Podcasts about nmr

Nordiska motståndsrörelsen har länge varit den dominerande nazistiska gruppen i Norden. Förra sommaren fattade det amerikanska utrikesdepartementet ett historiskt beslut och klassade NMR som en terrorgrupp. Nu, ett år senare, har Expo granskat vad terrorklassningen inneburit för NMR i den nya Expo Insikt-rapporten ”I sanktionens skugga”. Hur har organisationens ekonomi och mobiliseringsförmåga påverkats? Har terrorklassningen lyckats slå ut organisationen, eller har de hittat nya vägar framåt? Gäster i studion är Expos researchers och utbildare Jonathan Leman och Morgan Finnsiö. Programledare: Erik Glaad --- Läs mer: Sammanfattningen av Expo Insikt-rapporten "I sanktionens skugga": https://expo.se/lar-dig-mer/publikationer/i-sanktionens-skugga/  Expos årsrapport över den svenska rasideologiska miljön 2024: https://expo.se/lar-dig-mer/publikationer/svensk-rasideologisk-miljo-2024/  Sammanfattning av Expo Insikt-rapporten "Högerextrem demografi": https://expo.se/lar-dig-mer/publikationer/lokal-hogerextrem-demografi/  Expo Guidar: Så har NMR påverkats av USA:s terrorklassning (Dalsbro, 2025): https://expo.se/nyhet/expo-guidar-sa-har-nmr-paverkats-av-usas-terrorklassning/  Expos samlade rapportering om NMR: https://expo.se/tag/nordiska-motstandsrorelsen-nmr/  Expo Insikt fördjupar olika trender och fenomen som Expo bedömer vara viktiga att känna till för dig som hanterar våldsbejakande extremism i din yrkesroll eller som är verksam inom akademin. Expo Insikt #1 - 2025 lanseras den 16 juni 2025. För att ta del av hela rapporten behöver du teckna en prenumeration. Expo behöver ditt stöd Bli poddvän här: https://expo.se/stod-expo/bli-poddvan/  Prenumerera på Expo: https://expo.se/tidskriften/prenumerera  --- Studio Expo ger dig som lyssnar fördjupningar om våra avslöjanden, mer om våra granskningar och analyser av högextrema tendenser. Varje vecka i din poddspelare! Expo är en religiöst och partipolitiskt obunden stiftelse. Vi har granskat och bevakat extremhögern sedan 1995 – för en levande demokrati där rasistiska idéer och organisationer saknar inflytande. Stöd vår verksamhet genom att bli månadsgivare eller swisha en slant till 123 271 02 59.

Audio FileGround Truths can also be found on Apple Podcasts, Spotify and YouTube.The UK is the world leader in human genomics, and laid the foundation for advancing medicine with the UK Biobank, Genomes England and now Our Future Health (w/ 5 million participants). Sir John Bell is a major force in driving and advising these and many other initiatives. After 22 years as the Regius Professor of Medicine at the University of Oxford he left in 2024 to be President of the Ellison Institute of Technology. Professor Bell has been duly recognized in the UK: knighted in 2015 and appointed Companion of Honor in 2023. In our conversation, you will get a sense for how EIT will be transformational for using A.I. and life science for promoting human health.Transcript with audio links Eric Topol (00:06):Hello, this is Eric Topol from Ground Truths. And I'm really delighted to welcome today, Sir John Bell who had an extraordinary career as a geneticist, immunologist, we'll talk about several initiatives he's been involved with during his long tenure at University of Oxford, recently became head of the Ellison Institute of Technology (EIT) in the UK. So welcome, John.Sir John Bell (00:30):Thanks, Eric. Thanks very much for having me.Eric Topol (00:34):Well, I think it's just extraordinary the contributions that you have made and continue to make to advance medicine, and I thought what we could do is get into that. I mean, what's interesting, you have had some notable migrations over your career, I think starting in Canada, at Stanford, then over as Rhodes Scholar in Oxford. And then you of course had a couple of decades in a very prestigious position, which as I understand was started in 1546 by King Henry VII, and served as the Regius Professor of Medicine at the University of Oxford. Do I have that right?Sir John Bell (01:11):It was actually Henry VIII, but you were close.Eric Topol (01:14):Henry VIII, that's great. Yeah. Okay, good. Well, that's a pretty notable professorship. And then of course in recent times you left to head up this pretty formidable new institute, which is something that's a big trend going on around the world, particularly in the US and we'll talk about. So maybe we can start with the new thing. Tell us more about the Ellison Institute of Technology (EIT), if you will.Sir John Bell (01:47):Yeah. So as you know, Larry Ellison has been one of the great tech entrepreneurs focused really on developing terrific databases over his career and through Oracle, which is the company that he founded. And Larry is really keen to try and give back something substantial to the world, which is based on science and technology. So he and I did quite a bit together over the Covid pandemic. He and I talked a lot about what we're doing and so on. He came to visit afterwards and he had, I think he decided that the right way to make his contributions would be to set up an institute that would be using the state-of-the-art science and technology with a lot of AI and machine learning, but also some of the other modern tools to address the major problems in healthcare, in food security, in green energy and climate change and in global governance.Sir John Bell (02:49):So anyway, he launched this about 18 months ago. He approached me to ask whether I would run it. He wanted to set it up outside Oxford, and he wanted to do something which is a bit different than others. And that is his view was that we needed to try and create solutions to these problems which are commercially viable and not all the solutions are going to be commercially viable, but where you can create those, you make them sustainable. So the idea is to make sure that we create solutions that people want to buy, and then if they buy them, you can create a sustainable solution to those issues. So we are actually a company, but we are addressing many of the same problems that the big foundations are addressing. And the big issues that you and I talk about in health, for example, are all on our list. So we're kind of optimistic as to where this will go and Larry's supporting the project and we're going to build out an institute here which will have about 5,000 people in it, and we'll be, I think a pretty exciting new addition to the science and technology ecosystem globally.Eric Topol (04:02):Well, I know the reverberations and the excitement is palpable and some of the colleagues I've spoken to, not just in England, but of course all over the world. So congratulations on that. It was a big move for you to leave the hardcore academics. And the other thing I wanted to ask you, John, is you had distinguished your career in immunology, in genetics, type 1 diabetes and other conditions, autoimmune conditions, and now you've really diversified, as you described with these different areas of emphasis at the new institute. Is that more fun to do it or do you have deputies that you can assign to things like climate change in other areas?Sir John Bell (04:50):Trust me, Eric, I'm not making any definitive decisions about areas I know nothing about, but part of this is about how do you set up leadership, run a team, get the right people in. And I have to say one of the really interesting things about the institute is we've been able to recruit some outstanding people across all those domains. And as you know, success is almost all dependent on people. So we're really pretty optimistic we're going to have a significant impact. And of course, we also want to take risks because not a lot of point in us doing stuff that everybody else is doing. So we're going to be doing some things that are pretty way out there and some of them will fail, so we are just going to get used to trying to make sure we get a few of them across the finish line. But the other thing is that, and you've experienced this too, you never get too old to learn. I mean, I'm sucking up stuff that I never thought I would ever learn about, which is fun actually, and really marvel.Eric Topol (05:55):It's fantastic. I mean, you've really broadened and it's great that you have the runway to get these people on board and I think you're having a big building that's under construction?Sir John Bell (06:07):Yeah, we've got the original building that Larry committed to is about 330,000 square feet of space. I mean, this is completely amazing, but we are of course to accommodate up to 5,000 people, we're going to need more than that. So we are looking at a much wider campus here that'll involve more than just that building. I think we'll end up with several million square feet of space by the time we're finished. So mean, it's a really big project, but we've already made progress in some domains to try and get projects and the beginnings of companies on the road to try and solve some of the big problems. So we're quite excited about it.Eric Topol (06:49):Now you, I assume it's pretty close to Oxford, and will you have some kind of inter interactions that are substantial?Sir John Bell (06:58):Yeah, so the university's been terrific about this actually, because of course most universities would say, well, why don't you do it inside the university and just give us the money and it'll all be fine. So of course Larry. Larry wasn't born yesterday, so I said, well, thank you very much, but I think we'll probably do this nearby. But the university also realized this is a really exciting opportunity for them and we've got a really good relationship with them. We've signed an agreement with them as to who will work where. We've agreed not to steal a lot of their staff. We're going to be bringing new people into the ecosystem. Some of the university people will spend some time with us and sometime in the university, so that will help. But we're also bringing quite a few new people into the setting. So the university has been really positive. And I think one of the things that's attractive to the university, and you'll be familiar with this problem in the UK, is that we're quite good. The discovery science here is pretty good.Sir John Bell (08:06):And we do startups now at scale. So Oxford does lots of little startup companies in the biotech space and all the rest of it, but we never scale any of these companies because there isn't the depth of capital for scaling capital to get these things scaled. And so, in a way what we're trying to do here at Ellison actually avoids that problem because Larry knows how to scale companies, and we've got the financial support now. If we have things that are really successful, we can build the full stack solution to some of these problems. So I think the university is really intrigued as to how we might do that. We're going to have to bring some people in that know how to do that and build billion dollar companies, but it's sufficiently attractive. We've already started to recruit some really outstanding people. So as a way to change the UK system broadly, it's actually quite a good disruptive influence on the way the thing works to try and fix some of the fundamental problems.Eric Topol (09:07):I love that model and the ability that you can go from small startups to really transformative companies have any impact. It fits in well with the overall objectives, I can see that. The thing that also is intriguing regarding this whole effort is that in parallel we've learned your influence. The UK is a genomics world leader without any question and no coincidence that that's been your area of emphasis in your career. So we've watched these three initiatives that I think you were involved in the UK Biobank, which has had more impact than any cohort ever assembled. Every day there's another paper using that data that's coming out. There's Genomes England, and then now Our Future Health, which a lot of people don't know about here, which is well into the 5 million people enrollment. Can you tell us about, this is now 15 years ago plus when these were started, and of course now with a new one that's the biggest ever. What was your thinking and involvement and how you built the UK to be a world leader in this space?Sir John Bell (10:26):So if you turn the clock back 20 years, or actually slightly more than 25 years ago, it was clear that genomics was going to have a play. And I think many of us believed that there was going to be a genetic element to most of the major common disease turn out to be true. But at the time, there were a few skeptics, but it seemed to us that there was going to be a genetic story that underpinned an awful lot of human disease and medicine. And we were fortunate because in Oxford as you know, one of my predecessors in the Regius job was Richard Doll, and he built up this fantastic epidemiology capability in Oxford around Richard Peto, Rory Collins, and those folks, and they really knew how to do large scale epidemiology. And one of the things that they'd observed, which is it turns out to be true with genetics as well, is a lot of the effects are relatively small, but they're still quite significant. So you do need large scale cohorts to understand what you're doing. And it was really Richard that pioneered the whole thinking behind that. So when we had another element in the formula, which was the ability to detect genetic variation and put that into the formula, it seemed to me that we could move into an era where you could set up, again, large cohorts, but build into the ability to have DNA, interrogate the DNA, and also ultimately interrogate things like proteomics and metabolomics, which were just in their infancy at that stage.Sir John Bell (12:04):Very early on I got together because I was at that stage at the Nuffield Chair of Medicine, and I got together, Rory and Richard and a couple of others, and we talked a little bit about what it would look like, and we agreed that a half a million people late to middle age, 45 and above would probably over time when you did the power calculations, give you a pretty good insight in most of the major diseases. And then it was really a question of collecting them and storing the samples. So in order to get it funded at the time I was on the council of the MRC and George Radda, who you may remember, was quite a distinguished NMR physiologist here. He was the chief executive of the MRC. So I approached him and I said, look, George, this would be a great thing for us to do in the UK because we have all the clinical records of these people going back for a decade, and will continue to do that.Sir John Bell (13:01):Of course, we immediately sent it out to a peer review committee in the MRC who completely trashed the idea and said, you got to be joking. So I thought, okay, that's how that lasted. And I did say to George, I said, that must mean this is a really good idea because if it had gone straight through peer review, you would've known you were toast. So anyway, I think we had one more swing at peer review and decided in the end that wasn't going to work. In the end, George to his credit, took it to MRC council and we pitched it and everybody thought, what a great idea, let's just get on and do it. And then the Wellcome came in. Mark Walport was at the Wellcome at the time, great guy, and did a really good job at bringing the Wellcome on board.Sir John Bell (13:45):And people forget the quantum of money we had to do this at the time was about 60 million pounds. I mean, it wasn't astonishly small. And then of course we had a couple of wise people who came in to give us advice, and the first thing they said, well, if you ever thought you were really going to be able to do genetics on 500,000 people, forget it. That'll never work. So I thought, okay, I'll just mark that one out. And then they said, and by the way, you shouldn't assume you can get any data from the health service because you'll never be able to collect clinical data on any of these people. So I said, yeah, yeah, okay, I get it. Just give us the money and let us get on. So anyway, it's quite an interesting story. It does show how conservative the community actually is for new ideas.Sir John Bell (14:39):Then I chaired the first science committee, and we decided about a year into it that we really needed the chief executive. So we got Rory Collins to lead it and done it. I sat on the board then for the next 10 years, but well look, it was a great success. And as you say, it is kind of the paradigm for now, large genetic epidemiology cohorts. So then, as you know, I advise government for many years, and David Cameron had just been elected as Prime Minister. This was in about 2010. And at the time I'd been tracking because we had quite a strong genomics program in the Wellcome Trust center, which I'd set up in the university, and we were really interested in the genetics of common disease. It became clear that the price of sequencing and Illumina was now the clear leader in the sequencing space.Sir John Bell (15:39):But it was also clear that Illumina was making significant advances in the price of sequencing because as you remember, the days when it cost $5,000 to do a genome. Anyway, it became clear that they actually had technology that gets you down to a much more sensible price, something like $500 a genome. So I approached David and I said, we are now pretty sure that for many of the rare diseases that you see in clinical practice, there is a genetic answer that can be detected if you sequenced a whole genome. So why don't we set something up in the NHS to provide what was essentially the beginnings of a clinical service to help the parents of kids with various disabilities work out what's going on, what's wrong with their children. And David had had a child with Ohtahara syndrome, which as you know is again, and so David was very, he said, oh God, I'll tell you the story about how awful it was for me and for my wife Samantha.Sir John Bell (16:41):And nobody could tell us anything about what was going on, and we weren't looking for a cure, but it would've really helped if somebody said, we know what it is, we know what the cause is, we'll chip away and maybe there will be something we can do, but at least you know the answer. So anyway, he gave us very strong support and said to the NHS, can you please get on and do it? Again massive resistance, Eric as you can imagine, all the clinical geneticists said, oh my God, what are they doing? It's complete disaster, dah, dah, dah. So anyway, we put on our tin hats and went out and got the thing going. And again, they did a really good job. They got to, their idea was to get a hundred thousand genomes done in a reasonable timeframe. I think five years we set ourselves and the technology advance, people often underestimate the parallel development of technology, which is always going on. And so, that really enabled us to get that done, and it still continues. They're doing a big neonatal program at the moment, which is really exciting. And then I was asked by Theresa May to build a life science strategy because the UK, we do this stuff not as big and broad as America, but for a small country we do life sciences pretty well.Eric Topol (18:02):That's an understatement, by the way. A big understatement.Sir John Bell (18:04):Anyway, so I wrote the strategies in 2017 for Theresa about what we would do as a nation to support life sciences. And it was interesting because I brought a group of pharma companies together to say, look, this is for you guys, so tell us what you want done. We had a series of meetings and what became clear is that they were really interested in where healthcare was going to end up in the next 20 years. And they said, you guys should try and get ahead of that wave. And so, we agreed that one of the domains that really hadn't been explored properly, it was the whole concept of prevention.Sir John Bell (18:45):Early diagnosis and prevention, which they were smart enough to realize that the kind of current paradigm of treating everybody in the last six months of life, you can make money doing that, there's no doubt, but it doesn't really fix the problem. And so, they said, look, we would love it if you created a cohort from the age of 18 that was big enough that we could actually track the trajectories of people with these diseases, identify them at a presymptomatic stage, intervene with preventative therapies, diagnose diseases earlier, and see if we could fundamentally change the whole approach to public health. So we anyway, went back and did the numbers because of course at much wider age group, a lot of people don't get at all sick, but we thought if we collected 5 million people, we would probably have enough. That's 10% of the UK adult population.Sir John Bell (19:37):So anyway, amazingly the government said, off you go. We then had Covid, which as you know, kept you and I busy for a few years before we could get back to it. But then we got at it, and we hired a great guy who had done a bit of this in the UAE, and he came across and we set up a population health recruitment structure, which was community-based. And we rapidly started to recruit people. So we've now got 2.9 million people registered, 2.3 million people consented, and we've got blood in the bank and all the necessary data including questionnaire data for 1.5 million people growing up. So we will get to 5 million and it's amazing.Eric Topol (20:29):It is. It really is, and I'm just blown away by the progress you've made. And what was interesting too, besides you all weren't complacent about, oh, we got this UK Biobank and you just kept forging ahead. And by the way, I really share this importance of finally what has been a fantasy of primary prevention, which never really achieved. It's always, oh, after a heart attack. But that's what I wrote about in the Super Agers book, and I'll get you a copy.Sir John Bell (21:02):No, I know you're a passionate believer in this and we need to do a lot of things. So we need to work out what's the trial protocol for primary prevention. We need to get the regulators on board. We've got to get them to understand that we need diagnostics that define risk, not disease, because that's going to be a key bit of what we're going to try and do. And we need to understand that for a lot of these diseases, you have to intervene quite early to flatten that morbidity curve.Eric Topol (21:32):Yeah, absolutely. What we've learned, for example, from the UK Biobank is not just, of course the genomics that you touched on, but the proteomics, the organ clocks and all these other layers of data. So that gets me to my next topic, which I know you're all over it, which is AI.Eric Topol (21:51):So when I did the NHS review back in 2018, 2019, the group of people which were amazing that I had to work with no doubt why the UK punches well beyond its weight. I had about 50 people, and they just said, you know what? Yeah, we are the world leaders in genomics. We want to be the world leader in AI. Now these days you only hear about US and China, which is ridiculous. And you have perhaps one of the, I would say most formidable groups there with Demis and Google DeepMind, it's just extraordinary. So all the things that the main foci of the Ellison Institute intersect with AI.Sir John Bell (22:36):They do. And we, we've got two underpinning platforms, well actually three underpinning platforms that go across all those domains. Larry was really keen that we became a real leader in AI. So he's funded that with a massive compute capacity. And remember, most universities these days have a hard time competing on compute because it's expensive.Eric Topol (22:57):Oh yeah.Sir John Bell (22:58):So that is a real advantage to us. He's also funded a great team. We've recruited some people from Demis's shop who are obviously outstanding, but also others from around Europe. So we really, we've recruited now about 15 really outstanding machine learning and AI people. And of course, we're now thinking about the other asset that the UK has got, and particularly in the healthcare space is data. So we do have some really unique data sets because those are the three bits of this that you need if you're going to make this work. So we're pretty excited about that as an underpinning bit of the whole Ellison Institute strategy is to fundamentally underpin it with very strong AI. Then the second platform is generative biology or synthetic biology, because this is a field which is sort of, I hesitate to say limped along, but it's lacked a real focus.Sir John Bell (23:59):But we've been able to recruit Jason Chin from the LMB in Cambridge, and he is one of the real dramatic innovators in that space. And we see there's a real opportunity now to synthesize large bits of DNA, introduce them into cells, microbes, use it for a whole variety of different purposes, try and transform plants at a level that people haven't done before. So with AI and synthetic biology, we think we can feed all the main domains above us, and that's another exciting concept to what we're trying to do. But your report on AI was a bit of a turning point for the UK because you did point out to us that we did have a massive opportunity if we got our skates, and we do have talent, but you can't just do it with talent these days, you need compute, and you need data. So we're trying to assemble those things. So we think we'll be a big addition to that globally, hopefully.Eric Topol (25:00):Yeah. Well that's another reason why I am so excited to talk to you and know more about this Ellison Institute just because it's unique. I mean, there are other institutes as like Chan Zuckerberg, the Arc Institute. This is kind of a worldwide trend that we're seeing where great philanthropy investments are being seen outside of government, but none have the computing resources that are being made available nor the ability to recruit the AI scientists that'll help drive this forward. Now, the last topic I want to get into with you today is one that is where you're really grounded in, and that's the immune response.Eric Topol (25:43):So it's pretty darn clear now that, well, in medicine we have nothing. We have the white cell neutrophil to lymphocyte ratio, what a joke. And then on the other hand, we can do T and B cell sequencing repertoires, and we can do all this stuff, autoantibody screens, and the list goes on and on. How are we ever going to make a big dent in health where we know the immune system is such a vital part of this without the ability to check one's immune status at any point in time in a comprehensive way? What are your thoughts about that?Sir John Bell (26:21):Yeah, so you seem to be reading my mind there. We need to recruit you over here because I mean, this is exactly, this is one of our big projects that we've got that we're leaning into, and that is that, and we all experienced in Covid the ins and outs of vaccines, what works, what doesn't work. But what very clear is that we don't really know anything about vaccines. We basically, you put something together and you hope the trial works, you've got no intermediate steps. So we're building a really substantial immunophenotyping capability that will start to interrogate the different arms of the immune response at a molecular level so that we can use a combination of human challenge models. So we've got a big human challenge model facility here, use human challenge models with pathogens and with associated vaccines to try and interrogate which bits of the immune response are responsible for protection or therapy of particular immunologically mediated diseases or infectious diseases.Sir John Bell (27:30):And a crucial bit to that. And one of the reasons people have tried this before, but first of all, the depth at which you can interrogate the immune system has changed a lot recently, you can get a lot more data. But secondly, this is again, where the AI becomes important because it isn't going to be a simple, oh, it's the T-cell, it's going to be, well, it's a bit of the T cells, but it's also a bit of the innate immune response and don't forget mate cells and don't forget a bit of this and that. So we think that if we can assemble the right data set from these structured environments, we can start to predict and anticipate which type of immune response you need to stimulate both for therapy and for protection against disease. And hopefully that will actually create a whole scientific foundation for vaccine development, but also other kinds of immune therapy and things like cancer and potentially autoimmune disease as well. So that's a big push for us. We're just busy. The lab isn't set up. We've got somebody to run the lab now. We've got the human challenge model set up with Andy Pollard and colleagues. So we're building that out. And within six months, I think we'll be starting to collect data. So I'm just kind of hoping we can get the immune system in a bit more structured, because you're absolutely right. It's a bit pin the tail on the donkey at the moment. You have no idea what's actually causing what.Eric Topol (29:02):Yeah. Well, I didn't know about your efforts there, and I applaud that because it seems to me the big miss, the hole and the whole story about how we're going to advanced human health and with the recent breakthroughs in lupus and these various autoimmune diseases by just targeting CD19 B cells and resetting like a Ctrl-Alt-Delete of their immune system.Sir John Bell (29:27):No, it's amazing. And you wouldn't have predicted a lot of this stuff. I think that means that we haven't really got under the skin of the mechanistic events here, and we need to do more to try and get there, but there's steady advance in this field. So I'm pretty optimistic we'll make some headway in this space over the course of the next few years. So we're really excited about that. It's an important piece of the puzzle.Eric Topol (29:53):Yeah. Well, I am really impressed that you got all the bases covered here, and what a really exhilarating chance to kind of peek at what you're doing there. And we're going to be following it. I know I'm going to be following it very closely because I know all the other things that you've been involved with in your colleagues, big impact stuff. You don't take the little swings here. The last thing, maybe to get your comment, we're in a state of profound disruption here where science is getting gutted by a madman and his henchmen, whatever you want to call it, which is really obviously a very serious state. I'm hoping this is a short term hit, but worried that this will have a long, perhaps profound. Any words of encouragement that we're going to get through this from the other side of the pond?Sir John Bell (30:52):Well, I think regardless of the tariffs, the scientific community are a global community. And I think we need to remember that because our mission is a global mission, and we need to lean into that together. First of all, America is such a powerhouse of everything that's been done scientifically in the human health domain. But not only that, but across all the other domains that we work in, we can't really make the kind of progress that we need to without America being part of the agenda. So first of all, a lot of sympathy for you and your colleagues. I know it must be massively destabilizing for you, not be confident that the things that work are there to help you. But I'm pretty confident that this will settle down. Most of the science is for, well, all the science is really for public good, and I think the public recognizes it and they'll notice if it's not being prosecuted in the way that it has to be. And the global science community cannot survive without you. So we're all leaning in behind you, and I hope it will settle. One of my worries is that these things take years to set up and literally hours or minutes to destroy. So we can't afford to take years to set them back up again. So we do need to be a bit careful about that, but I still have huge confidence in what you guys can achieve and we're all behind you.Eric Topol (32:37):Well, that's really helpful getting some words of wisdom from you there, John. So this has been terrific. Thanks so much for joining, getting your perspective on what you're doing, what's important is so essential. And we'll stay tuned for sure.Sir John Bell (32:59):And come and visit us at the EIT, Eric. We'd be glad to see you.*******************************Some of the topics that John and I discussed—immunology, A.I., genomics, and prevention—are emphasized in my new book SUPER AGERS. A quick update: It will have a new cover after making the New York Times Bestseller list and is currently ranked #25 for all books on Amazon. Thanks to so many of you for supporting the book!Here are a few recent podcasts:Dax Shepard: Dr. Mike Sanjay Gupta ***********************Thanks for reading and subscribing to Ground Truths.If you found this interesting please share it!That makes the work involved in putting these together especially worthwhile.All content on Ground Truths— newsletters, analyses, and podcasts—is free, open-access.Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. Get full access to Ground Truths at erictopol.substack.com/subscribe

Dr. Martin answers questions sent in by our listeners. Some of today's topics include: Over-the-counter pain meds Edema & swollen ankles Low doses of statin drugs NAD supplements Floaters in eyes Preparing for pulmonary test Zinc & Alzheimer's NMR lipoprofile tests  

Daryn gives her review of both Cowboy Carter and Cotton Candy KitKats. John wants Daryn to see the new Marvel movie (what else is new!). Starting this week we are releasing NMR and our weekly cases in alternate weeks! Sign up for Patreon to get early access to EVERYTHING so you will never be late to the party! Watch and listen to this and every other episode several days early on Patreon! Patreon members can join us during our live recordings, comment on the case, participate in polls and get shout outs! Join for as little as $5 a month right here! Want Shaken and Disturbed merch? T-shirts, pillows, hoodies, phone cases, stickers and more are now available here: Shaken and Disturbed MERCH STORE Follow John on Twitter @jthrasher, Instagram @jthrasher and TikTok @johnthrasher Follow Daryn on Twitter @CarpeDaryn and Instagram @CarpeDaryn Join the official Shake and Disturbed Fans Facebook Group here! SUBSCRIBE TO SHAKEN AND DISTURBED ON YOUTUBE!

In this episode, Seth Tandett brings back Dr. Jon Belkowitz to unpack a powerful but often misunderstood tool in the concrete world—petrography. From diagnosing floor failures to proactively optimizing mix designs, Dr. Jon explains how petrography gives contractors, suppliers, and engineers a microscopic advantage. Whether you're battling ASR or just curious about those weird white streaks on your concrete, this episode is for you.

NMRThe National Johne's Management Plan Please note: The information provided during this podcast has been prepared for general informational purposes only and does not constitute advice. The information must not be relied upon for any purpose and no representation or warranty is given as to its accuracy, completeness or otherwise. Any reference to other organisations, businesses or products during the podcast are not endorsements or recommendations of Dairy Consulting Ltd or its affiliated companies. The views of the presenter are personal and may not be the views of Dairy Consulting Ltd. The contents of this podcast are the copyright of Dairy Consulting Ltd.

Lab test for health enthusiasts The yearly lab testing ordered by most doctors may not provide the full picture of your state of health. Cholesterol testing through NMR, measuring apolipoprotein B, and testing urinary hormone metabolites and the microbiome provide a deep dive into your disease risk. On this episode of Live Foreverish, Drs. Mike and Crystal review these advanced tests and more! #LELearn

Minister for Further and Higher Education, Research, Innovation and Science, James Lawless TD, has today announced a €17.7 million investment in nine research infrastructure projects through Research Ireland's Research Infrastructure Programme. The awards will contribute to the advancement of high-quality and high-impact research activities across Ireland. Announcing the funding, Minister Lawless commented: "This targeted investment in research infrastructure will help to future-proof the conducting of high-quality research endeavours across our higher education institutions and in a wide range of disciplines. It is important for researchers to be equipped with the innovative tools and the conducive environments that can help deliver research excellence and impact." In welcoming the announcement, Celine Fitzgerald, Interim Chief Executive of Research Ireland, said: "The Research Infrastructure Programme supports the research community in building and sustaining cutting-edge infrastructure to accomplish high-quality, impactful, and innovative research. The programme encourages partnerships and collaboration between different cohorts of researchers in Ireland, across academia and enterprise." Nine Irish research infrastructure projects The nine funded projects are: Coastal & Offshore ASV (Autonomous Surface Vehicle), University of Limerick, led by Prof. Gerard Dooly, aims to acquire a coastal and offshore autonomous surface vehicle (ASV) with a length of 9 meters and a range of 2500 nautical miles. This will enhance Ireland's marine science capabilities, bridge data gaps, and improve our understanding of ocean habitats. (€1,851,784) Cryo Electron Microscopy Unit National Platform, University College Dublin, led by Prof. Oliver Blacque, will establish a cryo-EM unit for high-resolution 3D visualisation of biological structures, aiding various biomedical research applications. (€3,749,322) NMR Centre of Expertise, Trinity College Dublin, led by Prof. Mathias Senge, will provide advanced NMR techniques for chemistry research, including a multi-channel 600MHz NMR and a 400MHz instrument for high-throughput analyses. (€2,649,497) Photon Counting CT for Cardiovascular and Oncology Research, Trinity College Dublin, led by Prof. James Meaney, will expand imaging capabilities with a Photon-counting CT scanner for advanced medical imaging in oncology and cardiovascular research. (€2,721,339) National Enteric Methane Mitigation Testbed, Teagasc, led by Dr Stephen Butler, will develop strategies to reduce methane emissions from ruminant animals, contributing to climate change mitigation. (€1,983,502) Characterising Earth Materials using Multi-Sensor Core Logger Analysis (Earth SCAn), University College Dublin, led by Prof. Peter Haughton, will advance the characterisation of Earth materials for interdisciplinary research into climate change, energy, and geohazards. (€600,113) Advanced Material Characterisation and Imaging Platform, Dublin City University, led by Dr Karsten Fleischer, will enhance material analysis capabilities with X-ray photoelectron spectroscopy (XPS) for various applications in ICT, energy, and medical devices. (€2,251,897) C-Trap: A Dynamic Single Molecule Platform for Chemical Biology and Biophysics, Dublin City University, led by Prof. Andrew Kellett, will enable single-molecule analysis for understanding molecular mechanisms of diseases, aiding biopharmaceutical and therapeutic research. (€948,901) Automated X-ray Photoelectron Spectroscopy (XPS), University College Dublin, led by Prof. Eoin Casey, will replace aging XPS equipment to enhance surface analysis capabilities for various research and industry applications. (€986,952) The awardees are from the following research bodies: University of Limerick (UL), University College Dublin (UCD), Trinity College Dublin (TCD), Teagasc, and Dublin City University (DCU). See more breaking stories here.

What if your body was sending warning signals years before disease struck—and you could actually see them? That's exactly what comprehensive blood testing offers, yet most people avoid or minimize the importance of regular lab work until symptoms appear. In this eye-opening conversation, fitness coach Derrick Wellock and his wife Cassie, a physician assistant who recently opened Vertical Primary Care within Double Edge Fitness, share their expertise on using blood work as your body's early warning system.Cassie explains how standard lab ranges reflect the average population rather than optimal health, and why "normal" results might still warrant attention, especially for those seeking longevity and peak performance. The couple dives deep into cholesterol testing, revealing why an advanced NMR panel that measures particle size offers far more valuable information than standard lipid profiles. Derrick transparently shares his personal journey with high cholesterol and how coconut oil—touted as healthy in fitness circles—sent his numbers "bonkers" virtually overnight.The discussion challenges common misconceptions about carbohydrates and insulin sensitivity, with both hosts explaining how strategically incorporating quality carbs actually improved Derrick's blood glucose levels. They also tackle hormone optimization for both men and women, providing a nuanced view of testosterone replacement therapy beyond the oversimplified approaches offered by many hormone clinics.Whether you're a fitness enthusiast who assumes external health equals internal health, someone avoiding medical care, or simply curious about preventative medicine, this episode offers practical guidance for using blood work as a powerful tool in your health journey. As Derrick aptly puts it: "Blood work is like your car's dashboard—it tells you when to act before the engine fails."Ready to take control of your health journey? Schedule those labs, establish your baseline, and discover what's really happening beneath the surface. The insights could add years of quality life to your future.Follow us on Instagram here! https://www.instagram.com/doubleedgefitness/

The Big One Hundred! With WYKD! Westway Yoga Kolectiv Dana also..... WICKED! WYKD BELIEVES IN A UNIFIED COMMUNITY AND THE HEALING BENEFITS OF YOGA FOR EVERYONE! I am so thrilled that my Nmr 100 is with these beautiful people behind WYKD a wonderful community yoga and mindfulness project from London! I have been honoured and blessed to have played a small part as a teacher within this project and now i am able to share the wonderful work of WYKD with the world! In this episode i speak with founders Lauren and Keri, two soul sisters i hold close to my heart! We discuss: What is WYKD and where did it all begin? The importance of the project and projects alike. How to make yoga and mindfulness accessible to everyone. Designing a schedule which is accessible to all ages, bodies and backgrounds of the community.The principles of DIVERSITY and INCLUSIVITY lie at the heart of this project, how to go about that. Music, a love for music and how music also CONNECTS different communities. Have a listen, share and SUPPORT them! https://www.wykd.uk/supportSHOWNOTES: https://www.wykd.uk/INSTAGRAM: wykd_ldn 

I år är det 100 år sedan det första svenska nazistpartiet bildades. Trots vetskapen om nazismens fruktansvärda konsekvenser har nya anhängare fortsatt att attraheras av dess rasism och antidemokratiska idéer. 100 år av obruten nazistisk organisering. Det är en brokig historia fylld av våld, terror och gatuaktivism. Men även valsatsningar och entreprenörskap. Mängder av partier och organisationer har bildats och försvunnit. Det har varit otaliga interna strider och fraktionsbildningar, men även återkommande enhetsförsök. Expo kommer i fyra avsnitt att berätta om den här heterogena rörelsens utveckling och olika faser från de första partibildningarna till dagens slagsmålsklubbar.   Vi har nu kommit fram till 2000-talet. Ett mord i Salem som får stora delar av den svenska nazistmiljön att enas och under det nya millenniets första decennium genomförs flera samlande demonstrationer innan konflikter och interna strider återigen sätter stopp för sammanhållningen.  Det fjärde och avslutande avsnittet i serien om 100 år av svensk nazism handlar om vår samtida nazistiska historia — där det parallellt med partisatsningar går att se hur lösare nätverk och lokala aktivistgrupper slår igenom. Det är en trendkänslig, internationellt uppkopplad och snabbt skiftande miljö som jämte nazismen ger plats för identitärer, nyfascister, fria nationalister, realister, alt-right-aktivister, medborgarjournalister och aktivklubbar. Och återigen är våldet den nazistiska idévärldens följeslagare — med bombattentat, mord och skoldåd.  Hur kan vi förstå det myller av organisationsformer vi ser växa fram under 2000-talet? Hur utnyttjar extremhögern den digitala revolutionen? Och hur påverkar miljöns nu nästan 100 åriga historia den samtida nazismen? Vi är framme vid smörgåsbordsnazismen och de så kallade ensamagerande terroristernas epok. Gäster i studion är Daniel Poohl, vd på Expo och Anders Dalsbro, reporter på Expo. Programledare: Anna Fröjd --- Läs mer: Studio Expo: 100 år av svensk nazism – Del 1 av 4: Pionjärerna https://expo.se/podcasts/100-ar-av-svensk-nazism-pionjarerna/  Studio Expo: 100 år av svensk nazism – Del 2 av 4: Övervintrarna https://expo.se/podcasts/100-ar-av-svensk-nazism-overvintrarna/ Studio Expo: 100 år av svensk nazism – del 3 av 4: Raskrigarna https://expo.se/podcasts/100-ar-av-svensk-nazism-raskrigarna/  #4-2023 Tidskriften Expo, 100 år av svensk nazism: https://expo.se/lar-dig-mer/tidskriften/hundra-ar-av-svensk-nazism/  Expo wiki – Nationalsocialistisk front (NSF): https://expo.se/lar-dig-mer/wiki/nationalsocialistisk-front-nsf/  Expo wiki – Nordiska förbundet: https://expo.se/lar-dig-mer/wiki/nordiska-forbundet/  Expo wiki – Nationaldemokraterna: https://expo.se/lar-dig-mer/wiki/nationaldemokraterna/  Expo wiki – Nordiska motståndsrörelsen (NMR): https://expo.se/lar-dig-mer/wiki/nordiska-motstandsrorelsen-nmr/  Expo wiki – Alt-right: https://expo.se/lar-dig-mer/wiki/alt-right-rorelsen/    Expo behöver ditt stöd Bli poddvän här: https://expo.se/stod-expo/bli-poddvan/ Prenumerera på Expo: https://expo.se/tidskriften/prenumerera  --- Studio Expo ger dig som lyssnar fördjupningar om våra avslöjanden, mer om våra granskningar och analyser av högextrema tendenser. Varje vecka i din poddspelare! Expo är en religiöst och partipolitiskt obunden stiftelse. Vi har granskat och bevakat extremhögern sedan 1995 – för en levande demokrati där rasistiska idéer och organisationer saknar inflytande.

I Studion: Fredrik Söderholm, Daniel Gilbert, Sebastian Mattsson, Siri Bernhardsson, August BohlinMåndag 9 December!Sebastian Mattson & Daniel Gilbert flankerar dagen till ära! Äntligen: Pengaregn över Gilbert! I patreon-timmen: Mattssons massaker om arketypen: rasse moralpanik-kärringarna och gangsterapen! Apropå Assad-regimens fall: Vilken politikers palats hade man helst plundrat? Gott snack-chatt-profilen, tatueraren, konstnären och OF-kreatören Siri Bernardsson om att sälja sex på internet och resan med Linda Skugge till Berlin! Daniel Gilberts buktalar-kompis castades på Danmark-färja och fick showa för Kim Jong Ill Siri öppnar om den såriga relationenen mellan Gott snack-Chatten och Fredrik! I eftersnacket för 100 kronors patrons!Varför blev Siri Sverigedemokrat och varför kuppade NMR hennes tafs-vakt-initiativ? God morgon fina ni!Hela avsnittet finns på patreon.com/gottsnackSupport till showen http://supporter.acast.com/gott-snack-med-fredrik-soderholm. Hosted on Acast. See acast.com/privacy for more information.

I Studion: Fredrik Söderholm, Daniel Gilbert, Sebastian Mattsson, Siri Bernhardsson, August BohlinDel 2. Måndag 9 December!Sebastian Mattson & Daniel Gilbert flankerar dagen till ära! Äntligen: Pengaregn över Gilbert! I patreon-timmen: Mattssons massaker om arketypen: rasse moralpanik-kärringarna och gangsterapen! Apropå Assad-regimens fall: Vilken politikers palats hade man helst plundrat? Gott snack-chatt-profilen, tatueraren, konstnären och OF-kreatören Siri Bernardsson om att sälja sex på internet och resan med Linda Skugge till Berlin! Daniel Gilberts buktalar-kompis castades på Danmark-färja och fick showa för Kim Jong Ill Siri öppnar om den såriga relationenen mellan Gott snack-Chatten och Fredrik! I eftersnacket för 100 kronors patrons!Varför blev Siri Sverigedemokrat och varför kuppade NMR hennes tafs-vakt-initiativ? God morgon fina ni!Hela avsnittet finns på patreon.com/gottsnackSupport till showen http://supporter.acast.com/gott-snack-med-fredrik-soderholm. Hosted on Acast. See acast.com/privacy for more information.

Race Oncology Ltd (ASX:RAC, OTC:RAONF) CEO Daniel Tillett joins Proactive's Tylah Tully to discuss the FTO drug discovery program the company has concluded at Monash University's Fragment Platform (MFP). The program successfully identified 39 molecular candidates (‘hits') that bind specifically to the m6A RNA demethylase protein, FTO. These findings were validated using NMR spectroscopy and surface plasmon resonance. The program leverages NMR fragment screening to discover drug-like molecules that can regulate protein activity outside the enzyme's active site, offering an alternative to traditional high-throughput screening. The identified FTO-binding chemical scaffolds create opportunities for the development of patentable, first-in-class drugs targeting the m6A RNA epigenetic pathway. RNA epigenetics dysregulation, involving proteins like FTO, is linked to various cancers and metabolic diseases. However, selective inhibition of FTO is challenging due to structural similarities with related proteins in the ALKBH family. Race's use of Monash's curated chemical fragment library enabled the identification of unique FTO-binding structures. Race plans a ‘hit-to-lead' campaign to refine these fragments into lead drug candidates, focusing on improving potency, selectivity, toxicity profiles, and metabolic properties. The company is currently evaluating whether to proceed with this resource-intensive phase. #ProactiveInvestors #RaceOncology, #ASX, #RNAEpigenetics, #DrugDiscovery, #CancerTherapies, #FTOProtein, #OncologyResearch, #Biotechnology, #NMRScreening, #Epigenetics, #RNARegulation, #PharmaceuticalInnovation, #CancerDrugs, #MetabolicDiseases, #MonashUniversity, #MedicinalChemistry, #CancerResearch, #TargetedTherapies, #PatentableDrugs, #BiotechInvestment

Jofi rapporterar vad veckans vikarie Felicia ”Back from the dead” Jackson gjort sen sist, veckans vikarie Felicia ”Back from the dead” Jackson rapporterar vad SD gjort med skolmat I Uddevalla och Armann rapporterar vad NMR utsatts för av dom som styr USA och bankerna. Allt detta och ännu en bomb på Jofis gata i veckans avsnitt av DIN ENDA NYHETSKÄLLA. Köp biljetter till Under Jords höstsäsong  som har premiär nästa vecka via https://underjord.nu/. Stötta denna podden ekonomiskt på https://www.patreon.com/mandag så får du dessutom tillgång till massa Patreon-exklusivt material. Köp även biljetter till Ina och Petrinas show PetrINA via https://inaochpetrina.se och till Armanns show via https://linktr.ee/armannh. Bor du i Stockholm eller Uppsala kan du se Jofi köra standup på Oslipat denna veckan, biljetter till det hittar du via https://www.oslipat.com

In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Molly Atkinson, Assistant Professor of Chemistry at the University of North Texas in Denton, TX, and her graduate student David Hamilton. Atkinson and Hamilton are experts in Chemistry Education Research (CER), and they recently published a paper discussing results of a survey of bachelors-level chemists working in industry that asked them “What does industry want new chemists to know?”. The paper, published earlier this year in the Journal of Chemical Education, generated quite a lot of buzz on analytical chemistry social media. In the conversation we talk about highlights from the article, and touch on potential future work that could fill in knowledge gaps identified by the first survey. The survey revealed some trends that will be familiar to readers of LCGC Magazine. For example, the surveyed chemists indicated that liquid and gas chromatography are two of the top five most important instrumental techniques that new chemists entering industry should know how to use. On the other hand, the survey also revealed some surprising results - for example, nuclear magnetic resonance (NMR) spectroscopy was not in the top-five instrumental techniques, despite that NMR occupies a prominent position in most undergraduate chemistry curricula in the United States. Finally, the guests and co-hosts discuss a bit about how Chemistry Education Research “works”, for listeners who are less familiar with this discipline than other more traditional research areas.

Gäster: Sebastian Järpehag, Christer Svensson, Jonathan Tengwall, Jonas Dillner För 90SEK/mån får du 5 avsnitt i veckan: 4 Vanliga AMK MORGON + AMK FREDAG med Isak Wahlberg www.patreon.com/amkmorgon STORY HOTEL AMK Morgons lyssnare har 30% rabatt på samtliga rumskategorier. Patreons har 40% rabatt på samtliga rumskategorier För att boka, gå in på hyatt.com och ange koden 165414 under "Corporate or Group Code" (viktigt att inte välja annan typ av rabattkod). UPPTÄCKA Köp ett fint mikroskop för barn! Upptäcka är en fin liten produkt som låter ditt barn från 5år och uppåt, upptäcka världen. Ett lättanvänt, portabelt mikroskop med 20 till 40 gångers förstoring och en 2 megapixel kamera som kan fånga både bilder och video på den lilla skärmen. En perfekt present till ditt barn nu inför sommarlovet. www.upptackatoys.com/amk eller discount koden “amk” i checkout (inte cart) så får du rabatt på ditt köp PRE-SAVEA AGNES NYA LÅT ”ELDEN” https://ninetone.link/elden Relevanta länkar: …Oasis https://www.aftonbladet.se/nojesbladet/a/xmJOrj/oasis-aterforenas-2025-hit-kommer-turnen https://www.expressen.se/noje/oasis-aterforenas/ https://en.wikipedia.org/wiki/Oasis_(band) https://www.youtube.com/watch?v=LvqfuvBPFTs …Jeff Goldblum om Oasis https://www.instagram.com/reel/C_LEfIIsmge/?igsh=OHh1cWl2ZTMxeDEz …Mofeta & Jerre https://sv.wikipedia.org/wiki/Mofeta_%26_Jerre …Sven Eriksson https://www.expressen.se/sport/fotboll/95-arige-pappan-om-sorgen-det-kommer-bli-tomt/ …Janne Anderssons Nigeriabrev https://www.dn.se/sport/janne-andersson-aktuell-for-nytt-jobb-under-tv-inspelning-pa-atlanten/ https://www.aftonbladet.se/sportbladet/fotboll/a/mPM57p/janne-andersson-blir-inte-ny-forbundskapten-for-landslaget-i-nigeria …Över Atlanten https://www.instagram.com/p/C--2VDZtlko/?hl=en&img_index=1 …astronauterna https://www.svt.se/nyheter/utrikes/astronauterna-fast-i-rymden-tvingas-lifta-med-spacex https://economictimes.indiatimes.com/magazines/panache/will-sunita-williams-soon-run-out-of-food-oxygen-at-space-station-nasa-clarifies/articleshow/112735023.cms?from=mdr …NMR-snubben https://www.aftonbladet.se/nyheter/a/vgkwBp/ki-forskare-fornekar-forintelsen-i-nmr-chatt …Talibanernas nya lagar https://www.dn.se/varlden/talibanerna-forbjuder-kvinnlig-sang-och-bilder-pa-levande-ting/ …Rymdstyrelsens logga https://www.rymdstyrelsen.se/contentassets/52b1d62defb04917a4de3859ed021113/rymdstyrelsen_ingang.jpg?width=454&rmode=crop&height=303&quality=80 Låtarna som spelades var: BAYRAKTAR is Life - Taras Borovko Hey Jude - The Beatles Werewolves of London - Warren Zevon Alla låtar finns i AMK Morgons spellista här: https://open.spotify.com/user/amk.morgon/playlist/6V9bgWnHJMh9c4iVHncF9j?si=so0WKn7sSpyufjg3olHYmg Stötta oss gärna på Swish, varje litet bidrag uppskattas enormt! 123 646 2006

Medverkande i detta avsnitt är Martin och Patrik. Gillar ni det vi producerar får ni gärna skicka in ett bidrag till bankkonto SEB 5708 35 378 011)     Intro, tecknat klipp för barn från 1993 som varnade för innehållet i fabriksframställd mat. https://www.youtube.com/watch?v=sjBxu9tqzZ0&t=1s2)     Martin och Patrik reflekterar kring den senaste tidens händelser, vi har bland annat gjort ett återbesök på Onsala Rymdobservatorium, besökt ett föredrag med läkaruppropets Sture Blomberg. Vidare samtalar vi kring det så kallade mordförsöket på Trump, farligheten med växtoljor, forntida avancerade civilisationer, den nya förintelselagstiftningen och terrorklassningen av förgrundsfigurer inom NMR etc.3)     Outro Dia Psalma med låten Tro rätt tro fel https://www.youtube.com/watch?v=gNFxj15qyoU4)     Ljudinspelning från föredraget med Sture Blomberg som hölls i närheten av Mölnlycke den 22:a maj 2024

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USA terrorklassar NMR. Kina kritiseras på G7:s toppmöte. Haverikommissionen riktar hård kritik mot Gröna Lund. Statyer som försvinner. Fotbolls-EM invigt i Tyskland. Vårdstrejken. Med mera. Lyssna på alla avsnitt i Sveriges Radio Play.

Nyheter och fördjupning från Sverige och världen. Lyssna på alla avsnitt i Sveriges Radio Play.

In this episode of the Go Hard Chick podcast, Dr. William Davis, M.D., a cardiologist and New York Times bestselling author, shares his journey from conventional interventional cardiology to a more holistic approach to heart health.  Dr. Davis shared his personal journey, which was significantly influenced by the sudden cardiac death of his mother shortly after a successful coronary procedure. This event led him to explore and eventually advocate for preventive measures outside the conventional medical practices. Dr. Davis introduces us to the concept of the Milwaukee Heart Scan, a diagnostic tool that measures the amount of plaque in arteries and predicts potential heart attacks years before they might occur. He emphasizes the limitations of traditional treatments like statins and low-fat diets, which he argued do not effectively stop the progression of heart disease. Instead, Dr. Davis advocates for a more comprehensive approach that includes dietary changes, identifying and managing the real causes of heart disease through advanced testing like NMR lipoprotein testing, and addressing vitamin D deficiencies. A significant part of our discussion also revolved around the coronary calcium score, a test that Dr. Davis feels is underutilized in medical practice due to its low cost and lack of profitability for hospitals. He explained how this test could provide crucial early warnings for heart disease risk. Dr. Davis also touched on broader health issues, including the detrimental effects of modern wheat consumption, the importance of gut health, and the potential dangers of popular diabetes medications like Ozempic and Wegovy. He explained how these drugs could lead to muscle loss and subsequent weight gain post-treatment, worsening patients' overall health. This episode is packed with critical insights on preventive health care, the importance of dietary choices, and the need for a shift in how we manage and understand chronic diseases. Dr. Davis's expertise and innovative approaches to cardiology and overall health provided our listeners with valuable information to consider and potentially implement in their health routines. Learn More About Dr. Davis: ​Website:  https://drdavisinfinitehealth.com/ Latest Book: Super Gut Join the Go Hard Chick email list!:  https://mailchi.mp/e071daa1445b/g68zgxope4 Connect with me: Website: www.gohardchick.com Instagram: @gohardchick and @krisalisefit Facebook:  Kristal Holmes Music Credit Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/kidcut/jazz-and-hop License code: MBVBUMAM7ITD58CK Music from Uppbeat (free for Creators!): Whoosh - swift cut Jam FX Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Kristal Holmes disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician or therapist. --- Send in a voice message: https://podcasters.spotify.com/pod/show/gohardchick/message

The global health landscape faces unprecedented challenges, with diseases proliferating despite advances in medical knowledge and technology. Despite significant investment in research across multiple disciplines, including physics, chemistry, biology, and engineering, some diseases remain elusive to diagnosis and treatment. In contrast, pre-colonial India boasted a healthy populace with a robust understanding of health and effective indigenous medical systems like Ayurveda. However, the dominance of Western medicine during colonization marginalized these traditional practices. Now, there's a resurgence of interest worldwide, including in India, in alternative approaches like Ayurveda, signaling a shift away from solely chemical-based treatments. The systems approach of the Tridosha model of Ayurveda holds a lot of relevant and intriguing aspects that have been found to be effective in diagnosing and treating various physiological conditions. Having said that, in today's world, with the recent Patanjali lawsuit, it is important to delineate what is truly scientific within Ayurveda as well as protect this age-old tradition from those who want to destabilize it, due to ideological reasons. To discuss all this and more, we have with us one of Bharat's most illustrious practitioners and scholars of Ayurveda - Dr. Rama Jayasundar. Dr. Jayasundar heads the Department of NMR, AIIMS, New Delhi. She has had a rather fascinating trajectory, having received her doctorate in Physics from Cambridge University with training in Nuclear Magnetic Resonance. While pioneering biomedical NMR work in Bharat, she went for a medical degree in Ayurveda (BAMS – Bachelor of Ayurvedic Medicine and Surgery), and today is the only one at both the national and international levels to hold dual degrees in Physics and Ayurveda. Her current research interests harness the distinctive facets of her expertise (NMR, Physics, Ayurveda and Allopathy) to shed light on the scientific basis and working of Ayurveda. Snakes in the Ganga - http://www.snakesintheganga.com Varna Jati Caste - http://www.varnajaticaste.com The Battle For IIT's - http://www.battleforiits.com Power of future Machines - http://www.poweroffuturemachines.com 10 heads of Ravana - http://www.tenheadsofravana.com To support Infinity Foundation's projects including the continuation of such episodes and the research we do: इनफिनिटी फ़ौंडेशन की परियोजनाओं को अनुदान देने के लिए व इस प्रकार के एपिसोड और हमारे द्वारा किये जाने वाले शोध को जारी रखने के लिए: http://infinityfoundation.com/donate-2/ --- Support this podcast: https://podcasters.spotify.com/pod/show/rajivmalhotrapodcast/support

BUFFALO, NY- May 7, 2024 – A new #research paper was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, “Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients.” Research into aging has grown substantially with the creation of molecular biomarkers of biological age that can be used to determine age acceleration. Concurrently, nuclear magnetic resonance (NMR) assessment of biomarkers of inflammation and metabolism provides researchers with new ways to examine intermediate risk factors for chronic disease. In this new study, researchers Henry Raab, Elizabeth R. Hauser, Lydia Coulter Kwee, Svati H. Shah, William E. Kraus, and Cavin K. Ward-Caviness from the U.S. Environmental Protection Agency and Duke University used data from a cardiac catheterization cohort to examine associations between biomarkers of cardiometabolic health and accelerated aging assessed using both gene expression (Transcriptomic Age) and DNA methylation (Hannum Age, GrimAge, Horvath Age, and Phenotypic Age). “This study utilizes the CATHGEN cohort from the Jiang et al. study to investigate associations between multiple epigenetic and transcriptomic aging biomarkers and a broad array of NMR-based measures of inflammation, lipid homeostasis, and diabetes risk.” Linear regression models were used to associate accelerated aging with each outcome (cardiometabolic health biomarkers) while adjusting for chronological age, sex, race, and neighborhood socioeconomic status. Their study shows a robust association between GlycA and GrimAge (5.71, 95% CI = 4.36, 7.05, P = 7.94 × 10−16), Hannum Age (1.81, 95% CI = 0.65, 2.98, P = 2.30 × 10−3), and Phenotypic Age (2.88, 95% CI = 1.91, 3.87, P = 1.21 × 10−8). The researchers also saw inverse associations between apolipoprotein A-1 and aging biomarkers. “These associations provide insight into the relationship between aging and cardiometabolic health that may be informative for vulnerable populations.” DOI - https://doi.org/10.18632/aging.205758 Corresponding authors - Cavin K. Ward-Caviness - ward-caviness.cavin@epa.gov Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.205758 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, biological aging, NMR, biomarkers, cardiac catheterization About Aging-US Aging publishes research papers in all fields of aging research including but not limited, aging from yeast to mammals, cellular senescence, age-related diseases such as cancer and Alzheimer's diseases and their prevention and treatment, anti-aging strategies and drug development and especially the role of signal transduction pathways such as mTOR in aging and potential approaches to modulate these signaling pathways to extend lifespan. The journal aims to promote treatment of age-related diseases by slowing down aging, validation of anti-aging drugs by treating age-related diseases, prevention of cancer by inhibiting aging. Cancer and COVID-19 are age-related diseases. Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM

Johne's Webinar Please note: The information provided during this podcast has been prepared for general informational purposes only and does not constitute advice. The information must not be relied upon for any purpose and no representation or warranty is given as to its accuracy, completeness or otherwise. Any reference to other organisations, businesses or products during the podcast are not endorsements or recommendations of Dairy Consulting Ltd or its affiliated companies. The views of the presenter are personal and may not be the views of Dairy Consulting Ltd. The contents of this podcast are the copyright of Dairy Consulting Ltd.

Whoa baby!  This was A LOT of fun.  Chris and Christian put together another spectacular production...the Ice Bath Challenge!  We are always talking about the benefits of a cold plunge so we decided it was time to share our experience with the NMR Board and a few other nutty members!  The gang does some warm up exercises, goes for a quick mile run, and then they prepare themselves for the chill!  We heard it all...laughing, crying, moaning, and screams of terror.  Join us for one of the most entertaining play by plays you'll ever hear.  We love you NMR!  Can't wait to do this again.  If you're interested in purchasing your own Nurecover Cold Plunge, feel free to use the code CHRISTIAN62079 for a discount.  We'll see you next time!  Until then, don't forget to get out there and...run as you are baby!

Chris and Christian meet up to give you a quick recap of the 2024 NYC Half Marathon!  It was an incredible day!  Beautiful weather and PRs for NMR!  Listen to us yammer on about how much fun we had and stick around to hear us go off the rails as usual!  We hope you enjoy the latest episode of Run As You Are...a conversation with people of all paces!

This lecture was given on October 11th, 2023, at Harvard University. For more information on upcoming events, visit us at thomisticinstitute.org/upcoming-events About the Speaker: Stephen Meredith is a professor at the University of Chicago's Departments of Pathology, Biochemistry and Molecular Biology, and Neurology. He is also an associate faculty member in the University of Chicago Divinity School. He has published more than 100 journal articles, focusing on the biophysics of protein structure. Much of his work has been the application of solution and solid-state NMR to the study of amyloid proteins associated with neurodegenerative diseases such as Alzheimer's Disease. He has also published articles on literature and philosophy in diverse aspects of medical humanities and bioethics. His teaching includes courses to graduate students in biochemistry and biophysics, medical students, and undergraduates and graduate students in the humanities, including courses on James Joyce's Ulysses, St. Thomas Aquinas, Augustine, Dostoevsky (focusing on Brothers Karamazov), Thomas Mann and David Foster Wallace. He is currently working on a book examining disease and the theological problem of evil. Other current writing projects include a study of James Joyce and the problem of evil.

Road Map to LongevityPodcast #1 – Longevity: exploring its definition and an approach to extending your vital, meaningful life.What gets measured gets done so the point of this podcast is for you to have tools for measuring your “rate of aging”. Using a simple questionnaire, some fitness measure and some lab measures you can gain keen insights to your rate of aging and more importantly engage steps to slow it down. Future webinars will explore exact action to engage and why these actions send youthful signals to your cells. First . . . measure it. We spoke of the Stevens study looking at numbers from the National Health and Nutrition Examination which showed that only 12% of Americans even qualify as being metabolically healthy. That is a sad fact but also a statistic that you easily avoid with proper lifestyle change. Beyond this we discussed the 2018 study in JAMA that compared 11 prosperous countries with good health care systems and showed that even though Americans smoke and drink less alcohol than many other countries, we ranked dead last in longevity!! Ouch! But wait . . . it gets worse. In 2023 the Centers for Disease Control in the U.S. reported that life expectancy had continued to DECLINE and our average life expectancy was now down to 76.4 years while Japan and other European countries continued to show gains in longevity. I have developed our own “Aging Score” based on an even deeper and more exacting exploration into labs and other lifestyle habits that offer a broader scope and so a more meaningful measure of your rate of aging. This questionnaire and aging guide can be seen on HippEvo.com by looking in the LEARN section under ARTICLES. https://www.hippevo.com/articles/aging-scoreTaking Action:It all starts by getting a baseline measure to see where you are. Your body wants to heal and can definitely get younger but how do know where to start if you don't have a line in the sand. So make the decision that want to be in control of your health journey rather than a victim of it. Get some labs done – I recommend starting with a look at some detailed labs.If insurance will cover your labs then that's great but if not then don't get robbed – use discounted lab option through HippEvoShop.com where you can order labs on a cash pay basis and save a ton. You need an NMR lipid panel, HgbA1c, Glucose (chem14) and insulin, and a CRP-hs as a good start point. Add to this your sex appropriate hormone test panel that includes testosterone and SHBG.Yes, there is more that can be measured but this is a good start. If you want to order all of the labs seen in the “Aging Score” questionnaire then contact Liz at HippEvo.com (Phone 513-366-2100) and request the Longevity full panel which includes: NMR lipids, Insulin, Chem14, HgbA1c, Testosterone, DHEAS, Thyroid, CRP, ApoE gene, Omega 6:3 ratio, Lp(a), Glutathione, Vitamin D, SHBG. The price is $699.00 but there isn't a cheaper more inclusive panel to be found anywhere.Then measure your fitness as outlined on the “Aging Score” sheet. This is when reality sets in but that's a good thing. No more mystery. We are filling in facts and details to arrive at a statement of health. You are putting yourself in the driver seat by laying claim to your reality. More importantly, once measured you can begin to sculpt a different result. Don't be American – Age slowly.

After Chris' report this week, Will and Ben are joined by Richard Miller, Genomics Business Manager at NMR, Rose Jackson, Kite's Head of Genetics and dairy farmer Rhys Davies for a discussion about NMR's next-generation in milk recording, GenoCells. Richard explains how GenoCells works, using one bulk milk sample to provide individual cow Somatic Cell Counts (SCC) for the herd and how the technology allows you to detect and identify specific cows for targeted health interventions. Rose outlines the potential benefits to both farms and vets, including increased efficiency and improved cow health and welfare. Rhys explains where they are at in their use of GenoCells, how it compares to traditional milk recording and the practical application and advantages in his block calving herd.Please note: The information provided during this podcast has been prepared for general informational purposes only and does not constitute advice. The information must not be relied upon for any purpose and no representation or warranty is given as to its accuracy, completeness or otherwise. Any reference to other organisations, businesses or products during the podcast are not endorsements or recommendations of Dairy Consulting Ltd or its affiliated companies. The views of the presenter are personal and may not be the views of Dairy Consulting Ltd. The contents of this podcast are the copyright of Dairy Consulting Ltd.

It's another episode of your favorite podcast about running!  Chris and Christian celebrate the new year and catch up on all things NMR!  They talk ice baths, New Year's resolutions, upcoming events for NMR, and share the typical good vibes you'd expect from these two!  Take a listen!  Most importantly, don't forget to get out there and...run as you are baby!

Stephen Meredith is a professor at the University of Chicago's Departments of Pathology, Biochemistry and Molecular Biology, and Neurology. He is also an associate faculty member in the University of Chicago Divinity School. He has published more than 100 journal articles, focusing on the biophysics of protein structure. Much of his work has been the application of solution and solid-state NMR to the study of amyloid proteins associated with neurodegenerative diseases such as Alzheimer's Disease. He has also published articles on literature and philosophy in diverse aspects of medical humanities and bioethics. His teaching includes courses to graduate students in biochemistry and biophysics, medical students, and undergraduates and graduate students in the humanities, including courses on James Joyce's Ulysses, St. Thomas Aquinas, Augustine, Dostoevsky (focusing on Brothers Karamazov), Thomas Mann and David Foster Wallace. He is currently working on a book examining disease and the theological problem of evil. Other current writing projects include a study of James Joyce and the problem of evil.

Jux nos cuenta como fue su vida antes de su fama en Internet, su paso por el NMR crew y qué hizo después de su término, no se lo pierdan. Learn more about your ad choices. Visit megaphone.fm/adchoices

Don Westacott VE6HQ, believes that his early foundation in amateur radio contributed to his professional success through the multiple disciplines and out of the box thinking that is amateur radio.  After a successful career and an expert in subsurface measurements and remote sensing for the petroleum  industry, Don now likes to work 20 meters and refine his test equipment bench using the latest low cost solutions like the NanoVNA.  VE6HQ is my QSO Today.

Watch this NMR in video form on Patreon at any tier! John and Daryn get to the bottom of the age old question: is it correct to brush then floss or floss then brush!? It's John's first holidays with Magic. Sign up for Patreon here and watch the video version of this episode! And get bonus episodes of the show, exclusive blogs, videos, photos and direct access to John and Daryn! Starting at $5 a month, your contribution greatly supports our independent show! http://patreon.com/shakenanddisturbed Want Shaken and Disturbed merch? T-shirts, pillows, hoodies, phone cases, stickers and more are now available here: Shaken and Disturbed MERCH STORE Follow John on Twitter @jthrasher, Instagram @jthrasher and TikTok @johnthrasher Follow Daryn on Twitter @CarpeDaryn and Instagram @CarpeDaryn Join the official Shake and Disturbed Fans Facebook Group here! 

Cholesterol testing is among the most common blood tests run in conventional healthcare, yet it is a perennial source of confusion and, to be honest, abuse by doctors who don't appreciate the full implications of the values. It may surprise you to know that doctors focus on the least helpful values such as total or LDL cholesterol while often ignoring the two genuinely helpful values, HDL cholesterol and triglycerides. HDL for instance is packed with useful insights into your health, as it is a reliable index of metabolic health. Low HDL, that I would define as less than 60 mg/dl, is a reflection of multiple health distortions such as insulin resistance, inflammation, excessive intra-abdominal fat, small LDL particles and VLDL that cause heart disease. You might also be surprised to learn that consuming fats only spikes triglyceride levels for a few hours, whereas the process of your liver converting carbohydrates to triglycerides can cause a much larger increase after six to eight hours or more. Discover the factors that can amplify this process, including insulin resistance, inflammation, excessive intra-abdominal fat, and even dysbiosis and small intestine bacterial overgrowth. The road to cardiovascular health doesn't have to be paved with cholesterol. We'll reveal how VLDL particles and triglyceride levels are intricately linked, why it's essential to keep your triglycerides below 60 milligrams per deciliter, and how higher triglycerides can result in lower HDL levels. Discover how simple dietary changes can lead to lower triglycerides and higher HDL levels, and why measuring LDL particles using NMR lipoprotein analysis offers a more accurate picture than the commonly used LDL cholesterol. Join us as we dispel the myths around cholesterol and empower you to take control of your cardiovascular health.For BiotiQuest probiotics including Sugar Shift, go here.A 15% discount is available for Defiant Health podcast listeners by entering discount code UNDOC15 (case-sensitive) at checkout.*_________________________________________________________________________________Get your 15% Paleovalley discount on fermented grass-fed beef sticks, Bone Broth Collagen, low-carb snack bars and other high-quality organic foods here.* For 12% off every order of grass-fed and pasture-raised meats from Wild Pastures, go here.*Dr. Davis and his staff are financially compensated for promoting BiotiQuest and Paleovalley products.Support the showBooks: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed

Did you know that blood cholesterol levels are influenced by far more than just the foods we eat?Are you eager to know how to assess healthspan using your own body's data? This episode of Longevity by Design is an Ask Me Anything between Dr. Gil Blander and Ashley Reaver. We gathered frequently asked questions from the Longevity by Design audience and discussed topics fundamental to longevity. Ashley Reaver begins the conversation with a deep dive into cholesterol—including the relationship between dietary cholesterol and blood cholesterol, the two most impactful nutrients on our blood cholesterol levels, how to navigate a family history of high cholesterol, and much more. Dr. Blander then answers questions about health metrics, explaining why VO2max is one of the best markers to assess heart health. He also discusses other markers of healthspan, the value of quality sleep, and the latest science on NAD+ precursors, including NMR and NM. Timestamps: Introduction: (0:00–2:22) The relationship between dietary cholesterol and blood cholesterol: (2:22–3:34) Eggs and cholesterol: (3:34–3:50)Absorbing dietary cholesterol: (3:50–4:10)About 20% of dietary cholesterol influences blood cholesterol: (4:10–5:40)Why you should test your cholesterol every 3 months: (5:40–7:54) Which cholesterol markers you should test: (7:54–9:20) Holding yourself accountable to your health: (9:20–12:03) Navigating a family history of high cholesterol: (12:03–14:08)The two most important nutrients that impact blood cholesterol: (14:08–15:03) Focusing on the aspects of your health that you can control: (15:03–17:40) Saturated fat contributes to elevated cholesterol: (17:40–20:37) Soluble fiber helps lower ApoB: (20:37–23:30) Insoluble fiber: (22:30–25:00) Fiber supplements: (25:00–27:00) Common myths about cholesterol: (27:00–31:54) VO2max is the best physiomarker of cardiovascular health: (31:54–36:00)VO2max declines with age: (36:00–37:40) Sex differences in VO2max: (37:40–39:10)VO2max correlates with other physiomarkers of health: (39:10–42:00)VO2max is correlated with biomarkers of metabolic health: (42:00–46:10)How to improve VO2max: (46:10–48:40) Sleep and VO2max: (48:40–50:00)The importance of adequate sleep for healthspan: (50:00–51:50)Grip strength is correlated with longevity: (51:50–58:10) Using your body's data to assess your health: (58:10–1:04:30) Weight loss strategies and GLP-1 agonists: (1:04:30–1:08:06) Intermittent fasting: (1:08:06–1:09:30) Ashley Reaver's tips for weight maintenance: (1:09:30–1:15:10) NMN vs NR: which is the best NAD+ precursor: (1:15:10–1:18:17) The scientific rigor behind InsideTracker recommendations: (1:18:17–1:22:15) Top tip for healthspan: (1:22:15–end) Listen to all episodes of Longevity by Design at https://info.insidetracker.com/longevitybydesign 

References Cureus. 2022. 14(9): e29696.doi:10.7759/cureus.29696 NMR Biomed. 2021 Feb;34(2):e4448. NMR in Biomedicine. 2023.  e4896. ISSN 0952-3480 Nutrients. 2023 May; 15(9): 2029. Mozart, WA. 1791 K 626 Requiem in d minor. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Surprise! John and Daryn met up in NYC to record this week's NMR (as well as Sunday's full episode)! They recap their love for each other, John's small Diet Cokes, and the US Open among other things! Our new Shaken and Disturbed Patreon perks and tiers are live NOW! Help support our show for as little as $5 a month! We now have Sussy Radish stickers and video podcasts available at certain levels! Your support keeps the show running and the bills paid so that we can keep making and publishing new episodes! Sign up for Patreon here: http://patreon.com/shakenanddisturbed Want Shaken and Disturbed merch? T-shirts, pillows, hoodies, phone cases, stickers and more are now available here: Shaken and Disturbed MERCH STORE And if you've already signed up for Patreon, thank you, Mom and Dad love you.

Today, I am blessed to have Dr. Philip Ovadia. He is a board-certified Cardiac Surgeon and the founder of Ovadia Heart Health. From his personal experience, he made a goal to maintain his patients' metabolic health and keep them off the surgery table.  Despite being a surgeon, Dr Philip is overweight. Whatever effort he makes following the recommendation of the flawed medical system, he remains overweight. But with the help of his wife, Dr. Philip began to take action, search for the truth, and eventually reach his goal of being metabolically healthy.  Now, Dr. Philip made it his mission to help people fix their metabolic weight. With his knowledge and experience, he will do anything to awaken people from our current flawed medical system.  Dr. Philip is also the author of the book Stay off My Operating Table: A Heart Surgeon's Metabolic Health Guide to Lose Weight, Prevent Disease, and Feel Your Best Every Day.  In this episode, Dr. Philip Ovadia discusses how heart disease started and the factor that causes heart disease. He also talks about how stress can trigger heart disease. Furthermore, Dr. Philip shared his knowledge about why it is important to have lab tests, the truth about fish oil, and the diet we should have to achieve a metabolically healthy body. Tune in as we chat about heart disease, cholesterol, stress, lab test, fish oil, proper diet, and many more!  Get Dr Philip Ovadia's book Stay Off My Operating Table Here: https://www.amazon.com/Stay-off-Operating-Table-Metabolic-ebook/dp/B09GL4S6G4/benazadi-20 Download your FREE Vegetable Oil Allergy Card here: https://onlineoffer.lpages.co/vegetable-oil-allergy-card-download/ / / E P I S O D E   S P ON S O R S  Wild Pastures: $20 OFF per Box for Life + Free Shipping for Life + $15 OFF your 1st Box! https://wildpastures.com/promos/save-20-for-life-lf?oid=6&affid=132&source_id=podcast&sub1=ad BonCharge: Blue light Blocking Glasses, Red Light Therapy, Sauna Blankets & More. Visit https://boncharge.com/pages/ketokamp and use the coupon code KETOKAMP for 15% off your order.  Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. [01:05] Heart Disease: The History of How The Leading Killer Disease Worldwide Began  -       In the early 1900s, heart disease is an exceedingly rare condition. -       Eventually, it became more prominent, and in the 1950s, it reached a crisis point. -       70 years later, the solution to fight heart disease still has yet to progress. -       Cholesterol was not the problem.  [15:14] What Is the One Factor That Causes Heart Disease? Know Your Risk  -   Heart disease is not multifactorial. It just has one factor that contributes to heart disease. -   In atherosclerotic heart disease, damage to the blood vessel wall is a primary contributing component. -   These damages to the blood vessel are caused by common factors such as insulin resistance, smoking, and high blood pressure. -   Vegetable and seed oils are also a contributor to heart disease.  [24:49] What's the Connection Between Being Stressed and Heart Disease? What Should You Do?  -       Stress plays an important role in heart disease, and it's one of the pillars of health -       The difficult part about stress is we don't have a great way of measuring it. -       There's a cardiac condition called Takotsubo cardiomyopathy, a stress-induced heart attack. -       Managing stress is a very important aspect of mitigating your risk for heart disease.  [28:19] Lab Test: The Importance of Getting a Lab Assessment Into Our Bodies  -       The amount of cholesterol isn't the right thing to look at. We need to look at the quality of the cholesterol in our bodies. -       Until you get damage to the blood vessel and the cholesterol particles, you cannot produce heart disease and plaques in the heart's blood vessels. -       Push to get an NMR panel. It is not expensive and is usually covered by insurance. -       You need to know a doctor who knows what they're looking at. -       One test that is essential for people to get is called a coronary artery calcium scan.  That scan will show us whether or not you're accumulating damage to the blood vessels in your heart. -       High sensitivity C reactive protein test is another important scan patients should have.  [49:57] Have You Heard About Fish Oil? Should We Take It or Not?  -        The reason that fish oil gets recommended is because it's thought to be anti-inflammatory. -       Dr. Philip advocates for people to figure out what's causing the inflammation and eliminate the inflammation. And then we don't need anti-inflammatories like fish oil anymore. -       if you aren't oxidizing things in the first place and if you aren't first inducing inflammation. Anti-inflammatory drugs and antioxidants are not necessary. -       Get on a low-inflammatory lifestyle and diet; you don't need the anti-inflammatory benefits. [54:22]   You are What You Eat: What Diet Should You Have to Be Metabolically Healthy?  -   Eat whole real food. Since the introduction of processed food, our health has worsened. -   Balance your diet between eating whole real animal proteins and whole real vegetables, plants, and fruits. -   Different diet strategies each have their benefits and drawbacks. -   If you feel metabolically healthy in your chosen diet, continue it. If not, changes are needed to be made. AND MUCH MORE! Resources from this episode: ●  Dr. Philip Ovadia's Website: https://ovadiahearthealth.com/ ●  I Fix Hearts Website: https://ifixhearts.com/ ●  Follow Dr. Philip Ovadia ●  Instagram: https://www.instagram.com/ovadia_heart_health/?hl=en  ●  Twitter: https://twitter.com/ifixhearts?s=20 ●  YouTube: https://www.youtube.com/@IFixHearts/videos ●  LinkedIn: https://www.linkedin.com/in/philip-ovadia-heart-health/ ●  Get Dr Philip Ovadia's book Stay Off My Operating Table Here: https://www.amazon.com/Stay-off-Operating-Table-Metabolic-ebook/dp/B09GL4S6G4/benazadi-20 ●  Join the Keto Kamp Academy: https://ketokampacademy.com/7-day-trial-a ●  Watch Keto Kamp on YouTube: https://www.youtube.com/channel/UCUh_MOM621MvpW_HLtfkLyQ Download your FREE Vegetable Oil Allergy Card here: https://onlineoffer.lpages.co/vegetable-oil-allergy-card-download/ / / E P I S O D E   S P ON S O R S  Wild Pastures: $20 OFF per Box for Life + Free Shipping for Life + $15 OFF your 1st Box! https://wildpastures.com/promos/save-20-for-life-lf?oid=6&affid=132&source_id=podcast&sub1=ad BonCharge: Blue light Blocking Glasses, Red Light Therapy, Sauna Blankets & More. Visit https://boncharge.com/pages/ketokamp and use the coupon code KETOKAMP for 15% off your order.  Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. // F O L L O W ▸ instagram | @thebenazadi | http://bit.ly/2B1NXKW ▸ facebook | /thebenazadi | http://bit.ly/2BVvvW6 ▸ twitter | @thebenazadi http://bit.ly/2USE0so ▸ tiktok | @thebenazadi https://www.tiktok.com/@thebenazadi Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Ben Azadi disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility of statements made by guests. This podcast does not make any representations or warranties about guests qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.

In January 2023, Ronn Richard announced his plans to retire from his role as president and CEO of the Cleveland Foundation after 20 years at the helm of the world's first community foundation. As Mr. Richard prepares to retire at the end of July, he will join Tony Richardson, President of The George Gund Foundation, in a conversation reflecting on his tenure at the Cleveland Foundation and his hopes for the future of Greater Cleveland.rnrnMr. Richard came to Cleveland to lead the foundation in 2003, following a career that spanned the public, private and nonprofit sectors. During his time at the foundation, Mr. Richard doubled the organization's endowment and grew its annual grantmaking to record levels while overseeing transformative investments in public education, neighborhood development, arts and culture, advanced energy, leadership development, research and innovation, and more.rnrnIn this forum, Mr. Richard will share insights and lessons from his tenure at the Cleveland Foundation as well as his perspective on the role of community philanthropy in moving Greater Cleveland forward.

This lecture was given on March 8th, 2023 at Vanderbilt University. For more information on upcoming events, please visit our website: thomisticinstitute.org/upcoming-events Speaker Bio: Stephen Meredith is a professor at the University of Chicago's Departments of Pathology, Biochemistry and Molecular Biology, and Neurology. He is also an associate faculty member in the University of Chicago Divinity School. He has published more than 100 journal articles, focusing on the biophysics of protein structure. Much of his work has been the application of solution and solid-state NMR to the study of amyloid proteins associated with neurodegenerative diseases such as Alzheimer's Disease. He has also published articles on literature and philosophy in diverse aspects of medical humanities and bioethics. His teaching includes courses to graduate students in biochemistry and biophysics, medical students, and undergraduates and graduate students in the humanities, including courses on James Joyce's Ulysses, St. Thomas Aquinas, Augustine, Dostoevsky (focusing on Brothers Karamazov), Thomas Mann and David Foster Wallace. He is currently working on a book examining disease and the theological problem of evil. Other current writing projects include a study of James Joyce and the problem of evil.

Chris and Christian take an Inferno Hot Pilates class with the one and only, Lori Innamorata!  After class they crush some coconut water and get down to business!  Lori is our local energizer bunny!  She likes it sweaty all the time.  Two a days?  Try three a days!  Her smile and personality are absolutely contagious (just ask Tim)!  She's known as our local NMR pirate...traveling all over the world upon her ship at sea!  Join us for a very special interview with the one and only, Lori Innamorata!

Chris and Christian sit down with the coolest sisters-in-law in town!  Amy and Lauren Friel!  Two OG members of NMR that bring nothing but positive, competitiveness, style, and sweetness to every run!  One is from down south and the other is currently living in China!  Join us as we discuss all things running local and running in China!  We hope you enjoy our first international podcast with Amy and Lauren Friel!

Whoa!  It's been a minute since you've heard from us!  Chris and Christian apologize for their disappearance and discuss a few NMR related updates!  We just wanted to sign on and remind you all that we still love this podcast and still love running!  We will be back soon with plenty of exciting guests and fun filled episodes this Summer!  As always, "Don't forget to get out there and run as you are baby!"

This lecture was given on March 8, 2023 at Vanderbilt University. The handout for this lecture can be found here: https://tinyurl.com/yw4y92cn. For more information on upcoming events, please visit our website at www.thomisticinstitute.org. About the speaker: Stephen Meredith is a professor at the University of Chicago's Departments of Pathology, Biochemistry and Molecular Biology, and Neurology. He is also an associate faculty member in the University of Chicago Divinity School. He has published more than 100 journal articles, focusing on the biophysics of protein structure. Much of his work has been the application of solution and solid-state NMR to the study of amyloid proteins associated with neurodegenerative diseases such as Alzheimer's Disease. He has also published articles on literature and philosophy in diverse aspects of medical humanities and bioethics. His teaching includes courses to graduate students in biochemistry and biophysics, medical students, and undergraduates and graduate students in the humanities, including courses on James Joyce's Ulysses, St. Thomas Aquinas, Augustine, Dostoevsky (focusing on Brothers Karamazov), Thomas Mann and David Foster Wallace. He is currently working on a book examining disease and the theological problem of evil. Other current writing projects include a study of James Joyce and the problem of evil.

The speaker's handout may be found here: https://tinyurl.com/mry498c9 This lecture was given on February 15, 2023, at the University of Nebraska-Lincoln. For more information on upcoming events, please visit our website at thomisticinstitute.org. About the speaker: Stephen Meredith is a professor at the University of Chicago's Departments of Pathology, Biochemistry and Molecular Biology, and Neurology. He is also an associate faculty member in the University of Chicago Divinity School. He has published more than 100 journal articles, focusing on the biophysics of protein structure. Much of his work has been the application of solution and solid-state NMR to the study of amyloid proteins associated with neurodegenerative diseases such as Alzheimer's Disease. He has also published articles on literature and philosophy in diverse aspects of medical humanities and bioethics. His teaching includes courses to graduate students in biochemistry and biophysics, medical students, and undergraduates and graduate students in the humanities, including courses on James Joyce's Ulysses, St. Thomas Aquinas, Augustine, Dostoevsky (focusing on Brothers Karamazov), Thomas Mann and David Foster Wallace. He is currently working on a book examining disease and the theological problem of evil. Other current writing projects include a study of James Joyce and the problem of evil.

We're finally back with a new NMR this week! John thinks Hanson is in the World Cup, and Daryn has a special Christmas gift for John that they've talked about on the show at some point in the year. Do you think you can guess what it is? Want Shaken and Disturbed merch? T-shirts, pillows, hoodies, phone cases, stickers and more are now available here: Shaken and Disturbed MERCH STORE Support the show directly by signing up for our Patreon. Bonus episodes, exclusive announcements, exclusive behind-the-scenes photos and videos, and even a chance to co-host with us all available at various tiers! Sign up for Patreon here: http://patreon.com/shakenanddisturbed And if you've already signed up for Patreon, thank you, Mom and Dad love you.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Gerald Shulman is a Professor of Medicine, Cellular & Molecular Physiology, and the Director of the Diabetes Research Center at Yale. His pioneering work on the use of advanced technologies to analyze metabolic flux within cells has greatly contributed to the understanding of insulin resistance and type 2 diabetes. In this episode, Gerald clarifies what insulin resistance means as it relates to the muscle and the liver, and the evolutionary reason for its existence. He goes into depth on mechanisms that lead to and resolve insulin resistance, like the role of diet, exercise, and pharmacological agents. As a bonus, Gerald concludes with insights into Metformin's mechanism of action and its suitability as a longevity agent. We discuss: Gerald's background and interest in metabolism and insulin resistance (2:30); Insulin resistance as a root cause of chronic disease (6:30); How Gerald uses NMR to see inside cells (10:00); Defining and diagnosing insulin resistance and type 2 diabetes (17:15); The role of lipids in insulin resistance (29:15); Confirmation of glucose transport as the root problem in lipid-induced insulin resistance (38:15); The role of exercise in protecting against insulin resistance and fatty liver (48:00); Insulin resistance in the liver (1:05:00); The evolutionary explanation for insulin resistance—an important tool for surviving starvation (1:15:15); The critical role of gluconeogenesis, and how it's regulated by insulin (1:20:30); Inflammation and body fat as contributing factors to insulin resistance (1:30:15); Treatment approaches for fatty liver and insulin resistance, and an exciting new pharmacological approach (1:39:15); Metformin's mechanism of action and its suitability as a longevity agent (1:56:15); and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube