Veteran healthcare analysts Max Jacobs and Nat Calloway riff on the latest news, talking about biotech as well as healthcare policy with a heavy dose of fact-based snark.
Maxim Jacobs, Nathaniel Calloway
In which our heroes discuss the impending doom coming from Wuhan. Also wtf FDA re SRPT?
In which we welcome our new commentator Wiktoria, and discuss the new BIIB shuck and jive.
Discuss the recent Relmada data, Geovax, Amyris, WeWork and more
People need some perspective on vaping and these opioid lawsuits
Novartis gives the FDA a headache, the FDA then gives Amarin a headache and people are trying to cure their problems with bleach
We discuss Auris Medical’s development programs for intranasal betahistine for acute vertigo as well as to treat some of the major side effects of antipsychotic medication.
We discuss Carmat's total artificial heart, the technology, approval pathways and commercial potential
Why would anyone sign up for a vomit boat trial or get thousands of electrodes implanted into their brains?
We cover Photocure’s marketed bladder cancer diagnostic product Hexvix/Cysview, its data and potential for growth in the United States and the prospects for future competition.
Why did selinexor get approved? What's going on with Roche/Spark? Why did ITCI have crazy results? Also a farewell.
Also ABBV buys a company, and why academia sucks.
Can anyone really beat diet and exercise for NASH? Also, buyer beware.
ASCO was a little uneventful and the Washington Post seems to be trying to make something out of nothing
Corbus: Targeting the Endocannabinoid System
Another what's wrong with people sort of episode
Also the trajectory of GILD and eyes full of bees.
On the Sisyphean struggle that is the amyloid hypothesis. Also, space herpes.
In which our heroes discuss Scott Gottlieb leaving, the new Theranos movie, and the risks of cutting sugar loaf.
In which our heroes discuss Roche's motivations with Spark. Also musings on senate subcommittees and goat wine.
Another NASH drug disappoints and three biotechs declare bankruptcy
GILD messes up in NASH while OMER cult members buy a bill of goods
Solid slips and Pain Therapeutics loses it. Also light bulbs for your ears and why Nat hates doctors.
What is wrong with people?
You can jump out of a plane without a parachute but don’t use tap water with your neti pot
What do Stemcentrx and MRNA have in common? Billions of other people's money.
We discuss our inevitable dystopian Gattaca future
If two drugs are better than one, six must be frickin' amazing. Also, Max and Nat figure out hot to improve NASH data and the tax system.
We discuss "the Lollapalooza of bad economic incentives" also known as the US healthcare system as well as the rest of the oligopolistic economy
How hard is it for companies to think things through?
A lot of good, bad and ugly things happened this week
Why do large pharma have a propensity to flush money down the toilet?
What's wrong with people? Especially OMER cult members and the managements of MNLO and TRVN.
This week diabetes patients win and Omeros shareholders lose.
A great week for hearts. Not so great week for TGTX shareholders.
Why does a scientist who forgets to file some paperwork lose his job when a pharma CEO that lies to investors get to keep his?
Gilead and Amgen had great data, Vital, not so much and we also talk about Phil Frost finally getting charged by the SEC
Think less but see it grow. Also, why you shouldn't be too hard on Mannkind and eat more cheese.
Is any amount of alcohol bad for you? Can magic mushrooms be good for you? What is hydrogen water?
Are low carb diets bad for you? Also, did CRISPR just bring us closer to Gattaca?
Should you trust a company that tells you to go home and bleach your skin and eyeballs? Max and Nat have the answer (its no).
Do you think this 40 year old GABA drug has a shot at a rare disease? A lesson in why you can't teach and old drug new tricks.
What do the healthcare system, the ivy league, and these pills have in common? Max and Nat have the answer.
Who can you trust when even the biggest biotechs massage the data? Max and Nat, that's who.
What's more likely to cure your brain: seaweed or a robot? We've got the answers.
Who's being fooled by these fake pipelines? Who's Pfizer fooling with its pricing? Max and Nat give you the answers
Max and Nat talk about their views of Amazon's recent entry into the pharmacy market as well as their thoughts on healthcare reform and the system in general.
Where Max and Nat try out this whole podcast thing to excellent results
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