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TISS is a weekly podcast where Varun, Kautuk, Neville & Aadar discuss crazy "facts" they find on the internet. Come learn with them... or something like that.This week, the boys are diving into a hilarious episode of 'Desperate ex's, JCB & Keanu Reaves Scam'To support TISS, check out our Instamojo: www.instamojo.com/@TISSOPFollow #TISS Shorts where we put out videos: https://bit.ly/3tUdLTCYou can also check out the podcast on Apple podcast, Spotify and Google podcast!https://shorturl.at/hfQZXhttp://apple.co/3neTO62http://spoti.fi/3blYG79http://bit.ly/3oh0BxkCheck out the TISS Sub-Reddit: https://bit.ly/2IEi0QsCheck out the TISS Discord: / discord Buy Varun Thakur's 420 Merch - http://bit.ly/2oDkhRVSubscribe To Our YT Channels:Varun - https://bit.ly/2HgGwqcAadar - https://bit.ly/37m49J2Kautuk - https://bit.ly/3jcpKGaNeville - https://bit.ly/2HfYlWyFollow Us on Instagram:Varun - / varunthakur Aadar - / theaadarguy Kautak - / cowtuk Neville - / nevilleshah. Chapters:00:00 - Teasing Bawa01:26 - Bawa's Birthday02:43 - Welcome & Introduction03:02 - What is Hyping?03:25 - Indigo Flight Canceled: "IT WAS MY WEDDING"04:04 - Indigo bad-dua04:47 - Driving to Bangalore05:22 - Sorry Bangalore07:34 - Episode Introduction07:46 - Dhurandar References08:26 - Dhurandar Review11:26 - Indian Films with Ajit Doval Obsession12:35 - Ajit Doval in Yashraj spy universe13:00 - Dhurandar is Animal 2.014:46 - Action Seq on Old Hindi songs16:50 - Toxicity needed for the movie17:20 - Violence in a movie19:00 - Akshaye Khanna Killed the movie?20:39 - Rest of the cast21:33 - Sanju Baba Accent25:58 - Sanju Baba Action while pushing 7027:35 - Longest Ad on Cigarette28:52 - Smoking in Theatre30:59 - Dhurandhar Pt. 232:28 - Tarantino Verse33:46 - Production Design35:16 - Is it a “Propa” Film?36:13 - Pakistani Memers37:31 - Destruction of Pakistan in CInema37:56 - Whatsapp News Agency38:41 - Pakistan News Paper on Chat GPT39:48 - AI Robot40:48 - AI F*ck ups (Scottish Footbald)41:57 - Chevrolet Tahoe for $143:49 - AI Watch Face Generation Attempt44:36 - Indigo Anonymous45:05 - Airlines Pilot Norms46:20 - Pilot Shortage Issues46:51 - Indigo's Master Plan47:33 - Right to Compensation for Passengers48:06 - Air India Misplaced Boeing49:21 - Indigo Airport Chaos50:10 - Juggad to board a flight50:39 - caught the Wrong Guy52:51 - Indigo Ground Staff53:00 - Gurgaon Indigo Staff53:48 - Indigo Management Retribution54:34 - Indigo's apology55:08 - High Charges for Other Flight Tickets56:23 - Why Indigo Suffered?58:16 - Arnab asks central govt.59:00 - Pakistan's Solution1:01:12 - Bangsy's Trauma1:02:07 - Reading Superchats1:03:48 - Sumukhi Cameo1:13:29 - Reading SuperchatsThumbnail - Anjali Handa
This week on the Naturally Nourished Podcast, Ali shares highlights from her recent experience at Hack Your Health, where she presented on the main stage on Resilience in a Time of Toxicity. Tune in for an inside look at the cutting-edge biohacking and longevity tools shaping the future of health and wellness—from detoxification and metabolic resilience to nervous system regulation and performance optimization. In this episode, discuss emerging wellness trends, what's truly promising versus overhyped, and how functional medicine continues to bridge the gap between innovation and real-world application. Hear our thoughts on fulvic and humic acid supplements, EMF mitigation tools, quantum energy, and more! Also in this episode: Naturally Nourished Academy - Early Bird Pricing ends 12/31! 10 Day Detox - Free Masterclass January 5th Free Keto Reset Masterclass January 7th Episode 449 Hack your Health with Guest Robin Switzer Vendor Highlights from Hack Your Health Pluck Seasonings Masa Chips Beefys Own Tallow Chips Yeehaw Snacks (Becki's husband Byron's new company!) Noble Origins use code ALIMILLERRD Sea Level Shots KetoMojo Beam Minerals Ali's Lecture Episode 394 The Human Electrical Force Episode 385 Reducing Exposure and Impact of Glyphosate Episode 391 Microplastics New Technology at Hack Your Health PEMF Mats Aires Tech BrainTap Avacen Vibration Plates Lifewave Patches Sponsors for this episode: This episode is sponsored by Toups & Co, makers of 100% natural skincare and makeup featuring ingredients like grass-finished tallow, organic botanicals, and organic cold pressed plant oils. They never use synthetic chemicals, toxins, fillers, artificial colors or synthetic fragrances. They are a family-owned brand committed to natural living and ingredient transparency--guided by the same unwavering commitment to purity and quality that has changed their own family's health for the better. Carefully selected powerful organic ingredients that nourish for your best skin health. Nourishes with essential fatty acids to balance the skin's microbiome. Use code ALIMILLERRD to save.
Dive into the surprising and often dangerous world of psychoactive substances and our furry friends. This episode explores historical animal experiments with drugs like LSD and psilocybin, real-life cases of accidental pet poisonings from marijuana, amphetamines, and more, veterinary insights on toxicity risks, and why giving psychedelics or recreational drugs to dogs and cats is never a good idea—highlighting symptoms, treatments, and safer alternatives.▶️ *[WORK WITH ME]* https://RobbJarrett.net▶️ *FREE* Personal Brand Starter Kit :: https://www.medialabb.net/brandkit*[SUBSCRIPTIONS I RECOMMEND]*ABOBE CREATIVE SOFTWARE - VIDIQ (AI Creation and SEO) - https://vidiq.com/robbjarrett Motion Array (Assets) - Envato (Assets) - OPENART (AI Creation Tools)BEACONS: https://beacons.ai/signup?c=robbjarrett*[PRODUCTS I RECOMMEND]*SM7B Microphone - https://amzn.to/47AuKREMV7+ Microphone - https://amzn.to/3V7LRmABLUE YETI Microphone - https://amzn.to/3V7LRmAOBSBOT Webcam - https://amzn.to/4mcWhMFDJI Action Cam - https://amzn.to/3V44gk7DJI OSMO Gimbal - https://amzn.to/3V44gk7NEEWER Lights - https://amzn.to/4pfvMJe
Welcome back to the Oncology Brothers podcast! In this episode, we continue the CME series on HER2-positive GEJ and gastric cancer, shifting focus to the essential topic of treatment toxicity management. We're joined by two leading experts: Dr. Geoffrey Ku from Memorial Sloan Kettering and Dr. Shruti Patel from Stanford University. Building on their previous discussion of upper GI treatment algorithm with Dr. Rutika Mehta, this episode delves into the practical realities of managing patients on complex regimens. Drs. Ku & Patel break down the side effect profiles across the treatment continuum—from frontline trastuzumab-based combinations to emerging therapies like zanidatamab—and provide actionable strategies for community oncologists. Episode Highlights: • Practical management of frontline side effects with FOLFOX/XELOX chemotherapy plus trastuzumab and pembrolizumab • Reality check on trastuzumab cardiotoxicity: incidence rates and monitoring protocols in gastric vs. breast cancer • Immune-related adverse events with checkpoint inhibitors: what's common vs. rare in GI cancers • Critical insights on zanidatamab's synergistic diarrhea toxicity and mandatory prophylaxis strategies • TDXd (Enhertu) in second-line: moving beyond ILD fears to address frequent cytopenias and marrow management • Expert consensus on infusion reaction management for novel biologics • The importance of managing baseline symptoms in patients with dysphagia and nausea This episode bridges the gap between trial data and clinical practice, offering real-world wisdom on keeping patients on effective therapies through proactive toxicity management. Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Don't forget to subscribe for our complete CME series covering treatment algorithms, FDA approvals, and practical management strategies! Accreditation/Credit Designation Physicians' Education Resource®, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Physicians' Education Resource®, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Acknowledgment of Commercial Support This activity is supported by an educational grant from Jazz Pharmaceuticals, Inc. Link to gain CME credits from this activity: https://www.gotoper.com/courses/navigating-the-adverse-event-landscape-in-her2-gea-therapy
Combination regimens improve survival in advanced EGFR-mutated NSCLC, but they also increase toxicity. Jorge Nieva, MD, shares how he talks with patients about potential adverse events. He describes the options available for prophylaxis and how he treats the toxicities that do arise.
As the year is coming to a close I reflect on my relationships and experience of my life this year. Toxicity is definitely one of them, I’ve been the toxic friend and have had a fair share of my own, here are tips/advice of having healthy friendships See omnystudio.com/listener for privacy information.
In this eye-opening episode of The Lisa Fischer Said Podcast, Lisa Fischer speaks with Heather Gordon about her unconventional path to healing after years of unexplained symptoms. Heather shares how concerns around breast implant illness led her to uncover deeper root causes—including fragrance toxicity, long COVID, nervous system dysregulation, and viral reactivation—and how the nicotine patch protocol became a surprising turning point in her recovery. Together, they explore why many women are misdiagnosed in midlife, the hidden health risks of synthetic fragrances, the role of circadian rhythm and light exposure, and why true wellness often requires questioning mainstream advice. This candid conversation offers hope, practical insights, and a new lens on women's health, healing, and personal empowerment. WEBSITE: https://projectgoods.com INSTAGRAM: https://www.instagram.com/prettysickheather/ FACEBOOK: https://www.facebook.com/prettysickheather/ EPISODE SPONSOR: https://www.davidsburgers.com/ EPISODE SPONSOR: https://marlsgate.com LISA'S LINKS: Lisa Fischer Said Academy: https://lisafischersaid.com/academy/ Website: lisafischersaid.com For more information on group intermittent fasting coaching with Lisa, email fasting@lisafischersaid.com For more information on one-on-one or group health coaching with Lisa, email healthcoaching@lisafischersaid.com Podcast produced by clantoncreative.com
In this episode, I talk with Dr. Jeremiah Sturgill, a down-to-earth orthodontist from Johnson City, Tennessee, who's built one of the most impressively scaled, efficiently run, single-owner practices in the country. But what makes Jeremiah stand out isn't just the growth—it's the way he's done it: with humility, grit, and a relentless focus on investing in people and systems.We dive into how he transformed a modest, well-run legacy practice into a multi-location, multi-doctor machine—while still making time for real estate ventures, short-term rentals, and even a boutique marketing firm. You'll hear how he staffs a 15-chair main office with surgical efficiency, manages a rotating team across three locations, and still finds the time to build custom homes with a team of craftsmen who love what they do. If you're looking to scale, stabilize, and stop micromanaging, this is a masterclass.QUOTES“You will never get fired for making a mistake. You will get fired for not owning it and blaming someone else.” — Dr. Jeremiah Sturgill“You can't control everything. You can try your best, but when you strangle your business, you kill its potential.” — Dr. Jeremiah SturgillKey TakeawaysIntro: Wagon Wheel, small towns, and big growth (00:00)The 16-year-old decision that led to ortho (01:35)How he grew a standard practice into a national standout (03:41)Practice structure: 3 locations, 17–18 doctor days/week (05:03)The secret: efficiency, not just scale (06:02)His “open-hand/closed-hand” culture system (08:06)Toxicity vs. mistakes: the cultural line in his practice (09:26)Why age doesn't predict maturity—and why gratitude matters (10:58)Office “cultural anchorage” and scaling team values (13:51)Comparing small vs. large teams: impact, culture, and coverage (15:19)How humility and faith ground his leadership approach (17:27)Real estate beginnings: realtor at 18, flips in dental school (19:41)Short-term rentals, storage units & the road to REPS (21:45)Why doctors must partner with experts in real estate (23:11)His custom home design firm—and love of elite tradespeople (29:24)Boutique SEO wins: 30% increase in new patient exams (28:10)Launching GoUnicornStrategy.com for ortho marketing (30:51)Final thoughts: relationships over returns, every time (33:29)Additional ResourcesIf you've ever wondered how to grow a thriving ortho practice without burning out or losing your culture—Jeremiah's story proves it can be done. It's not luck. It's leadership, systems, and people-first thinking.
Joyce talks about the dangers of radical Islam, and how it has come to America. She talks about foreign nationals who hate America being allowed into the country, the leader of the largest Mosque in Florida being known for preaching hatred for against Jews and Christians. CAIR files a lawsuit against Governor DeSantis claiming the his executive order listing CAIR as a terrorist organization is unconstitutional.The cost of addiction. Congressman Bryon Donalds calls in to the show to talk about radical Islam and the plan to use American laws and sympathy against us. He talks about standing up for western civilization and values, the rising cost of living in Florida and how he plans to bring down prices as the next Governor of Florida. He also talks about maintaining conservative values and training kids to become economically viable. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Expert physician researcher Sunil Wimalawansa explains why Vitamin D plays a critical role in immune system function, the physiology various forms of vitamin D and how to ensure you keep a level compatible with optimal health.Dr Sunil J. Wimalawansa, MD, PhD is a globally respected clinician-scientist, educator, over three decades of leadership in endocrinology, osteoporosis, metabolic bone disease, and nutrition. He served as professor and chief of endocrinology at leading U.S. medical institutions, including the Robert Wood Johnson Medical School/Rutgers University.CONSULT DR MAXInitial consult - https://www.drmaxgulhane.com/offers/5jfDvLyH/checkoutSUPPORT MY WORK
In this episode of the Oncology Brothers podcast, we dived deep into the world of antibody drug conjugates (ADCs) in non-small cell lung cancer (NSCLC). We welcomed Dr. Jacob Sands from the Dana-Farber Cancer Institute to discuss the latest ADCs approved for NSCLC, including Trastuzumab deruxtecan (TDXd), Datopotamab deruxtecan (Dato-DXd), and Telisotuzumab Vedotin (Teliso-V). We explored the side effect profiles of these therapies, focusing on critical toxicities such as interstitial lung disease (ILD), mucositis, and peripheral neuropathy. Dr. Sands shared valuable clinical pearls on managing these adverse events, emphasized the importance of proactive monitoring and patient education. Key topics covered in this episode: • Overview of ADCs and their role in NSCLC treatment • TDXd: alopecia, ILD, fatigue, nausea/vomiting • Dato-DXd: cytopenias, mucositis, dry eyes • Teliso-V: peripheral neuropathy, fatigue, peripheral edema • The evolving landscape of ADCs and future directions in lung cancer treatment Whether you're a healthcare professional or someone interested in oncology, this episode provides essential insights into the management of side effects associated with these innovative therapies. Tune in for practical advice and expert opinions that can enhance patient care in the community setting. Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Don't forget to like, subscribe, and hit the notification bell for more episodes on practice-changing discussions in oncology! #ADC #NSCLC #TDXd #DatoDXD #TelisoV #ToxicityManagement #OncologyBrothers
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Welcome to the Oncology Brothers podcast! In this episode, we welcomed Dr. Neil Iyengar and Dr. Emily Gallagher, to dive deep into the world of PIK3CA and AKT pathway inhibitors for hormone receptor-positive (HR+) metastatic breast cancer. We discussed the latest approvals, including Inavolisib, Alpelisib, and Capivasertib, and explored their common side effects such as hyperglycemia, rash, and gastrointestinal issues. Our experts shared practical management strategies, dosing considerations, and the importance of patient education to ensure safe and effective treatment. Key topics covered in this episode: • Overview of PIK3CA and AKT inhibitors • Common side effects and their management • The significance of proactive patient education • Dosing strategies and when to consider dose modifications • Insights on managing hyperglycemia and gastrointestinal symptoms This episode is packed with valuable information to enhance your understanding of these important therapies in the breast cancer world. Don't forget to subscribe for more episodes on treatment algorithms, toxicities, and the latest in oncology! #PI3Kinhibitors #BreastCancer #Hyperglycemia #ToxCheck #MetastaticBC #OncologyBrothers #TargetedTherapy
Let's be real blunt here: Can eating liver kill you. Is it Toxic???Seriously, that is the view today among nutritional counselors and dieticians.Are they wrong ?It is an easy fear-based accusation to make because everything 'can be toxic' it always about the dose, the amount you consume over time ... of anything.Let's discuss why this hysteria is more damaging advice then it is a prudent recommendation.Have people died eating liver: Yes.but they were Arctic explorers for the most part who consumed polar bear liver.Podcast: https://www.buzzsprout.com/482971/episodesFacebook Group about Keto: https://www.facebook.com/groups/ketonaturopath/BLOG: https://ketonaturopath.com/Pinterest: https://www.pinterest.com/ketonaturopathYouTube channelwww.youtube.com/ketonaturopathJudi's NEW cooking channelKeto Naturopath Kitchenhttps://www.youtube.com/c/KetoNaturopathKitchen——————————— OUR COURSE ——————————PSMF 30 day course: https://www.thebiointegrationcode.com/courses/PSMFChallenge——————————— WHERE WE GET OUR WINE (an affiliate link) ——————————Dry farm wineswww.dryfarmwines.com/ketonaturopath—————————Where we get our Genome SNP analysis done ———————————Strategenehttps://bit.ly/3iqCfka————————————Where you can get your labs done——————————————https://www.UltaLabTests.com/ketonaturopath———————————— WHERE WE BUY OUR SUPPLEMENTS ————————————Wellevate: https://wellevate.me/karl-goldkamp or call them: 855-935-5382How to use Wellevate https://youtu.be/1ulC0LLIc5cWhy get a Wellevate account to get your supplements??1. They have more brands than anywhere else to choose from;2. Their prices are 20 -50% lower than anywhere else; compare and you'll see3. This is where most physicians have their account4. Been in existence for nearly 30 years working with physicians and health practitionersHow to get your Wellevate account1. Open the link: https://wellevate.me/karl-goldkamp and registered2. Reply to their verification email3. Explore their website. And make sure you subscribe to my channel!CONTACT:Questions, INQUIRIES:Karl: drgoldkamp@ketonaturopath.comJudi: support@ketonaturopath.comSharing the metabolic strategy we used to regain our health and discoveries that will help you reclaim your vigor, and physique faster than you thought possible! No tricks, No marketing malarky, just the honest opinion of our own experience, 16 years of clinical medical practice, and having to save our own lives.
In this powerful episode of Beyond the Pain, I'm joined by Dr. Sean McCaffrey, who shares his remarkable journey from aspiring lawyer to dedicated healer — a path shaped by personal loss, intuition, and a family legacy in medicine.Sean breaks down the true nature of chronic pain and why it's never just about the tissues. He explains how lasting healing requires addressing the mechanical, emotional, and nutritional components of the body — and why conventional approaches so often miss the mark.We explore the role of toxicity and inflammation, the healing potential of nutritional strategies and fasting, and the profound influence of the subconscious mind in either amplifying or reducing pain. Sean also shares incredible success stories from his clinic, demonstrating what's possible when you address the real root causes instead of chasing symptoms.If you've ever doubted your ability to heal, this episode will challenge your beliefs — and inspire new hope.Connect with Sean McCaffreyWebsite: https://www.mccaffreyhealth.com/Facebook: https://www.facebook.com/McCaffreyHealthCenter/YouTube: https://www.youtube.com/@dr.seanmccaffrey4616Instagram: https://www.instagram.com/drseanmccaffrey/?utm_source=qr#X: https://x.com/mccaffreyhealth?t=lqPanXvg9PwZaH_1hRtlVAConnect with LeighWebsite: https://www.bodychek.co.uk/Pain-Free Plate (Free Guide): https://www.bodychek.co.uk/freepainguide/Leigh's Courses:StickAbility: https://stickabilitycourse.com/Mastering Client Transformation (for practitioners):https://www.functionaldiagnosticnutrition.com/mastering-client-transformation/
Oncologist and health care executive Yousuf Zafar discusses his article, "When cancer costs too much: Why financial toxicity deserves a place in clinical conversations." Yousuf explains the concept of "financial toxicity," a severe burden caused by both direct medical bills and indirect costs (like time off work or child care) associated with cancer treatment. He reveals the sobering statistic that over forty percent of patients deplete their savings within two years, but emphasizes that this distress is more than just a financial problem: it directly compromises treatment adherence, forcing some to skip appointments or forgo prescriptions. Yousuf highlights the critical lack of cost transparency in oncology and makes the case for why clinicians must proactively screen for financial strain just as they would for physical side effects. Discover why these difficult conversations about the cost of cancer are essential for improving patient outcomes and quality of life. Our presenting sponsor is Microsoft Dragon Copilot. Want to streamline your clinical documentation and take advantage of customizations that put you in control? What about the ability to surface information right at the point of care or automate tasks with just a click? Now, you can. Microsoft Dragon Copilot, your AI assistant for clinical workflow, is transforming how clinicians work. Offering an extensible AI workspace and a single, integrated platform, Dragon Copilot can help you unlock new levels of efficiency. Plus, it's backed by a proven track record and decades of clinical expertise, and it's part of Microsoft Cloud for Healthcare, built on a foundation of trust. Ease your administrative burdens and stay focused on what matters most with Dragon Copilot, your AI assistant for clinical workflow. VISIT SPONSOR → https://aka.ms/kevinmd SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended
Most people take vitamin D pills because their doctor, a commercial, or a supplement aisle told them to. But do vitamin D supplements actually improve your health? In this episode, Miles Hassell MD breaks down what the evidence really shows — and why vitamin D sources found in nature may be far more powerful. We dive into the massive gap between blood levels of vitamin D and whether supplements actually work, the risks of "false confidence" in pills, and the often-overlooked benefits of sunlight, food, weight management, and real lifestyle habits. Key Takeaways Supplements rarely improve outcomes. Large, well-designed studies show vitamin D pills generally do not reduce cancer, heart disease, fractures, falls, or total mortality. Natural sources matter. People with naturally higher vitamin D levels (sunlight, diet, activity) live longer and healthier — but synthetic vitamin D doesn't recreate that benefit. The "healthy user effect." Higher vitamin D often reflects healthier habits, not pills. Sunlight is the #1 source. Just 10–15 minutes of midday sun can significantly boost levels and also increases nitric oxide, improves metabolism, and supports cardiovascular health. Supplement benefits are limited. Possible small improvements for respiratory infections and progression from prediabetes to diabetes — but usually too small to be clinically meaningful. Toxicity exists. Over-supplementation or manufacturing errors can cause dangerously high levels and hypercalcemia. Food sources are powerful. Oily fish, cod liver oil, free-range eggs, and sunlight-exposed mushrooms all meaningfully improve vitamin D status. Lifestyle > pills. Exercise, weight management, and whole-food nutrition remain far more impactful than supplements. Get your copy of Good Food Great Medicine, 4th ed.: https://a.co/d/1D6hIYM More references can be found at www.GreatMed.org Would you like Dr. Hassell to answer your question on the air? Contact us! Phone/text: 503-773-0770 e-mail: info@GreatMed.org EIN: 88-326-7056 Write us a letter. We love to hear from you. This podcast is sponsored by our generous listeners. Send questions, comments, and support to: GreatMed.org 4804 NW Bethany Blvd., Suite I-2, #273 Portland OR 97229
Featuring an interview with Dr Matthew Lunning, including the following topics: Reflection on the advances made in chimeric antigen receptor (CAR) T-cell therapy (0:00) Overview of the CAR T-cell therapy administration process (4:40) Opportunities for referral for CAR T-cell therapy (10:05) Selection of a CAR T-cell therapy based on patient characteristics (16:09) Sequencing of CAR T-cell therapy for various non-Hodgkin lymphomas (23:23) Safety regulations and mitigation strategies for adverse events (30:36) Case: A woman in her early 80s with relapsed/refractory (R/R) diffuse large B-cell lymphoma receives lisocabtagene maraleucel (36:16) Case: A man in his early 60s with R/R mantle cell lymphoma receives brexucabtagene autoleucel (43:09) Case: A man in his early 60s with R/R multiple myeloma receives ciltacabtagene autoleucel (49:09) CME information and select publications
Featuring a slide presentation and related discussion from Dr Matthew Lunning, including the following topics: Overview of available chimeric antigen receptor (CAR) T-cell therapies (0:00) Toxicities associated with CAR T-cell therapy (4:03) Mitigation strategies for adverse events (22:02) Novel strategies for outpatient infusion (26:34) Changes to the CAR T-cell therapy safety regulations (30:23) CME information and select publications
Dr Matthew Lunning from the Fred and Pamela Buffett Cancer Center in Omaha, Nebraska, discusses recent updates on the management of toxicities associated with CAR T-cell therapy. CME information and select publications here.
PRIMETIME: Cam Ward vs Shedeur Sanders brings a whole new level of toxicity to Titans For More PRIMETIME coverage follow us here: www.atozsports.com/nashville Podcasts: atozsports.com/podcasts Facebook: https://www.facebook.com/atozsportsnashville Instagram: https://www.instagram.com/atozsports/ Twitter: https://twitter.com/AtoZSports TikTok: https://www.tiktok.com/@atozsportsnashville #AtoZSports #TennesseeTitans #NFLFootball #Titans #NFLUpdates #NFLFootball Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Ryan Feldman from The Poison Lab joins us again to talk about a patient that took... all of it. Like all of it. All gone. Can she be saved?
Feeling worn down by work or wondering if your burnout is more than just stress? You're not alone. In this episode, Lindsey Fuller is joined with Elandria Jackson Charles and Naomi Hattaway for a heartfelt conversation about how our jobs impact our wellbeing—and what to do when things start to feel overwhelming. Together, they explore real stories of burnout and offer gentle, practical tools for tuning into your own needs. Tap into how to recognize the difference between everyday discomfort and true harm, plus find fresh ways to rest and even reclaim joy amid the daily grind. Whether you're considering a career shift, dreaming of consulting, or simply hoping to feel more balanced, this conversation will support you and give you thoughtful steps to move forward.Episode HighlightsExploring Self-Study and Burnout (02:57)The Importance of Nature and Grounding (05:31)Navigating Personal and Professional Seasons (08:22)Tools for Self-Care and Recovery (10:43)The Role of Agency in Time Management (13:47)Creating Protected Time for Wellbeing (16:54)The Power of Naming and Noticing (19:43)Zoom Out Somatic Practice (22:50)Understanding Workplace Dynamics (27:32)Differentiating Misalignment, Dysfunction, and Toxicity (28:49)Navigating the Transition to Consulting (35:20)Naomi and Elandria's Affirmations (43:12) Episode Shownotes: www.weareforgood.com/episode/toxicworkplace//Join the We Are For Good Community—completely free.Join fellow changemakers, share takeaways from this working session, and keep collaborating in a space built for connection, inspiration, and real impact: www.weareforgoodcommunity.com Say hi
What if the greatest victories of your life are not the ones the world celebrates, but the ones no one ever sees? In this episode of The Game Changing Attorney Podcast, Michael Mogill sits down with three-time Olympic gymnast Dominique Dawes to explore the true cost of world-class performance and what it really takes to build a life defined by purpose, not pressure. From her history-making Olympic journey to rebuilding the sport from the inside out, Dominique reveals the sacrifices, struggles, and pivotal moments that shaped her mission to create a healthier culture for the next generation. Here's what you'll learn: Why greatness requires sacrifice and how to decide which sacrifices are actually worth it How to transform pain, pressure, and adversity into a mission that serves others What it takes to build a purpose-driven business without losing yourself or your family in the process If you are striving for excellence that lasts, this conversation will challenge you to rethink what winning really means. ---- Show Notes: 04:56 — Dominique describes the grueling daily training schedule that made her want to quit. 06:45 — She explains why young gymnasts often sacrifice their entire childhood for less than five minutes on the Olympic stage. 08:44 — Dominique shares why gold medals do not make her top ten life moments and what truly matters more. 14:22 — She reflects on signing a lease before the pandemic and pushing through the uncertainty that followed. 17:21 — Dominique discusses expanding her academy and how her daughter telling her she was working too much changed everything. 20:14 — She explains how motherhood shifted her definition of success and forced her to re-evaluate priorities. 24:32 — Dominique talks about why relentless achievement can lead to burnout and what real balance looks like. 32:44 — She contrasts old-school coaching adversity with the healthier culture she's building at her academies. ---- Links & Resources: Dominique Dawes Gymnastics and Ninja Academy Larry Nassar Simone Biles ---- Do you love this podcast and want to see more game changing content? Subscribe to our YouTube channel. ---- Past guests on The Game Changing Attorney Podcast include David Goggins, John Morgan, Alex Hormozi, Randi McGinn, Kim Scott, Chris Voss, Kevin O'Leary, Laura Wasser, John Maxwell, Mark Lanier, Robert Greene, and many more. ---- If you enjoyed this episode, you may also like: 401. AMMA — From Girl Dad to CEO: The Michael Mogill Playbook 293. Elite Athletes — The Mental Edge: How Champions Overcome the Impossible 207. Patty McCord — How to Build a Culture of Freedom and Responsibility
T'was Thanksgiving week and your boys were both stupendously busy with family and FOOD, so instead of going dark we pulled an Ace out of our sleeves and hit you with another CLASSIC ALBUM REVIEW. This time around we're talking about an album that only gets better with time, "TOXICITY" by System of a Down. ENJOY. Merch Store- http://tee.pub/lic/doEoXMI_oPI Patreon- https://www.patreon.com/Artandjacobdoamerica Website- https://artandjacobdoamerica.com/ Network- https://podbelly.com/ Instagram- https://www.instagram.com/artandjacobdoamerica YouTube Channel- https://www.youtube.com/channel/UC0rT6h3N2pWtlkxaqgIvaZw?view_as=subscriber Twitter- https://twitter.com/ArtandJacobDoA1 Facebook- https://www.facebook.com/artandjacobdoamerica/
In this episode, Katie introduces the Own Your Health System, a step-by-step framework distilled from 20+ years of Chinese medicine, healing practice, and real-world experience helping thousands of people transform their physical, emotional, and spiritual health. You'll learn why so many of us are unwell, even though we live longer than ever. Katie breaks down how colonisation, industrialisation, modern lifestyle, tech overload, stress, poor circulation, and lost ancient practices have pulled our bodies out of alignment — and what simple daily habits can pull them back. If you've ever asked yourself: “Why am I ill? What do I do? How do I fit this into my busy life?” — this episode gives you the answers. You'll discover: ✔ Why ancient healthcare systems still matter today ✔ How modern living disrupts your body's natural rhythm ✔ How stagnation, toxicity, and stress accumulate in the body ✔ The #1 cause of modern illness (according to the WHO) ✔ Simple, free practices to improve circulation & reduce symptoms ✔ How to build health routines that actually fit your daily life This episode is perfect for anyone interested in holistic health, Chinese medicine, self-care, stress reduction, sleep improvement, menopause, weight gain, energy, or understanding how to live well in the modern world. Chapters: 00:00 — Why Modern Life Makes Us Sick: The Big Picture 02:25 — The Three Questions Everyone Asks When They're Unwell 05:10 — Why Ancient Healthcare Systems Disappeared 08:00 — Colonisation, Politicisation & the Fragmentation of Health 12:20 — Industrialisation: When We Lost Our Connection to Nature 15:45 — Modernisation & Tech Overload: A Body Out of Sync 20:30 — Accumulation, Toxicity & Why Symptoms Build Over Time 27:00 — What To Do: Aligning Yourself Through Daily Routine 31:40 — How to Improve Circulation (80% of Illness Starts Here) 38:10 — The Own Your Health System Explained + What's Coming Next ------------------------------------------- More information here: https://katiebrindle.com/ Subscribe to my newsletter: https://katiebrindle.com/newsletter-signup/ Buy 'Yang Sheng: The Art of Chinese Self-Healing' at https://www.hayoumethod.com/product/yang-sheng-the-art-of-chinese-self-healing/ Buy the Hayo'u tools at https://www.hayoumethod.com/products/ Hayo'uFit at https://hayoufit.com -------------------------------------------- Join my channel and leave a comment about what you want to see next! Love, Katie Brindle.
In this episode of Hidden Wisdom, Meghan Farner sits down with Steve Pynakker, creator of Mormon Book Reviews and one of the most unique bridge-builders in the religious landscape. Steve shares his lifelong fascination with the Restoration, his journey through evangelical Christianity, atheism, and back into a reconstructed faith, and the spiritual insights he's gained across traditions.Together, Meghan and Steve explore the feminine and masculine elements of religion, personal revelation, the role of mystical experience, faith crises, and why genuine connection with God often requires stepping outside institutional boundaries. They dive into the tension between apologetics and Christlike love, the dangers of zeal without compassion, and the shared work of healing religious division.This heartfelt and challenging conversation invites listeners to seek God beyond labels, recognize the divine image in every person, and cultivate a faith centered on love, humility, and spiritual authenticity.Timestamps & Episode Structure00:00–02:10 | Introduction02:10–07:30 | How Steve Entered the Mormon World07:30–13:00 | Faith Deconstruction and Atheism13:00–16:20 | Looking for Christ Instead of Faults16:20–22:10 | The Ego Death of Faith Crisis22:10–28:00 | Masculine and Feminine in Religion28:00–33:20 | Toxicity, Power, and the Danger of Misused Zeal33:20–38:00 | Responsibility as a Public Voice38:00–44:40 | Where Apologetics Goes Wrong44:40–52:30 | The Mirror: Calling Communities to Repentance52:30–56:40 | The Three Questions That Transform Dialogue56:40–59:00 | Closing Reflections: Love as the Center Thank you for listening to Hidden Wisdom! For more classes, writings, and upcoming events, visit meghanfarner.com. ✨ New Class Now Open: The Language of Heaven: Basic Symbols Discover the foundational symbols of divine communication and deepen your spiritual understanding for FREE! Register here! If this episode brought value to your life, please consider: Donating through Venmo: @Meghan-Farner Subscribing to stay updated Sharing it with someone who would love it Leaving a comment or review to help others find the show Connecting and exploring more resources at meghanfarner.com Thank you for being a part of the Hidden Wisdom community!
Staying focused; Inflammatory Media; "Antifa"; Tyranny; Current events; "Hands-off Leticia? Jacoba?"; Finding the facts; Love for truth; Cancel culture; Stirring up a spirit in the masses; Polio; Healthy body environment; Healing spirit of God; Toxicity; Inspiration; Evidence Jesus existed; Private interpretation?; Homelessness; 2 Thess 3:10 don't work, don't eat; Irrefutable proof?; Social safety net dependency; Adullamites - out of the "way"; Other people's money; Mark Q: Proving Jesus existed - irrefutably; Mark Q: Meaning of "Socialism"; Altars; Corporate capitalism - doesn't die, Golem; Choice remains with the individual; Dependence on community; Logical logos - stay a free people; Harlots, daughters and beasts; Networking; Parrhesia Q: Can we Debate?; Katwellair Q: "Put to Death"?; Stoning?; Binding by love of neighbor; Freewill offerings only; Vengeance belongs to God; Knowing yourself; Strong delusion; Nikki Q: Salvation and being saved?; Salvation or Deliverance; Separation from God; Levels of salvation?; Consequences of sin; Freed from what?; Striving and persevering; Redemption?; Choosing direction; Katwellair Q: Life after death?; Celestial body?; Other dimensions?; Kingdom of heaven is in the moment; The way of God and Christ and Moses; Accessing Holy Spirit; Tree of Knowledge vs Tree of Life; Creatures of Light; Comforting lies; Nikki Q: Blood of Christ? Rom 5:9; Staying with Christ; Repentance; Workers of iniquity; Hearing the cries of your neighbor; Lets God hear you; Obedience; Virtue; Nikki Q: Jesus cancelled our debt?; Paul's audience; Becoming merchandise by covetousness; John 3:17 MIGHT be saved; Accessing salvation; John 5:34; Rom 10:1; Rom 11:14; Christ did His part; We have a part too; Faith compels action unto righteousness; Katwellair Q: Romans 5 - last half; Rom 5:12; Rom 5:19 being made righteous; Gift of faith; Accepting Christ on a spiritual level; Beware of emotional counterfeits of spirit; Early Church activity; Let go of preconceived notions.
Join us on the Programming Lions podcast as we welcome Jonah, a familiar face from our Youth Roundtable debates, to understand his drastic political shift from liberal to communist. In this first part of a two-part series, we explore what led Jonah to embrace communism as a political philosophy, discussing the influences, theories, and motivations behind his transformation. We also delve into the broader trend of young individuals showing interest in communism, addressing common critiques and looking at future possibilities. Stay tuned for an enlightening and thought-provoking discussion. #Communism #YouthPolitics #ProgrammingLionsPodcastShop GSD Affiliates:
Oxygen is one of those therapies that nurses use every single day with almost every single patient. But did you know too much oxygen can actually cause harm? In this episode, you'll learn: What oxygen toxicity is and how it develops The risk factors and causes you should watch for Key signs and symptoms Oxygen toxicity prevention And more! ___________________ Full Transcript - Read the article and view references FREE CLASS - If all you've heard are nursing school horror stories, then you need this class! Join me in this on-demand session where I dispel all those nursing school myths and show you that YES...you can thrive in nursing school without it taking over your life! Study Sesh - Change the way you study with this private podcast that includes dynamic audio formats including podquizzes, case studies and drills that help you review and test your recall of important nursing concepts on-the-go. Free yourself from your desk with Study Sesh! Clinical Success Pack - One of the best ways to fast-track your clinical learning is having the right tools. This FREE pack includes report sheets, sheets to help you plan your day, a clinical debrief form, and a patient safety cheat sheet. Med Surg Solution - Are you looking for a more effective way to learn Med Surg? Enroll in Med Surg Solution and get lessons on 57 key topics and out-of-this-world study guides. NCLEX Study Plan - Not sure how to plan your NCLEX studying or which topics to focus on? Grab this FREE guide which details strategies based on how much time you have to prepare.
In this episode of The Birth Trauma Mama Podcast, Kayleigh sits down with Rachel, a mom of two, to share her powerful and deeply layered story of navigating two very different pregnancies and births, both marked by moments of dismissal, fear, and intense advocacy.Rachel's first pregnancy shifted dramatically at 30 weeks when she developed severe high blood pressure and preeclampsia, leading to weeks of confusion, mixed messages, and ultimately an induction at 34 weeks. Her experience left deep emotional imprints, including guilt, hypervigilance, and the grief of feeling disconnected from her own birth and early postpartum moments.Years later, Rachel and her wife decided to grow their family again, a choice shaped by both longing and the fear of repeating past trauma. Her second pregnancy was medically smoother, but her birth once again challenged her sense of safety and autonomy through unheard concerns, rapid labor, and providers who dismissed her awareness of her own body.Together, Kayleigh and Rachel explore:
On an episode of The Craig and Greg Show, Greg and I discussed some toxic behaviors that can creep into your workplace and cause major discord. Two attitudes to watch out for are confidence without humility, and humility without confidence. Watch this video clip here. Check out this full Craig and Greg Show episode here. And check out my Shepherd Leadership book where I dive into this topic in greater depth at http://shepherdleadershipbook.com.
Can love be a business strategy? In this episode, we talk about how leading with love can transform your team and your bottom line. Frank Danna, a seasoned leader and marketing expert, brings his wisdom on building authentic connections in the workplace. We explore how AI can enhance, rather than replace, human creativity and the importance of creating a culture that values trust, inclusion, and vulnerability. Frank shares his personal journey from a toxic work environment to one where love and empathy drive success, offering actionable advice for leaders looking to transform their organizations. Here are some highlights: -The Power of Love in Leadership: Frank explains how love, empathy, and trust are essential to creating a successful and human-centered workplace culture. -AI and Creativity: Frank discusses how AI can free up time for leaders to be more creative and focus on what truly matters: human connections. -Building a Culture of Love: Learn the six key behaviors—Inclusion, Empathy, Vulnerability, Trust, Empowerment, and Forgiveness—that make up a culture of love in the workplace. -The Challenge of Toxicity in Leadership: Frank shares his experience of working through a toxic work culture and how a shift in leadership behavior can turn things around. -Vulnerability as a Leadership Strength: Frank highlights the importance of vulnerability in leadership and how sharing personal stories can foster real connections with your team. About the guest: Frank E. Danna is the Marketing Director at Softway and Co-Founder of Culture+, where he transforms leadership through love, empathy, and behavior-driven change. Co-author of Love as a Business Strategy and Love as a Change Strategy, Frank challenges fear-based leadership practices and champions a human-first approach. He co-created Culture Rise, a transformative leadership experience that's impacted over 6,000 leaders worldwide. Frank's expertise spans storytelling, communication strategy, and creative content, having reached 100 million viral views on Vine and co-founding GhostCodes, acquired by Softway. He's worked with brands like HBO, Twitter, and Coca-Cola, and is a sought-after speaker on culture, AI, and change. Connect with Frank: Website: www.softway.com LinkedIn: https://www.linkedin.com/in/frankdanna/ Connect with Allison: Feedspot has named Disruptive CEO Nation as one of the Top 25 CEO Podcasts on the web, and it is ranked the number 6 CEO podcast to listen to in 2025! https://podcasts.feedspot.com/ceo_podcasts/ LinkedIn: https://www.linkedin.com/in/allisonsummerschicago/ Website: https://www.disruptiveceonation.com/ #CEO #leadership #startup #founder #business #businesspodcast Learn more about your ad choices. Visit megaphone.fm/adchoices
What if the key to healing lies in forgiveness, alignment and an unexpected spiritual awakening? Dr Jane Lewis reveals how ancient Hawaiian wisdom guided her from the depths of clinical depression to a life rooted in purpose and connection. She explores the gentle power of Ho'oponopono, the importance of living in harmony with land and spirit, and why releasing old burdens can transform your wellbeing. Jane's story shows how purpose often unfolds through life's toughest lessons. If you're seeking clarity, meaning or a fresh path forward, Jane's journey offers insight, hope and a profound invitation to learn how forgiveness heals toxicity. KEY TAKEAWAY 'We underestimate the power of forgiveness. We really do. It's such a healing force. It's difficult but when you really can get to grips with it, it's such a healing force, a healing power.' ABOUT THE GUEST – DR JANE LEWIS Dr Jane Lewis is a spiritual coach, teacher and speaker who helps purpose-led women leaders reconnect with their inner power and create lasting transformation from within. Drawing on nearly 40 years' experience across the corporate, entrepreneurial and spiritual worlds, she blends ancient wisdom with modern coaching to bring clarity, alignment and deep personal growth. A lifelong explorer of the mind, body and soul, Jane works with those navigating change, seeking purpose, or ready to live more consciously. She believes real power comes from within—and that when we honour the unseen as much as the seen, true transformation becomes possible. CONNECT WITH JANE Linktree: https://linktr.ee/drjanel ABOUT THE HOST - AMY ROWLINSON Amy is a purpose and fulfilment coach, author, podcast strategist and mastermind host who empowers purpose-driven leaders to boost productivity, engagement and meaning in life and work. Through transformational conversations, Amy helps individuals overcome overwhelm and live with clarity, building living legacies along the way. WORK WITH AMY If you're interested in how purpose can help you and your business, please book a free 30 min call via https://calendly.com/amyrowlinson/call KEEP IN TOUCH WITH AMY Sign up for the weekly Friday Focus - https://www.amyrowlinson.com/subscribe-to-weekly-newsletter CONNECT WITH AMY https://linktr.ee/AmyRowlinson BUY AMY'S BOOK (Shortlisted in the 2025 Business Book Awards) * Focus on Why by Amy Rowlinson with George F. Kerr – https://amzn.eu/d/6W02HWu HOSTED BY AMY ROWLINSON DISCLAIMER The views, thoughts and opinions expressed in this podcast belong solely to the host and guest speakers. Please conduct your own due diligence. *As an Amazon Associate, Amy earns from qualifying purchases.
In episode 307, Mark & Steve respond to an all-too-common history and situation submitted by a betrayed partner. Healthy sexual intimacy after betrayal cannot simply return to what it once was; it must be rebuilt on a new foundation of authenticity and safety. Because pornography shapes the brain and rewires arousal patterns, couples often find themselves questioning what's real, what's healthy, and whether desire is rooted in connection or in old fantasy. Many partners struggle to trust, and many addicts struggle to trust themselves, creating a complex emotional landscape that must be navigated with care. This healing begins by evaluating intention and headspace—asking not what partners want to do sexually, but why they want to do it and what meaning it carries.From there, intimacy must be rebuilt through trust and transparency. Couples need to be able to talk openly about sexual preferences, fears, boundaries, and emotional needs before engaging physically. Silence or lack of objection is not consent; safety must be mutual, expressed, and explicit. Boundaries should be set outside of arousal states, and couples may need to slow down significantly—sometimes even stepping back to basics like hand-holding or non-sexual touch—while they rebuild a foundation that can hold the weight of deeper connection.Ultimately, recovering sexual intimacy after sexual toxicity is an evolving journey, not an achievement. It requires vulnerability, patience, and willingness to explore together rather than perform or comply. When couples move intentionally through this process—anchoring their sexuality in meaning, emotional presence, collaboration, and shared values—they often find themselves creating a sexual connection that is deeper and healthier than anything they experienced before recovery.For a full transcript of this podcast in article format, go to: How Do We Discover/Recover Healthy Sexual Intimacy After Sexual Toxicity and Betrayal?Learn more about Mark and Steve's revolutionary online porn/sexual addiction recovery and betrayal trauma healing program at—daretoconnectnow.comFind out more about Steve Moore at: Ascension CounselingLearn more about Mark Kastleman at: Reclaim Counseling Services
Last week, we explored the early signs of toxicity in horses. Today, we revisit a previous episode to clarify what toxicity is and how it affects your horse.Toxicity is one of the leading causes of equine disease. When the toxic load of horses exceeds what they can process, it becomes hard for their tissues to remain healthy, their organs to function as they should, and their body systems to work together to sustain good health. Today, I scratch the surface of the vast and complex topic of toxicity, giving you a little food for thought. Since this is a massive subject, I will likely revisit it and dive deeper into some of the points we cover today in future episodes.Understanding Toxicity in HorsesToxicity refers to the degree to which a substance can harm cells, tissues, organs, or entire systems. For horses, toxicity often accumulates gradually, influencing their health over time. Genetic makeup, nutrition, and environmental exposure are all factors that determine how well a horse can handle toxins. Well-nourished horses with good constitutions and minimal exposure to harmful substances are generally more resilient. Yet they can also struggle as they age, particularly between 14 and 16 years, when signs of imbalance often emerge.Early Signs of ToxicityThe initial effects of toxicity can be subtle and easy to overlook. A horse may develop a dull coat, cracked hooves, or irregular shedding patterns. Some subtler changes, such as stiffness, swelling, joint discomfort, a weakened immune system, or slow recovery from illness, could also indicate that the body struggles to handle its toxic load.Key Sources of ToxicityEnvironmental chemicals in feed, hay, and waterFertilizers, preservatives, and additivesPathogens, like bacteria, viruses, and parasitesDietary imbalancesDietary imbalances are another major factor contributing to poor equine health. Excess sugar or protein can stress the body and lead to inflammation, metabolic issues, and poor gut health, and a diet heavy in oils can disrupt the gut microbiome.AcidityAcidity in the body often results from an imbalanced diet, leading to conditions like leaky gut, systemic inflammation, and joint issues. Hormonal imbalances, such as prolonged high cortisol or insulin levels, also cause significant damage over time, contributing to tissue breakdown, laminitis, and immune dysfunction.AntioxidantsAntioxidants are crucial for combating free radicals, the unstable molecules that damage cells and DNA. Free radicals naturally occur during metabolic processes, but increase with high toxic loads. Without sufficient antioxidants to neutralize them, free radicals can accelerate aging, weaken the immune system, and cause long-term damage.The Cumulative Effect of ToxicityEven though toxins seldom cause immediate harm, they accumulate over time. A horse that has consumed feed with additives, dealt with multiple infections, or been on long-term medications may eventually show signs of toxicity. The cumulative effect often leads to nutritional deficiencies, compromised immunity, and declining health.Strategies for Reducing ToxicityEliminate unnecessary supplements and observe how the horse responds to a more natural diet. Prioritize high-quality feeds and hay with minimal additives, and avoid excessive sugar, protein, or oils, as they can disrupt metabolic health and the gut microbiome in horses. Address pathogens and infections promptly. Support detoxification with bioavailable nutrients to restore reserves and help the body manage its toxic load effectively.Final ThoughtsToxicity develops slowly. Understanding
In this episode, we dive into the dating complexities unveiled between Black men and Black women on Arlette Amuli's Pop The Balloon and Find Love. Both sides showcase hypocrisy, superficiality, and controversy; however, the women on the show seem to display these traits even more. We break down the tension, the toxicity, and the possible hidden agendas at play. Tune in as we unpack it all.
If you've been doing everything right—eating clean, exercising, and taking your supplements—but still feel tired, bloated, or off, this episode is going to change the way you think about your health. I'm joined by the incredible Kim Rogers, better known online as the “Worm Queen,” who's pulling back the curtain on the hidden world of parasites and why so many of us are unknowingly affected by them. With 20+ years in Western medicine and a powerful personal healing story through Lyme, mold, and parasite infections, Kim brings both science and passion to this eye-opening conversation. You'll learn why regular parasite cleansing can be a total game-changer for your energy, digestion, skin, and overall vitality. All of us should be doing a parasite cleanse– it's safe, effective, and an incredible way to be proactive about our health. Tune in to this episode and feel empowered to take your healing into your own hands! Kim Rogers Kim worked in western medicine for over 20 years, ran 25 healthcare colleges, was a professor, author, and holds 2 healthcare degrees– all while dealing with her own chronic illnesses. In July, 2021 Kim came across a video on Tiktok talking about parasite cleansing. She gave it a try, and because it was so successful, she saw a need to help others heal. She started her company RogersHood in December 2021 making ParaFy Parasite cleanse kit to help others cleanse their bodies of unwanted parasites, candida, heavy metals, and toxins. Her mission is to help improve testing for environmental toxins for everyone! IN THIS EPISODE How Kim Rogers became an expert in understanding parasites Why parasite testing seems to be ignored in the USA Looking at how your body responds during a parasite cleanse Why it's hard to detect parasites The actual process of parasite cleansing The benefits of a 30-day cleanse program About the ParaFy cleanse and other products from RogersHood QUOTES“The herbs that we used are specifically because they're gentle and we should all be cleansing. We should all be doing this just as a proactive way, not so much as a reactive one… It's really a sad thing, the state we're seeing chronic illness at.” “60 million people in the United States have parasites that have been tested. That's through an approved lab to give us that number.” “I'm trying to teach and show people how to be sovereign over your own health and body so that you have a little more control. Chronically ill people, one of the biggest things is that I lost control over sovereignty with my own body over an illness, and over other people around me telling me what's wrong with me, and I really want to give that control back to people.” RESOURCES MENTIONED Order my new book: The Perimenopause Revolution HERE https://peri-revolution.com/ Use code ENERGIZED and get $100 on your first CAROL Bike order https://carolbike.pxf.io/GK3LaE Use code THRIVE15 and get 15% off on your Berkeley Life order https://berkeleylife.pxf.io/Vxvdja RogersHood Website → Order the ParaFy Parasite cleanse kit HERE! Kim Rogers on Instagram RELATED EPISODES #512: How Do Our Daily Exposure to Toxins Impact Our Hormones and What We Can Do About It with Dr. Wendie Trubow #455: Environmental and Everyday Toxins That Cause Hormone Deregulation with Dr. Tom O'Bryan #654: Gut Health, Hormones, and Strength: The Real Power Trio in Perimenopause with Dr. Christine Maren #635: The Connection Between Your Gut, Inflammation, Mood, and How to Start Healing Your Microbiome with Tina Anderson
Welcome to the Oncology Brothers podcast! In this episode, we dive into the management of ROS1 fusion positive non-small cell lung cancer (NSCLC) and explore the various tyrosine kinase inhibitors (TKIs) available for this rare subset of patients. Join us along with special guest Dr. Estelamari Rodriguez, a thoracic medical oncologist from Sylvester Comprehensive Cancer Center, as we discussed: • The importance of comprehensive next-generation sequencing (NGS) in management of NSCLC. • A detailed overview of ROS1 TKIs, including crizotinib, repotrectinib, entrectinib, taletrectinib. • Common side effects associated with these agents, such as fatigue, dizziness, edema, and liver toxicity. • Clinical pearls for managing adverse events and optimizing patient care. • The significance of patient education and regular follow-ups in ensuring treatment adherence and safety. Whether you're a healthcare professional or someone interested in oncology, this episode provides valuable insights into the practical aspects of treating ROS1 fusion positive NSCLC. Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Don't forget to check out our other ToxCheck episodes, conference highlights, and treatment algorithms. Subscribe for more discussions on bridging the gap between academic research and community practice! #ROS1 #NSCLC #TKIs #Crizotinib #Repotrectinib #Entrectinib #Taletrectinib #TargetedTherapy #OncologyBrothers #LungCancer
Toxicity doesn't just hurt companies—it hemorrhages them. Learn more about your ad choices. Visit podcastchoices.com/adchoices
In today's VETgirl online veterinary continuing education podcast, we interview Dr. Sara Lister, DABT, DABVT who provides us with a critical update to increase awareness of reports of severe Apoquel® (oclacitinib) toxicosis in dogs and cats during overdose situations. Tune in to hear about the latest updates for managing oclacitinib intoxication in dogs and cats, the clinical signs, and treatment recommendations!
Overcoming Toxicity: Amy Pease's Journey to Healing and Empowerment Passionfrompain.com About the Guest(s): Amy Pease is a multifaceted professional known for her resilience and determination to overcome a traumatic upbringing to become an inspirational figure. Raised in a manipulative and abusive adoptive family, she emerged as a beacon of hope, striving to empower others facing similar challenges. Amy is a coach, mentor, keynote speaker, podcast host, and content creator on her platform, Passion from Pain. She offers courses like "Finding Strength After Toxicity," providing guidance for individuals navigating life after toxic experiences. Her upcoming book is set to launch in February 2026, which will further delve into strategies for overcoming manipulation and mental abuse. Episode Summary: In this emotionally charged episode of The Chris Voss Show, Chris Voss sits down with Amy Pease, a survivor of a challenging upbringing, to discuss her extraordinary journey from the depths of toxicity to becoming a powerhouse of empowerment and change. Amy unveils the narrative of her past—a tale of overcoming adversity to inspire others through her multifaceted career as a coach, mentor, and speaker. During this engaging episode, Amy discusses her soon-to-be-released book, "Finding Strength After Toxicity," which offers a roadmap for those overcoming toxic environments. The episode captures Amy's transformation from enduring manipulation within her adoptive family to building a successful career. She shares how she eventually overcame her struggles with depression and anxiety, regained control of her life, and now aids others through her podcast and courses. Themes of self-accountability, resilience, and personal growth are explored. Chris Voss engages with Amy in a dialogue that goes beyond her story; together, they shed light on the intricacies of coping mechanisms and strategies for liberation from toxic ties. This engaging conversation is a beacon of hope and a manual of empowerment for listeners who may find themselves in similar situations. Key Takeaways: Amy shares her journey of escaping an emotionally abusive adoptive family and the steps she took to rebuild her life independently. The importance of recognizing non-physical forms of abuse, such as manipulation and financial control, and how to plan an escape from these situations. The power of community and support in overcoming adversity, as experienced by Amy when she started anew as a single mother. How self-accountability can be a driving force in personal healing and transformation after toxic experiences. A sneak peek into Amy's upcoming book, "Finding Strength After Toxicity," which serves as a guide for people breaking free from toxic environments. Notable Quotes: "You change your situation, and all of this goes away." - A pivotal moment of realization for Amy that inspired her transformation. "I had major depression, anxiety, a lot of shame, guilt that I was dealing with… it took me 20 years to get over it." - Amy highlighting the long-term effects of her circumstances. "If I stayed with these people, it was going to kill me, and my son would end up being raised by them." - Amy on her decision to leave her manipulative family. "There's somebody walking the path or has already walked it and they can help." - Amy emphasizing the importance of shared experiences and support. "The difference between self-accountability versus self-blame… it's the difference between making it or not." - On the critical nature of accountability in personal growth.
On this episode of CA Media Podcast, I have a special guest Shamieca Reid on as we discuss a viral TikTok video; in which someone enjoys toxicity. We come together and discuss is it true that Good Men/Women considered boring or it's our illusion. Enjoy this amazing conversation and dive in to your thoughts.#camediapod #ShamiecaReid #TikTok #Viral #GloryManz #toxicity #relationship Visionary Minds Public Relations and Media is a founding supporting sponsor of the CAMedia PodcastMake sure you get your Publicity, Digital Marketing, Writing, Media Consulting Services at visionarymindsny@gmail.com where Tammy Reese is the owner.You can listen to the podcast on the following platforms:Apple Podcast: https://podcasts.apple.com/us/podcast/ca-media-podcast/id1534508960SPOTIFY: https://open.spotify.com/show/0T1qlQvvRNpBjrFz4N5X26?si=7a873afde9ed4e34You can follow the podcast atFacebook: facebook.com/CAMediaPodcastInstagram: Instagram.com/CAMediaPodcastBlue Sky:https://bsky.app/profile/camediapodcast.bsky.socialX: https://x.com/CAMediaPodcastIF you want to be on the podcast you can email the podcast at camediapodcast@gmail.com or book on linktree at linktr.ee/CAMediaPodcast and click in the booking link.
In this episode of the Oncology Brothers podcast, we are joined by esteemed hematologists Dr. Onyee Chan from Moffitt Cancer Center and Dr. Fadi Haddad from MD Anderson to discuss the management of side effects associated with tyrosine kinase inhibitors (TKIs) used in the treatment of chronic myeloid leukemia (CML). Join us as we delve into: • An overview of the different generations of TKIs, including imatinib, dasatinib, nilotinib, bosutinib, ponatinib, and asciminib. • Common class-wide toxicities such as fatigue, hypertension, gastrointestinal symptoms, and cytopenias. • Unique side effects associated with each TKI and strategies for dose optimization. • The importance of patient education and monitoring to ensure effective management of side effects. Don't forget to check out our other ToxCheck episodes on antibody drug conjugates, CAR-T therapies, and more! Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Subscribe to the Oncology Brothers for more discussions on bridging the gap between academic research and community practice in cancer care! #CML #TKI #ToxCheck #Hematology #OncologyBrothers #PrecisionMedicine
In this conversation, Dr. Sanda Moldovan and Laura Frontiero discuss the challenges many face with chronic health issues despite following a healthy lifestyle. They explore the transition from traditional to functional medicine, the importance of gut health, and the role of toxins in chronic conditions. Laura shares her methodology for healing, success stories from her clients, and emphasizes the need for a comprehensive approach to health that includes detoxification and addressing underlying issues. The conversation concludes with an invitation to Laura's upcoming masterclass aimed at helping individuals break the midlife symptom cycle and regain their health. Want to see more of The Holistic Dentistry Show? Watch our episodes on YouTube! Do you have a mouth- or body-related question for Dr. Sanda? Send her a message on Instagram! Remember, you're not healthy until your mouth is healthy. So take care of it in the most natural way. Key Takeaways: (00:00) Introduction to Health Challenges (04:44)Transitioning from Traditional to Functional Medicine (06:56) Understanding the Methodology of Healing (09:41) Success Stories and Transformations (11:51) The Role of Toxins in Chronic Conditions (12:54) The Importance of Gut Health (16:30) Detoxification: Myths and Realities (18:41) Identifying Symptoms of Toxicity (22:45) Addressing Persistent Health Issues (25:03) Upcoming Masterclass on Midlife Health (26:57) Final Thoughts and Messages of Hope Guest Info: Instagram: https://www.instagram.com/laura.frontiero/?hl=en Live Master Class: Break the Midlife Symptom Cycle! Wednesday, November 12, 2025 at 4pm PT / 7pm ET Sign Up Below! https://breakthemidlifesymptomcycle.com/registration?am_id=sanda8574 Connect With Us: AskDrSanda | YouTube BeverlyHillsDentalHealth.com | Instagram DrSandaMoldovan.com | Instagram Orasana.com | Instagram
Dr. Monty Pal and Dr. Pauline Funchain discuss the latest efforts to diagnose, prevent, and treat the series of immune-related adverse events that have emerged in the era of immunotherapy. TRANSCRIPT Dr. Monty Pal: Hello, and welcome to the ASCO Daily News Podcast. I am Monty Pal, a medical oncologist, professor and vice chair of medical oncology at the City of Hope Comprehensive Cancer Center in Los Angeles, California. Now, it is probably no surprise to this audience that immunotherapy has transformed the treatment landscape for multiple cancer types. It remains a pillar of modern oncology. Having said that, I think we have all been baffled by certain toxicities that we run into in the clinic. Today, I am delighted to be joined by Dr Pauline Funchain to discuss some of the checkpoint inhibitor toxicities that people struggle with most. And we will also touch on some side effects of immunotherapy beyond checkpoint inhibitors: CAR-T cells, bispecifics, so on and so forth. Dr Funchain is a dear friend, and she is an associate professor and associate director of cancer research training and education at the Stanford Cancer Institute. She is co-director of the Immunotherapy Toxicity Program and the Skin Cancer Genomics Program at Stanford, where she also serves as associate program director of hematology and oncology fellowship. Dr. Funchain is also the co-founder of ASPIRE, and we are going to talk about that a little bit today, the Alliance for the Support and Prevention of Immune-Related Events. FYI for listeners, if you are interested in our disclosures, they are available at the transcript of this episode. Pauline, thanks so much for joining us today. Dr. Pauline Funchain: Monty, thank you for this invitation. It is always great to talk. Dr. Monty Pal: So, for the audience, Pauline and I know each other from my days as a fellow at City of Hope. She was a resident at Harbor UCLA and a stellar resident at that. It has just been amazing to sort of see your career grow and blossom and to witness all the cool things that you are doing. ASPIRE, in particular, sort of caught my eye. So again, for listeners, this is the Alliance for the Support and Prevention of Immune-Related Events. Can you tell us a little bit briefly about the genesis of that, how that came about? Dr. Pauline Funchain: So, there was a bunch of us who were really struggling, I mean, all of us have struggled with these immune-related adverse events, these irAEs. You know, they are new disease states, and even though they look like autoimmune diseases, they tend to need a whole lot more steroid than autoimmune diseases do and they do not totally present in the same way. And in fact, you know, Triple-M, or Triple-M overlap syndrome, is a completely new irAE, a new immune state that we have never had before the advent of checkpoint inhibitor. And so a Triple-M, for those of you who are not as familiar, that is the constellation of myocarditis, myositis, and myasthenia gravis, something that never occurs as a natural autoimmune disease. So we were starting to realize that there were some major differences with these irAEs and autoimmune diseases. We could not treat them the right way. We really needed to learn more about them. And a bunch of us who had interest in this said, "Look, we really need to be all in one space to talk about what we are doing," because all of our treatments were our own little homegrown brews, and we needed to really get together and understand how to treat these things, how to diagnose them, and then learn more about them. So, Dr. Alexa Meara from Ohio State, Dr. Kerry Reynolds from Mass Gen, we put together this research consortium, brought together all of our irAE friends, got our best subspecialists together in a research consortium, which is now only about a year and a half old. And we made this research consortium, the Alliance for Support of Prevention of Immune-Related Events, and we reached out to ASCO, and ASCO was so kind to grant us a [Alliance for Support and Prevention of Immune-Related adverse Events (ASPIRE)] Community of Practice. So we met for the first time as a Community of Practice at the ASCO Annual Meeting just this past June and really got an ASCO community together to really think about how to again, diagnose, prevent, treat irAEs. Dr Monty Pal: This is interesting to me. The ASCO Community of Practice phenomenon is something that I was not super familiar with. Can you explain to our listenership what is the ASCO Community of Practice model? If you have particular interests, how do you sort of get one started? Dr Pauline Funchain: Yeah, so ASCO has an entire page on their Community of Practice. There are multiple Community of Practice groups or COPs. There are ones for Supportive Oncology and Survivorship. There is Women in Oncology. There is a group for International Medical Graduates. And there is about, I think 10 or 12 now that have a physical presence at ASCO but also a virtual presence on the ASCO Community of Practice site. So, if you were interested in any one of these, and you can see them on the ASCO Communities of Practice sites, you would ask to become a member. Once granted membership, then there is a whole webpage of postings and conversations that people can have. You can get email digests of conversations that happen on the website, and then you can anchor it with in-person participation at the Annual Meeting. Dr Monty Pal: That is awesome, and I can think of so many different foci within oncology that really sort of deserve a Community of Practice. This definitely being one of them. You know, it strikes me as being so interesting. I mean, the checkpoint inhibitors have been around for a while now. I think when you and I were in training, gosh, back then, these were just a little bit of a pipe dream, right? But having said that, I would probably say that more than half of my kidney cancer practice is either on checkpoint inhibitors, and the vast majority have been on one at some point in their past, right? With that in mind, you know, we have all treated a lot of patients with these drugs. Why is it that we still struggle to manage the toxicities? And just to take that one step further, what are some of the toxicities that, perhaps through ASPIRE or through your experience, people struggle with the most? Dr Pauline Funchain: So, I think we are still struggling with these because again, they are new disease states, right? This is what we all experienced with COVID, a brand-new virus and a brand-new syndrome. We now have 20-plus of these as irAEs. And what we have realized about them is the immune activation that happens with these is so much more than what we have seen with autoimmune diseases. So for instance, if you have a Crohn's or ulcerative colitis, you will top out at 40 to 60 milligrams of prednisone if a Crohn's flare or ulcerative colitis flare happens. But for our severe IR colitises, you know, it is at least 1 mg per kg, often goes up to 2 mg per kg. We, in some cases, have done 1 gram pulses if we are worried that somebody is going to perforate. So that was sort of like the first 5 years of treating irAE, and then now in the sort of second 5 years of treating irAE, we have realized that that is a lot of immunosuppression, and we might be able to get away with less with the newer biologics that are on board. So, we are struggling to try to get the data for some of these irAEs that we knew, we have known for a while, but to try to get newer treatments that may immunosuppress less so that you may still be able to retain that tumor response. And in fact, some of the preclinical studies suggest that some of these biologics may actually synergize with the immunotherapy and actually make the immunotherapy more effective from a tumor perspective and calm down the irAE as sort of the bystander effect. So we are still trying to optimize those. Getting up trials in the space has been very difficult. That is one of the reasons for the genesis of ASPIRE because we realized we needed to band together to have a bigger voice in that realm. Then there are other things that are brand new. So we talked about Triple-M. So Triple-M, again, with Triple-M or any myocarditis or myasthenia, I mean, there is about a 50% chance of death from irAE based on the literature. I think we are getting better at recognizing this, and so at Stanford we have some data to say that if you serially follow troponin, that maybe your outcomes are better. You can potentially lower the percentage of cases that are fatal because you can catch them early. I mean, this is all preliminary data, but again, these are all things that are evolving, and we do not all have the right answer. I mean, even the serial troponin thing, I think, is pretty controversial. And in fact, at one of our quarterly Zoom meetings that we are doing in ASPIRE in December is going to sort of flush out that controversy about serial troponin measuring and what is the best thing to use? Would you use something like abatacept or would you use ruxolitinib? Which one is better? I think there is a lot of controversy still about these things. Dr Monty Pal: You have really piqued my curiosity here because you think about the cons of treating irAEs, right? And I worry exactly about what you had mentioned, right, which is, "Gosh, what is going on with this tumor in terms of immunosuppression?" But you think about some of the newer agents, you mentioned ruxolitinib, I have heard of dasatinib, for instance, in this setting. Frankly speaking, a lot of these, as you point out, are really thought of as being also anticancer drugs. So you have really got me thinking about the potential synergy between perhaps suppressing an irAE and augmenting antitumor activity, which I think is very interesting. Am I on the right track with that? Dr Pauline Funchain: I think so, but you will find that a lot of people will not even go there because they are worried about how much immunosuppression you are going to cause. I am at heart a geneticist, but I think an immunologist will happily tell you that the immune system is very complex. There are multiple pathways, and these drugs do not all target the same immune pathways. So if we understand a little bit more about the pathways we are targeting and pick apart the pathways that are really, really tumor relevant and the other pathways that are not tumor relevant, you may be able to piece together a better marriage of tumor response and irAE control. Dr Monty Pal: Kind of on this topic, and again, leaning on your background in genetics, where are we in terms of predicting these irAEs? I mean, you would think the holy grail would be picking out a snip or something of this for it, right, that could potentially identify that patient who is going to get Triple-M or, you know, at the very least a significant high-grade irAE event. Are we anywhere closer to that in 2025? Dr Pauline Funchain: There have been data published. There have been some big GWAS studies. All of the effect sizes are pretty small. So there are some prediction algorithms, but none of them are clinically useful. And I think when you look at the odds ratios, they will increase risk by maybe 20%. I think one of the things that we found in a very small series and supported anecdotally is something as easy as family history of autoimmune disease is probably more predictive at this point than any of those types of markers. I think we will get there, but we are not anywhere near where we would like to be. Things like TMB also, actually, there is some good data about higher TMB, higher risk of irAE too. Dr Monty Pal: Interesting. I see all this data coming through, IL-8 polymorphisms, etc. And I just wondered if any of that was ready for prime time. But I mean, this is a good message for the practicing clinician. Sounds like we are not quite there yet. And I could probably keep you on for another entire podcast to talk about this topic, but let us see if we can at least skim the surface. I never thought I would see the day when BiTEs and CAR-Ts were entering into my kidney cancer practice, but in fact, it is really become central to a lot of our clinical trials in RCC these days. I would be lying if I did not say that I was not struggling with the toxicities and so forth associated with these drugs. Can you give us a quick primer, maybe just good resources that people can go to for managing toxicity with BiTEs and with CAR and with some of these novel therapeutic modalities that we are using in the oncology clinics? Dr Pauline Funchain: I know there is a recently published toxicity manual for BiTEs in hematologic malignancies, I think it was in Blood. CAR-T is covered in many irAE guidelines. So ASCO guidelines actually has a CAR-T [cell therapy guideline], and I would be remiss not to point out that actually ASCO has a, I am a little biased, but a wonderful guideline on irAE that is actually being updated as we speak. We are hoping for publication next year. I find the format of that, there are many guidelines out there, actually. There is ASCO, SITC, ESMO has a guideline for irAE, but I find the formatting of the ASCO guideline to be much easier to flip through during clinic, just because of the visual format of the tables. But that is going to be updated next year. And with CAR-T, there is now multiple publications also in terms of guidelines. But what I will say about bispecifics and CAR-T, so they have very similar toxicities in terms of the cytokine release and also with the ICANS, so the neurotoxicity. But what we have been finding that is really interesting with BiTEs and CAR-T, and actually even with TIL, cytokine release is very similar to some of the IL-2 toxicities but not identical that we see with TIL treatment. But now we are starting to see overlap. So patients who have been treated with immunotherapy and then go on to get a bispecific or then go on to get TIL, so I have seen some colitises that have occurred after the fact. Some of the newer CAR-Ts without checkpoint have been causing some really interesting, probably not in a good way, but interesting biologically, colitises that are really refractory. So we are starting to see some overlap, and again, I think this field is just evolving constantly. Dr Monty Pal: Yeah, no, I almost think I need to go back to that fellowship that you and I did together 20 years ago and, you know, and see if I could repeat some coursework on CAR-T management. You know, Pauline, I could probably keep you on the horn for hours, but this has just been terrific. Thank you so much for sharing all of your insights with us today on the ASCO Daily News Podcast. Dr Pauline Funchain: Thank you for the invitation. It was wonderful to talk about this, and it was wonderful to catch up a little bit, Monty. Dr Monty Pal: Same here, same here. And thanks to our listeners too. If you value the insights you heard today on the ASCO Daily News Podcast, please rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speakers: Dr. Monty Pal @montypal Dr. Pauline Funchain @FunchainMD Follow ASCO on social media: @ASCO on Twitter ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. Monty Pal: Speakers' Bureau: MJH Life Sciences, IntrisiQ, Peerview Research Funding (Inst.): Exelixis, Merck, Osel, Genentech, Crispr Therapeutics, Adicet Bio, ArsenalBio, Xencor, Miyarsian Pharmaceutical Travel, Accommodations, Expenses: Crispr Therapeutics, Ipsen, Exelixis Dr. Pauline Funchain: Consulting or Advisory Role: Merck, Replimune, Sanofi/Regeneron, Immunocore, Tempus Research Funding (Inst.): Pfizer, Bristol-Myers Squibb, IDEAYA Biosciences, Linnaeus Therapeutics Travel, Accommodations, Expenses: Merck
Fluoropyrimidines such as 5-fluorouracil (5-FU) and capecitabine remain cornerstone chemotherapies in oncology. However, for patients with certain DPYD gene variants, these commonly used drugs can cause life-threatening toxicities due to impaired metabolism of the active compounds. In this episode of the Precision Medicine Pharmacist Podcast, host Melissa Smith, PharmD, explores how DPYD genotyping is transforming oncology care by helping clinicians identify patients at risk before toxicity occurs. Joined by Karen Merritt, an advocate for universal DPD testing and leader with the Test4DPD initiative, the discussion sheds light on how pharmacogenomics is shaping safer, more personalized cancer treatment. Together, they explore current evidence, new FDA updates, and implementation frameworks that empower pharmacists and oncology teams to prevent preventable harm through precision medicine.
On our perpetual quest for bigger, better, faster, wealthier, and stronger, we're led to believe that more is the answer – more gadgets, advanced technology, connections, resources, money, entertainment, etc. But what if there was a case to be made the answer to fulfillment is not in more but in less? My guest today, Dewyane Noel, makes that case. We talk about why less is more, how to reduce noise, chaos, and distraction in the modern world, the value of a hard day's work, what we can learn about human behavior through good horsemanship, and why good men ride good horses. SHOW HIGHLIGHTS 00:00 – Working Together as Men 04:21 – Teaching the Next Generation of Horsemen 07:49 – "He Rode Good Horses" and Life Lessons 09:16 – A Man's Epitaph and Legacy 09:59 – The Purpose Behind Becoming a Better Man 13:09 – Hitting Rock Bottom and Choosing Change 17:19 – Guarding Peace and Avoiding Old Patterns 19:53 – Living Off the Grid and Finding Rest 24:38 – Setting Boundaries and Protecting Privacy 25:39 – Why Dwayne Began Sharing His Message 27:47 – The Best Advice: Just Chill 30:55 – Needing Less vs. Always Wanting More 35:38 – Filtering Needs vs. Wants 42:23 – The Easiest Person to Lie to Is Yourself 43:10 – How a Man Learns to Like Himself 48:51 – Weakness, Horses, and Assertiveness 51:25 – Leadership, Trust, and the Alpha Role 57:24 – Teaching Responsibility Before Autonomy 01:04:10 – Redefining Manhood and Discipline 01:07:30 – Fatherhood, Boundaries, and "Toxicity" 01:12:29 – The Benevolent Alpha in Marriage 01:15:34 – Growth, Maturity, and Becoming a Better Man Battle Planners: Pick yours up today! Order Ryan's new book, The Masculinity Manifesto. For more information on the Iron Council brotherhood. Want maximum health, wealth, relationships, and abundance in your life? Sign up for our free course, 30 Days to Battle Ready
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