The ability of a chemical to cause damage to life
POPULARITY
Categories
94 episodes with Toxicity
23 episodes with Toxicity
20 episodes with Toxicity
16 episodes with Toxicity
23 episodes with Toxicity
19 episodes with Toxicity
11 episodes with Toxicity
13 episodes with Toxicity
12 episodes with Toxicity
9 episodes with Toxicity
8 episodes with Toxicity
16 episodes with Toxicity
20 episodes with Toxicity
12 episodes with Toxicity
7 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
9 episodes with Toxicity
8 episodes with Toxicity
10 episodes with Toxicity
6 episodes with Toxicity
10 episodes with Toxicity
9 episodes with Toxicity
9 episodes with Toxicity
8 episodes with Toxicity
8 episodes with Toxicity
9 episodes with Toxicity
9 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
6 episodes with Toxicity
11 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
4 episodes with Toxicity
7 episodes with Toxicity
5 episodes with Toxicity
4 episodes with Toxicity
5 episodes with Toxicity
7 episodes with Toxicity
11 episodes with Toxicity
4 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
4 episodes with Toxicity
8 episodes with Toxicity
3 episodes with Toxicity
6 episodes with Toxicity
6 episodes with Toxicity
7 episodes with Toxicity
12 episodes with Toxicity
9 episodes with Toxicity
8 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
5 episodes with Toxicity
11 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
6 episodes with Toxicity
8 episodes with Toxicity
4 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
11 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
5 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
8 episodes with Toxicity
6 episodes with Toxicity
5 episodes with Toxicity
5 episodes with Toxicity
2 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
10 episodes with Toxicity
3 episodes with Toxicity
5 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
4 episodes with Toxicity
5 episodes with Toxicity
4 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
6 episodes with Toxicity
10 episodes with Toxicity
2 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
9 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
2 episodes with Toxicity
4 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
8 episodes with Toxicity
2 episodes with Toxicity
5 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
4 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
6 episodes with Toxicity
3 episodes with Toxicity
2 episodes with Toxicity
3 episodes with Toxicity
4 episodes with Toxicity
10 episodes with Toxicity
2 episodes with Toxicity
4 episodes with Toxicity
3 episodes with Toxicity
2 episodes with Toxicity
Can love be a business strategy? In this episode, we talk about how leading with love can transform your team and your bottom line. Frank Danna, a seasoned leader and marketing expert, brings his wisdom on building authentic connections in the workplace. We explore how AI can enhance, rather than replace, human creativity and the importance of creating a culture that values trust, inclusion, and vulnerability. Frank shares his personal journey from a toxic work environment to one where love and empathy drive success, offering actionable advice for leaders looking to transform their organizations. Here are some highlights: -The Power of Love in Leadership: Frank explains how love, empathy, and trust are essential to creating a successful and human-centered workplace culture. -AI and Creativity: Frank discusses how AI can free up time for leaders to be more creative and focus on what truly matters: human connections. -Building a Culture of Love: Learn the six key behaviors—Inclusion, Empathy, Vulnerability, Trust, Empowerment, and Forgiveness—that make up a culture of love in the workplace. -The Challenge of Toxicity in Leadership: Frank shares his experience of working through a toxic work culture and how a shift in leadership behavior can turn things around. -Vulnerability as a Leadership Strength: Frank highlights the importance of vulnerability in leadership and how sharing personal stories can foster real connections with your team. About the guest: Frank E. Danna is the Marketing Director at Softway and Co-Founder of Culture+, where he transforms leadership through love, empathy, and behavior-driven change. Co-author of Love as a Business Strategy and Love as a Change Strategy, Frank challenges fear-based leadership practices and champions a human-first approach. He co-created Culture Rise, a transformative leadership experience that's impacted over 6,000 leaders worldwide. Frank's expertise spans storytelling, communication strategy, and creative content, having reached 100 million viral views on Vine and co-founding GhostCodes, acquired by Softway. He's worked with brands like HBO, Twitter, and Coca-Cola, and is a sought-after speaker on culture, AI, and change. Connect with Frank: Website: www.softway.com LinkedIn: https://www.linkedin.com/in/frankdanna/ Connect with Allison: Feedspot has named Disruptive CEO Nation as one of the Top 25 CEO Podcasts on the web, and it is ranked the number 6 CEO podcast to listen to in 2025! https://podcasts.feedspot.com/ceo_podcasts/ LinkedIn: https://www.linkedin.com/in/allisonsummerschicago/ Website: https://www.disruptiveceonation.com/ #CEO #leadership #startup #founder #business #businesspodcast Learn more about your ad choices. Visit megaphone.fm/adchoices
What if the key to healing lies in forgiveness, alignment and an unexpected spiritual awakening? Dr Jane Lewis reveals how ancient Hawaiian wisdom guided her from the depths of clinical depression to a life rooted in purpose and connection. She explores the gentle power of Ho'oponopono, the importance of living in harmony with land and spirit, and why releasing old burdens can transform your wellbeing. Jane's story shows how purpose often unfolds through life's toughest lessons. If you're seeking clarity, meaning or a fresh path forward, Jane's journey offers insight, hope and a profound invitation to learn how forgiveness heals toxicity. KEY TAKEAWAY 'We underestimate the power of forgiveness. We really do. It's such a healing force. It's difficult but when you really can get to grips with it, it's such a healing force, a healing power.' ABOUT THE GUEST – DR JANE LEWIS Dr Jane Lewis is a spiritual coach, teacher and speaker who helps purpose-led women leaders reconnect with their inner power and create lasting transformation from within. Drawing on nearly 40 years' experience across the corporate, entrepreneurial and spiritual worlds, she blends ancient wisdom with modern coaching to bring clarity, alignment and deep personal growth. A lifelong explorer of the mind, body and soul, Jane works with those navigating change, seeking purpose, or ready to live more consciously. She believes real power comes from within—and that when we honour the unseen as much as the seen, true transformation becomes possible. CONNECT WITH JANE Linktree: https://linktr.ee/drjanel ABOUT THE HOST - AMY ROWLINSON Amy is a purpose and fulfilment coach, author, podcast strategist and mastermind host who empowers purpose-driven leaders to boost productivity, engagement and meaning in life and work. Through transformational conversations, Amy helps individuals overcome overwhelm and live with clarity, building living legacies along the way. WORK WITH AMY If you're interested in how purpose can help you and your business, please book a free 30 min call via https://calendly.com/amyrowlinson/call KEEP IN TOUCH WITH AMY Sign up for the weekly Friday Focus - https://www.amyrowlinson.com/subscribe-to-weekly-newsletter CONNECT WITH AMY https://linktr.ee/AmyRowlinson BUY AMY'S BOOK (Shortlisted in the 2025 Business Book Awards) * Focus on Why by Amy Rowlinson with George F. Kerr – https://amzn.eu/d/6W02HWu HOSTED BY AMY ROWLINSON DISCLAIMER The views, thoughts and opinions expressed in this podcast belong solely to the host and guest speakers. Please conduct your own due diligence. *As an Amazon Associate, Amy earns from qualifying purchases.
In episode 307, Mark & Steve respond to an all-too-common history and situation submitted by a betrayed partner. Healthy sexual intimacy after betrayal cannot simply return to what it once was; it must be rebuilt on a new foundation of authenticity and safety. Because pornography shapes the brain and rewires arousal patterns, couples often find themselves questioning what's real, what's healthy, and whether desire is rooted in connection or in old fantasy. Many partners struggle to trust, and many addicts struggle to trust themselves, creating a complex emotional landscape that must be navigated with care. This healing begins by evaluating intention and headspace—asking not what partners want to do sexually, but why they want to do it and what meaning it carries.From there, intimacy must be rebuilt through trust and transparency. Couples need to be able to talk openly about sexual preferences, fears, boundaries, and emotional needs before engaging physically. Silence or lack of objection is not consent; safety must be mutual, expressed, and explicit. Boundaries should be set outside of arousal states, and couples may need to slow down significantly—sometimes even stepping back to basics like hand-holding or non-sexual touch—while they rebuild a foundation that can hold the weight of deeper connection.Ultimately, recovering sexual intimacy after sexual toxicity is an evolving journey, not an achievement. It requires vulnerability, patience, and willingness to explore together rather than perform or comply. When couples move intentionally through this process—anchoring their sexuality in meaning, emotional presence, collaboration, and shared values—they often find themselves creating a sexual connection that is deeper and healthier than anything they experienced before recovery.For a full transcript of this podcast in article format, go to: How Do We Discover/Recover Healthy Sexual Intimacy After Sexual Toxicity and Betrayal?Learn more about Mark and Steve's revolutionary online porn/sexual addiction recovery and betrayal trauma healing program at—daretoconnectnow.comFind out more about Steve Moore at: Ascension CounselingLearn more about Mark Kastleman at: Reclaim Counseling Services
In this episode, we dive into the dating complexities unveiled between Black men and Black women on Arlette Amuli's Pop The Balloon and Find Love. Both sides showcase hypocrisy, superficiality, and controversy; however, the women on the show seem to display these traits even more. We break down the tension, the toxicity, and the possible hidden agendas at play. Tune in as we unpack it all.
If you've been doing everything right—eating clean, exercising, and taking your supplements—but still feel tired, bloated, or off, this episode is going to change the way you think about your health. I'm joined by the incredible Kim Rogers, better known online as the “Worm Queen,” who's pulling back the curtain on the hidden world of parasites and why so many of us are unknowingly affected by them. With 20+ years in Western medicine and a powerful personal healing story through Lyme, mold, and parasite infections, Kim brings both science and passion to this eye-opening conversation. You'll learn why regular parasite cleansing can be a total game-changer for your energy, digestion, skin, and overall vitality. All of us should be doing a parasite cleanse– it's safe, effective, and an incredible way to be proactive about our health. Tune in to this episode and feel empowered to take your healing into your own hands! Kim Rogers Kim worked in western medicine for over 20 years, ran 25 healthcare colleges, was a professor, author, and holds 2 healthcare degrees– all while dealing with her own chronic illnesses. In July, 2021 Kim came across a video on Tiktok talking about parasite cleansing. She gave it a try, and because it was so successful, she saw a need to help others heal. She started her company RogersHood in December 2021 making ParaFy Parasite cleanse kit to help others cleanse their bodies of unwanted parasites, candida, heavy metals, and toxins. Her mission is to help improve testing for environmental toxins for everyone! IN THIS EPISODE How Kim Rogers became an expert in understanding parasites Why parasite testing seems to be ignored in the USA Looking at how your body responds during a parasite cleanse Why it's hard to detect parasites The actual process of parasite cleansing The benefits of a 30-day cleanse program About the ParaFy cleanse and other products from RogersHood QUOTES“The herbs that we used are specifically because they're gentle and we should all be cleansing. We should all be doing this just as a proactive way, not so much as a reactive one… It's really a sad thing, the state we're seeing chronic illness at.” “60 million people in the United States have parasites that have been tested. That's through an approved lab to give us that number.” “I'm trying to teach and show people how to be sovereign over your own health and body so that you have a little more control. Chronically ill people, one of the biggest things is that I lost control over sovereignty with my own body over an illness, and over other people around me telling me what's wrong with me, and I really want to give that control back to people.” RESOURCES MENTIONED Order my new book: The Perimenopause Revolution HERE https://peri-revolution.com/ Use code ENERGIZED and get $100 on your first CAROL Bike order https://carolbike.pxf.io/GK3LaE Use code THRIVE15 and get 15% off on your Berkeley Life order https://berkeleylife.pxf.io/Vxvdja RogersHood Website → Order the ParaFy Parasite cleanse kit HERE! Kim Rogers on Instagram RELATED EPISODES #512: How Do Our Daily Exposure to Toxins Impact Our Hormones and What We Can Do About It with Dr. Wendie Trubow #455: Environmental and Everyday Toxins That Cause Hormone Deregulation with Dr. Tom O'Bryan #654: Gut Health, Hormones, and Strength: The Real Power Trio in Perimenopause with Dr. Christine Maren #635: The Connection Between Your Gut, Inflammation, Mood, and How to Start Healing Your Microbiome with Tina Anderson
Welcome to the Oncology Brothers podcast! In this episode, we dive into the management of ROS1 fusion positive non-small cell lung cancer (NSCLC) and explore the various tyrosine kinase inhibitors (TKIs) available for this rare subset of patients. Join us along with special guest Dr. Estelamari Rodriguez, a thoracic medical oncologist from Sylvester Comprehensive Cancer Center, as we discussed: • The importance of comprehensive next-generation sequencing (NGS) in management of NSCLC. • A detailed overview of ROS1 TKIs, including crizotinib, repotrectinib, entrectinib, taletrectinib. • Common side effects associated with these agents, such as fatigue, dizziness, edema, and liver toxicity. • Clinical pearls for managing adverse events and optimizing patient care. • The significance of patient education and regular follow-ups in ensuring treatment adherence and safety. Whether you're a healthcare professional or someone interested in oncology, this episode provides valuable insights into the practical aspects of treating ROS1 fusion positive NSCLC. Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Don't forget to check out our other ToxCheck episodes, conference highlights, and treatment algorithms. Subscribe for more discussions on bridging the gap between academic research and community practice! #ROS1 #NSCLC #TKIs #Crizotinib #Repotrectinib #Entrectinib #Taletrectinib #TargetedTherapy #OncologyBrothers #LungCancer
Toxicity doesn't just hurt companies—it hemorrhages them. Learn more about your ad choices. Visit podcastchoices.com/adchoices
In today's VETgirl online veterinary continuing education podcast, we interview Dr. Sara Lister, DABT, DABVT who provides us with a critical update to increase awareness of reports of severe Apoquel® (oclacitinib) toxicosis in dogs and cats during overdose situations. Tune in to hear about the latest updates for managing oclacitinib intoxication in dogs and cats, the clinical signs, and treatment recommendations!
We're talking about toxicity today.I've been seeing several cases lately where toxicity plays a role, so I thought it was time to revisit the topic. In episode 53, I covered the definition of toxicity and what it means for your horse, so you can go back and listen to it after this episode for more details. Stay tuned as I share the signs to look out for.Understanding Toxicity in HorsesToxicity in horses often develops slowly and subtly through accumulated exposure to feed contaminants, environmental chemicals, medications, or poor-quality diets. Unlike sudden poisoning, this buildup can take years to show outwardly. Younger horses may appear healthy despite ongoing exposure, but as they age, resilience drops and health issues surface, usually from around age 12 onward.Early Warning SignsSubtle behavioral and physical changes often signal toxicity. These can include fatigue, dull eyes, reduced social engagement, depression, or anxiety. Appetite changes are also key clues- horses that suddenly become picky or disinterested in food may be reacting to gut irritation or inflammation. Paying attention to these small shifts helps catch toxicity before it escalates.Behavior and the Nervous SystemToxicity can impact the nervous system, leading to high anxiety and nervousness. While horsemanship helps build horses' confidence, chronic anxiety can point to underlying health issues or an internal imbalance. Ulcers and overactive immunity often accompany this state, as pain and inflammation trigger more stress in a self-perpetuating cycle.Inflammation Inflammation is one of the most common consequences of toxicity. It often presents as laminitis or joint stiffness, even when blood work looks normal. Laminitis is particularly revealing as hoof tissues react early to systemic inflammation. Many arthritic horses may actually be struggling with toxic buildup rather than structural degeneration, and they often improve after detoxification.The LiverThe liver detoxifies all chemicals entering the body, but chronic overload eventually leads to fatigue and dysfunction. As detoxification slows, toxins accumulate, affecting hormone balance, immune strength, and overall vitality. So, even when liver enzymes appear normal, the liver may still be under strain.The Gut–Toxicity ConnectionGut health is often the first to suffer. Long-term exposure to irritants, sugars, or intolerant feeds leads to inflammation, leaky gut, and cecal acidosis. A damaged intestinal lining allows toxins to circulate through the body, causing hives, laminitis, or chronic infections. Gut inflammation also prevents nutrient absorption.Nutrient DeficiencyToxicity compounds over time. Horses with chronic gut irritation or sugar-heavy diets often experience nutrient depletion because their inflamed intestines cannot absorb key minerals and vitamins. Common Physical SignsVisible indicators include dull or coarse coats, cracking or separating hooves, weepy eyes (often linked to liver dysfunction), nasal discharge, and reduced energy. These may seem mild or age-related, but they could reflect systemic imbalance from long-term toxicity.Reversing the EffectsImprovement begins with removing toxins from feed, water, and the environment. Cleaning up the diet allows the liver, kidneys, and gut to recover. Even older horses can regain their vitality after reducing their toxicity and with good nutrition.Long-Term PreventionReducing toxicity is one of the most effective ways to prevent disease. By being mindful of feed quality, ingredient lists, and exposure sources, owners can dramatically improve their horses' health spans and overall...
Overcoming Toxicity: Amy Pease's Journey to Healing and Empowerment Passionfrompain.com About the Guest(s): Amy Pease is a multifaceted professional known for her resilience and determination to overcome a traumatic upbringing to become an inspirational figure. Raised in a manipulative and abusive adoptive family, she emerged as a beacon of hope, striving to empower others facing similar challenges. Amy is a coach, mentor, keynote speaker, podcast host, and content creator on her platform, Passion from Pain. She offers courses like "Finding Strength After Toxicity," providing guidance for individuals navigating life after toxic experiences. Her upcoming book is set to launch in February 2026, which will further delve into strategies for overcoming manipulation and mental abuse. Episode Summary: In this emotionally charged episode of The Chris Voss Show, Chris Voss sits down with Amy Pease, a survivor of a challenging upbringing, to discuss her extraordinary journey from the depths of toxicity to becoming a powerhouse of empowerment and change. Amy unveils the narrative of her past—a tale of overcoming adversity to inspire others through her multifaceted career as a coach, mentor, and speaker. During this engaging episode, Amy discusses her soon-to-be-released book, "Finding Strength After Toxicity," which offers a roadmap for those overcoming toxic environments. The episode captures Amy's transformation from enduring manipulation within her adoptive family to building a successful career. She shares how she eventually overcame her struggles with depression and anxiety, regained control of her life, and now aids others through her podcast and courses. Themes of self-accountability, resilience, and personal growth are explored. Chris Voss engages with Amy in a dialogue that goes beyond her story; together, they shed light on the intricacies of coping mechanisms and strategies for liberation from toxic ties. This engaging conversation is a beacon of hope and a manual of empowerment for listeners who may find themselves in similar situations. Key Takeaways: Amy shares her journey of escaping an emotionally abusive adoptive family and the steps she took to rebuild her life independently. The importance of recognizing non-physical forms of abuse, such as manipulation and financial control, and how to plan an escape from these situations. The power of community and support in overcoming adversity, as experienced by Amy when she started anew as a single mother. How self-accountability can be a driving force in personal healing and transformation after toxic experiences. A sneak peek into Amy's upcoming book, "Finding Strength After Toxicity," which serves as a guide for people breaking free from toxic environments. Notable Quotes: "You change your situation, and all of this goes away." - A pivotal moment of realization for Amy that inspired her transformation. "I had major depression, anxiety, a lot of shame, guilt that I was dealing with… it took me 20 years to get over it." - Amy highlighting the long-term effects of her circumstances. "If I stayed with these people, it was going to kill me, and my son would end up being raised by them." - Amy on her decision to leave her manipulative family. "There's somebody walking the path or has already walked it and they can help." - Amy emphasizing the importance of shared experiences and support. "The difference between self-accountability versus self-blame… it's the difference between making it or not." - On the critical nature of accountability in personal growth.
On this episode of CA Media Podcast, I have a special guest Shamieca Reid on as we discuss a viral TikTok video; in which someone enjoys toxicity. We come together and discuss is it true that Good Men/Women considered boring or it's our illusion. Enjoy this amazing conversation and dive in to your thoughts.#camediapod #ShamiecaReid #TikTok #Viral #GloryManz #toxicity #relationship Visionary Minds Public Relations and Media is a founding supporting sponsor of the CAMedia PodcastMake sure you get your Publicity, Digital Marketing, Writing, Media Consulting Services at visionarymindsny@gmail.com where Tammy Reese is the owner.You can listen to the podcast on the following platforms:Apple Podcast: https://podcasts.apple.com/us/podcast/ca-media-podcast/id1534508960SPOTIFY: https://open.spotify.com/show/0T1qlQvvRNpBjrFz4N5X26?si=7a873afde9ed4e34You can follow the podcast atFacebook: facebook.com/CAMediaPodcastInstagram: Instagram.com/CAMediaPodcastBlue Sky:https://bsky.app/profile/camediapodcast.bsky.socialX: https://x.com/CAMediaPodcastIF you want to be on the podcast you can email the podcast at camediapodcast@gmail.com or book on linktree at linktr.ee/CAMediaPodcast and click in the booking link.
In this episode of the Oncology Brothers podcast, we are joined by esteemed hematologists Dr. Onyee Chan from Moffitt Cancer Center and Dr. Fadi Haddad from MD Anderson to discuss the management of side effects associated with tyrosine kinase inhibitors (TKIs) used in the treatment of chronic myeloid leukemia (CML). Join us as we delve into: • An overview of the different generations of TKIs, including imatinib, dasatinib, nilotinib, bosutinib, ponatinib, and asciminib. • Common class-wide toxicities such as fatigue, hypertension, gastrointestinal symptoms, and cytopenias. • Unique side effects associated with each TKI and strategies for dose optimization. • The importance of patient education and monitoring to ensure effective management of side effects. Don't forget to check out our other ToxCheck episodes on antibody drug conjugates, CAR-T therapies, and more! Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Subscribe to the Oncology Brothers for more discussions on bridging the gap between academic research and community practice in cancer care! #CML #TKI #ToxCheck #Hematology #OncologyBrothers #PrecisionMedicine
As part of our 2025 Board review course Dr. Fradley reviews some key articles that promise to shape the future of clinical practice.You can purchase the complete set of review course videos at the link below. This includes modules covering the Management & Detection of Cardiac Dysfunction, Toxicities of Traditional Therapies, Hematology, and Immunotherapy.https://members.ic-os.org/store/viewproduct.aspx?id=26378193
Today we're continuing our toxicology mini-series with another group of very common, and often very critical, toxins - human medications. There are a whole host of different medication toxicities we see, and in this episode I'm going to walk you through 4 big ones: paracetamol toxicity in cats, NSAID toxicity in both cats and dogs, inhaler ingestion or overdose, and ingestion of antidepressants and ADHD medications. These patients also need a whole host of nursing support. We're essential in the management of these cases, where prompt triage and stabilisation is vital, as is intensive monitoring. To do that confidently, we need to understand how each of these toxins impact our patients, and the signs we see as a result - so we can spot them, and care for the patient accordingly - and that's exactly what you'll find in this episode. --- BRAND NEW ways to learn with me:
In this conversation, Dr. Sanda Moldovan and Laura Frontiero discuss the challenges many face with chronic health issues despite following a healthy lifestyle. They explore the transition from traditional to functional medicine, the importance of gut health, and the role of toxins in chronic conditions. Laura shares her methodology for healing, success stories from her clients, and emphasizes the need for a comprehensive approach to health that includes detoxification and addressing underlying issues. The conversation concludes with an invitation to Laura's upcoming masterclass aimed at helping individuals break the midlife symptom cycle and regain their health. Want to see more of The Holistic Dentistry Show? Watch our episodes on YouTube! Do you have a mouth- or body-related question for Dr. Sanda? Send her a message on Instagram! Remember, you're not healthy until your mouth is healthy. So take care of it in the most natural way. Key Takeaways: (00:00) Introduction to Health Challenges (04:44)Transitioning from Traditional to Functional Medicine (06:56) Understanding the Methodology of Healing (09:41) Success Stories and Transformations (11:51) The Role of Toxins in Chronic Conditions (12:54) The Importance of Gut Health (16:30) Detoxification: Myths and Realities (18:41) Identifying Symptoms of Toxicity (22:45) Addressing Persistent Health Issues (25:03) Upcoming Masterclass on Midlife Health (26:57) Final Thoughts and Messages of Hope Guest Info: Instagram: https://www.instagram.com/laura.frontiero/?hl=en Live Master Class: Break the Midlife Symptom Cycle! Wednesday, November 12, 2025 at 4pm PT / 7pm ET Sign Up Below! https://breakthemidlifesymptomcycle.com/registration?am_id=sanda8574 Connect With Us: AskDrSanda | YouTube BeverlyHillsDentalHealth.com | Instagram DrSandaMoldovan.com | Instagram Orasana.com | Instagram
Dr. Monty Pal and Dr. Pauline Funchain discuss the latest efforts to diagnose, prevent, and treat the series of immune-related adverse events that have emerged in the era of immunotherapy. TRANSCRIPT Dr. Monty Pal: Hello, and welcome to the ASCO Daily News Podcast. I am Monty Pal, a medical oncologist, professor and vice chair of medical oncology at the City of Hope Comprehensive Cancer Center in Los Angeles, California. Now, it is probably no surprise to this audience that immunotherapy has transformed the treatment landscape for multiple cancer types. It remains a pillar of modern oncology. Having said that, I think we have all been baffled by certain toxicities that we run into in the clinic. Today, I am delighted to be joined by Dr Pauline Funchain to discuss some of the checkpoint inhibitor toxicities that people struggle with most. And we will also touch on some side effects of immunotherapy beyond checkpoint inhibitors: CAR-T cells, bispecifics, so on and so forth. Dr Funchain is a dear friend, and she is an associate professor and associate director of cancer research training and education at the Stanford Cancer Institute. She is co-director of the Immunotherapy Toxicity Program and the Skin Cancer Genomics Program at Stanford, where she also serves as associate program director of hematology and oncology fellowship. Dr. Funchain is also the co-founder of ASPIRE, and we are going to talk about that a little bit today, the Alliance for the Support and Prevention of Immune-Related Events. FYI for listeners, if you are interested in our disclosures, they are available at the transcript of this episode. Pauline, thanks so much for joining us today. Dr. Pauline Funchain: Monty, thank you for this invitation. It is always great to talk. Dr. Monty Pal: So, for the audience, Pauline and I know each other from my days as a fellow at City of Hope. She was a resident at Harbor UCLA and a stellar resident at that. It has just been amazing to sort of see your career grow and blossom and to witness all the cool things that you are doing. ASPIRE, in particular, sort of caught my eye. So again, for listeners, this is the Alliance for the Support and Prevention of Immune-Related Events. Can you tell us a little bit briefly about the genesis of that, how that came about? Dr. Pauline Funchain: So, there was a bunch of us who were really struggling, I mean, all of us have struggled with these immune-related adverse events, these irAEs. You know, they are new disease states, and even though they look like autoimmune diseases, they tend to need a whole lot more steroid than autoimmune diseases do and they do not totally present in the same way. And in fact, you know, Triple-M, or Triple-M overlap syndrome, is a completely new irAE, a new immune state that we have never had before the advent of checkpoint inhibitor. And so a Triple-M, for those of you who are not as familiar, that is the constellation of myocarditis, myositis, and myasthenia gravis, something that never occurs as a natural autoimmune disease. So we were starting to realize that there were some major differences with these irAEs and autoimmune diseases. We could not treat them the right way. We really needed to learn more about them. And a bunch of us who had interest in this said, "Look, we really need to be all in one space to talk about what we are doing," because all of our treatments were our own little homegrown brews, and we needed to really get together and understand how to treat these things, how to diagnose them, and then learn more about them. So, Dr. Alexa Meara from Ohio State, Dr. Kerry Reynolds from Mass Gen, we put together this research consortium, brought together all of our irAE friends, got our best subspecialists together in a research consortium, which is now only about a year and a half old. And we made this research consortium, the Alliance for Support of Prevention of Immune-Related Events, and we reached out to ASCO, and ASCO was so kind to grant us a [Alliance for Support and Prevention of Immune-Related adverse Events (ASPIRE)] Community of Practice. So we met for the first time as a Community of Practice at the ASCO Annual Meeting just this past June and really got an ASCO community together to really think about how to again, diagnose, prevent, treat irAEs. Dr Monty Pal: This is interesting to me. The ASCO Community of Practice phenomenon is something that I was not super familiar with. Can you explain to our listenership what is the ASCO Community of Practice model? If you have particular interests, how do you sort of get one started? Dr Pauline Funchain: Yeah, so ASCO has an entire page on their Community of Practice. There are multiple Community of Practice groups or COPs. There are ones for Supportive Oncology and Survivorship. There is Women in Oncology. There is a group for International Medical Graduates. And there is about, I think 10 or 12 now that have a physical presence at ASCO but also a virtual presence on the ASCO Community of Practice site. So, if you were interested in any one of these, and you can see them on the ASCO Communities of Practice sites, you would ask to become a member. Once granted membership, then there is a whole webpage of postings and conversations that people can have. You can get email digests of conversations that happen on the website, and then you can anchor it with in-person participation at the Annual Meeting. Dr Monty Pal: That is awesome, and I can think of so many different foci within oncology that really sort of deserve a Community of Practice. This definitely being one of them. You know, it strikes me as being so interesting. I mean, the checkpoint inhibitors have been around for a while now. I think when you and I were in training, gosh, back then, these were just a little bit of a pipe dream, right? But having said that, I would probably say that more than half of my kidney cancer practice is either on checkpoint inhibitors, and the vast majority have been on one at some point in their past, right? With that in mind, you know, we have all treated a lot of patients with these drugs. Why is it that we still struggle to manage the toxicities? And just to take that one step further, what are some of the toxicities that, perhaps through ASPIRE or through your experience, people struggle with the most? Dr Pauline Funchain: So, I think we are still struggling with these because again, they are new disease states, right? This is what we all experienced with COVID, a brand-new virus and a brand-new syndrome. We now have 20-plus of these as irAEs. And what we have realized about them is the immune activation that happens with these is so much more than what we have seen with autoimmune diseases. So for instance, if you have a Crohn's or ulcerative colitis, you will top out at 40 to 60 milligrams of prednisone if a Crohn's flare or ulcerative colitis flare happens. But for our severe IR colitises, you know, it is at least 1 mg per kg, often goes up to 2 mg per kg. We, in some cases, have done 1 gram pulses if we are worried that somebody is going to perforate. So that was sort of like the first 5 years of treating irAE, and then now in the sort of second 5 years of treating irAE, we have realized that that is a lot of immunosuppression, and we might be able to get away with less with the newer biologics that are on board. So, we are struggling to try to get the data for some of these irAEs that we knew, we have known for a while, but to try to get newer treatments that may immunosuppress less so that you may still be able to retain that tumor response. And in fact, some of the preclinical studies suggest that some of these biologics may actually synergize with the immunotherapy and actually make the immunotherapy more effective from a tumor perspective and calm down the irAE as sort of the bystander effect. So we are still trying to optimize those. Getting up trials in the space has been very difficult. That is one of the reasons for the genesis of ASPIRE because we realized we needed to band together to have a bigger voice in that realm. Then there are other things that are brand new. So we talked about Triple-M. So Triple-M, again, with Triple-M or any myocarditis or myasthenia, I mean, there is about a 50% chance of death from irAE based on the literature. I think we are getting better at recognizing this, and so at Stanford we have some data to say that if you serially follow troponin, that maybe your outcomes are better. You can potentially lower the percentage of cases that are fatal because you can catch them early. I mean, this is all preliminary data, but again, these are all things that are evolving, and we do not all have the right answer. I mean, even the serial troponin thing, I think, is pretty controversial. And in fact, at one of our quarterly Zoom meetings that we are doing in ASPIRE in December is going to sort of flush out that controversy about serial troponin measuring and what is the best thing to use? Would you use something like abatacept or would you use ruxolitinib? Which one is better? I think there is a lot of controversy still about these things. Dr Monty Pal: You have really piqued my curiosity here because you think about the cons of treating irAEs, right? And I worry exactly about what you had mentioned, right, which is, "Gosh, what is going on with this tumor in terms of immunosuppression?" But you think about some of the newer agents, you mentioned ruxolitinib, I have heard of dasatinib, for instance, in this setting. Frankly speaking, a lot of these, as you point out, are really thought of as being also anticancer drugs. So you have really got me thinking about the potential synergy between perhaps suppressing an irAE and augmenting antitumor activity, which I think is very interesting. Am I on the right track with that? Dr Pauline Funchain: I think so, but you will find that a lot of people will not even go there because they are worried about how much immunosuppression you are going to cause. I am at heart a geneticist, but I think an immunologist will happily tell you that the immune system is very complex. There are multiple pathways, and these drugs do not all target the same immune pathways. So if we understand a little bit more about the pathways we are targeting and pick apart the pathways that are really, really tumor relevant and the other pathways that are not tumor relevant, you may be able to piece together a better marriage of tumor response and irAE control. Dr Monty Pal: Kind of on this topic, and again, leaning on your background in genetics, where are we in terms of predicting these irAEs? I mean, you would think the holy grail would be picking out a snip or something of this for it, right, that could potentially identify that patient who is going to get Triple-M or, you know, at the very least a significant high-grade irAE event. Are we anywhere closer to that in 2025? Dr Pauline Funchain: There have been data published. There have been some big GWAS studies. All of the effect sizes are pretty small. So there are some prediction algorithms, but none of them are clinically useful. And I think when you look at the odds ratios, they will increase risk by maybe 20%. I think one of the things that we found in a very small series and supported anecdotally is something as easy as family history of autoimmune disease is probably more predictive at this point than any of those types of markers. I think we will get there, but we are not anywhere near where we would like to be. Things like TMB also, actually, there is some good data about higher TMB, higher risk of irAE too. Dr Monty Pal: Interesting. I see all this data coming through, IL-8 polymorphisms, etc. And I just wondered if any of that was ready for prime time. But I mean, this is a good message for the practicing clinician. Sounds like we are not quite there yet. And I could probably keep you on for another entire podcast to talk about this topic, but let us see if we can at least skim the surface. I never thought I would see the day when BiTEs and CAR-Ts were entering into my kidney cancer practice, but in fact, it is really become central to a lot of our clinical trials in RCC these days. I would be lying if I did not say that I was not struggling with the toxicities and so forth associated with these drugs. Can you give us a quick primer, maybe just good resources that people can go to for managing toxicity with BiTEs and with CAR and with some of these novel therapeutic modalities that we are using in the oncology clinics? Dr Pauline Funchain: I know there is a recently published toxicity manual for BiTEs in hematologic malignancies, I think it was in Blood. CAR-T is covered in many irAE guidelines. So ASCO guidelines actually has a CAR-T [cell therapy guideline], and I would be remiss not to point out that actually ASCO has a, I am a little biased, but a wonderful guideline on irAE that is actually being updated as we speak. We are hoping for publication next year. I find the format of that, there are many guidelines out there, actually. There is ASCO, SITC, ESMO has a guideline for irAE, but I find the formatting of the ASCO guideline to be much easier to flip through during clinic, just because of the visual format of the tables. But that is going to be updated next year. And with CAR-T, there is now multiple publications also in terms of guidelines. But what I will say about bispecifics and CAR-T, so they have very similar toxicities in terms of the cytokine release and also with the ICANS, so the neurotoxicity. But what we have been finding that is really interesting with BiTEs and CAR-T, and actually even with TIL, cytokine release is very similar to some of the IL-2 toxicities but not identical that we see with TIL treatment. But now we are starting to see overlap. So patients who have been treated with immunotherapy and then go on to get a bispecific or then go on to get TIL, so I have seen some colitises that have occurred after the fact. Some of the newer CAR-Ts without checkpoint have been causing some really interesting, probably not in a good way, but interesting biologically, colitises that are really refractory. So we are starting to see some overlap, and again, I think this field is just evolving constantly. Dr Monty Pal: Yeah, no, I almost think I need to go back to that fellowship that you and I did together 20 years ago and, you know, and see if I could repeat some coursework on CAR-T management. You know, Pauline, I could probably keep you on the horn for hours, but this has just been terrific. Thank you so much for sharing all of your insights with us today on the ASCO Daily News Podcast. Dr Pauline Funchain: Thank you for the invitation. It was wonderful to talk about this, and it was wonderful to catch up a little bit, Monty. Dr Monty Pal: Same here, same here. And thanks to our listeners too. If you value the insights you heard today on the ASCO Daily News Podcast, please rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speakers: Dr. Monty Pal @montypal Dr. Pauline Funchain @FunchainMD Follow ASCO on social media: @ASCO on Twitter ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. Monty Pal: Speakers' Bureau: MJH Life Sciences, IntrisiQ, Peerview Research Funding (Inst.): Exelixis, Merck, Osel, Genentech, Crispr Therapeutics, Adicet Bio, ArsenalBio, Xencor, Miyarsian Pharmaceutical Travel, Accommodations, Expenses: Crispr Therapeutics, Ipsen, Exelixis Dr. Pauline Funchain: Consulting or Advisory Role: Merck, Replimune, Sanofi/Regeneron, Immunocore, Tempus Research Funding (Inst.): Pfizer, Bristol-Myers Squibb, IDEAYA Biosciences, Linnaeus Therapeutics Travel, Accommodations, Expenses: Merck
Fluoropyrimidines such as 5-fluorouracil (5-FU) and capecitabine remain cornerstone chemotherapies in oncology. However, for patients with certain DPYD gene variants, these commonly used drugs can cause life-threatening toxicities due to impaired metabolism of the active compounds. In this episode of the Precision Medicine Pharmacist Podcast, host Melissa Smith, PharmD, explores how DPYD genotyping is transforming oncology care by helping clinicians identify patients at risk before toxicity occurs. Joined by Karen Merritt, an advocate for universal DPD testing and leader with the Test4DPD initiative, the discussion sheds light on how pharmacogenomics is shaping safer, more personalized cancer treatment. Together, they explore current evidence, new FDA updates, and implementation frameworks that empower pharmacists and oncology teams to prevent preventable harm through precision medicine.
On our perpetual quest for bigger, better, faster, wealthier, and stronger, we're led to believe that more is the answer – more gadgets, advanced technology, connections, resources, money, entertainment, etc. But what if there was a case to be made the answer to fulfillment is not in more but in less? My guest today, Dewyane Noel, makes that case. We talk about why less is more, how to reduce noise, chaos, and distraction in the modern world, the value of a hard day's work, what we can learn about human behavior through good horsemanship, and why good men ride good horses. SHOW HIGHLIGHTS 00:00 – Working Together as Men 04:21 – Teaching the Next Generation of Horsemen 07:49 – "He Rode Good Horses" and Life Lessons 09:16 – A Man's Epitaph and Legacy 09:59 – The Purpose Behind Becoming a Better Man 13:09 – Hitting Rock Bottom and Choosing Change 17:19 – Guarding Peace and Avoiding Old Patterns 19:53 – Living Off the Grid and Finding Rest 24:38 – Setting Boundaries and Protecting Privacy 25:39 – Why Dwayne Began Sharing His Message 27:47 – The Best Advice: Just Chill 30:55 – Needing Less vs. Always Wanting More 35:38 – Filtering Needs vs. Wants 42:23 – The Easiest Person to Lie to Is Yourself 43:10 – How a Man Learns to Like Himself 48:51 – Weakness, Horses, and Assertiveness 51:25 – Leadership, Trust, and the Alpha Role 57:24 – Teaching Responsibility Before Autonomy 01:04:10 – Redefining Manhood and Discipline 01:07:30 – Fatherhood, Boundaries, and "Toxicity" 01:12:29 – The Benevolent Alpha in Marriage 01:15:34 – Growth, Maturity, and Becoming a Better Man Battle Planners: Pick yours up today! Order Ryan's new book, The Masculinity Manifesto. For more information on the Iron Council brotherhood. Want maximum health, wealth, relationships, and abundance in your life? Sign up for our free course, 30 Days to Battle Ready
Recently(ish) someone brought a video to my attention from a soil scientist who was talking about the concern with perlite and fluoride toxicity. There were a few issues with the data and the points presented, and while the studies I found that line up with this video do show little cause for concern, they weren't designed with real-world applicability in mind. Listen to the episode for these points as well as what we can do to minimize risk. And, as always, Oh Happy Dirt remains perlite-free because it's my job to make it the absolute best available :) Also, right now (end of October/early November 2025) there's a sale on: spend $50, get a free quart of either V's Mix or our hoya soil. Https://OhHappyPlants.shop
You can't choose your trials, but you can choose your attitude. That is the main message of today's guest, Vanessa Kyrobie, who faced sudden and extreme medical challenges that threatened her life after years of perfect health. While her trials may be very different from the ones you are facing, her profound message may inspire you to see your own life and trials in a different light.Nessa's book: "Gadolinium Deposition and Toxicity" on AmazonHope For Fertility websiteSee Vanessa's pictures on the Just Love Them Facebook page
Let's challenge some stereotypes by dissecting this "10 Harsh Masculine Truths" post and reframing toxic masculinity as an issue of individual character. Through stoic principles, we emphasize humility, resilience, and genuine strength over cynicism or bravado. Shifting to the life in the Dojo, we explore the true meaning of earning a Blackbelt, not as an end goal but as the beginning of lifelong learning, teaching, and humility. We discuss aging as a martial artist and the importance of inclusivity and respect within the community. Finally, we unpack emotional authenticity in men, using the “crayon box” metaphor to encourage a broader range of expression, touching on gaming, comics, and other outlets that reveal how growth and effort define real strength.--------- EPISODE CHAPTERS ---------(0:00:04) - Unpacking Masculine Truths and Toxicity(0:21:33) - Exploring the Meaning of Black Belts(0:35:11) - Defining Masculinity Through Warrior Image(0:53:06) - Navigating Performative Masculinity Challenges(0:58:13) - Navigating Male Coping Mechanisms and EgoSend us a text
We give up on those we profess to love too soon. There is something primordial, something gossamer, to do with the body, to do with first inchoate impressions, which attracts us to one another in the first place. Because relationships often begin in shallow waters. As things start to become serious, the couple traverses depths. It's not easy. And unexpected. Murky, weed-laden, algae-full. The clear eyes and the pellucid surfaces of early days is suddenly overladen with things about each other we don't even recognize. It is difficult to swim through the muck. For it seeps into our pores, into the day-&-night of our lives, into our senses, and suddenly everything which was golden turns murky, overladen with offal. What attracted now repulses. This is when things start collapsing. We completely forget what brought us to each other in the first place. In the old days, when coupledom, marriages, were unending, and meant for forever, this was a phase which was meant to be borne, till it passed - and one learnt to live with it. Often, things remained as they were, however deep the relationship went. Toxicity was the norm. Individually we were supposed to grow, as a couple we were supposed to fly. Instead there was claustrophobia and a sense of doom. But the tragedy often was elsewhere. The tragedy was when we never gave a chance to time and change. Because as one swam through the muck, something magical often started to emerge. Pellucid waters. Depths which captured light like mussels catch pearls. Where the muck was the rough exterior but grace and beauty were permanent residents - albeit hidden. For the couple, there was a sense of transcendence. And since it was reached with patience, forbearance, commitment, there was a sense of gratefulness and wonder which filled us. So, beyond anything and everything, relationships need the patience of space. Time's hard knocks are a phase to build resilience, to understand the other, and more importantly, for us to uncover layers in ourselves we didn't know existed. Discovery and understanding are both the magnet and the glue which holds a couple together. If you liked this poem, consider listening to these other poems on the passages of relationships - Lovers Who Synchronise (and those who don't) Return to You I Said I Love You First Subscribe to my newsletter 'The Uncuts' Follow me on Instagram at @sunilgivesup. Get in touch with me on uncutpoetrynow@gmail.com The details of the music used in this episode are as follows - Satisfaction by Sascha Ende Reaching the sky by Alexander Nakarada Link: https://filmmusic.io/en/song/Satisfaction Link: https://filmmusic.io/en/song/Reaching-the-sky Licence: https://filmmusic.io/standard-license
A2 THE SHOW #584 Our next guest on A2 THE SHOW is Dr. Garrett Smith, known as The Nutrition Detective — the world's leading expert on vitamin A toxicity and detoxification. In this episode, we dive deep into the truth about vitamin D3 and A supplementation, the hidden dangers of food fortification, and how toxicity affects both physical and mental health. Dr. Smith also shares insights on personalized nutrition, detoxing safely, and how modern diets, EMFs, and lifestyle choices shape our long-term wellbeing.
Carl Kinsella, the man behind the column ‘Surrealing in the Years', tells Oliver about his new book ‘At Least It Looks Good From Space: A catalogue of modern, millennial and personal catastrophes'
In this episode of Oncology Brothers, we dived deep into the world of CDK4-6 inhibitors, focusing on their side effects and management in breast cancer treatment. Joined by an esteemed guest, Dr. Stephanie Graff, a medical breast oncologist from Brown University Health. We explored the side effects and management strategies for three commonly used CDK4/6 inhibitors: ribociclib, abemaciclib, and palbociclib. Key topics discussed include: • The evolving role of CDK4/6 inhibitors in early breast cancer and adjuvant settings. • Detailed management of side effects such as QT prolongation, liver function tests, and diarrhea. • The importance of shared decision-making with patients regarding treatment options. • Insights into the latest clinical trial data and its implications for practice. Whether you're a healthcare professional or someone interested in oncology, this episode provides valuable insights into optimizing patient care while managing the complexities of CDK4-6 inhibitors. Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Don't forget to like, subscribe, and check out our other episodes for more discussions on oncology treatments and patient management strategies! #CDK4/6inhibitors #BreastCancer #Ribociclib #Abemaciclib #Palbociclib #OncologyBrothers #SideEffectManagement #HRpositiveBC
In this episode of the “Level Up Claims” podcast, Galen Hair explores the complexities of fire-related insurance claims with Jonathan Bowers, Executive Director of Clean Environmental Solutions. Bowers shares insights on how proper testing and understanding of building science can mitigate risks and enhance safety for property owners after fire events like wildfires. Discover why staying updated on the latest scientific advancements in fire remediation could be a game-changer for your claims strategy. A must-listen for claims professionals seeking growth opportunities! Highlights Importance of understanding fire claims. Growth opportunity in property claims. Toxicity of microparticles in fires. Distinction between urban and wildfire claims. Effective contamination testing methods. Balancing cost and thoroughness in testing. Impact of HVAC systems on fire claims. Knowledge gaps in public adjusters. Testing standards and building science integration. Challenges with content claims in insurance. Episode Resources Connect with Galen M. Hair https://insuranceclaimhq.com hair@hairshunnarah.com https://levelupclaim.com/ Industry Resources: AIHA: https://www.aiha.org/ IICRC Standards: https://webstore.ansi.org/sdo/iicrc Relevant Articles: Article 1: Research Paper Article 2: Fastest Growing and Most Destructive Fires
In this final episode of the No Brainer podcast, hosts Geoff Livingston and Greg Verdino reflect on their journey through the AI industry, discussing the challenges, hype, and potential of AI technology. They express their frustrations with the current state of AI, particularly the influence of companies like OpenAI, and the impact of misinformation on society. The conversation shifts to the positive applications of AI, emphasizing the need for technology to elevate humanity. They also explore the evolving landscape of marketing and content creation in the age of AI, highlighting the importance of quality information and genuine human-to-human engagement. As they sign off, they share their hopes for the future of AI and the need for companies to adopt a more responsible approach to technology. Some Key Takeaways The AI industry is filled with hype and misinformation, with OpenAI's role in feeding the hype machine and their fixation on profit over purpose being particularly problematic. ·AI has the potential to elevate humanity but only if the people and organizations who adopt it focus on solving real-world problems rather than pure productivity and efficiency. The current state of information quality is declining due to AI, with misinformation and disinformation harming the entire information ecosystem – from media to the web to social networks. The nature of content is evolving rapidly due to AI technologies. Creators and companies need to adapt at the speed of change, while maintaining a clear focus on quality, value, engagement, and human connection. Chapters 00:00 Introduction and Farewell to the Podcast 02:42 Reflections on the AI Industry 05:14 Critique of AI Hype and Influencer Culture 08:03 The Dark Side of AI: OpenAI and Its Impact 10:55 Positive Aspects of Generative AI 13:39 The Future of Work and AI's Role 16:20 The Changing Landscape of Content Creation 22:18 The Toxicity of the Information Ecosystem 27:37 The Challenges of Digital Marketing 37:04 The Future of AI and Humanity Learn more about your ad choices. Visit megaphone.fm/adchoices
October is Breast Cancer Awareness Month, and we're spotlighting a critical—but often overlooked—piece of the journey: financial toxicity. Katana welcomes Molly MacDonald, co-founder & CEO of The Pink Fund and Editor-in-Chief of Breast Cancer Wellness Magazine.After her own diagnosis upended her livelihood, Molly built a national nonprofit that has paid nearly $11 million in non-medical bills for patients in active treatment—housing, transportation, utilities, and insurance—so they can stay on therapy and focus on healing.We also explore the magazine's mission to educate, inspire, and deliver hope; the SurThrivor™ mindset; and community-powered fundraising like Dancing with the Survivors. You'll learn:What “financial toxicity” looks like—and practical ways to prevent treatment disruptionHow The Pink Fund's 90-day “financial bridge” works (what's covered & who qualifies)Why education and mindset (via Breast Cancer Wellness Magazine) are essential to survivorshipResources & links:The Pink Fund (apply, donate, become an ambassador): https://pinkfund.orgSubscribe free to Breast Cancer Wellness Magazine: https://pinkfund.org
This is a fan fav episode. The term narcissist gets thrown around a lot to the misfortune of people who are not actually narcissistic. Toxicity, emotional, mental, and verbal abuse are clear common markers of narcissistic behavior. Hopefully, you're not in a relationship with a narcissistic person, but perhaps you've recently left a toxic situation and still feel lost, confused and uncertain how to handle the narcissist in your life. Dr. Ramani doesn't mince words when it comes to dealing with narcissists. The depth of knowledge she has from working with victims of narcissism is mind-blowing. In this episode we've packed some of the best advice Dr. Ramani has shared with Lisa on Women of Impact so you can take notes and the cycle of abuse and start healing. If you've managed to avoid relationships with narcissists to this point, we're cheering for you. We want you to be safe and be aware of the red fags many people miss until it's too far gone. SHOW NOTES: 0:00 | Introduction to Dr. Ramani 0:09 | Look for These Red Flags 26:02 | They Weaponize Vulnerabilities 47:48 | 6 Types of Narcissists 1:04:44 | Red Flags in Conversation 1:15:15 | How to Heal & Detox 1:37:06 | Break the Trauma Bond 1:52:15 | How to Leave a Narcissist Original air date: 5-15-2022 Follow Dr. Ramani: Website: http://doctor-ramani.com/ YouTube: https://www.youtube.com/user/DoctorRamanDurvasula Twitter: https://twitter.com/DoctorRamani Instagram: https://www.instagram.com/doctorramani/ Facebook: https://www.facebook.com/doctorramani Learn more about your ad choices. Visit megaphone.fm/adchoices
We tend to imagine our own club is utopian compared to the others you hear about on social media where bad things happen. I'm here to let you know that every club is fertile ground for toxic behaviour. But what can we do about it?
Join us for another taste of the Straight Dope Show, where we dive deep into the world of sports, culture, and the absurdities of everyday life! In these clips fomepisode 313 and 314, we tackle the heated dynamics between players and referees, dissecting the ongoing drama surrounding Chris Paul and the implications of sensitivity in competitive sports. We also share hilarious anecdotes, including a wild encounter with counterfeit cash that highlights the lengths some will go to in their attempts to get over. With our signature blend of humor and insight, this episode promises to keep you entertained and engaged. Don't miss out—tune in now![00:01:40] Referees' sensitivity in sports.[00:05:16] Referee-player relationships and conflicts.[00:09:36] Criticism of Steve Kerr's coaching.[00:14:40] Streaming numbers and authenticity.[00:15:16] Realness of Sacramento versus Bay.[00:22:40] Lies and unfortunate situations.[00:23:36] Toxicity and consequences in life.Watch new episodes of The Straight Dope Show on RockDaCrowdTV.com or download the Rock Da Crowd TV app on a device near you or watch the episodes featured here on https://www.youtube.com/@thestraightdopeshow
On their weekly Penn State football podcast, host Adam Bittner and Post-Gazette/Daily Collegian Nittany Lions insider Isaiah Maldonado evaluate the state of the program after a costly upset loss at UCLA. Is there anything coach James Franklin can do to escape the toxicity surrounding his job? Does his future deserve to be in question given the elevated commitments the Penn State community has made to the program in recent years? Was Jim Knowles the right hire at defensive coordinator? Or would Dani Dennis-Sutton and the defense have been better off with some continuity in the form of a position coach like Anthony Poindexter? And how much belief genuinely exists in the Penn State locker room after Drew Allar's confident statements that the team can still make the College Football Playoff? Our duo tackles those questions and more. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
We have arrived at the penultimate (main feed) episode of Indexed. Included in this episode is also our last "in studio guest" (TBD?). Any of the weird editing is because of @benjaminpierce2, so blame him
WWW.ADVENTUREFREAKSSS.COM Find your Ideal Destination Here:https://adventurefreaksss.com/ideal-destination-finder/================================= How to work with me: =================================
Financial Toxicities in Breast Cancer: How Costs Impact Treatment Decisions with guest Dr. Rachel Greenup October 5, 2025 Yale Cancer Center visit: https://www.yalecancercenter.org email: canceranswers@yale.edu call: 203-785-4095
“I think that this is an area that is exploding. Working with drug development, I see new agents all the time, with unique targets I've never heard about, with targets I have heard about used in a different way. So, I really think we're going to see more and more bispecifics. A lot of these drugs are used second line, third line, fourth line. I would not be surprised if they moved up in treatment, especially as we learn safer ways to give these drugs,” ONS member Moe Schwartz, PharmD, BCOP, FHOP, professor of pharmacy practice at the James L. Winkle College of Pharmacy at the University of Cincinnati, OH, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about bispecific antibodies. Music Credit: “Fireflies and Stardust” by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0 Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by October 3, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learner will report an increase in knowledge related to the use of bispecific antibodies in the treatment of cancer. Episode Notes Complete this evaluation for free NCPD. ONS Podcast™ episodes: Pharmacology 101 series Episode 275: Bispecific Monoclonal Antibodies in Hematologic Cancers and Solid Tumors Episode 261: CAR T-Cell Therapy for Hematologic Malignancies Requires Education and Navigation Episode 176: Oncologic Emergencies: Cytokine Release Syndrome ONS Voice articles: An Oncology Nurse's Guide to Bispecific Antibodies Bispecific Antibodies Cross-Discipline Cancer Care ONS Voice oncology drug reference sheets: Amivantamab-Vmjw Blinatumomab Epcoritamab-Bysp Glofitamab-Gxbm Mosunetuzumab-Axgb Tebentafusp-Tebn Teclistamab-Cqyv ONS book: Guide to Cancer Immunotherapy (second edition) ONS course: ONS/ONCC® Chemotherapy Immunotherapy Certificate™ Clinical Journal of Oncology Nursing article: Optimizing Transitions of Care in Multiple Myeloma Immunotherapy: Nurse Roles Other ONS resources: Bispecific Antibodies Video Bispecifics Huddle Card Cytokine Release Syndrome Huddle Card Immune Effector Cell–Associated Neurotoxicity Syndrome Huddle Card DailyMed homepage Hematology/Oncology Pharmacy Association late-breaking news article: The Emerging Use of Bispecific Antibodies with Chemotherapy in Diffuse Large B-Cell Lymphoma To discuss the information in this episode with other oncology nurses, visit the ONS communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org Highlights From This Episode “It was 2014 that most of us think of as the beginning of bispecifics in cancer, and that was with approval of blinatumomab. That was granted accelerated approval for the treatment of patients with Philadelphia chromosome–negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia. It is a bispecific that targets CD19-expressing tumor cells and CD3 on T cells. It's the original bispecific T-cell engager and is often called a ‘BiTE.'” TS 2:11 “The term ‘bispecific' means that this is an artificial protein that's developed to hit two different antigens simultaneously. They can be two different epitopes on the same antigen. They can be an antigen on a cancer cell and CD3 on a T cell that kind of recruits the T cell to the cancer. So, there are different types [of bispecific antibodies]. The subtype that we often talk about are bispecific T-cell engagers, which are those bispecifics that do target the T cell. And currently, the target on the T cell that's utilized is the CD3 molecule. That's not the only one that will be used in the future because there's a lot of work being done on other types of T-cell engagers.” TS 4:21 “The targets for lymphoma are CD20. Those are bispecific T-cell engagers that hit CD20 on the lymphoma cell, as well as CD3 on a T cell. ... In myeloma, we have two different targets that have been utilized. One is BCMA or B-cell maturation antigen. That sits on the surface of myeloma cells and on some healthy B cells. ... There's also a target used in myeloma that's called GPRC5D, which stands for G protein–coupled receptor, class C, group 5, member D. ... In small cell lung cancer, there's delta-like ligand 3 (DLL3); it's part of the NOTCH pathway. ... And then this year, we've had a couple agents come out that target HER2.” TS 6:52 “[Toxicities] are very dependent on what your target is. ... The bispecific T-cell engager that's used in myeloma that targets the GPRC5D is also expressed on tissues that produce hard keratin like hair follicles and actually, within the tongue. So the toxicities that we see with that agent are something you wouldn't expect to see if you were using a myeloma agent. You see nail and skin issues. You see taste problems. So it's very specific about the target, which says to me, that every time a new one of these agents comes out, I have to learn about the target that helps me learn about the toxicity. I find that fascinating and really appreciate that.” TS 16:19 “Cytokine release syndrome has been one of the areas that drug development has really focused on to see how they can help mitigate the severity [of it]. ... [One of] the strategies that has been incorporated and studied in clinical trials is the step-up dosing scheme. [It's] where you give initial small doses and over time, increase the dose to the dose you're going to continue with. Usually, monitoring in the hospital is required by the FDA approval for anywhere from 28–48 hours for the first couple of doses. And that's a real common strategy that you'll see. Premedication with H2 blockers, H1 blockers, sometimes steroids. These are also things that are incorporated within the approvals of these drugs and are important to look at.” TS 20:53
Dr. Rahul Banerjee interviews Dr. Ajay Major on patient-reported outcomes, toxicity reporting, and patient engagement in blood cancer clinical trials.
In recognition of World Mental Health Day, we present a powerful and timely conversation with our returning special guest, Beverly Beuermann-King, a seasoned expert in workplace mental health. Beverly shares her insights on two critical threats to workplace safety and well-being today: toxicity in the workplace and the importance of self-care for leaders. She explores real examples of toxic workplaces and offers actionable strategies to help leaders recognize warning signs, communicate effectively, and engage in difficult conversations to address issues head-on. Beverly also unpacks the deeper drivers behind workaholism, sharing how leaders can identify root causes, set healthy boundaries, and intentionally create space to rest, recharge, and reflect, prioritizing self-care to enhance both their own well-being and that of their teams. This episode highlights why mental health isn't just a personal wellness matter; it's a workplace safety issue that fosters a healthier, more resilient workplace culture. Tune in for expert insights to help leaders prevent burnout, navigate toxicity in the workplace, and build environments where people and organizations can truly thrive. About the Guest: Beverly Beuermann-King has over 25 years of experience helping individuals and organizations master their responses to stress, build resilience, and thrive using her innovative S-O-S Principle™. Since founding WorkSmartLiveSmart.com in 1995, she has transformed teams across diverse business sectors. Her presentations, grounded in psychology, sociology, management, and adult education, offer practical strategies to enhance mental health and workplace well-being. She is also a prolific author, respected podcaster, and trusted media spokesperson, with over 500 television and radio appearances. Beverly currently serves as the National President of the Canadian Association of Professional Speakers. Prepare to be captivated as she empowers you to conquer stress, cultivate resilience, and unlock the secrets to a healthier, more fulfilling life. For more information: www.WorkSmartLiveSmart.com Learn more about your ad choices. Visit megaphone.fm/adchoices
Transform your approach to CLL care with insights from clinical pharmacy expert, "Kelsey Marciano, PharmD, BCOP,UCHealth. This podcast unpacks the latest strategies for treatment selection and toxicity management—empowering oncology pharmacists to lead confidently, maximize patient outcomes, and deliver next-level care in the evolving era of oral targeted therapies.
Joshua Ryle brings over two decades of corrections experience to this deeply insightful conversation about the hidden psychological patterns that shape corrections culture. From his early days at the Tennessee Department of Corrections to his current role as a training sergeant, Ryle has observed firsthand how the corrections environment creates behavioral patterns that affect officers both professionally and personally.At the heart of this episode is Ryle's new training program focused on workplace toxicity in corrections. He explains how officers spend their entire workday in a hypervigilant, fight-or-flight state that gradually transforms how they interact with everyone around them. This physiological reality leads to communication challenges, negative filtering, and self-sabotaging behaviors that follow officers home and contribute to concerning wellness statistics in the corrections profession.What makes Ryle's approach unique is his focus on behavioral science and practical solutions. Rather than simply identifying problems, he provides clear strategies for shifting from self-criticism to self-reflection, improving communication despite technological limitations, and creating a culture where colleagues support rather than undermine each other. Ryle's program has gained such recognition that it's now being implemented nationwide through ARC Tactical.Whether you work in corrections or are interested in workplace culture transformation, this episode provides valuable insights into how awareness and intentional behavior change can create healthier environments in even the most challenging professions. Connect with Josh at josh@arttechnet.com to learn more about bringing this training to your agency.Josh's E-mail: josh@arctac.netJosh's phone: 931-624-4444ARC Tactical website: https://www.arctac.net/Send us a text PepperBallFrom crowd control to cell extractions, the PepperBall system is the safe, non-lethal option.OMNIOMNI is cutting-edge software designed to track inmates and assets within your prison or jail. Command PresenceBringing prisons and jails the training they deserve!Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showAlso, check out Michael's newest book - POWER SKILLS: Emotional Intelligence and Soft Skills for Correctional Officers, First Responders, and Beyond https://amzn.to/4mBeog5 See Michael's newest Children's Books here: www.CantrellWrites.com Support the show ======================= Contact me: mike@theprisonofficer.com Buy Me a Cup of Coffee https://www.buymeacoffee.com/mikeml Keys to Your New Career: Information and Guidance to Get Hired and Be Successful as a Correctional or Detention Officer https://amzn.to/4g0mSLw Finding Your Purpose: Crafting a Personal Vision Statement to Guide Your Life and Career https://amzn.to/3HV4dUG Take care of each other and Be Safe behind those walls and fences! #prisonofficerpodcast #leadership #podcast @theprisonofficerpodcast Contact us: mike@theprisonofficer.comFacebook: https://www.facebook.com/ThePrisonOfficerTake care of each other and Be Safe behind those walls and fences!
juniorziegler.com Scripture Reference: 1 Peter 2:13-25
Ever wondered what really happens behind closed boardroom doors when leaders are faced with uncomfortable truths, especially when speaking up could cost them their job? This conversation isn't just about corporate buzzwords or performative change. It's an unfiltered look at how fear quietly shapes decisions, and how a handful of micro-courage moments can actually flip the script for whole organizations. If you think courage at work is all about bold speeches, think again. There's a twist here that might just change the way you see your own leadership, and what's possible for your team. Ready to find out what most leaders are missing (and why it matters now more than ever)? In this episode, you will be able to: Discover how cultivating courage in the workplace can unlock bold decisions that drive real growth and innovation. Learn strategies to overcome fear in leadership that empower you to lead with confidence and authenticity. Build people-first cultures that inspire loyalty, boost morale, and create teams ready to tackle any challenge. Master emotional intelligence and respectful communication to transform workplace relationships and fuel collaboration. My special guests are Kristen Kavanaugh, Mike Randolph Kristen Kavanaugh brings a wealth of real-world leadership experience shaped by roles that truly matter, from her time as Senior Director of Inclusion, Talent, and Learning at Tesla to her service as a Naval Academy graduate and veteran. As Founder and CEO of The Agency Initiative, Kristen focuses on helping leaders and organizations step up with courage, not just when it's easy, but when the pressure is on and the stakes are high. She's also served as Vice Chair for the Department of Defense's first-ever Advisory Committee on Diversity and Inclusion, showing her commitment to building workplaces where everyone can thrive. Mike Randolph is the Co-Founder and COO of The Agency Initiative and a strategic leader with expertise in operational effectiveness and holistic people development. Most recently, Mike held a senior position at YETI, leading and designing Talent Experience programs. Prior to that, he led the Talent Management and Leadership Development organizations at Tesla where he integrated courageous leadership practices into the people systems and programs that accelerated growth. The key moments in this episode are:00:05:17 - Understanding Fear in Leadership and Organizational Culture 00:07:04 - Fear-Based vs Courageous Leadership: Lessons from Tesla 00:10:05 - The Impact of Fear-Based Leadership on Organizations and Society 00:13:11 - The Normalization of Fear and Surveillance in the Workplace 00:15:53 - Leadership Examples Challenging Toxic Normalization 00:17:17 - The Business Case for Protecting Rights and Embracing Diversity 00:19:11 - Leading with Empathy during Crisis and Uncertainty 00:23:02 - The Agency Loop: Courage as the Fuel for Authentic Leadership 00:25:55 - Cultivating Agency, Authenticity, and Growth in Leadership 00:28:00 - Building Courage and Resilience in High-Speed Environments 00:31:00 - Listening to Understand: A Foundation for Authentic DEI Efforts 00:33:00 - Addressing Burnout and Learning Agility in Today's Workforce 00:35:00 - Embracing Curiosity and Courage to Drive Inclusive Leadership 00:38:42 - The Importance of Diverse Leadership Reflecting Customer Needs 00:40:29 - Navigating Cultural Differences and Building Peace at Tesla 00:42:18 - Anchoring Leadership in a Shared Mission to Overcome Conflict 00:44:08 - Courageous Leadership Amid Fear and Toxicity in the Workplace Connect with Kristen Kavanaugh and Mike Randolph Follow on Instagram at @courageoverfearbook, @mikerandolph.official, and @kristenkavanaugh.official for updates and community engagement. Purchase the book at courageoverfearbook.com Learn more about your ad choices. Visit megaphone.fm/adchoices
What dose and mode of ingestion of B12 do you recommend for an active 78-year-old husband and wife?If ubiquinol is more bioavailable than CoQ10, what about other supplements with respect to bioavailability?Does proline help ligaments?What are your thoughts on smart watches and EMF exposure?
We're living longer thanks to medical advancesStudy: Does cannabis use increase the risk of diabetes?What dose of selenium and iodine should I take?What do you suggest for people who have carpal tunnel syndrome? I would like to avoid surgeryWhat do you think of the claims made for EDTA? Are there benefits?I have the beginnings of macular degeneration. Is taking the AREDs supplement helpful?
We discuss propofol infusion syndrome (PRIS) and propylene glycol toxicity from lorazepam infusions, with medical toxicologist Dr. Jerry Snow, director of the toxicology fellowship at Banner University Medical Center in Phoenix. Learn more at the Intensive Care Academy! Takeaway lessons
Today we're doing a deep dive into RHOC, where Tamara brought of the ancient drama of Naked Wasted at a lie decector party. We went back and refreshed our memories by watching Naked Wasted (Season 4, Episode 8 if you'd like to do the same) and we have some THOUGHTS! After we explore the toxicity of RHOC we'll dip our toes into the palette cleanser of Real Housewives of Miami and recap our thoughts on their trip to Seville. Plus: Unknown Number, why Bravo is more enjoyable now that we're sober, and our personal experiences with ADHD and OCD minds. Are you craving community in sobriety? Join us in The Sober Mom Life Cafe! You'll get access to 4 weekly peer support meetings, the exclusive Cafe social feed, our monthly book club, the chance to share your story on The Real Sober Moms, and more! Get one week free at this link! The Sober Shift is now available for pre-order! Pre-order now for three free mocktail recipes and access to my pre-order launch Zoom in October. Plus, take a look at my events calendar for a book tour stop near you. I would LOVE to meet you and thank you for being a part of this incredible community! We have two spots open for The Sober Mom Life retreat Oct 23-26th in Scottsdale, AZ! Join us for an incredible sober getaway!https://www.instagram.com/thesobermomlife/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
What do the acronyms ConVENTID, VENTID and ASS all have in common? Well, have a listen and find out as the boys continue their journey down Highway O2 while avoiding the pitfalls of oxygen Toxicity. Have A Listen!!
The Dad Edge Podcast (formerly The Good Dad Project Podcast)
In this special father-son episode of the Dad Edge Podcast, I sit down with my 19-year-old son, Ethan Hagner, to talk about the ever-evolving world of modern dating, masculinity, and what respect looks like in today's culture. From Snapchat and Bitmoji “vibes” to the dangers of digital footprints, Ethan pulls back the curtain on what Gen Z is really experiencing when it comes to relationships, identity, and self-worth. We get raw and real about breakups, social media drama, posting for “social therapy,” and what red flags look like in 2025. But the conversation goes much deeper than dating. Ethan opens up about his personal growth, past mistakes, and what he'd tell his 16-year-old self—and future daughter—about how to protect your integrity in the world of online relationships and viral opinions. This is a must-listen for any dad raising teens or preteens. It's funny, eye-opening, brutally honest, and packed with generational wisdom from both sides of the table. TIMELINE SUMMARY [0:00] - Welcome to the Dad Edge mission [1:04] - How dating has changed since “back in the day” [2:38] - Meet Ethan Hagner: college, EMT prep, and dad banter [3:58] - Inside the Dad Edge studio & sponsor shoutout (First Form) [5:36] - Ignition + Formula 1 explained: post-workout must-haves [8:08] - Pre-order info: The Pursuit of Legendary Fatherhood [9:11] - How 19-year-olds actually meet people now (Snapchat!) [10:20] - Snapchat's “Quick Add” and Bitmoji-deep dating decisions [14:04] - Dating vs. passing notes in the 90s, how we used to ask friends to “talk to her for me” [16:06] - Red flags on social profiles: vaping, weed, or weird vibes [20:30] - Toxicity, trust, and “the feeling you just can't explain” [24:30] - Social media therapy: breakups that go viral [27:03] - Digital drama and public TikTok crying [30:27] - The real meaning of “game” for Gen Z (hint: not confidence) [32:02] - Confidence vs. bravado: what women really respond to [34:09] - What healthy confidence looks like in teens [35:30] - Are ICks ruining relationships before they start? [39:22] - Ego, lifting, and growing up with the wrong friend group [41:13] - Self-awareness: from wife beater tanks to regretful beliefs [42:35] - Advice Ethan would give his future 16-year-old daughter [43:10] - Digital safety, values, and protecting your future [46:40] - Larry's top two dating lessons for his younger self [47:40] - Regret from not approaching vs. regret from rejection [48:16] - When you strike out, you're still winning [51:11] - Protecting your reputation on social media [52:22] - First Form Dad of the Month: Ty Twizzler's inspiring story 5 KEY TAKEAWAYS 1. Snapchat Changed Dating Forever For Gen Z, Snapchat is the new hallway, lunch table, and dating app combined. But what happens there leaves a permanent digital trail—so teach your kids to tread carefully. 2. Confidence Wins—Ego Repels Bravado might grab attention, but real confidence comes from knowing who you are and not bending for validation. It's quiet, steady, and deeply attractive. 3. Respect Is Never Outdated Whether it's how you treat a teacher, a girlfriend, or yourself, respect is foundational. True character shows when no one's watching—or when everyone's watching online. 4. Your Digital Footprint Never Goes Away Posting relationship drama on TikTok or Snapchat may feel therapeutic in the moment, but it can damage reputations, create enemies, and attract the wrong kind of attention. 5. You're Not Too Young to Lead Ethan may be 19, but his mindset about dating, identity, and future family is already grounded in wisdom. His generation needs more examples like this—and so do ours. LINKS & RESOURCES
© 2020-2025 Ivy Podcast Discovery LLC
