The ability of a chemical to cause damage to life
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Self-care podcast exploring Dangers of Breast Implant Toxicity, Mineral Health and Metabolism & Tips to Improve Mineral Function with Michele Scarlet TOPICS:: ** Dangers of Breast Implant Toxicity (09:39). ** Mineral Health and Metabolism (21:36). ** Tips to Improve Mineral Function (35:37). NOTES:: Show notes: amberapproved.ca/podcast/670 Leave me a review at amberapproved.ca/review Email me at info@amberapproved.ca Take the NEW Free Hormone Imbalance Quiz here: https://amberapproved.ca/hormone-imbalance-quiz Subscribe to newsletter: https://amber-romaniuk.mykajabi.com/newsletter-sign-up SHOW LINKS: Click below to schedule a 30 minute Complimentary Body Freedom Consultation https://amberapproved.ca/body-freedom-consultation/ Take my free Emotional Eating Quiz here: http://amberapproved.ca/emotional-eating-quiz Listen to Episode 291 about what it's like to work with me here: http://amberapproved.ca/podcast/291/ Follow me on Instagram www.instagram.com/amberromaniuk Youtube Channel: https://www.youtube.com/@amberromaniuk/ ABOUT MY GUEST: Michele Scarlet is a Board-Certified Functional Medicine Practitioner, Functional Diagnostic Nutrition Practitioner, Certified Personal Trainer, and Women's Health Coach. Podcast = https://open.spotify.com/show/73cw7w6STS3uNyOmB5IyfK Instagram = https://www.instagram.com/michelescarlet_/ Website = https://www.michelescarlet.com/ MY PARTNERS: Designs For Health Blood Sugar Bundle! One of the hardest parts of overcoming my emotional eating was the INSANE SUGAR and carb cravings. It was the intense sugar and carb cravings. That's why I created my Blood Sugar Bundle with Designs for Health to support your body while you work on emotional eating and breaking binge patterns. It includes chromium for blood sugar balance, L-glutamine to help curb cravings fast, a high-quality probiotic for gut health, and a clean Pure Paleo protein powder to keep you full and stable. I only recommend Designs for Health to my clients because they are third-party tested, family-owned, and use the highest quality ingredients. Quality matters when it comes to truly supporting your body and getting results. Get 30% off The Blood Sugar Bundle in USA and Canada automatically applied at checkout below! Canada Blood Sugar Bundle here for 30% off! USA Blood Sugar Bundle here for 30% off! You can also get 30% off any Designs for Health supplements anytime, it's my gift to you. Canada: www.designsforhealth.ca (code AMBER30) USA: www.designsforhealth.com (code AMBER88)
On today's Good Day Health Show - ON DEMAND…Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) cover a number of topics affecting our health. First up, Doug and Dr. Ken explore the latest research on nutrition, lifestyle choices, and disease prevention. The conversation begins with a look at the effects of marijuana on vascular function and heart health, examining what emerging studies reveal about its potential impact on the cardiovascular system. Dr. Ken also discusses the powerful connection between healthy dietary patterns in midlife and long-term brain health, highlighting how nutrition can play a key role in supporting cognitive function and healthy aging.The discussion continues with an examination of soil quality and its influence on the nutrient content of the foods we eat, emphasizing the importance of healthy agricultural practices in supporting human health. Dr. Ken also addresses concerns surrounding herbal supplements, including the potential risks some products may pose to liver health and why consumers should carefully evaluate supplement choices. Rounding out the episode is a conversation about weight loss and the significant long-term health benefits that can result from even modest reductions in body weight. Packed with practical insights and evidence-based guidance, this episode offers listeners valuable information for making informed decisions about their health and well-being.For more on Good Day Health…Website: GoodDayHealthShow.comSocial Media: @GoodDayNetworks
No change, means you get the same results, which falls solely on you! Most people blame but who you become falls on you! Whatever reason you choose not change keeps you bind and bound up with the same unhealed mindset, thinking, feeling, and acting the same! Most peope have lived dysfunctionally for so long until they've deceived themselves. The abnormal is normal to them!You can listen to this Podcast on Amazon and Spotify! Become a supporter of this podcast: https://www.spreaker.com/podcast/relationships-and-relatable-life-chronicles--4126439/support.
We welcome Dr. Julia Ponder, the Director Emeritus of The Raptor Center, back to the show to discuss lead toxicity, particularly in bald eagles. In this episode, we explore the differences between acute and chronic toxicity, the range of clinical signs associated with each, methods used to diagnose, ongoing education and outreach efforts, and common sources of exposure. In part two, we'll take a closer look at treatment and care.Special thanks to our guests, Partners For Wildlife, and The Raptor Center at the University of Minnesota College of Veterinary Medicine.Resources mentioned:Demographic implications of lead poisoning for eagles across North AmericaThe Raptor Center Research on Lead ToxicitySporting Lead FreeUSFWS lead free initiativeLead Free PartnershipGo Lead Free for WildlifeExamining the effect of the Hunter's Choice: Alternative Ammunition project on Minnesota deer hunters' knowledge, attitudes, behavioral intentions, and behaviors regarding lead ammunition
In this episode of TOGA's Conversations in Lung Cancer Research, host A/Prof Rachel Roberts-Thomson, a Medical Oncologist at The Queen Elizabeth Hospital and Cancer Care Adelaide, leads a panel discussion focusing on the landscape of BRAF-mutated non-small cell lung cancer. Joined by Prof Ahn Myung-ju, a Medical Oncologist at Hanyang University Medical Centre in South Korea as well as Co-chair for the upcoming World Lung Cancer Conference, and A/Prof Adnan Nagrial, a Medical Oncologist at Westmead Hospital in Sydney. The panel discusses the clinical characteristics and incidence of this molecular subset, the critical need for upfront comprehensive genomic testing, key clinical trial data for targeted therapies, and practical strategies for managing treatment-specific side effects like pyrexia syndrome. This episode is sponsored by Pierre Fabre. (00:00) Welcome and Acknowledgement (00:47) Introducing the Topic and Panel (01:56) BRAF Incidence Overview (02:43) Testing Pathways in Australia (06:16) Mutation Classes and Tools (07:47) Korea Testing Perspective (09:03) Pivotal Targeted Therapy Trials (13:33) Choosing First Line Treatment (16:40) Australian Sequencing Approach (20:23) Managing Pyrexia and Toxicities (25:49) Wrap Up Support TOGAThank you for listening to Conversations in Lung Cancer Research. If you enjoyed this episode, please rate and review us on Apple Podcasts or Spotify.---------------Connect with TOGAAttend an Event: https://thoraciconcology.org.au/events/Become a Member: Join the TOGA community at https://thoraciconcology.org.au/membership/Donate: Support our research and treatment initiatives at https://thoraciconcology.org.au/support-us/donate/Follow UsLinkedIn: https://www.linkedin.com/company/thoracic-oncology-group-of-australasia/X (Twitter): https://x.com/TOGAANZInstagram: https://www.instagram.com/togaanz/YouTube: https://www.youtube.com/@Thoracic_Oncology---------------Acknowledgement of CountryThe Thoracic Oncology Group of Australasia Limited acknowledges Traditional Owners of Country throughout Australia and recognises the continuing connection to lands, waters and communities. We pay our respect to Aboriginal and Torres Strait cultures; and to Elders past and present.
Toxicities related to antibody-drug conjugates (ADCs) can significantly impact quality of life for patients with locally advanced or metastatic bladder cancer, but data-driven programs can help multidisciplinary teams manage some of the most challenging adverse events. In this episode, CANCER BUZZ speaks with Cindy Y. Jiang, MD, assistant professor at MD Anderson Cancer Center, about how her institution conducted and implemented research to aid management of rashes and peripheral neuropathy associated with the ADC enfortumab vedotin combined with pembrolizumab. Guest: Cindy Y. Jiang, MD Assistant Professor Department of GU Medical Oncology MD Anderson Cancer Center Houston, TX "It's important to assemble this team before you start on any sort of journey, because as oncologists, we're definitely not experts in skin rashes or neurological issues, and so you really need to rely heavily on those collaborators." — Cindy Y. Jiang, MD Resources: Bladder Cancer Antibody-Drug Conjugates
Mike tackles the growing hostility and division shaping America’s political landscape, examining why so many voters feel the tension heading into another pivotal election cycle. From media firestorms and controversial political prosecutions to calls from prominent voices on the left to “de-MAGA” the country, Mike argues that the battle is no longer just about policy—it’s about competing visions for America’s future. He contrasts the pessimism and outrage dominating much of today’s political discourse with a message of optimism, patriotism, and civic engagement, while highlighting the importance of voting, protecting free speech, and preserving ideological diversity. Along the way, he discusses the case of Tina Peters, turmoil at major media outlets, the fight over ICE enforcement, and why he believes happiness, faith, and confidence in America remain the strongest antidotes to today’s toxic political climate.See omnystudio.com/listener for privacy information.
What to listen for:"If you are not doing search and rescue for the right reasons, you need to look in the mirror. Because it is not about you, and it's not about your dog."Today, our hosts, Stacy Barnett and Robin Greubel, have set the dogs aside (mostly!) to talk about something that affects every handler who has ever posted a training video, shown up to a webinar, or scrolled too far down a comment thread. They're calling it the “toxicity tax,” and they've come to argue it's being paid at every level of the canine world, from nose work titling to search and rescue callouts.The online world, particularly on social media, strips away tone, facial expression, and social consequence, leaving text that people read with whatever emotional state they're already carrying.Robin references the book Don't Feed the Elephants! when she explains that “Avoidaphants” are everywhere in teams that have never sat down to agree on how they want to communicate.Stacy offers sport as a mirror for SAR. The moment you start watching other dogs instead of your own, you've already lost the run. Comparing your dog's time, your team's reputation, your cert against someone else's is a fast road to a distracted, ineffective search.The mission has to be bigger than the handler.Robin and Stacy agree that training is not a recipe. Dogs are individuals, methodology debates serve nobody, and a perfect run every time is evidence of stagnation.What serves the dog, and the missing person, is efficient, effective teamwork built inside a culture that gives grace when the wheels come off. Key Topics:● Why We Eat Our Own: Social Media in the Canine Community (02:40)● Staying Humble, Hungry, and Smart (08:32)● Why Watching Other Dogs Costs You Your Own (15:29)● Posting Mistakes: Safe Groups vs. the Public Feed (24:25)● Principles Over Methodology (32:59)● Constructive Feedback vs. Criticism (37:28)● Coaching Someone Who's a Hot Mess (41:49)● Protecting the Volunteer Pipeline (46:30) Resources:· Don't Feed the Elephants: Overcoming the Art of Avoidance to Build Powerful Partnerships https://amzn.to/4wFYFlk (affiliate link)· Be the Ideal Team Player: How to Recognize and Cultivate The Three Essential Virtues https://amzn.to/4tJq8jq (affiliate link)We want to hear from you:Check out the K9 Detection Collaborative FB page and comment on the episode post!K9Sensus Detection Dog Trainer AcademyK9Sensus Foundation can be found on Facebook and Instagram. We have a Trainer's Group on Facebook!Scentsabilities Nosework is also on Facebook. Here is a Facebook group you should join!You can follow us for notifications of upcoming episodes, find us at k9detectioncollaborative.com to enjoy the freebies, and tell your friends so you can keep the conversations going.And don't forget to check out the YouTube Channel!
Click to Send us a text!Burnout isn't the moment you finally feel exhausted. It's the slow leak that starts while you're still “fine” and it usually begins midseason, not after the final race. We're talking about the version of burnout that hides behind caffeine, adrenaline, and a packed travel schedule until reaction time drops, focus gets cloudy, and recovery stops working the way it used to.We break burnout down into a practical model built for motorsports professionals: deficiencies and toxicities. Deficiencies can be nutritional (magnesium, B vitamins, omega-3s, vitamin D3, antioxidants) and behavioral (sleep debt, poor recovery, low sunlight, weak nervous system regulation). Toxicities can be uniquely motorsports-heavy, including exhaust and shop chemical exposure, chronic inflammation, blood sugar instability, overtraining without recovery, and the slow cost of living in fight-or-flight. When those stressors pile up, you don't just feel tired, you accumulate physiological debt that steals performance.The fix isn't a one-size-fits-all routine. It's measurement and personalization. I share how functional lab testing can reveal what's actually driving fatigue and why tools like HRV tracking, continuous glucose monitoring, infrared sauna, and PEMF can help you stay ahead of the crash. If you want a season with better energy, sharper focus, and real resilience, hit play, then subscribe, share this with your team, and leave a quick review so more drivers and crew members can build a stronger finish. Sharpen your Champion's Edge with the exact 7-Day Dr. Cabral Detox protocol we use at Victory Lane Wellness to support liver detoxification, metabolic reset, nutrient replenishment, energy, recovery, and long-game health. Buy 3, Get 1 Free for a limited time: SAVE NOW! True champions don't just drink water — they fuel at the cellular level. The TheraH2Go+ Hydrogen Water Bottle delivers structured, hydrogen-rich hydration to boost energy, focus, and recovery from the inside out. Hydrate smarter, perform longer, and recover faster → SHOP NOW — use code VICTORY for your VLW Discount!. Support the showAs a token of gratitude, of course you're interested in these FREE and powerful resources, and because you enjoy the show, first be sure to leave your 5-STAR Review HERE!
The JournalFeed podcast for the week of May 25-29, 2026.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday's Spoon Feed:IV contrast doses used for CT scans appear to fall below the toxic threshold for nephrotoxicity, with no convincing evidence they cause acute kidney injury (AKI) in most patients.Tuesday's Spoon Feed:This Australian study found patients who were eligible for rapid rule out based on a single high-sensitivity cardiac troponin I (hs-cTnI) ≤2 ng/L pathway had shorter hospital length of stay (LOS) and no increase in index or 30-day cardiac events.
T-cell-engaging bispecific antibodies represent a major therapeutic and scientific advancement in the treatment of several types of cancer. However, they carry a risk of some unique acute toxicities, such as cytokine release syndrome and neurologic toxicity. This podcast reviews this emerging drug class and strategies for recognition and management of their unique adverse events. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.
When some sort of chemical or toxin is spilled in the environment it doesn't just stay put, it spreads, corrupting everything around it. The same principle is true in our organizations—toxic behaviors that are allowed to fester will spread until they consume your entire team. So put on your hazmat suit and join Greg and me as we address common toxic behaviors and offer strategies on how to root them out before they can take hold. Check out the video version of this conversation. Check out my blog, my other podcasts, my books, and so much more at http://linktr.ee/craigtowens ►► Would you please prayerfully consider supporting this ministry? My Patreon supporters get behind-the-scenes access to exclusive materials. ◀︎◀︎
00:00 Meet Alice Hart Davis01:58 How Treatments Began04:14 Buzzwords and Exosomes08:41 Treatments vs Lifestyle10:28 SPF That You'll Use11:36 Cosmoprof Finds13:34 Liposomal Skincare Truths15:44 Starting Your Journey18:27 Microneedling and IPL21:36 Needles to Surgery Spectrum23:12 Jaw Asymmetry Chat24:42 Polynucleotides Hype Check27:54 Oral Nucleotides Debate30:11 Gummies and Underdosing32:37 Why We Chase Youth34:10 Sculptra and Facelift Fears39:54 Bone Loss and Face Aging41:40 Fat Transfer and Nano Fat44:16 Mini Arm Lift Talk45:33 Squeamish but Curious46:29 Hairline Fix Surgery47:10 Amino Acids Prevention47:26 Collagen Origin Story51:41 Tripeptide Science Explained56:51 Proof and Credibility58:46 Real World Results01:00:44 Vegan Collagen Mythbusting01:04:43 Inflammation and Moisturising01:08:27 Spicules and Microneedling01:12:48 K Beauty and Longevity Trends01:17:16 Toxicity and Water Filters01:18:30 CEO Brain Testing01:26:36 Wrap Up and GoodbyeWatch the podcast on:▶︎ YouTubeFollow Elle-Sera for more:▶︎ Facebook▶︎ Instagram▶︎ LinkedInAbout Elle-Sera:Hormones aren't JUST anything. They make you who you are and control everything – your energy, mood, weight, confidence, hunger, motivation, outlook, libido the list goes on. The impact of hormone imbalance on our psychology and behaviour has been dismissed – until now. Let's stop diminishing the way we feel because of our hormones, by uttering those three little words: “I'm just hormonal”, and start embracing the power you can have over them. Elle Sera supports thousands of women to reclaim their hormones, including myself. Our golden pill is packed with five potent ingredients, carefully chosen to rebalance hormones in one essential daily dose.Produced by Liverpool Podcast Studios▶︎ Web▶︎ Instagram...
What if the contrast dye injected during your MRI scan never actually left your body and has been quietly causing damage ever since? In this episode of Integrative Cancer Solutions, Dr. K sits down with Debbie Heist Lambert, patient advocate, co-author of Gadolinium Deposition and Toxicity: Humanizing a Life-Changing Event, and community leader of a 15,000-member gadolinium toxicity support group. After receiving four gadolinium-based contrast injections during MRI scans for pancreatitis, Debbie was forced into early retirement at 56 due to debilitating memory loss, dementia-like symptoms, and a body-wide cascade of new diagnoses — all traced back to a toxic rare earth metal that her doctors refused to discuss. This conversation is a wake-up call for anyone who has ever had an MRI with contrast — especially cancer patients and those with MS who undergo repeated imaging. Dr. K and Debbie break down what gadolinium actually does inside the body, why it competes with calcium at the cellular level, how it may be connected to calcifications in breast tissue, the difference between chelation strategies, and why 91% of patients in Debbie's group say they were never given informed consent before injection. Key Takeaways: 0:00 Introduction 1:40 Debbie's personal journey with gadolinium poisoning 6:48 Why "you just pee it out" is false 8:54 Small fiber neuropathy, mast cell activation, and cytokine storms 12:35 Cancer and MS patients unknowingly worsening their condition 16:44 Gadolinium competes with calcium and hides in the body permanently 19:49 How to test for gadolinium retention 24:07 Why gadolinium deposition disease still isn't officially recognized 27:23 Chelation, HOPO trials, and niacin sauna detox options 34:19 The full symptom burden across eight years 38:49 91% of patients never received informed consent Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902 Resources: Gadolinium Deposition and Toxicity: Humanizing a Life-Changing Event - https://a.co/d/02oEJsME Dr. Brent Wagner Gadolinium Research - https://hscnews.unm.edu/news/unm-scientists-discover-how-nanoparticles-of-toxic-metal-used-in-mri-scans-infiltrate-human-tissue Dr. Richard Semelka - https://www.richardsemelka.com FDA Gadolinium Medication Guides - https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021489s006lbl.pdf HOPO Therapeutics - https://www.hopotx.com/ Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. ____________________________________RESOURCES FROM DR. KARLFELDT:
Comparison is stealing your focus. In this episode of The Level Up Podcast, Paul Alex breaks down why constantly watching other people's success can quietly destroy your confidence, momentum, and execution. Let's be real… If you spend your day studying someone else's highlight reel… Their income claims… Their follower count… Their lifestyle… You are wasting the exact energy you need to build your own future. In this episode, you'll learn: Why comparison destroys confidence and clarity How social media creates a false picture of success Why your own progress is the only metric that matters How to build an internal scorecard and stay locked in on your mission The truth is simple: You are not seeing the full story. You see the wins. You see the cars. You see the screenshots. But you do not see the debt. The stress. The turnover. The pressure. The problems behind the curtain. So stop measuring your real life against someone else's marketing. Your job is not to beat their timeline. Your job is to beat your old self. Track your own numbers. Improve your own execution. Protect your own peace. Build your own legacy. Because their success has nothing to do with your potential. Mute the noise. Put the blinders on. Stay in your lane. And keep leveling up. Your Network is your NETWORTH! Make sure to add me on all SOCIAL MEDIA PLATFORMS: Instagram: https://jo.my/paulalex2024 Facebook: https://jo.my/fbpaulalex2024 YouTube: https://www.youtube.com/channel/UCGhDAD1JyGGzSQUPD9lc9HQ LinkedIn: https://jo.my/inpaulalex2024 Looking for a secondary source of income or want to become an entrepreneur? Check out one of my companies below to see if we can help you: www.CashSwipe.com FREE Copy of my book “Blue to Digital Gold - The New American Dream”www.officialPaulAlex.com Learn more about your ad choices. Visit megaphone.fm/adchoices
You are unknowingly consuming an entire credit card's worth of plastic every single week. It's hiding in your tea bags, your store receipts, and even your $130 workout clothes. And the biological consequences are absolutely terrifying: studies show microplastics are now found in 100% of human testicles, they reduce mitochondrial energy by 35%, and they literally punch holes through your gut lining within 14 days. Uncover what's really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! → http://mybloodwork.com If you're ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com Thank you to our sponsors! Sunlighten Sauna: https://get.sunlighten.com/axepodcast Manukora Manuka Honey: https://manukora.com/axe Caraway Home: carawayhome.com/drjoshaxe (Use code DRJOSHAXE) for an exclusive discount Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1 Pre-order my NEW BOOK, Heal Your Cells → https://bit.ly/3QJBcQ5
Time toxicity and shared decision-making in cerebral palsyDavid B Frumberg, Paige T Church, Nathan RosenbergPMID: 41387091 DOI: 10.1111/dmcn.70123AbstractClinicians and families regularly enter into a process of shared decision-making. Seldom, if ever, however, is the critical question of time usage, or, more specifically, time-related burdens, accounted for when establishing goals and outcome measures. Time-related burdens are not included, for instance, as an outcome measure in cerebral palsy research-something which may have profound effects about which we are unaware. By contrast, in the field of oncology, time-related burdens, or, more technically, what has been termed time toxicity, has been increasingly studied. Building on that work, we seek to apply the concept of time toxicity to people with disabilities who interface with healthcare at great frequency.https://pubmed.ncbi.nlm.nih.gov/41387091/
In this episode of the Oncology Brothers podcast, we dived deep into the world of BRAF V600E-mutated non-small cell lung cancer treatment options. Joined by Dr. Melissa Johnson, a thoracic medical oncologist and director of lung cancer research at the Sarah Cannon Research Institute, the discussion focused on two critical BRAF and MEK inhibitor combinations: Dabrafenib plus Trametinib and Encorafenib plus Binimetinib. Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Apple Podcast: https://podcasts.apple.com/us/podcast/oncology-brothers-practice-changing-cancer-discussions/id1653340966 Follow us on social media: X/Twitter: https://twitter.com/oncbrothers Instagram: https://www.instagram.com/oncbrothers Website: https://oncbrothers.com/ Key topics included: Overview of the efficacy and survival data for both combinations Side effect profiles and management strategies Clinical pearls for oncologists in practice The importance of NGS testing in smokers and the role of targeted therapy versus chemoimmunotherapy Join us as we explore the latest insights and recommendations for managing these therapies, ensuring better patient outcomes and quality of life. Don't forget to check out our previous episodes for more on treatment algorithms and conference highlights! #BRAFmutation, #NSCLC, #BRAF-MEK-inhibitor, #TargetedTherapy, #OncologyBrothers
I love tennis. I love talking about tennis. I love having discussions with other fans about players who are great, players who could be better, things that I love about tennis, and things that annoy me.I love the GOAT debate. How fun is it to compare stats, types of shots and game style, and have the evening extend into the late hours as we let our outrageous opinions on the table, call our friends idiots, then laugh it out and go home in peace?But on social media...Everything has to be different.Fans love to throw insults at the first opportunity. Taking things we say out of context. Insulting our intelligence. Going as far as mocking our physical appearance, incessantly leaving mean comments in our replies.Harassing players has become normal. Fans thinking they know better, that they can give priceless advice from the comfort of their homes thousands of miles away, watching tennis from a set tv angle that simply can't give you all the information you need to properly assess the game, even if you were a real professional tennis expert - which in the vast majority of cases we are not.This podcast is not for players. They can get their information from highly trained personnel with years of experience and their inner circles of people they trust. My analysis and comments do not bring them any benefit.This podcast is for fans. But I would truly love it if we could just be in love with this insane sport, have loads of fun, trash talk at each other respectfully, and keep a cool head over our shoulders knowing that there are millions of people around the world who are just are crazy about tennis as we are.We can't all be friends and love each other. We have moments of anger and frustration. Sports is like that, I know it well. But we don't have to hate each other, or get aggressive online simply because someone has a different opinion than ourselves.It's just a game, y'all. A game we love and are worse of without, but still a game. Let's love it well and respect each other and the players who give us all those great moments.Favourite this podcast if you like our work :)SUBSCRIBE to the YouTube channel!Follow TENNIS AND BAGELS!Twitter/X: https://x.com/TennisAndBAGELSAndre:Twitter/X - https://x.com/RolembergAndreBlueSky Social: https://bsky.app/profile/andrerolemberg.bsky.socialVansh: https://x.com/vanshv2kOwen (BlueSky Social): https://bsky.app/profile/owensports.bsky.socialSupport this show http://supporter.acast.com/tennis-and-bagels. Hosted on Acast. See acast.com/privacy for more information.
I love tennis. I love talking about tennis. I love having discussions with other fans about players who are great, players who could be better, things that I love about tennis, and things that annoy me.I love the GOAT debate. How fun is it to compare stats, types of shots and game style, and have the evening extend into the late hours as we let our outrageous opinions on the table, call our friends idiots, then laugh it out and go home in peace?But on social media...Everything has to be different.Fans love to throw insults at the first opportunity. Taking things we say out of context. Insulting our intelligence. Going as far as mocking our physical appearance, incessantly leaving mean comments in our replies.Harassing players has become normal. Fans thinking they know better, that they can give priceless advice from the comfort of their homes thousands of miles away, watching tennis from a set tv angle that simply can't give you all the information you need to properly assess the game, even if you were a real professional tennis expert - which in the vast majority of cases we are not.This podcast is not for players. They can get their information from highly trained personnel with years of experience and their inner circles of people they trust. My analysis and comments do not bring them any benefit.This podcast is for fans. But I would truly love it if we could just be in love with this insane sport, have loads of fun, trash talk at each other respectfully, and keep a cool head over our shoulders knowing that there are millions of people around the world who are just are crazy about tennis as we are.We can't all be friends and love each other. We have moments of anger and frustration. Sports is like that, I know it well. But we don't have to hate each other, or get aggressive online simply because someone has a different opinion than ourselves.It's just a game, y'all. A game we love and are worse of without, but still a game. Let's love it well and respect each other and the players who give us all those great moments.Favourite this podcast if you like our work :)SUBSCRIBE to the YouTube channel!Follow TENNIS AND BAGELS!Twitter/X: https://x.com/TennisAndBAGELSAndre:Twitter/X - https://x.com/RolembergAndreBlueSky Social: https://bsky.app/profile/andrerolemberg.bsky.socialVansh: https://x.com/vanshv2kOwen (BlueSky Social): https://bsky.app/profile/owensports.bsky.socialSupport this show http://supporter.acast.com/tennis-and-bagels. Hosted on Acast. See acast.com/privacy for more information.
Welcome to the Oncology Brothers podcast! In this episode, we dived deep into the world of bispecific antibodies approved for multiple myeloma. Joined by myeloma specialists Dr. Hamza Hashmi from Memorial Sloan Kettering and Dr. Cesar Rodriguez from Mount Sinai, they discussed the latest updates, clinical pearls, and practical insights for community oncologists. Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Apple Podcast: https://podcasts.apple.com/us/podcast/oncology-brothers-practice-changing-cancer-discussions/id1653340966 Follow us on social media: X/Twitter: https://twitter.com/oncbrothers Instagram: https://www.instagram.com/oncbrothers Website: https://oncbrothers.com/ Key topics included: Overview of bispecific antibodies, focusing on GPRC5D and BCMA-targeted therapies. Detailed discussion on talquetamab, teclistamab, elranatamab, and linvoseltamab, including dosing, side effects, and management strategies. Insights on managing cytokine release syndrome (CRS), neurotoxicity, and other side effects like dysgeusia, skin toxicity, and infections. Prophylactic measures, including the use of IVIG and tocilizumab, to enhance patient care and quality of life. Whether you're a healthcare professional or simply interested in the latest advancements in cancer treatment, this episode is packed with valuable information. Don't forget to like, subscribe, and check out our other episodes for more insights into oncology! #MultipleMyeloma, #BispecificAntibody, #ICANS, #CRSmanagement, #OncologyBrothers
In this episode, hear Doris K. Hansen, MD, discuss the management of relapsed/refractory multiple myeloma with bispecific antibodies including: Practical differences among approved bispecific antibodies Toxicity profiles of approved bispecific antibodies When to refer patients for evaluation for immunotherapies Considerations for sequencing bispecific antibodies in the relapsed/refractory setting New findings with combination regimens with bispecific antibodies Program faculty: Doris K. Hansen, MD Assistant Member, Blood and Marrow Transplant and Cellular Immunotherapy H. Lee Moffitt Cancer Center & Research Institute Assistant Professor University of South Florida Morsani College of Medicine Tampa, Florida Link to program page:https://bit.ly/4nufxr2 Get access to all of our new podcasts by subscribing to the Decera Clinical Education Oncology Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
AI Unraveled: Latest AI News & Trends, Master GPT, Gemini, Generative AI, LLMs, Prompting, GPT Store
In this episode of the Oncology Brothers podcast, we dived into the world of anti-EGFR therapies in non-small cell lung cancer (NSCLC). Joined by Dr. Joshua Sabari from NYU Langone Health and Dr. Azam Farooqui from Ironwood Cancer and Research Center, we discussed the latest advancements in treatment options, including the use of osimertinib, afatinib, and the combination therapy of amivantamab and lazertinib. Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Apple Podcast: https://podcasts.apple.com/us/podcast/oncology-brothers-practice-changing-cancer-discussions/id1653340966 Follow us on social media: X/Twitter: https://twitter.com/oncbrothers Instagram: https://www.instagram.com/oncbrothers Website: https://oncbrothers.com/ Key topics include: The role of afatinib in treating uncommon EGFR mutations and its associated toxicities The well-tolerated profile of osimertinib and its common side effects, including rash, diarrhea, and the rare risk of pneumonitis Insights into the combination therapy of amivantamab and lazertinib, including management of skin toxicity and the importance of prophylactic anticoagulation to mitigate VTE risks The episode emphasized the importance of maintaining quality of life for patients while ensuring they can stay on effective therapies for longer periods. Tune in for valuable clinical pearls and strategies to optimize patient care in the community setting. Don't forget to like, subscribe, and check out our other episodes for more insights on treatment algorithms and conference highlights! #LungCancer, #NSCLC, #EGFR, #TargetedTherapy, #OncologyBrothers
In one's UX operation, encountering various aspects of toxicity is a reality. How can we recognize toxicity? How can we manage it? Is it manageable? This week, Dr. Darren identifies several aspects of toxic behavior in the form of what are known as the isms and shares tips on how to be the victor when experiencing the same.#ux#podcasts#cxofmradio#cxofm#realuxtalk#worldofux#worldouxBookmark the new World of UX website at https://www.worldoux.com. Visit the UX Uncensored blog at https://uxuncensored.medium.com. Get your specialized UX merchandise at https://www.kaizentees.com.
Can upholstery innovate without toxicity? Or are we stuck between outdated regulations, industry habits and the fear of change?This week Vicky and Ray sit down with Delyth Fetherston-Dilke, one of the leading voices challenging the UK furniture industry to think differently about flame retardants, materials, sustainability and the future of upholstery.But this conversation goes far beyond “toxic foam”.We get into the real questions:Are current fire regulations still fit for purpose? Why is innovation in furniture materials so difficult? Who really influences what upholsterers are able to buy and use? And can the industry evolve without losing safety, craftsmanship or trust?Delyth shares her experiences working across campaigning, regulation and industry conversations, alongside her belief that innovation, transparency and collaboration are essential if upholstery is going to move forward.This is an honest conversation about materials, manufacturing, health, responsibility and the complicated reality of change within traditional industries.FR ConsultationCheck out that amazing article in TheTimeshttps://www.thetimes.com/life-style/property-home/article/sofas-toxic-chemicals-cancer-9tz66br9c“Dark Waters” Movie: https://tv.apple.com/gb/movie/dark-waters/umc.cmc.3topp2g12va4hj1i9v50f13g7Fidra CharityThe Environmental charity supporting sustainability & preventing pollution: https://fidra.org.uk Our profound thanks go out to all our SponsorsMartins Upholstery SuppliesBeA Group Follow Sit on This! for monthly chats from the workbench, stories from inside the upholstery world, with makers, fixers, and fabric lovers.
DL, Evil, and Rachel dig into System of a Down's Toxicity (2001) — one of the biggest metal albums ever made, debuting at #1 the week before 9/11 and getting Chop Suey immediately pulled from radio.The central argument: Toxicity is not a nu-metal record. It's one of the most coherent political albums ever made — a sustained meditation on apathy, incarceration, the Armenian-American experience, and what happens when society stops giving a shit about each other. Prison Song, Needles, ATWA, and "somewhere between the sacred silence and sleep" hit completely different when you actually listen to what Serj Tankian is saying.Along the way: why "Chop Suey" was originally titled "Suicide" (and how the rename was pure SOAD genius), the story of Rick Rubin seeing them at the Viper Room in 1997 and immediately knowing, Daron Malakian's insistence the album fit on one side of a tape at exactly 40 minutes, the time signatures and hemiola that make Toxicity sound heavier than it should, and the direct sonic DNA connecting Faith No More's Epic piano outro to Chop Suey's ending.The influence arc: System of a Down directly cited Faith No More as a key influence — this episode is part of a two-week influence-to-influence series starting with The Real Thing.Scores: Rachel 10/10, Evil 10/10, DL 9.8/10.Part of Verse Chorus Verse's album-by-album deep dive series.System of a Down,Toxicity,Chop Suey,Serj Tankian,Daron Malakian,Rick Rubin,metal album review,Armenian rock,2001 albums,political metal,Faith No More influence,music podcast
YouTube DescriptionThey said men are the “second sex,” AI is just womb envy, military vaccines are basically government-sponsored trauma bonding, and somehow this episode still found time for Hershey squirts, bad backs, David Goggins, fake combat valor, sex robots, Sigourney Weaver, and why civilians may never understand the peanut butter shot.This one goes from biology arguments to boot camp horror stories, from toxic internet gender takes to military pragmatism, from “can a penis be a biological weapon?” to “why Chino is building a homie.”It is offensive. It is unhinged. It is probably medically inadvisable.And somehow, it still makes more sense than half the internet.Welcome to another sacrilegious Sunday with Chino and Homeboy.Buy the books. Watch the pod. Blame the algorithm.#ChinoAndHomeboy #Podcast #ComedyPodcast #VeteranComedy #MilitaryHumor #RageBait #GenderWars #AI #DavidGoggins #UnfilteredComedy #DarkComedy #SacrilegiousSundayTimestamps00:00 Intro, Sacrilegious Sunday begins03:59 Modern Whore, memoirs, indie authors, and literary hustling06:34 Lumbago, aging, back pain, and cocaine suggestions13:27 Hey Jones' sickness story begins26:36 Hyper-advanced AI, sentience laws, and sex robots29:02 Strep throat, vaccines, Wolverine logic, and superhero science30:34 Boot camp peanut butter shots and vaccine gauntlets33:47 Military vaccine records and civilians not understanding anything36:13 Pete Hegseth, combat claims, and stolen valor talk38:30 Voting against interests, whiteness, and political identity41:47 Book ad, bathroom reading, and shameless plugging42:49 “Men are the second sex” rage bait begins44:00 Ex Machina, womb envy, AI, and fake life45:01 Male sex drive, ovulation talk, and “dial it to 11”49:09 Women create life? Men fertilize? The biology fight50:15 Spawn points, NPCs, and simulation logic55:16 AI sex robots and why men build fake women58:16 Who chooses mates, leadership, and bad internet arguments01:00:13 Male and female development, anatomy chaos, and dick capes01:02:03 “Men weren't meant to lead?” Then pick where to eat01:03:09 Women supervisors, pragmatism, and workplace leadership01:06:22 Male-female dynamics and the “fuck protocol”01:08:15 Combat roles, physical standards, and pulling your weight01:20:35 Special operations, standards, and mission failure talk01:30:00 Workplace toughness, gender expectations, and labor culture01:45:17 Ass metaphors, methadone clinics, and conversation collapse01:55:20 Endurance races, hard people, and athletic freaks02:00:04 David Goggins worship reaches maximum hardness02:05:02 Money bets, attraction, lawyers, and relationship math02:10:10 Toxicity, science, sexual frequency, and brutal attraction studies02:20:08 Investigations, public claims, and internet traction02:24:41 Comedy show story, yellow shirts, and getting picked on02:40:14 Military gear, aircraft talk, and tactical rabbit holes02:45:09 SEAL teams, SDV billets, and special warfare details02:50:00 Chino is building a homie, and it is apparently everyone's fault02:52:05 Sigourney Weaver, Alien, Ridley Scott, and national treasure arguments02:54:01 Wrap-up and outro
In this episode of the HOMe Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz explore a foundational principle of Health Optimization Medicine: What's toxic to the cell is toxic to every organ. Through real clinical cases — including mercury toxicity, arsenic exposure, and environmental toxin accumulation — the team reveals how modern medicine often misses the root cause of disease by focusing on isolated organ systems instead of cellular function. From chronic low-level toxin exposure to acute breakdown events, this episode highlights how toxins disrupt mitochondrial energy production, leading to widespread dysfunction across the body. Most importantly, the conversation emphasizes the role of metabolomics in identifying these hidden stressors early — before they manifest as disease. Join us as we delve into: • Why toxins affect every organ through the cell • A real case of mercury toxicity missed by multiple specialists • How chronic exposure becomes acute illness • Why traditional medicine misses root causes • The role of mitochondria in energy production and health • How metabolomics detects early toxicity and dysfunction This episode is for you if: • You want to understand the root cause of chronic illness • You're exposed to environmental toxins (food, water, air) • You're interested in preventative and optimization-based medicine • You want to take a proactive approach to long-term health You can also find this episode on…Youtube: https://youtu.be/CMhFC5IUKl0 Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
Self-care podcast exploring Key Imbalances and Toxicity in the Body, Reviewing my HTMA Test Results with you & Key Foundations for Healing with Dr. Stephen Cabral TOPICS:: ** Key Imbalances and Toxicity in the Body (08:11). ** Reviewing my HTMA Test Results with you (19:31). ** Key Foundations for Healing (39:48). NOTES:: Show notes: amberapproved.ca/podcast/662 Leave me a review at amberapproved.ca/review Email me at info@amberapproved.ca Take the NEW Free Hormone Imbalance Quiz here: https://amberapproved.ca/hormone-imbalance-quiz Subscribe to newsletter: https://amber-romaniuk.mykajabi.com/newsletter-sign-up SHOW LINKS: Click below to schedule a 30 minute Complimentary Body Freedom Consultation https://amberapproved.ca/body-freedom-consultation/ Take my free Emotional Eating Quiz here: http://amberapproved.ca/emotional-eating-quiz Listen to Episode 291 about what it's like to work with me here: http://amberapproved.ca/podcast/291/ Follow me on Instagram www.instagram.com/amberromaniuk Youtube Channel: https://www.youtube.com/@amberromaniuk/ ABOUT MY GUEST: Dr. Stephen Cabral is a Board-Certified Doctor of Naturopathy and founder of EquiLife, the global integrative health organization providing at-home lab testing, personalized wellness protocols, and concierge health coaching to over 300,000 clients over the past 25 years. He also founded the Integrative Health Practitioner Institute (IHPI), which has certified over 5,000 practitioners globally, and hosts The Cabral Concept podcast with 3,500+ episodes and 100 million+ downloads. After overcoming a life-threatening illness at 17, Dr. Cabral went on to get his doctoral degree and completed over 2,200 internship hours all over the world including India, Sri Lanka, China, Europe, and the U.S. His latest book, Personomics, is the culmination of his life's mission to provide a personalized approach in helping people transform their health in both mind and body. https://stephencabral.com/ Get your free HTMA Test: Mineral deficiencies are stealing your energy, and toxic heavy metals are inflaming your body. Some of the most overlooked aspects of health are measured with a simple Hair Tissue Mineral Analysis Test. This test will uncover all of your mineral levels, electrolytes, and toxic heavy metals. This will give you insight into why you're struggling with chronic low energy, anxiety, brain fog, and more. This is the first test that Dr. Cabral ever ran, and it opened the door for him to finally get well. Now, he's paying it forward by offering 100 of these tests for free each month to first-time lab clients ($199 value). All you cover is the shipping & handling, and everything else is included completely free. Simply go to StephenCabral.com/Sugar to claim your free test. This test is completely free... You just pay the shipping and handling cost. ($199 value) The shipping and handling cost is $17.95 because it also includes return postage and processing, so that it's as easy as possible for you to send back your sample and get your results MY PARTNERS: Designs For Health Blood Sugar Bundle! One of the hardest parts of overcoming my emotional eating was the INSANE SUGAR and carb cravings. It was the intense sugar and carb cravings. That's why I created my Blood Sugar Bundle with Designs for Health to support your body while you work on emotional eating and breaking binge patterns. It includes chromium for blood sugar balance, L-glutamine to help curb cravings fast, a high-quality probiotic for gut health, and a clean Pure Paleo protein powder to keep you full and stable. I only recommend Designs for Health to my clients because they are third-party tested, family-owned, and use the highest quality ingredients. Quality matters when it comes to truly supporting your body and getting results. Get 30% off The Blood Sugar Bundle in USA and Canada automatically applied at checkout below! Canada Blood Sugar Bundle here for 30% off! USA Blood Sugar Bundle here for 30% off! You can also get 30% off any Designs for Health supplements anytime, it's my gift to you. Canada: www.designsforhealth.ca (code AMBER30) USA: www.designsforhealth.com (code AMBER88)
DL, Evil, and Rachel dig into Faith No More's The Real Thing (1989) — the album that accidentally invented nu-metal, made "Epic" a cultural phenomenon, and was written entirely by a 19-year-old Mike Patton who had never met the band before.The central debate: did Epic's massive MTV success actually hurt Faith No More's legacy by making casual listeners think they were a one-hit wonder? And is The Real Thing even their best album — or does Angel Dust win that argument by a mile?Along the way: the story of how Courtney Love almost got the singer job, the Chuck Mosley firing, why Billy Gould's bass on this album is the direct ancestor of Fieldy in Korn, how "Surprise You're Dead" at the 38-second mark contains one of the best gear shifts in rock, and a deep dive into why Epic's piano outro resolves a tritone (the "devil's interval") that the main riff deliberately left open.The influence argument: System of a Down have cited Faith No More as a direct influence — and the parallels between Serj Tankian and Mike Patton, and between Daron Malakian and Jim Martin, are hard to ignore. This episode sets up next week's Toxicity deep dive.Scores: Rachel 7/10, Evil 8.5–9/10, DL 8.3/10.Part of Verse Chorus Verse's influence-to-influence album arc.Faith No More,The Real Thing,Mike Patton,Epic,alt-metal,nu-metal,1989 albums,Angel Dust,System of a Down,album review,music podcast,funk metal
In this episode, Dr. Hugh talks with Talia Smith about her experience after taking Cipro, a fluoroquinolone antibiotic. Talia shares how her health changed, how hard it was to be heard in the medical system, and what she learned after years of dealing with symptoms. Scedule a Zoom call and find out what's been missing!This episode is for people who are searching for answers about fluoroquinolone toxicity, Cipro side effects, mast cell activation, histamine reactions, food sensitivity, and medical gaslighting.In this episode, you will hear about:How Talia's symptoms started after taking CiproWhy fluoroquinolone toxicity can be so confusingHow the medical system can miss antibiotic injuryWhy some people feel dismissed or labeled as “crazy”How food reactions, histamine issues, and mast cell problems may show upWhy listening to your body mattersHow finding the right support can make a differenceWhy hope still matters during recoveryTalia also talks about the importance of learning, asking better questions, and finding people who understand what may happen after fluoroquinolone antibiotics.Key topics:Cipro toxicityFluoroquinolone toxicityFloxed recoveryAntibiotic injuryMast cell activationHistamine intoleranceMedical gaslightingFunctional medicineChronic health symptomsThis conversation is meant to help people feel less alone and more informed as they look for answers.
Skin reactions during pediatric cancer treatment can be painful, stigmatizing, and sometimes threaten a child's ability to stay on therapy. In this episode of PeDRA Pearls, Dr. Christina Boull and Dr. Rebecca Levy discuss PeDRA's Skin Tumors and Reactions to Cancer Therapies (STARC) Focused Study Group and its work to prevent, recognize, and manage these toxicities. They highlight multicenter efforts spanning photosensitivity prevention, survivorship outcomes, and targeted therapy side effects—including MEK inhibitor–associated mucocutaneous toxicities—plus the need for stronger derm–onc collaboration, better trial reporting, and evidence-based consensus guidelines.Click here for more information.
A tweet from some dude claims that the toxicity directed at Matt Rhule is WORSE with him than it has been with other Nebraska coaches.
We continue the conversation from earlier about the toxicity displayed towards Matt Rhule compared to other Nebraska coaches.
Are your "healthy" protein shakes loading your body with toxins? It's easy to assume supplements are clean, yet the data tells a very different story. When nearly half of protein powders exceed safety limits for heavy metals, it raises a serious question of whether they are helping or harming our bodies. Today I'm chatting with Oliver Amdrup-Chamby, CEO of Puori, to unpack what's really inside protein powders, collagen, and omega-3s. We talk about shocking industry findings, including testing that revealed widespread contamination, especially in plant-based proteins. Oliver shares how his company tests for over 200 contaminants and why transparency is the future. We also break down whey versus plant proteins, chocolate contamination, and how sourcing impacts your long-term health. If you're taking supplements daily, this conversation is essential. You'll learn what to look for on labels and how to make smarter choices. "Most pollution of our bodies doesn't come from a one-off exposure to a certain food. It comes from the accumulation of the things you're doing again and again." ~ Oliver Amdrup-Chamby In This Episode: - Oliver's backstory and why he co-founded Puori - Omega-3 quality and longevity - Heavy metals and other toxins in protein powders - SB 1033 regulation push and its significance - Heavy metals in chocolate protein powder - Types of protein powders: whey vs plant proteins - Toxicity in various powders, and concerns about soy protein isolate - Sustainable packaging versus purity - Quality ingredients and supplement testing for Puori products - Why Puori discontinued some products Products & Resources Mentioned: Puori - PW1 Grass-fed Whey Proteins: Use code WENDY to get 32% off your first order and get a free shaker worth $25 when you start a subscription at http://puori.com/wendy Tru Energy Bio Adaptive Hydration Oil: Try the oil and save up to $197 at http://trytruenergy.com/wendy5 Organifi Happy Drops: Save 20% with code MYERSDETOX at https://organifi.com/myersdetox Organifi Collagen: Save 20% with code MYERSDETOX at https://organifi.com/myersdetox Fresh-Pressed Olive Oil: Try a full-size $39 bottle for just $1 to cover shipping at https://getfreshwendy.com Heavy Metals Quiz: Find out your toxicity score and receive a free video series on detoxification at https://heavymetalsquiz.com About Oliver Amdrup-Chamby: Oliver Amdrup-Chamby is the co-founder and CEO of Puori, a Danish health supplement company focused on transparency and purity. With over 15 years in the industry, he pioneered third-party batch testing for contaminants in supplements. He has a background in business, fitness, and CrossFit leadership, and is passionate about longevity, performance, and data-driven health optimization. Learn more about their line of clean supplements at: http://puori.com Disclaimer The Myers Detox Podcast was created and hosted by Dr. Wendy Myers. This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast, including Wendy Myers and the producers, disclaims responsibility for any possible adverse effects from using the information contained herein. The opinions of guests are their own, and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.
Featuring perspectives from Dr Aditya Bardia and Dr Erica Mayer, including the following topics: Introduction: How Selective Estrogen Receptor Degraders (SERDs) Work (0:00) Second-Line Treatment for Metastatic Breast Cancer (16:01) First-Line Therapy for Metastatic Disease (33:19) Adjuvant Therapy (35:26) Toxicity, Quality of Life (47:59) New Directions (55:22) CME information and select publications
Join Bella as she dives into the latest in reality TV, including summer house scandals, Love on the Spectrum insights, and the drama of Bravo's hottest moments. Get her unfiltered take on celebrity leaks, show updates, and her personal journey through the chaos.Chapters00:00 Introduction and Personal Updates05:40 Content Plans and Scheduling Challenges10:36 Engagement with Reality TV and New Ideas14:32 Reality TV Highlights and Discussions20:02 Breakup Season in Reality TV23:12 The Impact of Breakups on Love24:47 Reality TV Relationships and Cheating Scandals28:03 Toxicity in Relationships and Personal Reflections30:05 Updates on Reality TV Shows and Spin-offs32:32 The Intersection of Religion and Reality TV35:12 Reality TV Drama and Personal Connections37:00 Controversies and Character Dynamics in Reality Shows45:50 The Best and Worst of Reality TV EpisodesSupport the showFollow me @BellaTalksTV
“I'm getting in touch because I've written the attached open letter as a serving Garda,” this email was one of many we received since Sinead O'Sullivan came on the podcast. “I've never done anything like this before,” it continued, “but I felt I had to say something given how things are going. I wrote it out of a genuine sense of frustration with the direction the country seems to be heading. More than that, I'm writing as a father of a young family, and I'm increasingly worried about what kind of Ireland my kids are going to grow up in.”On Free State today we ask why people hurting has been turned into an urban versus rural debate when everyone is affected. Does this tell us something about the inability of the ruling class to see beyond the short term? Why is there always a defensive attack or a short term fudge rather than leadership?And when it comes to lack of leadership? Could things actually get worse for Mayo? Hosted on Acast. See acast.com/privacy for more information.
Dr. Deb Muth 0:03What are the answers to your child’s chronic allergies, ADHD, or autism?weren’t just in another prescription, but in restoring balance to their body chemistry. Today’s guest has spent nearly two decades uncovering those answers through integrative and biomedical medicine. That’s a mouthful, isn’t it?Helping children heal when nothing else seemed to work.This is the conversation about science, compassion, and changing the future of pediatric care.Welcome back to Let’s Talk Wellness Now. The show where we uncover the root causes of chronic illness, explore regenerative breakthroughs, and empower you with the practical tools to heal. I’m your host, Dr. Deb, your medical detective, and today’s episode is one every patient should hear.My guest is Dr. Anu Usman Singh, Medical Director of True Health Medical Center in Naperville, Illinois, and the owner of Pure Compounding Pharmacy.And for over 17 years, she has been pioneering evidence-based integrative interventions for children with ADD, autism, allergies, and complex gastrointestinal and metabolic disorders. She’s not only a practicing physician, she’s a researcher who’s investigated copper-zinc imbalances.metallonine dysfunction, biofilm-related infections, vitamin D in pregnancy, and hyperbaric oxygen therapy.Dr. Usman serves on the executive board of TACA, and is a faculty member at MAPS, training other practitioners in pediatric integrative care. So get ready for a conversation that will open your mind and heart to the possibilities of when medicine truly becomes holistic.If you guys can insert the ad in here, that’d be great.Well, welcome back. I’m so excited to have Dr. Usman with me today. I have known her for, oh my gosh, 15, 17 years, something like that. We’re aging ourselves. Anju 02:32Oh, yeah, when we were in our 20s, right? Dr. Deb Muth 02:35Yes, exactly. So, welcome back, and I am so excited for you to be here, because you have literally helped thousands of families over the years.But I’d love for you to share a little bit about your journey, kind of who you are, what drew you into exploring integrative and biomedical approaches for helping children and families. Anju 02:58I think my journey is similar to a lot of you out there, the audience. I mean, we’re looking to help our families, and our kids, and ourselves, and I was doing my residency at Cook County Hospital, downtown Chicago, in the 80s.And I thought, oh my goodness, if I could take care of the sickest patients, then I can take care of anybody. So I came from Indiana, and I went to Cook County, and my children, my eldest daughter, started having, severe allergies and asthma, really, really at a young age.And I went to, like, my residence, and I went to my attendings, and I said, this baby is wheezing. And they told me, babies don’t have asthma.And I said, she has all the symptoms of asthma. She has asthma. And I remember with, in her crib, I would just nebulize her, you know, and I was like, what is going on?And I figured out that she had a lot of food allergies, and I was nursing her, eating the foods that she was allergic to, and back then, in the 80s, you know, we didn’t have the internet, we didn’t have Whole Foods, and I just…being a doctor, and I didn’t even know what to do, and I felt so hopeless. And I thought, gosh, you know, I’m a doctor, I have these, like, skills, I have… people I can talk to, and I still feel so… it’s so difficult. And then this… my particular daughter, the oldest one, her name is Priya, and she developed severe, asthma, and I couldn’t figure it out. She was in junior high. Every time she would walk into the lunchroom, she would have a severe asthma attack.And I’ll be like, what’s going on? What’s going on? I kept her home over the weekend, she was better. I sent her back to school, she was bad again.And we figured it out that it was other people eating peanuts. Dr. Deb Muth 04:54Severe peanut allergy. Anju 04:56And I went to the school, and I said, she…can you, like, put her somewhere else? Can… they said, oh, no, that’s not fair to other kids and their food. And this was in the 90s. Dr. Deb Muth 05:10Yeah. Anju 05:10And so, I just…You know, my heart goes out to families who are struggling to find answers for their kids, and my daughter Priya, the one I told you about, she ended up passing away from a peanut allergy.And so, I’ve just… Dr. Deb Muth 05:26Yeah. Anju 05:27My heart goes out to parents and my own kids and their illnesses.And so I just started working with families, with kids, andIt just kind of grew from there. Dr. Deb Muth 05:40Yeah. Yeah. Yeah, and I think being a mom who went through that yourself, and…was seen but not heard, and turned away from the traditional medical community, you’re forced to start finding answers on your own. And we always feel like we’re on an island by ourselves in the medical world when we’re doing that. Anju 06:01Yeah, I, it was really hard when I found out, you know, about…Integrative medicine, and just different…ideas and approaches to diet and supplements, I thought, how come I wasn’t trained in any of this?And… Dr. Deb Muth 06:21So angry when I learned some of the things that I learned in the beginning. I was like, same thing, like, how did they not teach us this? And then I think, you know, it’s my fault, was I asleep, was I not paying attention, whatever. And then you just realize, like, there’s this whole part of the human body.That they just didn’t teach us. Anju 06:42Yeah, so then I… I, probably like you, we had to learn it on our own. There weren’t, like, classes or any way to learn this stuffAnd I just reached out. There’s a clinic that,I don’t know if you’ve heard of the Pfeiffer Treatment Center? Dr. Deb Muth 07:00No. Anju 07:01Do you know Carl Pfeiffer from the attendees.He has a clinic called the Pfeiffer Treatment Center in New Jersey. It was called the Princeton Brain Bio Center. Dr. Deb Muth 07:12And in the 70s, they did orthomolecular medicine for patients with ADD. Anju 07:18And schizophrenia. Dr. Deb Muth 07:20Mmm… Anju 07:21and depression.And they used to categorize them in 3 categories, and at the time, they called them histopenics, histidelics, and pyrolurics. Dr. Deb Muth 07:31Okay. Anju 07:32Histapenix were low histamine patients.Delix were high histamine patients, and pyrolurics were their own kind of category. We added another category of copper-zinc imbalances, and then we would categorize that population into high histamine, low histamine, pyrolurics, and copper-zinc.Now we talk about under-methylation, over-methylation. Sure. So, under-methylation is the, you know, the high histamine people, they can’t clear the histamine. And the over-methylators are, you know, what we call about low histamine now.And, and then pyrolurics and copper zinc. So…I lost my train of thought, but in the 80s, when I was going through this, in the 90s, I reached out to the Pfeiffer Treatment Center.He’s like, can I calm and just hang out and, like, see what you guys do? Because I need some answers.And I started working there and, started doing research on copper-zinc imbalances, and I did it in children with autism.And that’s how people started coming to me, and I kinda got, like. not famous, but I, you know, the word spread about, okay, we could talk about it, and Dr.Walsh was the, you know, PhD there that did a lot of the research, so we worked together for 8 years. Dr. Deb Muth 09:05Isn’t it crazy to think that we knew about histamine issues way back in the 70s? You know, I got the pleasure of being trained by, environmental medicine doctors. Dr. Wayne Konetsky and Glenn Toth taught me about environmental medicine, and what we called histamine issues that we call it today, mast cell, right? But when I was learning in the early 2000s, it was labeled as chemical sensitivity. And so it was just people that would react to everything, and we really didn’t know why, and they didn’t necessarily have this very specific allergic reaction, but we knew they were reacting, and we would try to treat them, to lower the histamine way back then. And it’s taken all these years, 25 years, to get to a point where we understand mast cell activation now, and histamine issues.And it’s really sad to me that it’s taking this long for us to identify things.And we’ve all got our journey, and I loved back in those days, too, because as I learned, I would call people up and say, hey, I just got a patient from you, and they told me this great story, and I have other people, can I come see what you were doing? And back then, everybody was very open. They were like, yes, please, come, learn. Now everybody’s like, oh, we can’t teach you, we can’t give you our secrets, but…Or pay me $20,000 to come learn with me. But back then, I mean, everybody was just… we were all in the same boat. We were all just trying to learn from each other. Anju 10:36Oh, yeah, oh yeah, and any bit of knowledge you got, you’re like… Dr. Deb Muth 10:41Yes. Anju 10:41God, you know, I learned this piece, and… Dr. Deb Muth 10:43Hmm? Anju 10:44We just kind of built from that. I keep thinking about back then, you know,the under-methylators, over-methylators, copper, zinc, and then I learned about metals.And then, as a physician, I was like, oh, okay, well, there’s mercury in vaccines, there’s aluminum in vaccines, and now I’m seeing these high levels. Dr. Deb Muth 11:04In my patients, now what happens? Anju 11:07And then we started, kind of, trying to get the word out about those things. Dr. Deb Muth 11:13Yeah. Anju 11:13And in 2000, a lot of the people that I knew put out a paper about, you know, mercury. Dr. Deb Muth 11:22And then… Anju 11:22And we all got on the Mercury bandwagon. Dr. Deb Muth 11:25Yes. Anju 11:26And did that for a while, and then we started learning about other things, like mitochondrial issues in chronically ill people, and these chronic infections, like Lyme disease, and so… and then now, you know, understanding mast cell activation, cell danger response. Dr. Deb Muth 11:44On endocrine, and adrenals, and hormones, and… Anju 11:48Yeah. Dr. Deb Muth 11:49biofilms. Anju 11:50Biofilms, I started talking about that in 2007. Dr. Deb Muth 11:54And so then… Anju 11:56It just… it just kind of keeps adding, and keeps adding, and keeps adding, and it’s like…Sometimes you think, how come I didn’t know about this back then? But I feel like it’s a process. Dr. Deb Muth 12:06It definitely is a process, and it’s amazing to seehow many people are researching different things, and they’re all, like, putting a piece of the puzzle together. And I think this is really important for our listeners to understand, is when you see a practitioner and they don’t have all the answers, this is why. It’s very complicated, it’s not black and white. And I’ve had patients over the years say to me, well, why didn’t you say this to me 6 months ago? And the truth of the matter was, I didn’t knowabout it 6 months ago. Like, all of this stuff is just… it’s evolving constantly, and when you’re a practitioner like Dr. Usman and myself, you are learning every single day. Our training has never stopped from the day we stepped into integrated medicine, and you just… you keep learning new things, and sharing new things, and talking to new people, and that’s what expands our knowledge base. Anju 12:57Yeah, the more I learn, the less I feel like I know. Dr. Deb Muth 13:01Yes, me too. Every time I go to a conference, I’m like, how did I not know this? How am I stupid? And I know we shouldn’t say that word and call ourselves that, but sometimes you feel like that. It’s like, how did I not know? Anju 13:14Or you’ll see a patient, and you’ll look at them, and you’re like, how come I didn’t realize this about this particular patient? Dr. Deb Muth 13:20Yes. Anju 13:21Yeah, they present differently, see things differently. I think that’s why it’s good to find a doctor that you trust and that you can work with, because it’s evolving. Dr. Deb Muth 13:31Yes. And, you know, we have those patients that they come, and I get those. I call myself, like, a tertiary care center. Anju 13:38You know, you get those patients that have been everywhere, and seen every doctor, and then they’re like, you’re my last hope, you’re gonna solve all my problems, and…I say to them. We’re a team, like, we’re gonna solve these together, but it takes time for me to unravel this puzzle. Dr. Deb Muth 13:54Excuse me? Anju 13:54And it… and sometimes, you know, there’s a few hits and misses along the way. Dr. Deb Muth 14:00Yup, but if. Anju 14:00If we keep at it, you know, we also say it’s a marathon, not a sprint. Yes. You know, if we keep at it, we can kind of figure it out together. Dr. Deb Muth 14:09Yeah, and a partnership, for sure, because without the feedback of the person you’re working with.understanding, like, we do this, and this happens to you, it’s very complicated as a practitioner to then be able to figure out, what do we do next? I see more and more clients these days, they come in and they just want to ask me within the first 5 minutes of, what am I changing? And I’m like, I have no clue yet. Like, you have to tell me what’s happened since the last time we did something, and then we have to look at labs, and we have to look at this, and we… it’s a synopsis.that we have to look at. You know, it’s not that black and white for us to be able to put the pieces together for them. Anju 14:47I think my most successful patients are the ones who are able to communicate with me.Their ups and downs. Yeah. And they also use their own intuition. Help me guide them. Dr. Deb Muth 15:06Yeah. Anju 15:07So, there are some people that they just hear, you do it, and you tell me.There are people who try to tell me everything. Dr. Deb Muth 15:15Okay. Anju 15:15Say, I want you to do this, do this, do this. Dr. Deb Muth 15:17Yeah, so I was like, okay. Anju 15:19I can do those things, but, you know, like. Dr. Deb Muth 15:21Yep. Anju 15:22think about blah blah. But, like, this… that collaboration.and, intuition. I kind of feel like even thoughI’ve trained allopathically as a traditional medical doctor. I feel like as I learn, I learn that being open and,Letting go of fear. Dr. Deb Muth 15:46Yeah. Anju 15:47And, not trying to jump on every, like, new thing, and being. Dr. Deb Muth 15:53consistent. Anju 15:54and diligent. really helps. Dr. Deb Muth 15:58It helps a ton. We see that, too, you know, the latest…Instagram influencer that’s talking about the latest topic, and all of a sudden, everybody sees themselves in there, and they must have that, but not realizing putting those connections together. It’s like when MTHFR came out, right? We were all so excited that this was going to be the detox gene.And then we learned so much more about genes, and now MTHFR is very popular again, and everyone’s talking about it, but they don’t understand how some of those other genetics fit together. And if you don’t understand that, we’ve all done it, we’ve all made people worse instead of better, sometimes when we’ve given too many methyl groups together, or this supplement without this support before we knew that there was another gene that we had to support for that.And I think it’s really important for people that are listening to us today talk about this, is don’t just jump on the bandwagon. Like, you really want to work with somebody seasoned who understands how all these pieces fit together. Anju 16:57Yeah, and I think that’s what individualized medicine is about.And there is no magic here, a magic bullet.I think that example of MTHFR is really good. Now, President Trump talked about Leukovorin. Dr. Deb Muth 17:14Yes. Anju 17:15in, and, you know, he’ll get up and say something like, leukovorin cures autism.And then the rest of us are like…Did you just say that? Dr. Deb Muth 17:26Yep, he did. Anju 17:30It’s folinic acid, it’s calcium folinic acid, it’s been around a long time. We’ve been using it for 20 years. Dr. Deb Muth 17:37Yeah. Anju 17:38But it does help a subset of people who potentially have what we call cerebral folate deficiency.And some of those people are misdiagnosed as autism. Dr. Deb Muth 17:50Yeah. Anju 17:51So, are you treating autism, or are you treating cerebral folate deficiency?same thing I could say about… I have a lot of cases of kids who recovered from autism.and severe ADHD using chelation type of. Dr. Deb Muth 18:06up. Anju 18:06Approaches, or detox approaches.again, did we treat their ADD and their autism, or did we treat their lead…Toxicity or lead burden, and their symptoms of those things got better. Dr. Deb Muth 18:20Yeah. Anju 18:20So, like, to put a big, like, a label like, oh, ADD on something, or autism on something, I think it does a disserviceTo the individuals, because it’s such a broad issue. Dr. Deb Muth 18:35It is, and I think the diagnosis has gotten to be much more popular these days.And yes, thank goodness we’re getting better diagnostics, but sometimes we’re getting over-diagnosis, or like you said, it may look like one thing, but it could be something else, but because it looks like autism, they’re going to get labeled with autism.And in some respects, that’s good, they can get more services that way, but sometimes we’re missing the actual picture of it. Can you talk a little bit about how autism is different than the cerebral folate deficiency? Anju 19:11Yeah, so there are some people that make an antibody to their folate receptor. Dr. Deb Muth 19:18Hmm. Anju 19:20So, to get folic acid into your cells, there’s a receptor on your cells. Dr. Deb Muth 19:25And then the folate has to bind to it, and then it lets it enter into the cells. Anju 19:30And there’s these receptors that allow folic acid to get into your brain.Now, you and I know when you put folate in your brain.On one end of the folate cycle, you help make more neurotransmitters. You’ll make something called BH4, and that’ll help make serotonin and dopamine, and then norepinephrine and epinephrine. So folate is really important for making your neurotransmitters, folate and B12.On the other end, it’s like, another cycle on the other end of folate is our methylation cycle.And methylation is so important for our RNA and our DNA, and making choline, phosphatoly choline, and making creatine for speech.And helping us with all the precursors for detoxification.So without folate in our brain, we can’t make our neurotransmitters efficiently, we can’t break them down efficiently, and we can’t detox our brain.Imagine what that will do to your brain. Dr. Deb Muth 20:36Yeah, Anju 20:37And you will see symptoms like speech delays, cognitive delays, processing issues, poor attention.All of those things. Excitation, anxiety.All of those, and so if the folate isn’t getting into the brain efficiently, then we’ll have all these symptoms, and we’ll end up with diagnoses like these. Dr. Deb Muth 20:59Yeah, so is there a way that people who are listening to this can request a test to see if they make this antibody to folate, or is it more of a diagnosis of exclusion? Anju 21:14That’s a great question. When I first started doing this, like, 20 years ago, there was, like, a university that was doing this.studies, and it was Dr. Quadros. He was the guy, and we would take samples and send them to his lab, and he would tell us about these blocking and binding. Dr. Deb Muth 21:30folate antibodies. Anju 21:32And if patients had positive blocking or binding folate antibodies, we would follow his protocol. And he’s done papers on patients with severe autism.Where he found these folate antibodies, and then did spinal taps on the kids, and they were associated with this cerebral folate deficiency. the cerebral… spinal fluid.And in his papers, he gave .5 to 2 milligrams per kilogram of calcium folinic acid, which is leukovorin. It’s a vitamin. And over a 6-month to a 12-month period.The majority of those patients improved drastically.Some of them regained speech, and some of them lost their autism diagnosis. Dr. Deb Muth 22:26Because they never truly had autism. Anju 22:29Well, they have autism symptoms, and that’s what autism is, but we call it autisms. Dr. Deb Muth 22:36Yeah. Anju 22:37And so now, like, we need the research to categorize these people. You know, what percentage of autism is cerebral folate deficiency? Yeah. What percentage of autism is, heavy metal. Dr. Deb Muth 22:51Bourbon. Anju 22:52And what percentage of autism is Clostridia overgrowth, or… Dr. Deb Muth 22:57Hmm. Anju 22:57microbiome… Dysfunction, and then there’s overlap. Dr. Deb Muth 23:01Right, yeah, Lyme and mold and viruses. Anju 23:04and infections, and you can see… Dr. Deb Muth 23:07injury from medications and things like that that happen, or birth traumas. Yeah, I mean, it’s not… it’s not as simple as what people think autism is.Why do you think that we’re seeing so much more autism today than when you and I were kids? We didn’t see this that often. I know environment has a lot to do with it, but do you have a couple of things that you suspect are contributing to the rise of autism these days? Anju 23:38Yeah, I mean, that’s a million dollar question. Dr. Deb Muth 23:40Right. Anju 23:41And, just because I work with children, you know it’s not just autism that’s epidemic, and yeah. Dr. Deb Muth 23:49You know that. I mean, it’s… it’s probably… if you add all the epidemics that are happening to children. Anju 23:54Autism still supersedes it.Now it’s 1 in 33s, 1 in 35 boys, I mean, it’s…children. It’s really sad. When I was in med school, it was 1 in 10,000. Dr. Deb Muth 24:10That’s crazy. Anju 24:11What’s causing it? I mean, obviously it’s multifactorial. Dr. Deb Muth 24:15Yeah, 80,000 chemicals in the environment that we never had before. Anju 24:20I, I, I, look, I’ve… 219 million. Dr. Deb Muth 24:26Oh my gosh. Anju 24:27I looked it up today. Dr. Deb Muth 24:29119 million different chemicals in the environment. Wow. Anju 24:33We don’t know how many of those are super toxic. Dr. Deb Muth 24:36Yeah, and we don’t know what they do together. Anju 24:38A lot of them were, like, before, like, grandfathered in and all of that.Yeah, it’s really crazy about the chemicals. So, chemicals… I kind of… feel like…you know, this burden of all this, it’s not just on our children, it’s on our mothers. Dr. Deb Muth 24:56Yes. Anju 24:56oh my gosh, the moms of these children that… And they don’t even realize it, you know, we’re just so happy to be pregnant and have a kid.So I think it really, really starts with that piece. Care, good prenatal care, yeah. Yeah, and not just what we think is prenatal care, taking your prenatal vitamins. Dr. Deb Muth 25:18Yes. Anju 25:19And going to your gynecologist, but what you and I think is prenatal care, you know, before you get pregnant, let’s detox, let’s clean up our diet, let’s get rid of those chemicals, let’s make sure we’re not in a moldy environment.You know, let’s do our due diligence, clean air, clean water, clean food, sunshine. When I did my residency at county, I don’t think I saw the sun for 3 years. Dr. Deb Muth 25:44How?Yeah. Anju 25:46it’s just that intense, and I was pregnant twice, and my eldest hasthe allergies and asthma. Number 2 is type 1 diabetes and mold sensitivities and allergies and asthma. Number 3 has severe chemical sensitivities, mast cell activation,Hormonal issues. Dr. Deb Muth 26:09Yeah. Anju 26:09And… number 4 is my… Golden, baby. Dr. Deb Muth 26:15And those three, you know, those years that you’re there, and you’re not seeing the sunlight, there’s vitamin D deficiency, and we don’t talk about vitamin D that much during pregnancy.I still am appalled that we’re giving folic acid these days during pregnancy instead of folate, but… Anju 26:36Folenic, or methylfolate? Dr. Deb Muth 26:38Yeah, nothing. So, when, when you,discovered vitamin D in pregnancy, and it’s linked to neurodevelopment outcomes. How did you stumble across that? Anju 26:50Well, in… when I started working on Copper Zinc, Dr. Walsh and I would go to the, like, DAN conferences.Yeah. At the time, and it was interesting, because DAM conferences were a collaboration between parents.And practitioners, and researchers. Dr. Deb Muth 27:10Very unique for. Anju 27:11That’s how that new IACC committee is. It’s a collaboration of parents. Dr. Deb Muth 27:17Hmm. Anju 27:18Practitioners, researchers, And individuals with autism. Dr. Deb Muth 27:25Yeah, so for those of you who are listening to us, it’s… we’re talking about the Interagency Autism Coordinating Committee that Bobby Kennedy just put together. It’s called IACC, and they are on a mission to try to do the research to figure out what’s causing autism. Anju 27:43Yeah, and not just causing it, like, these people have been living it, most of the people on that committee have been living it, and their whole lives, for some of them.And being able to bring forwardlike the question about vitamin D, we started seeing a lot of patients in Minnesota. Dr. Deb Muth 28:04Mmm. Anju 28:05who were from Somalia. Dr. Deb Muth 28:08Okay. Anju 28:09Who were… it was, like, 1 in 4 families with kids with autism.And the theory was that the vitamin D levels that they get in Somalia versus the vitamin D levels that the moms get in Minnesota. Dr. Deb Muth 28:27Hmm? Anju 28:28Affected the immune system. Dr. Deb Muth 28:31Yeah. Anju 28:32predispose them. So there’s a few papers on that. Dr. Deb Muth 28:36Yeah, that’s a… I mean, it would be a very significant difference, and when you’re thinking about genetically, like, what their culture, who they are as a species.was used to and adapted to with the sunlight and different things from a different region, geographical region, and then they moved to a new geographical region, that can take decades before the body adapts and readjusts.to that new environment. We don’t think about those things in…traditional medicine, and conventional medicine, as most people know it, but we do in functional medicine. Anju 29:14Yeah, so again, the clinicians were bringing this up, like, why am I seeing so many families? Dr. Deb Muth 29:18Yeah. Anju 29:18Then let me go to the… and then in the think tank, the vitamin D researcher said it’s vitamin D. Dr. Deb Muth 29:24Yeah. Anju 29:25And then they started researching it, and it was almost like a backwards… backwards. Dr. Deb Muth 29:31Thank you. You know, they didn’t first… Anju 29:33Think it. Dr. Deb Muth 29:34Think about it, yeah. Anju 29:35Until you start seeing… and that’s why I think that, like.clinicians like you and me, who are… I consider us on the front lines. We’re the front lines. We are seeing… we’re seeing this epidemic unfold. Dr. Deb Muth 29:46Yes. Anju 29:47front of our eyes, we’re seeing, like, the gut issues and the severe inflammation. We’re seeing the autoimmunity, and now they have to study it. Dr. Deb Muth 29:57Yeah. Anju 29:57They have to study this. They really, really, we really need, we really need protocols, we need tools, we need things that you and I have been figuring out anecdotally with our colleagues over the years, and, oh, how do we treat yeast? How do we treat Lyme? How do we treat metal burden?For this podcast today, I wanted to talk about low-level lead exposure, because for me.1 in 3 children have a lead level, above 5. 1 and 3. Dr. Deb Muth 30:31Yeah, that’s very high. Anju 30:33800 million children. Dr. Deb Muth 30:36And let’s clarify this, because the first thing people are going to think of is, what are they eating? They’re not eating lead paint to get this. That is not what’s happening here. They are getting lead from someplace else, and their bodies are not able to detox this. Anju 30:53And the reason I’m bringing this up is because when I was in residency at County in the 90s, I ran a… I worked at a lead clinic. Dr. Deb Muth 31:01And back then. Anju 31:03When we looked… we just diagnosed lead toxicity, the level was 60. Dr. Deb Muth 31:10Their level had to be 60 to diagnose them. Anju 31:13Correct. Dr. Deb Muth 31:13Oh my gosh. Anju 31:14And that’s when we would treat.And back then, there was a study, it’s called the TLC study, where they used DMSA, which is a drug to lower lead.And our goal was to get it from 60 to 20. Dr. Deb Muth 31:33And was the normal range the same back then as it is today? Anju 31:37The normal range has gone from 60 to 40 to 20 to 10 to 5 to 3.5.But you and I know I’m the normal range. Dr. Deb Muth 31:47Yes. Anju 31:47Zero. Dr. Deb Muth 31:48Zero. Anju 31:50So… so again, in my… in the lead clinic, we were given DMSA, and we got the lead from 60 to 20, and the number one thing was to get rid of the lead in the environment. Dr. Deb Muth 32:02Yeah. Anju 32:03But we haven’t evolved since then.Because in that study, It did not improve cognitive abilities. So if you think about what lead does, it causes attention issues, slow processing, it affects hearing, it can cause hyperactivity, it can cause impulsivity, it can cause aggression, it can cause constipation, it can cause hypotonia.So if you think about all these kids with ADD and autism, how many of them have low-level lead exposure from the lead pipes? In Chicago, it’s a big, a big problem. Dr. Deb Muth 32:37Yeah, Milwaukee. Anju 32:38Everybody thinks Flint, Michigan, but Flint, Michigan is not the only place. Dr. Deb Muth 32:42Right. Our infrastructure is so terrible, it has not been updated, and even though you might look in your house and you might see a white PVC or plastic pipe, what’s coming under the ground to the house in the cities is usually still lead. Anju 32:58Right. Right. Dr. Deb Muth 33:00Yeah. Anju 33:01So, I guess the point is, is that…the… the idea of, like, studying this. So, again, they study this, and they say, well, we’re not going to treat low-level lead exposure because it doesn’t improve their cognition.But did they really treat it? Dr. Deb Muth 33:18Right. We got it from 60… we got it from 60 to 20. Right. But when I know, where is the lead hiding? Anju 33:24So high. Look at the bones, it’s gonna be coming out. It’s gonna be coming out, especially during puberty. What happens to some of our kids during puberty? They just go a little wonky. Comes out again during menopause. Dr. Deb Muth 33:38Yes. Anju 33:39I don’t know, male menopause, too. Like, we’re all losing bone mass then, and our lead is coming out, our blood pressure goes up. So, again, these are some of the areas that I think, like, really need some… hard… looks. Dr. Deb Muth 33:53Right, yeah. So, what are you hopeful about this committee? Like, are you hopeful that this committee is going to be able to research some of these big things, and we’re really going to be able to find answers around some of the functional things and the biochemical things that we see, you and I know happen in the body, that might give some standardization and education to practitioners in the future. Anju 34:23Well, I think this committee understands the scope of the issues.And they’re coming from different perspectives, like I mentioned, research. Dr. Deb Muth 34:33Yeah. Anju 34:35really highly qualified MDs. MDs like you and me, who have been on the front lines. moms. Dr. Deb Muth 34:43Yeah. Anju 34:44dads, patience, And so, the strategy would be to get, again, their input, and then…get the places… people in places to do their research. And even make some guidelines and some, like, you know, thoughts about what we want to put out there. Dr. Deb Muth 35:05Yeah. Anju 35:05You know, how do we want to strategize for… Dr. Deb Muth 35:08Prevention. Anju 35:10Like, the pre-pregnancy thing. Dr. Deb Muth 35:12Yeah, I’m really hopeful that this doesn’t become a… political football,And it doesn’t get taken away if the administration changes or whatever, because people need to understand that this kind of researchthis is going to take decades for people to do. Granted, we have AI, and AI can help a little bit and get some things quicker.But trying to figure out all of these nuances to why the body does what it does is not gonna be, like, next week we’re gonna find out that this was the single cause, and I know a lot of people, they’re afraid of the vaccines, and that’s gonna be the sole answer.And that has a piece of it, but it is just a small piece of it for some people larger, but at the end of the day, that’s not what this is about. This isn’t about just labeling one thing that is the cause of autism, because it is not one thing. It is so multifactorial. Anju 36:09And I think that whole cause, I know,A lot of money has gone into. Dr. Deb Muth 36:16Yeah. Anju 36:16looking at that. They’re looking for the gene, right? The gene that causes it, and… Dr. Deb Muth 36:23answer. Anju 36:24They have not… they’ve spent millions of dollars looking for this.And it’s not gonna pan out. It’s not. Dr. Deb Muth 36:33I’m not. Anju 36:34pan out. It’s more complex, like we’re talking about. Dr. Deb Muth 36:38Yeah. Anju 36:38And, I do think that sometimes, you know.Even though, like, politically, it seems like it’s a political topic, but it has zero to do with politics. Dr. Deb Muth 36:52Yeah, exactly. This is our children. This is the future of our country, the world. I mean, America’s not the only place that has kids with autism. I mean, this is the future of humanity. If we don’t figure out what’s injuring our children, there will not be a humanity that you and I have seen. It will be different. And, and this is important, we owe it to the future of our generations, we owe it to our children to figure this out and clean up our environment, and make it safe for everybody. Anju 37:24Yeah. Clean up our air, clean up our water, clean up our food… Dr. Deb Muth 37:29Yeah. Anju 37:30You know, our lifestyle a little bit, but… Dr. Deb Muth 37:32hoodie? Anju 37:33It’s… it’s… it’s everywhere. I travel all over. Dr. Deb Muth 37:36Bye. Anju 37:37Consult with doctors in different countries, in Italy, in India, Bulgaria, Romania… Dr. Deb Muth 37:46Yeah. And. Anju 37:48we’re going to Australia for med maps to treat doctors in, in April. And it’s a problem everywhere. Dr. Deb Muth 38:00Yeah. Anju 38:01really big problem, and it affects everybody. Even if you don’t have a child with autism or a grandchild with autism, it’s still affecting families, becauseI kind of think of ADD as being on the spectrum, in the sense thatI think the same kind of positive issues that lead to the autism are causing the ADD, just to… you know, your genetics are playing a little bit of a different role, whatever… whatever protection you have is a bit more there, but we’re seeing kind of, like, similar metabolic… issues in our ADD population. Dr. Deb Muth 38:43Yeah. Yeah, there’s so many different levels of this, and it does affect everyone. Like, I think everybody knows… a family or someone in their classroom or their school or their community that’s affected by, definitely, ADHD, Asperger’s, autism, all of those things, whether you’re high functioning or not functioning or whatever.everything is affected. The school system is affected, your social circles are affected, your families are affected.the healthcare is affected. I mean, everything is affected. We owe it to our families and our communities to help people try to figure this out. Anju 39:22Yeah, and I think even if it’s not ADD, or ADHD, or autism we’re talking about, or even OCD, anxiety, depression, I mean, you know… Dr. Deb Muth 39:33Candace? Anju 39:34Any kind of chronic illness that people are dealing with has underpinnings of these kinds of, you know, issues. Dr. Deb Muth 39:43Yeah. Anju 39:44Any autoimmune issue? That’s great. Dr. Deb Muth 39:48inflammatory syndrome that we’re seeing these days, I mean, the pants-pandas piece, the biofilms, the strep, I mean, our environment is just so laden with infections and biofilms, and And, you know, when you and I first were learning about this, we never thought anything could cross the blood-brain barrier, right? It was pristine, there’s nothing getting in there unless you could drive it in there, and now we know that’s different, and now we’re seeing bugs in the brains of people who have had Alzheimer’s disease and dementia because they’ve donated their brains for research, and we can see what’s crossing the blood-brain barrier, and it’s really scary. Anju 40:24Yeah, yeah. There’s a lot of things we don’t know. Remember when we just found out that they… the brain had a lymphatic system? Dr. Deb Muth 40:33And that wasn’t About, what, 5, 6 years ago? 7 years ago, maybe? Yeah, not that long ago. Anju 40:38You’d be like, why wouldn’t the brain have a lymphatic system? Dr. Deb Muth 40:41Yeah! Yep. Anju 40:44Yeah, so things get in and out. Dr. Deb Muth 40:46They, they definitely. Anju 40:47You know, they get in easier than they get out, I think. Dr. Deb Muth 40:50I agree, I think they do, for sure, for sure. You know, when you’re talking to a family who’s undergoing issues like this, what’s the role, do you feel, in personalized nutrition to help them make things better? Anju 41:10I kind of go through, like, a little bit of a start here, start there, and then do this. I always start, number one, I say, okay, you gotta clean up your environment, because… We gotta do that. Dr. Deb Muth 41:24But that’s a… Anju 41:24process. And then number 2 for me is cleaning up the diet. And then, when you say personalized nutrition. To me, figuring out what is a good diet for the individual. Dr. Deb Muth 41:38Makes it a little bit difficult. Yeah. Anju 41:41I mean, there is, like, healthy eating concepts, where, you know, eat upside-down food pyramid kind of concept, I guess, is the new one, but whole foods, whole grains, organic as much as possible, especially for animal products, good fats, avoiding, you know, hydrogenated oils, and those seed oils, and… Just some basics, and then individualizing for my patients, a lot of people with any kind of autoimmune condition, and we kind of put autism in that neuroimmune, autoimmune, inflammatory That, gluten-free, dairy-free, and sugar-free kind of go there, like, as a given. If there’s a lot of gut issues, a lot of our folks have oxalate issues. And then we have to sometimes do low or limited oxalate diets. Many of my patients can’t convert glutamate to GABA efficiently. Dr. Deb Muth 42:44Yeah. So, high glutamates associated with OCD, and kind of looping or repetitive behaviors. Anju 42:51So, low-glutamate diets. And then some of my patients have SIBO, and then we do the low FODMAPs diet, and then some of my patients have messel, and we’ll do the fail-safe kind of concept with the fail-safe diet, so nutrition can get a little bit complex for certain people, but there are some basics, and then there are some, like, more of… Individual, kind of, diet approaches. And then there’s supplementation. There’s some things that I call foundational. For me, certain things most people need that have a chronic illness. Dr. Deb Muth 43:26Yeah. Anju 43:26Vitamin D3 is one of those. Omega-3s are another one for most. And then, because I did a lot of research on copper, zinc, I think 3 mineral… 4 minerals. I feel like people underdo minerals. They’re so important. Every single enzyme has a mineral cofactor, so… zinc is really important for my population with autism and ADD. 99% of them had high copper or low zinc in. Dr. Deb Muth 43:58Wow. Anju 43:59Over 400 patients that we tested. Dr. Deb Muth 44:01Wow. Anju 44:03And, magnesium.So, zinc, magnesium, and then the other two minerals I really like are selenium for glutathione. and molybdenum for sulfation, and glycolysis. So… So those are kind of my foundational pieces, and then I like to work on the gut next. So, from a nutritional perspective, prebiotics are my new favorite. Dr. Deb Muth 44:29Yeah, we go in and out with prebiotics, probiotics, postbiotics. Anju 44:34Yeah, exactly, symbiotics. Dr. Deb Muth 44:36Yes, exactly, exactly. Anju 44:38demos, and… Dr. Deb Muth 44:40Yeah. Anju 44:40So yeah, biofilm busting, and all of that, so… And then I go into my other nitty-gritty stuff, like you probably do. Dr. Deb Muth 44:47individualized, right? So, you created, True Healing Nature, a supplement line, a supplement company, correct? Anju 44:56Yeah, True Hing Naturals. Dr. Deb Muth 44:58Truly Naturals, okay. Anju 44:59True, he is hard. Dr. Deb Muth 45:01Oats! Anju 45:01True! Dr. Deb Muth 45:01Healing natural. Got it, sorry about that. Tell us a little bit about what made you decide to create a supplement company. Was it because you couldn’t find formulations that you wanted? Couldn’t find clean products? That’s a big problem for people, for sure. Anju 45:19Yeah, a little bit of both. I told you that my kids were really sensitive, they had a lot. Dr. Deb Muth 45:23I know. Anju 45:24And when I would even try to give them things like ibuprofen. Dr. Deb Muth 45:28or Benadryl. Anju 45:30For allergies, they couldn’t tolerate the products that were over-the-counter. Dr. Deb Muth 45:35Yeah. Anju 45:35So, in 2007, I opened a compounding pharmacy so I could make things clean for them. Dr. Deb Muth 45:42Yeah. Anju 45:43And I thought it was so valuable. And so then I started seeing, like, certain issues with my patient population, for instance, say, mitochondrial issues. So, I would compound a mito cocktail. in my pharmacy. And then I had True Healing Naturals manufacture it, so I didn’t have to have patients get it compounded. Dr. Deb Muth 46:08Got it. Anju 46:09So that particular product’s called Mito Rescue. Okay. But then, I started… I do a lot of oats testing. Organic acid urine tests. Dr. Deb Muth 46:19Yeah. Anju 46:20But there’s, like, a marker on there for, oxalates, and I saw a lot of patients with oxalates, and oxalates inhibit some… an enzyme called, pyruvate decarboxylase. And that basically means you can’t take your carbs and turn them into energy. Dr. Deb Muth 46:38Okay. Anju 46:39So, if I saw this pattern with high oxalates and high pyruvic acid, I knew that that enzyme wasn’t working very well, and that enzyme is B1, molybdenum, and biotin dependent. So, I started compounding doses of that. And then I turned that into a product called Motor Connect, because high doses of biotin help with connectivity in the cerebellum. Dr. Deb Muth 47:08Got it. So, I did come… kind of start with the compounding pharmacy, try it, use it, and then turn it into. Anju 47:17products, and I have one for copper-zinc imbalances called True Minerals. Dr. Deb Muth 47:21Yeah, to fix the problems that were not commercially available. Could you talk a little bit for people who don’t understand what a compounding pharmacy is? Anju 47:32So, when you guys go to a pharmacy, you, you know, you send a prescription, and it’s already, it’s manufactured, and you get it. Well, a compounding pharmacy actually makes that for you. So they get the raw ingredients, and then they make that prescription. So it’s still prescription-based. But, for instance, say, I want Nystatin. And I go to Walgreens or CVS, and the nystatin there is a liquid, and it has yellow dyes and sugar. Dr. Deb Muth 48:02Yep. Or it’s a title, and it’s red. Anju 48:04or it’s bread, and a tablet, and I, like, oh, I want to treat the yeast, but I don’t want to use this. So I sent my nystatin prescription to a compounding pharmacy, and it’s Nystatin. That’s what you got. Yep. Dr. Deb Muth 48:17disappear. Anju 48:18So, pure compounding pharmacy, it’s pure, it’s pure stuff. Especially for our mast cell people. They’re so sensitive, and, you know, my kids are all mast cell, and so I just find that excipients, some people will say, oh, this doesn’t work, and I said, it’s probably the excipient that’s stimulating your mast cell activation. So, yeah. So, compounding pharmacies, You know, with all the big, kind of. conglomerates and big companies, they’ve become… they used to be, like, mom-and-pop kind of places. And my pharmacy is like that. It’s just… it’s… it’s a few of us, and we… we do it, and it’s nothing big or fancy, but we get the job done. So, we compound things like methylcobalamin injections, hydroxycobalamin, low-dose naltrexone. Different things for chelation. So, it’s nice. I love having it. Dr. Deb Muth 49:11Yeah, the compounding pharmacies really have made a huge difference for people who are sensitive. You know, so many ingredients are contaminated with corn and gluten and soy and dairy and all the big things that we want to stay away from, especially if we’re trying to treat the immune system. And even if the manufacturer says that’s not in our product. it’s contaminated, usually, because they’re usually preparing it in a facility that has those things floating around. Right. And for people who are really sensitive, that’s going to create some issues. Anju 49:45Yeah, people who are sensitive are sensitive to parts per trillion. Dr. Deb Muth 49:48Yeah. Anju 49:49I found that with my daughter with chemical sensitivity. You don’t have to see it, or you don’t have to smell it, but they could react to it. Dr. Deb Muth 49:55Yeah. And, a lot of these, like. Anju 49:58These different, substances, for instance, like enzymes, even the natural enzymes. Dr. Deb Muth 50:03They’re cultured in Aspergillus. Anju 50:07And so they’re extracted from mold. Dr. Deb Muth 50:10Yeah. Anju 50:11And so the really mold-sensitive people will maybe take a digestive enzyme, and they’ll have a reaction, and they’ll not understand why. Yeah. But it’s not because of the enzyme, it’s because of where it’s coming from. Dr. Deb Muth 50:22Yeah, where it’s cultured from. And if you have mold toxicity and mold sensitivity, and we’re looking at your mold test, wondering why are you getting a hit while we’re trying to clear it out, sometimes we forget that those products, and a variety of products that we used are cultured from molds. Yeah. Anju 50:40Yeah, yeah. It’s hard for the laypeople to understand all. Dr. Deb Muth 50:45You know. Anju 50:45of these pieces, but I think that… It used to be, like, the insurance companies would cover prescriptions from compounding pharmacies, but over the years, the lobbying and all of that has gotten so intense where, you know, a lot of that ends up out of pocket, but it’s really… it doesn’t really get that much more expensive than a copay would be. Dr. Deb Muth 51:05Right, right. Anju 51:06People just don’t know about it, yeah. Dr. Deb Muth 51:08Yeah, absolutely. So, you’ve been doing this now for more than 17 years, and you’ve made some remarkable progress with your patients. Can you share some success stories that still inspire you to do what you do every day? Anju 51:27I don’t know about you, but, like, when you first start, I think, God puts you… God puts all those really gray cases in front of you, because you’re like, whoa! Dr. Deb Muth 51:37Yes, and maybe… Anju 51:38I gave this patient methylcobalamin, and they started talking. Yeah. So methyl B12 back in the day was huge. you know, Dr. Nebrander’s protocol, and we would use that, and we would get speech, and… I mean, I’ve… it’s just… there’s hundreds of cases. There’s hundreds of cases, and same with Leukovorin now. Not for everybody, but when it really works, it’s really, really decent. Dr. Deb Muth 52:07Yeah, and worth a try, you know, if… if we suspect that’s what’s going on, these things are worth a try, because sometimes you just never know what’s going to be the key that unlocks the answer for them. Anju 52:19Yeah, but I think, you know, like, I can say… chelation, or… you know, I can, like, throw out a bunch of stuff. Dr. Deb Muth 52:26Okay. Anju 52:27In terms of, like, I’ve… I… I have those families, and I have those kids who are just… they’re just amazing, and they’re in college, and having jobs, and having kids, and… Dr. Deb Muth 52:38Yeah. Anju 52:38you know, all of that, but I think, you know, the ones that really strike me are the ones that I have to work really hard to get. Dr. Deb Muth 52:44And then we’. Anju 52:45they go, it’s not like, oh, I just did the diet, I’m cured, or I did this, and I’m better, or… Right. And I have those cases where the parents come to me and they say, I never thought my kid would Be going to college. And I never thought we would be here. So, those are the ones that really, like, when I get the little notes, or the, like, the college or the high school graduation pictures, and they… and some of them, you know, you lose touch with because they don’t need me anymore. Dr. Deb Muth 53:19Yeah. Anju 53:20And then you hear about it later. And then, I think the ones that don’t get better are the ones that, like, sit with me the most They just sit with me, and we’ve had this population of children with severe apraxia. So, apraxia is a motor planning issue, but if you saw these patients, you would think that they were… mentally deficient. Dr. Deb Muth 53:44Hmm. Anju 53:45Because they can’t talk. Dr. Deb Muth 53:46Yeah. Anju 53:47They’re the classic person that you would see that looks autistic. You know, running around, excited, verbal stimming, no speech. Dr. Deb Muth 53:57Hmm. Anju 53:58And that group of patients are incredibly Brilliant. And we are just finding out about how smart they are. There’s a book called Underestimated by J.B. Hanley and his son Jamie. JV has all the resources in the world. He used to put those ads in the New York Times about autism and vaccines. He could take his kid anywhere and do any treatment, and still, we… Blocked. Locked. Couldn’t get through. Couldn’t get through. And they started, spelling. To communicate, and this speller’s method, and it just opened a door. And it opened a door for so many of my patients who are metabolically challenged, so we do help them metabolically. Getting that ability to communicate. Some of them never got high school diplomas, and they went back to get their high school diplomas so they could go to college. Dr. Deb Muth 54:56Oh, wow, that’s amazing stories. Anju 54:59Yeah, and Elizabeth Bonker is one of those spellers, and she… she was a valedictorian in her high school, college. And she did a valedictorian speech that went. Viral, and she’s one of the people on that committee. Dr. Deb Muth 55:13That’s awesome. Anju 55:14He’s non-speaking. She… she can’t not speak. Dr. Deb Muth 55:20Wow. Anju 55:21But they asked her to be on this committee. Dr. Deb Muth 55:24That’s fantastic. Anju 55:26Huge. Dr. Deb Muth 55:27That’s huge. It is huge. There’s a way she can communicate, she just can’t verbalize the way you and I verbalize. Anju 55:34She’s brilliant. I mean, people on that committee, the, the individuals with autism on that committee, I know they’re brilliant people. Wow. But if you… if… If people saw them, they wouldn’t see that. Dr. Deb Muth 55:47Right. Anju 55:47So, I guess, for me, it’s like seeing the brilliance, seeing the competence in individuals, and as a practitioner, just trying to optimize it. But I know, like, the neurodiversity people say, okay, you know. We’re fine, and it’s like, yes, you are fine, you’re fine, and it’s okay. Whatever it is, it’s okay. But if you’re struggling metabolically, and we can help you feel better. What’s… what’s the harm in that? Dr. Deb Muth 56:13Right, let’s do that. Yeah. So you’re also part of something called MAPS, and you’re educating doctors worldwide. Tell us a little bit about MAPS, and how do you see the integrative pediatrics evolving in the next decade as a result of what we’re learning today? Anju 56:36I think we’re at a crossroads, and Maps is kind of in the middle of that crossroads. It used to be called Dan. Dr. Deb Muth 56:47Okay. Anju 56:47Autism Now. Dr. Deb Muth 56:48Yeah. Anju 56:49And then they kind of dissolved Dan and turned it into MedMaps. And MedMaps is Medical Academy for Pediatrics and Special Needs. So it’s not just special needs, it’s pediatrics. as well.So it’s kind of like the functional medicine for peds. And our goal is to train an army of clinicians to be the frontline. And how medicine should be, and how people should be trained. We should train them to do these types of things from the beginning. Because now it’s backwards. Dr. Deb Muth 57:28Right. Anju 57:30they come see us when nobody else can help them. But, so, we have some good leadership, and then… We are just trying to get people trained so that they understand that this is the future. Dr. Deb Muth 57:50If there’s a practitioner that’s listening to this, how do they get involved in MAPS? Anju 57:55They could come to a conference. Dr. Deb Muth 57:57Okay. Anju 57:58And the website is medmaps.org. And there’s 2 conferences a year. And we have scholarships, and we want people to come, so contact You know, the executive director, and… We just want people to come, share… their experiences, learn about functional medicine, it’s evidence-based, we try to… it’s really scientific, you know, we talk a lot of science. Dr. Deb Muth 58:25Oh yeah, a lot of science. Anju 58:26We talk a lot of science, and and so hopefully we can move all of this forward. Baster. Dr. Deb Muth 58:35I think the greatest thing, when you get into the functional medicine integrative space like this, and MAPS, and some of the other environmental academies and things like that. A lot of people might think it’s not science-based, and I’m always amazed at how much science we have, and it’s right, it’s all the things that you and I learned in biochem class, and chem class, and organic chem, and we were like, oh, let’s just learn this to be done with it. And then you get back, and you start doing integrated medicine, and you realize, like, all of that biochemistry stuff is what we needed to truly understand to fix people these These days, and you go back and you have to learn that in an intense version of it. Anju 59:18I felt like I finally understood the Krebs cycle, when I learned how it made metabolic stents, instead of just memorizing these cycles for… For the… Dr. Deb Muth 59:30Right? Like, they, like. Anju 59:32They just make sense to me. Dr. Deb Muth 59:34Yeah. Anju 59:35And I think that’s so important to understand, that all of this has science behind it, and it’s there, and the research is there. Dr. Deb Muth 59:46It’s just us having to learn how to utilize it, and recognize that not every person is going to be straightforward, and what we do for one might not work for another. There’s… It’s not as easy as prescribing a prescription and letting the person walk out the door in 10 minutes. That’s not what this is about at all. Anju 01:00:05No, and at MedMaps as well, they have a call for abstracts, and so we’re always looking for research, experience, so if any of the clinicians out there have, you know, things they want to share. then send an abstract to Maps. What a great blonde. I think, one of my doctor friends is doing an abstract on research that was done on sensory qigong massage. Dr. Deb Muth 01:00:34Oh. Anju 01:00:34And it helped with speech, and the theory was that, we were all thinking of the sensory system in the brain, the sensory system. In the periphery being affected neurologically, and how to turn that back on. So, it was… it’s… Dr. Deb Muth 01:00:51That’s neat. Anju 01:00:51Again, with the research, and with the science behind it, and with, like, clinical trials, and all of that. Dr. Deb Muth 01:00:58That’s awesome, I love that.For parents that are just starting in this journey, what would you recommend be their first one or two steps? Anju 01:01:10Educate, educate, educate? How do you get educated? I do think that, TakaNow.org is a good place for, like, a biomedical approach, or this functional approach for autism. It’s the Autism Community in Action. MedMaps is doing a parent conference in March. Dr. Deb Muth 01:01:31Oh, awesome. They usually do that around, Memorial Day, right? Anju 01:01:36They’ll do it around Labor Day in September. Dr. Deb Muth01:01:40Labor Day in September, okay. Anju 01:01:42Yeah, and then mid-March. Dr. Deb Muth 01:01:44Okay. Anju 01:01:45Yeah. And they hadn’t done a parent conference before, but we had parents that wanted to come to the conferences, and it was just for clinicians before. Dr. Deb Muth 01:01:54Got it. Is it Autism One that does theirs around Memorial Day? Anju 01:01:59Oh yeah, they don’t exist anymore. Dr. Deb Muth 01:02:01Don’t, really. Anju 01:02:03conferences. There was. Dr. Deb Muth 01:02:06NAA, the National Autism Association. Anju 01:02:09They don’t do a lot of parent conferences in functional medicine either, so there’s a few left. Documenting Hope. That’s another really nice one. Oh, that’s great. Dr. Deb Muth 01:02:21So, what last words do you want to leave with our listeners? Anju 01:02:29You know, that’s… people always ask that at the end of these… I, I do feel that, Listen to your heart, you know, follow your intuition. Dr. Deb Muth 01:02:40I’ll let that guide you. Anju 01:02:42There’s a lot of information, sometimes it gets to be too much information. It’s hard to process everything, try not to make impulsive decisions about things. And… If you have a child with special needs, or if you have a grandchild with, issues. Presume competence. There’s a lot there. Dr. Deb Muth 01:03:04Yeah. Anju 01:03:05Especially some of these kids with behavior issues. I don’t know how many patients of mine are… Put on psychotropic meds. Metabolic issues, and, you know… It’s like, a lot of them have pain, like headache, abdominal pain, and inflammation, and they’re treating them with psych meds. Dr. Deb Muth 01:03:25Yeah. That’s sad, isn’t it? Anju 01:03:28I think, you know, try to look for the underlying cause. Not just band-aid things. Dr. Deb Muth 01:03:34Where can listeners, learn more about your work and what you do? Anju 01:03:40Oh, that’s tough. I don’t have a book. One of these days. Dr. Deb Muth 01:03:48Yes! Anju 01:03:49Yes, one of these days. I think, you know, med maps, we have a… if they’re clinicians. Dr. Deb Muth 01:03:55Hmm? Anju 01:03:56I have lectured a lot. For, for, communities like Taka, so there’s just a lot of… lectures that I’ve given online. Dr. Deb Muth 01:04:09Awesome. Well, thank you for taking your time with us today. It’s been a great conversation with you. Anju 01:04:15Thank you so much for inviting me, Debra. I’m honored to be here, and thank you for doing the work that you do to put Put this out there for people, because it’s really important information. Dr. Deb Muth 01:04:27Thank you. Thank you for joining me today on Let’s Talk Wellness Now. Today’s discussion with Dr. Usman reminds us that there’s always more we can do. We can look deeper into biology, environment, and lifestyle. to heal the next generation. If this episode inspired you, please share it with a parent or a practitioner who believes every child deserves a chance to thrive. And to learn more about Dr. Usman, you can visit TrueHealthMedical.com or TrueHealingnaturals.com. And if you’re ready to explore your own root cause healing, visit us at Serenityhealthcarecenter.com. You can also follow me on Instagram, and don’t forget to subscribe so you never miss an episode of Let’s Talk Wellness now. Until next time. I’m Dr. Deb, reminding you to nurture your body, mind, and spirit. Be well, and I’ll see you soon.The post Episode 262 – The Root Cause of ADHD & Autism: Beyond the Diagnosis with Dr. Anju Usman Singh first appeared on Let's Talk Wellness Now.
Welcome to the third episode of our three-part series on colorectal cancer! In this episode of the Oncology Brothers we are joined by Dr. Rona Yaeger, a medical oncologist from the Memorial Sloan Kettering Cancer Center. Together, we dived into the management of common side effects associated with systemic treatments for colorectal cancer. Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Apple Podcast: https://podcasts.apple.com/us/podcast/oncology-brothers-practice-changing-cancer-discussions/id1653340966 Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Episode Highlights: • Overview of 5-FU and capecitabine, including the importance of DPYD mutation testing and side effects like cytopenia, mucositis, and cardiac toxicity. • Discussion on the use of 5-FU bolus in both metastatic and adjuvant settings. • Insights into managing oxaliplatin-induced neuropathy and the potential benefits of oral cryotherapy. • Clinical pearls for irinotecan, including the management of diarrhea and cholinergic effects. • Considerations for using Bevacizumab, including risks of hypertension, proteinuria, and blood clots. • Tips for managing side effects of anti-EGFR agents like Cetuximab and Panitumumab, including rash and infusion reactions. • An overview of oral agents such as encorafenib, TAS-102, and Regorafenib, with a focus on dosing strategies and side effect management. Join us as we explore these critical topics and provide valuable insights for healthcare professionals managing colorectal cancer treatments. Don't forget to subscribe for more episodes! #ColorectalCancer, #SideEffectManagement, #DPYDtesting, #ChemotherapyToxicity, #SupportiveCare
A pivotal JAMA randomized trial introduces an epigenetic twist to frontline therapy in high-risk DLBCL. Adding tucidinostat (HDAC inhibitor) to R-CHOP improved event-free survival (HR 0.72, P=0.02) and increased complete response rates (73% vs 62%) in MYC/BCL2 double-expressor lymphoma. Toxicity was higher but manageable. A quiet but meaningful shift—targeting biology, not just burden. #DLBCL #Lymphoma #Oncology #PrecisionMedicine #JAMA #ClinicalTrials
Today's Scripture is: Proverbs 27:6 **Today's devotional is in response to listener requests.** When a relationship feels powerful, fast, and deeply affirming, it can be hard to slow down and discern what's real. This episode unpacks the difference between emotional intensity and genuine love—helping you recognize red flags, trust your intuition, and move toward steady, grounded connection. In this episode: *Why intensity ≠ intimacy *The psychology behind fast attachment and emotional acceleration *Subtle signs of love bombing and relational urgency *How to evaluate consistency over chemistry *What it means to build safe, sustainable connection Go Deeper: Episode 178: How to Recognize Toxic Tactics, and Stop Taking the Bait Episode 24: Boundaries, the Spectrum of Toxicity, and a Note About Evil Connect with Dr. Alison on Instagram: @dralisoncook Join 80,000+ Soul Menders in Dr. Alison's free email community for ongoing reflection and support. While Dr. Cook is a counselor, the content of this podcast and any of the products provided by Dr. Cook are not specific counseling advice nor are they a substitute for individual counseling. The content and products provided on this podcast are for informational purposes only. Learn more about your ad choices. Visit megaphone.fm/adchoices
DL and Evil Jimmy go deep on the best and worst albums of 2001 — a year that somehow produced Gorillaz's self-titled debut, The Strokes' Is This It, System of a Down's Toxicity, Tool's Lateralus, Jay-Z's The Blueprint, and Jimmy Eat World's Bleed American all at once.They build a collective top 10, trading picks and hot takes: Gorillaz at number one, Toxicity at two, Is This It at three — plus arguments for Opeth's Blackwater Park, Converge's Jane Doe, Tool's Lateralus, Muse's Origin of Symmetry, Jay-Z's The Blueprint, White Stripes' White Blood Cells, and Neurosis rounding out the list.Along the way: why Nickelback and Creed represent everything wrong with 2001 mainstream rock, the case for Built to Spill's Ancient Melodies of the Future, Wilco's Yankee Hotel Foxtrot, the Toadies' Hell Below Stars Above, Ben Folds' Rockin' the Suburbs, Tenacious D's self-titled, and Tupac's Until the End of Time. Plus favorite songs of the year, a Stone Temple Pilots deep cut, Andrew W.K.'s She Is Beautiful, and a Clint Eastwood / Morgan Freeman life philosophy detour courtesy of the Gorillaz track.Part of Verse Chorus Verse's year-by-year and album-by-album music coverage.2001 music,Gorillaz,The Strokes,System of a Down,Tool,Jay-Z Blueprint,Jimmy Eat World,album rankings,year in music,indie rock,metal,music podcast
Featuring an interview with Dr Seth Wander, including the following topics: Deciding between liquid and tissue biopsy; role of epigenetics in oncogenic events (0:00) Potential role of thymidine kinase testing in monitoring response to therapy (4:56) Interpretation of next-generation sequencing testing; use of targeted therapy (10:59) Phase III lidERA Breast Cancer trial and its implications for the use of giredestrant (14:19) Interpreting plots from the Guardant360® test; future applications of circulating tumor DNA (19:07) Toxicity surrounding use of agents targeting the PAM signaling pathway; treatment for patients with PAM pathway alterations and ESR1 mutations (25:15) Potential role of artificial intelligence in profiling biomarkers; comparative efficacy of first- and later-line use of CDK inhibitors (30:26) Case: A woman in her mid 60s diagnosed with hormone receptor (HR)-positive, HER2-low metastatic breast cancer experiences disease progression after 5 years despite letrozole/ribociclib and is found to have ESR1 mutations, treated sequentially with elacestrant then trastuzumab deruxtecan (39:10) Case: A woman in her mid 50s who previously received treatment for localized disease develops progressive metastatic HR-positive, HER2-negative, PIK3CA-mutated breast cancer (45:31) Case: A woman in her late 70s with HR-positive, HER2-negative breast cancer who previously received treatment for localized disease is now diagnosed with progressive PTEN-deficient metastatic disease (51:36) Case: A woman in her early 70s with HR-positive, HER2-low metastatic breast cancer and bone metastases initially receives letrozole in combination with abemaciclib, then abemaciclib monotherapy (53:59) CME information and select publications
Brenda Sowers has had an incredible and crazy health journey—survivor of brain cancer, two brain tumors, and spike protein-related health complications. Before her health took a turn for the worse in 2019, Brenda was an active, healthy, ultra-runner. Thanks to her discovery of Dr. Thomas Seyfried and others in the metabolic health space, she has been able to reclaim her health from the brink of disaster. In this episode, Dr. Brian and Brenda talk about… (00:00) Intro (03:13) Brenda's battle with brain cancer (08:27) Brenda's experience of going through radiation and chemo therapy at the same time (09:53) How Brenda's discovery of the work of Dr. Thomas Seyfried led her down the metabolic health rabbit hole (14:00) Brenda's 2nd brain tumor and how she learned that she was suffering from Covid vaccine side effects (23:34) How spike proliferation in the body effects human health (27:54) How Brenda has been detoxifying her body of spike proteins (40:42) Running versus walking and rucking (42:57) Brenda's dietary journey trying carnivore and low carb (49:11) Thiamin, fiber, and keeping an open mind (54:48) Olive leaf (58:11) Switching from vegetarianism to carnivore (01:04:10) Outro For more information, please see the links below. Thank you for listening! Links: Brenda Sowers: IG: https://www.instagram.com/bsowers80/ Brain Tumor Companions: https://www.braintumorcompanion.com Dr. Brian Lenzkes: Arizona Metabolic Health: https://arizonametabolichealth.com/ Low Carb MD Podcast: https://www.lowcarbmd.com/ HLTH Code: HLTH Code Promo Code: METHEALTH • • HLTH Code Website: https://gethlth.com
In this episode of *PICU Doc on Call*, Drs. Monica Gray, Pradip Kamat, and Rahul Damania chat about a 17-year-old girl who ended up with acute liver failure after she intentionally took 22.5 grams of acetaminophen. She came in 48 hours later with really high transaminases and an INR of 5.5, so she was admitted to the PICU. The hosts break down how acetaminophen affects the body, walk through its four clinical stages, and discuss how to manage it—focusing on N-acetylcysteine as the primary antidote. They also touch on other treatments, like fomepizole. Thankfully, this patient recovered without needing a liver transplant, which really shows how important it is to have a team approach with intensivists, hepatologists, toxicologists, and psychiatry all working together.Show Highlights:Clinical case presentation of a 17-year-old girl with acetaminophen ingestion leading to acute liver failureMechanism of acetaminophen toxicity and its metabolic pathwaysEpidemiology of acetaminophen toxicity in pediatric populationsPathophysiology of acetaminophen overdose and its effects on liver functionClinical manifestations and progression of acetaminophen toxicity through various stagesEvaluation and diagnostic criteria for assessing acetaminophen toxicityManagement strategies for acetaminophen overdose, including the use of N-acetylcysteine (NAC).Discussion of adjunctive therapies such as fomepizole in severe cases.Importance of supportive care in managing complications of acute liver failureAn interdisciplinary approach to treatment involving various medical specialtiesReferences:Fuhrman & Zimmerman - Textbook of Pediatric Critical Care Chapter ***.Reference 1: 2019 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 37th Annual Report. Gummin DD, Mowry JB, Beuhler MC, Spyker DA, Brooks DE, Dibert KW, Rivers LJ, Pham NPT, Ryan ML. Clin Toxicol (Phila). 2020;58(12):1360.Reference 2: Pepin L, Matsler N, Fontes A, Heard K, Flaherty BF, Monte AA. Fomepizole Therapy for Acetaminophen-Induced Liver Failure in an Infant. Pediatrics. 2023 Oct 1;152(4):e2022061033. doi:10.1542/peds. 2022-061033. PMID: 37681263.Reference 3. Chiew AL, Buckley NA. Acetaminophen Poisoning. Crit Care Clin. 2021 Jul;37(3):543-561.Reference 4. Squires JE, Alonso EM, Ibrahim SH, Kasper V, Kehar M, Martinez M, Squires RH. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on the Diagnosis and Management of Pediatric Acute Liver Failure. J Pediatr Gastroenterol Nutr. 2022 Jan 1;74(1):138-158. doi: 10.1097/MPG.0000000000003268. PMID: 34347674.
We discuss this ominous complication of providing local anesthesia. Hosts: Elaine Jonas, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/LAST.mp3 Download Leave a Comment Tags: Critical Care, Toxicology Show Notes I. Pathophysiology & Mechanisms Definition: Systemic toxicity secondary to local anesthetic (LA) via accidental intravascular injection or excessive systemic absorption. Threshold: Occurs when plasma concentration exceeds the safety threshold for cardiac and neural tissue. Agent Profile: Bupivacaine (High Risk) Highly lipophilic with high protein binding. “Fast-on, Slow-off” Kinetics: Strong Na+ channel binding with extremely slow dissociation during diastole. Myocardial Depression: Direct inhibition of Ca2+ release from the sarcoplasmic reticulum, impairing contractility. Low CC:CNS Ratio: The dose required for cardiac collapse is very close to the dose that triggers seizures (narrow safety margin). Contributing Factors: Acidosis/Hypercapnia: Increases the fraction of free drug and promotes ion trapping in the brain/heart; shifts the LA-binding curve toward higher toxicity. Hypoxemia: Exacerbates myocardial depression and lowers seizure threshold. II. Risk Assessment & Prevention Patient-Specific Risk Factors Extremes of Age: Neonates (low α-1-acid glycoprotein) and elderly (reduced clearance). Body Composition: Low muscle mass/frailty (decreased volume of distribution). Organ Dysfunction: Hepatic: Reduced metabolism of amide LAs. Renal: Accumulation of metabolites; risk of metabolic acidosis lowering seizure threshold. Cardiac: Reduced cardiac output slows hepatic delivery/clearance; heart failure patients are more sensitive to Na+ channel blockade. Pregnancy: Increased sensitivity to cardiotoxicity. Procedural Risk Factors Vascularity of Site (Highest to Lowest Risk): Intercostal blocks (highest absorption rate). Caudal/Epidural. Interfascial plane blocks (e.g., TAP block). Psoas compartment/Sciatic. Brachial plexus. Technique: Large volume infiltration, lack of ultrasound, lack of incremental injection. Prevention Mandates Weight-Based Dosing: Lidocaine (Plain): Max 4.5 mg/kg. Lidocaine (with Epi): Max 7 mg/kg. Bupivacaine: Max 2.5–3 mg/kg. Incremental Injection: 3–5 mL aliquots with frequent aspiration. Intravascular Marker: Use Epinephrine (1:200,000) to detect accidental IV placement (HR increase >10 bpmor SBP increase >15 mmHg). III. Clinical Presentation Neurologic Phase (Early to Late) Subjective: Metallic taste, tinnitus, circumoral numbness/tingling. Objective: Visual disturbances, agitation, confusion, tremors. Critical: Generalized tonic-clonic seizures, rapid progression to CNS depression, coma, and apnea. Note: Early phases are often masked in patients receiving midazolam or propofol. Cardiovascular Phase Initial: Hypertension and tachycardia (if epi used) or transient stimulatory phase. Conduction Defects: PR prolongation, QRS widening (classic sign), bundle branch blocks. Dysrhythmias: Bradycardia (most common), VT/VF, PEA, asystole. Contractility: Profound, refractory hypotension and cardiogenic shock. IV. Immediate Management Algorithm Goal: Prevent hypoxia/acidosis and sequester the toxin. 1. Initial Actions Stop Injection: Immediately halt all LA administration. Call for Help: Specify “LAST Protocol” and “Intralipid Kit.” Airway Management: 100% O2. Hyperventilate slightly if needed to counter respiratory acidosis. Low threshold for intubation (hypoxia/acidosis rapidly worsen LAST). 2. Seizure Control First-line: Benzodiazepines (e.g., Midazolam). Avoid: Propofol if hemodynamically unstable (exacerbates cardiac depression). Neuromuscular Blockers: May be needed for ventilation, but remember they do not stop CNS seizure activity. 3. Lipid Emulsion Therapy 20% Indications: Start at first sign of serious toxicity (airway compromise, seizures, or CV instability). Bolus: 1.5 mL/kg IV over 1 minute. Infusion: 0.25 mL/kg/min immediately following bolus. If Instability Persists: Repeat bolus (up to 2 times). Increase infusion to 0.5 mL/kg/min. Upper Limit: ≈12 mL/kg total dose. 4. Modified ACLS Epinephrine: Use low doses (
00:00 Introduction and Season Overview 01:18 Coach Mox's Tenure and Team Performance 05:59 Breaking News: Coach Mox's Departure 12:11 Toxicity and Coaching Dynamics 17:59 Transfer Portal and Player Loyalty 26:28 Future of the Program and Potential Coaching Changes Follow The Ball Hawk Show: Bleav Network, Apple Podcasts, Spotify, and other podcasts platforms Ahmad Hawkins Website: http://www.ahmadhawkins.com Follow on X: @IAmBallHawk Instagram: iamballhawk Facebook: Ahmad Hawkins Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
On this, our 320th Evolutionary Lens livestream, we discuss whether it can happen here, or again. It is genocide. Growing up in a secular Jewish household in the 1970s and ‘80s, Bret remembers many discussions of whether it could happen again, and where, but it seems to be assumed that the repeated targets of atrocities cannot themselves ever engage in atrocity. Is this true? We discuss lineage selection, the nature of history and memory, diaspora, Israel. Also, the belligerence of the U.S. again Iran. Then: Washington state is allowing non-citizens to become peace and corrections officers, but if any in those positions make mean gestures or social media posts, they can be fired. Toxicity of both stripes—masculine and feminine—are in command in our political landscape, and we seem to have no good options.*****Our sponsors:ARMRA Colostrum is an ancient bioactive whole food that can strengthen your immune system. Go to http://www.armra.com/DARKHORSE to get 30% off your first order.CrowdHealth: Pay for healthcare with crowdfunding instead of insurance. It's way better. Use code DarkHorse at http://JoinCrowdHealth.com to get 1st 3 months for $99/month.Helix: Excellent, sleep-enhancing, American-made mattresses. Go to http://www.HelixSleep.com/DarkHorse to get 20% off sitewide.*****Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com/Heather's newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.comOur book, A Hunter-Gatherer's Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.orgThumbnail: Pool/Getty Images News*****Mentioned in this episode:Sinclair Lewis, It Can't Happen Here: https://www.alibris.com/It-Cant-Happen-Here-Sinclair-Lewis/book/3376310?qsort=p&matches=117Let that sink in: https://x.com/LibyaLiberty/status/2039695385464017281Trump on Iran: https://www.youtube.com/watch?v=6LJMfd0gYc8&t=992sWA state bill 5068: https://lawfilesext.leg.wa.gov/biennium/2025-26/Pdf/Bills/Session%20Laws/Senate/5068.SL.pdf?q=20260404090142Support the show
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