The ability of a chemical to cause damage to life
POPULARITY
Categories
94 episodes with Toxicity
23 episodes with Toxicity
20 episodes with Toxicity
16 episodes with Toxicity
23 episodes with Toxicity
19 episodes with Toxicity
11 episodes with Toxicity
13 episodes with Toxicity
12 episodes with Toxicity
9 episodes with Toxicity
8 episodes with Toxicity
16 episodes with Toxicity
20 episodes with Toxicity
12 episodes with Toxicity
7 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
9 episodes with Toxicity
8 episodes with Toxicity
10 episodes with Toxicity
6 episodes with Toxicity
10 episodes with Toxicity
9 episodes with Toxicity
9 episodes with Toxicity
8 episodes with Toxicity
8 episodes with Toxicity
9 episodes with Toxicity
9 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
6 episodes with Toxicity
11 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
4 episodes with Toxicity
7 episodes with Toxicity
5 episodes with Toxicity
4 episodes with Toxicity
5 episodes with Toxicity
7 episodes with Toxicity
11 episodes with Toxicity
4 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
4 episodes with Toxicity
8 episodes with Toxicity
3 episodes with Toxicity
6 episodes with Toxicity
6 episodes with Toxicity
7 episodes with Toxicity
12 episodes with Toxicity
9 episodes with Toxicity
8 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
5 episodes with Toxicity
11 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
6 episodes with Toxicity
8 episodes with Toxicity
4 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
11 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
8 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
5 episodes with Toxicity
2 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
10 episodes with Toxicity
3 episodes with Toxicity
5 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
4 episodes with Toxicity
5 episodes with Toxicity
4 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
6 episodes with Toxicity
10 episodes with Toxicity
2 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
9 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
2 episodes with Toxicity
4 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
8 episodes with Toxicity
2 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
4 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
3 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
10 episodes with Toxicity
2 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
2 episodes with Toxicity
What dose and mode of ingestion of B12 do you recommend for an active 78-year-old husband and wife?If ubiquinol is more bioavailable than CoQ10, what about other supplements with respect to bioavailability?Does proline help ligaments?What are your thoughts on smart watches and EMF exposure?
We're living longer thanks to medical advancesStudy: Does cannabis use increase the risk of diabetes?What dose of selenium and iodine should I take?What do you suggest for people who have carpal tunnel syndrome? I would like to avoid surgeryWhat do you think of the claims made for EDTA? Are there benefits?I have the beginnings of macular degeneration. Is taking the AREDs supplement helpful?
We discuss propofol infusion syndrome (PRIS) and propylene glycol toxicity from lorazepam infusions, with medical toxicologist Dr. Jerry Snow, director of the toxicology fellowship at Banner University Medical Center in Phoenix. Learn more at the Intensive Care Academy! Takeaway lessons
Featuring an interview with Dr Neel Pasricha, including the following topics: Anatomy and physiology of the cornea; intersection of ophthalmology and oncology for patients receiving antibody-drug conjugates (ADCs) (0:00) Association of corneal toxicities with ADCs (4:56) Dose and schedule modifications to mitigate ocular toxicities associated with belantamab mafodotin and other ADCs (9:02) Spectrum and severity of corneal toxicities associated with datopotamab deruxtecan (14:44) Role of optometrists and ophthalmologists in screening for and management of ocular toxicities (17:55) Other ocular toxicities associated with cancer therapies (24:26) Prevention and management of corneal toxicity (33:58) Preexisting ophthalmic conditions as potential risk factors for development of ocular toxicities with ADCs (43:39) General clinical pearls on the management of ocular toxicities with cancer therapies (48:04) CME information and select publications
Dr. Ravi Kamepalli made a startling realization that changed everything: bacteria aren't the enemy. As both an infectious disease specialist and wound care physician, he witnessed firsthand how traditional medicine's war on microbes was failing patients catastrophically. In this profound conversation, he unveils his revolutionary "disease triangles" framework that connects our immune system, lipid metabolism, and microbiome in ways that transform how we understand healing.The statistics he shares will shock you: diabetic foot amputations have a higher five-year mortality rate than breast cancer. While diabetes costs healthcare systems $237 billion annually compared to cancer's $80 billion, we're attacking symptoms instead of root causes. Dr. Kamepalli explains his concept of "energy toxicity" - how excess stored energy triggers inflammatory cascades that turn our own immune systems against us.Through his personal journey of losing 50 pounds and dramatically reducing his LP(a) levels, he demonstrates that supposedly "genetic" markers are actually nutritionally modifiable. His approach integrates metabolic interventions with wound care, using continuous glucose monitoring, food logging, and remote patient tracking to address the underlying metabolic dysfunction that prevents healing.This isn't just about wound care - it's about reimagining medicine itself. Dr. Kamepalli advocates for moving beyond "mass medicine mindset" toward personalized, n-of-one healthcare that empowers patients with tools, tracking, and understanding rather than simply prescribing interventions. His vision extends from revolutionizing American healthcare to building sustainable systems in rural India.BIG IDEA"We cannot kill bacteria and keep the humans alive - we need to learn how to survive together, and that survival depends on fixing our metabolic dysfunction, not declaring war on microbes."Dr. Ravi Kamepalli Contact InfoWebsite: https://nobadbugs.com/Social Media: @WoundPhysicianWebsite: ColigoMed.comSociety for Metabolic Health Practitioners SMHP.orgSend Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Stay Off My Operating Table on X: Dr. Ovadia: @iFixHearts Jack Heald: @JackHeald5 Learn more: Stay Off My Operating Table on Amazon Take Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart Health Jack Heald's website: CultYourBrand.com Theme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.
Dr Neel Pasricha from the University of California, San Franciso, reviews corneal and other ophthalmic toxicities associated with antibody-drug conjugates and other cancer therapies and strategies for their prevention and management. CME information and select publications here.
Dr Neel Pasricha from the University of California, San Franciso, reviews corneal and other ophthalmic toxicities associated with antibody-drug conjugates and other cancer therapies and strategies for their prevention and management. CME information and select publications here.
Today we're doing a deep dive into RHOC, where Tamara brought of the ancient drama of Naked Wasted at a lie decector party. We went back and refreshed our memories by watching Naked Wasted (Season 4, Episode 8 if you'd like to do the same) and we have some THOUGHTS! After we explore the toxicity of RHOC we'll dip our toes into the palette cleanser of Real Housewives of Miami and recap our thoughts on their trip to Seville. Plus: Unknown Number, why Bravo is more enjoyable now that we're sober, and our personal experiences with ADHD and OCD minds. Are you craving community in sobriety? Join us in The Sober Mom Life Cafe! You'll get access to 4 weekly peer support meetings, the exclusive Cafe social feed, our monthly book club, the chance to share your story on The Real Sober Moms, and more! Get one week free at this link! The Sober Shift is now available for pre-order! Pre-order now for three free mocktail recipes and access to my pre-order launch Zoom in October. Plus, take a look at my events calendar for a book tour stop near you. I would LOVE to meet you and thank you for being a part of this incredible community! We have two spots open for The Sober Mom Life retreat Oct 23-26th in Scottsdale, AZ! Join us for an incredible sober getaway!https://www.instagram.com/thesobermomlife/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Featuring perspectives from Prof Rebecca A Dent, Dr Hans Lee, Dr Neel Pasricha and Dr Tiffany A Richards, including the following topics: Introduction: The Patient Experience (0:00) Managing Ocular Toxicities Associated with Antibody-Drug Conjugates and Other Cancer Therapies — Dr Pasricha (10:28) Ocular Toxicities in Multiple Myeloma (45:33) Ocular Toxicities in Breast Cancer (50:34) CME information and select publications
Prof Rebecca A Dent from National Cancer Centre Singapore, Dr Hans Lee from Sara Cannon Research Institute in Nashville, Tennessee, Dr Neel Pasricha from the University of California, San Francisco, and Dr Tiffany A Richards from The University of Texas MD Anderson Cancer Center in Houston, discuss strategies to manage ocular toxicities associated with antibody-drug conjugates and other cancer therapies. CME information and select publications here.
Prof Rebecca A Dent from National Cancer Centre Singapore, Dr Hans Lee from Sara Cannon Research Institute in Nashville, Tennessee, Dr Neel Pasricha from the University of California, San Francisco, and Dr Tiffany A Richards from The University of Texas MD Anderson Cancer Center in Houston, discuss strategies to manage ocular toxicities associated with antibody-drug conjugates and other cancer therapies. CME information and select publications here.
What do the acronyms ConVENTID, VENTID and ASS all have in common? Well, have a listen and find out as the boys continue their journey down Highway O2 while avoiding the pitfalls of oxygen Toxicity. Have A Listen!!
The Dad Edge Podcast (formerly The Good Dad Project Podcast)
In this special father-son episode of the Dad Edge Podcast, I sit down with my 19-year-old son, Ethan Hagner, to talk about the ever-evolving world of modern dating, masculinity, and what respect looks like in today's culture. From Snapchat and Bitmoji “vibes” to the dangers of digital footprints, Ethan pulls back the curtain on what Gen Z is really experiencing when it comes to relationships, identity, and self-worth. We get raw and real about breakups, social media drama, posting for “social therapy,” and what red flags look like in 2025. But the conversation goes much deeper than dating. Ethan opens up about his personal growth, past mistakes, and what he'd tell his 16-year-old self—and future daughter—about how to protect your integrity in the world of online relationships and viral opinions. This is a must-listen for any dad raising teens or preteens. It's funny, eye-opening, brutally honest, and packed with generational wisdom from both sides of the table. TIMELINE SUMMARY [0:00] - Welcome to the Dad Edge mission [1:04] - How dating has changed since “back in the day” [2:38] - Meet Ethan Hagner: college, EMT prep, and dad banter [3:58] - Inside the Dad Edge studio & sponsor shoutout (First Form) [5:36] - Ignition + Formula 1 explained: post-workout must-haves [8:08] - Pre-order info: The Pursuit of Legendary Fatherhood [9:11] - How 19-year-olds actually meet people now (Snapchat!) [10:20] - Snapchat's “Quick Add” and Bitmoji-deep dating decisions [14:04] - Dating vs. passing notes in the 90s, how we used to ask friends to “talk to her for me” [16:06] - Red flags on social profiles: vaping, weed, or weird vibes [20:30] - Toxicity, trust, and “the feeling you just can't explain” [24:30] - Social media therapy: breakups that go viral [27:03] - Digital drama and public TikTok crying [30:27] - The real meaning of “game” for Gen Z (hint: not confidence) [32:02] - Confidence vs. bravado: what women really respond to [34:09] - What healthy confidence looks like in teens [35:30] - Are ICks ruining relationships before they start? [39:22] - Ego, lifting, and growing up with the wrong friend group [41:13] - Self-awareness: from wife beater tanks to regretful beliefs [42:35] - Advice Ethan would give his future 16-year-old daughter [43:10] - Digital safety, values, and protecting your future [46:40] - Larry's top two dating lessons for his younger self [47:40] - Regret from not approaching vs. regret from rejection [48:16] - When you strike out, you're still winning [51:11] - Protecting your reputation on social media [52:22] - First Form Dad of the Month: Ty Twizzler's inspiring story 5 KEY TAKEAWAYS 1. Snapchat Changed Dating Forever For Gen Z, Snapchat is the new hallway, lunch table, and dating app combined. But what happens there leaves a permanent digital trail—so teach your kids to tread carefully. 2. Confidence Wins—Ego Repels Bravado might grab attention, but real confidence comes from knowing who you are and not bending for validation. It's quiet, steady, and deeply attractive. 3. Respect Is Never Outdated Whether it's how you treat a teacher, a girlfriend, or yourself, respect is foundational. True character shows when no one's watching—or when everyone's watching online. 4. Your Digital Footprint Never Goes Away Posting relationship drama on TikTok or Snapchat may feel therapeutic in the moment, but it can damage reputations, create enemies, and attract the wrong kind of attention. 5. You're Not Too Young to Lead Ethan may be 19, but his mindset about dating, identity, and future family is already grounded in wisdom. His generation needs more examples like this—and so do ours. LINKS & RESOURCES
This ain't clickbait. This is me, Marie Shadows, talking straight from the heart about wrestling, music, and life without Twitter breathing down my neck.Inside this episode:
What if the very foundation of America was built on a system that was never meant to serve us all? And what if reclaiming something as simple and as profound as our intuition could be the key to creating a more just and loving future? In this episode of HEAL with Kelly Podcast, I sit down with scholar, advocate, and bestselling author Anna Malaika Tubbs to explore the roots of American patriarchy. Drawing from her recent book Erased: What American Patriarchy Has Hidden from Us and her celebrated debut The Three Mothers, Anna reveals how patriarchy was intentionally written into law, how it continues to shape institutions like healthcare and education, and why reclaiming women's intuition is one of the most radical steps we can take toward change. We explore the intentional design of patriarchy in America's laws, and why recognizing that history is often written by those in power is essential to collective healing. Anna highlights the stories of courageous women who have been erased, yet whose contributions have powerfully shaped our nation's evolution. Anna also shares insights on partnership, motherhood, and the ways our relationships and communities can model new ways of sharing power…the path to true democracy. This conversation is both eye-opening and empowering, offering a reminder that because these systems were built, we have the power to build something different. Key Moments You'll Love:
In this conversation, Dr. Jockers sits down with Dr. Paul Savage to explore the hidden roots of chronic inflammation. You'll hear how toxins are the driving force behind today's rise in disease and how plasma exchange therapy is offering people a way to lower their toxic load, calm inflammation, and regain vitality. You'll find out why the usual detox methods like sauna, fasting, and binders don't always cut it anymore. Dr. Savage explains how toxins disrupt nutrient absorption, shut down key pathways, and even damage your body's natural detox systems, making advanced approaches like plasma exchange more necessary than ever. You'll also discover how plasma exchange works, why it's safer and more effective than many other methods, and the kind of real results patients are seeing. From stronger immune systems to clearer thinking and more energy, this episode shows how reducing toxins at the source can change everything. In This Episode: 00:00 Introduction to Plasma Exchange 00:17 Podcast Introduction and Guest Overview 00:46 Understanding Toxins and Detox Strategies 01:48 Introduction to Dr. Paul Savage and MD Lifespan 04:59 Interview with Dr. Paul Savage Begins 05:17 Hidden Sources of Chronic Inflammation 06:48 The Role of Toxins in Chronic Inflammation 08:54 Therapeutic Plasma Exchange Explained 15:32 Functional Medicine Approach to Plasma Exchange 22:55 Patient Selection Criteria 26:23 The Plasma Exchange Procedure 30:54 Clinician Collaboration and Expansion 35:01 Future of Functional and Longevity Medicine 39:43 Final Thoughts and Recommendations Looking for a clean, nutrient-packed snack? Paleo Valley's Grass-Fed Meat Sticks are free from sugar, additives, and preservatives—just pure protein and healthy fats to keep cravings in check and support muscle and immune health. They come in delicious flavors like Original, Garlic Summer Sausage, and Teriyaki, and they're even kid-approved. Try them today and get 15% off your order at paleovalley.com/jockers. Think heartburn comes from too much stomach acid? Think again. Most digestive issues actually stem from too little stomach acid. That's why I recommend Just Thrive Digestive Bitters—they naturally stimulate stomach acid, bile, and enzymes to improve digestion, reduce bloating, and boost nutrient absorption.Save 20% off your order with code JOCKERS at justthrivehealth.com. Support your skin from the inside out with Clearstem, the acne brand that connects internal and external skincare without pore-clogging ingredients. Pair their best-selling Mind Body Skin hormonal acne supplement with Clearstem's clinically effective topicals for results that last. Get 15% off your order today at clearstem.com/drjockers using code DRJOCKERS at checkout. "99.9% of chronic inflammation is driven by toxins. Plasma exchange is a game-changer in detoxing your system." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get 15% off Paleovalley: paleovalley.com/jockers – Use code JOCKERS Save 20% on Just Thrive: justthrivehealth.com – Use code JOCKERS Get 15% off: https://clearstem.com/drjockers - Use code DRJOCKERS Connect with Dr. Paul Savage: Website: https://mdlifespan.com/ Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
Effective management of adverse events and addressing barriers to care are critical to optimizing outcomes and maintaining quality of life for patients receiving CDK4/6 inhibitors. In this episode, CANCER BUZZ speaks with Julia Lea Ziegengeist, PharmD, BCOP, clinical pharmacist coordinator in solid tumor oncology at Atrium Health Levine Cancer Institute about proactive, team-based strategies to identify, monitor, and manage treatment-related toxicities in patients with early-stage and metastatic HR-positive, HER2-negative breast cancer. Dr. Ziegengeist sheds light on the patient journey, the roles of various multidisciplinary care team members, and useful resources for language and literacy barriers. “I think the biggest thing that is specific to CDK4/6 inhibitors is... eligibility criteria and when we're using the drugs in what setting, having those monitoring protocols and getting that multidisciplinary collaboration is really key.” – Julia Lea Ziegengeist, PharmD, BCOP Julia Lea Ziegengeist, PharmD, BCOP Clinical Pharmacist Coordinator, Solid Tumor Oncology Levine Cancer Institute Atrium Health Charlotte, NC Resources: ACCC Resource: CDK4/6 Inhibitors Management ACCC CDK4/6 Inhibitors Infographic
Carli Davis is a functional sports dietitian who helps active women fuel smarter, prevent burnout (aka REDs), and support hormone health—without fad diets or pseudoscience. A lifelong runner and former collegiate athlete, she's especially passionate about working with endurance athletes, but enjoys helping anyone who values their health and wants to feel their best. Carli began her career in clinical nutrition in 2017, specializing in nutrition support in the ICU and for those undergoing bone marrow transplants. In 2021, she transitioned to preventive health and launched her own private practice in 2024 after relocating to Austin. Her approach is deeply integrative and personalized—combining functional lab testing with root-cause exploration to go beyond the “everything looks normal” response when the body is clearly asking for more. She's on a mission to help women avoid the pitfalls of underfueling and return to a thriving state—where performance, hormone balance, and day-to-day energy align. Carli also values collaboration and often partners with other providers, such as physicians and therapists, to ensure her clients receive well-rounded support. You can connect with Carli or book a free discovery call at https://www.carlirunnutrition.com/ , or check out her popular Meal Planning Guide at https://carli-run-nutrition.kit.com/products/meal-planning-made-easy. In this episode we chat about: Toxicity of running to lose weight Dieting is crushing your performance goals What is RED-s and why you should know about it Why you need to strive to be fertile (even if you don't want a baby) Why carbs are so important Your toxic job is literally killing you Its okay to not train for a race Moving your body shouldn't be your ONLY coping mechanism Why intermittent fasting is trashing your performance Learn more about working with me Shop my masterclasses (learn more in 60-90 minutes than years of dr appointments) Follow me on IG Follow Carli on IG
For freelancers and creatives, surrounding yourself with the right people is critical to staying motivated and inspired. Today's episode dives into the "bad apple effect," how negative influences impact your life and work, and how to remove them to create space for positivity and productivity.OFFICIAL WEBSITE: https://www.filmproproductivity.com/TWITTER: https://twitter.com/FilmProProdPodFACEBOOK: https://www.facebook.com/filmproproductivityCONTACT: https://www.filmproproductivity.com/contactINDIE FILM HUSTLE: https://indiefilmhustle.com/ifh-podcast-network-filmmaking-and-screenwriting/YOUTUBE: https://www.youtube.com/channel/UCqo0Zld2Lm2lJDpDh3GsuZgQUOTES:You are the average of the five people you spend the most time with. Jim RohnSurround yourself with people who lift you higher. Oprah WinfreyDon't let negative and toxic people rent space in your head. Raise the rent and kick them out. Robert TewA rotten apple quickly infects its neighbour. Benjamin FranklinTHIS EPISODE IS SPONSORED BY: -----------------------------------------------------------Please check out my friends shows:FILM FIGHTS WITH FRIENDS PODCASTTHE FILMMAKERS PODCASTTHE HORROR CUTWILDE WORLD-----------------------------------------------------------Thanks:A Himitsu Music: Adventures by A HimitsuCommons — Attribution 3.0 Unported— CC BY 3.0http://creativecommons.org/licenses/b...Music released by Argofox https://www.youtu.be/8BXNwnxaVQEMusic provided by Audio Library https://www.youtu.be/MkNeIUgNPQ8 –––Contact the artist: x.jonaz@gmail.comhttps://www.facebook.com/ahimitsuhttps://www.twitter.com/ahimitsu1https://www.youtube.com/channel/UCgFwu-j5-xNJml2FtTrrB3A
Toxicity is a culture killer. It can be hard to recognize and even harder to change. This happens because people struggle to recognize negative habits in others and themselves. Cultures are built, not found, whether you know it or not. A toxic culture will ruin the professional experience of its people and you have to recognize and address it as soon as possible. The problem is that most people are uncomfortable addressing it because it's a “people thing”. You have to understand others' perspective and be willing to have tough conversations. I have a way of looking at toxicity that is more personal and direct than the average culture advice. Take note of the steps in the process and learn to take them with caution and compassion. Have a great rest of your week.
In this episode of The Collective Perspective, we unpack the hidden cost of holding grudges — and the life-changing freedom that forgiveness brings. Grudges poison our minds, our bodies, and our relationships, keeping us stuck in cycles of negativity and blame. Forgiveness, on the other hand, isn't weakness — it's one of the strongest choices you can make.We talk about how grudges trap us in toxic thinking, how forgiveness shifts our mindset to growth, and how this process is especially powerful for those healing from trauma and PTSD.Are you just going to sit there and dwell on what's wrong — or take back your power, forgive, and move forward?Join Jeff and Travis for practical ways to let go, think positive, and break free from the weight that's holding you down. Listen, share, and take on the challenge: Who do you need to forgive — and how will you start today?#forgiveness #grudges #mentalhealth #positivemindset #healing #ptsdrecovery #emotionalhealth #mindsetshift #personaldevelopment #selfgrowth Chapters (00:00:00) - Introduction: What Makes America Stronger(00:00:26) - Welcome Back: Meet the Hosts(00:00:38) - The Toxicity of Grudges(00:01:30) - The Power of Forgiveness(00:03:30) - Ego and Grudges in Politics(00:06:01) - Personal Stories of Grudges(00:16:28) - Forgiveness vs. Reconciliation(00:18:01) - Practical Ways to Forgive(00:23:05) - Road Rage and Forgiveness(00:24:13) - Conclusion: Final Thoughts and Farewell
Dioxin-like compounds can alter how white blood cells develop and do so in ways that current risk assessment methods fail to predict, according to a study from the Michigan State University Superfund Research Program Center.
Why Minnesota Twins players feel uncomfortable; How did the Twins get here from two years ago; Why the Twins hitting staff faces challenges; Are the Twins going toxic; The dynamics of young players leading the Twins; Plus other Twins talkers with Trevor Plouffe See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Why Minnesota Twins players feel uncomfortable; How did the Twins get here from two years ago; Why the Twins hitting staff faces challenges; Are the Twins going toxic; The dynamics of young players leading the Twins; Plus other Twins talkers with Trevor Plouffe See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Women's health is complicated, isn't it? Between stress, hormones, and all the changes that come with midlife, it can feel like we're constantly trying to put puzzle pieces together without seeing the full picture. That's why I loved sitting down with Dr. Margaret Christensen to talk about what's really going on beneath the surface. She's sharing a perspective on health, intimacy, and connection that every woman deserves to hear. Dr. Margaret walked this journey herself. After facing serious health challenges from toxic mold exposure, she shifted from being a traditional OB-GYN to a leader in functional medicine. Now she helps women uncover the root causes of what's draining their energy, throwing off their hormones, and leaving them feeling disconnected. In our conversation, she opens up about midlife changes, hormone therapy, and how we can reclaim both our vitality and our joy. What really struck me was how she talks about sexuality and connection, not as something to be hidden or ignored, but as a powerful force for healing. We cover everything from navigating menopause to rekindling intimacy to why relationships are so key for our health. If you've ever felt like you're just pushing through midlife instead of thriving in it, this is a conversation you won't want to miss. And if you're ready for a little extra support, I'd love to have you in my 10-day Breeze Through Menopause masterclass, just $17 at dranna.com/breeze. Key Timestamps: [00:00:00] Introduction. [00:03:42] Sacred sexuality discussion. [00:06:03] Spirituality and health connection. [00:08:14] Clinical experience vs. published studies. [00:10:18] Chronic stress and hormonal disruption. [00:14:11] Autoimmunity increase post-COVID. [00:17:51] Post-midlife love story. [00:19:32] Sacred sexuality and body appreciation. [00:23:27] Power of creativity in aging. [00:24:57] Hormone replacement therapy considerations. [00:30:14] Hormonal rewiring during menopause. [00:33:08] Pressure cooker of our lives. [00:35:47] Weight gain and biotoxins. Memorable Quotes: "Sacred sexuality is really honoring our God-given gifts and our bodies." [00:20:54] – Dr. Margaret Christensen "We are energetic beings, we are energetic bodies, everything is made of energy." [00:34:07] – Dr. Margaret Christensen Links Mentioned: 10-Day Masterclass: https://dranna.com/breeze GLP Herbal: http://dranna.com/glpherbal Connect with Dr. Margaret Christensen: Website: https://margaretchristensenmd.com/ Instagram: https://www.instagram.com/drmargaretchristensen/ & https://www.instagram.com/carpathiahealth/ Facebook: https://www.facebook.com/CarpathiaCollaborative Connect with Dr. Anna Cabeca: Website: https://drannacabeca.com/pages/show Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca Produced by Evolved Podcasting: www.evolvedpodcasting.com
An increasing number of case reports have linked turmeric extract supplements to liver injury.
Toxicity is something I've been focusing on more than ever—because it's everywhere. From the water we drink to the air we breathe, the buildings we live and work in, even the everyday products we use—environmental toxins are silently impacting our health at the deepest levels.That's why I'm excited to bring you this powerful conversation with Dr. Kelly McCann—an integrative physician and true pioneer in environmental medicine. Dr. McCann has called environmental toxins the “tsunami” behind today's chronic disease epidemic, and in this episode, she breaks down exactly why.Whether you've been told you're "too sensitive" to chemicals or you've been struggling with chronic symptoms that no one can seem to explain, this episode is a must-listen.Dr. McCann has helped thousands of patients navigate complex medical issues—chronic illness, autoimmune disease, gut dysfunction, hormone imbalances, and more—through compassionate, root-cause-focused care. Her approach blends deep clinical expertise with a calm, healing presence that's helped so many on their path to wellness.In this episode, we explore:Environmental toxicity at the core of the chronic disease crisis & why environmental medicine is the most overlooked component in the functional health arena.The difference between persistent vs non-persistent toxins—and why total load mattersMast Cell Activation Syndrome (MCAS), multiple chemical sensitivity & hidden triggersHow to effectively detox your home and your bodyThe truth about sweating: passive vs active detox, sauna protocols, and what actually worksDr. McCann's clinical insights on binders and supporting sensitive patientsThe crucial connection between antioxidant enzymes and longevityHow environmental toxins interact with gene variants—leading to thicker blood, strokes, and heart attacksConnect with Dr. Kelly McCann:
Send us a text
This week on Really Feminine, we're talking about how to stay gracious and poised even when life gets messy. From practicing proper technology etiquette in a world that's always online, to our Tea Time chats about the sting of not being invited to a family wedding, handling an overbearing grandmother with a newborn, and learning how to level your expectations when toxic people keep letting you down. Carla and Michelle bring practical wisdom with a feminine touch to help you navigate relationships with grace and strength.To support the mission of Bochy's Org.- Bochys.org (https://bochys.org) • To register for The Experience England click here- Experience England (https://www.carlashellis.com/england) • To explore more about Carla click here- CarlaShellis.com (https://carlashellis.com)#FeminineGrace #RelationshipEtiquette #ReallyFeminineSupport the show
Ready to transform your HR operations?Download Deel's free AI-powered HR guide and discover how to streamline processes, stay compliant, and scale globally with ease: https://shorturl.at/Y1ySBWhy do toxic workplaces thrive, and how can leaders turn them around? In this HR L&D Podcast episode, we're sitting down with Dr Mary-Clare Race, a workplace psychologist and leadership expert, to uncover the psychology of toxic cultures and the strategies that transform them into thriving, inclusive environments.From her PhD research to leading DE&I initiatives for companies like Barclays, GSK, and Unilever, Dr Race explains why harmful behaviors persist, how to rebuild belonging, and why empathy, resilience, and self-awareness are the hallmarks of great leadership. She shares practical ways to hold leaders accountable, strengthen workplace connection, and use AI as a tool to support human-centered coaching.Whether you're in HR or lead a team, this conversation delivers actionable insights for creating healthier, more productive workplaces.Dr Mary-Clare Race's LinkedIn: https://www.linkedin.com/in/dr-mary-clare-race-b59a602/Nick Day's LinkedIn: https://www.linkedin.com/in/nickday/Find your ideal candidate with our job vacancy system: https://jgarecruitment.ck.page/919cf6b9eaSign up to the HR L&D Newsletter - https://jgarecruitment.ck.page/23e7b153e7(00:00) Why Human Resources Matter Most (01:46) Introducing Dr Mary-Clare Race (04:00) The Psychology of Workplace Toxicity (06:06) The “Toxic Triangle” Explained (07:48) Turning Toxic Cultures Into Thriving Ones (10:40) Why DE&I Slips During Economic Pressure (13:16) The Backlash Against DE&I (15:12) Building Belonging Through Human Connection (16:45) Remote Work's Impact on Toxicity (18:27) The Connection Crisis at Work (22:19) Do Playground Bullies Become Business Leaders? (26:25) How Early Experiences Shape Leadership Styles (28:56) Empathy, Resilience & Self-Awareness in Leadership (31:46) Micro-Coaching Moments for Busy Leaders (33:30) Leading Multi-Generational Workforces (36:42) Supporting Caregivers and Working Parents (39:26) AI in Coaching and Leadership Development (43:45) Final Advice for HR Leaders
Send us a text
Do you know what’s really in your supplements… or your sourdough? In today’s episode of The Nutrition Couch, Susie and Leanne dive into four hot-button nutrition topics making waves right now — from vitamin overload to supermarket marketing tricks. Here’s what we cover:
What if the biggest threat to your workplace isn't external—but staring back at you in the mirror?In this powerful episode of Shedding the Corporate Bitch, Bernadette Boas dives deep into the hidden signs of toxic leadership, team behavior, and culture. You'll learn how to identify red flags before they cost you your best people, and discover proven strategies to transform a dysfunctional team into a powerhouse culture that thrives.Whether you're a corporate leader, HR professional, or aspiring change agent, this episode will challenge your thinking, sharpen your awareness, and equip you with actionable steps to create a high-performing, healthy team environment.What you'll learn in this episode:The silent killers of team trust and performanceHow leaders unintentionally feed toxic culturesStrategies for confronting and eradicating toxic behaviorsWhy culture change starts with inner work, not policyThe essential steps to build a team that's engaged, empowered, and loyalTimestamps / Chapters:0:00 – Introduction: The hidden threat of toxic leadership 1:15 – My own wake-up call: Realizing I was the problem 2:30 – What “toxic behavior” really means in the workplace 5:00 – Key questions every leader must ask themselves 6:20 – Hidden signs of a toxic individual or team 21:00 – Identifying and addressing one key toxic behavior 33:00 – The hallmarks of a high-functioning culture 36:10 – Why real change takes time and persistence 37:00 – Call to action: Start the conversation and lead boldlyCall to Action:If you're ready to become a powerhouse change agent, share this episode with your team, colleagues, and HR partners. Start the brave conversations that will transform your workplace into one where people love to contribute, grow, and thrive.
If you're curious as to if you have any stored emotions or trauma that might be causing your illness, preventing you from achieving your or even just showing up as the best, authentic version of yourself, I invite you to take my free Stored Emotions and Trauma Quiz What happens when you outgrow the people around you?In this episode, I talk with Lupita, who I've known for over six years, about how her approach to work and relationships has shifted since she first started her job. She shares what it was like to go from being involved in workplace drama to learning how to handle conflict, set boundaries, and keep her focus on her job. We talk about navigating friendships after a promotion, dealing with gossip, and why she's learned to be okay with not everyone liking her.You'll Learn:Why you might feel inclined to engage in workplace dramaHow to identify areas of growth so you can be the solution and not the problemTips on how to shift from being the gossiper to the leaderHow gossip can quietly damage trust, morale, and professional reputationWhy setting boundaries between friendship and leadership mattersThe surprising link between personal maturity and handling workplace conflictWhat changes when you learn to bring problems to HR instead of fueling gossipHow early life experiences and upbringing can influence work behaviorThe mental shift that happens when you accept not everyone will like youWhy being professional doesn't mean being cold or unfriendlyHow to turn workplace challenges into opportunities for self-awareness and growthTimestamps: [00:00] Introduction [06:00] Getting caught up in workplace drama and its impact [10:47] Learning to avoid gossip and protect professional relationships [15:00] Handling criticism and rumors without reacting emotionally [20:00] Using workplace conflict as a teaching opportunity for staff [27:00] The influence of upbringing and social media on work behavior [33:00] Recognizing how words spread and fuel the “telephone game” [40:00] Challenges of leadership when former peers are now staff [46:00] Choosing professionalism even with people you don't like [54:00] The long-term impact of gossip on personal and work life [1:01:00] Accepting mistakes and moving forward in a leadership roleFind More From Dr. Stephanie Davis:Dr. Stephanie Davis | WebsiteQuantum Rx | InstagramQuantum Rx | Skool
In today's episode, Dr. Killeen talks about one of the hardest parts of leadership—dealing with toxic team members and the ripple effects they create. From recognizing early warning signs to having honest conversations and setting clear expectations, Addison walks through how to handle negativity with both empathy and decisiveness. If you've ever felt the energy shift in your office or sensed something was off, this episode is for you. Because protecting your culture isn't just important—it's essential.To learn more about Dr. Killeen and his new book, The Shift, or to connect with him, check out www.AddisonKilleen.com.
Dr. Hope Rugo and Dr. Kamaria Lee discuss the prevalence of financial toxicity in cancer care in the United States and globally, focusing on breast cancer, and highlight key interventions to mitigate financial hardship. TRANSCRIPT Dr. Hope Rugo: Hello, and welcome to By the Book, a podcast series from ASCO that features engaging conversations between editors and authors of the ASCO Educational Book. I'm your host, Dr. Hope Rugo. I'm the director of the Women's Cancer Program and division chief of breast medical oncology at the City of Hope Cancer Center, and I'm also the editor-in-chief of the Educational Book. Rising healthcare costs are causing financial distress for patients and their families across the globe. Patients with cancer report financial toxicity as a major impediment to their quality of life, and its association with worse outcomes is well documented. Today, we'll be discussing how patients with breast cancer are uniquely at risk for financial toxicity. Joining me for this discussion is Dr. Kamaria Lee, a fourth-year radiation oncology resident and health equity researcher at MD Anderson Cancer Center and a co-author of the recently published article titled, "Financial Toxicity in Breast Cancer: Why Does It Matter, Who Is at Risk, and How Do We Intervene?" Our full disclosures are available in the transcript of this episode. Dr. Lee, it's great to have you on this podcast. Dr. Kamaria Lee: Hey, Dr. Rugo. Thank you so much for having me. I'm excited to be here today. I also would like to recognize my co-authors, Dr. Alexandru Eniu, Dr. Christopher Booth, Molly MacDonald, and Dr. Fumiko Chino, who worked on this book chapter with me and did a fantastic presentation on the topic at ASCO this past year. Dr. Hope Rugo: Thanks very much. We'll now just jump into the questions. We know that rising medical costs contribute to a growing financial burden on patients, which has [GC1] [JG2] been documented to contribute to lower quality-of-life, compromised clinical care, and worse health outcomes. How are patients with breast cancer uniquely at risk for financial toxicity? How does the problem vary within the breast cancer population in terms of age, racial and ethnic groups, and those who have metastatic disease? Dr. Kamaria Lee: Breast cancer patients are uniquely at risk of financial toxicity for several reasons. Three key reasons are that breast cancer often requires multimodal treatment. So this means patients are receiving surgery, many receive systemic therapies, including hormonal therapies, as well as radiation. And so this requires care coordination and multiple visits that can increase costs. Secondly, another key reason that patients with breast cancer are uniquely at risk for financial toxicity is that there's often a long survivorship period that includes long-term care for toxicities and continued follow-ups, and patients might also be involved in activities regarding advocacy, but also physical therapy and mental health appointments during their prolonged survivorship, which can also add costs. And a third key reason that patients with breast cancer are uniquely at risk for financial toxicity is that the patient population is primarily women. And we know that women are more likely to have increased caregiver responsibilities while also potentially working and managing their treatments, and so this is another contributor. Within the breast cancer population, those who are younger and those who are from marginalized racial/ethnic groups and those with metastatic disease have been shown to be at an increased risk. Those who are younger may be more likely to need childcare during treatment if they have kids, or they're more likely to be employed and not yet retired, which can be disrupted while receiving treatment. And those who are racial/ethnic minorities may have increased financial toxicity due to reasons that exist even after controlling for socioeconomic factors. And some of these reasons have been shown to be increased risk of job or income loss or transportation barriers during treatment. And lastly, for those with metastatic breast cancer, there can be ongoing financial distress due to the long-term care that is needed for treatment, and this can include parking, transportation, and medications while managing their metastatic disease. Dr. Hope Rugo: I think it is really important to understand these issues as you just outlined. There has been a lot of focus on financial toxicity research in recent years, and that has led to novel approaches in screening for financial hardship. Can you tell us about the new screening tools and interventions and how you can easily apply that to clinical practice, keeping in mind that people aren't at MD Anderson with a bunch of support and information on this but are in clinical practice and seeing many, many patients a day with lots of different cancers? Dr. Kamaria Lee: You're exactly right that there is incredible nuance needed in understanding how to best screen for financial hardship in different types of practices. There are multiple financial toxicity tools. The most commonly used tool is the Comprehensive Score for Financial Toxicity, also known as the COST tool. In its full form, it's an 11-item survey. There's also a summary question as well. And these questions look at objective and subjective financial burden, and it uses a five-point Likert scale. For example, one question on the full form is, "I know that I have enough money in savings, retirement, or assets to cover the cost of my treatment," and then patients are able to respond "not at all" to "very much" with a threshold score for financial toxicity risk. Of course, as you noted, one critique of having an 11-item survey is that there's limited time in patient encounters with their providers. And so recently, Thom et al validated an abbreviated two-question version of the COST tool. This validation was done in an urban comprehensive cancer center, and it was found to have a high predictive value to the full measure. We note which two questions are specifically pulled from the full measure within the book chapter. And this is one way that it can be easier for clinicians who are in a busier setting to still screen for financial toxicity with fewer questions. I also do recommend that clinicians who know their clinic's workflow the best, work with their team of nurses, financial navigators, and others to best integrate the tool into their workflow. For some, this may mean sending the two-item survey as a portal message so that patients can answer it before consults. Other times, it could mean having it on the tablet that can be done in the clinic waiting room. And so there are different ways that screening can be done, even in a busy setting, and acknowledging that different practices have different amounts of resources and time. Dr. Hope Rugo: And where would people access that easily? I recognize that that information is in your chapter, or your article that's on PubMed that will be linked to this podcast, but it is nice to just know where people could easily access that online. Dr. Kamaria Lee: Yes, and so you should be able to Google ‘the COST measure', and then there is a website that also has the forms as well. So it's also beyond the book chapter, Googling ‘the COST measure', and then online they would be able to find access to the form. Dr. Hope Rugo: And how often would you do that screening? Dr. Kamaria Lee: So, I think it's definitely important that we are as proactive as possible. And so initially, I recommend that the screening happens at the time of diagnosis, and so if it's done through the portal, it can be sent before the initial consult, or again, however, is best in the workflow. So at the time of diagnosis and then at regular intervals, so throughout the treatment process, but then also into the follow-up period as well to best understand if there's still a financial burden even after the treatments have been completed. Dr. Hope Rugo: I wonder if in the metastatic setting, you could do it at the change of treatment, you know, a month after somebody's changed treatment, because people may not be as aware of the financial constraints when they first get prescribed a drug. It's more when you hear back from how much it's going to cost. And leading into that, I think it's, what do you do with this? So, you know, this cost conversation is really important. You're going to be talking to the patient about the cost considerations when you, for example, see that there are financial issues, you're prescribing treatments. How do we implement impactful structured cost conversations with our breast cancer patients, help identify financial issues, and intervene? How do we intervene? I mean, as physicians often we aren't really all that aware, or providers, of how to address the cost. Dr. Kamaria Lee: Yes, I agree fully that another key time when to screen for financial toxicity is at that transition between treatments to best understand where they're at based off of what they've received previously for care, and then to anticipate needs when changing regimens, such as like you said in the metastatic setting. As we're collecting this information, you're right, we screen, we get this information, and what do we do? I do agree that there is a lack of knowledge among us clinicians of how do we manage this information. What is insurance? How do we manage insurance and help patients with insurance concerns? How do we help them navigate out-of-pocket costs or even the indirect costs of transportation? Those are a lot of things that are not covered in-depth in traditional medical training. And so it can be overwhelming for a lot of clinicians, not only due to time limitations in clinic, but also just having those conversations within their visit. And so what I would say, a key thing to note, is that this is another area for multidisciplinary care. So just as we're treating patients in a multidisciplinary way within oncology as we work with our medical oncology, surgical colleagues across the board, it's knowing that this is another area for multidisciplinary care. So the team members include all of the different oncologists, but it also includes team members such as financial counselors and navigators and social workers and even understanding nonprofit partners who we have who have money that can be set aside to help reduce costs for certain different aspects of treatment. Another thing I will note is that most patients with breast cancer often say they do want to have these conversations still with their clinicians. So they do still see a clinician as someone that can weigh in on the costs of their treatment or can weigh in on this other aspect of their care, even if it's not the actual medication or the radiation. And so patients do desire to hear from their clinicians about this topic, and so I think another way to make it feel less overwhelming for clinicians like ourselves is to know that even small conversations are helpful and then being knowledgeable about within your institution or, like I said, outside of it with nonprofits, being aware of who can I refer this patient to for continued follow-up and for more detailed information and resources. Dr. Hope Rugo: Are those the successful interventions? It's really referring to financial navigators? How do people identify? You know, in an academic center, we often will sort of punt this to social workers or our nurse navigators. What about in the community? What's a successful intervention example of mitigating financial toxicity? Dr. Kamaria Lee: I agree completely that the context at which people are practicing is important to note. So as you alluded to, in some bigger systems, we do have financial navigators and this has been seen to be successful in providing applications and assisting with applications for things such as pharmaceutical assistance, insurance applications, discount opportunities. Another successful intervention are financial toxicity tumor boards, which I acknowledge might not be able to exist everywhere. But where this is possible, multidisciplinary tumor boards that include both doctors and nurses and social workers and any other members of the care team have been able to effectively decrease patients' personal spending on care costs and decrease co-pays through having a dedicated time to discuss concerns as they arise or even proactively. Otherwise, I think in the community, there are other interventions in regards to understanding different aspects of government programs that might be available for patients that are not, you know, limited to an institution, but that are more nationally available, and then again, also having the nonprofit, you know, partnerships to see other resources that patients can have access to. And then I would also say that the indirect costs are a significant burden for many patients. So by that, I mean even parking costs, transportation, childcare. And so even though those aren't interventions necessarily with someone who is a financial navigator, I would recommend that even if it's a community practice, they discuss ways that they can help offset those indirect costs with patients with parking or if there are ways to help offset transportation costs or at least educate patients on other centers that may be closer to them or they can still receive wonderful care, and then also making sure that patients are able to even have appointments scheduled in ways that are easier for them financially. So even if someone's receiving care out in the community where there's not a financial navigator, as clinicians or our scheduling teams, sometimes there are options to make sure if a patient wants, visits are more so on one day than throughout the week or many hours apart that can really cause loss of income due to missed work. And so there are also kind of more nuanced interventions that can happen even without a financial navigation system in place. Dr. Hope Rugo: I think that those are really good points and it is interesting when you think about financial toxicity. I mean, we worry a lot when patients can't take the drugs because they can't afford them, but there are obviously many other non-treatment, direct treatment-related issues that come up like the parking, childcare, tolls, you know, having a working car, all those kinds of things, and the unexpected things like school is out or something like that that really play a big role where they don't have alternatives. And I think that if we think about just drug costs, I think those are a big issue in the global setting. And your article did address financial toxicity in the global setting. International financial toxicity rates range from 25% of patients with breast cancer in high-income countries to nearly 80% in low- and middle-income countries or LMICs. You had cited a recent meta-analysis of the global burnout from cancer, and that article found that over half of patients faced catastrophic health expenditures. And of course, I travel internationally and have a lot of colleagues who are working in oncology in many countries, and it is really often kind of shocking from our perspective to see what people can get coverage for and how much they have to pay out-of-pocket and how much that changes, that causes a lot of disparity in access to healthcare options, even those that improve survival. Can you comment on the global impact of this problem? Dr. Kamaria Lee: I am glad that you brought this up for discussion as well. Financial toxicity is something that is a significant global issue. As you mentioned, as high as 80% of patients with breast cancer in low- and middle-income countries have had significant financial toxicity. And it's particularly notable that even when looking at breast cancer compared to other malignancies around the world, the burden appears to be worse. This has been seen even in countries with free universal healthcare. One example is Sri Lanka, where they saw high financial toxicity for their patients with breast cancer, even with this free universal healthcare. But there were also those travel costs and just additional out-of-hospital tests that were not covered. Also, literature in low- and middle-income countries shows that patients might also be borrowing money from their social networks, so from their family and their friends, to help cover their treatment costs, and in some cases, people are making daily food compromises to help offset the cost of their care. So there is a really large burden of financial toxicity generally for cancer globally, but also specifically in breast cancer, it warrants specific discussion. In the meta-analysis that you mentioned, they identified key risk factors of financial toxicity globally that included people who had a larger family size, a lower income, a lack of insurance, longer disease duration, so again, the accumulation of visits and costs and co-pay over time, and those who had multiple treatments. And so in the global setting, there is this significant burden, but then I will also note that there is a lack of literature in low-income countries on financial toxicity. So where we suspect that there is a higher burden and where we need to better understand how it's distributed and what interventions can be applied, especially culturally specific interventions for each country and community, there's less research on this topic. So there is definitely an increased need for research in financial toxicity, particularly in the global setting. Dr. Hope Rugo: Yes, and I think that goes on to how we hope that financial toxicity researchers will have approaches to large-scale multi-institutional interventions to improve financial toxicity. I think this is an enormous challenge, but one of the SWOG organizations has done some great work in this area, and a randomized trial addressing cancer-related financial hardship through the delivery of a proactive financial navigation intervention is one area that SWOG has focused on, which I think is really interesting. Of course, that's going to be US-based, which is how we might find our best paths starting. Do you think that's a good path forward, maybe that being able to provide something like that across institutions that are independent of being a cancer only academic center, or more general academic center, or a community practice? You know, is finding ways to help patients with breast cancer and their families understand and better manage financial aspects of cancer care on a national basis the next approach? Dr. Kamaria Lee: Yes, I agree that that is a good approach, and I think the proactive component is also key. We know that patients that are coming to us with any cancer, but including breast cancer, some of them have already experienced a financial burden or have recently had a job loss before even coming to us and having the added distress of our direct costs and our indirect costs. So I think being proactive when they come to us in regards to the additional burden that their cancer treatments may cause is key to try to get ahead of things as much as we can, knowing that even before they've seen us, there might be many financial concerns that they've been navigating. I think at the national level, that allows us to try to understand things at what might be a higher level of evidence and make sure that we're able to address this for a diverse cohort of patients. I know that sometimes the enrollment can be challenging at the national level when looking at financial toxicity, as then we're involving many different types of financial navigation partners and programs, and so that can maybe make it more complex to understand the best approaches, but I think that it can be done and can really bring our understanding of important financial toxicity interventions to the next level. And then the benefit to families with the proactive component is just allowing them to feel more informed, which can help decrease anticipation, anxiety related to anticipation, and allow them to help plan things moving forward for themselves and for the whole family. Dr. Hope Rugo: Those are really good points and I wonder, I was just thinking as you were talking, that having some kind of a process where you could attach to the electronic health record, you could click on the financial toxicity survey questions that somebody filled out, and then there would be a drop-down menu for interventions or connecting you to people within your clinic or even more broadly that would be potential approaches to manage that toxicity issue so that it doesn't impact care, you know, that people aren't going to decide not to take their medication or not to come in or not to get their labs because of the cost or the transportation or the home care issues that often are a big problem, even parking, as you pointed out, at the cancer center. And actually, we had a philanthropic donor when I was at UCSF who donated a large sum of money for patient assistance, and it was interesting to then have these sequential meetings with all the stakeholders to try and decide how you would use that money. You need a big program, you need to have a way of assessing the things you can intervene with, which is really tough. In that general vein, you know, what are the governmental, institutional, and provider-level actions that are required to help clinicians do our best to do no financial harm, given the fact that we're prescribing really expensive drugs that require a lot of visits when caring for our patients with breast cancer in the curative and in the metastatic setting? Dr. Kamaria Lee: At the governmental level, there are patient assistant programs that do exist, and I think that those can continue and can become more robust. But I also think one element of those is oftentimes the programs that we have at the government level or even institutional levels might have a lot of paperwork or be harder for people with lower literacy levels to complete. And so I think the government can really try to make sure that the paperwork that is given, within reason, with all the information they need, but that the paperwork can be minimized and that there can be clear instructions, as well as increased health insurance options and, you know, medical debt forgiveness as more broad just overall interventions that are needed. I think additionally, institutions that have clinical trials can help ensure that enrollment can be at geographically diverse locations. Some trials do reimburse for travel costs, of course, but sometimes then patients need the reimbursement sooner than it comes. And so I think there's also those considerations of more so upfront funds for patients involved in clinical trials if they're going to have to travel far to be enrolled in that type of care or trying to, again, make clinical trials more available at diverse locations. I would also say that it's important that those who design clinical trials use what is known as the “Common Sense Oncology” approach of making sure that they're designed in minimizing the use of outcomes that might have a smaller clinical benefit but may have a high financial toxicity. And that also goes to what providers can do, of understanding what's most important to a particular patient in front of them, what outcomes and what benefit, or you know, how many additional months of progression-free survival or things like that might be important to a particular patient and then also educating them and discussing what the associated financial burden is just so that they have the full picture as they make an informed decision. Dr. Hope Rugo: As much as we know. I mean, I think that that's one of the big challenges is that as we prescribe these expensive drugs and often require multiple visits, even, you know, really outside of the clinical trial setting, trying to balance the benefit versus the financial toxicity can be a huge challenge. And that's a big area, I think, that we still need help with, you know. As we have more drugs approved in the early-stage setting and treatments that could be expensive, oral medications, for example, in our Medicare population where the share of cost may be substantial upfront, you know, with an upfront cost, how do we balance the benefits versus the risk? And I think you make an important point that discussing this individually with patients after we found out what the cost is. I think warning patients about the potential for large out-of-pocket cost and asking them to contact us when they know is one way around this. You know, patients feeling like they're sort of out there with a prescription, a recommendation from their doctor, they're scared of their cancer, and they have this huge share of cost that we didn't know about. That's one challenge, and I don't know if there's any suggestions you have about how one should approach that communication with the patient. Dr. Kamaria Lee: Yes, I think part of it is truly looking at each patient as an individual and asking how much they want to know, right? So we all know that patients, some who want more information, some want less, and so I think one way to approach that is asking them about how much information do they want to know, what is most helpful to them. And then also, knowing that if you're in a well-resourced setting that does have the social workers and financial navigators, also making sure it's integrated in the multidisciplinary setting and so that they know who they can go to for what, but also know that as a clinician, you're always happy for them to bring up their concerns and that if it's something that you're not aware of, that you will connect them to the correct multidisciplinary team members who can accurately provide that additional information. Dr. Hope Rugo: Do you have any other additional comments that you'd like to mention that we haven't covered? I think the idea of a financial toxicity screen with two questions that could be implemented at change of therapy or just periodically throughout the course of treatment would be a really great thing, but I think we do need as much information on potential interventions as possible because that's really what challenges people. It's like finding out information that you can't handle. Your article provides a lot of strategies there, which I think are great and can be discussed on a practice and institutional level and applied. Dr. Kamaria Lee: Yeah, I would just like to thank you for the opportunity to discuss such an important topic within oncology and specifically for our patients with breast cancer. I agree that it can feel overwhelming, both for clinicians and patients, to navigate this topic that many of us are not as familiar with, but I would just say that the area of financial toxicity is continuing to evolve as we gather more information on most successful interventions and that our patients can often inform us on, you know, what interventions are most needed as we see them. And so you can have your thinking about it as you see individual patients of, "This person mentioned this could be more useful to them." And so I think also learning from our patients in this space that can seem overwhelming and that maybe we weren't all trained on in medical school to best understand how to approach it and how to give our patients the best care, not just medically, but also financially. Dr. Hope Rugo: Thank you, Dr. Lee, for sharing your insights with us today. Our listeners will find a link, as I mentioned earlier, to the Ed Book article we discussed today in the transcript of this episode. I think it's very useful, a useful resource, and not just for providers, but for clinic staff overall. I think this can be of great value and help open the discussion as well. Dr. Kamaria Lee: Thank you so much, Dr. Rugo. Dr. Hope Rugo: And thanks to our listeners for joining us today. Please join us again next month on By the Book for more insightful views on topics you'll be hearing at Education Sessions from ASCO meetings and our deep dives into new approaches that are shaping modern oncology. Thank you. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Follow today's speakers: Dr. Hope Rugo @hope.rugo Dr. Kamaria Lee @ lee_kamaria Follow ASCO on social media: @ASCO on X (formerly Twitter) ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. Hope Rugo: Honoraria: Mylan/Viatris, Chugai Pharma Consulting/Advisory Role: Napo Pharmaceuticals, Sanofi, Bristol Myer Research Funding (Inst.): OBI Pharma, Pfizer, Novartis, Lilly, Merck, Daiichi Sankyo, AstraZeneca, Gilead Sciences, Hoffman La-Roche AG/Genentech, In., Stemline Therapeutics, Ambryx Dr. Kamaria Lee: No relationships to disclose
Anticipating and managing CDK4/6 inhibitor toxicities in HR+ HER2- breast cancer is essential to improving patient quality of life and optimizing clinical outcomes. In this episode, CANCER BUZZ speaks with Diana Van Ostran, PharmD, BCOP, clinical pharmacy specialist – breast clinic at Miami Cancer Institute, Baptist Health South Florida, about strategies to monitor and manage treatment-related adverse events in patients with early-stage and metastatic breast cancer receiving CDK4/6 inhibitors. She discusses the importance of individualized care and robust patient education around lifestyle and dietary techniques to improve tolerance of this treatment. Diana Van Ostran, PharmD, BCOP Clinical Pharmacy Specialist – Breast Clinic Miami Cancer Institute Baptist Health South Florida Miami, FL “Clinical pharmacists play a vital role in managing the patient's treatment. Because, as we know, if you're having excessive side effects, patients are going to be less likely to take their medications.” Resources: ACCC Adverse Event Management for CDK Inhibitors in HR+ Breast Cancer ACCC CDK Inhibitors Management Miami Cancer Institute ACCC Spotlight on Miami Cancer Institute: The Role of a Breast Cancer Clinical Pharmacy Specialist for CDK4/6 Inhibitor Management
Welcome back to the Oncology Brothers podcast! In this episode, Drs. Rahul and Rohit Gosain are joined by world-renowned medical oncologist Dr. Monty Pal from the City of Hope. Together, they dived deep into the management of side effects associated with tyrosine kinase inhibitors (TKIs) and HIF-2 alpha inhibitors used in treating renal cell carcinoma (RCC). Episode Highlights: • Understanding TKIs and HIF-2 Inhibitors: A discussion on the available oral treatment options for RCC, including cabozantinib, lenvatinib, and axitinib. • Dosing Strategies: Insights on starting doses, titration, and the importance of managing side effects without compromising quality of life. • Common Side Effects: hypertension, diarrhea, fatigue, and how they relate to the class effect of these medications. • Clinical Pearls: Dr. Pal shared valuable tips on managing toxicities, including the use of treatment breaks and supportive care strategies. • Second-Line Treatments: A look at tivozanib and belzutifan, including their unique side effects and management strategies. Join us as we emphasized the importance of maintaining quality of life for patients undergoing treatment for metastatic RCC. Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Don't forget to check out our other episodes for more insights on treatment algorithms, conference highlights, and challenging cases from the community.
Scaling a SaaS startup isn't just about product-market fit or revenue numbers, it's about people, culture, and leadership. In this episode of the Grow Your B2B SaaS podcast, host Joran Hofman sits down with Hugo Pereira, the Co-founder of Ritmoo and author of Teams in Hell: How to End Bad Management, to discuss ways of building SaaS partnerships that actually drive revenue.If you've ever wondered why some startups skyrocket to $100 million ARR while others stall at $1 million, the difference often lies in what happens behind the scenes. Hugo has helped scale multiple companies and has seen it all the pitfalls, the patterns, and the principles that actually work. In this episode, brought to you by SaaStock, Hugo shares hard-earned insights for founders who want to scale with clarity, not chaos.As a valued listener of the Grow Your B2B SaaS podcast, we've got something special for you! As a valued participant, you have the exclusive opportunity to get a 30% discount on tickets to SaaStock Europe this October - the leading conference for AI & SaaS founders, investors, and leaders.Key Timecodes(0:00) - Introduction: Building Structure in Startups and the Importance of Customer Feedback(1:00) - Episode Overview: What SaaS Companies Fail to Do in Culture and Team Dynamics(1:10) - Guest Introduction: Hugo Pereira, Co-founder of Rytmo and Author of "Teams in Hell"(1:35) - Scaling Experience: Helping Companies Grow from $1 Million to $100 Million in Revenue(2:05) - Story of Startup Failure: Culture and Team Challenges in a B2B SaaS Company(3:14) - Founding Team Impact: Old-School Mindsets and Lack of Customer Validation(4:23) - Realities of Startup Culture: Authority-Driven Environments and Their Effects(5:40) - Importance of Early Culture: Building Trust vs. Toxicity from Day Zero(6:39) - Defining Culture: Values, Behaviors, Rituals, and Systems in an Organization(8:03) - Common Failures in Scaling: Process Breakdowns, Founder Control, Lack of Alignment(9:24) - Complexity of Scaling: Need for Structure and Clear Ownership in Growing Teams(11:27) - Misconceptions of Growth: Confusing Traction with Understanding and Clarity(12:06) - The Evolution of Startups: From Hustle to Frameworks and Repeatable Systems(13:38) - Importance of Alignment: The Why Now Story and Trust Building in Teams(14:56) - Customer Ties: The Role of Deep Customer Relationships in Scaling Success(17:57) - Feedback and Misalignment: Warning Signs of Cultural and Team Misalignment(19:20) - Remote Work Challenges: Maintaining Alignment and Feedback in Hybrid Setups(21:23) - Hero Culture Warning: Overworking and Glorifying Output without Results(22:00) - Scaling Trust and Accountability: Shared Expectations and Frequent Feedback(25:03) - Feedback Loops: Formal and Informal Check-Ins to Foster Open Communication(28:59) - Leadership Pitfalls: Behaviors That Can Kill Morale and Momentum(32:17) - Best Advice for SaaS Founders: Never Lose Sight of Your Initial Why(33:38) - Future of SaaS: Preparing for Slower Deal Cycles and Community Engagement(35:27) - Advice for Early-Stage SaaS: Prioritize Conversations Over Conversions(36:55) - Scaling to 10 Million ARR: Focus on Repeatable Motions and Community Building(41:15) - Where to Find Hugo's Book: "Teams in Hell" Available on Amazon
Join us today for a unique Mormon Stories episode that is the first of its kind. Myndee Tollefson was born in Bountiful, Utah to an orthodox Mormon family. At just 19, she became pregnant and, feeling immense pressure from the Church and her family, gave her baby up for adoption through LDS Family Services—only to later discover that her child's life in the adoptive family was not what the Church promised.Topics include:-Toxicity of purity culture-Unplanned pregnancy in Mormonism-Harsh backlash from her family and LDS community-Adoption within the LDS Family services program-The church's role in facilitating and encouraging adoption-Being a "birth mom"-Troubled teen culture within MormonismHer story sheds light on the emotional and spiritual costs of institutional coercion, and the healing that comes with breaking free from this control. ___________________YouTubeMormon Stories Thanks Our Generous Donors!Help us continue to deliver quality content by becoming a donor today:One-time or recurring donation through DonorboxSupport us on PatreonPayPalVenmoOur Platforms:YouTubePatreonSpotifyApple PodcastsSocial Media:Insta: @mormstoriesTikTok: @mormonstoriespodcastJoin the DiscordContact us:MormonStories@gmail.comPO Box 171085, Salt Lake City, UT 84117
Contributor: Megan Hurley MD Educational Pearls: Acute toxicity of heavy metals: Gastrointestinal upset is the most common presentation Chronic toxicity of heavy metals: Symptoms depend on the metal ingested Increased risk of cancer Altered mentation Developmental delays (in children) Kidney failure Four heavy metals that are tested for in a general panel and their sources: Lead Old paint (homes built before 1977) or some older toys Pipes of older homes or those with corrosive agents May obtain testing kits from home improvement stores to test water supply Mercury Previously in thermometers, although much less common now Compact fluorescent lightbulbs, LCD screens, and some batteries Large predatory fish like tuna, swordfish, dolphins, and shark Arsenic sources Most commonly found in pesticides Contaminated groundwater (especially private wells) Cadmiun sources Most commonly found in tobacco smoke Batteries Metal plating and welding Additional heavy metals that require specific testing Chromium, Nickel, & Thallium Thallium is found in rodenticides, pesticides, and fireworks Management of heavy metal toxicity depends on the intoxicant Generally, chelation therapy is used for acute and severe cases Arsenic: dimercaprol or DMSA Mercury: DMPS (chronic or mild) or DMSA (severe) Lead: succimer is first line, followed by dimercaprol or EDTA References Baker BA, Cassano VA, Murray C; ACOEM Task Force on Arsenic Exposure. Arsenic Exposure, Assessment, Toxicity, Diagnosis, and Management: Guidance for Occupational and Environmental Physicians. J Occup Environ Med. 2018;60(12):e634-e639. doi:10.1097/JOM.0000000000001485 Balali-Mood M, Naseri K, Tahergorabi Z, Khazdair MR, Sadeghi M. Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic. Front Pharmacol. 2021;12:643972. Published 2021 Apr 13. doi:10.3389/fphar.2021.643972 Kinally C, Fuller R, Larsen B, Hu H, Lanphear B. A review of lead exposure source attributional studies. Sci Total Environ. 2025;990:179838. doi:10.1016/j.scitotenv.2025.179838 Jannetto PJ, Cowl CT. Elementary Overview of Heavy Metals. Clin Chem. 2023;69(4):336-349. doi:10.1093/clinchem/hvad022 Järup L. Hazards of heavy metal contamination. Br Med Bull. 2003;68:167-182. doi:10.1093/bmb/ldg032 Zhang H, Reynolds M. Cadmium exposure in living organisms: A short review. Sci Total Environ. 2019;678:761-767. doi:10.1016/j.scitotenv.2019.04.395 Summarized & Edited by Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/
TODAY ON THE ROBERT SCOTT BELL SHOW: AAP Targets Religious Exemptions, Religious Liberty Challenge, Fluoride Under FDA Scrutiny, Lead Tied to Memory Loss, Iodoformium, RFK's Vaccine Bombshell, CDC Exposes Long COVID Lie, Roots of Neurodegenerative Disorder, Gentle Parenting Backlash, Promote Free Markets, and MORE! https://robertscottbell.com/aap-targets-religious-exemptions-religious-liberty-challenge-fluoride-under-fda-scrutiny-lead-tied-to-memory-loss-iodoformium-rfks-vaccine-bombshell-cdc-exposes-long-covid-lie-roots-of-neurod/ https://boxcast.tv/view/aap-targets-religious-exemptions-fluoride-scrutinized-lead-toxicity-iodoformium-rfk-vax-bombshell-fafo---the-rsb-show-7-29-25-vynyidg3gbjwbsfsc8ee Please read this disclaimer carefully before you (“you”, “your”) use our [Your Website URL] website (“website”, “service”) operated by the [Your Business Name] (“operator”, “us”, “we”, “our”). Purpose and Character The use of copyrighted material on the website is for non-commercial, educational purposes, and is intended to provide benefit to the public through information, critique, teaching, scholarship, or research. Nature of Copyrighted Material Weensure that the copyrighted material used is for supplementary and illustrative purposes and that it contributes significantly to the user's understanding of the content in a non-detrimental way to the commercial value of the original content. Amount and Substantiality Our website uses only the necessary amount of copyrighted material to achieve the intended purpose and does not substitute for the original market of the copyrighted works. Effect on Market Value The use of copyrighted material on our website does not in any way diminish or affect the market value of the original work. We believe that our use constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the U.S. Copyright Law. If you believe that any content on the website violates your copyright, please contact us providing the necessary information, and we will take appropriate action to address your concern.
Yeeerrrr!!!!! What is going on everybody? On this episode Rob and Ericca discuss who or what makes a work environment toxic.Do you need or want some advice? Did you recently celebrate something important? Did you have a spicy interaction with someone? If so, we want to share your story. Submit your story for our new segment " Sharing Experiences" here:rob@fmepodcast.com or admin@fmepodcast.com Follow us on Instagram:The show: fme_podcastRob: komplete_visionCarl Vann: carljvannPass The Peaz App: passthepeazapphttps://www.passthepeaz.app/Download the Alive Podcast App where you can subscribe and support us:IOS: Download the Alive Podcast App on IOSAndroid: Download the Alive Podcast App on AndroidAffiliate Links:Manage your business communication like we do using Google Workspace:Get 10% off of your first year of Google Workspace by clicking here!Support The Show By Shopping With Our AffiliatesCheck Out Garner's GardenAffiliate code: FmepodcastMusic by:Romo:Support Romo' MusicJenova 7:Support Jenova 7's MusicBaskaat:Support Baaskat's MusicJ Create:Support J Create's Music
00:00 - 03:15 - INTRO (CHASE YOUR DREAMS)03:16 - 16:04 - JUDGE A BOOK BY ITS COVER16:05 - 18:03 - AMERICAN'S HAVE A CULTURE OF SHARING THIER LADIES 18:04 - 22:22 - THE BAD B'S OF BALTIMORE & LIVERPOOL22:23 - 30:45 - I DIDN'T GET TO PACK ANY TOYS30:46 - 34:48 - THE STUDY OF THE MYSTICS 34:49 - 41:12 - LET ME LOVE YOU - GREATNESS & TOXICITY 41:13 - 43:47 - JUST A FRIEND WAS MEANT TO BE USHERS SONG43:48 - 46:25 - £1 INVESTMENT, LET US ALL KNOW46:26 - 52:56 - RNB BLIND RANKING52:57 - 55:45 - STAYING CONNECTED55:46 - 57:02 - TURNING DOWN JAY-Z57:03 - 01:01:01 - BRA'S AND PANTIES ON STAGE01:01:02 - 01:07:02 - I HAD TO RESTRUCTURE MY LIFE01:07:03 - 01:11:40 - THE SOUND OF RNB01:11:41 - 01:13:45 - THE FUTURE OF STREAMING WILL BE FAIR FOR ARTISTS 01:13:46 - 01:16:40 - THE SUPER RNB GROUP01:16:41 - 01:27:56 - TRIVIA Join this channel to get access to perks:https://www.youtube.com/channel/UCOIOo7ybnNFNdwjSCgYDtOw/joinWater2 - https://water2.com/FREDSANTANA use code 90SBABY at checkoutCheck out our Amazon Storefront - https://www.amazon.co.uk/shop/90sbabyshow/list/CA7MV366T30L?ref_=cm_sw_r_cp_ud_aipsflist_CJP85NJ95R280Z6C6NMZPO Box 5038 HORNCHURCH RM12 9JX Hosted on Acast. See acast.com/privacy for more information.
00:00 - 03:15 - INTRO (CHASE YOUR DREAMS)03:16 - 16:04 - JUDGE A BOOK BY ITS COVER16:05 - 18:03 - AMERICAN'S HAVE A CULTURE OF SHARING THIER LADIES 18:04 - 22:22 - THE BAD B'S OF BALTIMORE & LIVERPOOL22:23 - 30:45 - I DIDN'T GET TO PACK ANY TOYS30:46 - 34:48 - THE STUDY OF THE MYSTICS 34:49 - 41:12 - LET ME LOVE YOU - GREATNESS & TOXICITY 41:13 - 43:47 - JUST A FRIEND WAS MEANT TO BE USHERS SONG43:48 - 46:25 - £1 INVESTMENT, LET US ALL KNOW46:26 - 52:56 - RNB BLIND RANKING52:57 - 55:45 - STAYING CONNECTED55:46 - 57:02 - TURNING DOWN JAY-Z57:03 - 01:01:01 - BRA'S AND PANTIES ON STAGE01:01:02 - 01:07:02 - I HAD TO RESTRUCTURE MY LIFE01:07:03 - 01:11:40 - THE SOUND OF RNB01:11:41 - 01:13:45 - THE FUTURE OF STREAMING WILL BE FAIR FOR ARTISTS 01:13:46 - 01:16:40 - THE SUPER RNB GROUP01:16:41 - 01:27:56 - TRIVIA Join this channel to get access to perks:https://www.youtube.com/channel/UCOIOo7ybnNFNdwjSCgYDtOw/joinWater2 - https://water2.com/FREDSANTANA use code 90SBABY at checkoutCheck out our Amazon Storefront - https://www.amazon.co.uk/shop/90sbabyshow/list/CA7MV366T30L?ref_=cm_sw_r_cp_ud_aipsflist_CJP85NJ95R280Z6C6NMZPO Box 5038 HORNCHURCH RM12 9JX Hosted on Acast. See acast.com/privacy for more information.
This week's theme: From Toxicity to Triumph This episode features Marchem Pfeiffer, a former education leader and author of Navigating Leadership from Toxicity to Triumph. The […] The post From Toxicity to Triumph with Marchem Pfeiffer appeared first on Heather Hansen Oneill.
Contributor: Jorge Chalit-Hernandez, OMS4 Educational Pearls: What is the toxic dose of acetaminophen? 7.5 grams, in an adult. The safe daily limit is 4 grams in an adult with a normally functioning liver. This is equivalent to fifteen 500mg pills. What are the symptoms of acetaminophen toxicity? First 24 hours, symptoms are non-specific e.g. nausea, vomiting, lack of appetite. Can also be asymptomatic. 24-72 hours, hepatotoxicity occurs (causing yellow skin, pruritus, abdominal pain, bleeding, and confusion) Fulminant liver failure at 72-96 hours Liver function tests (LFTs) peak at 72-96 hours. When would you give activated charcoal? Within 4 hours of ingestion. The risk of activated charcoal is that it can be very dangerous if aspirated so use with caution with a poorly mentating patient When would you give N-acetylcysteine (NAC)? The peak absorption of acetaminophen occurs at about 4 hours with acute ingestions Use the Rumack–Matthew nomogram to plot the serum level of acetaminophen versus the time since ingestion to see if you are above the treatment line. If the ingestion time is unknown then just give it. How do you dose NAC? 3 bag system: First, a 150 mg/kg bolus is administered IV over 15-60 minutes (Bag 1), then a 50 mg/kg drip is administered over 4 hours (Bag 2), then a 100 mg/kg drip is administered over the following 16 hours (Bag 3). This is the Prescott Protocol that requires three bag of IV fluids 2 bag system: There is a simplified protocol that only requires 2 bags, 200mg/kg IV over 4 hours (Bag 1) followed by 100mg/kg over 16 hours (Bag 2) Less risk of anaphylactoid reactions with a 2-bag system due to the high rate of IV NAC given in the 3 bag system. What are the endpoints for stopping NAC? If the INR is
Some people seem to have a toxic gravitational pull that affects everyone around them. And whether you're with them or not, they are either on your mind or in your space. Getting away from their influence can feel impossible.
This week: Topics covered include the financial implications of divorce, starting an investment account for children, addressing a toxic workplace, and planning for a new business venture. Farnoosh also discusses a concerning trend on TikTok about 'stay at home girlfriends' and provides practical advice on managing personal finances and investments effectively. Additional discussions include tips for college students to gain an edge in their fields and the decision-making process behind forming a business entity.
© 2020-2025 Ivy Podcast Discovery LLC
