skąd nagrywam podcast Kardio Know-How. W tym odcinku omawiam pojęcie SMuRFs-less. Coraz więcej pojawia się skrótów opisujących szczególne fenotypy choroby niedokrwiennej serca, począwszy od MINOCA i INOCA, a także ANOCA, które omawiałem szerzej w odcinku 117 z 12 maja 2023 roku: https://open.spotify.com/episode/37HPbmamx5qiDVN8fUdhth?si=881fb4ec4a9143cb. Niedługo potem, 24 maja 2023 roku, w podcaście Heart ukazała się rozmowa na ten temat, choć bez użycia terminu ANOCA, lecz z rzetelnym omówieniem MINOCA i INOCA: https://open.spotify.com/episode/57BS26FP3UGH0vnb18xasn?si=4e763c576cde47bf. Dziś jednak do słownika dołącza kolejny ważny skrót – SMuRFs-less – określający pacjentów z zawałem serca i ze zwężeniami tętnic wieńcowych, ale pozbawionych klasycznych, modyfikowalnych czynników ryzyka, co opisano po raz pierwszy w JACC we 09/2023: https://www.jacc.org/doi/10.1016/j.jacc.2023.06.045. Rok później ukazała się analiza NMR pacjentów po zawale, w której po raz pierwszy pojawiło się samo pojęcie SMuRFs-less: https://www.ejinme.com/article/S0953-6205(23)00297-2/fulltext. Ogromny rezonans wywołał także znakomity tekst Paula Ridkera „SMuRF-less but inflamed”, opublikowany podczas Kongresu ESC, który jednoznacznie łączy zawał bez czynników ryzyka ze stanem zapalnym i podkreśla znaczenie hsCRP: https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehaf658/8242429?redirectedFrom=fulltext. Problem SMuRFs-less okazał się klinicznie doniosły – obejmuje ok. 11% wszystkich pacjentów z OZW i ponad 20% chorych ze STEMI, co w Polsce w 2024 roku przełożyło się na ok. 11 tysięcy takich przypadków, zgodnie z danymi z naszej publikacji w Polish Heart Journal: https://journals.viamedica.pl/polish_heart_journal/article/view/108435. Pacjenci ci mają wyższe ryzyko wczesnej śmiertelności, częściej doświadczają zatrzymania krążenia, wstrząsu kardiogennego i powikłań okołozabiegowych, a jednocześnie częściej brakuje u nich tradycyjnych czynników ryzyka, za to częściej występują te nietradycyjne, jak choroby zapalne, obciążenia rodzinne czy zaburzenia psychiczne. Leczenie tych chorych okazuje się mniej zgodne z zaleceniami – rzadziej otrzymują statyny, ACE-I, β-blokery czy leki przeciwpłytkowe – dlatego poprawa rokowania zaczyna się od poprawy terapii, w tym intensyfikacji statyn i zwiększenia stosowania pełnego GDMT. Kluczową rolę w ocenie ryzyka odgrywają trzy markery: LDL-C, hsCRP i LP(a), z których każdy niezależnie przewiduje ryzyko zawału, choć aktualne skale ryzyka uwzględniają jedynie LDL-C, dlatego konieczne jest ich uzupełnienie o hsCRP>3 i LP(a)>30. Wreszcie, coraz większego znaczenia nabiera koncepcja zapalna zawału serca, obejmująca zarówno intensywną kontrolę stanu zapalnego – od leczenia infekcji i dbałości o styl życia, po potencjalne terapie przeciwzapalne w rodzaju kolchicyny czy IL-1β-inhibitorów – jak i pełną modyfikację skal ryzyka, bo pacjent SMuRFs-less, pozbawiony tradycyjnych czynników, ma w pierwszym roku prawie dwukrotnie wyższe ryzyko zgonu niż ten klasyczny, palący tytoń czy z hiperlipidemią. Szczegółowy TRANSKRYPT do odcinka.Podcast jest przeznaczony wyłącznie dla osób z profesjonalnym wykształceniem medycznym.

#11 2025: Uordnede proteiner bryder med den traditionelle forestilling om, at proteiner kun fungerer, når de har en fast form. Professor Birthe B. Kragelund undersøger, hvordan disse fleksible proteiner alligevel kan indgå i centrale processer i celler, og hvorfor ændringer i dem kan føre til sygdom. Sammen med sin forskningsgruppe bruger hun avanceret NMR-spektroskopi til at kortlægge, hvordan proteiner, der konstant skifter form, binder til andre molekyler og påvirker cellernes funktion. Med støtte fra Carlsbergfondet undersøger hun desuden, om netop denne fleksibilitet kan have spillet en rolle i livets tidligste udvikling. Før livet opstod, fandtes aminosyrer i to spejlvendte varianter, men undervejs blev kun den ene selekteret i udviklingen af alle levende organismer. Forskningsprojektet søger at forstå, hvorfor dette skifte skete. Vært er Nynne Bjerre Christensen

This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor field your most urgent metabolic health questions—exploring care advocacy, novel drug use, lab results, and how to filter fact from fiction in the TikTok age. Dr. Cooper offers clinical clarity, real-world perspective, and actionable hope—with an emphasis on what truly matters for your long-term health and energy.Hear from listeners experiencing real breakthroughs (and challenges) with GLP-1s, get tips for navigating confusing cholesterol results, and learn why self-advocacy and good science matter more than credentials or hype. This is not a quick-fix episode; it's real metabolic medicine, mythbusting, and grounded encouragement for your health journey.Key Questions AnsweredWhat labs and scores best assess your true metabolic risk—and how do you make sense of fasting glucose, glucose-insulin ratio (GIR), and FIB-4?How can you find a medical provider who'll actually give you the time and attention metabolic care requires?Why do GLP-1s benefit more than weight loss alone? Listeners report help with sleep apnea, inflammation, and food noise—what does the science say?How should you reintroduce carbs after restriction, and what's the safest way to monitor (beyond A1C)?What's up with rising cholesterol on Zepbound, and when do you worry?Does serotonin syndrome relate to GLP-1s? (Short answer: No—Dr. Cooper explains why.)What are the dangers of “GLP-1 microdosing” as pushed by social media, and what happens when influencers overstep good science?Key TakeawaysCare that cares: The best doctor isn't always the most credentialed—find someone, MD, NP, or PA, who takes your questions seriously and goes deeper than the surface. Labs that matter: Fasting glucose, insulin, GIR, HbA1c, plus advanced lipid testing (CardioIQ, NMR) are critical for uncovering hidden risk—not just chasing numbers. GLP-1s act broadly: Listeners see gains in sleep, inflammation, and appetite regulation. These benefits are real, not just anecdotal, and Dr. Cooper shares the clinical rationale. Smart fueling, even on GLP-1s: If you lack hunger cues, “mechanical eating” prevents under-fueling and cellular stress—especially important for maintaining muscle and metabolism. Rethinking “microdosing”: TikTok trends are not medical advice—microdosing with black-market GLP-1s is unproven, poorly regulated, and potentially unsafe. Rely on trusted, legal medication sources only. Dr. Cooper's Actionable TipsRequest a full panel for metabolic health: ask your provider about fasting insulin, GIR, HbA1c, lipids, and FIB-4—even if you haven't been flagged as “at risk”. For those on GLP-1s: Don't skip meals; create a schedule with protein and fiber to avoid muscle loss and ensure micronutrient intake. Experiencing cholesterol shifts on medication? Ask for a breakdown (HDL, LDL, particle size) and consider advanced panels (CardioIQ, NMR) to better understand your risk. If reintroducing carbs after restriction, pair them with protein or fat and test glucose/insulin at intervals post-meal to personalize your plan. Avoid unregulated “microdosing” and buy only from reputable, FDA-approved outlets—protect your long-term health over quick fixes. Notable Quote“The most important thing is somebody who cares, not necessarily their degrees.”— Dr. Emily CooperLinks & ResourcesPodcast Home: Fat Science Podcast WebsiteSubmit a Show Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.comDr. Emily Cooper on LinkedInMark Wright on LinkedInAndrea Taylor on InstagramAdvanced cholesterol testing: CardioIQ at Quest, NMR at LabCorpFat Science is your source for breaking diet myths and advancing the science of true metabolic health. No diets, no agendas—just science that makes you feel better. The show is informational only and does not constitute medical advice. 

In this episode, Benjamin Levy, MD, FASCO, and Alex Spira, MD, PhD, FASCO, discuss the latest developments in targeting TROP2 and TIGIT for the treatment of lung cancer, including:TROP2-targeting ADCs: datopotamab deruxtecan, sacituzumab govitecan, sacituzumab tirumotecan TROP2 ADCS for patients with EGFR-mutated NSCLCTIGIT-targeting agents: domvanalimab, rilvegostomigPresenters:Benjamin Levy, MD, FASCOAssociate ProfessorJohns Hopkins School of MedicineClinical DirectorJohns Hopkins Kimmel Cancer Center, National Capitol Region (NCR)Washington, DCAlex Spira, MD, PhD, FASCODirector Clinical ResearchVirginia Cancer SpecialistsCEO NEXT Oncology VirginiaFairfax, VirginiaContent based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.Link to full program:https://bit.ly/4qZLR6B Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Join Dr. Kay and renowned female longevity expert Kayla Barnes for a comprehensive discussion on optimal health, moving far beyond "normal" lab ranges to an optimal state. Kayla breaks down essential longevity strategies, from tailoring sleep and exercise protocols to the female cycle and structuring supplements into three categories (baseline, protocol-based, and longevity molecules), to pursuing advanced testing like NMR panels. The episode explores cutting-edge therapies like Hyperbaric Oxygen (HBOT) for enhanced healing and blood flow, and Therapeutic Plasma Exchange (TPE) for reducing the total toxic burden. Finally, Dr. Kay and Kayla align on an approach to aesthetic longevity that advocates for a moderated use of pure core neurotoxins like Xeomin in combination with powerful collagen biostimulation and DNA-repairing molecules, such as polynucleotides, for true inside-out rejuvenation.

Die Themen in den Wissensnachrichten: +++ Gekringelter Sehnerv beim Chamäleon +++ umweltfreundlichere Klimakonferenz +++ "Band der Löcher" in Peru +++**********Weiterführende Quellen zu dieser Folge:A new twist in the evolution of chameleons uncovers an extremely specialized optic nerve morphology, Scientific Reports, 10.11.2025Quantifying the carbon footprint of conference travel: the case of NMR meetings, Magnetic Ressonance, 10.11.2025Indigenous accounting and exchange at Monte Sierpe (‘Band of Holes') in the Pisco Valley, Peru; Antiquity, 10.11.2025LAMP: laser-assisted melt printing for direct silica glass 3D printing with in situ nanoparticle synthesis, Materials & Design, Dezember-Ausgabe 2025Multilingualism protects against accelerated aging in cross-sectional and longitudinal analyses of 27 European countries, Nature Aging, 10.11.2025**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Join us for a conversation with Yining Ji Chen, recipient of the 2025 ACS Rising Star Award, on how mechanistic insight powers innovation in pharmaceutical process research. We dive into her career journey and standout projects—from Pd-catalyzed C–N coupling for HCV therapy to dynamic phosphorylation in nucleotide synthesis—plus her creation of LED‑NMR for real-time photochemical reaction monitoring. Hear how deep mechanistic understanding drives robustness and safety, why she moved to the Data‑Rich Measurements group, and which emerging analytical technologies excite her most. A celebration of scientific rigor shaping efficient, reliable pharma processes!Read some of the papers we discussed today:A multifunctional catalyst that stereoselectively assembles prodrugs - ScienceA rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions - Chem SciLED-Illuminated NMR Spectroscopy: A Practical Tool forMechanistic Studies of Photochemical Reactions - ChemPhotoChemFrom at-line to online NMR: coupling probe-based autosampler with benchtop NMR - Reaction Chemistry and EngineeringFollow the Pharm to Table podcast on X - ⁠⁠⁠⁠@PharmtoTablePod⁠⁠⁠⁠Visit our website at ⁠⁠⁠⁠⁠⁠⁠⁠https://podcasters.spotify.com/pod/show/pharm-to-table⁠⁠⁠⁠

Join Dr. Kay and renowned female longevity expert Kayla Barnes for a comprehensive discussion on optimal health, moving far beyond "normal" lab ranges to an optimal state. Kayla breaks down essential longevity strategies, from tailoring sleep and exercise protocols to the female cycle and structuring supplements into three categories (baseline, protocol-based, and longevity molecules), to pursuing advanced testing like NMR panels and Homa IR to decode health data. The episode explores cutting-edge therapies like Hyperbaric Oxygen (HBOT) for enhanced healing and blood flow, and Therapeutic Plasma Exchange (TPE) for reducing the total toxic burden. Finally, Dr. Kay and Kayla align on an approach to aesthetic longevity that advocates for a moderated use of pure core neurotoxins like Xeomin in combination with powerful collagen biostimulation and DNA-repairing molecules, such as polynucleotides, for true inside-out rejuvenation.

The podcast explores the importance of verifying the source and authenticity of nutritional products, particularly omega-3 fish oils. The host speaks with Svien, the co-founder and CEO of ORIVO, a Norwegian company that uses advanced NMR (nuclear magnetic resonance) technology to verify the species and origin of fish oils. The episode underscores the value of rigorous verification to protect consumers, maintain trust, and ensure the highest quality nutrition. Enjoy!ontargetliving.com

Peter Maurer, Assistant Professor of Molecular Engineering at the University of Chicago Pritzker School of Molecular Engineering, speaks with Pitt's HexAI podcast host, JordanGass-Pooré, about the future impact of quantum sensing on biomedical research and diagnostics.Peter's research lab leverages the extreme environmental sensitivity of quantum systems to develop powerful sensors suitable for cutting-edge biological research that are optically addressable and can operate under ambient conditions. He outlines both near-term and future applications of powerful quantum sensors in pathology and laboratory medicine. He provides a key example of how these sensors could enable a new type of nanoscale NMR spectroscopy, capable of measuring magnetic fields from biomolecules to non-invasively probe their chemical information and signaling pathways. In the near future, he points to diagnostic tools, currently being developed by companies, that use the unique optical signatures of quantum sensors for highly sensitive, background-free protein detection in small volumes. For the long term, he envisions the technology as a "field opener" for studying protein aggregation in neurodegenerative diseases like Alzheimer's and Parkinson's.Peter outlines how AI can be applied to analyze complex data from sensors that respond to multiple environmental factors and highlights the challenge of bringing together experts from quantum technology, biophysics, and medicine who can "talk each other's language.” He also touches on how the use of synthetic data in quantum sensing is a "completely under-appreciated" area with the potential to analyze complex environmental properties that would otherwise be missed by looking at single types of measurements. To advance the field from academic proofs-of-concept to clinical tools, he stresses the need for collaboration with academic and industry partners who can help engineer robust, "turnkey" systems that can be widely tested and used.The University of Pittsburgh Health and Explainable AI podcast is a collaborative initiative between the Health and Explainable AI (HexAI) Research Laboratory in the Department of Health Information Management at the School of Health and Rehabilitation Sciences, and the Computational Pathology and AI Center of Excellence (CPACE), at the University of Pittsburgh School of Medicine.Hosted by Jordan Gass-Pooré, a health and science reporter, this podcast series explores the transformative integration of responsible and explainable artificial intelligence into health informatics, clinical decision-making, and computational medicine. From reshaping diagnostic accuracy to enhancing patient care pathways, we'll highlight how AI is creating new bridges between researchers, clinicians, and healthcare innovators. Led by Ahmad P. Tafti, Hooman Rashidi and Liron Pantanowitz, the HexAI podcast is committed to democratizing knowledge around ethical, explainable, and clinically relevant AI. Through insightful conversations with domain experts, AI practitioners and students will spotlight the latest breakthroughs, discuss real-world applications, and unpack the challenges and opportunities that lie ahead in responsible AI in healthcare. So whether you're a student, practitioner, researcher, or policymaker, this is your gateway to the future of AI-powered healthcare

I sann sommaravsnittsanda drar vi ut på uppsnacket så långt det går och pratar lego-kopior och patent, men sen kommer vi igång och pratar om de senaste av Moderaternas säkerhetsskandaler, med en aktivt barn-nazist i Johan Forssells närhet. Martin har också läst en rapport om USAs båtbyggande. För kontakt och uppdateringar med Eld och rörelse […]

När tidskriften Expo börjar kartlägga ett chattforum inom extremhögern upptäcker de att en av de mer aktiva har en nära koppling till en av landets ministrar. De digitala spåren leder rakt in i den våldsamma rörelsen Aktivklubb Sverige. Lyssna på alla avsnitt i Sveriges Radio Play. Expos avslöjande den första juli slår ner som en bomb; en nära anhörig till en svensk minister har deltagit aktivt och rekryterat andra in i den våldsbejakande extremhögern.”Det handlar om en säkerhetsfråga, ett missförhållande i den svenska statsledningen som vi har avslöjat”, säger Erik Glaad på Expo. Men om det utgjort ett säkerhetshot vill ingen ansvarig svara på.När granskningen tar sin början är det för att följa den rasideologiska föreningen Det Fria Sverige som försöker få igång sin ungdomsverksamhet. Men liksom Nordiska Motståndsrörelsen, NMR, så har Det Fria Sverige svårt att konkurrera med den mer våldsamma och nu starkast växande rörelsen inom extremhögern - Aktivklubb Sverige - som även den nära anhörige blir en del av. Där lockas unga män av häftiga propagandaklipp som läggs ut i sociala medier.”Man ser maskerade män i rånarluvor som tränar kampsport. Det är dramatisk musik, snabba klipp, rök, eld. Det är imponerande så klart”, säger Christoffer Röstlund Jonsson på Dagens ETC som granskat Aktivklubb Sverige.P3 Krim har sökt den berörda ministern som ej återkommit. Statsminister Ulf Kristersson och SÄPO har avböjt att medverka.Programledare: Petra Berggren och Pernilla WadebäckReporter: David OhlssonProducent: Pernilla WadebäckLjudtekniker: Fredrik NilssonKontakt: p3krim@sverigesradio.seTipstelefon: 0734-61 29 15 (samma på Signal)

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Audio FileGround Truths can also be found on Apple Podcasts, Spotify and YouTube.The UK is the world leader in human genomics, and laid the foundation for advancing medicine with the UK Biobank, Genomes England and now Our Future Health (w/ 5 million participants). Sir John Bell is a major force in driving and advising these and many other initiatives. After 22 years as the Regius Professor of Medicine at the University of Oxford he left in 2024 to be President of the Ellison Institute of Technology. Professor Bell has been duly recognized in the UK: knighted in 2015 and appointed Companion of Honor in 2023. In our conversation, you will get a sense for how EIT will be transformational for using A.I. and life science for promoting human health.Transcript with audio links Eric Topol (00:06):Hello, this is Eric Topol from Ground Truths. And I'm really delighted to welcome today, Sir John Bell who had an extraordinary career as a geneticist, immunologist, we'll talk about several initiatives he's been involved with during his long tenure at University of Oxford, recently became head of the Ellison Institute of Technology (EIT) in the UK. So welcome, John.Sir John Bell (00:30):Thanks, Eric. Thanks very much for having me.Eric Topol (00:34):Well, I think it's just extraordinary the contributions that you have made and continue to make to advance medicine, and I thought what we could do is get into that. I mean, what's interesting, you have had some notable migrations over your career, I think starting in Canada, at Stanford, then over as Rhodes Scholar in Oxford. And then you of course had a couple of decades in a very prestigious position, which as I understand was started in 1546 by King Henry VII, and served as the Regius Professor of Medicine at the University of Oxford. Do I have that right?Sir John Bell (01:11):It was actually Henry VIII, but you were close.Eric Topol (01:14):Henry VIII, that's great. Yeah. Okay, good. Well, that's a pretty notable professorship. And then of course in recent times you left to head up this pretty formidable new institute, which is something that's a big trend going on around the world, particularly in the US and we'll talk about. So maybe we can start with the new thing. Tell us more about the Ellison Institute of Technology (EIT), if you will.Sir John Bell (01:47):Yeah. So as you know, Larry Ellison has been one of the great tech entrepreneurs focused really on developing terrific databases over his career and through Oracle, which is the company that he founded. And Larry is really keen to try and give back something substantial to the world, which is based on science and technology. So he and I did quite a bit together over the Covid pandemic. He and I talked a lot about what we're doing and so on. He came to visit afterwards and he had, I think he decided that the right way to make his contributions would be to set up an institute that would be using the state-of-the-art science and technology with a lot of AI and machine learning, but also some of the other modern tools to address the major problems in healthcare, in food security, in green energy and climate change and in global governance.Sir John Bell (02:49):So anyway, he launched this about 18 months ago. He approached me to ask whether I would run it. He wanted to set it up outside Oxford, and he wanted to do something which is a bit different than others. And that is his view was that we needed to try and create solutions to these problems which are commercially viable and not all the solutions are going to be commercially viable, but where you can create those, you make them sustainable. So the idea is to make sure that we create solutions that people want to buy, and then if they buy them, you can create a sustainable solution to those issues. So we are actually a company, but we are addressing many of the same problems that the big foundations are addressing. And the big issues that you and I talk about in health, for example, are all on our list. So we're kind of optimistic as to where this will go and Larry's supporting the project and we're going to build out an institute here which will have about 5,000 people in it, and we'll be, I think a pretty exciting new addition to the science and technology ecosystem globally.Eric Topol (04:02):Well, I know the reverberations and the excitement is palpable and some of the colleagues I've spoken to, not just in England, but of course all over the world. So congratulations on that. It was a big move for you to leave the hardcore academics. And the other thing I wanted to ask you, John, is you had distinguished your career in immunology, in genetics, type 1 diabetes and other conditions, autoimmune conditions, and now you've really diversified, as you described with these different areas of emphasis at the new institute. Is that more fun to do it or do you have deputies that you can assign to things like climate change in other areas?Sir John Bell (04:50):Trust me, Eric, I'm not making any definitive decisions about areas I know nothing about, but part of this is about how do you set up leadership, run a team, get the right people in. And I have to say one of the really interesting things about the institute is we've been able to recruit some outstanding people across all those domains. And as you know, success is almost all dependent on people. So we're really pretty optimistic we're going to have a significant impact. And of course, we also want to take risks because not a lot of point in us doing stuff that everybody else is doing. So we're going to be doing some things that are pretty way out there and some of them will fail, so we are just going to get used to trying to make sure we get a few of them across the finish line. But the other thing is that, and you've experienced this too, you never get too old to learn. I mean, I'm sucking up stuff that I never thought I would ever learn about, which is fun actually, and really marvel.Eric Topol (05:55):It's fantastic. I mean, you've really broadened and it's great that you have the runway to get these people on board and I think you're having a big building that's under construction?Sir John Bell (06:07):Yeah, we've got the original building that Larry committed to is about 330,000 square feet of space. I mean, this is completely amazing, but we are of course to accommodate up to 5,000 people, we're going to need more than that. So we are looking at a much wider campus here that'll involve more than just that building. I think we'll end up with several million square feet of space by the time we're finished. So mean, it's a really big project, but we've already made progress in some domains to try and get projects and the beginnings of companies on the road to try and solve some of the big problems. So we're quite excited about it.Eric Topol (06:49):Now you, I assume it's pretty close to Oxford, and will you have some kind of inter interactions that are substantial?Sir John Bell (06:58):Yeah, so the university's been terrific about this actually, because of course most universities would say, well, why don't you do it inside the university and just give us the money and it'll all be fine. So of course Larry. Larry wasn't born yesterday, so I said, well, thank you very much, but I think we'll probably do this nearby. But the university also realized this is a really exciting opportunity for them and we've got a really good relationship with them. We've signed an agreement with them as to who will work where. We've agreed not to steal a lot of their staff. We're going to be bringing new people into the ecosystem. Some of the university people will spend some time with us and sometime in the university, so that will help. But we're also bringing quite a few new people into the setting. So the university has been really positive. And I think one of the things that's attractive to the university, and you'll be familiar with this problem in the UK, is that we're quite good. The discovery science here is pretty good.Sir John Bell (08:06):And we do startups now at scale. So Oxford does lots of little startup companies in the biotech space and all the rest of it, but we never scale any of these companies because there isn't the depth of capital for scaling capital to get these things scaled. And so, in a way what we're trying to do here at Ellison actually avoids that problem because Larry knows how to scale companies, and we've got the financial support now. If we have things that are really successful, we can build the full stack solution to some of these problems. So I think the university is really intrigued as to how we might do that. We're going to have to bring some people in that know how to do that and build billion dollar companies, but it's sufficiently attractive. We've already started to recruit some really outstanding people. So as a way to change the UK system broadly, it's actually quite a good disruptive influence on the way the thing works to try and fix some of the fundamental problems.Eric Topol (09:07):I love that model and the ability that you can go from small startups to really transformative companies have any impact. It fits in well with the overall objectives, I can see that. The thing that also is intriguing regarding this whole effort is that in parallel we've learned your influence. The UK is a genomics world leader without any question and no coincidence that that's been your area of emphasis in your career. So we've watched these three initiatives that I think you were involved in the UK Biobank, which has had more impact than any cohort ever assembled. Every day there's another paper using that data that's coming out. There's Genomes England, and then now Our Future Health, which a lot of people don't know about here, which is well into the 5 million people enrollment. Can you tell us about, this is now 15 years ago plus when these were started, and of course now with a new one that's the biggest ever. What was your thinking and involvement and how you built the UK to be a world leader in this space?Sir John Bell (10:26):So if you turn the clock back 20 years, or actually slightly more than 25 years ago, it was clear that genomics was going to have a play. And I think many of us believed that there was going to be a genetic element to most of the major common disease turn out to be true. But at the time, there were a few skeptics, but it seemed to us that there was going to be a genetic story that underpinned an awful lot of human disease and medicine. And we were fortunate because in Oxford as you know, one of my predecessors in the Regius job was Richard Doll, and he built up this fantastic epidemiology capability in Oxford around Richard Peto, Rory Collins, and those folks, and they really knew how to do large scale epidemiology. And one of the things that they'd observed, which is it turns out to be true with genetics as well, is a lot of the effects are relatively small, but they're still quite significant. So you do need large scale cohorts to understand what you're doing. And it was really Richard that pioneered the whole thinking behind that. So when we had another element in the formula, which was the ability to detect genetic variation and put that into the formula, it seemed to me that we could move into an era where you could set up, again, large cohorts, but build into the ability to have DNA, interrogate the DNA, and also ultimately interrogate things like proteomics and metabolomics, which were just in their infancy at that stage.Sir John Bell (12:04):Very early on I got together because I was at that stage at the Nuffield Chair of Medicine, and I got together, Rory and Richard and a couple of others, and we talked a little bit about what it would look like, and we agreed that a half a million people late to middle age, 45 and above would probably over time when you did the power calculations, give you a pretty good insight in most of the major diseases. And then it was really a question of collecting them and storing the samples. So in order to get it funded at the time I was on the council of the MRC and George Radda, who you may remember, was quite a distinguished NMR physiologist here. He was the chief executive of the MRC. So I approached him and I said, look, George, this would be a great thing for us to do in the UK because we have all the clinical records of these people going back for a decade, and will continue to do that.Sir John Bell (13:01):Of course, we immediately sent it out to a peer review committee in the MRC who completely trashed the idea and said, you got to be joking. So I thought, okay, that's how that lasted. And I did say to George, I said, that must mean this is a really good idea because if it had gone straight through peer review, you would've known you were toast. So anyway, I think we had one more swing at peer review and decided in the end that wasn't going to work. In the end, George to his credit, took it to MRC council and we pitched it and everybody thought, what a great idea, let's just get on and do it. And then the Wellcome came in. Mark Walport was at the Wellcome at the time, great guy, and did a really good job at bringing the Wellcome on board.Sir John Bell (13:45):And people forget the quantum of money we had to do this at the time was about 60 million pounds. I mean, it wasn't astonishly small. And then of course we had a couple of wise people who came in to give us advice, and the first thing they said, well, if you ever thought you were really going to be able to do genetics on 500,000 people, forget it. That'll never work. So I thought, okay, I'll just mark that one out. And then they said, and by the way, you shouldn't assume you can get any data from the health service because you'll never be able to collect clinical data on any of these people. So I said, yeah, yeah, okay, I get it. Just give us the money and let us get on. So anyway, it's quite an interesting story. It does show how conservative the community actually is for new ideas.Sir John Bell (14:39):Then I chaired the first science committee, and we decided about a year into it that we really needed the chief executive. So we got Rory Collins to lead it and done it. I sat on the board then for the next 10 years, but well look, it was a great success. And as you say, it is kind of the paradigm for now, large genetic epidemiology cohorts. So then, as you know, I advise government for many years, and David Cameron had just been elected as Prime Minister. This was in about 2010. And at the time I'd been tracking because we had quite a strong genomics program in the Wellcome Trust center, which I'd set up in the university, and we were really interested in the genetics of common disease. It became clear that the price of sequencing and Illumina was now the clear leader in the sequencing space.Sir John Bell (15:39):But it was also clear that Illumina was making significant advances in the price of sequencing because as you remember, the days when it cost $5,000 to do a genome. Anyway, it became clear that they actually had technology that gets you down to a much more sensible price, something like $500 a genome. So I approached David and I said, we are now pretty sure that for many of the rare diseases that you see in clinical practice, there is a genetic answer that can be detected if you sequenced a whole genome. So why don't we set something up in the NHS to provide what was essentially the beginnings of a clinical service to help the parents of kids with various disabilities work out what's going on, what's wrong with their children. And David had had a child with Ohtahara syndrome, which as you know is again, and so David was very, he said, oh God, I'll tell you the story about how awful it was for me and for my wife Samantha.Sir John Bell (16:41):And nobody could tell us anything about what was going on, and we weren't looking for a cure, but it would've really helped if somebody said, we know what it is, we know what the cause is, we'll chip away and maybe there will be something we can do, but at least you know the answer. So anyway, he gave us very strong support and said to the NHS, can you please get on and do it? Again massive resistance, Eric as you can imagine, all the clinical geneticists said, oh my God, what are they doing? It's complete disaster, dah, dah, dah. So anyway, we put on our tin hats and went out and got the thing going. And again, they did a really good job. They got to, their idea was to get a hundred thousand genomes done in a reasonable timeframe. I think five years we set ourselves and the technology advance, people often underestimate the parallel development of technology, which is always going on. And so, that really enabled us to get that done, and it still continues. They're doing a big neonatal program at the moment, which is really exciting. And then I was asked by Theresa May to build a life science strategy because the UK, we do this stuff not as big and broad as America, but for a small country we do life sciences pretty well.Eric Topol (18:02):That's an understatement, by the way. A big understatement.Sir John Bell (18:04):Anyway, so I wrote the strategies in 2017 for Theresa about what we would do as a nation to support life sciences. And it was interesting because I brought a group of pharma companies together to say, look, this is for you guys, so tell us what you want done. We had a series of meetings and what became clear is that they were really interested in where healthcare was going to end up in the next 20 years. And they said, you guys should try and get ahead of that wave. And so, we agreed that one of the domains that really hadn't been explored properly, it was the whole concept of prevention.Sir John Bell (18:45):Early diagnosis and prevention, which they were smart enough to realize that the kind of current paradigm of treating everybody in the last six months of life, you can make money doing that, there's no doubt, but it doesn't really fix the problem. And so, they said, look, we would love it if you created a cohort from the age of 18 that was big enough that we could actually track the trajectories of people with these diseases, identify them at a presymptomatic stage, intervene with preventative therapies, diagnose diseases earlier, and see if we could fundamentally change the whole approach to public health. So we anyway, went back and did the numbers because of course at much wider age group, a lot of people don't get at all sick, but we thought if we collected 5 million people, we would probably have enough. That's 10% of the UK adult population.Sir John Bell (19:37):So anyway, amazingly the government said, off you go. We then had Covid, which as you know, kept you and I busy for a few years before we could get back to it. But then we got at it, and we hired a great guy who had done a bit of this in the UAE, and he came across and we set up a population health recruitment structure, which was community-based. And we rapidly started to recruit people. So we've now got 2.9 million people registered, 2.3 million people consented, and we've got blood in the bank and all the necessary data including questionnaire data for 1.5 million people growing up. So we will get to 5 million and it's amazing.Eric Topol (20:29):It is. It really is, and I'm just blown away by the progress you've made. And what was interesting too, besides you all weren't complacent about, oh, we got this UK Biobank and you just kept forging ahead. And by the way, I really share this importance of finally what has been a fantasy of primary prevention, which never really achieved. It's always, oh, after a heart attack. But that's what I wrote about in the Super Agers book, and I'll get you a copy.Sir John Bell (21:02):No, I know you're a passionate believer in this and we need to do a lot of things. So we need to work out what's the trial protocol for primary prevention. We need to get the regulators on board. We've got to get them to understand that we need diagnostics that define risk, not disease, because that's going to be a key bit of what we're going to try and do. And we need to understand that for a lot of these diseases, you have to intervene quite early to flatten that morbidity curve.Eric Topol (21:32):Yeah, absolutely. What we've learned, for example, from the UK Biobank is not just, of course the genomics that you touched on, but the proteomics, the organ clocks and all these other layers of data. So that gets me to my next topic, which I know you're all over it, which is AI.Eric Topol (21:51):So when I did the NHS review back in 2018, 2019, the group of people which were amazing that I had to work with no doubt why the UK punches well beyond its weight. I had about 50 people, and they just said, you know what? Yeah, we are the world leaders in genomics. We want to be the world leader in AI. Now these days you only hear about US and China, which is ridiculous. And you have perhaps one of the, I would say most formidable groups there with Demis and Google DeepMind, it's just extraordinary. So all the things that the main foci of the Ellison Institute intersect with AI.Sir John Bell (22:36):They do. And we, we've got two underpinning platforms, well actually three underpinning platforms that go across all those domains. Larry was really keen that we became a real leader in AI. So he's funded that with a massive compute capacity. And remember, most universities these days have a hard time competing on compute because it's expensive.Eric Topol (22:57):Oh yeah.Sir John Bell (22:58):So that is a real advantage to us. He's also funded a great team. We've recruited some people from Demis's shop who are obviously outstanding, but also others from around Europe. So we really, we've recruited now about 15 really outstanding machine learning and AI people. And of course, we're now thinking about the other asset that the UK has got, and particularly in the healthcare space is data. So we do have some really unique data sets because those are the three bits of this that you need if you're going to make this work. So we're pretty excited about that as an underpinning bit of the whole Ellison Institute strategy is to fundamentally underpin it with very strong AI. Then the second platform is generative biology or synthetic biology, because this is a field which is sort of, I hesitate to say limped along, but it's lacked a real focus.Sir John Bell (23:59):But we've been able to recruit Jason Chin from the LMB in Cambridge, and he is one of the real dramatic innovators in that space. And we see there's a real opportunity now to synthesize large bits of DNA, introduce them into cells, microbes, use it for a whole variety of different purposes, try and transform plants at a level that people haven't done before. So with AI and synthetic biology, we think we can feed all the main domains above us, and that's another exciting concept to what we're trying to do. But your report on AI was a bit of a turning point for the UK because you did point out to us that we did have a massive opportunity if we got our skates, and we do have talent, but you can't just do it with talent these days, you need compute, and you need data. So we're trying to assemble those things. So we think we'll be a big addition to that globally, hopefully.Eric Topol (25:00):Yeah. Well that's another reason why I am so excited to talk to you and know more about this Ellison Institute just because it's unique. I mean, there are other institutes as like Chan Zuckerberg, the Arc Institute. This is kind of a worldwide trend that we're seeing where great philanthropy investments are being seen outside of government, but none have the computing resources that are being made available nor the ability to recruit the AI scientists that'll help drive this forward. Now, the last topic I want to get into with you today is one that is where you're really grounded in, and that's the immune response.Eric Topol (25:43):So it's pretty darn clear now that, well, in medicine we have nothing. We have the white cell neutrophil to lymphocyte ratio, what a joke. And then on the other hand, we can do T and B cell sequencing repertoires, and we can do all this stuff, autoantibody screens, and the list goes on and on. How are we ever going to make a big dent in health where we know the immune system is such a vital part of this without the ability to check one's immune status at any point in time in a comprehensive way? What are your thoughts about that?Sir John Bell (26:21):Yeah, so you seem to be reading my mind there. We need to recruit you over here because I mean, this is exactly, this is one of our big projects that we've got that we're leaning into, and that is that, and we all experienced in Covid the ins and outs of vaccines, what works, what doesn't work. But what very clear is that we don't really know anything about vaccines. We basically, you put something together and you hope the trial works, you've got no intermediate steps. So we're building a really substantial immunophenotyping capability that will start to interrogate the different arms of the immune response at a molecular level so that we can use a combination of human challenge models. So we've got a big human challenge model facility here, use human challenge models with pathogens and with associated vaccines to try and interrogate which bits of the immune response are responsible for protection or therapy of particular immunologically mediated diseases or infectious diseases.Sir John Bell (27:30):And a crucial bit to that. And one of the reasons people have tried this before, but first of all, the depth at which you can interrogate the immune system has changed a lot recently, you can get a lot more data. But secondly, this is again, where the AI becomes important because it isn't going to be a simple, oh, it's the T-cell, it's going to be, well, it's a bit of the T cells, but it's also a bit of the innate immune response and don't forget mate cells and don't forget a bit of this and that. So we think that if we can assemble the right data set from these structured environments, we can start to predict and anticipate which type of immune response you need to stimulate both for therapy and for protection against disease. And hopefully that will actually create a whole scientific foundation for vaccine development, but also other kinds of immune therapy and things like cancer and potentially autoimmune disease as well. So that's a big push for us. We're just busy. The lab isn't set up. We've got somebody to run the lab now. We've got the human challenge model set up with Andy Pollard and colleagues. So we're building that out. And within six months, I think we'll be starting to collect data. So I'm just kind of hoping we can get the immune system in a bit more structured, because you're absolutely right. It's a bit pin the tail on the donkey at the moment. You have no idea what's actually causing what.Eric Topol (29:02):Yeah. Well, I didn't know about your efforts there, and I applaud that because it seems to me the big miss, the hole and the whole story about how we're going to advanced human health and with the recent breakthroughs in lupus and these various autoimmune diseases by just targeting CD19 B cells and resetting like a Ctrl-Alt-Delete of their immune system.Sir John Bell (29:27):No, it's amazing. And you wouldn't have predicted a lot of this stuff. I think that means that we haven't really got under the skin of the mechanistic events here, and we need to do more to try and get there, but there's steady advance in this field. So I'm pretty optimistic we'll make some headway in this space over the course of the next few years. So we're really excited about that. It's an important piece of the puzzle.Eric Topol (29:53):Yeah. Well, I am really impressed that you got all the bases covered here, and what a really exhilarating chance to kind of peek at what you're doing there. And we're going to be following it. I know I'm going to be following it very closely because I know all the other things that you've been involved with in your colleagues, big impact stuff. You don't take the little swings here. The last thing, maybe to get your comment, we're in a state of profound disruption here where science is getting gutted by a madman and his henchmen, whatever you want to call it, which is really obviously a very serious state. I'm hoping this is a short term hit, but worried that this will have a long, perhaps profound. Any words of encouragement that we're going to get through this from the other side of the pond?Sir John Bell (30:52):Well, I think regardless of the tariffs, the scientific community are a global community. And I think we need to remember that because our mission is a global mission, and we need to lean into that together. First of all, America is such a powerhouse of everything that's been done scientifically in the human health domain. But not only that, but across all the other domains that we work in, we can't really make the kind of progress that we need to without America being part of the agenda. So first of all, a lot of sympathy for you and your colleagues. I know it must be massively destabilizing for you, not be confident that the things that work are there to help you. But I'm pretty confident that this will settle down. Most of the science is for, well, all the science is really for public good, and I think the public recognizes it and they'll notice if it's not being prosecuted in the way that it has to be. And the global science community cannot survive without you. So we're all leaning in behind you, and I hope it will settle. One of my worries is that these things take years to set up and literally hours or minutes to destroy. So we can't afford to take years to set them back up again. So we do need to be a bit careful about that, but I still have huge confidence in what you guys can achieve and we're all behind you.Eric Topol (32:37):Well, that's really helpful getting some words of wisdom from you there, John. So this has been terrific. Thanks so much for joining, getting your perspective on what you're doing, what's important is so essential. And we'll stay tuned for sure.Sir John Bell (32:59):And come and visit us at the EIT, Eric. We'd be glad to see you.*******************************Some of the topics that John and I discussed—immunology, A.I., genomics, and prevention—are emphasized in my new book SUPER AGERS. A quick update: It will have a new cover after making the New York Times Bestseller list and is currently ranked #25 for all books on Amazon. Thanks to so many of you for supporting the book!Here are a few recent podcasts:Dax Shepard: Dr. Mike Sanjay Gupta ***********************Thanks for reading and subscribing to Ground Truths.If you found this interesting please share it!That makes the work involved in putting these together especially worthwhile.All content on Ground Truths— newsletters, analyses, and podcasts—is free, open-access.Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. Get full access to Ground Truths at erictopol.substack.com/subscribe

Dr. Martin answers questions sent in by our listeners. Some of today's topics include: Over-the-counter pain meds Edema & swollen ankles Low doses of statin drugs NAD supplements Floaters in eyes Preparing for pulmonary test Zinc & Alzheimer's NMR lipoprofile tests  

Daryn gives her review of both Cowboy Carter and Cotton Candy KitKats. John wants Daryn to see the new Marvel movie (what else is new!). Starting this week we are releasing NMR and our weekly cases in alternate weeks! Sign up for Patreon to get early access to EVERYTHING so you will never be late to the party! Watch and listen to this and every other episode several days early on Patreon! Patreon members can join us during our live recordings, comment on the case, participate in polls and get shout outs! Join for as little as $5 a month right here! Want Shaken and Disturbed merch? T-shirts, pillows, hoodies, phone cases, stickers and more are now available here: Shaken and Disturbed MERCH STORE Follow John on Twitter @jthrasher, Instagram @jthrasher and TikTok @johnthrasher Follow Daryn on Twitter @CarpeDaryn and Instagram @CarpeDaryn Join the official Shake and Disturbed Fans Facebook Group here! SUBSCRIBE TO SHAKEN AND DISTURBED ON YOUTUBE!

In this episode, Seth Tandett brings back Dr. Jon Belkowitz to unpack a powerful but often misunderstood tool in the concrete world—petrography. From diagnosing floor failures to proactively optimizing mix designs, Dr. Jon explains how petrography gives contractors, suppliers, and engineers a microscopic advantage. Whether you're battling ASR or just curious about those weird white streaks on your concrete, this episode is for you.

NMRThe National Johne's Management Plan Please note: The information provided during this podcast has been prepared for general informational purposes only and does not constitute advice. The information must not be relied upon for any purpose and no representation or warranty is given as to its accuracy, completeness or otherwise. Any reference to other organisations, businesses or products during the podcast are not endorsements or recommendations of Dairy Consulting Ltd or its affiliated companies. The views of the presenter are personal and may not be the views of Dairy Consulting Ltd. The contents of this podcast are the copyright of Dairy Consulting Ltd.

Lab test for health enthusiasts The yearly lab testing ordered by most doctors may not provide the full picture of your state of health. Cholesterol testing through NMR, measuring apolipoprotein B, and testing urinary hormone metabolites and the microbiome provide a deep dive into your disease risk. On this episode of Live Foreverish, Drs. Mike and Crystal review these advanced tests and more! #LELearn

Minister for Further and Higher Education, Research, Innovation and Science, James Lawless TD, has today announced a €17.7 million investment in nine research infrastructure projects through Research Ireland's Research Infrastructure Programme. The awards will contribute to the advancement of high-quality and high-impact research activities across Ireland. Announcing the funding, Minister Lawless commented: "This targeted investment in research infrastructure will help to future-proof the conducting of high-quality research endeavours across our higher education institutions and in a wide range of disciplines. It is important for researchers to be equipped with the innovative tools and the conducive environments that can help deliver research excellence and impact." In welcoming the announcement, Celine Fitzgerald, Interim Chief Executive of Research Ireland, said: "The Research Infrastructure Programme supports the research community in building and sustaining cutting-edge infrastructure to accomplish high-quality, impactful, and innovative research. The programme encourages partnerships and collaboration between different cohorts of researchers in Ireland, across academia and enterprise." Nine Irish research infrastructure projects The nine funded projects are: Coastal & Offshore ASV (Autonomous Surface Vehicle), University of Limerick, led by Prof. Gerard Dooly, aims to acquire a coastal and offshore autonomous surface vehicle (ASV) with a length of 9 meters and a range of 2500 nautical miles. This will enhance Ireland's marine science capabilities, bridge data gaps, and improve our understanding of ocean habitats. (€1,851,784) Cryo Electron Microscopy Unit National Platform, University College Dublin, led by Prof. Oliver Blacque, will establish a cryo-EM unit for high-resolution 3D visualisation of biological structures, aiding various biomedical research applications. (€3,749,322) NMR Centre of Expertise, Trinity College Dublin, led by Prof. Mathias Senge, will provide advanced NMR techniques for chemistry research, including a multi-channel 600MHz NMR and a 400MHz instrument for high-throughput analyses. (€2,649,497) Photon Counting CT for Cardiovascular and Oncology Research, Trinity College Dublin, led by Prof. James Meaney, will expand imaging capabilities with a Photon-counting CT scanner for advanced medical imaging in oncology and cardiovascular research. (€2,721,339) National Enteric Methane Mitigation Testbed, Teagasc, led by Dr Stephen Butler, will develop strategies to reduce methane emissions from ruminant animals, contributing to climate change mitigation. (€1,983,502) Characterising Earth Materials using Multi-Sensor Core Logger Analysis (Earth SCAn), University College Dublin, led by Prof. Peter Haughton, will advance the characterisation of Earth materials for interdisciplinary research into climate change, energy, and geohazards. (€600,113) Advanced Material Characterisation and Imaging Platform, Dublin City University, led by Dr Karsten Fleischer, will enhance material analysis capabilities with X-ray photoelectron spectroscopy (XPS) for various applications in ICT, energy, and medical devices. (€2,251,897) C-Trap: A Dynamic Single Molecule Platform for Chemical Biology and Biophysics, Dublin City University, led by Prof. Andrew Kellett, will enable single-molecule analysis for understanding molecular mechanisms of diseases, aiding biopharmaceutical and therapeutic research. (€948,901) Automated X-ray Photoelectron Spectroscopy (XPS), University College Dublin, led by Prof. Eoin Casey, will replace aging XPS equipment to enhance surface analysis capabilities for various research and industry applications. (€986,952) The awardees are from the following research bodies: University of Limerick (UL), University College Dublin (UCD), Trinity College Dublin (TCD), Teagasc, and Dublin City University (DCU). See more breaking stories here.

What if your body was sending warning signals years before disease struck—and you could actually see them? That's exactly what comprehensive blood testing offers, yet most people avoid or minimize the importance of regular lab work until symptoms appear. In this eye-opening conversation, fitness coach Derrick Wellock and his wife Cassie, a physician assistant who recently opened Vertical Primary Care within Double Edge Fitness, share their expertise on using blood work as your body's early warning system.Cassie explains how standard lab ranges reflect the average population rather than optimal health, and why "normal" results might still warrant attention, especially for those seeking longevity and peak performance. The couple dives deep into cholesterol testing, revealing why an advanced NMR panel that measures particle size offers far more valuable information than standard lipid profiles. Derrick transparently shares his personal journey with high cholesterol and how coconut oil—touted as healthy in fitness circles—sent his numbers "bonkers" virtually overnight.The discussion challenges common misconceptions about carbohydrates and insulin sensitivity, with both hosts explaining how strategically incorporating quality carbs actually improved Derrick's blood glucose levels. They also tackle hormone optimization for both men and women, providing a nuanced view of testosterone replacement therapy beyond the oversimplified approaches offered by many hormone clinics.Whether you're a fitness enthusiast who assumes external health equals internal health, someone avoiding medical care, or simply curious about preventative medicine, this episode offers practical guidance for using blood work as a powerful tool in your health journey. As Derrick aptly puts it: "Blood work is like your car's dashboard—it tells you when to act before the engine fails."Ready to take control of your health journey? Schedule those labs, establish your baseline, and discover what's really happening beneath the surface. The insights could add years of quality life to your future.Follow us on Instagram here! https://www.instagram.com/doubleedgefitness/

The Big One Hundred! With WYKD! Westway Yoga Kolectiv Dana also..... WICKED! WYKD BELIEVES IN A UNIFIED COMMUNITY AND THE HEALING BENEFITS OF YOGA FOR EVERYONE! I am so thrilled that my Nmr 100 is with these beautiful people behind WYKD a wonderful community yoga and mindfulness project from London! I have been honoured and blessed to have played a small part as a teacher within this project and now i am able to share the wonderful work of WYKD with the world! In this episode i speak with founders Lauren and Keri, two soul sisters i hold close to my heart! We discuss: What is WYKD and where did it all begin? The importance of the project and projects alike. How to make yoga and mindfulness accessible to everyone. Designing a schedule which is accessible to all ages, bodies and backgrounds of the community.The principles of DIVERSITY and INCLUSIVITY lie at the heart of this project, how to go about that. Music, a love for music and how music also CONNECTS different communities. Have a listen, share and SUPPORT them! https://www.wykd.uk/supportSHOWNOTES: https://www.wykd.uk/INSTAGRAM: wykd_ldn 

In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Molly Atkinson, Assistant Professor of Chemistry at the University of North Texas in Denton, TX, and her graduate student David Hamilton. Atkinson and Hamilton are experts in Chemistry Education Research (CER), and they recently published a paper discussing results of a survey of bachelors-level chemists working in industry that asked them “What does industry want new chemists to know?”. The paper, published earlier this year in the Journal of Chemical Education, generated quite a lot of buzz on analytical chemistry social media. In the conversation we talk about highlights from the article, and touch on potential future work that could fill in knowledge gaps identified by the first survey. The survey revealed some trends that will be familiar to readers of LCGC Magazine. For example, the surveyed chemists indicated that liquid and gas chromatography are two of the top five most important instrumental techniques that new chemists entering industry should know how to use. On the other hand, the survey also revealed some surprising results - for example, nuclear magnetic resonance (NMR) spectroscopy was not in the top-five instrumental techniques, despite that NMR occupies a prominent position in most undergraduate chemistry curricula in the United States. Finally, the guests and co-hosts discuss a bit about how Chemistry Education Research “works”, for listeners who are less familiar with this discipline than other more traditional research areas.

Gäster: Sebastian Järpehag, Christer Svensson, Jonathan Tengwall, Jonas Dillner För 90SEK/mån får du 5 avsnitt i veckan: 4 Vanliga AMK MORGON + AMK FREDAG med Isak Wahlberg www.patreon.com/amkmorgon STORY HOTEL AMK Morgons lyssnare har 30% rabatt på samtliga rumskategorier. Patreons har 40% rabatt på samtliga rumskategorier För att boka, gå in på hyatt.com och ange koden 165414 under "Corporate or Group Code" (viktigt att inte välja annan typ av rabattkod). UPPTÄCKA Köp ett fint mikroskop för barn! Upptäcka är en fin liten produkt som låter ditt barn från 5år och uppåt, upptäcka världen. Ett lättanvänt, portabelt mikroskop med 20 till 40 gångers förstoring och en 2 megapixel kamera som kan fånga både bilder och video på den lilla skärmen. En perfekt present till ditt barn nu inför sommarlovet. www.upptackatoys.com/amk eller discount koden “amk” i checkout (inte cart) så får du rabatt på ditt köp PRE-SAVEA AGNES NYA LÅT ”ELDEN” https://ninetone.link/elden Relevanta länkar: …Oasis https://www.aftonbladet.se/nojesbladet/a/xmJOrj/oasis-aterforenas-2025-hit-kommer-turnen https://www.expressen.se/noje/oasis-aterforenas/ https://en.wikipedia.org/wiki/Oasis_(band) https://www.youtube.com/watch?v=LvqfuvBPFTs …Jeff Goldblum om Oasis https://www.instagram.com/reel/C_LEfIIsmge/?igsh=OHh1cWl2ZTMxeDEz …Mofeta & Jerre https://sv.wikipedia.org/wiki/Mofeta_%26_Jerre …Sven Eriksson https://www.expressen.se/sport/fotboll/95-arige-pappan-om-sorgen-det-kommer-bli-tomt/ …Janne Anderssons Nigeriabrev https://www.dn.se/sport/janne-andersson-aktuell-for-nytt-jobb-under-tv-inspelning-pa-atlanten/ https://www.aftonbladet.se/sportbladet/fotboll/a/mPM57p/janne-andersson-blir-inte-ny-forbundskapten-for-landslaget-i-nigeria …Över Atlanten https://www.instagram.com/p/C--2VDZtlko/?hl=en&img_index=1 …astronauterna https://www.svt.se/nyheter/utrikes/astronauterna-fast-i-rymden-tvingas-lifta-med-spacex https://economictimes.indiatimes.com/magazines/panache/will-sunita-williams-soon-run-out-of-food-oxygen-at-space-station-nasa-clarifies/articleshow/112735023.cms?from=mdr …NMR-snubben https://www.aftonbladet.se/nyheter/a/vgkwBp/ki-forskare-fornekar-forintelsen-i-nmr-chatt …Talibanernas nya lagar https://www.dn.se/varlden/talibanerna-forbjuder-kvinnlig-sang-och-bilder-pa-levande-ting/ …Rymdstyrelsens logga https://www.rymdstyrelsen.se/contentassets/52b1d62defb04917a4de3859ed021113/rymdstyrelsen_ingang.jpg?width=454&rmode=crop&height=303&quality=80 Låtarna som spelades var: BAYRAKTAR is Life - Taras Borovko Hey Jude - The Beatles Werewolves of London - Warren Zevon Alla låtar finns i AMK Morgons spellista här: https://open.spotify.com/user/amk.morgon/playlist/6V9bgWnHJMh9c4iVHncF9j?si=so0WKn7sSpyufjg3olHYmg Stötta oss gärna på Swish, varje litet bidrag uppskattas enormt! 123 646 2006

In this episode of the Go Hard Chick podcast, Dr. William Davis, M.D., a cardiologist and New York Times bestselling author, shares his journey from conventional interventional cardiology to a more holistic approach to heart health.  Dr. Davis shared his personal journey, which was significantly influenced by the sudden cardiac death of his mother shortly after a successful coronary procedure. This event led him to explore and eventually advocate for preventive measures outside the conventional medical practices. Dr. Davis introduces us to the concept of the Milwaukee Heart Scan, a diagnostic tool that measures the amount of plaque in arteries and predicts potential heart attacks years before they might occur. He emphasizes the limitations of traditional treatments like statins and low-fat diets, which he argued do not effectively stop the progression of heart disease. Instead, Dr. Davis advocates for a more comprehensive approach that includes dietary changes, identifying and managing the real causes of heart disease through advanced testing like NMR lipoprotein testing, and addressing vitamin D deficiencies. A significant part of our discussion also revolved around the coronary calcium score, a test that Dr. Davis feels is underutilized in medical practice due to its low cost and lack of profitability for hospitals. He explained how this test could provide crucial early warnings for heart disease risk. Dr. Davis also touched on broader health issues, including the detrimental effects of modern wheat consumption, the importance of gut health, and the potential dangers of popular diabetes medications like Ozempic and Wegovy. He explained how these drugs could lead to muscle loss and subsequent weight gain post-treatment, worsening patients' overall health. This episode is packed with critical insights on preventive health care, the importance of dietary choices, and the need for a shift in how we manage and understand chronic diseases. Dr. Davis's expertise and innovative approaches to cardiology and overall health provided our listeners with valuable information to consider and potentially implement in their health routines. Learn More About Dr. Davis: ​Website:  https://drdavisinfinitehealth.com/ Latest Book: Super Gut Join the Go Hard Chick email list!:  https://mailchi.mp/e071daa1445b/g68zgxope4 Connect with me: Website: www.gohardchick.com Instagram: @gohardchick and @krisalisefit Facebook:  Kristal Holmes Music Credit Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/kidcut/jazz-and-hop License code: MBVBUMAM7ITD58CK Music from Uppbeat (free for Creators!): Whoosh - swift cut Jam FX Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Kristal Holmes disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician or therapist. --- Send in a voice message: https://podcasters.spotify.com/pod/show/gohardchick/message

The global health landscape faces unprecedented challenges, with diseases proliferating despite advances in medical knowledge and technology. Despite significant investment in research across multiple disciplines, including physics, chemistry, biology, and engineering, some diseases remain elusive to diagnosis and treatment. In contrast, pre-colonial India boasted a healthy populace with a robust understanding of health and effective indigenous medical systems like Ayurveda. However, the dominance of Western medicine during colonization marginalized these traditional practices. Now, there's a resurgence of interest worldwide, including in India, in alternative approaches like Ayurveda, signaling a shift away from solely chemical-based treatments. The systems approach of the Tridosha model of Ayurveda holds a lot of relevant and intriguing aspects that have been found to be effective in diagnosing and treating various physiological conditions. Having said that, in today's world, with the recent Patanjali lawsuit, it is important to delineate what is truly scientific within Ayurveda as well as protect this age-old tradition from those who want to destabilize it, due to ideological reasons. To discuss all this and more, we have with us one of Bharat's most illustrious practitioners and scholars of Ayurveda - Dr. Rama Jayasundar. Dr. Jayasundar heads the Department of NMR, AIIMS, New Delhi. She has had a rather fascinating trajectory, having received her doctorate in Physics from Cambridge University with training in Nuclear Magnetic Resonance. While pioneering biomedical NMR work in Bharat, she went for a medical degree in Ayurveda (BAMS – Bachelor of Ayurvedic Medicine and Surgery), and today is the only one at both the national and international levels to hold dual degrees in Physics and Ayurveda. Her current research interests harness the distinctive facets of her expertise (NMR, Physics, Ayurveda and Allopathy) to shed light on the scientific basis and working of Ayurveda. Snakes in the Ganga - http://www.snakesintheganga.com Varna Jati Caste - http://www.varnajaticaste.com The Battle For IIT's - http://www.battleforiits.com Power of future Machines - http://www.poweroffuturemachines.com 10 heads of Ravana - http://www.tenheadsofravana.com To support Infinity Foundation's projects including the continuation of such episodes and the research we do: इनफिनिटी फ़ौंडेशन की परियोजनाओं को अनुदान देने के लिए व इस प्रकार के एपिसोड और हमारे द्वारा किये जाने वाले शोध को जारी रखने के लिए: http://infinityfoundation.com/donate-2/ --- Support this podcast: https://podcasters.spotify.com/pod/show/rajivmalhotrapodcast/support

Whoa baby!  This was A LOT of fun.  Chris and Christian put together another spectacular production...the Ice Bath Challenge!  We are always talking about the benefits of a cold plunge so we decided it was time to share our experience with the NMR Board and a few other nutty members!  The gang does some warm up exercises, goes for a quick mile run, and then they prepare themselves for the chill!  We heard it all...laughing, crying, moaning, and screams of terror.  Join us for one of the most entertaining play by plays you'll ever hear.  We love you NMR!  Can't wait to do this again.  If you're interested in purchasing your own Nurecover Cold Plunge, feel free to use the code CHRISTIAN62079 for a discount.  We'll see you next time!  Until then, don't forget to get out there and...run as you are baby!

Chris and Christian meet up to give you a quick recap of the 2024 NYC Half Marathon!  It was an incredible day!  Beautiful weather and PRs for NMR!  Listen to us yammer on about how much fun we had and stick around to hear us go off the rails as usual!  We hope you enjoy the latest episode of Run As You Are...a conversation with people of all paces!

This lecture was given on October 11th, 2023, at Harvard University. For more information on upcoming events, visit us at thomisticinstitute.org/upcoming-events About the Speaker: Stephen Meredith is a professor at the University of Chicago's Departments of Pathology, Biochemistry and Molecular Biology, and Neurology. He is also an associate faculty member in the University of Chicago Divinity School. He has published more than 100 journal articles, focusing on the biophysics of protein structure. Much of his work has been the application of solution and solid-state NMR to the study of amyloid proteins associated with neurodegenerative diseases such as Alzheimer's Disease. He has also published articles on literature and philosophy in diverse aspects of medical humanities and bioethics. His teaching includes courses to graduate students in biochemistry and biophysics, medical students, and undergraduates and graduate students in the humanities, including courses on James Joyce's Ulysses, St. Thomas Aquinas, Augustine, Dostoevsky (focusing on Brothers Karamazov), Thomas Mann and David Foster Wallace. He is currently working on a book examining disease and the theological problem of evil. Other current writing projects include a study of James Joyce and the problem of evil.

Stephen Meredith is a professor at the University of Chicago's Departments of Pathology, Biochemistry and Molecular Biology, and Neurology. He is also an associate faculty member in the University of Chicago Divinity School. He has published more than 100 journal articles, focusing on the biophysics of protein structure. Much of his work has been the application of solution and solid-state NMR to the study of amyloid proteins associated with neurodegenerative diseases such as Alzheimer's Disease. He has also published articles on literature and philosophy in diverse aspects of medical humanities and bioethics. His teaching includes courses to graduate students in biochemistry and biophysics, medical students, and undergraduates and graduate students in the humanities, including courses on James Joyce's Ulysses, St. Thomas Aquinas, Augustine, Dostoevsky (focusing on Brothers Karamazov), Thomas Mann and David Foster Wallace. He is currently working on a book examining disease and the theological problem of evil. Other current writing projects include a study of James Joyce and the problem of evil.

Watch this NMR in video form on Patreon at any tier! John and Daryn get to the bottom of the age old question: is it correct to brush then floss or floss then brush!? It's John's first holidays with Magic. Sign up for Patreon here and watch the video version of this episode! And get bonus episodes of the show, exclusive blogs, videos, photos and direct access to John and Daryn! Starting at $5 a month, your contribution greatly supports our independent show! http://patreon.com/shakenanddisturbed Want Shaken and Disturbed merch? T-shirts, pillows, hoodies, phone cases, stickers and more are now available here: Shaken and Disturbed MERCH STORE Follow John on Twitter @jthrasher, Instagram @jthrasher and TikTok @johnthrasher Follow Daryn on Twitter @CarpeDaryn and Instagram @CarpeDaryn Join the official Shake and Disturbed Fans Facebook Group here! 

Surprise! John and Daryn met up in NYC to record this week's NMR (as well as Sunday's full episode)! They recap their love for each other, John's small Diet Cokes, and the US Open among other things! Our new Shaken and Disturbed Patreon perks and tiers are live NOW! Help support our show for as little as $5 a month! We now have Sussy Radish stickers and video podcasts available at certain levels! Your support keeps the show running and the bills paid so that we can keep making and publishing new episodes! Sign up for Patreon here: http://patreon.com/shakenanddisturbed Want Shaken and Disturbed merch? T-shirts, pillows, hoodies, phone cases, stickers and more are now available here: Shaken and Disturbed MERCH STORE And if you've already signed up for Patreon, thank you, Mom and Dad love you.