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Benzodiazepine use in relation to long-term dementia risk and imaging markers of neurodegeneration: a population-based study
Trial of the Week: ESETT Special Guest: Ashley McCormick, PharmD, BCPS, BCCCP Ashley McCormick joins to discuss the April Trial of the Week “Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus” the ESETT study, published in NEJM in 2019. We set the scene by reviewing ASM PK/PD properties and discussing if there was a standard of care first-line treatment. Then we do a deep dive into the ESETT trial of the week. Did the 75kg dose cap influence results? How appropriate was the BZD dosing? How does this % of seizure cessation compare to other studies? Where did this dosing scheme come from? Trial fun facts, medication safety considerations, and much, much more. Reference list: https://pharmacytodose.files.wordpress.com/2024/04/esett-trial-of-the-week-references.pdf PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices
最近爆發的幼兒園疑似驗出巴比妥以及BZD案件在社會中持續發酵,家長們更是人心惶惶...最後一回的特輯我們找來真正專業的藥物濫用專家山姆(對, 本頻道的公衛博士山姆的強項就是藥物濫用想不到吧!)用最深入淺出的解說,讓大家可以從不同面向對這個案件有更清楚的了解。 [凱莉陪你上下班] 是Yo! What's Up在幹嘛的短篇通勤單元, 內容多元包含了壓力管理、時間管理、收納專家建議、深入淺出行為學、以及一些日常有趣的新聞, 用滿滿的心意陪伴聽眾的通勤以及空閒時間! 想到的時候, 請讓我的聲音陪你走一段吧。 --- 喜歡我們頻道無痛學習知識的主軸? 點擊這個連結 用一杯焦糖瑪奇朵的錢支持我們繼續做出與眾不同的知識企劃! 想針對本集節目內容做進一步討論或是跟我們聯絡?快寫信 給我們 yowhatsup.podcast@gmail.com到Apple podcast下面給我們留評論跟我們互動在Firstory的單集專屬留言區留言來Yo! What's Up 在幹嘛的IG 或是臉書 找我們或是加入我們的臉書秘密VIP好好生活小圈圈 一起在忙亂生活中找到秩序好好過生活我們等你!!! -- 頭尾配樂版權宣告: 浪漫民謠配樂 編曲: Music Time 版權音樂團隊 作曲: Music Time 版權音樂團隊 製作: Music Time 專業配樂音效後製 發行: 更多優質播客音樂/後製服務>> https://reurl.cc/AgE6Lp 授權: https://creativecommons.org/licenses/by-nd/4.0/deed.zh_TW 連結: 原創音樂人需要你的贊助>> https://reurl.cc/MZY6OL Powered by Firstory Hosting
最近爆發的幼兒園疑似驗出巴比妥以及BZD案件在社會中持續發酵,家長們更是人心惶惶...本頻道找來專業的專家用最深入淺出的解說,讓大家可以從不同面向對這個案件有更清楚的了解。第三回邀請到的是曾經執行毒品檢驗的分析化學家2號娃娃魚,我們將在節目中跟大家從所謂的藥物指紋辨識聊起。 [凱莉陪你上下班] 是Yo! What's Up在幹嘛的短篇通勤單元, 內容多元包含了壓力管理、時間管理、收納專家建議、深入淺出行為學、以及一些日常有趣的新聞, 用滿滿的心意陪伴聽眾的通勤以及空閒時間! 想到的時候, 請讓我的聲音陪你走一段吧。 --- 喜歡我們頻道無痛學習知識的主軸? 點擊這個連結 用一杯焦糖瑪奇朵的錢支持我們繼續做出與眾不同的知識企劃! 想針對本集節目內容做進一步討論或是跟我們聯絡?快寫信 給我們 yowhatsup.podcast@gmail.com到Apple podcast下面給我們留評論跟我們互動在Firstory的單集專屬留言區留言來Yo! What's Up 在幹嘛的IG 或是臉書 找我們或是加入我們的臉書秘密VIP好好生活小圈圈 一起在忙亂生活中找到秩序好好過生活我們等你!!! -- 頭尾配樂版權宣告: 浪漫民謠配樂 編曲: Music Time 版權音樂團隊 作曲: Music Time 版權音樂團隊 製作: Music Time 專業配樂音效後製 發行: 更多優質播客音樂/後製服務>> https://reurl.cc/AgE6Lp 授權: https://creativecommons.org/licenses/by-nd/4.0/deed.zh_TW 連結: 原創音樂人需要你的贊助>> https://reurl.cc/MZY6OL Powered by Firstory Hosting
最近爆發的幼兒園疑似驗出巴比妥以及BZD案件在社會中持續發酵,家長們更是人心惶惶...本頻道找來專業的專家用最深入淺出的解說,讓大家可以從不同面向對這個案件有更清楚的了解。第二回邀請到的是駐站過期藥師以及分析化學家佩勛,他們將在節目中跟大家從所謂的零檢出開始聊。 [凱莉陪你上下班] 是Yo! What's Up在幹嘛的短篇通勤單元, 內容多元包含了壓力管理、時間管理、收納專家建議、深入淺出行為學、以及一些日常有趣的新聞, 用滿滿的心意陪伴聽眾的通勤以及空閒時間! 想到的時候, 請讓我的聲音陪你走一段吧。 --- 喜歡我們頻道無痛學習知識的主軸? 點擊這個連結 用一杯焦糖瑪奇朵的錢支持我們繼續做出與眾不同的知識企劃! 想針對本集節目內容做進一步討論或是跟我們聯絡?快寫信 給我們 yowhatsup.podcast@gmail.com到Apple podcast下面給我們留評論跟我們互動在Firstory的單集專屬留言區留言 https://open.firstory.me/user/ck9uvd973ol2m08737mujij4z/comments來Yo! What's Up 在幹嘛的IG 或是臉書 找我們或是加入我們的臉書秘密VIP好好生活小圈圈 一起在忙亂生活中找到秩序好好過生活我們等你!!! -- 頭尾配樂版權宣告: 浪漫民謠配樂 編曲: Music Time 版權音樂團隊 作曲: Music Time 版權音樂團隊 製作: Music Time 專業配樂音效後製 發行: 更多優質播客音樂/後製服務>> https://reurl.cc/AgE6Lp 授權: https://creativecommons.org/licenses/by-nd/4.0/deed.zh_TW 連結: 原創音樂人需要你的贊助>> https://reurl.cc/MZY6OL Powered by Firstory Hosting
最近爆發的幼兒園疑似驗出巴比妥以及BZD案件在社會中持續發酵,家長們更是人心惶惶...本頻道找來專業的專家用最深入淺出的解說,讓大家可以從不同面向對這個案件有更清楚的了解。第一回邀請到的是分析化學質譜學家佩勛,他將在節目中跟號稱捷運東門站宋慧喬的凱莉一起從巴比妥的檢驗方法開始聊。 [凱莉陪你上下班] 是Yo! What's Up在幹嘛的短篇通勤單元, 內容多元包含了壓力管理、時間管理、收納專家建議、深入淺出行為學、以及一些日常有趣的新聞, 用滿滿的心意陪伴聽眾的通勤以及空閒時間! 想到的時候, 請讓我的聲音陪你走一段吧。 --- 喜歡我們頻道無痛學習知識的主軸? 點擊這個連結 用一杯焦糖瑪奇朵的錢支持我們繼續做出與眾不同的知識企劃! 想針對本集節目內容做進一步討論或是跟我們聯絡?快寫信 給我們 yowhatsup.podcast@gmail.com到Apple podcast下面給我們留評論跟我們互動在Firstory的單集專屬留言區留言來Yo! What's Up 在幹嘛的IG 或是臉書 找我們或是加入我們的臉書秘密VIP好好生活小圈圈 一起在忙亂生活中找到秩序好好過生活我們等你!!! -- 頭尾配樂版權宣告: 浪漫民謠配樂 編曲: Music Time 版權音樂團隊 作曲: Music Time 版權音樂團隊 製作: Music Time 專業配樂音效後製 發行: 更多優質播客音樂/後製服務>> https://reurl.cc/AgE6Lp 授權: https://creativecommons.org/licenses/by-nd/4.0/deed.zh_TW 連結: 原創音樂人需要你的贊助>> https://reurl.cc/MZY6OL Powered by Firstory Hosting
本節新聞重點: ▲新北市幼兒園幼童 部北免費檢驗巴比妥.BZD ▲習近平會見「中國老朋友」 高規格接待比爾蓋茲 ▲中國球迷亂入場抱梅西 諷保全只顧看球 ▲玻利維亞急凍至冰點 墨西哥「熱爆」成另個世界 |更多新聞| ◎台視新聞訂閱→https://www.youtube.com/c/ttvnewsview ◎台視直播訂閱→https://www.youtube.com/c/twlivenews ◎台視臉書粉絲團訂閱→https://www.facebook.com/ttvnews/ ◎台視新聞IG訂閱→https://www.instagram.com/ttvnews_tw/
Share this post with others: The Z-drugs: Ambien. Lunesta. Sonata. What are these? Are they benzos? Hypnotics? When did they hit the market? Can they cause dependence? Withdrawal? BIND? These questions and more will be the focus of our feature today. In today's episode, we focus on nonbenzodiazepines or Z-drugs. How are they like benzodiazepines, and how are they different? We also answer some questions about dosage, duration, and rebounding and we hear a story of struggle from Tulsa, Oklahoma. Podcast ID: BFP111 Chapters 00:00 INTRODUCTION02:09 My Podcast Voice05:33 Progress on Website06:33 Peer Support Training Update09:10 Struggles, Symptoms, and the Podcast14:47 A reason why, or just coincidence?18:16 MAILBAG18:58 Does dosage or duration matter?21:24 Rebound from medical procedures?24:31 BENZO STORY32:28 FEATURE: Z-drugs34:38 What are Z-drugs?36:00 When did Z-drugs hit the market?36:36 Do Z-drugs act like BZDs on the body?37:54 Z-drugs often partnered with BZDs39:46 What are Z-drugs prescribed for?40:07 The Quest for the Magic Pill42:04 Are Z-drugs less likely to cause symptoms?45:06 What are the Z-drug side effects?47:02 Are Z-drug symptoms different?48:20 How to taper from Z-drugs?49:05 BZD and Z-drug Terminology51:48 MOMENT OF PEACE Resources The following resource links are provided as a courtesy to our listeners. They do not constitute an endorsement by Benzo Free of the resource or any recommendations or advice provided therein. Ashton, C. Heather. Benzodiazepines: How They Work and How to Withdraw (aka The Ashton Manual). 2002. Accessed April 13, 2016. http://www.benzo.org.uk/manual. Brandt J, Leong C. Benzodiazepines and Z-Drugs: An Updated Review of Major Adverse Outcomes Reported on in Epidemiologic Research. Drugs R D. 2017 Dec;17(4):493-507. doi: 10.1007/s40268-017-0207-7. PMID: 28865038; PMCID: PMC5694420. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694420/. Foster, D E. Benzo Free: The World of Anti-Anxiety Drugs and the Reality of Withdrawal. Erie, CO: Denim Mountain Press, 2018. https://www.benzofree.org/book. Kay, Abigail L. et al. Drug Abuse, Dependency, and Withdrawal. Therapy in Sleep Medicine. 2012. https://doi.org/10.1016/C2009-0-40426-4. Schifano F, Chiappini S, Corkery JM, Guirguis A. An Insight into Z-Drug Abuse and Dependence: An Examination of Reports to the European Medicines Agency Database of Suspected Adverse Drug Reactions. Int J Neuropsychopharmacol. 2019 Apr 1;22(4):270-277. doi: 10.1093/ijnp/pyz007. PMID: 30722037; PMCID: PMC6441128. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441128/. U.S. Food & Drug Administration. Taking Z-drugs for Insomnia? Know the Risks. Last Updated April 30, 2019. Accessed November 30, 2022. https://www.fda.gov/consumers/consumer-updates/taking-z-drugs-insomnia-know-risks. Waller, Derek G., Anthony P. Sampson. Anxiety, obsessive-compulsive disorder and insomnia. Medical Pharmacology and Therapeutics. Fifth Edition. 2018. https://www.sciencedirect.com/science/article/pii/B9780702071676000208. Wikipedia. Nonbenzodiazepine. Accessed November 30, 2022. https://en.wikipedia.org/wiki/Nonbenzodiazepine. Z-Drug. ScienceDirect. 2022. Accessed November 30, 2022. https://www.sciencedirect.com/topics/neuroscience/z-drug. Site Links VISIT US ONLINE— WEBSITE: https://www.easinganxiety.com— YOUTUBE (Easing Anxiety): https://www.youtube.com/easinganxiety— YOUTUBE (Benzo Free): https://www.youtube.com/benzofree PLEASE LET US KNOW WHAT YOU THINK— COMMENT: On this video in YouTube— COMMENT: On the blog post on our website— FEEDBACK FORM: https://www.easinganxiety.com/feedback— EMAIL: feedback@easinganxiety.com SUPPORT US— Make a Donation: https://www.easinganxiety.com/donate Podcast Summary This podcast is dedicated to those who struggle with side effects, dependence,
The Z-drugs: Ambien. Lunesta. Sonata. What are these? Are they benzos? Hypnotics? When did they hit the market? Can they cause dependence? Withdrawal? BIND? These questions and more will be discussed in our feature today. In today's episode, we focus on nonbenzodiazepines, or Z-drugs. How are they like benzodiazepines, and how are they different? We also answer some questions about dosage, duration, and rebounding and we hear a story of struggle from Tulsa, Oklahoma. https://www.easinganxiety.com/post/z-drugs-the-other-benzos-an-in-depth-look-at-ambien-lunesta-and-sonata-bfp111Video ID: BFP111Chapters 00:00 INTRODUCTION02:09 My Podcast Voice05:33 Progress on Website06:33 Peer Support Training Update09:10 Struggles, Symptoms, and the Podcast14:47 A reason why, or just coincidence? 18:16 MAILBAG18:58 Does dosage or duration matter? 21:24 Rebound from medical procedures?24:31 BENZO STORY32:28 FEATURE: Z-drugs34:38 What are Z-drugs?36:00 When did Z-drugs hit the market?36:36 Do Z-drugs act like BZDs on the body?37:54 Z-drugs often partnered with BZDs39:46 What are Z-drugs prescribed for?40:07 The Quest for the Magic Pill42:04 Are Z-drugs less likely to cause symptoms?45:06 What are the Z-drug side effects?47:02 Are Z-drug symptoms different?48:20 How to taper from Z-drugs?49:05 BZD and Z-drug Terminology51:48 MOMENT OF PEACE Resources The following resource links are provided as a courtesy to our listeners. They do not constitute an endorsement by Easing Anxiety of the resource or any recommendations or advice provided therein. FEATURE: Z-drugsAshton, C. Heather. Benzodiazepines: How They Work and How to Withdraw (aka The Ashton Manual). 2002. Accessed April 13, 2016. https://easinganxiety.com/ashton Brandt J, Leong C. Benzodiazepines and Z-Drugs: An Updated Review of Major Adverse Outcomes Reported on in Epidemiologic Research. Drugs R D. 2017 Dec;17(4):493-507. doi: 10.1007/s40268-017-0207-7. PMID: 28865038; PMCID: PMC5694420. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694420/. Foster, D E. Benzo Free: The World of Anti-Anxiety Drugs and the Reality of Withdrawal. Erie, CO: Denim Mountain Press, 2018. https://easinganxiety.com/book Kay, Abigail L. et al. Drug Abuse, Dependency, and Withdrawal. Therapy in Sleep Medicine. 2012. https://doi.org/10.1016/C2009-0-40426-4. Schifano F, Chiappini S, Corkery JM, Guirguis A. An Insight into Z-Drug Abuse and Dependence: An Examination of Reports to the European Medicines Agency Database of Suspected Adverse Drug Reactions. Int J Neuropsychopharmacol. 2019 Apr 1;22(4):270-277. doi: 10.1093/ijnp/pyz007. PMID: 30722037; PMCID: PMC6441128. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441128/. U.S. Food & Drug Administration. Taking Z-drugs for Insomnia? Know the Risks. Last Updated April 30, 2019. Accessed November 30, 2022. https://www.fda.gov/consumers/consumer-updates/taking-z-drugs-insomnia-know-risks. Waller, Derek G., Anthony P. Sampson. Anxiety, obsessive-compulsive disorder and insomnia. Medical Pharmacology and Therapeutics. Fifth Edition. 2018. https://www.sciencedirect.com/science/article/pii/B9780702071676000208. Wikipedia. Nonbenzodiazepine. Accessed November 30, 2022. https://en.wikipedia.org/wiki/Nonbenzodiazepine. Z-Drug. ScienceDirect. 2022. Accessed November 30, 2022. https://www.sciencedirect.com/topics/neuroscience/z-drug. The PodcastThe Benzo Free Podcast provides information, support, and community to those who struggle with the long-term effects of anxiety medications such as benzodiazepines (Xanax, Ativan, Klonopin, Valium) and Z-drugs (Ambien, Lunesta, Sonata). WEBSITE: https://www.easinganxiety.comMAILING LIST: https://www.easinganxiety.com/subscribe YOUTUBE: https://youtube.com/@easinganx DISCLAIMERAll content provided by Easing Anxiety is for general informational purposes only and should never be considered medical advice. Any health-related information provided is not a substitute for medical advice and should not be used to diagnose or treat health problems, or to prescribe any medical devices or other remedies. Never disregard medical advice or delay in seeking it. Please visit our website for our complete disclaimer at https://www.easinganxiety.com/disclaimer. CREDITSMusic provided / licensed by Storyblocks Audio — https://www.storyblocks.com Benzo Free Theme — Title: “Walk in the Park” — Artist: Neil Cross PRODUCTIONEasing Anxiety is produced by…Denim Mountain Presshttps://www.denimmountainpress.com ©2022 Denim Mountain Press – All Rights Reserved
In this collaboration with Bu Zhi Dao, we will be releasing a short ELI5 series on Web3 topics. Ray Tong, a long-time crypto investor, breaks down the concept of Web3, stablecoin, the metaverse, and popular buzzwords. Meet Ray and other experts at Taipei Blockchain Week! To purchase tickets for this event, please go to www.taipeiblockchainweek.com. To join BZD, sign up at https://buzhidao.tw. Please support the Taiwanren project by leaving a review and subscribing. 讓我們一起加油! IG: @taiwanren.coEmail: hello@taiwanren.coSupport the show: http://patreon.com/taiwanrenSee omnystudio.com/listener for privacy information.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.25.513689v1?rss=1 Authors: Adel, S. S., Evans-Strong, A., Clarke, V. R. J., Maguire, J., Paradis, S. Abstract: Previously we demonstrated that intra-hippocampal infusion of purified, Semaphorin 4D (Sema4D) extracellular domain into the mouse hippocampus rapidly promotes formation of GABAergic synapses and decreases seizure susceptibility in mice. Given the relatively fast action of Sema4D treatment revealed by these studies, we sought to determine the time course of Sema4D treatment on hippocampal network activity using an acute hippocampal slice preparation. We performed long-term extracellular recordings from area CA1 encompassing a 2 hour application of Sema4D and found that hippocampal excitation is suppressed hours following treatment. We also asked if Sema4D treatment could ameliorate seizures in an acute seizure model: the kainic acid (KA) mouse model of Status Epilepticus (SE). We demonstrate that Sema4D treatment suppresses seizures and lessens benzodiazepine (BZD) insensitivity which is a hallmark of refractory SE. Lastly, we sought to explore alternative methods of Sema4D delivery to hippocampus and thus created an Adeno Associated Virus expressing the extracellular domain of Sema4D. Our data reveal that virally delivered, chronically overexpressed Sema4D extracellular domain promotes GABAergic synapse formation and suppresses seizure activity similar to the actions of purified Sema4D protein. These results provide proof of concept that Sema4D-mediated GABAergic synapse development could combat BZD insensitivity in intractable forms of epilepsy, and that viral delivery of Sema4D is an efficacious and promising delivery method. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
In this collaboration with Bu Zhi Dao, we will be releasing a short ELI5 series on Web3 topics. Tiffany Lai kicks off this series by introducing us to the very first Taipei Blockchain Week and and breaking down the 'Dao' of Bu Zhi Dao. To purchase tickets for this event, please go to www.taipeiblockchainweek.com. To join BZD, sign up at https://buzhidao.tw. Please support the Taiwanren project by leaving a review and subscribing. 讓我們一起加油! IG: @taiwanren.coEmail: hello@taiwanren.coSupport the show: http://patreon.com/taiwanrenSee omnystudio.com/listener for privacy information.
Zapraszamy na kolejny wykład w ramach wydarzenia „Maraton wykładową z Deltą”, podczas którego można usłyszeć o informatyce, matematyce, fizyce oraz astronomii. dr Bartłomiej Bzdęga – pasjonat, popularyzator i nauczyciel matematyki, opiekun finalistów i laureatów Olimpiady Matematycznej, członek Polskiego Towarzystwa Matematycznego i Stowarzyszenia na rzecz Edukacji Matematycznej, współzałożyciel i przewodniczący Wielkopolskiej Ligi Matematycznej, redaktor kącika olimpijskiego w miesięczniku ,,Delta”, starszy wykładowca na Wydziale Matematyki i Informatyki Uniwersytetu im. Adama Mickiewicza w Poznaniu, nauczyciel matematyki w VIII LO w Poznaniu. Materiał dostępny dzięki współpracy z czasopismem Delta http://www.deltami.edu.pl/ https://www.facebook.com/Delta.czasopismo Znajdź nas: https://www.youtube.com/c/WszechnicaFWW/ https://www.facebook.com/WszechnicaFWW1/ https://anchor.fm/wszechnicaorgpl---historia https://anchor.fm/wszechnica-fww-nauka https://wszechnica.org.pl/
The Pharm So Hard Podcast: An Emergency Medicine and Hospital Pharmacy Podcast
Alcohol withdrawal syndrome (AWS) is a disease commonly treated in the emergency department, with~5% of cases leading to delirium tremens. In patients with a history of AWS, decreased GABA-A receptor sensitivity to GABA agonists may causebenzodiazepine (BZD) monotherapy to be ineffective. Patients may experience increase in morbidity and mortality due to escalated doses of benzodiazepines. […] The post Episode 71. Pushing P! Phenobarbital for Alcohol Withdrawal Syndrome appeared first on The Pharm So Hard Podcast.
In this episode we have two guests from Australia. We have Erin Oldenhof who is a doctor of psychology (clinical) candidate, at the School of Psychology, Deakin University, Geelong and a benzodiazepine counsellor in Melbourne. We are also joined by Dr Petra Staiger who is an associate professor, School of Psychology, Deakin University. Paper: Role of the prescriber in supporting patients to discontinue benzodiazepines: a qualitative study https://doi.org/10.3399/BJGP.2020.1062 (https://doi.org/10.3399/BJGP.2020.1062) The introduction of prescription monitoring programmes (PMPs) has highlighted the need for increased support and guidance to ensure GPs improve on current deprescribing practice. This study revealed the importance of GPs understanding how to empower patients through patient-centred care, to foster a willingness to try reducing, build motivation, and promote confidence in the patients' ability to reduce. By understanding the patient experience with their prescriber involved in long-term BZD use, this study advances current knowledge of the ‘patient-centredness' of deprescribing interventions and offers GPs clearer guidance on how to deliver these strategies effectively.
Cns-- anti-anxiety drugs-- BZD-- lorazepam --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app
Materiał jest przeznaczony dla profesjonalistów medycznych.Benzodiazepiny (BDZ) są lekami, które przez lata były nadużywane. Z uwagi na ich potencjał uzależniający oraz potencjalne działania niepożądane bardzo ważne jest, aby lekarz rodzinny znał aktualny stan wiedzy dotyczący wskazań i środków ostrożności w przypadku leczenia pacjenta BDZ.Opracowany dokument jest próbą usystematyzowania podstawowej wiedzy o działaniu, wskazaniach oraz innych istotnych aspektach stosowania BDZ. Podsumowaniem dokumentu jest „Dziesięć przykazań stosowania benzodiazepin dla lekarza rodzinnego” – spis najważniejszych uwag o tych lekach, istotnych z punktu widzenia lekarza rodzinnego.
Status Epilepticus with Special Guest: Karen Berger, PharmD, FCCM, BCPS, BCCCPShow notes: https://pharmacytodose.files.wordpress.com/2019/10/status-epilepticus-show-notes-1.pdfReferences: https://pharmacytodose.files.wordpress.com/2019/10/status-epilepticus-references.pdf6:02 –Karen’s interest in SE; 7:35 – What is SE?; 9:32 – Further classifications of SE?; 10:37 – Patient presentation; 11:27 – Can the presentation change?; 13:35 – Any risk factors for SE?; 14:45 – Medication-induced SE; 15:40 – Prompt non-AED treatment for SE?; 17:06 – Empirically treat Wernicke’s?; 18:35 – Preferred BZD for initial treatment of SE?; 20:44 – If they don’t respond to an AED, do you avoid/discontinue using these agents?; 23:08 – Convincing providers to give larger BZD doses?; 26:53 – BZD dosing if a patient uses alcohol or BZD?; 27:37 – First-line AED for patients in SE?; 30:34 – Difficulty with high quality research in SE?; 31:46 – Are there specific patient populations or disease states where you prefer or avoid a specific AED?; 33:04 – Why is timely treatment so important?; 34:25 – General information on first-line AED agents; 47:20 – Where to find evidence-based dosing recommendations for SE?; 49:49 – Appropriate TDM of AED; 53:55 – Increase dose or add another AED?; 55:53 – How to improve time to AED administration for SE?; 59:04 – Review of IV anesthetic infusions for refractory SE; 64:27 – Tips/Tricks for Pharmacists treating SE; 65:40 – Take-home pointsPharmacyToDose.Com@PharmacyToDose on Twitter/InstragramPharmacyToDose@Gmail.com
Sleep in the ICU with Special Guest: Mojdeh Heavner, PharmD, BCPS, BCCCP4:55 – 10:00 – How did Mojdeh first become interested in sleep?; 10:00 – 13:40 – Why is sleep disruption so bad for ICU patients?; 14:11 – 15:31 – How does sleep deprivation affect clinical outcomes?; 15:35 – 19:13 – How do we know ICU patients have issues with sleep?; 19:45 – 24:38 – Is there a relationship between sleep deprivation and delirium; 24:50 – 30:30 – Risk factors for sleep deprivation; 30:48 – 32:35 – What do the PAD-IS guidelines recommend regarding sleep assessment?; 32:37 – 34:00 – What do we use for sleep assessment currently?; 34:00 – 37:12 – What options are available to assess sleep in ICU patients?; 37:20 – 38:30 – Can we rely on family to bring up sleep related issues?; 38:45 – 44:15 – Non-pharmacologic management of sleep disruption; 44:20 – 54:21 – Pharmacologic interventions for sleep promotion; 54:30 – 55:45 – What to do with the patient who has taken BZD chronically for sleep at home?; 55:45 – 58:10 – Does your approach for sleep management change for patients with chronic insomnia?; 58:12 – 60:09 – Importance of multi-disciplinary involvement with sleep; 60:10 – 63:20 – Role of Pharmacist in Sleep Promotion; 63:20 – 65:00 – Take-home points PharmacyToDose.Com@PharmacyToDose on Twitter/InstagramPharmacyToDose@Gmail.com
Neste episódio do PQU Podcast apresento e comento um estudo sobre a relação presumida entre uso de BZD por pessoas com mais de 65 anos e ocorrência de quadro demencial, cujos resultados foram divulgados de forma distorcida pela mídia e repercutidos à exaustão nas redes sociais.
Kurt Wessling, Director of Sales at Jackson Systems The Barometric Zone Damper (BZD) from Jackson Systems eliminates the need for a bypass damper in residential zoning systems. The BZD damper works like any standard damper with one exception – the BZD has been designed with a blade that is controlled by an actuator and that will also respond to static pressure Brought to you By:
22.01.2010, IMPART (ul. Mazowiecka 17) - The 2nd installment of “Wibracje Taneczne / Dance Vibrations” invited Teatr Dada von Bzdülöw (Katarzyna Chmielewska & Leszek Bzdyl) and SzaZa (Paweł Szamburski & Patryk Zakrocki) for the Wrocław premiere of their collaborative project: “Caffè Latte.” Download: wt02-caffe-latte.mp4 (640×360 / H.264 / AAC / 88.98MB / 9:21) LQ version [...]
This episode of “From the Archive” series brings you another recording from the WrocławNonStop 2007. This time it is a dance performance. The title is “Magnolia,” performed by Dada von Bzdülöw. This piece was presented as part of “Dance Vibratione” (Wibracje Taneczne) on 25.06.2007 at Scena na Świebodzkim (pl. Orląt Lwowskich 20c). Download: magnolia.mp4 [...]