Podcasts about onchocerciasis

In this episode we will be hearing about a seven year research programme known as COUNTDOWN. COUNTDOWN consisted of multidisciplinary research teams across 4 countries- Ghana, Liberia, Nigeria and Cameroon and used co-production research approaches to improve the equity and efficiency of health systems interventions to control and eliminate seven Neglected Tropical Diseases. Research was implemented at each of the health system levels from policy to community and is all documented in the Journal ‘International Health' as a supplement entitled Stronger together: evidence for collaborative action on neglected tropical diseases. The supplement tells the story of how the programme engaged with people who have lived experience, health workers, and policy makers and really emphasises the importance of togetherness. Our guests today are Dr Luret Lar who was the programme manager employed by Sightsavers Nigeria, a collaborator on the COUNTDOWN programme, Dr Karsor Kollie who is the Program Director for Neglected Tropical Diseases at the Ministry of Health Liberia and Laura Dean from the Liverpool School of Tropical Medicine who was the Social Science lead for COUNTDOWN. Dr Laura Dean – Lecturer, Liverpool School of Tropical MedicineLaura has worked for the last 15 years in the use of participatory health research methodologies to support community and health systems development across sub-Saharan Africa and south Asia. Through participatory action research projects, she supports capacity strengthening within communities and health systems so that stakeholders can identify challenges and co-produce solutions. The majority of her work has focused on increasing inclusion and participation of people with lived experience of mental health conditions and chronic infectious diseases of poverty, for example neglected tropical diseases.Dr. Luret Lar - Medical Doctor, Public Health Physician, Lecturer, University of Jos, NigeriaLuret was involved in implementation research for seven years in collaboration with Liverpool School of Tropical Medicine when she was working for Sightsavers. Her interest and passion about preventive medicine and including the voices of the voiceless have influenced her research career over the years. Luret was interested in inclusivity at all levels of implementation in the neglected tropical diseases programme. This connected her with people affected by neglected tropical diseases and implementers at the community facility, state, and federal levels. She worked closely with these implementers to co-produce solutions to implementation challenges that everyone collectively identified.Karsor Kollie – Programme Director, Ministry of Health, LiberiaSince 2011, Mr Kollie has established and headed the Liberian Integrated NTDs Prevention and Control Programme and is based within the Ministry of Health and Social Welfare. He developed the NTD country master plan which forms the operational national guide for the next 5 years.Under his leadership the Liberian programme is making excellent progress in MDA control of Lymphatic Filariasis, Onchocerciasis, Schistosomiasis, Soil-transmitted Helminthiasis (STH) where treatment coverage has not gone below 75%, respectively. Alongside this, he is making significant progress in the development and application of new monitoring and evaluation criteria tailoring activities effectively with difficult on-the-ground terrain.More information can be found in the special supplement discussed in this episode: Stronger together: evidence for collaborative action on neglected tropical diseases | International Health | Oxford Academic (oup.com)Want to hear more podcasts like...

Dr. Ana Sikora, Infectious Diseases Fellow at the University of South Florida Division of Infectious Diseases, presents a review of lesser known tropical infectious diseases syndromes. Dr. Sikora begins by discussing the epidemiology of tropical diseases, and then prioritizes the most important ones based upon WHO categorization. Syndromes discussed includes Drucunculiasis, lymphatic filariasis, Onchocerciasis, soil transmitted helminths, and Schistosomiasis. Lastly, the process by which international organizations such as the WHO coordinate efforts to control or eradicate these syndromes is briefly discussed.

Ready to really feel your skin crawl? Then this month's episode on Onchocerca volvulus, a parasite that is able to infiltrate into the eye and skin to cause intense itching and blindness, might just be the one for you! We'll learn all about why this communicable disease earned the nickname "River Blindness", its mysterious linkage to seizures, the awesome powers of ivermectin (when it's actually used for diseases it can treat), and how exactly a donkey falling into a river has helped hundreds of thousands of people. Tune in to learn more about the epidemiology, biology, and history of this infectious disease! Website: www.infectiouscast.com Twitter: @infectiouscast Instagram: @infectiouscast

Contributor: Don Stader, MD Educational Pearls: Ivermectin is a Nobel-Prize winning antiparasitic  used to treat filariasis and onchocerciasis Ivermectin is receiving press due to a scientific study examining ivermectin on COVID-19 viral replication in vitro, but the dosages needed for this effect were much higher than is safe for human use Ivermectin has since been studied in humans with no evidence suggesting it is a viable treatment for COVID-19 Ivermectin is a neurotoxin but at normal levels it does not cross the blood-brain barrier Ivermectin toxicity can include altered mental status, seizures, coma, tachycardia, hypotension, nausea, vomiting and diarrhea Treatment of suspected ivermectin overdose is predominately supportive References Caly L., Druce J.D., Catton M.G., Jans D.A., Wagstaff K.M. The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. Antivir Res. 2020;178:104787. doi: 10.1016/j.antiviral.2020.104787 López-Medina E, López P, Hurtado IC, et al. Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19: A Randomized Clinical Trial. JAMA. 2021;325(14):1426–1435. doi:10.1001/jama.2021.3071 Roder JD, Stair EL. An overview of ivermectin toxicosis. Vet Hum Toxicol. 1998;40(6):369-370. Roman YM, Burela PA, Pasupuleti V, Piscoya A, Vidal JE, Hernandez AV. Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials [published online ahead of print, 2021 Jun 28]. Clin Infect Dis. 2021;ciab591. doi:10.1093/cid/ciab591 Chandler RE. Serious Neurological Adverse Events after Ivermectin-Do They Occur beyond the Indication of Onchocerciasis?. Am J Trop Med Hyg. 2018;98(2):382-388. doi:10.4269/ajtmh.17-0042 Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD   The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account.  Donate to EMM today! Diversity and Inclusion Award

In this classic TPWKY episode we travel down rivers and into worm-laden nodes as we take a look at the complex world of Onchocerca volvulus, the vector-borne parasite that causes river blindness. Join us as we learn why the name ‘river blindness’ captures only one dimension of the devastation caused by this parasite, how the short evolutionary history of this worm is at once surprising and enlightening, and why grasping the disease ecology of this system has been crucial in successful control efforts. As a bonus, if you tune in, you’ll get to hear how on earth The J. Geils Band fits into this story and the integral role that dog digestion has played in the history of this parasite. See omnystudio.com/listener for privacy information.

In this twisted, maddening parody of a Terminus episode, we review only brutal death metal and raw pagan black metal. If you like elegant tremolo leads, immersive atmospheres, or vast, epic compositions, you are shit out of luck -- here you will find only viscous desolation and savage blades. For once, we let The Death Metal Guy off the leash at the beginning of the show, and what does he do? Using phrases like "a lattice-work of slams",* he makes a systematic case for the artistic importance of brutal death. For you lovers of single-minded, extremely inaccessible sound, there's the Phillipine band Exerminated. Will Genesis of Genocide be the BDM album that finally sends The Black Metal Guy running for the hills? Next up, it's far more BM-positive fare from the cool dudes in Onchocerciasis Esophagogastroduodenoscopy, whose cacophonous mangle of eerie dissonance and iron snare evokes the monstrous angelic forms of Neon Genesis Evangelion (see T2 for a review of their last record). On the second half of the show, TBMG unleashes our arsenal of short-release reviews, with: 1. A high-concept split release by Panzerwar (see T22) and Lungtoucher, centered on the clash of Saxons and Norsemen in what is now Yorkshire, northern England. 2. A promising demo from Spanish (no, Catalan!) newcomer Turment Nocturn. If you're worn out from hearing TDMG obsessively analyze complicated death metal riffs, get ready for TBMG to obsessively analyze some of the simplest riffs we've ever had on the show. 3. Finally, the booted berserkers of Doppelaxt raise their doppelaxen high above the mountain of the slain, offering red tribute to the black banner of PABM (PENNSYLVANIA BLACK METAL, that is). This band has learned the wolven mysteries of 90s Poland, but strikes with a hardcore-punkish speed that could only come from North America.   00:00 - Introductory bullshitting 0:06:14 - Exterminated - The Genesis of Genocide (Comatose Music) 0:49:34 - Onchocerciasis Esophagogastroduduodenoscopy - The Rotted Plinth of Sachiel (Stillbirth Records)** 1:33:13 - Interlude - Cephalotripsy - "Consummating Omophagia," fr. Uterovaginal Insertion Of Extirpated Anomalies (Amputated Vein Records, 2007) 1:38:59 - Panzerwar / Lungtoucher - The Battle of Jórvík split (Independent) 2:23:46 - Turment Nocturn - Sense Misericordia (Narbentage / Negra Nit) 2:44:33 - Doppelaxt - Kill the Opposition (Independent / Cassettes thru to Signal Rex) 3:11:39 - Outro - Doppelaxt - “My Journey Towards Idealism,” fr. Kill The Opposition *TDMG credits this to the excellent oldschool RYM reviewer Syncline. **TDMG accidentally says that their 2020 EP, Adoration of Decaying Innocence, was their first official release. In truth, that was a 2019 demo called, uh, Interspecies Defloration.   Terminus links: Terminus on Youtube Terminus on Patreon Terminus on Subscribestar Terminus on Instagram Terminus on Facebook thetrueterminus@gmail.com

It's a stomach-churning hypothesis based on previous research: The kinds of worms that affect hundreds of millions of people, mostly in the tropics, may be mitigating the most severe effects of COVID-19. Listen to DW's science podcast for a different angle on the coronavirus — five minutes every day from Germany.

Second run of a new podcast focused on extreme metal. Today, it's blasting war metal vs. brutal death metal -- which will reign supreme? What is the art of deliberately obnoxious music? How can a band move forward without compromising on primitive noise? What's the difference between BM and DM extremity? 00:00 - Introductory bullshitting / rundown of bands and labels 04:45 - Revenge, Strike. Smother. Dehumanize. Stomps, pick slides, and clearer production. 19:35 - Axis of Advance, Strike. Revenge returns to their melodic roots? 32:28 - Impiety, Versus All Gods. Fast hybrid riffs, the problem with thrash, Shyaithan Stays True. 53:45 - Surrender of Divinity, Oriental Hell Rhythmics. Southeast Asian Extremity. Swords vs. sledgehammers. 59:35 - Onchocerciasis Esophagogastroduodenoscopy, Adoration of Decaying Innocence. What makes a good slam? Why don't people count this stuff as avant-garde? 01:15:45 - Other nasty, antisocial music (Mutiilation, Ildjarn) 01:21:10 - Encenathrakh - Live. Art guys do brutal DM right. Music as "object" vs. music as "process." Death metal inhumanity vs. black metal inhumanity.

Dr. Horn reviews several important tropical diseases, including Chagas disease (caused by Trypanosoma cruzii), spread by the Triatomid bug, African Trypanosomiasis, the cause of sleeping sickness, Cystercercosis, caused by the Pork tapeworm, and Buruli ulcer. He closes by discussing Onchocerciasis and its effect on significant areas of the developing world.

It’s the second episode of Infested! Let’s dive into an insect everyone loves to hate and a disease that will make your skin crawl. Yep,  we are talking about pesky blackflies and the almost-eradicated disease they transmit: River blindness! Buckle in for all the entomology & vector-borne disease goodness along with a global health tale showing the value of vector control and multinational cooperation. Women for Women International Books  Comstock, J. H. (1949). An introduction to entomology. Retrieved from http://archive.org/details/introductiontoen1949coms Peer Reviewed Journal Articles Boussinesq, M. (2018). A new powerful drug to combat river blindness - The Lancet. The Lancet, 392(10154), 1170–1172. https://doi.org/10.1016/S0140-6736(18)30101-6 Hall, L. R., & Pearlman, E. (1999). Pathogenesis of Onchocercal Keratitis (River Blindness). Clinical Microbiology Reviews, 12(3), 445–453. Lamberton, P. H. L., Cheke, R. A., Walker, M., Winskill, P., Crainey, J. L., Boakye, D. A., … Basañez, M.-G. (2016). Onchocerciasis transmission in Ghana: the human blood index of sibling species of the Simulium damnosum complex. Parasites & Vectors, 9(1), 432. https://doi.org/10.1186/s13071-016-1703-2 Nicholls, R. S., Duque, S., Olaya, L. A., López, M. C., Sánchez, S. B., Morales, A. L., & Palma, G. I. (2018). Elimination of onchocerciasis from Colombia: first proof of concept of river blindness elimination in the world. Parasites & Vectors, 11(1), 237. https://doi.org/10.1186/s13071-018-2821-9 Thiele, E. A., Cama, V. A., Lakwo, T., Mekasha, S., Abanyie, F., Sleshi, M., … Cantey, P. T. (2016). Detection of Onchocerca volvulus in Skin Snips by Microscopy and Real-Time Polymerase Chain Reaction: Implications for Monitoring and Evaluation Activities. The American Journal of Tropical Medicine and Hygiene, 94(4), 906–911. https://doi.org/10.4269/ajtmh.15-0695 Turner, H. C., Walker, M., Lustigman, S., Taylor, D. W., & Basáñez, M.-G. (2015). Human Onchocerciasis: Modelling the Potential Long-term Consequences of a Vaccination Programme. PLOS Neglected Tropical Diseases, 9(7), e0003938. https://doi.org/10.1371/journal.pntd.0003938 Our Social Media Follow us on Instagram and Twitter @Infestedpodcast Follow Lindsay on Twitter @Baxter.Lindsay Email us at Infestedpodcast@gmail.com This Podcast is produced and edited and researched by Lindsay and Bailey. Their views and opinions are theirs and do not reflect the institution for which they are employed. The music for this episode was provided by Lee Rosevere.   

Dr. Karp and Dr. Daniel Shungu discuss Onchocerciasis, also known as river blindness (Recorded April 28th, 2019).

The TWiP triptych solve the case of the 9/11 Survivor infested with parasites, and discuss the effect of community ivermectin treatment for onchocerciasis on Loa loa infections. Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiP. Links for this episode: Ivermectin for onchocerciasis and loiasis (PLoS NTD) Hero: William Boog Leishman Thanks to Caitlin for the image Letters read on TWiP 159 Case Study for TWiP 159 Going back to India, gentleman in 20s seen during rainy season in south. Week of feely achy, fever, severe pain in right upper part of belly. Vomiting, no diarrhea. Married, no children, works indoors in trades - electrician. Drinks large amount of palm date liquor. Previously healthy, no allergies, no medical issues. No travel. On exam: right lung base decreased breath sounds; upper right area of belly can feel liver coming down. Area of intercostal tenderness. Elevated white count; left shift, eosinopenic, alk phos up. Chest xray: shows effusion in right base. Ultrasound of liver: fluid filled single lesion. Lesion aspirated. Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees

Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin The TWiP Masters solve the case of the Australian Wildlife Carer, and review evidence that nodding syndrome may be caused by an autoimmune reaction to the parasitic worm that causes river blindness. Become a patron of TWiP. Links for this episode: Nodding syndrome an autoimmune disease? (Sci Transl Med) Nodding syndrome: Preventable and treatable (Sci Transl Med) River Blindness lyrics (Google Play) Image credit Letters read on TWiP 129 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase - WITH FREE SHIPPING - by going to blueapron.com/twip. Case Study for TWiP 129 Young male in 30s, presents to ER with male partner, NY area, chief complaint over 1 month significant diarrhea, watery, non bloody. Abdominal cramping. Feels poorly, low energy, fever. Some vomiting, lost noticeable amount of weight, can’t stay hydrated. Past: AIDS positive, not on meds, last CD4

Vincent, Dickson, and Daniel solve the case about the man from El Salvador, discuss the use of tyrosine kinase inhibitors to treat onchocerciasis and filariasis. Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin Links for this episode: Targeting filarial tyrosine kinases (J Inf Dis) Onchocerciasis on TWiP 24 Filariasis on TWiP TWiP 25 Image shows c-abl kinase bound to imatinib (red) Image credit What good are ticks? Letters read on TWiP 94 Case study for TWiP 94 Daniel's patient was seen in the clinic. He is a 33 yo chinese male, from Chinatown NYC, for several months on and off has had watery diarrhea, headaches. Tried reflexology, chiropractic therapy, with no results. Has traveled quite a bit, been in Chile (was there a few months before). Came to US when young. Grew up in the US. In Chile, has had many sexual partners, >50, of both sexes, also has done many drugs. Two years ago was diagnosed with chronic HIV, CD4 count 685, on ARVs triple therapy, virus loads are well controlled. Has had syphilis, nose job, no medication allergies. Lives with family. On exam, afebrile, looks well. Symptom onset a few months after last Chile visit. Is an addventurous eater.  Send your diagnosis to twip@twiv.tv Contact Send your questions and comments (email or mp3 file) to twip@twiv.tv Subscribe Subscribe to TWiP (free) in iTunes, by the RSS feed or by email  

In the dense forests of Uganda, the fight against river blindness follows an especially challenging mission. Watch public health specialists from The Carter Center as they journey to the black fly's breeding area, discover how freshwater crabs play a unique role in the life cycle of the insect, and learn how dedicated field workers devote tireless efforts to the demanding job of eradicating the fly and the terrible disease it carries. 10/1/2008

In the dense forests of Uganda, the fight against river blindness follows an especially challenging mission. Watch public health specialists from The Carter Center as they journey to the black fly's breeding area, discover how freshwater crabs play a unique role in the life cycle of the insect, and learn how dedicated field workers devote tireless efforts to the demanding job of eradicating the fly and the terrible disease it carries. 10/1/2008

An overview of the Carter Center's battle against river blindness.