Podcasts about Indication

Jeanie Buss Reveals LeBron James Has Given No Indication He Wants to Stay With the Lakers Next Season, Kyrie Irving Takes a Subtle Shot at LeBron Over His Answers During a Press Conference Learn more about your ad choices. Visit megaphone.fm/adchoices

In this second part of our polypharmacy discussion with Steve Williams, we continue to explore whether large language models like Microsoft Copilot could play a practical role in supporting medication reviews. We consider a real case from a duty day in general practice where Copilot was used to assess prescribing safety and generate a summary of deprescribing opportunities. This prompt was used: “Review the following medication list using the latest British Geriatrics Society (BGS) guidance and the Scottish Polypharmacy Guidance (7-step approach). For each medicine, identify: Indication and whether it is still appropriate Clinical risks (frailty, falls, anticholinergic burden, renal function, interactions) Deprescribing opportunities Safer alternatives if applicable Monitoring requirements Then provide a concise summary of priority actions and any safety red flags that need urgent review. Here is the medication list: [PASTE MEDICATIONS HERE]  Include references to the relevant guideline steps where appropriate.” The conversation also covers a new study led by Professor Tony Avery, which tested an LLM against an expert clinician to assess medication safety in nearly 300 anonymised GP patient records. While the model achieved 100% sensitivity in detecting clinical issues, it matched the expert's full assessment in under half of cases, with failures arising from overconfidence, lack of contextual reasoning, and occasional hallucinations such as misidentifying medications. Steve is self-described as a “curious pragmatist” and feels that LLMs are of great interest, and their ability to flag problems with high sensitivity - when guided by good prompts and established clinical frameworks - makes them a genuinely useful preparation tool, provided the clinician still does the thinking. As Steve puts it, the technology looks promising, but "human intelligence is very underrated..." A Real-World Evaluation of LLM Medication Safety Reviews in NHS Primary Care. Evidence Based Polypharmacy Reviews and the 7 Step Process: TURAS training Thinking Critically About AI (Video lecture by Dr Jessica Morley) How we make decisions – dual process theory and unconscious biases (MeReC Bulletin 2011) You can subscribe to the SNUG podcast on the following platforms: SNUG podcast on Apple podcasts      SNUG podcast on Spotify

Five articles from the February 2026 issue summarized in five minutes, with the addition of a brief editorial commentary. The 5-in-5 feature is designed to give readers an overview of articles that may pique their interest and encourage more detailed reading. It may also be used by busy readers who would prefer a brief audio summary in order to select the articles they want to read in full. The featured articles this month are: Intraoperative Zoledronic Acid for Arthroscopic Rotator Cuff Repair: Short-Term Results From a Prospective, Randomized, Placebo-Controlled Phase II Trial Dermal Allograft Augmentation for Open Gluteus Medius Repair: A Case Series at 2-Year Follow-up Prediction of Contralateral Patellar Instability After Ipsilateral Medial Patellofemoral Ligament Reconstruction Arthroscopic Primary Labral Reconstruction in the Hip: Minimum 10-Year Outcomes With a Nested Propensity-Matched Control Using a Residual Pivot Shift as the Indication to Perform a Lateral Extra-articular Tenodesis During ACL Reconstruction Using Autologous Hamstring Grafts Is Associated With Improved Surgical Outcomes: A Retrospective Review of 4755 Cases Click here to read the articles.

Few surgeons in the world combine the depth of clinical experience and academic rigor that Dr. Waldemar Polido brings. A Professor and practicing Oral Maxillofacial Surgeon in Indianapolis, he began his dentistry education in Brazil and has since built a career at the forefront of complex implant surgery. In this conversation, Dr. Polido shares his three-part implant philosophy, systematic surgical approach, and the evolution of solutions for patients with severe maxillary atrophy. We also explore common surgical complications, strategies for prevention, grafting techniques, and the post-operative processes that ensure long-term success. Packed with insights from a highly experienced and knowledgeable guest, this episode is essential listening for oral maxillofacial surgeons seeking to expand their mastery of zygomatic implants.Key Points From This Episode:Dr. Polido's education, surgical residency, and academic background.His three-part philosophy on implantology as influenced by Brånemark. Four systematic concepts that support his approach to long-lasting implants. How Dr. Polido's approach towards determining which solution to use has evolved. Reducing complications during zygomatic implant surgery.Where grafting typically comes in during the implant process.Post-op processes for pain control and follow-up. Foreseeing and addressing complications during surgery. Advice on how oral maxillofacial surgeons can learn more about zygomatic implants.Predictions for the next 15 years of implant dentistry.Rapid fire questions: Dr. Polido's best read of the past year and more. Links Mentioned in Today's Episode:Dr. Waldemar Polido on LinkedIn — https://www.linkedin.com/in/waldemardpolido/ Dr. Waldemar Polido on Instagram — https://www.instagram.com/prof.waldemarpolido/ Dr. Waldemar Polido Email — wdpolido@iu.edu Dr. Per-Ingvat Brånemark — https://www.branemark.se/branemarklegacy Indiana University School of Dentistry — https://www.dentistry.iu.edu/ The SAC Classification in Implant Dentistry — https://www.iti.org/the-sac-classification-in-implant-dentistry ZAGA Centers — https://zagacenters.com/ Dr. Carlos Aparicio — https://www.apariciozygomatic.com/ E. Armand Bedrossian on LinkedIn — https://www.linkedin.com/in/e-armand-bedrossian-dds-msd-facp-7752b8184/ Pikos Institute — https://www.pikosinstitute.com/ Complexitiez — https://www.complexitiez.com/ AAOMS — https://aaoms.org/ All Physicians Lead — https://www.amazon.com/All-Physicians-Lead-Redefining-Leadership/dp/B0CN2RG5F7 Do You Feel Like I Do?  — https://www.amazon.com/Do-You-Feel-Like-Memoir/dp/0316425311 Landman — https://www.imdb.com/title/tt14186672/F1: The Movie — https://www.imdb.com/title/tt16311594/ Adolescence —

Barham Abu-Dayeeh introduces endoscopic gastroplasty, discussing its background, indications, and relevance alongside GLP-1 inhibitors.

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From ginger shots and lentil crisps to sparkling bone broth and cinnamon water, the hosts hit the floor at 2026 Winter FancyFaire* in San Diego to sample what's next in food and beverage. The hosts discuss standout brands, innovative concepts, smart packaging and evolving brand strategies that reveal where wellness, snacking and functional drinks are headed. Show notes: 0:25: Toll Booth. Talk On Camera. Ginger Boost. Cravable Crisps. New Jerk. Bone Broth What? Chips & Cherries. –  At the Taste Radio booth at the 2026 Winter FancyFaire* in San Diego, the hosts highlight Elevator Talk interviews recorded at the show and praise the event's energy, accessibility, and balance of early-stage and established brands. They also spotlight trends like functional wellness, clean-label snacks, and innovative packaging. They sip on Solti's turmeric and ginger shots, before snacking on Paro's new lentil crisps and discussing the brand's move into more mainstream offerings. The hosts also sample Pulpito's new fruit bars, and Morro's unconventional sparkling bone broth. They also feature standouts products, from a portable squeeze-pack peanut butter and Indian-inspired coffee drinks to better-for-you popsicles, cinnamon-infused water, and a variety of functional and indulgent snacks. Brands in this episode: Solti, Starbucks, Paro, Maazah, Masala Bliss, Pulpito, Solely, Marro, By Nutz, Yeri, Dew Dropper, Rabbit Foods, Tru Cinnamon, Burlap & Barrel, Bitchin' Sauce, The Coconut Cult, Tart, Cheribundi, Todo, Date Better, Baba's, Habiza, Dirty Saint

Midweek Check-in.

KMOX Religion Editor Fred Bodimer chats with Pew Senior Researcher Greg Smith about religion and young people in the United States.

In this episode of K9's Talking Scents, Cameron Ford sits down with world-renowned trainer Michael Ellis for one of the most in-depth conversations ever recorded on reinforcement theory, over-arousal, odor commitment, reward schedules, and why many detection dog programs unintentionally create false alerts.Together they break down the problems behind “reward-rich” training systems, how reinforcement can become punishing, why omission matters, and how to build dogs who persist, stay committed to odor, and search with accuracy — even in operational environments where rewards rarely come.This episode covers:• Why dogs become toy-obsessed instead of odor-committed• How handlers accidentally create false alerts• Why “continuous reinforcement” destroys operational reliability• Rewarding search vs rewarding finds• The science of frustration, dopamine, and over-performance• The difference between learning behavior and maintaining behavior• Why real-world deployments MUST be represented during training• How to introduce blanks, variable schedules, and expectation violation• "Satan's Infinite Loop" and how trainers build bad habits into dogs• Why many dogs don't indicate because they want the search to continue• How to build persistent, reliable, stable detection dogsIf you're a detection dog handler, trainer, supervisor, or K9 program manager, this is a masterclass.CHAPTERS00:00 — Intro & catching up01:00 — Online education & training libraries02:00 — Are rewards harming performance?05:00 — Reinforcement vs intrinsic motivation07:00 — Over-arousal in detection dogs08:30 — Searching for toys vs searching for odor10:00 — False alerts & frustration12:00 — The “cheat code” problem14:30 — Reward-rich environments vs real deployments17:00 — Continuous vs variable reinforcement19:00 — Training that mirrors real-world operations21:30 — Expectation violation & handler discomfort23:00 — Why easy training creates weak dogs26:00 — Dogs that quit vs dogs that persist28:00 — Reducing rewards without breaking the dog30:30 — Reading search behavior correctly32:00 — Consistency in training fundamentals35:00 — Foundation errors that create future problems38:00 — When to introduce blanks41:00 — Reinforcing end-of-search behaviors44:00 — Fixing continuously rewarded dogs47:00 — Why dogs miss the first odor49:00 — Over-arousal & compensation behaviors52:00 — Indication obsession & unintended consequences54:00 — Odor recognition vs sit/down behavior57:00 — Natural indications & reading the dog59:00 — Satan's Infinite Loop explained________________________________________

AMJ Podcast | Episode 4 Capivasertib in the Clinic: Strategies to Manage Adverse Events This content was funded by AstraZeneca, and is intended for US Healthcare Professionals. Expert opinions are shared in this program and may differ from the approved capivasertib (TRUQAP®) labeling. Please see full Prescribing Information, including Patient Information when making treatment decisions.     Indication and Usage  Capivasertib (TRUQAP®) in combination with fulvestrant is indicated for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN alteration as detected by an FDA-approved test following progression on at least one endocrine-based regimen in the metastatic setting or recurrence on or within 12 months of completing adjuvant therapy.     Description In this practical, case-based discussion, a breast oncology pharmacist and nurse practitioner walk through how they anticipate and manage the most common adverse events seen with capivasertib in HR-positive/HER2-negative advanced breast cancer. Drawing on real-world clinic workflows, they share stepwise approaches to counseling, prophylaxis, and early intervention for diarrhea, rash, and hyperglycemia, including when to escalate monitoring or treatment and how to coordinate roles across the care team.  You'll hear communication scripts, tips for using tools such as stool diaries and home glucometers, and strategies to keep patients on therapy safely and confidently.   Chapters 00:00 – 03:24 | Introduction 03:24 – 05:18 | When to consider capivasertib 05:18 – 08:51 | Introducing adverse events 08:51 – 16:18 | Diarrhea management 16:18 – 20:35 | Rash management 20:35 – 25:07 | Hyperglycemia management 25:07 – 27:31 | Care team best practices 27:31 – 31:18 | Top Tips & Takeaways   Speakers: Heather Moore –  Breast Oncology Pharmacist, Duke University Medical Center Sarah Donohue – Breast Oncology Nurse Practitioner, UCSF Health Breast Care Center     Select Safety Information About capivasertib (TRUQAP®) tablets TRUQAP is contraindicated in patients with severe hypersensitivity to TRUQAP or any of its components. Serious adverse reactions include hyperglycemia, including diabetic ketoacidosis and fatal outcomes; diarrhea; and cutaneous adverse reactions. Monitor fasting glucose and hemoglobin A1C levels regularly. May cause fetal harm when administered to a pregnant woman. Among the 355 patients who received TRUQAP in CAPItello-291, the most common (≥20%) adverse reactions, including laboratory abnormalities, were diarrhea (72%), cutaneous adverse reactions (58%), increased random glucose (57%), decreased lymphocytes (47%), decreased hemoglobin (45%), increased fasting glucose (37%), nausea and fatigue (35% each), decreased leukocytes (32%), increased triglycerides (27%), decreased neutrophils (23%), increased creatinine (22%), vomiting (21%), and stomatitis (20%). Please see full Prescribing Information, including Patient Information for TRUQAP.

Modi's Big Indication - Action on Mu$lims & Isl@m to Begin | Amit Shah in Action Mode |Sanjay Dixit

The FDA requests boxed warnings be removed from HRT product labels; Caplyta approved for MDD; Darzalex Faspro gains new indication; investigational MS treatment looks promising; trial investigates simplified HIV regimen.

TJ Lateef's first game as a starting QB was excellent----he really didn't look rattled at any time, and led 4 TD scoring drives, plus the impressive drive to close the game out. 13/15 passing , 205 yards, 3 TDs (no INTs or fumbles); 5 carries, 31 yards You can't say after one game that he's the guy of the future---what you can say is that he goes to Penn State and wins and is a big reason why and they beat Iowa as well…then it HAS to get interesting at that spot. That's drama that should be welcomed.  Show Sponsored by MIDWEST BANKOur Sponsors:* Check out Avocado Green Mattress: https://avocadogreenmattress.com* Check out Hims: https://hims.com/EARLYBREAK* Check out Infinite Epigenetics: https://infiniteepigenetics.com/EARLYBREAK* Check out Uncommon Goods: https://uncommongoods.com/EARLYBREAK* Check out Washington Red Raspberries: https://redrazz.orgAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Dr. Francis Marchlinski, Deputy Editor of JACC: Clinical Electrophysiology, discusses Electrode Thermal Profile During Ventricular RF Ablation: A novel indication to potentially inform energy delivery.

Our Browns beat reporter Daryl Ruiter joined "Baskin and Phelps" Thursday, and gives the state of the Browns with the Steelers game in Pittsburgh coming up in three days, along with why talks of a "fire sale" coming in Cleveland is not the case.

Welcome to this special episode of the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. For major FDA decisions in the field of neurology, we release short special episodes to offer a snapshot of the news, including the main takeaways for the clinical community, as well as highlights of the efficacy and safety profile of the agent in question. In this special edition of Mind Moments, Patricia Pozo-Rosich, MD, PhD, head of the neurology department at Vall d'Hebron University Hospital, discussed the recent FDA approval of fremanezumab (Ajovy) for pediatric migraine prevention. As a study author on the pivotal phase 3 SPACE trial (NCT03539393), Dr. Pozo-Rosich reflected on the significance of having a proven therapeutic option in a population where placebo responses and lack of evidence have long complicated care. She provided insights on how the trial was designed and the challenges of running pediatric studies, particularly in adolescents. Additionally, she highlighted broader implications for migraine research, including efforts to reduce placebo effects, the role of CGRP pathway inhibition in younger patients, and the future promise of emerging targets such as PACAP antagonists and new toxin formulations. For more of NeurologyLive's coverage of fremanezumab's expanded indication in pediatric migraine, head here: FDA Approves Fremanezumab as First Anti-CGRP Preventive Therapy for Pediatric Episodic Migraine Episode Breakdown: 1:10 – Initial reaction to fremanezumab approval and significant for pediatric migraine care 6:05 – Major clinical insights and takeaways from phase 3 SPACE trial 10:20 – Challenges in pediatric migraine trials and addressing high placebo responses 15:10 – Future directions in migraine therapy, including PACAP-targeting drugs and novel approaches Thanks for listening to the NeurologyLive Mind Moments podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

"McElroy & Cubelic In The Morning" airs 7am-10am weekdays on WJOX-94.5!See omnystudio.com/listener for privacy information.

Listen to a conversation with Durand Jones, Aaron Frazer and Blake Rhein of the soul band Durand Jones and The Indications. They joined WFYI's Kyle Long for an in-depth discussion of their roots in Bloomington, Indiana and how projects including the IU Soul Revue and Charlie Patton's War brought the band together. The Indications' latest album is titled “Flowers”, and they'll be performing in Indianapolis on September 30 at the Hi-Fi Annex.  Durand Jones and the Indications formed in Bloomington in 2012, while its members were studying at Indiana University. The band's sound was built around a mutual love for classic soul, funk and R&B. Their reputation spread beyond Bloomington in 2016, when Ohio's Colemine Records issued their debut album. The Indication's second album “American Love Call” was issued in 2019 and praised by critics for its lush arrangements and socially conscious lyrics, earning comparisons to The Impressions and The Delfonics. Two years later, their album “Private Space” debuted in the Top 10 of Billboard's Emerging Artists chart. Their latest album “Flowers” builds on the band's distinct blend of vintage soul sounds and contemporary production techniques. Since launching in Bloomington over a decade ago, The Indications have grown into an international force, racking up millions of streams online, and touring across North America and Europe.

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After shoplifting $1500 worth of merchandise, including 21 bottles of probiotics, from three different pharmacies, 32-year-old Tyler Jones was pulled over for riding his bike at night without a light. HE thought they wanted him for the thefts, which they did when the first thing he said was "I didn't do it."See omnystudio.com/listener for privacy information.

Hear Christopher McKim's journey with moderate to severe plaque psoriasis and the latest clinical trial results from dermatologist, Dr. Christine Cornejo. Join this discussion with moderator Archie Franklin as Christopher McKim, a BMS employee living with moderate to severe plaque psoriasis, and Dr. Christine Cornejo, Director and US Medical Engagement Lead for Dermatology and Rheumatology at BMS, offer a patient and physician's perspective on treating plaque psoriasis from the inside. Listen as Chris presents his journey along with Dr. Cornejo addressing effectiveness and safety information with clinical trial results for a prescription oral treatment option. The intent of this episode is to encourage those who have moderate to severe plaque psoriasis to work with their health care provider to find a treatment option that is right for them. This episode is sponsored by Bristol Myers Squibb. For more information view Full Prescribing Information and Medication Guide . ·       (0:00)   Intro to Psoriasis Uncovered and guest welcome to Bristol Myers Squibb employee and patient Christopher McKim and Dr. Christine Cornejo, Director and US Medical Engagement Lead for Dermatology and Rheumatology at Bristol Myers Squibb. ·       (2:15)  Where the journey to finding the right treatment option for Chris and his moderate to severe plaque psoriasis began.  ·       (3:09)   The decision by Chris and his provider to try an oral systemic medication. ·       (3:28)  The effects and impact of an oral systemic treatment for Chris and his plaque psoriasis. ·       (4:09)   Dr. Cornejo addresses efficacy and clinical trials results. ·       (5:58)   Common side effects and safety concerns for the treatment Chris and his health care provider decided to try.   ·       (6:28)   Health considerations patients and providers should discuss prior to using a systemic treatment.    ·       (6:54)   What to do should side effects occur. ·       (7:10)   How Chris feels with clearer skin after making a change in treatment. ·       (8:14)   Indication and Important Safety Information. Key Takeaways: ·       Moderate to severe plaque psoriasis is a systemic disease.    ·       If you're ready to treat from the inside there is a treatment option that may help.   ·       Work with a health care provider to find the right treatment for moderate to severe plaque psoriasis.   ·       Be proactive by taking steps to learn about treatment options including effectiveness, side effects, safety concerns, and what should be discussed with a health care provider before beginning a new treatment for plaque psoriasis.  Guest Bios:   Christopher (Chris) McKim joined BMS in June of 2022. In his current role he is a Regional Marketer for the dermatology division, prior to that he provided support for 9 Therapeutic Area Specialists for the Pacific South District in the GI division.  Prior to joining BMS, Chris worked at Sanofi, J&J, Leo Pharma, and Sun Pharma in various field and home office roles. Chris resides in beautiful San Diego with his family Susan (wife), Morgan 18, Maddy 16, Mason 14 and two Golden Retrievers and enjoys traveling, cooking and anything associated with the ocean (Deep Sea Fishing, S.C.U.B.A. diving, snorkeling, and boogie boarding). Dr. Christine Cornejo joined Bristol Myers Squibb in 2024 as Director, Medical Engagement Lead for Dermatology and Rheumatology. Prior to joining BMS, she practiced dermatology at Brigham and Women's Hospital and Dana-Farber Cancer Institute in Boston, MA, where she specialized in melanoma and high-risk skin cancer management and served as the Director of Confocal Microscopy. She also served as an Instructor at Harvard Medical School and led the Immunology and Infectious Diseases course for 1st year medical students. Resources: Current Oral Systemic Treatments For additional questions about treatment options contact the NPF Patient Navigation Center

New indication for Kerendia; investigational therapy shows promise for hypertension; Novolog interchangeable biosimilar gets approval; trial results for hormone-free contraceptive; Shingrix now supplied in a prefilled syringe.

Fix delivered! My interview with Dark Indication! We discuss the new album and much more!!!

Mike Johnson, Beau Morgan, and Ali Mac continue the final hour by spending some time with 92.9 The Game's own Braves insider and reporter, Grant McAuley! Beau, Mike, Ali, and Grant discuss if Grant thinks the Braves could trade Sean Murphy at the trade deadline, what Grant expects from the Braves after the All-Star break, how Grant felt about Spencer Strider's start last night, Grant Holmes putting together a really good 2025 season, Grant Holmes not getting any run support this season, what Grant is most excited about for All-Star Weekend here in Atlanta, and who Grant is looking forward to talking to the most out of all of the 2025 MLB All-Stars.

Matthew 25:31–46

Phil Steele top 60 has Utah at #18 and BYU at #53 60 in 60 Watchlist - Broc Lane - USU TE | Good, Bad & Ugly Whole World News

Nucala gains new indication; the FDA are set to require placebo-controlled trials to evaluate COVID-19 vaccines; pruritus reported following discontinuation of antihistamines; oral carbapenem antibiotic looks promising for cUTIs; investigational celiac disease Tx gets Fast Tracked

 We are less than two weeks away from the start of Thom's Australia visit. We have a range of tour events scheduled, including free introductory talks and a learn to meditate course for those who are new to Vedic Meditation. If you've completed a qualified Vedic Meditation course, we invite you to join Tom for knowledge sessions, group meditations and a one-day retreat he has scheduled in Sydney.  Thom is also offering a five-day four-night retreat in Gerringong, south of Sydney, as well as private mentoring sessions throughout the month.  You can find out more about all of these offerings at thomknoles.com/sydney. Detachment is frequently sold as a necessary step for spiritual progress. We're taught that attachment is often the root of our suffering, so it stands to reason therefore, that detachment will bring about the opposite of suffering.But as Thom explains in this podcast episode, it's an understandable yet inaccurate conclusion that actually causes more suffering.Thom brings clarity to the subject, using the Vedic concept of vairagya, a state of being that allows us to fully enjoy the fruits of life, without the bondage of attachment.Episode Highlights[00:45] Maharishi Patanjali's Yoga Sutras[02:56] Siddhis - Developing Extraordinary Human Capabilities[05:36] A Spontaneous State of Non-attachment[09:48] A Witnessing Phenomenon[12:55] A Consequence of the Practice of Vedic Meditation[16:23] An Indication of Cosmic Consciousness[19:08] The Freedom of Spontaneous Non-attachmentUseful Linksinfo@thomknoles.com https://thomknoles.com/https://www.instagram.com/thethomknoleshttps://www.facebook.com/thethomknoleshttps://www.youtube.com/c/thomknoleshttps://thomknoles.com/ask-thom-anything/

Livestock market analyst Kyle Bumsted recaps factors impacting Wednesday's trade, where livestock traded lower and wheat led the grains higher. Topics: - Cattle start higher, end lower - Technical/chart damage - Indication of cash trade? - Hogs meander around - Algos move wheat - Basis perception vs. reality

Pirates insider John Perrotto comes on The Fan Hotline to talk to fill-in host Jason Mackey about how he perceives the team as the end of April approaches.

He was born in Siberia in 1797 to a clerical family, and became a married parish priest in Irkutsk. A devout explorer, John Kriukov, told him of the great spiritual needs among the Russian and native peoples in Alaska, then Russian territory. Moved to serve Christ in this very difficult environment, he and his family arrived in Alaska in 1824. He quickly learned the Aleut language and worked humbly and tirelessly among the Aleuts. His spiritual classic, An Indication of the Way to the Kingdom of Heaven, was originally written in Aleut and later translated into many languages.   While he was visiting Russia in 1838, his wife died; one year later he was tonsured a monk and given the name of Innocent (he had been Fr John Veniaminov). Almost immediately after his tonsuring he was, without warning, raised to the rank of Bishop of all Eastern Siberia and Russian America, probably the largest diocese in the world at that time. Returning to Alaska, he continued his missionary work with vigor, often traveling among Aleut and Tlingit settlements in his own kayak. Wherever he went, he found the Alaskan people hungry for the faith, and his labors bore rich fruit which is still obvious today: Alaska has more Orthodox churches per capita than any other state.   In old age he was made Metropolitan of Moscow, head of the entire Russian Orthodox Church. His concern for Christian mission was undiminished, and as Metropolitan he created the Orthodox Missionary Society. He reposed on Holy Saturday of 1879.

He was born in Siberia in 1797 to a clerical family, and became a married parish priest in Irkutsk. A devout explorer, John Kriukov, told him of the great spiritual needs among the Russian and native peoples in Alaska, then Russian territory. Moved to serve Christ in this very difficult environment, he and his family arrived in Alaska in 1824. He quickly learned the Aleut language and worked humbly and tirelessly among the Aleuts. His spiritual classic, An Indication of the Way to the Kingdom of Heaven, was originally written in Aleut and later translated into many languages.   While he was visiting Russia in 1838, his wife died; one year later he was tonsured a monk and given the name of Innocent (he had been Fr John Veniaminov). Almost immediately after his tonsuring he was, without warning, raised to the rank of Bishop of all Eastern Siberia and Russian America, probably the largest diocese in the world at that time. Returning to Alaska, he continued his missionary work with vigor, often traveling among Aleut and Tlingit settlements in his own kayak. Wherever he went, he found the Alaskan people hungry for the faith, and his labors bore rich fruit which is still obvious today: Alaska has more Orthodox churches per capita than any other state.   In old age he was made Metropolitan of Moscow, head of the entire Russian Orthodox Church. His concern for Christian mission was undiminished, and as Metropolitan he created the Orthodox Missionary Society. He reposed on Holy Saturday of 1879.

President Donald Trump on Friday awarded Boeing the contract to build the U.S. Air Force's future fighter jet. The Next Generation Air Dominance program will replace Lockheed Martin's F-22 Raptor with a crewed aircraft built to enter combat alongside drones. Trump, the 47th president, said the new jet will be called the F-47. Meanwhile, Trump has denied a New York Times report that Elon Musk was due to be briefed by the Pentagon today about the U.S. military's plan for any war that might break out with China.British police say there is no indication so far of foul play related to a blaze at an electrical substation that led to the closure of London's Heathrow airport, though counterterrorism detectives are leading the investigation into its cause.

Vrabel decided to spend all the money on defense. Is the Patriots tight end group even that good? Revisiting the Bill Belichick weird photo. Jones in impressed with Bill's quads. Who took the picture? Back to the Sox. Today could be a good indication of Kampbell making the team. What does that mean for David Hamilton? Random college basketball player. Jones and Keefe get stumped. Clip of the day

Most commonly the challenge is gaining lean muscle. Doing all the things but can't seem to gain muscle? Then tune in and go through this like a check list of 12 strength training mistakes in menopause that could be the reason. It just takes one. But if there are multiple, it's compounded and in this case, not interest but penalty! Join us at Metabolism Makeover 2.0 to support your journey avoiding the 12 strength training mistakes in menopause. Overworking Small Muscle Groups [00:02:20] You need fewer of these small muscle group-focused exercises in your routine if you prioritize the major muscles like chest (pectoralis) and back (trapezius and Latissimus Dorsi). If the secondary (biceps and triceps) muscles are going to get a workout most of the time, these will rob you of time and energy that is better spent on major muscles if you aren't getting in the adequate volume there. Skipping the Warmup [00:06:40] Nearly a decade ago, I began sharing the fact that if you skip the warmup, you also miss an opportunity to increase total energy expenditure during a workout. It's not only about injury prevention. There's an increased blood circulation, improved energy expenditure, mobility and you can work closer to your capacity. If fitness and longevity are truly goals, “exercising” is not the same as working at your capacity and safely, sanely raising the roof on your fitness level so that age doesn't automatically result in slowing down or gaining weight. Not Resting Between Sets Long Enough Before [00:13:10] Rapidly moving from one exercise to the next, was yesterday. The “metabolic conditioning workouts” are a nice anomaly, a change in pace. Rest between sets of strength training. Reach complete muscle fatigue or within 2 reps of it. If you do HIIT, separate the sessions so you get the best benefit from it and from strength. If you are not getting stronger, not increasing muscle, and these are your goals (in order, perhaps to improve body fat % ultimately), it's a “how” you're doing it problem. Plan Your Routine to Avoid 12 Strength Training Mistakes in Menopause No Organized Plan [00:17:30] You either default to using what's available at the gym or doing the same exercises in the same sequence every time. If you're not careful you won't change the stimulus (by changing the sequence and sets/rep combination) and may also not be getting enough sets per muscle group in each week. It doesn't mean that all sets for a muscle group must be all the same exercise. A super set of 6 different exercises for the triceps works. The next workout you may just do 3 and you're still covered… if you planned it that way. Not Sleeping Enough or Not Changing the Workout When You Don't Sleep [00:20:50] The sleep you get will determine the benefit you get from exercise. If you don't prioritize, your workouts will suffer too. You're also at risk for injury, not only because your body isn't fully doing the repair job or releasing testosterone and growth hormone in deep cycles of sleep as it should, but because coordination suffers. Treating Soreness or Worn Out an Indication of “Good Workout” [00:22:40] When you work muscles, it's normal to feel sore, even if you're extremely fit. Some muscles like quads and glutes are used to a lot of activity and tend to get sore less often. But there are two genes associated with soreness and you may either be predisposed to be sore or not. It's not a good indication of whether you worked hard enough. If you reached muscle fatigue or came close, you gave the muscle enough stimulus. The first sign of poor recovery was soreness after workouts, the second was reduced performance during workouts. 12 Strength Training Mistakes in Menopause to Avoid and Nurture Your Body Dependence on Supplements and Negating Balanced Whole Food Meals. [00:27:00] If you're all too willing to jump to EAAs, or BCAAs but won't eat regular meals that result in satiety, chances are your lack of micro and macronutrients will catch up with you. “Food first”, then allow supplements to take you the rest of the way. I don't like to “count” calories on a regular basis but a snapshot is very helpful for checking in. Often for knowing when you're eating too little. Taking Too Much Advice (or Too Little From Too Many People) [00:30:20] It often takes even gurus a while to come around. You have to love Vonda Wright and Mary Haver sharing their own menopause journeys. We need more women like them. They're open about not knowing what they didn't know about menopause, as physicians and women. You have at your fingertips access to women who learned the hard way, so you don't have to. Just don't jump in the middle. You need an onramp. Ignoring Nutrition Needs. [00:32:30] The talk is “calorie deficit.” Yet, 80% of women in our community under-eat for their mere existence (resting metabolic rate) and then try to put their foot on the accelerator for exercise causing a bigger caloric deficit. Then they stay there for years, under-fed and under-fueled (processed food, diet food), the metabolism will come to a halt, along, potentially with adrenal and thyroid function. Figure your calorie needs. Use an app to track your actual intake for 3-5 days. 12 Strength Training Mistakes in Menopause That Hinder Your Progress Thinking Small, Skinny, or Numbers That Don't Matter Instead of That Do [00:36:20] Your size and your weight on the scale do not tell the story of your fitness and health. Though they might hint at your likelihood of sarcopenia and osteoporosis, fall and fracture risk. When women focus on weight or size they sacrifice muscle. When they lose muscle, they lose strength, longevity and independence. A woman who has her ideal weight or size is constantly thinking about it and a step away from a fall or fracture. A fracture that results in bedrest, weakness and loss of more muscle. The beginning of the end. Those falls are not devastating just because of the breaks, but because of brain bleeds or other internal damage. Too Heavy to Start [00:38:20] The first 6-8 weeks, and up to 12, of a resistance training program, the benefits are due to the neural connection. That isn't rushed by going heavy. But loads too great for your ligaments, tendons and joints or muscles can cause weakness, undue soreness, and a weak foundation leading to injury. We, in the fitness industry, need to be more careful. We have sometimes lost our way in regard to where to START, and how and at what pace to PROGRESS. You Add Something But Don't Remove Something Else [00:40:30] I've experienced this temptation myself. When I started training for triathlons at 40, I was compelled to figure out how to run even while I was adding biking or swimming to my schedule. I soon realized I was sabotaging the quality of every workout and just putting those “junk miles.” A woman will lose muscle because of the added stress, inability to recover. That's an extreme example, but if you're adding and never subtracting/replacing, you're probably going to experience similar results. References for the 12 Strength Training Mistakes in Menopause: For dropping in the references.. Ideally just the single line link.. Vs long for the podcasts and posts - however if the research is really: within last 10 years, features female subjects.. Then it should be added to the research document. Nothing else should ever be used in our content. #1 Cheng AJ, Jude B, Lanner JT. Intramuscular mechanisms of overtraining. Redox Biol. 2020 Aug;35:101480. doi: 10.1016/j.redox.2020.101480. Epub 2020 Feb 26. PMID: 32179050; PMCID: PMC7284919. #2 Afonso J, Brito J, Abade E, Rendeiro-Pinho G, Baptista I, Figueiredo P, Nakamura FY. Revisiting the 'Whys' and 'Hows' of the Warm-Up: Are We Asking the Right Questions? Sports Med. 2024 Jan;54(1):23-30. doi: 10.1007/s40279-023-01908-y. Epub 2023 Sep 2. PMID: 37658965; PMCID: PMC10798919. #3 https://pubmed.ncbi.nlm.nih.gov/19691365/#:~:text=Conversely%2C some experiments%20have%20a demonstrated,be%20safer%20and%20more%20reliable #4 Hughes SL, Seymour RB, Campbell RT, Whitelaw N, Bazzarre T. Best-practice physical activity programs for older adults: findings from the national impact study. Am J Public Health. 2009 Feb;99(2):362-8. doi: 10.2105/AJPH.2007.131466. Epub 2008 Dec 4. PMID: 19059858; PMCID: PMC2622796 #4 Brickwood KJ, Ahuja KDK, Watson G, O'Brien JA, Williams AD. Effects of Activity Tracker Use With Health Professional Support or Telephone Counseling on Maintenance of Physical Activity and Health Outcomes in Older Adults: Randomized Controlled Trial. JMIR Mhealth Uhealth. 2021 Jan 5;9(1):e18686. doi: 10.2196/18686. PMID: 33399541; PMCID: PMC7815450. #5 https://www.somnologymd.com/2024/09/sleep-womens-health/ #6 Romero-Parra N, Maestre-Cascales C, Marín-Jiménez N, Rael B, Alfaro-Magallanes VM, Cupeiro R, Peinado AB. Exercise-Induced Muscle Damage in Postmenopausal Well-Trained Women. Sports Health. 2021 Nov-Dec;13(6):613-621. doi: 10.1177/19417381211014134. Epub 2021 May 27. PMID: 34039086; PMCID: PMC8558998. #6 https://sheffieldphysiotherapy.co.uk/muscle-soreness-mean-youve-effective-workout/ #7 & #9 Erdélyi A, Pálfi E, Tűű L, Nas K, Szűcs Z, Török M, Jakab A, Várbíró S. The Importance of Nutrition in Menopause and Perimenopause-A Review. Nutrients. 2023 Dec 21;16(1):27. doi: 10.3390/nu16010027. PMID: 38201856; PMCID: PMC10780928. #7 Lentjes MAH. The balance between food and dietary supplements in the general population. Proc Nutr Soc. 2019 Feb;78(1):97-109. doi: 10.1017/S0029665118002525. Epub 2018 Oct 30. PMID: 30375305; PMCID: PMC6366563 #10 Martinez, B.P., Batista, A.K.M.S., Gomes, I.B. et al. Frequency of sarcopenia and associated factors among hospitalized elderly patients. BMC Musculoskelet Disord 16, 108 (2015). https://doi.org/10.1186/s12891-015-0570-x #10 Sakuma, Kunihiro, Yamaguchi, Akihiko, Sarcopenic Obesity and Endocrinal Adaptation with Age, International Journal of Endocrinology, 2013, 204164, 12 pages, 2013. https://doi.org/10.1155/2013/204164 #11 Kraemer WJ, Ratamess NA. Fundamentals of resistance training: progression and exercise prescription. Med Sci Sports Exerc. 2004 Apr;36(4):674-88. doi: 10.1249/01.mss.0000121945.36635.61. PMID: 15064596 #12 Caplin A, Chen FS, Beauchamp MR, Puterman E. The effects of exercise intensity on the cortisol response to a subsequent acute psychosocial stressor. Psychoneuroendocrinology. 2021 Sep;131:105336. doi: 10.1016/j.psyneuen.2021.105336. Epub 2021 Jun 18. PMID: 34175558. #12 Woods NF, Mitchell ES, Smith-Dijulio K. Cortisol levels during the menopausal transition and early postmenopause: observations from the Seattle Midlife Women's Health Study. Menopause. 2009 Jul-Aug;16(4):708-18. doi: 10.1097/gme.0b013e318198d6b2. PMID: 19322116; PMCID: PMC2749064. https://pmc.ncbi.nlm.nih.gov/articles/PMC2749064/#:~:text=Early laboratory studies of hot,in our earlier report5. Resources: 5 Day Flip: https://www.flippingfifty.com/5-day-challenge-new/ Lunges: Love 'em or Leave 'em https://www.flippingfifty.com/lunges-muscles-squats-variations-benefits Protein Products: https://www.flippingfifty.com/protein Other Episodes You Might Like: How to Exercise with High or Low Cortisol in Menopause: https://www.flippingfifty.com/high-or-low-cortisol-in-menopause 8 Strength Training Mistakes Wasting Your Time (fix them): https://www.flippingfifty.com/8-strength-training-mistakes Fit or Fat? Training and Measuring Fitness in Menopause: https://www.flippingfifty.com/measuring-fitness-in-menopause

Sources are telling CNN that authorities have executed as many as three search warrants in New York as part of their investigation into the killing of UnitedHealthcare CEO Brian Thompson. At least two of the warrants include the backpack found in Central Park and the burner phone found near where the shooting occurred, according to a law enforcement source with knowledge of the investigation. Anderson shares what we have learned so far, and what we still don't know about the suspect. Plus, what the White House said today about the mysterious drones flying at nighttime over many parts of New Jersey. Learn more about your ad choices. Visit podcastchoices.com/adchoices

NORTH KOREA: Indication of Russia sharing technology. Bruce Bechtol, author, "North Korean Proliferation in the Middle East and Africa. 1950 Korean War

GOOD EVENING: The show begins tonight in Caracas, where there is strong indication that the regime will survive ... 1924 Caracas CBS EYE ON THE WORLD WITH JOHN BATCHELOR FIRST HOUR 9-915 #NewWorldReport: Venezuela  escapes again.  Latin American Research Professor Evan Ellis, U.S. Army War College Strategic Studies Institute. @revanellis #NewWorldReportEllis https://www.reuters.com/world/americas/us-says-it-has-not-offered-maduro-amnesty-since-election-2024-08-12/ 915-930 #NewWorldReport: Sinaloa Double Cross. Latin American Research Professor Evan Ellis, U.S. Army War College Strategic Studies Institute. @revanellis #NewWorldReportEllis hcttps://www.reuters.com/world/americas/mexican-drug-lord-el-mayo-zambada-says-he-was-ambushed-new-account-us-arrest-2024-08-10/ 930-945 #NewWorldReport: Ecuador in extreme peril. Latin American Research Professor Evan Ellis, U.S. Army War College Strategic Studies Institute. @revanellis #NewWorldReportEllis https://www.reuters.com/world/americas/ecuador-ex-president-correas-party-taps-luisa-gonzalez-presidential-candidate-2024-08-10/ 945-1000 #NewWorldReport: #AMAZON: The fires surge & What is to be done?   Latin American Research Professor Evan Ellis, U.S. Army War College Strategic Studies Institute. @revanellis #NewWorldReportEllis 24-08-11/ https://www.reuters.com/business/environment/brazil-fire-brigades-fight-amazon-blazes-off-torrid-start-2024-2024-08-09/ http SECOND HOUR 10-1015 #Ukraine:  The incursion and the risk.  Colonel Jeff McCausland , USA (retired) @mccauslj @CBSNews @dickinsoncol https://www.telegraph.co.uk/world-news/2024/08/14/ukraine-russia-war-latest-news21/ 1015-1030 #Hezbollah: War warning.  Colonel Jeff McCausland , USA (retired) @mccauslj @CBSNews @dickinsoncol https://www.telegraph.co.uk/world-news/2024/08/14/israel-netanyahu-defence-chiefs-ceasefire-talks-iran-hamas/ 1030-1045 #UK: King Charles stands up for England: PM Starmer does not. Simon Constable, Occitanie. https://www.msn.com/en-us/news/world/king-charles-delay-in-condemning-u-k-riots-draws-criticism/ar-AA1oscxd C 1045-1100 #RUSSIA: Suitcases of Euror and dollars, big bills. Michael Bernstam, Hoover Institution https://www.msn.com/en-us/money/companies/nearly-all-chinese-banks-are-refusing-to-process-payments-from-russia-report-says/ar-AA1oLZjY THIRD HOUR 1100-1115 1/2: #GEORGIA: SOUTH CAUCASUS: Balancing act between Moscow and Brussels teetering. Ekaterina Zolotova in Moscow, @GPFutures https://geopoliticalfutures.com/in-georgia-balancing-east-and-west-gets-tougher/ 1115-1130 2/2: #GEORGIA: SOUTH CAUCASUS: Balancing act between Moscow and Brussels teetering. Ekaterina Zolotova in Moscow, @GPFutures https://geopoliticalfutures.com/in-georgia-balancing-east-and-west-gets-tougher/ 1130-1145 #SPACEX: Delayed by the FAA. Bob Zimmerman BehindtheBlack.com https://behindtheblack.com/behind-the-black/points-of-information/faa-cancels-scheduled-public-meetings-to-review-new-boca-chica-environmental-assessment/ 1145-1200 #MARS: The joyful dodgy report of an underground ocean.Bob Zimmerman BehindtheBlack.com https://behindtheblack.com/behind-the-black/essays-and-commentaries/more-bad-journalism-this-time-about-a-hypothesized-underground-ocean-on-mars/ FOURTH HOUR 12-1215 PRC: Orbital bomber and anti-satellite platform called ShenLong. Brandon Weichert, author of Winning Space: How America Remains a Superpower, on @GordonGChang, Gatestone, Newsweek, The Hill: https://www.independent.co.uk/space/china-secret-space-plane-europe-b2595354.html 1215-1230 #PRC: UKRAINE; Savvy China investors in Ukraine: Rebecca Grant, vice president of the Lexington Institute@GordonGChang, Gatestone, Newsweek, The Hill https://www.newsweek.com/china-breaks-silence-ukraine-kursk-offensive-1937859 1230-1245 #TAIWAN: IOC permits bashing Taiwanese patriots. Stephen Yates, chair of the America First Policy Institute's China Policy Initiative,@GordonGChang, Gatestone, Newsweek, The Hills: https://www.nbcnews.com/news/world/flags-banned-taiwan-olympics-chinese-taipei-rcna165502 1245-100 am PRC: High end manufacturing illusions: Andrew Collier, managing director of Orient Capital Research and author of new book, China's Technology War: Why Beijing Took Down Its Tech Giants, @GordonGChang, Gatestone, Newsweek, The Hill: https://www.globalsourcepartners.com/posts/view-from-washington/teaser?utm_campaign=elts&utm_medium=social&utm_source=social https://www.wsj.com/economy/trade/chinas-nightmare-a-second-trade-war-with-trump-363313ae