Research To Practice | Oncology Videos

Follow Research To Practice | Oncology Videos
Share on
Copy link to clipboard

Featuring the video recorded proceedings of events held in conjunction with important scientific symposia, live webcasts and closed meetings featuring the perspectives of renowned clinical investigators, these videos provide an overview of important advances in the management of a number of solid tu…

Dr Neil Love


    • Dec 5, 2024 LATEST EPISODE
    • weekdays NEW EPISODES
    • 1h 2m AVG DURATION
    • 1,396 EPISODES


    More podcasts from Dr Neil Love

    Search for episodes from Research To Practice | Oncology Videos with a specific topic:

    Latest episodes from Research To Practice | Oncology Videos

    Breast Cancer | Exploring the Current Management Paradigm for Patients with Metastatic Triple-Negative Breast Cancer

    Play Episode Listen Later Dec 5, 2024 59:42


    Featuring perspectives from Dr Priyanka Sharma and Dr Sara M Tolaney, including the following topics: Introduction: Metastatic Triple-Negative Breast Cancer (mTNBC) — The Patient Perspective (0:00) Selection and Sequencing of Antibody-Drug Conjugates (5:09) Dosing and Tolerability of Sacituzumab Govitecan; Use of Anthracyclines (14:39) Case: A woman in her early 60s with relapsed TNBC (HER2 2+) who experiences disease progression on T-DXd (Grade 2 interstitial lung disease) and receives sacituzumab govitecan — Shaachi Gupta, MD, MPH (22:04) Discussing Palliative and End-of-Life Care (32:40) PARP Inhibitors for TNBC with Somatic versus Germline Mutations; Cytopenias with PARP Inhibitors (37:53) The “Art of Oncology” — Building Trust with Patients and Family Members (45:05) Case: A woman in her mid 60s with recurrent TNBC with extensive chest wall involvement — Dr Gupta (48:44) Case: A man in his mid 40s with multiregimen-refractory AR-positive TNBC with an ERBB2 exon 20 insertion mutation — Dr Gupta (52:53) CME information and select publications

    Paroxysmal Nocturnal Hemoglobinuria | Practical Perspectives: Investigators Discuss the Current Management of Paroxysmal Nocturnal Hemoglobinuria

    Play Episode Listen Later Dec 4, 2024 106:18


    Featuring perspectives from Dr Gloria Gerber, Dr Jamie Koprivnikar, Prof Alexander Röth and Dr Jamile M Shammo, including the following topics: Introduction: Paroxysmal Nocturnal Hemoglobinuria (PNH) and the General Medical Oncologist Diagnosis of and myths and misperceptions about PNH (0:00) Overview — Biology and Pathophysiology Role of complement activation in PNH; classification and clinical presentation (7:00) PNH treatments and their complement targets (21:37) Current Management Approaches Mechanistic similarities and differences between crovalimab and other available C5 inhibitors; potential practical advantages of crovalimab (24:56) Timing for initiation of treatment for PNH (32:08) Management of clinically significant extravascular hemolysis and residual anemia in patients with PNH receiving C5 inhibitor therapy (43:08) Risk of evolution to aplastic anemia or myeloid malignancy (45:54) Clinical trial database establishing the efficacy and safety of the C5 complement inhibitors eculizumab and ravulizumab for PNH (48:47) Activity and safety of and clinical experience with crovalimab (53:03) Monitoring and management of PNH in pregnant patients (58:37) Case Presentations Case: A woman in her early 30s who receives a new diagnosis of classical PNH with symptomatic anemia — Dr Gerber (1:03:44) Case: A man in his early 30s with PNH initially treated with eculizumab who is transitioned to ravulizumab — Dr Koprivnikar (1:17:32) Case: A woman in her early 50s with a remote history of aplastic anemia — Dr Gerber (1:32:24) Case: A woman in her late 20s with PNH receiving active C5 inhibitor therapy who wishes to discuss alternative treatment options — Dr Koprivnikar (1:38:00) CME information and select publications

    Paroxysmal Nocturnal Hemoglobinuria | Jamile M Shammo, MD

    Play Episode Listen Later Dec 4, 2024 32:00


    Practical Perspectives: Investigators Discuss the Current Management of Paroxysmal Nocturnal Hemoglobinuria — Jamile M Shammo, MD CME information and select publications

    ER-Positive Metastatic Breast Cancer | 5-Minute Journal Club Issue 1 with Dr Seth Wander: Reviewing the Role of Oral SERDs in the Management of ER-Positive Metastatic Breast Cancer

    Play Episode Listen Later Nov 26, 2024 10:56


    Featuring an interview with Dr Seth Wander, including the following topics: ASCO Guidelines Rapid Recommendations Update for Testing for ESR1 Mutations (0:00) Real-world elacestrant use patterns and genomic biomarkers (4:43) Circulating tumor DNA (ctDNA) analyses with imlunestrant in the EMBER Phase I study (8:50) CME information and select publications

    Multiple Myeloma | Data + Perspectives: Clinical Investigators Explore the Application of Recent Datasets in Current Oncology Care

    Play Episode Listen Later Nov 26, 2024 52:46


    Featuring perspectives from Dr Sarah B Goldberg, Dr Brad S Kahl, Dr Sagar Lonial, Dr Joyce O'Shaughnessy, Dr Noopur Raje, Dr Joshua K Sabari, Dr Matthew R Smith, Dr Sonali M Smith, Dr Sandy Srinivas and Dr Seth Wander, including the following topics: Introduction (0:00) Current Therapeutic Approaches for Multiple Myeloma — Dr Lonial (0:37) Chimeric Antigen Receptor T-Cell Therapy, Bispecific Antibodies and Antibody-Drug Conjugates — Dr Raje (22:53) CME information and select publications

    Lung Cancer | The Implications of Recent Datasets for the Current and Future Management of Lung Cancer — A Review of Information from ESMO Congress 2024 and Other Conferences

    Play Episode Listen Later Nov 25, 2024 60:12


    Featuring perspectives from Dr Suresh S Ramalingam and Dr Gregory J Riely, including the following topics: Introduction: Tumor Treating Fields (0:00) Nontargeted Therapy for Lung Cancer — Dr Ramalingam (4:02) Targeted Therapy for Non-Small Cell Lung Cancer — Dr Riely (33:50) CME information and select publications

    Chronic Lymphocytic Leukemia | Meet The Professor: Optimizing the Management of Chronic Lymphocytic Leukemia — Part 2 of a 3-Part Series

    Play Episode Listen Later Nov 23, 2024 58:37


    Featuring perspectives from Dr Nicole Lamanna, including the following topics: Introduction (0:00) Case: A man in his late 60s with IGHV-mutated chronic lymphocytic leukemia (CLL) (trisomy 12) and progressive adenopathy — Bhavana (Tina) Bhatnagar, DO (1:22) Case: A woman in her mid 70s with IGHV-unmutated, del(13q) CLL and fatigue — Erik Rupard, MD (19:57) Case: A woman in her mid 80s with del(13q) CLL under watchful waiting develops progressive symptoms — Shams Bufalino, MD (30:00) Case: A woman in her early 60s diagnosed with small lymphocytic leukemia (SLL) now with disease progression on ibrutinib — Warren S Brenner, MD (33:08) Current role of pirtobrutinib; CAR T-cell therapy; Richter's transformation — Dr Brenner (36:04) Case: A man in his mid 40s with SLL who received second-line venetoclax/rituximab — Yanjun Ma, MD (50:01) CME information and select publications

    Tenosynovial Giant Cell Tumor | Oncology Today with Dr Neil Love: Optimizing the Management of Tenosynovial Giant Cell Tumor (Companion Faculty Lecture)

    Play Episode Listen Later Nov 21, 2024 25:25


    Featuring a slide presentation and related discussion from Dr Emanuela Palmerini, including the following topics: Background, diagnosis and disease course of tenosynovial giant cell tumor (TGCT) (0:00) Clinical data supporting systemic therapy for TGCT (10:19) Clinical data on emerging therapies for TGCT (17:28) Conclusion and future directions for TGCT (22:02) CME information and select publications

    Tenosynovial Giant Cell Tumor | Oncology Today with Dr Neil Love: Optimizing the Management of Tenosynovial Giant Cell Tumor

    Play Episode Listen Later Nov 21, 2024 63:41


    Featuring an interview with Dr Emanuela Palmerini, including the following topics: Pathology, clinical presentation, diagnosis and workup of tenosynovial giant cell tumor (TGCT) (0:00) Local therapies for and surgical management of TGCT (20:28) Available systemic therapies for TGCT (30:31) Investigational agents under development for TGCT (49:13) Patient case presentations (55:54) CME information and select publications

    Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia | Data + Perspectives: Clinical Investigators Explore the Application of Recent Datasets in Current Oncology Care

    Play Episode Listen Later Nov 20, 2024 56:12


    Featuring perspectives from Dr Sarah B Goldberg, Dr Brad S Kahl, Dr Sagar Lonial, Dr Joyce O'Shaughnessy, Dr Noopur Raje, Dr Joshua K Sabari, Dr Matthew R Smith, Dr Sonali M Smith, Dr Sandy Srinivas and Dr Seth Wander, including the following topics: Introduction (0:00) Updates in Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma — Dr Kahl (1:10) Updates in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma — Dr S Smith (33:32) CME information and select publications

    Prostate Cancer | Data + Perspectives: Clinical Investigators Explore the Application of Recent Datasets in Current Oncology Care

    Play Episode Listen Later Nov 20, 2024 57:11


    Featuring perspectives from Dr Sarah B Goldberg, Dr Brad S Kahl, Dr Sagar Lonial, Dr Joyce O'Shaughnessy, Dr Noopur Raje, Dr Joshua K Sabari, Dr Matthew R Smith, Dr Sonali M Smith, Dr Sandy Srinivas and Dr Seth Wander, including the following topics: Introduction (0:00) Role of Hormonal Therapy in Prostate Cancer Management — Dr M Smith (10:54) Other Available and Emerging Therapeutic Approaches — Dr Srinivas (37:03) CME information and select publications

    Hormone Receptor-Positive Metastatic Breast Cancer | Hope S Rugo, MD

    Play Episode Listen Later Nov 19, 2024 43:30


    Optimizing Therapy for Patients with Hormone Receptor-Positive Metastatic Breast Cancer Harboring PI3K/AKT/PTEN Pathway Abnormalities — Hope S Rugo, MD CME information and select publications

    Hormone Receptor-Positive Metastatic Breast Cancer | Optimizing Therapy for Patients with Hormone Receptor-Positive Metastatic Breast Cancer Harboring PI3K/AKT/PTEN Pathway Abnormalities

    Play Episode Listen Later Nov 19, 2024 56:49


    Featuring perspectives from Dr Komal Jhaveri and Dr Hope S Rugo, including the following topics: Introduction: PI3K/AKT/PTEN Pathway and Resistance to Endocrine Therapy (0:00) First-Line Therapy for HR-Positive Metastatic Breast Cancer (mBC) Harboring PI3K/AKT/PTEN Mutations (7:04) Treatment Options for Recurrent mBC with PI3K/AKT/PTEN Mutations (24:11) Beyond the Guidelines Survey (35:36) Faculty Case Presentations (51:27) CME information and select publications

    Lung Cancer | Data + Perspectives: Clinical Investigators Explore the Application of Recent Datasets in Current Oncology Care

    Play Episode Listen Later Nov 16, 2024 65:42


    Featuring perspectives from Dr Sarah B Goldberg, Dr Brad S Kahl, Dr Sagar Lonial, Dr Joyce O'Shaughnessy, Dr Noopur Raje, Dr Joshua K Sabari, Dr Matthew R Smith, Dr Sonali M Smith, Dr Sandy Srinivas and Dr Seth Wander, including the following topics: Introduction (0:00) Nontargeted Therapy for Lung Cancer — Dr Goldberg (9:07) Targeted Therapy for Non-Small Cell Lung Cancer — Dr Sabari (51:19) CME information and select publications

    HR-Positive Breast Cancer | Data + Perspectives: Clinical Investigators Explore the Application of Recent Datasets in Current Oncology Care

    Play Episode Listen Later Nov 16, 2024 63:53


    Featuring perspectives from Dr Sarah B Goldberg, Dr Brad S Kahl, Dr Sagar Lonial, Dr Joyce O'Shaughnessy, Dr Noopur Raje, Dr Joshua K Sabari, Dr Matthew R Smith, Dr Sonali M Smith, Dr Sandy Srinivas and Dr Seth Wander, including the following topics: Introduction (0:00) Hormone Receptor-Positive Breast Cancer — Dr O'Shaughnessy (10:45) Management of Relapsed/Refractory HR-Positive Metastatic Breast Cancer — Dr Wander (40:47) CME information and select publications

    Lymphoma | Gilles Salles, MD, PhD

    Play Episode Listen Later Nov 8, 2024 22:40


    What Clinicians Want to Know About the Current and Future Role of EZH1/2 Inhibitors in the Care of Patients with Lymphoma — Gilles Salles, MD, PhD CME information and select publications

    Lymphoma | What Clinicians Want to Know About the Current and Future Role of EZH1/2 Inhibitors in the Care of Patients with Lymphoma

    Play Episode Listen Later Nov 8, 2024 56:01


    Featuring an interview with Dr Gilles Salles, including the following topics: Epigenetic modifications and the role of EZH2 in the pathobiology of follicular lymphoma (FL) (0:00) Natural history of FL and current treatment landscape in the first-line setting (5:20) Testing approaches for the detection of EZH2 mutations (14:37) Mechanism of action of the EZH inhibitors tazemetostat and valemetostat (18:31) Tazemetostat monotherapy as treatment for relapsed/refractory FL (20:58) Ongoing evaluation of novel treatment approaches with tazemetostat for FL and other lymphomas (25:31) Approved indications for tazemetostat for wild-type FL and FL with EZH2 mutations; sequencing of tazemetostat with bispecific antibodies and CAR T-cell therapy (34:07) Available clinical data with the novel dual EZH1/EZH2 inhibitor valemetostat (42:37) Personal experience with CAR T-cell therapy and perspectives on possible underlying reasons for the development of T-cell lymphoma in patients receiving this treatment (44:35) Management of FL in patients who experience relapse within 24 months of receiving treatment (POD24) (48:25) Myths or misperceptions associated with tazemetostat and other therapies approved in the relapsed FL setting (52:15) Perspectives on the future treatment landscape of FL (54:29) CME information and select publications

    Lung Cancer | Oncology Today with Dr Neil Love: Special Edition — Key Presentations on Lung Cancer from Recent Major Conferences

    Play Episode Listen Later Nov 7, 2024 54:25


    Featuring an interview with Dr Stephen V Liu, including the following topics: Management of localized non-small cell lung cancer (NSCLC) (0:00) First-line treatment of advanced NSCLC (10:53) Targeted therapy for patients with NSCLC and actionable genomic alterations (30:24) Recent FDA approvals for NSCLC (37:49) Recent advances in small cell lung cancer (47:14) Lurbinectidin in combination with atezolizumab as front-line maintenance therapy for patients with early-stage SCLC (52:33) CME information and select publications

    Gastrointestinal Cancers | The Implications of Recent Datasets for the Current and Future Management of Gastrointestinal Cancers — An ESMO Congress 2024 Review

    Play Episode Listen Later Nov 6, 2024 62:25


    Featuring perspectives from Dr Tanios Bekaii-Saab and Dr Philip A Philip, including the following topics: Introduction (0:00) Colorectal Cancer, Anal Cancer and Pancreatic Cancer — Dr Philip (1:56) Gastroesophageal Cancers, Hepatocellular Cancer and Biliary Tract Cancers — Dr Bekaii-Saab (41:48) CME information and select publications

    Metastatic Breast Cancer | Improving Outcomes with First-Line Endocrine-Based Therapy for Patients with HR-Positive, HER2-Negative Metastatic Breast Cancer

    Play Episode Listen Later Nov 1, 2024 59:29


    Featuring perspectives from Prof Francois-Clement Bidard and Dr Kevin Kalinsky, including the following topics: Introduction: Confronting Metastatic Breast Cancer (mBC) (0:00) Mechanisms of Resistance to Endocrine Therapy in HR-Positive mBC; Use of Oral Selective Estrogen Receptor Degraders (SERDs) — Dr Kalinsky (13:18) Ongoing Evaluation of Early Therapeutic Switching for HR-Positive mBC Harboring ESR1 Mutations — Prof Bidard (35:52) CME information and select publications

    Mantle Cell Lymphoma | Michael Wang, MD

    Play Episode Listen Later Oct 30, 2024 53:11


    Practical Perspectives: Optimizing the Role of BTK Inhibitors in the Management of Mantle Cell Lymphoma | Faculty Presentation — Michael Wang, MD CME information and select publications.

    Mantle Cell Lymphoma | Practical Perspectives: Optimizing the Role of BTK Inhibitors in the Management of Mantle Cell Lymphoma

    Play Episode Listen Later Oct 30, 2024 57:58


    Featuring perspectives from Dr Tycel Phillips and Dr Michael Wang, including the following topics: Introduction: Interface Between Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma (0:00) Key Datasets — Overview and First-Line Therapy (7:16) Faculty Case Presentations — Dr Phillips (27:03) Key Datasets — Relapsed/Refractory Disease (35:40) Faculty Case Presentations — Dr Wang (48:06) CME information and select publications  

    HR-Positive Metastatic Breast Cancer | Oncology Today with Dr Neil Love: Potential Role of PROTAC ER Degraders in Therapy for HR-Positive Metastatic Breast Cancer (Companion Faculty Lecture)

    Play Episode Listen Later Oct 25, 2024 22:53


    Featuring a slide presentation and related discussion from Dr Erika Hamilton, including the following topics: Targeted therapies for ER-positive breast cancer (0:00) Clinical data with oral selective estrogen receptor degraders (2:13) Biological rationale for and mechanism of action of proteolysis-targeting chimeras (PROTACs) (7:07) Emerging data with PROTACs for ER-positive advanced breast cancer (9:17) Future directions with PROTACs for breast cancer (19:21) CME information and select publications

    HR-Positive Metastatic Breast Cancer | Oncology Today with Dr Neil Love: Potential Role of PROTAC ER Degraders in Therapy for HR-Positive Metastatic Breast Cancer

    Play Episode Listen Later Oct 25, 2024 45:32


    Featuring an interview with Dr Erika Hamilton, including the following topics: Pathophysiology and pharmacology of ER-positive breast cancer treatment (0:00) Clinical evidence available with oral selective estrogen receptor degraders (3:46) Mechanism of action of proteolysis-targeting chimeras (PROTACs) (13:22) PROTACs currently in clinical development (16:39) Case: A woman in her late 30s with HR-positive, HER2-negative metastatic breast cancer (mBC) experiencing progression on a CDK4/6 inhibitor (CDK4/6i) and an aromatase inhibitor (AI) (35:09) Case: A woman in her early 70s with HR-positive, HER2-negative mBC that progresses on a CDK4/6i and an AI (41:16) CME information and select publications

    Chronic Myeloid Leukemia | Jorge Cortes, MD

    Play Episode Listen Later Oct 24, 2024 27:12


    Practical Perspectives: Current Management of Chronic Myeloid Leukemia | Faculty Presentation — Jorge Cortes, MD  CME information and select publications

    Chronic Myeloid Leukemia | Practical Perspectives: Current Management of Chronic Myeloid Leukemia

    Play Episode Listen Later Oct 24, 2024 109:02


    Featuring perspectives from Dr Bhavana (Tina) Bhatnagar, Dr Amanda Blackmon, Dr Jorge Cortes, Dr Michael J Mauro and Dr Neil P Shah, including the following topics: Recently presented data affecting the treatment of newly diagnosed chronic myeloid leukemia (CML) (0:00) Case: A man in his mid 40s with newly diagnosed CML with tyrosine kinase inhibitor (TKI) tolerability issues but a good response (24:51) Case: A woman in her mid 80s with chronic-phase CML (CP-CML) with translocation (9;22) (40:26) Case: A woman in her mid 80s with CP-CML and notable comorbidities (43:12) Case: A woman in her early 50s with CP-CML intolerant to dasatinib (51:22) Case: A woman in her late 50s with CP-CML and TKI withdrawal syndrome (1:01:22) Case: A woman in her mid 50s with accelerated-phase CML (1:08:22) Case: A woman in her early 70s with CP-CML and a suboptimal response to second-line TKI (1:17:00) Case: A man in his mid 30s with CP-CML and a complex variant Ph-positive translocation (1:23:24) Case: A man in his mid 30s with CP-CML and a T315I mutation (1:28:55) CME information and select publications  

    Small Cell Lung Cancer | The Implications of Recent Datasets for the Current and Future Management of Small Cell Lung Cancer — A 2024 World Conference on Lung Cancer Review

    Play Episode Listen Later Oct 23, 2024 42:46


    Featuring perspectives from Dr Jacob Sands, including the following topics: Introduction: A man in his mid 60s with a lung nodule on lung cancer screening (0:00) Current and Future Management of Small Cell Lung Cancer (15:42) CME information and select publications

    Desmoid Tumors | Practical Perspectives: Optimizing Diagnosis and Treatment for Patients with Desmoid Tumors

    Play Episode Listen Later Oct 18, 2024 59:22


    Featuring perspectives from Dr Thierry Alcindor and Dr Mrinal Gounder, including the following topics: Introduction: Biology and Clinical Presentation (0:00) Case: A man in his mid 60s with desmoid fibromatosis — Dr Alcindor (12:36) Tyrosine Kinase Inhibitors (24:51) Gamma Secretase Inhibitors (31:02) Case: A woman in her early 40s with desmoid tumor treated with a gamma secretase inhibitor on a clinical trial — Dr Gounder (46:09) Case: A woman in her late 30s with a large groin desmoid tumor — Dr Gounder (51:52) Case: A woman in her early 30s with desmoid fibromatosis requiring treatment — Dr Alcindor (54:50) CME information and select publications

    Peripheral T-Cell Lymphoma | Oncology Today with Dr Neil Love: Peripheral T-Cell Lymphoma (Companion Faculty Lecture)

    Play Episode Listen Later Oct 17, 2024 25:18


    Featuring a slide presentation and related discussion from Dr Steven Horwitz, including the following topics: Front-line management of peripheral T-cell lymphomas (PCTLs) (0:00) Dose-intensified chemotherapy in combination with brentuximab vedotin for PTCL (9:59) Role of CD30 for PTCLs (14:36) Management of relapsed PTCL (20:40) CME information and select publications

    Peripheral T-Cell Lymphoma | Oncology Today with Dr Neil Love: Peripheral T-Cell Lymphoma

    Play Episode Listen Later Oct 17, 2024 46:17


    Featuring an interview with Dr Steven Horwitz, including the following topics: Overview of peripheral T-cell lymphomas (PTCLs) (0:00) Efficacy and safety of brentuximab vedotin in the management of treatment-naïve and relapsed PTCLs (9:57) Emerging therapeutic strategies for PTCLs (19:48) Case: A man in his early 50s with CD30-positive anaplastic large cell lymphoma who experienced complete response (CR) to BV-CHP and continued remission after consolidation with autologous stem cell transplant (ASCT) (25:53) Management of ALK-positive anaplastic large cell lymphoma (32:14) Case: A man in his late 50s with CD8-positive PTCL not otherwise specified who achieved CR with CHOEP and experienced relapse after ASCT (34:33) Case: A woman in her early 70s with chemorefractory CD30-positive angioimmunoblastic T-cell lymphoma (38:26) Ongoing first-line studies for T-cell lymphomas; association of CAR T-cell therapy with T-cell malignancies (42:18) CME information and select publications  

    Metastatic Non-Small Cell Lung Cancer | The Implications of Recent Datasets for the Current and Future Use of Nontargeted Therapy for Metastatic Non-Small Cell Lung Cancer

    Play Episode Listen Later Oct 16, 2024 60:08


    Featuring perspectives from Dr Edward B Garon and Dr Luis Paz-Ares, including the following topics: Introduction: Ivonescimab (0:00) First-Line Therapy for Metastatic Non-Small Cell Lung Cancer (NSCLC) without a Targetable Tumor Mutation — Dr Garon (11:47) Promising Therapeutic Strategies for Patients with Progressive Metastatic NSCLC — Dr Paz-Ares (42:01) CME information and select publications

    Chronic Lymphocytic Leukemia | Meet The Professor: Optimizing the Management of Chronic Lymphocytic Leukemia — Part 1 of a 3-Part Series

    Play Episode Listen Later Oct 10, 2024 58:59


    Featuring perspectives from Dr Matthew S Davids, including the following topics: Introduction: Is Chronic Lymphocytic Leukemia (CLL) the New Chronic Myeloid Leukemia? Cases We Didn't Hear About Last Week (0:00) Case: A man in his early 70s with IGHV-unmutated CLL (trisomy 12, del[17p]) receives ibrutinib for several years and is switched to acalabrutinib to lower the risk of cardiotoxicity — Warren S Brenner, MD (16:39) Case: A man in his mid 70s with relapsed atypical del(17p) CLL who previously received ibrutinib receives venetoclax/obinutuzumab — Bhavana (Tina) Bhatnagar, DO (22:10) Case: A woman in her early 80s with IGHV-mutated CLL begins treatment with zanubrutinib and 6 months later develops altered mental status due to cryptococcal meningitis — Erik Rupard, MD (33:00) Case: A woman in her early 80s with relapsed CLL (del[17p]/TP53 mutation) develops Stevens-Johnson syndrome while receiving ibrutinib — Spencer H Bachow, MD (38:21) Case: A man in his mid 90s with del(13q) CLL under observation for 12 years begins treatment with zanubrutinib and develops significant bruising/ecchymosis — Dr Rupard (41:14) Case: A woman in her late 70s with relapsed del(13q) CLL receives acalabrutinib and develops hyperleukocytosis — Dr Bhatnagar (45:44) Case: A woman in her mid 80s with rising white blood cell counts and asymptomatic recurrence of CLL (trisomy 12) receives rituximab with subsequent addition of venetoclax — Dr Brenner (50:20) Transformed CLL; CAR T-Cell Therapy (53:38) Journal Club with Dr Davids (54:26) CME information and select publications

    Diffuse Large B-Cell Lymphoma | Data + Perspectives: Clinical Investigators Discuss the Current and Future Management of Diffuse Large B-Cell Lymphoma

    Play Episode Listen Later Oct 9, 2024 60:32


    Featuring perspectives from Dr Christopher Flowers, Prof Grzegorz S Nowakowski and Dr Laurie H Sehn, moderated by Dr Flowers, including the following topics: Introduction (0:00) Front-Line Management of Diffuse Large B-Cell Lymphoma (DLBCL) — Dr Sehn (1:56) Case: A woman in her late 40s with epidural DLBCL and a compression fracture (Dr Flowers) (12:45) Case: A woman in her late teens with primary intestinal large B-cell lymphoma (Dr Nowakowski)(16:51) Integration of Novel Agents into the Care of Patients with Relapsed/Refractory DLBCL — Dr Flowers (21:14) Case: A man in his late 70s diagnosed with DLBCL with recurrent disease (Dr Nowakowski) (29:38) Case: A woman in her mid 70s with multiple comorbidities diagnosed with DLBCL (Dr Sehn) (36:17) Bispecific Antibody Therapy for DLBCL — Dr Nowakowski (39:39) Case: A man in his late 50s with no comorbidities with recurrent DLBCL (Dr Sehn) (50:50) Case: A patient in their mid 50s with DLBCL who experiences disease relapse after R-CHOP and CAR-T therapies (Dr Flowers) (54:34) CME information and select publications

    Non-Small Cell Lung Cancer with Actionable Targets Beyond EGFR | The Implications of Recent Datasets for the Current and Future Management of Non-Small Cell Lung Cancer with Actionable Targets Beyond EGFR

    Play Episode Listen Later Oct 8, 2024 58:14


    Featuring perspectives from Dr Ibiayi Dagogo-Jack and Dr Corey J Langer, including the following topics: Introduction: A Model for Targeted Treatment in Non-Small Cell Lung Cancer (NSCLC) (0:00) NSCLC with ALK, ROS1 and NTRK Rearrangements — Dr Langer (9:10) Current and Future Treatment of Metastatic NSCLC with RET, MET, HER2 and KRAS Alterations — Dr Dagogo-Jack (34:22) CME information and select publications

    Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia | Data + Perspectives: Clinical Investigators Discuss the Role of CAR T-Cell Therapy for Patients with Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia

    Play Episode Listen Later Oct 4, 2024 59:33


    Featuring perspectives from Dr Joshua Brody, Dr Matthew Lunning and Dr Jason Westin, moderated by Dr Lunning, including the following topics: Introduction (0:00) Integration of Chimeric Antigen Receptor (CAR) T-Cell Therapy into the Management of Diffuse Large B-Cell Lymphoma — Dr Westin (1:34) Current Role of CAR T-Cell Therapy for Other B-Cell Lymphomas — Dr Lunning (21:17) Tolerability and Other Practical Considerations with CAR T-Cell Therapy — Dr Brody (40:15) CME information and select publications

    Non-Small Cell Lung Cancer with EGFR Mutations | The Implications of Recent Datasets for the Current and Future Management of Non-Small Cell Lung Cancer with EGFR Mutations

    Play Episode Listen Later Oct 2, 2024 58:19


    Featuring perspectives from Dr Joshua K Sabari and Dr Helena Yu, including the following topics: Introduction: Checkpoint Inhibitors and Lung Cancer with an EGFR Mutation (0:00) Current Management of Metastatic Non-Small Cell Lung Cancer (NSCLC) with EGFR Mutations — Dr Sabari (5:39) Novel Therapeutic Approaches for NSCLC Harboring EGFR Mutations — Dr Yu (28:21) CME information and select publications

    Breast Cancer | Oncology Today with Dr Neil Love: Optimizing the Management of Metastatic BRCA-Negative, Triple-Negative Breast Cancer (Companion Faculty Lecture)

    Play Episode Listen Later Sep 25, 2024 27:22


    Featuring a slide presentation and related discussion from Dr Tiffany A Traina, including the following topics: Extended follow-up with pembrolizumab/chemotherapy for patients with previously untreated PD-L1-positive metastatic triple-negative breast cancer (mTNBC) (0:00) ASCENT trial: Survival advantage with sacituzumab govitecan versus physician's choice of chemotherapy for patients with relapsed/refractory TNBC (2:49) Treatment-associated side effects with sacituzumab govitecan (5:32) Activity of sacituzumab govitecan irrespective of TROP2 expression level and in patients with brain metastases (6:48) Ongoing Phase III studies evaluating sacituzumab govitecan in earlier lines of treatment (eg, ASCENT-03, ASCENT-04) (8:51) Efficacy and tolerability of trastuzumab deruxtecan in patients with HER2-low and HER2-ultralow metastatic breast cancer (10:26) Activity and ongoing investigations of other novel agents and strategies for mTNBC (20:05) CME information and select publications

    Breast Cancer | Oncology Today with Dr Neil Love: Optimizing the Management of Metastatic BRCA-Negative, Triple-Negative Breast Cancer

    Play Episode Listen Later Sep 25, 2024 49:41


    Featuring an interview with Dr Tiffany A Traina, including the following topics: Choice of chemotherapy to combine with first-line pembrolizumab for metastatic triple-negative breast cancer (mTNBC) (0:00) Ongoing investigations of androgen receptor-targeting agents for metastatic breast cancer (mBC) (8:37) Efficacy and CNS activity of sacituzumab govitecan for mTNBC; monitoring and management of treatment-associated side effects (14:34) Activity and tolerability of enfortumab vedotin for mTNBC (21:47) Rationale for combining antibody-drug conjugates with other systemic therapies for TNBC; early data and ongoing research efforts with combination approaches (24:13) Selection and sequencing of therapeutic options for advanced breast cancer (26:36) Clinical activity of trastuzumab deruxtecan; spectrum, severity and management of treatment-emergent toxicities (32:00) Case: A woman in her early 60s with mTNBC receives first-line pembrolizumab/carboplatin/gemcitabine (35:32) Case: A woman in her late 30s with TNBC and a short disease-free interval with adjuvant therapy is found to have CNS metastases that are treated with sacituzumab govitecan (40:40) Case: A woman in her late 60s and practicing physician is diagnosed with HR-negative, HER2-low mBC (44:16) CME information and select publications

    Biliary Tract Cancers | Striving for Consensus: Optimizing the Current and Future Management of Biliary Tract Cancers

    Play Episode Listen Later Sep 20, 2024 134:33


    Featuring slide presentations and related discussion from Dr Lipika Goyal, Dr James J Harding, Dr Milind Javle and Dr Robin K (Katie) Kelley, including the following topics: Current Role of Immunotherapeutic Strategies for Advanced Biliary Tract Cancers (BTCs) — Dr Kelley (0:00) Case: A man in his late 60s with advanced distal cholangiocarcinoma treated with the TOPAZ-1 regimen (13:27) Case: A woman in her early 70s with recurrent gallbladder cancer with biliary obstruction (15:56) Targeting FGFR and IDH Alterations for Advanced BTCs — Dr Goyal (35:00) Case: A woman in her late 30s with FGFR2 fusion-positive intrahepatic cholangiocarcinoma (ICC) (54:25) Case: A man in his late 60s with cholangiocarcinoma metastases to liver and bone (1:01:33) Case: A woman in her 60s with ICC with an IDH1 mutation (1:10:05) Emerging Role of HER2-Targeted Therapy for Advanced BTCs — Dr Harding (1:21:15) Case: A man in his early 40s with cholangiocarcinoma metastatic to the appendix (1:57:25) New Directions in the Management of BTCs — Dr Javle (2:01:09) CME information and select publications

    Neuroendocrine Tumors | Pamela Kunz, MD

    Play Episode Listen Later Sep 19, 2024 26:44


    Inside the Issue: Optimizing the Diagnosis and Treatment of Neuroendocrine Tumors | Faculty Presentation 2: Later-Line Treatment for Advanced NETs — Pamela Kunz, MD CME information and select publications

    Neuroendocrine Tumors | Simron Singh, MD, MPH

    Play Episode Listen Later Sep 19, 2024 22:44


    Inside the Issue: Optimizing the Diagnosis and Treatment of Neuroendocrine Tumors | Faculty Presentation 1: First-Line Therapy for Advanced Neuroendocrine Tumors (NETs) — Simron Singh, MD, MPH CME information and select publications

    Neuroendocrine Tumors | Inside the Issue: Optimizing the Diagnosis and Treatment of Neuroendocrine Tumors

    Play Episode Listen Later Sep 19, 2024 59:20


    Featuring perspectives from Dr Pamela Kunz and Dr Simron Singh, including the following topics: Introduction (0:00) Overview (4:04) Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors (NETs) (27:07) Multitarget Tyrosine Kinase Inhibitors for the Treatment of NETs (39:37) Other New Advances in the Management of NETs (50:29) CME information and select publications

    Claim Research To Practice | Oncology Videos

    In order to claim this podcast we'll send an email to with a verification link. Simply click the link and you will be able to edit tags, request a refresh, and other features to take control of your podcast page!

    Claim Cancel