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Leveling Up: Creating Everything From Nothing with Natalie Jill
If we are doing all the things in midlife and we still feel off. The brain fog. The bloating. The dull skin. The hormones that feel louder, not quieter. The recovery that takes three days from one glass of wine. This episode is for us. Because everyone keeps telling us the next step is hormones. HRT. Bioidenticals. Patches. Pellets. And those can absolutely help. But there are three quiet things slowing down in our bodies at the same time, and nobody is teaching us about them in plain English. The walls of our cells. Where hormones are supposed to knock and get a response. The body's trash truck. The thing that carries used hormones out of the body so they do not pile back up. The wallpaper lining our gut. The thing that keeps inflammation from running the whole show. All three slow down in midlife. That is why more hormones alone has not been the full answer for so many of us. My guest is Jessica Kane Berman, co-owner of BodyBio, a third-generation cellular health company her grandfather founded almost 30 years ago. Jessica walked through PCOS, fertility issues, mold, and Lyme, and she healed using the science her own family pioneered. We go through all three slowdowns in plain English, and we end with one thing we can do this week. This is the foundation underneath everything we are already doing. WE GO DEEP ON: • Why more hormones alone has not been the full answer in midlife • The three quiet things slowing down in our bodies at the same time • The walls of our cells, and why brain fog and dull skin are clues • The body's trash truck (bile), and why estrogen feels louder when it slows • The wallpaper lining our gut, and why food sensitivities and belly inflammation show up after 40 • Where HRT fits in (and why these three make HRT actually work) • What PC, TUDCA, and butyrate really do, in plain English • One simple thing to do this week if we are overwhelmed by where to start TIMESTAMPS • 00:00 | Why more hormones alone has not been the full answer • 06:00 | First slowdown. The walls of our cells. • 18:00 | Second slowdown. The body's trash truck. • 32:00 | Third slowdown. The wallpaper lining our gut. • 44:00 | All three together. Where HRT fits. • 52:00 | One thing to do this week. Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube
Immune Regulation, Omega-3 Nuance, and Himalayan Tartary Buckwheat with Dr. Austin Perlmutter, chief science officer of Big Bold Health. He details immune regulation as a nuanced, multidimensional system shaped by diet and lifestyle rather than simple “boosting.” Perlmutter explains Big Bold Health's focus on immunometabolism, educating about immune complexity, and conducting studies on nutraceuticals, including use of CGMs and clinical trials. He discusses why eating fish often outperforms refined fish-oil supplements, noting conventional processing (heat, bleaching, deodorizing, esterification) and loss of other lipids and nutrients. Perlmutter highlights specialized pro-resolving mediators (resolvins, protectins, maresins) and vitamins A and D as potentially better preserved in minimally processed oils, and reviews typical omega-3 intake and target ranges. The conversation also covers immunosenescence/inflammaging and Big Bold Health research on sprouted Himalayan Tartary Buckwheat, its high polyphenols (rutin, quercetin), microbiome effects, and studies including epigenetic aging clocks and brain outcomes.
Today on the radio show. 2 - Smoko. 6 - Rock 2000 Public holiday. 9 - My boyfriend Alan. 12 - Jacob Coin of Destiny update. 17 - Coin of Destiny. Build a new house or buy an old shitter? 22 - Fish Oil capsules. 26 - How fish oil is made. 28 - Origin Gee up. 33 - Worldy Dunc.. 35 - Giraffe chat. 38 - Python hunting. 42 - Benny Boy’s new Gaff. 45 - Late mail. 49 - Last drinks. Show Links. https://shorturl.at/PCqEz
Your fatigue, achy joints, and bad gut days might not be aging; they could be signs you're quietly inflamed. In this episode, I break down how to tell if chronic inflammation has set in, why it's driving some of the most serious diseases we face, and the simple, low-cost changes I use to cool it down: diet, sleep, stress, hydration, cold showers, red light, and a few key supplements. There's one daily habit that costs less than a dollar and one 30-second trick I promise you won't quit after seven days, but you'll have to listen to find out why. Hit play, and remember: it's just science. CLICK HERE TO BECOME GARYS VIP!: https://bit.ly/4ai0Xwg Thank you to our partners A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD AIRES: "ULTIMATE20 " FOR 20% OFF: https://bit.ly/4a3Duze BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp CYMBIOTIKA: "ULTIMATE10" FOR 10% OFF: https://bit.ly/4tjyluP GENETIC METHYLATION TEST (UK ONLY): https://bit.ly/48QJJrk GENETIC TEST (USA ONLY): https://bit.ly/3Yg1Uk9 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn SNOOZE: LET'S GET TO SLEEP!: https://bit.ly/4pt1T6V WHOOP: JOIN & GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW Watch the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8foX: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 - Intro of Show 00:18 - What inflammation actually is 00:52 - Signs you might be inflamed 01:30 - How cytokines drive chronic inflammation 02:10 - Anti-inflammatory diet basics 02:48 - Exercise and movement 03:08 - Managing chronic stress 03:24 - Quality sleep and your bedroom 04:12 - Hydration and mineral salt 04:42 - Cold exposure and cold showers 05:30 - Red light therapy and photobiomodulation 06:35 - Omega-3, turmeric, and curcumin 07:20 - Practical steps to start today 08:45 - Hydrogen water on the go 09:25 - Final habits and recap Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions. Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation. Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature. Learn more about your ad choices. Visit megaphone.fm/adchoices
For decades, fish oil has been the go-to source of omega-3, but a tiny Antarctic crustacean is now capturing the attention of scientists around the world. In this episode of The Living Terrain Journal, we explore the fascinating science behind krill oil and discover why its unique phospholipid structure, naturally occurring astaxanthin, and role in supporting healthy cell membranes have made it one of the most researched marine nutrients of recent years.Join us as we look beyond the headlines to examine how omega-3s contribute to normal heart function and normal brain function, why the structure of a nutrient may be just as important as the amount it contains, and how healthy cell membranes underpin communication throughout the body. From the remarkable ecosystem of Antarctica to the extraordinary complexity of the human body, this episode explores how modern science is helping us better understand the relationship between nutrition, cellular function and lifelong wellbeing.Whether you're already taking omega-3, curious about the differences between fish oil and krill oil, or simply fascinated by the way the body works, this episode offers an engaging, balanced and evidence-informed discussion that encourages us to think differently about health, not as isolated systems, but as a beautifully connected network of light, water, energy and biological communication.As always, the information shared in this podcast is provided for educational purposes and is not intended to diagnose, treat or prevent disease, or to replace personalised advice from an appropriately qualified healthcare professional. Food supplements should be used alongside a varied, balanced diet and a healthy lifestyle.
Omega-3 fatty acids remain one of the most researched and widely recommended nutrients for supporting overall health. On this episode, Jared welcomes Nicole Gitlin from Nordic Naturals to explore the science behind EPA and DHA, the differences between fish oil, cod liver oil, and krill oil, and how omega-3s support healthy brain function, cardiovascular wellness, inflammation balance, mood, and healthy aging. They discuss research-backed dosing strategies, why quality matters when choosing an omega-3 supplement, and how omega-3s may benefit children, adults, and even pets. Jared also shares why omega-3s remain a cornerstone of his Vital 5 protocol and why consistent use may be one of the most important nutritional investments you can make for long-term wellness. Plus, learn about Nordic Naturals' efforts to support cleaner oceans through their Coastal Cleanup initiative.Products:Vital 5 Omega-3 + AntioxidantsNordic Naturals Omega-3 ProductsVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/
Cardiovascular Protection Beyond Statins--Nattokinase, Vitamin K2 MK-7, and Clinical Cardio Six: Neil Levin of NOW Foods/Protocol for Life Balance details cardiovascular protection beyond cholesterol-lowering drugs, emphasizing nutrient sufficiency, therapeutic “nutraceutical” dosing, and physician partnership with testing. They discuss nattokinase from fermented natto (typical 2,000 fibrinolytic units/day), describing research on reduced fibrinogen, improved blood viscosity and microcirculation, blood-pressure normalization, and higher-dose data suggesting benefits for arterial thickness and lipids without excessive blood-thinning. They review vitamin K: K1 for normal coagulation (risk with Coumadin relates to day-to-day variability) and K2 for calcium metabolism, highlighting MK-7's longer half-life and potency versus MK-4 and recommending pairing K2 with vitamin D. Levin outlines PFLB Clinical Cardio Six (D3, L-carnitine, hawthorn leaf/flower, solubilized grape seed extract, CoQ10, MK-7), ingredient sourcing/testing, omega-3 benefits, red yeast rice context, and controversy around vitamin E meta-analyses.
Fish Oil Supplements And Alzheimer's-Related Decline A two-year randomized, double-blind, placebo-controlled trial led by researchers at USC tested whether 2,000 mg of DHA fish oil daily could slow Alzheimer's-related brain changes in 365 adults ages 55–80 who rarely consumed fish and had at least one Alzheimer's risk factor. Researchers confirmed the supplement reached the brain by measuring a roughly 17% increase in cerebrospinal fluid DHA after six months. Despite successfully increasing brain DHA levels, participants taking fish oil showed no significant improvements in memory, global cognitive function, or hippocampal volume compared to placebo after two years. Host Dave Asprey explains why raising a single biomarker doesn't always translate into better brain performance, why nutrition works differently inside a complete dietary pattern than as an isolated supplement, and what this study means for anyone relying on fish oil as an Alzheimer's prevention strategy. Sources: https://medicalxpress.com/news/2026-06-fish-oil-supplements-alzheimer-decline.pdf https://www.cnn.com/2026/06/18/health/omega-3-fish-oil-algae-supplement-wellness ~~ DASH Diet Showed the Strongest Link to Long-Term Brain Health Researchers from Harvard analyzed dietary data from 159,347 participants across three long-running U.S. health studies to examine how eating patterns influence cognitive aging. Participants completed dietary questionnaires every four years over several decades, allowing investigators to compare six healthy dietary patterns, including the DASH and Mediterranean diets. While all six were associated with better cognitive health later in life, adherence to the DASH diet produced the strongest association, with participants showing roughly a 40% lower risk of subjective cognitive decline and stronger performance on objective cognitive testing. The protective relationship was strongest when healthy eating habits began during midlife. Host Dave Asprey breaks down why blood sugar control, lower inflammation, and healthier blood vessels may be the real drivers behind long-term brain resilience, and why your dietary choices in your 40s and 50s may have an outsized impact on cognitive aging decades later. Sources: https://jamanetwork.com/journals/jamaneurology/article-abstract/2845466 https://www.health.harvard.edu/diet-and-nutrition/harvard-study-six-healthy-diets-linked-with-better-long-term-brain-health https://www.eurekalert.org/news-releases/1117225 ~~ Scientists Identified an Ancient Brain Circuit That Filters Distractions Johns Hopkins researchers discovered a small population of inhibitory neurons within an evolutionarily ancient brainstem region that appears to control selective attention by determining which sensory information deserves focus and which distractions should be ignored. Mice trained on visual attention tasks consistently ignored irrelevant stimuli until researchers temporarily silenced these neurons, causing even weak distractions to hijack their attention while leaving vision and movement otherwise unaffected. Similar brain circuits exist in birds, reptiles, and other vertebrates, suggesting this attentional filtering system evolved long before the modern human cortex. Host Dave Asprey explains why attention may depend on much older brain circuitry than previously believed, how this discovery could reshape our understanding of ADHD and autism, and why future therapies may target the brainstem instead of the prefrontal cortex. Sources: https://www.sciencedaily.com/releases/2026/06/260624025426.htm ~~ Nearly Half of Older Adults Improved With Age Instead of Declining A Yale-led study followed 11,340 adults age 65 and older for up to 12 years using repeated measurements of cognition and walking speed to better understand how aging changes over time. Rather than finding universal decline, researchers discovered that 45% of participants improved in either cognitive function, physical performance, or both. Nearly one-third experienced measurable cognitive improvements, while over one-quarter improved physically. Researchers also found that participants with more positive beliefs about aging were significantly more likely to improve, even after accounting for education, chronic illness, depression, and other health factors. Host Dave Asprey explores why expectations about aging may become biologically embedded, why decline is far less inevitable than conventional medicine often assumes, and how mindset may directly influence healthy longevity. Sources: https://www.sciencedaily.com/releases/2026/06/260620100428.htm ~~ Glyphosate May Be Contributing to Antibiotic-Resistant Superbugs Researchers publishing in Frontiers in Microbiology examined 102 bacterial strains collected from hospitals, agricultural land, and protected wetlands to investigate whether glyphosate exposure contributes to multidrug antibiotic resistance. Hospital bacteria demonstrated extensive resistance to both antibiotics and glyphosate, while even bacteria living inside protected nature reserves displayed measurable glyphosate resistance despite no direct herbicide application. Genetic analysis suggested resistant bacterial strains may move between agricultural environments and hospitals through shared waterways and sediments. The researchers argue pesticide safety testing should also evaluate whether chemicals encourage antibiotic resistance, one of the world's fastest-growing public health threats. Host Dave Asprey explains why environmental toxins may have unintended effects on the human microbiome, how herbicides could influence antimicrobial resistance beyond farming, and why environmental biology increasingly belongs in conversations about human health. Sources: https://www.sciencedaily.com/releases/2026/06/260620100434.htm https://www.openaccessgovernment.org/common-weedkiller-glyphosate-linked-to-rise-in-superbugs-scientists-warn/207515/ ~~ Butterflies That Barely Age Could Unlock New Longevity Pathways Researchers from the University of Bristol found that Heliconius butterflies live dramatically longer than closely related butterfly species while aging much more slowly. In one comparison, Heliconius hewitsoni survived up to 348 days, while a closely related species lived only 14 days. Unlike most butterflies, Heliconius feed on pollen throughout adulthood, providing amino acids that help preserve muscle function and physical performance with age. However, even when pollen was removed, these butterflies still significantly outlived their relatives, suggesting evolved genetic and metabolic mechanisms also contribute to their exceptional longevity. Host Dave Asprey explores why nature continues to provide unexpected models for slowing biological aging, what scientists hope to learn from species that naturally maintain function over time, and how comparative biology may uncover entirely new pathways for extending human healthspan. Sources: https://www.sciencedaily.com/releases/2026/06/260622014302.htm ~~ This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want mechanism-level insights into omega-3 supplementation and Alzheimer's prevention, nutrition strategies for preserving cognitive health, newly discovered brain circuits controlling attention, the surprising biology behind healthy aging, environmental drivers of antibiotic resistance, and what one remarkably long-lived butterfly can teach us about extending healthspan. Host Dave Asprey connects randomized clinical trials, large population studies, neuroscience discoveries, microbiology research, and evolutionary biology into practical frameworks for improving brain performance, resilience, and longevity. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: fish oil Alzheimer's study, DHA supplements memory, omega-3 brain health, DASH diet cognition, dementia prevention diet, cognitive decline nutrition, selective attention brainstem, focus neuroscience, ADHD brain research, positive aging beliefs, healthy aging study, cognitive improvement older adults, glyphosate antibiotic resistance, superbugs glyphosate, environmental toxins microbiome, butterfly longevity research, Heliconius aging, longevity science, biohacking news 2026, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today - Neuronic | Go to www.neuronic.online Code DAVE for $100 off - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:18 – Story #1 Fish Oil 02:31 – Story #2 DASH Diet 03:49 – Story #3 Brain Stem Attention Filter 05:59 – Story #4 Cognitive Decline Lies 08:24 – Story #5 Glyphosate 10:16 – Story #6 Butterfly Lifespan Research 12:16 – Biohacking Criticism Response See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Should you stop taking glucosamine based on a new study linking it to Alzheimer's? What's behind the spate of “Tai Chi Walking” social media posts? Undereye “festoons”—what to do about them? Are antibiotics the only treatment for SIBO? Vaping after smoking hikes risk for lung cancer.
More than just a game—Knicks overcoming odds in game 4 comeback is a parable of resilience; A one and done lifetime cholesterol fix via gene modification; Will cataract surgery interfere with benefits of light exposure? Do amounts of vitamin A in various supplements taken together court the risk of toxicity? Smartphones and social media create real harm for adolescents; Experts determine the exact right amount of sleep down to the minute—but is it overreach?
The “Enhanced Games”, with no-holds-barred performance-enhancing drugs, yields scant advantages over “clean” contests; Does saturated fat increase insulin resistance? Can a heart attack victim avoid statin use with CoQ10? Omega-3 fish oil shows promise vs. type 2 diabetes; Motorized e-scooter use needs to be regulated NOW!
There is a 45% chance the fish oil sitting in your cabinet right now is already oxidized. And rancid omega-3s do not just fail to help you. Research shows they generate pro-inflammatory byproducts that work against everything you are taking fish oil for. Dr. G breaks down exactly how this happens, how to test what is in your cabinet tonight with zero equipment, and what to actually look for before you buy another bottle. In this episode, you will learn: • The two oxidation markers most brands count on you never knowing about, the peroxide value and the anisidin value, and the total oxidation score that tells you whether your fish oil is actually fresh • Why the number on the front of your fish oil bottle is not the amount of omega-3s you are getting, and the simple math that reveals whether you have been underdosing for years • The at-home test you can do right now with one capsule, a pin, and 30 seconds that will tell you immediately whether to keep your fish oil or throw it away Plus the specific brands that passed Dr. G's independent investigation for certificate of analysis standards, packaging, storage, meaningful EPA and DHA doses, and proper oxidation scores. Timestamps: 0:00 - Intro 1:00 - The George Washington University Study That Exposed What's on Shelves 1:46 - Peroxide Value, Anisidine Value & the TOTOX Score Explained 2:18 - Why Fish Oil Is One of the Most Chemically Fragile Supplements You Can Buy 3:10 - What Legitimate Brands Do to Protect Their Oil (And What to Look For) 3:39 - The Label Scam: 1,000mg of Fish Oil Is Not 1,000mg of Omega-3s 4:24 - What a Clinically Meaningful Dose of EPA and DHA Actually Looks Like 5:09 - Three Questions to Ask Any Fish Oil Brand Before You Buy 7:00 - How to Test the Fish Oil in Your Cabinet Right Now 8:08 - The Brands That Passed Dr. G's Investigation Learn more about your ad choices. Visit megaphone.fm/adchoices
Can topical B12 help relieve itching?The types of doctors to avoidGetting back to basicsA case study of lavender oil helping to relieve itchingYou say you're dairy sensitive but you use whey protein. Please explain.What are your thoughts on a lactose relief patch that is on offer?
In this conversation, Dr. Sanda Moldovan and Udo Erasmus delve into the significance of essential fatty acids, particularly omega-3 and omega-6, in maintaining health. Udo shares his personal journey from a war-torn childhood to becoming a pioneer in health and nutrition, emphasizing the importance of understanding essential nutrients and the dangers of processed oils. The discussion highlights the need for a holistic approach to health, aligning with nature's design, and the power of whole foods and spices in promoting well-being. In this enlightening conversation, Dr. Sanda Moldovan and Udo Erasmus delve into the importance of food quality, the balance of essential fatty acids, and their impact on health. They discuss the significance of omega-3 and omega-6 fatty acids, the dangers of processed oils, and the necessity of proper oil storage. Udo emphasizes the need for a holistic approach to health, advocating for inner peace and the right dietary choices to enhance overall well-being. Want to see more of The Holistic Dentistry Show? Watch our episodes on YouTube! Do you have a mouth- or body-related question for Dr. Sanda? Send her a message on Instagram! Remember, you're not healthy until your mouth is healthy. So take care of it in the most natural way. Key Takeaways: (09:12)Understanding Essential Nutrients (12:10)The Role of Omega-6 Fatty Acids (15:11)The Dangers of Processed Oils (18:01)Health and Nature's Design (20:59) The Power of Whole Foods and Spices (23:58) Navigating Food Quality and Safety (25:48) The Essential Fatty Acids: Omega-3 and Omega-6 (28:01) The Impact of Omega-3 on Health (30:30) Inflammation and Essential Fatty Acids (32:16) Sources and Ratios of Omega Fatty Acids (34:40) The Importance of Oil Storage and Handling (36:15) The Dangers of Fish Oils (40:21) Three Non-Negotiable Rules for Essential Fatty Acids Connect with Udo Erasmus: Instagram: https://www.instagram.com/udoerasmus/ Website: https://udoerasmus.com/ Udo's Choice Brand: https://www.florahealth.com/collections/udos-choice Books & Products: https://udoerasmus.com/products/ Connect With Us: For dentists, hygienists and anyone interested wanting a deeper understanding of ozone in dentistry, this is an excellent place to start, my clinical introduction course is designed to give practitioners a practical, evidence-informed foundation built from more than 20 years of experience using ozone across every dental specialty. https://integrativedentalhealthinstitute.com/ AskDrSanda | YouTube BeverlyHillsDentalHealth.com | Instagram DrSandaMoldovan.com | Instagram Orasana.com | Instagram
Send us Fan MailHuman genetic variation in dietary fat metabolism and its implications for health & disease.TOPICS DISCUSSED:Linoleic Acid Rise: Linoleic acid now comprises 6-8% or more of energy in Western diets.Metabolic Pathways: Omega-6 linoleic acid converts to arachidonic acid and pro-inflammatory oxylipins; omega-3 ALA converts via shared enzymes to EPA/DHA with anti-inflammatory effects.FADS Genetic Variants: Ancestry-linked haplotypes in the FADS cluster create large “pipe” size differences, altering fatty acid by up to 40% between ancestral and derived versions.Population Differences: African ancestry populations often have high-conversion “big pipe” genotypes; Indigenous American ancestry populations have low-conversion “small pipe” genotypes; European ancestry comes with a mix of both.Omega-3 Deficiency: High linoleic intake suppresses EPA production, especially in small-pipe populations, contributing to hypertriglyceridemia and fatty liver in Mexican cohorts.Clinical Evidence: Reanalysis of VITAL trial showed 83% reduction in myocardial infarction with omega-3 supplementation in African Americans; Mexican data link low EPA to unique diabetes forms.Methodological Issues: Compositional data (from GC-FID measurements) versus absolute concentration measurements can flip relationships between linoleic acid and key biomarkers.ABOUT THE GUEST: Floyd Chilton PhD is Professor and Director of the Center for Precision Nutrition and Wellness at the University of Arizona. His research focuses on functional genomics, fatty acid metabolism, and precision nutrition, particularly how genetic ancestry influences responses to dietary fats.RELATED EPISODE:M&M 291: Omega Polyunsaturated Fats & Inflammation | Philip CalderSupport the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Allen Bookatz, and Dr. Jup Kuipers come together live in studio in Washington, D.C. to discuss the dangers of over-optimization and the "more is better" mentality. They explore real clinical case studies of patients who inadvertently damaged their health by blindly following supplement trends. Join us as we delve into: The dangers of over-supplementing with high-dose Fish Oil and Vitamin B6. How shifting to an "Omega-3 dominant" ratio can actually hinder your immune system's ability to heal injuries. Why you should treat metabolomic testing like the dashboard of a car to prevent the "check engine light" of chronic disease. How clinical metabolomics allows you to stop guessing and start subtracting unnecessary pills from your daily routine. This episode is for you if: You are experiencing wellness burnout and taking a massive handful of supplements every day without knowing if they are working. You want to understand the difference between being "fit" (e.g., running a marathon) and being truly cellularly "healthy." You are curious about functional testing and how it differs from the standard disease-focused bloodwork at a primary care clinic. You want a clear strategy to cut through social media influencer noise and build a foundational, personalized health protocol. You can also find this episode on… YouTube: https://youtu.be/WSNOBi1e7WY Find more from Health Optimization Medicine and Practice (HOMeHOPe):Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions:Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
For more information and support, join us at https://thecirsgroup.com Jacie and Barbara cover Phase Two (part two of five) of the Shoemaker Protocol for CIRS, focusing on foundational steps before starting binders: Lipid replacement therapy (primarily fish oil) to lower inflammation and help prevent common binder side effects like fatigue, constipation, and overall dryness, with Shoemaker-recommended omega-3 dosing (EPA 2,400 mg and DHA 1,800 mg daily) and cautions about blood-thinning; Limbic retraining to address errant threat signals from chronic illness, with nuance that intensive programs can be too difficult early on and may work better once out of exposure and/or on binders, while also warning against symptom suppression without addressing root causes; And the critical priority of getting out of exposure through testing (dust tests for mold, endotoxins, and actinos), remediation or moving, and exploring hidden, internal exposures that can cause plateaus or backslides in your health. Be sure to subscribe so you don't miss the next episode, all about Phase Three, removing the toxic burden! For more information and support, join us at https://thecirsgroup.com TIMESTAMPS 00:00 Phase Two of the Shoemaker Protocol 01:25 Why this foundational phase matters 02:54 What is Lipid Replacement? and why is it important? 06:17 Fish Oil / lipid dosing tips 08:04 Limbic Retraining explained 10:51 When Limbic Retraining backfires 14:23 Hyperreactivity Catch-22 18:25 Get out of exposure 20:42 Hidden exposures and healing stalls 22:27 Key takeaways and next phase 24:08 Wrap up and resources For more information and support, join us at https://thecirsgroup.com Check out these episodes mentioned in this episode: Interview with Michael Schrantz about remediation: https://youtu.be/_BEwFVdpRcY?si=mzNeGslwGjaYhWqi Interview with Bill Weber about testing your home: https://youtu.be/RlKjTqVAeNU?si=Eymfvcdk4G6kzylV Interview with Kendra Seymour on choosing a remediator or IEP: https://youtu.be/zmt9e42LLac?si=cTTvunobvEt8YL_n Dust testing 101: https://youtu.be/nRrZs7xbXcc?si=55oXFRCV5kO_p0JD Endotoxin episode: https://youtu.be/O0iKndNzfYA?si=X-iX1NoRO2U7U-QV Actinos episode part one: https://youtu.be/yf9EoTbyAEo?si=d2KUSzNpX2cs0DKE and Part two: https://youtu.be/2rCXhUP6dbY?si=wDHiSy58Vw5fZ5fa Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs The CIRS Group: Support Community: https://thecirsgroup.com Instagram: https://www.instagram.com/thecirsgroup/ Find Jacie for carnivore, lifestyle and limbic resources: Jacie's book on the Carnivore diet! https://a.co/d/8ZKCqz0 Instagram: https://www.instagram.com/ladycarnivory YouTube: https://www.youtube.com/@LadyCarnivory Blog: https://www.ladycarnivory.com/ Find Barbara for business/finance tips and coaching: Website: https://www.actlikebarbara.com/ Instagram: https://www.instagram.com/actlikebarbara/ YouTube: https://www.youtube.com/@actlikebarbara Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.
Dr. Bill Harris is a leading omega-3 researcher, founder of the Omega-3 Index, and co-founder of OmegaQuant, specializing in fatty acids, cardiovascular health, and nutrition science. Show partners: Troscriptions - 10% off your first order by using the code "JESSE" at checkout Ketone-IQ - Save 30% off your subscription order plus youʼll get a free gift with your second shipment by using this link LMNT - Claim your free LMNT Sample Pack with any purchase by using this link Show notes: jessechappus.com/705
For thirty years, the supplement aisle has sold fish oil as one of the simplest decisions you can make for your brain. In 2026, two research teams on opposite sides of the world published papers that complicate that story, and the literature behind them has been building for almost twenty years.IN THIS INVESTIGATIONWhat a 2026 ADNI cohort study of 800+ older adults actually foundWhy faster cognitive decline in fish oil users showed up on every measureWhat the brain imaging revealed when classic Alzheimer's pathology came back negativeThe 2026 Cell Reports mechanism work in repetitive brain injuryWhy EPA and DHA do different things inside the brain, and why most trials ignored the differenceTwenty years of cognitive trials nobody connected, including a 2006 trial whose biomarkers, re-analyzed in 2021, told a different storyWhat the 2026 authors themselves said about how to read their own findingsDose, baseline status, oil quality, and physiological context; the conditions the supplement aisle has never asked aboutWhat twenty years of brain literature actually supports if you take fish oil todaySubscribe for more investigations.
Broadcast from KSQD, Santa Cruz on 5-14-2026: An emailer from Switzerland follows up on the case of neurological symptoms, warning about the fox tapeworm Echinococcus multilocularis from unwashed garden vegetables and tick-borne encephalitis requiring the FSME vaccine available in Europe. Dr. Dawn adds that cysticercosis from undercooked pork leaves calcified brain lesions detectable on CT scans. Dr. Dawn covers the Andes hantavirus outbreak that sickened at least eleven people on a cruise ship, with the virus spreading person-to-person unlike other hantaviruses. She explains that Andes virus grows to unusually high levels in blood and resists antimicrobial compounds in human saliva, with super-spreaders driving transmission chains. British paratroopers had to parachute medical supplies to an infected passenger on remote Tristan da Cunha island. Dr. Dawn reviews brain health supplements with UCLA longevity expert Gary Small. Both recommend curcumin (500-1,000mg) for anti-inflammatory effects and CoQ10 for statin users. She endorses multivitamins and high-quality fish oil but considers creatine, phosphatidylserine, and nicotinamide riboside insufficiently proven for cognitive enhancement. A caller asks about supplements and testosterone for a 77-year-old. Dr. Dawn recommends topical testosterone (patches, creams, gels) over injections to avoid testicular shrinkage and elevated sex hormone-binding globulin. She emphasizes protein intake matching one's age in grams, branched-chain amino acids during exercise, and warns against fasted training after age 65. An emailer shares news that PCOS is being renamed to polyendocrine metabolic ovarian syndrome (PMOS) because many patients lack ovarian cysts, and genetic males can also have the condition. Dr. Dawn explains it's fundamentally an endocrine and metabolic disorder involving insulin resistance, elevated testosterone, and DHEA dysregulation. A study found that infrasound—low-frequency sound below human hearing range—elevated cortisol and worsened mood in subjects who didn't know and couldn't detect it was playing. Old buildings generate infrasound through aging boilers, ventilation ducts, and metal pipes, potentially explaining why, beyond autosuggestion, that old "haunted" houses feel spooky.
Send us Fan MailHow omega-3 fats in human health, including dietary intake needs, supplements, & omega fat testing.TOPICS DISCUSSED:ω-3 chemistry: EPA and DHA differ from plant ALA in chain length and double-bond count, making them structurally and biologically distinct — and largely irreplaceable by ALA conversion.ALA-to-EPA/DHA conversion: A small percentage of dietary ALA converts to EPA, and conversion to DHA is even lower; vegans rely on this inefficient pathway for all long-chain omega-3s.Cardiovascular mechanisms: ω-3s lower triglycerides, reduce platelet stickiness, improve endothelial function, and slow resting heart rate, reducing cardiovascular risk.ω-3 Index: Defined as red blood cell EPA+DHA as a percent of total fatty acids; 8–12% is the target range, while most Americans sit around 4–5%.Brain & dementia risk: Higher DHA blood levels are associated with significantly lower risk of dementia and Alzheimer's in large cohorts including the UK Biobank and Framingham.Linoleic acid nuance: Higher blood levels of dietary linoleic acid (omega-6) associate with lower dementia and cardiovascular risk; downstream omega-6 metabolites — not linoleic acid itself — associate with adverse outcomes.Supplementation practicalities: Most people need 1–2 g/day of EPA+DHA to reach an ω-3 Index >8%; oxidation concerns with fish oil supplements may be overstated.ABOUT THE GUEST: Bill Harris, PhD is founder of both OmegaQuant Laboratory and the Fatty Acid Research Institute (Sioux Falls, SD), where his work centers on blood fatty acid biomarkers as predictors of disease risk in large population cohort studies.KNOW YOURSELF:OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.RELATED EPISODE:M&M 134: Omega Fats, Vegetable & Seed Oils, Sugar, Processed Food, Metabolic Health & Dietary Origins of Chronic Inflammatory DiSupport the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts
Send us Fan MailHow dietary fatty acids regulate the initiation, propagation, and resolution of inflammation.TOPICS DISCUSSED:Parenteral nutrition history: IV nutrition evolved from soybean oil alone in the 1960s to complex blends including fish oil as the biology of ω-3s became understood.Three phases of inflammation: Initiation, propagation (driven by ω-6–derived prostaglandins and leukotrienes), and active resolution (driven by ω-3-derived resolvins and protectins).Pro-resolving mediators: Resolution is an active biological process, not passive; EPA and DHA generate resolvins and protectins that actively terminate inflammation.Aspirin's ω-3 mechanism: Aspirin inhibits arachidonic acid metabolism but allows EPA/DHA to access COX-2, upregulating pro-resolution mediators — a likely underappreciated mechanism of action.Cell membrane competition: EPA and DHA physically displace arachidonic acid in membranes, shifting the balance of mediators produced and improving resolution capacity.Linoleic acid & EPA synthesis: High linoleic acid intake saturates shared desaturase enzymes, inhibiting the body's conversion of ALA to EPA — meaning reducing ω-6 can raise ω-3 levels without supplementation.Dose & timing of ω-3 incorporation: ~2g/day of EPA+DHA shifts the arachidonic acid-to-EPA ratio enough to measurably reduce prostaglandin E2 production; white blood cells reflect changes within a month.ABOUT THE GUEST: Philip Calder, PhD is Professor of Nutritional Immunology in the Faculty of Medicine at the University of Southampton. His research focuses on how dietary fatty acids — particularly omega-3s — modulate immune responses and inflammatory processes across clinical and healthy populations.RELATED EPISODE:M&M 200: Dietary Fats & Seed Oils in Inflammation, Colon Cancer & Chronic Disease | Tim Yeatman & Ganesh HaladeSupport the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts
Don't skip homocysteine when testing for dementia risk factors; Treating osteoporosis; New hope against pancreatic cancer; Eating right for Parkinson's Disease; Olive oil helps stave off dementia—but only the right kind; A lifestyle hack that can cut Alzheimer's risk by 38%; How to reduce high calprotectin on a stool test.
Today’s episode of Ask the Dr. was an eye-opening deep dive into the truth about omega-3 fatty acids. Co-hosted by Dr. Michael Lange and Roger P. Schulman, we broke down the science behind omega-3 fish oil and why not all omega-3 supplements are created equal. We discussed the critical difference between rTG (re-esterified triglyceride) omega-3 and the inferior EE (ethyl ester) form. The rTG form is more natural, absorbs significantly better, and is less prone to oxidation—making it a superior choice for overall health. Key topics covered: Why omega-3 is an essential nutrient you must get from diet or supplementation The dangers of low-quality fish oil supplements (contaminants, poor absorption) How the right omega-3 supports heart health and may reduce atrial fibrillation risk The role of omega-3 in men’s prostate health Why form, purity, and dosage matter more than most people realize We also took live calls from listeners across the country, answering real-world questions and providing practical guidance. Special Offer Mentioned on Air: A limited-time 6-pack omega-3 bundle at 30% OFF + FREE shipping was offered during the show. If you care about your heart, brain, eyes, and overall longevity, this is a must-watch episode. Tune in weekly to Ask the Dr. — the longest-running live medical talk show in the country. #Omega3 #FishOil #HealthTruth #DrMichaelLange #AskTheDr #HeartHealth #ProstateHealth #AntiInflammatory #NutritionScience #Bioavailability #HealthyLiving #Longevity #SupplementTruth #Wellness #Omega3Benefits #Fortifeye #MedicalTalkShow #HealthPodcast #PreventativeHealth #BetterHealth #rtgomega3 #omegartgformSupport the show: https://www.drmichaellange.com/category/ask-the-doctor/See omnystudio.com/listener for privacy information.
Is oatmeal healthy?I have a higher-than-normal carotid artery intima-media thickness and no appreciable plaque. Should I be concerned?Should my husband and I take the hepatitis B vaccine?
I'm confused by information presented on diets containing meat as being dangerous. Could you shed some light?Assisted living models that would be of benefit to older adults
Expect a renewed push to take a statin at your next doctor's visit; PREVENT online calculator skews decisions to prescribe cholesterol reduction as early as 30; American Heart Association discourages at-risk patients from taking fish oil and garlic supplements—REALLY? Renewed interest in muscle as promoter of overall health and metabolism; The key role of urolithin A (Mitopure®️) for supporting muscle function. Is DHEA a reasonable supplement for post-menopausal women?
Would strontium help in the healing of lumbar fractures? How about as a preventive?How valuable is the hs-CRP test? Are there any drawbacks to eating canned fish?What are your thoughts on Arterosil for cardiovascular health?
The benefits of saunaThe Take Back Your Health TourA follow-up on milk thistle interactions with drugsWhat are your thoughts on low-dose saw palmetto for hair growth?Is monk fruit a safe sweetener to use?
Dr. Hoffman continues his conversation with Dr. Jeffrey Bland, Founder and President of the Personalized Lifestyle Medicine Institute and President of Big Bold Health.
Dr. Jeffrey Bland, Founder and President of the Personalized Lifestyle Medicine Institute and President of Big Bold Health, is described as the “godfather of functional medicine.” He details the origins of functional medicine as a systems-biology, root-cause approach emphasizing diet, lifestyle, and supplements alongside conventional allopathic care, especially for chronic disease. Bland contrasts medication “number needed to treat” examples (statins and TNF-alpha blockers) with personalized lifestyle interventions, noting adherence challenges. He discusses GLP-1 weight-loss drugs as a major pharmacologic advance but raises concerns about long-term effects, discontinuation rates, side effects, and inadequate nutrition if food intake drops. Bland describes research on bitter compounds and gut “taste” receptors influencing GLP-1 and related hormones, links to Blue Zone diets, and introduces Big Bold Health's Himalayan Tartary Buckwheat and minimally processed, sustainably sourced fish oil products, the Omega-3 index, and targeted formulations with lutein/astaxanthin, plus ongoing clinical trials on immune aging and gene expression.
Social media and AI—the digital equivalents of ultra-processed junk food--are undermining our brain power; Are natural non-caloric sweeteners—erythritol, xylitol and stevia—safe? A pig's brain has been flash frozen, and reanimated, signaling new prospects for cryopreservation after death; Dr. Jeffrey Bland weighs in on a new, enhanced form of fish oil from Big Bold Health.
What are your thoughts on peptides?So it's not possible to get enough protein from plants only?What about the downsides to animal protein?Are there any negative reports on the usage of extra virgin olive oil?Is it true that the nutritional value of farmed seafood is the same as wild caught?
Highlights from Dr. Hoffman's New Zealand bike tripDo you prefer whey protein isolate or concentrate?My liver enzymes went up taking a statin drug. My doctor recommends I take milk thistle. What are your thoughts?If any supplement protocols are out of stock, should we make substitutions?
whats wrong with me What's Actually Wrong With Me (And Why It Matters for Survival) | Episode 609 This One's a Little Different This is going to be a different kind of episode. If you're brand new, this might not be the best place to start. But if you've been listening for a while, you've probably heard me mention that something hasn't been right. Fatigue. Pain. Just feeling like absolute shit for months. And I finally have answers. I Thought It Was Just Getting Older For the longest time, I chalked everything up to getting older. I'm 44. I've got a physical job. I've got a six-year-old with the energy of a nuclear reactor. Of course I'm tired. Of course I hurt. That's what I told myself. But it kept getting worse. Getting off the couch became a chore. Playing with my daughter became something I physically couldn't do some days. That's when it stops being “just getting older.” The Long Road to a Diagnosis I tried a lot of things. Checked testosterone. It was low-ish, not terrible, but enough that I went on TRT. At first? I felt like a god. Two months in, energy through the roof, felt amazing. Then it all came back. Pain. Fatigue. Everything. That's when I knew something else was going on. I went through telehealth, got some blood work done, and one test came back just barely positive for something that could indicate lupus. Barely. Like right on the line. So I go to a rheumatologist. They run a ton of tests—vials and vials of blood—and we wait. Meanwhile, I'm feeding all this into ChatGPT, tracking symptoms, trying to figure it out. My wife is Googling like crazy, trying to prove it's not lupus. Because if you look up lupus? It's scary as hell. The Answer: Not One Thing—Two I finally sit down with the doctor and ask straight up: “With everything you've got… do you know what's wrong with me?” She didn't hesitate. Rheumatoid arthritis. And lupus. Both. There's even a name for it when they overlap—“rhupus.” Lucky me. Two autoimmune diseases. No cure. Something I'll be managing for the rest of my life. But here's the thing… Knowing is a huge weight off. Knowing Changes Everything Before, I was just throwing shit at symptoms. Trying supplements. Trying random fixes. Guessing. Now I know what I'm dealing with. Now it's not “what helps fatigue?” It's “what helps this specific condition?” That's a massive difference. Because now I can actually build a plan. The Reality of Living With It These diseases work in flares and remission. Some days are okay. Some days are bad. And some days you just have to ride it out. Right now, I've been in a pretty bad stretch. You've probably noticed episodes haven't been as consistent. That's why. I've felt like total garbage. What's Actually Helping (And What's Not) I've tried a ton of stuff. Most of it didn't do a damn thing. The one thing that has consistently helped me function? Kratom. Without it, I'm basically stuck. In pain. Not moving. With it, I can function closer to normal. And yeah, people have opinions about that. I get it. But when it's the difference between working and not working… that matters. Now I've been put on hydroxychloroquine, which is kind of the standard starting point for lupus. The downside? It takes months to fully kick in. Which sucks when you feel like garbage right now. I'll likely end up pushing for something like prednisone in the short term just to get relief while that builds up. Why This Matters for Prepping This ties directly into survival. If something goes wrong—real world, grid down, whatever—and I'm in a bad flare? I'm not protecting anybody. I'm not doing anything. That's a problem. Health is a prep. If you've got symptoms—fatigue, pain, weird stuff going on—go get checked. Because if you don't know what's wrong, you can't plan for it. And if you can't plan for it, it can take you out when it matters most. I know now that I'll likely be on medication long-term. So guess what? That becomes part of my preps. I'm not running out of something I need to function. That's not happening. Get Checked Before You Have To If you're dealing with symptoms and ignoring them, stop. Go to the doctor. Get blood work. Figure it out. Because this stuff doesn't just go away. And the longer it goes untreated, the worse it can get. Including permanent damage. You don't want to figure this out in the middle of a crisis. Handle it now. This has been James from SurvivalPunk.com. DIY to Survive. Amazon Item OF The Day AUVON XL Weekly Pill Organizer 2 Times a Day, Pill Box 7 Day with One-Side Large Openings for Easy to Use, Black Privacy Protection AM PM Pill Case for Medication, Vitamins, Fish Oils, Supplements Think this post was worth 20 cents? Consider joining The Survivalpunk Army and get access to exclusive content and discounts! Don't forget to join in on the road to 1k! Help James Survivalpunk Beat Couch Potato Mike to 1k subscribers on Youtube Want To help make sure there is a podcast Each and every week? Join us on Patreon Subscribe to the Survival Punk Survival Podcast. The most electrifying podcast on survival entertainment. Itunes Pandora RSS Spotify Like this post? Consider signing up for my email list here > Subscribe Join Our Exciting Facebook Group and get involved Survival Punk Punk's The post What's Actually Wrong With Me (And Why It Matters for Survival) | Episode 609 appeared first on Survivalpunk.
Most people buying "clean" supplements are unknowingly loading their bodies with heavy metals, rancid fish oil, and glyphosate, even inside products labeled organic and healthy. This episode breaks down exactly what the supplement industry refuses to tell you and gives you the tools to stop poisoning yourself every morning. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Grab a discount on Puori Products by visiting: https://puori.com/pages/dave?dt_id=1750934 Host Dave Asprey sits down with Oliver Amdrup-Chamby, founder and CEO of PUORI and a serial entrepreneur in the health and wellness space with over 16 years building what has become one of the most rigorously tested supplement brands in the world. Oliver opened the first CrossFit gym in Denmark in 2006, served as Regional Director of CrossFit HQ across Europe and the Middle East, holds an Executive Program credential from Stanford, and advises longevity projects including One Thirty Labs in Copenhagen. He founded PUORI in 2009 with a single obsession: creating the cleanest third-party tested fish oil on the market. That obsession grew into a full supplement line built on batch testing every finished consumer product for environmental toxins, a standard the industry has yet to catch up to. Together, Dave and Oliver expose the hidden contamination crisis inside the supplement industry, from oxidized fish oil that creates inflammation instead of fighting it, to plant-based protein powders carrying up to 10 times more heavy metals than whey. They break down why organic does not mean safe, how glyphosate embeds itself directly into your collagen infrastructure and disrupts the body's ability to build healthy connective tissue, and why the omega 3 index is one of the most powerful and measurable longevity biomarkers you are probably ignoring. They also dig into the surprising brain optimization and anti-aging benefits of creatine, including new research on concussion recovery and sleep deprivation, and how foundational supplements like vitamin D, magnesium, and high-quality fish oil remain the non-negotiables that no nootropic stack can replace. You'll Learn: Why organic protein powder often contains more heavy metals than non-organic options How glyphosate infiltrates collagen and gets rebuilt into your body's own tissue What the omega 3 index is, why most Americans are dangerously low, and how raising it correlates with years of additional longevity Why plant-based omega 3s fail to convert to DHA and what to take instead How oxidized fish oil creates inflammation rather than reducing it, and what to look for on the label Why vitamin D deficiency persists even with regular sun exposure and how genetics affect your required dose The creatine research that has longevity doctors and neuroscientists paying attention for the first time How foundational supplements support mitochondria, metabolism, and long-term resilience in ways that trendy biohacking stacks cannot replicate What to look for in a clean supplement brand and why third-party batch testing of finished goods is the only standard that matters Thank you to our sponsors! Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Oliver Amdrup-Chamby, PUORI supplements, fish oil oxidation, omega 3 index, heavy metals protein powder, glyphosate collagen, organic protein powder toxins, foundational supplements, creatine brain health, vitamin D deficiency, clean label testing, longevity supplements, biohacking, Dave Asprey, anti-aging, human performance, functional medicine, supplement transparency, plant-based protein heavy metals, whey protein Resources: • Grab a discount on Puori Products by visiting: https://puori.com/pages/dave?dt_id=1750934 • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 0:47 – Introduction 2:19 – Foundational vs. Sexy Supplements 4:33 – Omega-3 Index Explained 5:45 – Vegan Omega-3s & DHA 7:39 – Fish Oil Oxidation 8:48 – Batch Testing & Industry Transparency 16:03 – Storing Fish Oil Properly 17:30 – Vitamin D, Magnesium & Fish Oil Stack 19:11 – Vitamin D Dosing & Genetics 21:34 – RDAs & Government Nutrition Advice 23:06 – Glyphosate in the U.S. Food Supply 26:40 – Heavy Metals in Fish Oil 37:44 – Protein Powders & Heavy Metals 45:52 – Creatine for Brain & Concussion 48:48 – TrueDark & Brain Recovery 51:24 – Brain Scanning 53:58 – Toxins in Plant vs. Animal Protein 56:30 – Collagen: Sourcing & Glyphosate Risk 1:02:26 – Outro & PUORI Discount See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Shop all my verified, tested and preferred wellness products - includes most up to date brands: https://theswellscore.com/pages/drg Get My Brand Masterlist: https://drchristiangonzalez.com/best-brands-form-2-2/ Get Fish Oil Guide: https://drchristiangonzalez.com/fish-oil-pdf-request-form/ Episode Description 44 fish oil companies were asked one simple question. Most of them went silent. Fish oil is one of the most well-researched supplements on the market — but there's a side of the industry that never makes it onto the label. Fish oil oxidizes easily, bioaccumulates heavy metals, and can carry persistent organic pollutants like PCBs and dioxins. When the oil is rancid or contaminated, you're not just wasting money. You may be actively promoting the inflammation you're trying to fight. Dr. Christian Gonzalez contacted 44 fish oil brands and asked for one thing: independent third-party testing on the finished product. Real documentation. Proof. 37 companies ignored the request entirely. One refused. One opted out. Only five brands provided full transparency — and some of the biggest names in the category were nowhere to be found. In this episode, Dr. G covers: • How oxidation turns your fish oil from anti-inflammatory to pro-inflammatory • The heavy metals and contaminants you should always be testing for • Why potency on the label frequently doesn't match what's in the capsule • The five fish oil companies that earned a spot on the 2026 transparency list If you take fish oil daily, this episode will completely change how you shop for it. Timestamps: 0:00 - Intro 1:37 - Why Fish Oil Quality Actually Matters (Oxidation, Contamination & Potency) 3:52 - The 4 Standards Used to Evaluate Every Brand 6:44 - Companies That Partially Responded But Didn't Make the Cut 7:11 - Brands That Failed the Investigation (Full List) 7:54 - Recommended Brand #1 8:50 - Recommended Brand #2 9:35 - Recommended Brand #3 10:14 - Recommended Brand #4 11:16 - Recommended Brand #5 11:48 - Final Verdict: What This All Means for You Learn more about your ad choices. Visit megaphone.fm/adchoices
If you're only lifting weights to build muscle… you might be leaving serious gains on the table. In this episode, the guys break down why strength training alone isn't always enough, and how adding the right forms of cardio, mobility work, recovery, and even modalities like Pilates can actually improve muscle growth, performance, and longevity. They explain how your "gas tank" (cardiovascular fitness) can limit your strength, why mobility unlocks more muscle potential, and how tools like sauna use and recovery strategies can enhance results without overtraining. The conversation also expands into modern stress, community, and why human connection may be one of the most overlooked factors in overall health and resilience. Plus, they dive into new research on fish oil and mental health, and share some wild fitness and animal facts along the way. The Spring Bundle: Symmetry ($187), Prime ($107), Advanced Training Techniques Guide ($47) all for $147 (over 50% off) mapsmarch.com This episode is brought to you by KION ! ⇨⇨go to getkion.com/mindpump 20% off, No code needed automatically applied at check out! This episode is also brought to you by Troscriptions! ⇨⇨go to troscriptions.com/MINDPUMP Use code "MINDPUMP" for 10% off your first order What does Seed Daily Synbiotic do for you? Supports benefits in and beyond the gut——yes, Seed will support ease of bloating, healthy regularity, but it will also support your gut barrier, skin health, heart health, and micronutrient synthesis. Note: Gut immune function is not "boosting the immune system." It is about supporting the 'cross talk' between your intestinal cells and your immune cells. seed.com/mindpump Code "20MINDPUMP" for 20% off your first month of Seed's Daily Synbiotic 00:00 Intro 00:39 Sponsors, Promotions & MAPS Bundle 01:55 You're Leaving Muscle Gains on the Table 06:01 How Cardio Actually Improves Strength & Performance 10:19 Using Cardio as a Strategic Tool (Not Constantly) 11:36 Mobility, Range of Motion & Unlocking More Muscle 14:39 Recovery Hacks: Massage, Sauna & Performance Boosters 17:06 Can Pilates Help Build Muscle? Programming for Goals 22:27 Fish Oil, Stress & Modern Health Problems 25:17 The Real Reason We're More Stressed Today (Community Loss) 33:08 Why Human Connection Matters More Than Fitness 45:16 Sleep, Supplements, Random Facts & Dad Life Stories
In this Ask a Nutritionist episode, dietitian Alyssa Krejci explains the difference between fish oil and cod liver oil and how to choose the right one for your needs. Learn how omega-3 fats support heart, brain, and inflammation health, why EPA and DHA matter, and when cod liver oil's added vitamin A and vitamin D may or may not be helpful. Alyssa also shares simple tips for choosing a quality omega-3 supplement and getting more omega-3s from foods like salmon, sardines, and mackerel.
Dr. Hoffman continues his conversation with Neil Levin, the Senior Nutrition Education Manager and a product formulator for NOW(r) Foods and Protocol for Life Balance.
Nutritional Support for Brain Health: Lifestyle, Curcumin, Magnesium, and Key Nootropics: Nutrition educator/formulator Neil Levin from Protocol for Life Balance details nutritional support for brain health amid skepticism about “brain-boosting” supplements, citing a preprint randomized controlled trial using a multifaceted lifestyle plan (diet, exercise, sleep) plus targeted supplementation that reportedly improved and even reversed symptoms in people with mild cognitive impairment. They contrast lifestyle strategies with costly, side-effect-prone injectable “plaque-buster” Alzheimer's drugs and notes debate about whether amyloid is a root cause or byproduct. The conversation highlights inflammation and oxidation as major aging-related brain threats and reviews supplements including a brain-targeted curcumin (discussing bioavailability, delivery methods, blood–brain barrier crossing, and claims of lowering beta-amyloid protein), magnesium L-threonate for CNS delivery, phosphatidylserine and acetylcholine support (including huperzine), ginkgo and gotu kola, glutamine/GABA pathways, creatine, omega-3s (DHA/EPA and algae sources), B vitamins, acetyl-L-carnitine, alpha-lipoic acid, and cocoa flavanols, plus concerns about supplement industry enforcement.
Is what I've been doing for years helpful for achieving autophagy?When you say low carb, do you mean low complex carb or low simple and processed carb?What daily multivitamin would you recommend for a male age 50 plus?Which supplement should I take for elevated triglycerides?
Integrative Healthcare Symposium highlightsWhat supplements can help combat the side effects of cancer therapy?Will my son's use of Zepbound affect his fertility?
In this episode, Dr. Austin Rupp and I try to answer the following questions:Should patients with provoked VTE be offered long term anticoagulation if they have persistent risk factors, like obesity? Does coffee make atrial fibrillation worse (or better??)? Is age-adjusted d-dimer safe to use in DVT? Should we prescribe beta blockers after acute MI if the EF is normal?Does fish oil improve cardiovascular outcomes in patients on dialysis?What's the best approach for dialysis in patients with acute kidney injury?The articles:Extended Apixaban for Provoked VTE (HI-PRO)Coffee and Atrial Fibrillation (DECAF)Age-Adjusted D-dimer for DVT (ADJUST-DVT)Beta-blockers after MI with normal EFFish Oil in Dialysis Patients (PISCES)Conservative Dialysis in AKI (LIBERATE-D)Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R
Reflections on the Peter Attia/Epstein scandal; How to lower lp(a)—does diet help? What are bio-active peptides? Could they stave off kidney disease? Scientists just tested the fittest 81-year-old in the world—here's what they found; Media erroneously report that intermittent fasting is not effective for weight loss; Sugary drinks may stoke anxiety in teens; Omega-3s support kids' reading fluency and spelling scores; Surprising study shows saturated fats not harmful to kidneys.
Join us as we review and appraise recent practice-changing articles on oral semaglutide for obesity, fish oil in ESRD, IV iron during infection, the new US Dietary Guidelines, & anticoagulation after ablation in AFib. Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), Josh Gilman, & Matt Watto (@doctorwatto).Claim CME for this episode at curbsiders.vcuhealth.org!Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CMECredits Written and Hosted by: Rahul Ganatra MD, MPH; Paul Williams, MD, FACP, Joshua Gilman, MD, & Matthew Watto MD, FACP Cover Art: Rahul Ganatra, MD MPH Reviewer: Emi Okamoto, MD Technical Production: Pod Paste Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Show Segments Intro, disclaimer Oral Semaglutide for obesity Fish Oil for CV risk reduction in hemodialysis patients IV Iron for iron deficiency anemia during infection New USA Dietary Guidelines Anticoagulation after catheter ablation for AF Outro Sponsor: FIGSCheck out the limited-edition Team USA collection, and get 15 percent off your first order at Wearfigs.com with code FIGSRX. Sponsor: Continuing Education CompanyVisit CMEmeeting.org/curbsiders and use promo code Curb30 for 30% off all online courses and webcasts. Sponsor: GustoTry Gusto today at gusto.com/CURB, and get three months free when you run your first payroll.Sponsor: MDProgress For our listeners, enjoy your first month free at mdprogress.ca/promo/curbsiders
I know 2026 feels like it ihas been here for months, but only a few weeks ago we were celebrating the nephrology accomplishments of 2025. The New Filtrate came together to review the year.The FiltrateJoel Topf @kidneyboy.bsky.social (COI)Swapnil Hiremath @hswapnil.medsky.social and on LinkedIn Editor in Chief of Kidney International Case ReportsAnna Gaddy (@AnnaGaddy) Winner of NephJC Rookie of the Year 2020Nayan Arora (@CaptainChloride.bsky.social)AC (@medpeedskidneys.bsky.social)Vipin Verghese (@vipvargh.bsky.social) co-winner of NephJC Engaged Scientist of the Year in 2021Brian Rifkin (@brianrifkin.bsky.social) Co-Editor in Chief NephJC. Winner of NephJC Rookie of the Year 2021Cristina Popa (@NephroSeeker) Co-Editor in Chief NephJC. Wwinner of NephJC Rookie of the Year 2022 and MVP 2023Editing and Show Notes byAnna Gaddy and Joel TopfThe Kidney Connection written and performed by Tim YauShow NotesTop Stories in Nephrology 2025 (NephJC)First Top sories in Nephrology 2010! (Renal Fellow Network)Links to all of the Top Stories in Nephrology, hosted on NephJC since 2017 (NephJC)1. IgA NephropathyVISIONARY: Sibeprenlimab in IgA Nephropathy — Interim Analysis of a Phase 3 Trial (NEJM)ORIGIN 3: A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy (NEJM)APPLAUSE-IgA Alternative Complement Pathway Inhibition with Iptacopan in IgA Nephropathy (NEJM)Aliza M. Thompson, MD, MS (ASN) 2. Lupus NephritisREGENCY: Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis (NEJM)3. Nobel prize winner and peripheral immune tolerance4. Xenotransplantation5. GLP1ra RevolutionRemodel REMODELing mechanistic trials for kidney disease: a multimodal, tissue-centered approach to understand the renal mechanism of action of semaglutide (Kidney International)SURPASS-CVOT Tirzepatide vs. Dulaglutide Is Associated with Reduced Major Kidney Events in Patients with Type 2 Diabetes, CVD, and Very High-Risk Kidney Diseases (Kidney Week abstract in JASN)Poll: 1 in 8 Adults Say They Are Currently Taking a GLP-1 Drug for Weight Loss, Diabetes or Another Condition, Even as Half Say the Drugs Are Difficult to Afford (KFF survey)6. GDMT implementation in CKD: lessons learnt from CONFIDENCE and MIRO-CKDConfidence Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes (NEJM)MIRO-CKD Balcinrenone in combination with dapagliflozin compared with dapagliflozin alone in patients with chronic kidney disease and albuminuria: a randomised, active-controlled double-blind, phase 2b clinical trial (The Lancet)7. Flozin Meta analysisSMART-C. SGLT2 Inhibitors and Kidney Outcomes by Glomerular Filtration Rate and Albuminuria. A Meta-Analysis (JAMA)SMART-C. Effects of Sodium Glucose Cotransporter 2 Inhibitors by Diabetes Status and Level of Albuminuria. A Meta-Analysis (JAMA)8. Paradigm Shift: Aiming for CKD Remission9. Fish Oil and DialysisPISCES Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (NEJM)10. Decline in Dialysis Patients in the United StatesUSRD 2025 Annual Data Report (USRDS)Tubular SecretionSwapnil Hiremath Alien Earth on FX Hulu (Wikipedia)AC A Christmas Carol by Charles Dickens (Wikipedia) and The Muppet Christmas Carol (Wikipedia)Anna Monty Don (Wikipedia)Nayan Back Street Boys at The Sphere (Wikipedia)Brian Marty Supreme (Wikipedia)Cristina The Yellow Tie (Wikipedia)Vipin Stranger Things, good for a four year old? (Wikipedia)Joel Crash Course: The Universe with Katie Mack and John Green (Apple PodCasts)
The best omega-3 for your brain isn't fish oil. Discover the neuroprotective omega-3 that's been used for over 200 years for a variety of ailments, and as a potent source of vitamins A and D. Improve brain health and more with this powerful oil!
Episode Highlights With RobynHow she came to question supplements and how this led to a deep expose bookWhy what we call “vitamin D” as a supplement isn't actually vitamin D and why she questions taking itIt isn't just about good supplement vs bad supplement, but how to evaluate to know what's helpful and what's notWhy some vitamin D supplements have poison control warnings for pets When supplements are not just not helpful but directly harmfulThings to know about fish oil, rancidity, and what the metadata saysUnderstanding B vitamins and why many aren't what they seem eitherB vitamins don't exist in isolation in nature or in the body and most supplements are not made of any food substance but of chemicals Questioning vitamin C and iron Are minerals one of the few deficiency stories that's true due to overfarming?The one supplement she actually takes and whyResources MentionedTake Daily: How Supplements Hijack Your Health - Book Follow Robyn on Facebook, Instagram, and X
Kion Angelo Keely His main role with Kion. (2:01) How often do people cut corners? (4:05) The two paths with supplement companies —and why Kion chose the boring route. (9:10) Beating everyone with quality and education. (11:40) His greatest blind spot. (13:23) Essential amino acids vs. Whey protein powder for overcoming anabolic aging. (16:30) What makes one Omega-3 better than another? (24:10) The scientific breakdown of Omega-3s and why they are important to add to your diet. (26:08) How inflammation works, and how Omega-3s help the body heal faster. (29:44) Eating fish vs. taking a supplement, and what is the proper dose? (37:05) How to know if you have rancid fish oil. (39:12) Where they source their fish. (43:13) Busting the argument of the Omega-3 and 6s balance. (44:05) The two supplements that have a profound impact on longevity. (48:53) The hidden benefits of creatine. (49:41) The risks in the creatine space. (53:23) Leading from the front. (58:04) Methylation issues and creatine. (59:41) The Zion formula. (1:01:19) The BEST tasting coffee. (1:03:40) Top sellers. (1:10:00) Related Links/Products Mentioned Get 20% off Kion at getkion.com/mindpump Visit Pre-Alcohol by ZBiotics for an exclusive offer for Mind Pump listeners! ** Promo code MINDPUMP25 for 15% off first-time purchasers on either one-time purchases, (3, 6, 12-packs) or subscriptions (6, 12-pack) ** November Black Friday Deals (Nov. 1-15th): Sitewide 60% off. That includes every single MAPS program, bundle, MOD and guide. Enter the raffle now to win HUGE prizes: Bundles give you 10 entries, MAPS program gives you 3 entries, MODs or guides give you 1 entry. For programs go HERE. Enter the code BLACKFRIDAY at checkout. Mind Pump Store Use protein powder? New report reveals that some have high levels of lead Mind Pump # 2432: The Truth About Essential Amino Acids with Angelo Keely Stimulation of muscle protein synthesis with low-dose amino acid composition in older individuals Omega-3's could protect women against Alzheimer's New research reveals how creatine supports a sleep-deprived brain Mind Pump Podcast – YouTube Mind Pump Free Resources Featured Guest/People Mentioned Angelo Keely (@angelokeely) Instagram Website https://www.angelokeely.com/ Kion (@kion) Instagram Dr. William Seeds (@williamseedsmd) Instagram Featured Guest/People Mentioned Angelo Keely (@angelokeely) Instagram Website Kion (@kion) Instagram Dr. William Seeds (@williamseedsmd) Instagram