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Naš najbolj prijazen pokrovitelj T2 vam predstavlja vesolje e športa v Odiseji, dobrodošli:https://www.t-2.net/vesolje-e-sporta-v-odisejiFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
Y con nuestro estimado, Alan Estrada, productor, actor e influencer; damos inicio a la Segunda Temporada de tu espacio favorito "El rincón de los errores"Disfruta de este episodio y conoce sobre el maravilloso error de enamorarse, seguramente amarás este episodio como los de la segunda temporada.¡Bienvenidxs a la T2! Hosted on Acast. See acast.com/privacy for more information.
In this episode of "Financial Crime Matters," Kieran talks with AUSTRAC CEO Brendan Thomas about his agency's efforts to implement a vast extension of Australia's anti-money laundering regime to about 80,000 new entities under legislation commonly referred to as T2. In service to those efforts, Brendan details AUSTRAC's outreach to law firms, accountants, real estate agencies and other designated non-financial businesses and persons who will be required to create an anti-money laundering (AML) risk analysis, appoint an AML officer and be ready to file suspicious matters reports by July 2026. Key to Australia's need to come into compliance with the Financial Action Task Force's global standards, the extension of AML regulation is also central to the country's plan to actually stem the flood of illicit funds from transnational crime organizations into Australia's banking, gaming, real estate, precious metals and other sectors, Brendan says. As part of its commitment to effectuate more fund seizures and prosecutions, Brendan discusses how the AUSTRAC initiative will also utilize public-private information sharing, embodied by the country's Fintel Alliance, increased staffing, and AI and other technological tools to weaponize what will ultimately be 100,000 anti-financial crime reporting entities under T2.
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba paket T-2 TV+NET.https://www.t-2.net/paketi/t2-tvnetFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
It's my birthday, and I'm spending it crafting cards on Sorare with 15K essence! The big question: will we land in any T2+ or Special Star rooms?Come hang out live as I rip through my essence stash, see what rewards we can unlock, and celebrate the day with the Sorare community. Whether we hit something huge or not, it's all about the fun — and the birthday vibes.⚽️ Want to join Sorare? Use my link to get up to $150 in market credits (Terms and conditions apply): https://sorare.pxf.io/WyLBnZ⚠️ Affiliate Disclosure: I am a Sorare affiliate, which means I may benefit if you use my referral link. Nothing in this stream should be considered financial advice.
An overview of Magnetic Resonance Imaging (MRI), beginning from the basic physics of nuclear magnetic resonance, and covering the use of radiowaves to excite nuclear spin states, and the T1 and T2 modes of relaxation. We then explore how these phenomena are used to produce 3d images, including magnetic field gradients, frequency encoding, phase encoding, and Fourier transforms. We conclude with a discussion of functional imaging, including the haemodynamic response, the BOLD signal, echo planar imaging, and the steps of preprocesing. Recommended pre-listening is Episode 14: Principles of Quantum Mechanics, and Episode 61: Magnetism. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything
SKYSHOWTIME Mobland: Tierra de Mafiosos - 14:23 Blocco 181 - 17:18 Dexter: Resurrection - 19:16 PRIME VIDEO Impostura - 26:24 El Verano en que me Enamoré - 30:54 La Novia - 33:10 La Cuenta Atrás - 35:45 Gen V - 38:07 Upload - 40:16 APPLE TV+ El Gran Guerrero - 44:58 Sticks: Cracks del Golf - 50:52 Smoke - 54:24 Platónico T2 - 58:37 FILMIN Inspectora Ellis - 1:01:39 Virdee - 1:04:25 Boglands - 1:06:39 Contra la Ley - 1:09:35 MAX El Pacificador - 1:12:05 Viudas negras, putas y chorras - 1:16:02 Los Asesinatos de la tienda de yogur - 1:20:14 Rey y Conquistador - 1:25:34 Task - 1:29:39 DISNEY+ Blog en Serie no va a comentar series de Disney+ a causa de la cancelación permanente de ‘El Show de Jimmy Kimmel' y en protesta por el ataque a la libertad de expresión que eso supone. MOVISTAR+ Outlander: Blood of my Blood - 1:37:05 Obesidad Infantil - 1:46:10 Los Amos de la Ciudad - 1:49:06 La Caza: Irati - 1:55:10 OTRAS CADENAS Y PLATAFORMAS The Guest (BBC) - 1:57:55 Takopi - 2:01:02 El Conde de Montecristo (RTVE Play) - 2:03:00 NETFLIX Dos Tumbas - 2:06:49 Diario de una chica experta en desastres de amor - 2:12:52 Superestar - 2:16:24 Miércoles - 2:22:40 The Biggest Looser: La verdada del reality paara perder peso: 2:25:42 —------------------------------------------------------------------------------------------------ Podéis encontrarnos en redes sociales: Instagram: @fever_seriestv // @blogenseriepodcast // @monittiniseries Telegram: t.me/blogenserie Grupo de WhatsApp: https://whatsapp.com/channel/0029VaFrLzhK0IBl9rEiZT29 Youtube: https://www.youtube.com/@blogenserie4489 Substack: https://blogenserie.substack.com/ Recordad que podéis hacernos llegar vuestro cariño de varias formas: Comentarios en ivoox o en spotify. Comentarios en instagram, en las publicaciones o por privado. Suelo contestar. Puntuándonos a través de las estrellas de Apple Podcast y Spotify. Dando al corazoncito de ivoox. Invitándonos a un café en ko-fi
Fiji have sewn up a third consecutive Pacific Nations Cup win with victory over Japan in the grand final. Are they now too good for the PNC? Fijian rugby is in the best place it ever has been and they have firmly made the step from T2 nation to T1. Welcome back to the HG Rugby Podcast. The Pacific Nations Cup might not be the competition that gets the most press coverage, certainly not compared to the Six Nations or the Rugby Championship, but this year, in 2025, it was perhaps one of the most consequential championships in the world, as it decided not only who gets the glory of being the Pacific Champions, but also who gets an automatic World Cup spot in Australia. This year, Fiji took home their third consecutive crown, and once again, A.D. Jones of Japan came up short. To deep dive all of it, I'm welcoming back one of my favourite guests to the HG Rugby podcast, journalist Steve Noble. Follow me on twitter: https://x.com/HuwGriffinRugby Follow me on Facebook: https://www.facebook.com/profile.php?id=61580910041103 Follow Steve on Twitter: https://x.com/RugbyAsia247 #Fiji #Samoa #Tonga #USA #Canada #Japan #Chile #womensrugby #worldcup #pacificnationscup #fijirugby #rugbyunion Chapters 0:00 Fiji Review 10:43 Japan Review 22:30 Tonga Review 29:32 Canada Review 34:30 USA Review 43:30 Samoa Review 53:15 Women's World Cup Debate Learn more about your ad choices. Visit podcastchoices.com/adchoices
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba paket T-2 TV+NET.https://www.t-2.net/paketi/t2-tvnetFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
Seguimos con la nueva temporada y abordamos un tema delicado, una Comic Con que no está exenta de polémica pero que conforme se acerca su fecha se confirma que va a ser todo un evento. Quince días antes de que se celebre hablamos de todo lo que se puede hablar de su gestión previa y volveremos a ella una vez concluida, para valorar de manera más justa. Pero ese es solo el tema central, que luego os traemos un montón de reseñas. -Comic-Con Málaga 2025, luces y sombras (00:08:40) -Ensalada de reseñas (00:36:10) CINE: Agárralo como puedas (2025), Sorry Baby, Molt Lluny SERIES: Dan Da Dan T2, Miércoles T2, Long Story Short CÓMIC/MANGA: Tokio Babylon, Starman, Lo malo de ser bueno, Hay algo matando niños VIDEOJUEGOS: Doki Doki Panic, Hell is Us LITERATURA: Una educación mortal, El Código Pirata, Los Diablos Y recordad que regresamos cada semana y que estamos 24/7 en www.hellofriki.com y en redes. Además de nuestro grupo de Telegram A frikear!
Apple lanzó macOS Tahoe 26 con diseño Liquid Glass, Phone app propia, Spotlight más potente y traducción en vivo con Apple Intelligence Por Félix Riaño @LocutorCo Apple ya puso a disposición de todos los usuarios de Mac la actualización macOS Tahoe 26. Esta versión, anunciada en junio durante la WWDC, llega con un diseño renovado llamado Liquid Glass que cambia ventanas, botones y notificaciones. Además, mejora el buscador Spotlight para que sea más útil y hasta pueda ejecutar acciones sin abrir aplicaciones. Una novedad es la app de Teléfono, que replica la de iOS y permite recibir llamadas del iPhone en el computador, con funciones como Call Screening para filtrar números desconocidos o Hold Assist para esperar en línea automáticamente. Tahoe 26 también es la última gran actualización para los Mac con procesadores Intel que incluyen el chip de seguridad T2. ¿Qué significa eso para quienes aún usan esos equipos? Los usuarios de Intel ven cerca el final de soporte macOS Tahoe 26 introduce un rediseño total con Liquid Glass. Este estilo transparente se extiende al centro de control, la barra de menús y hasta las carpetas, que ahora pueden personalizarse con colores y emojis. Spotlight, el buscador del sistema, no solo encuentra archivos y aplicaciones, ahora también permite enviar correos o crear notas directamente, como si fuera un asistente dentro del sistema. Apple agregó la app de Teléfono que integra recientes, favoritos y buzón de voz. Así, cualquier llamada del iPhone se puede atender desde la Mac, con traducción en vivo de audio o mensajes, gracias a Apple Intelligence. Aunque la actualización trae funciones atractivas, es también la última vez que los Mac con procesadores Intel reciben un cambio mayor. Solo los modelos con chip T2 están incluidos en Tahoe 26, lo que deja claro que Apple se enfoca en Apple Silicon. Para quienes aún usan Mac antiguos, esto significa que pronto no recibirán novedades ni mejoras. El fin de soporte plantea dudas de seguridad, porque aunque todavía habrá parches pequeños, el ritmo de innovación ya no será el mismo. Esta decisión también obliga a muchos usuarios a considerar un cambio de equipo, lo que no siempre es posible por costos o compatibilidad con software profesional que aún funciona mejor en Intel. Apple plantea Tahoe 26 como la transición definitiva hacia Apple Silicon. Los Mac con procesadores M1, M2 y M3 aprovecharán todo el potencial de Apple Intelligence: traducción en llamadas, búsqueda visual en imágenes y accesos directos que se automatizan con modelos de IA en el propio dispositivo. También se abren nuevas posibilidades para desarrolladores, que pueden integrar estas funciones en sus apps. Quienes tengan equipos Intel compatibles podrán disfrutar de esta actualización, pero después de Tahoe dependerán de parches menores. Para usuarios creativos, esta es una oportunidad de decidir si continúan con sus máquinas actuales o si es hora de planear un salto a Apple Silicon. El lanzamiento de Tahoe ocurre junto con iOS 26, iPadOS 26, watchOS 26, tvOS 26 y visionOS 26. Todos comparten el mismo diseño Liquid Glass, lo que da coherencia entre dispositivos. iOS 26, por ejemplo, también trae Call Screening y traducción en llamadas, además de nuevos fondos para chats y control de spam. En iPad, la novedad más grande es un sistema de ventanas para trabajar con varias apps a la vez. Apple Watch añade puntaje de sueño y alertas de hipertensión validadas en estudios clínicos. Apple TV suma karaoke con el iPhone como micrófono, y Vision Pro recibe escenas espaciales y nuevas Personas realistas. Todo esto fortalece el ecosistema y hace que los usuarios se sientan dentro de un mismo lenguaje visual y funcional. macOS Tahoe 26 marca un cambio histórico: última gran actualización para Mac con Intel y el salto pleno a Apple Silicon. Llega con diseño Liquid Glass, mejoras en Spotlight y una app de Teléfono con traducción en vivo. ¿Ya actualizaste? Cuéntame tu experiencia y no olvides seguir el pódcast Flash Diario. Apple lanzó macOS Tahoe 26: nuevo diseño Liquid Glass, Spotlight inteligente, Phone app integrada y última gran actualización para Mac Intel. BibliografíaThe VergeApple NewsroomWashington PostNew York Times WirecutterTechCrunchPhoneArenaForbesHowToiSolveConviértete en un seguidor de este podcast: https://www.spreaker.com/podcast/flash-diario-de-el-siglo-21-es-hoy--5835407/support.
Transitions can make or break your race, and changing between sports are often where valuable seconds slip away. In this episode, we dig deep into the ins and outs of T2 with Coaches Elizabeth James and Ben Sommerville. From getting your legs ready for a run while wrapping up your ride and finding your transition spot fast to practicing the sequence of changing your gear quickly and what amenities the coaches recommend you use or skip in the transition area, Ben and Elizabeth share practical tips and real-world strategies to streamline your next race. Plus, enjoy some unforgettable stories from their own triathlon journeys. Whether you're a first-timer or a seasoned racer, this episode will help you move from biking to running like a pro.
Assistant Professor Mohammad Mirhosseini (Caltech EE/APh) explains how his group built a mechanical quantum memory that stores microwave-photon quantum states far longer than typical superconducting qubits, and why that matters for hybrid quantum architectures. The discussion covers microwave photons, phonons, optomechanics, coherence versus lifetime (T2 vs. T1), current speed bottlenecks, and implications for quantum transduction and error mechanisms. The discussion centers on a paper from Mirhosseini's paper from December of 2024 titled, “A mechanical quantum memory for microwave photons,” detailing strong coupling between a transmon and a long‑lived nanomechanical oscillator for storage and retrieval of nonclassical states.GuestMohammad Mirhosseini is an Assistant Professor of Electrical Engineering and Applied Physics at Caltech, where his group engineers hybrid superconducting–phononic–photonic systems at millikelvin temperatures for computing, communication, and sensing. He completed his PhD at the University of Rochester's Institute of Optics and was a postdoc in Oscar Painter's group at Caltech before starting his lab. His recent team effort demonstrates mechanical oscillators as compact, long‑lived quantum memories integrated with superconducting circuits.Key topicsWhat “microwave photons” are and how qubits emit/absorb single microwave photons in circuit QED analogously to atoms and optical photons.Why “memory” is missing in today's quantum processors and how a dedicated long‑lived storage element can complement fast but dissipative superconducting qubits.Optomechanics 101: mapping quantum states between electrical and mechanical degrees of freedom, with phonons as the quantized vibrational excitations.T1 vs. T2: demonstrated order‑of‑magnitude gains in lifetime (T1) and more modest current gains in coherence (T2), plus paths to mitigate dephasing.Present bottleneck: state conversion between qubit and oscillator is about 100× slower than native superconducting operations, with clear engineering avenues to speed up.Quantum transduction: leveraging the same mechanical intermediary to bridge microwave and optical domains for interconnects and networking.Two‑level system (TLS) defects: shared decoherence mechanisms across mechanical oscillators and superconducting circuits and why comparing both can illuminate materials limits.Why it mattersHybrid architectures that pair fast processors with long‑lived memories are a natural route to scaling, and mechanical oscillators offer lifetimes far exceeding conventional superconducting storage elements while remaining chip‑integrable.. Demonstrating nonclassical state storage and retrieval with strong qubit–mechanics coupling validates mechanical oscillators as practical quantum memories and sets the stage for on‑chip transduction. Overcoming current speed limits and dephasing would lower the overhead for synchronization, buffering, and possibly future fault‑tolerant protocols in superconducting platforms.Episode highlightsA clear explanation of microwave photons and how circuit QED lets qubits create and absorb them one by one.Mechanical memory concept: store quantum states as phonons in a gigahertz‑frequency nanomechanical oscillator and read them back later.Performance today: roughly 10–30× longer T1 than typical superconducting qubits with current T2 gains of a few×, alongside concrete strategies to extend T2.Speed trade‑off: present qubit–mechanics state transfer is ~100× slower than native superconducting gates, but device design and coupling improvements are underway.Roadmap: tighter coupling for in‑oscillator gates, microwave‑to‑optical conversion via the same mechanics, and probing TLS defects to inform both mechanical and superconducting coherence.
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba Najboljši paket T-2 in telefon:https://www.t-2.net/cas-je-za-vec-izberite-najboljsi-t-2-paket-telefonFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
Milt and Dave fired up the Time Machine and landed smack in September of 1991, when mullets were plentiful and Blockbuster late fees could bankrupt you. We're running down the box-office champs—from Arnold blowing stuff up in Terminator 2 to Billy Crystal roping cattle in City Slickers, with pit stops at Woody Harrelson's baby-faced cameo in Doc Hollywood and the horror sequels nobody really asked for. Along the way, we: Trade war stories about seeing these flicks in sticky-floored theaters. Act out scenes like idiots (you're welcome). Dish out Rotten Tomatoes scores and wildly unfair judgments. Wonder aloud why The Commitments still slaps and why Dead Again deserved more love. Debate whether Robin Hood: Prince of Thieves is epic or just Kevin Costner cosplaying with a bad accent. And yes—some of these movies aged like fine wine (T2), while others… let's just say they've turned to vinegar (Child's Play 3, I'm looking at you). Episode Breakdown 00:00 – Bickering & Banter 01:19 – Dave apologizes for… something. Again. 02:17 – Nostalgia bomb: our '91 movie memories 03:56 – The countdown begins 07:20 – The Commitments review 17:27 – Robin Hood: Prince of Thieves 27:44 – City Slickers 38:40 – The Doctor 45:47 – Child's Play 3 (spoiler: nope) 47:03 – Box office chatter & that weird UK crime link 51:40 – Doc Hollywood + baby Woody Harrelson 58:25 – Hot Shots! (Charlie Sheen's golden era) 01:08:10 – Terminator 2 drops the hammer 01:16:40 – Dead Again review 01:23:09 – Freddy's Dead autopsy 01:31:28 – Winner of the Week & closing thoughts It's loud, it's nostalgic, it's a little snarky—just another ride in the Top 10 Time Machine.
This week isn't about two new cameras—or even four. We've got six brand-new cameras hitting the market, most of them from major manufacturers. It looks like everyone wants to reveal their latest gear just before IBC, which means this year's show is shaping up to be an exciting one. In this special episode, we dive into all the fresh announcements: new cameras, lenses, and even some software updates. Tune in to get the full picture of what's about to be showcased at IBC! Chapters and Articles in This Episode (00:00) – Intro (01:49) - Canon EOS C50 Review & Mini-Doc: Open-Gate, Anamorphic Options, and Great Value https://www.cined.com/canon-eos-c50-review-mini-doc-open-gate-anamorphic-options-and-great-value/ (23:26) - Nikon ZR Released – First Nikon RED Camera with Internal R3D, 6K60, 4K120, 32-bit Float Audio, and More https://www.cined.com/nikon-zr-released-first-nikon-red-camera-with-internal-r3d-6k60-4k120-32-bit-float-audio-and-more/ https://www.cined.com/nikon-zr-hands-on-with-the-first-mirrorless-camera-with-red-tech/ (40:25) - RED V-RAPTOR XE Announced – Half the Frame Rates, Half the Price https://www.cined.com/red-v-raptor-xe-announced-half-the-frame-rates-half-the-price/ (43:59) - FUJIFILM GFX ETERNA 55 Full Specs & Price Released - 102MP 4:3 Large Format Cinema Camera. https://www.cined.com/fujifilm-gfx-eterna-55-full-specs-price-released-102mp-43-large-format-cinema-camera/ (57:25) - Pixboom Spark High-Speed Camera Launches – 4.6K Global Shutter, Up To 2,182 fps, and “Unlimited” RAW https://www.cined.com/pixboom-spark-high-speed-camera-launches-4-6k-global-shutter-up-to-2182-fps-and-unlimited-raw/ (01:04:19) - Apple iPhone 17 Pro Introduces ProRes RAW and Genlock for Filmmakers https://www.cined.com/apple-iphone-17-pro-introduces-prores-raw-and-genlock-for-filmmakers/ (01:09:11) - Blackmagic Camera ProDock for iPhone 17 Pro Adds HDMI, Genlock, Timecode, USB-C SSDs, 12V Power and Audio Connections https://www.cined.com/blackmagic-camera-prodock-iphone-17-pro-connections/ (01:14:29) - Pixel 10 Pro Quietly Unlocks DCG, Delivering True 12-Bit RAW Video https://www.cined.com/pixel-10-pro-quietly-unlocks-dcg-delivering-true-12-bit-raw-video/ (01:17:28) - Apple Final Cut Camera 2.0 – Open Gate, Apple Log 2 and ProRes RAW, Genlock for iPhone 17 Pro https://www.cined.com/apple-final-cut-camera-2-0-open-gate-apple-log-2-and-prores-raw-genlock-for-iphone-17-pro/ (1:19:00) - Blackmagic Camera 3.0 Update Adds Clip Syncing for Multi-Cam Shoots https://www.cined.com/blackmagic-camera-3-0-update-adds-clip-syncing-for-multi-cam-shoots/ (01:19:44) - DaVinci Resolve 20.2 Brings ProRes RAW, Better Immersive Workflows, and AI Fog Effects https://www.cined.com/davinci-resolve-20-2-brings-prores-raw-better-immersive-workflows-and-ai-fog-effects/ (01:26:19) - SIGMA Expands Full-Frame Lens Lineup With 20-200mm Zoom, 35mm F1.2 II, and 135mm F1.4 Art https://www.cined.com/sigma-expands-full-frame-lens-lineup-with-20-200mm-zoom-35mm-f1-2-ii-and-135mm-f1-4-art/ (01:30:33) - Canon RF 85mm F/1.4L VCM Released – A Compact Portrait Lens https://www.cined.com/canon-rf-85mm-f-1-4l-vcm-released-a-compact-portrait-lens/ (01:31:42) - Canon CINE-SERVO 11-55mm T2.95-3.95 Lens Released: Ultra-Wide CINE-SERVO Zoom https://www.cined.com/canon-cine-servo-11-55mm-t2-95-3-95-lens-released-ultra-wide-cine-servo-zoom/ (01:33:05) - FUJINON GF32-90mm T3.5 PZ OIS WR Lens Announced - Purpose-built for GFX ETERNA55 https://www.cined.com/fujinon-gf-32-90mm-t3-5-pz-ois-wr-lens-announced-purpose-built-for-gfx-eterna-55/ We hope you enjoyed this episode! You have feedback, comments, or suggestions? Write us at podcast@cined.com
Ataxia is a neurologic symptom that refers to incoordination of voluntary movement, typically causing gait dysfunction and imbalance. Genetic testing and counseling can be used to identify the type of ataxia and to assess the risk for unaffected family members. In this episode, Katie Grouse, MD, FAAN, speaks with Theresa A. Zesiewicz, MD, FAAN, author of the article “Ataxia” in the Continuum® August 2025 Movement Disorders issue. Dr. Grouse is a Continuum® Audio interviewer and a clinical assistant professor at the University of California San Francisco in San Francisco, California. Dr. Zesiewicz is a professor of neurology and director at the University of South Florida Ataxia Research Center, and the medical director at the University of South Florida Movement Disorders Neuromodulation Center at the University of South Florida and at the James A. Haley Veteran's Hospital in Tampa, Florida. Additional Resources Read the article: Ataxia Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Grouse: This is Dr Katie Grouse. Today I'm interviewing Dr Theresa Zesiewicz about her article on ataxia, which appears in the August 2025 Continuum issue on movement disorders. Welcome to the podcast, and please introduce yourself to our audience. Dr Zesiewicz: Well, thank you, Dr Grouse. I'm Dr Theresa Zesiewicz, otherwise known as Dr Z, and I'm happy to be here. Dr Grouse: I have to say, I really enjoyed reading your article. It was a really great refresher for myself as a general neurologist on the topic of ataxia and a really great reminder on a great framework to approach diagnosis and management. But I wanted to start off by asking what you feel is the key message that you hope our listeners will take away from reading your article. Dr Zesiewicz: Yes, so, thanks. I think one of the key messages is that there has been an explosion and renaissance of genetic testing in the past 10 years that has really revolutionized the field of ataxia and has made diagnosis easier for us, more manageable, and hopefully will lead to treatments in the future. So, I think that's a major step forward for our field in terms of genetic techniques over the last 10 years, and even over the last 30 years. There's just been so many diseases that have been identified genetically. So, I think that's a really important take-home message. The other take-home message is that the first drug to treat Friedreich's ataxia, called omaveloxolone, came about about two years ago. This was also a really landmark discovery. As you know, a lot of these ataxias are very difficult to treat. Dr Grouse: Now pivoting back to thinking about the approach to diagnosis of ataxia, how does the timeline of the onset of ataxia symptoms inform your approach? Dr Zesiewicz: The timeline is important because ataxia can be acute, subacute or chronic in nature. And the timeline is important because, if it's acute, it may mean that the ataxia took place over seconds to hours. This may mean a toxic problem or a hypoxic problem. Whereas a chronic ataxia can occur over many years, and that can inform more of a neurodegenerative or more of a genetic etiology. So, taking a very detailed history on the patient is very important. Sometimes I ask them, what is the last time you remember that you walked normal? And that can be a wedding, that can be a graduation. Just some timeline, some point, that the patient actually walked correctly before they remember having to hold onto a railing or taking extra steps to make sure that they didn't fall down, that they didn't have imbalance. That sometimes that's a good way to ask the patient when is the last time they had a problem. And they can help you to try to figure out how long these symptoms have been going on. Dr Grouse: I really appreciate that advice. I will say that I agree, it can sometimes be really hard to get patients to really think back to when they really started to notice something was different. So, I like the idea of referencing back to a big event that may be more memorable to them. Now, given that framework of, you know, thinking through the timeline, could you walk us through your approach to the evaluation of a patient who presents to your clinic with that balance difficulties once you've established that? Dr Zesiewicz: Sure. So, the first thing is to determine whether the patient truly has ataxia. So, do they have imbalance? Do they have a wide base gait? That's very important because patients come in frequently to your clinic and they'll have balance problems, but they can have knee issues or hip issues, neuropathy, something like that. And sometimes what we say to the residents and the students is, usually ataxia or cerebellar symptoms go together with other problems, like ocular problems are really common in cerebellar syndromes. Or dysmetria, pass pointing, speech disorder like dysarthria. So, not only do you need to look at the gait, but you should look at the other symptoms surrounding the gait to see if you think that the patient actually has a cerebellar syndrome. Or do they have something like a vestibular ataxia which would have more vertigo? Or do they have a sensory ataxia, which would occur if a person closes his eyes or has more ataxia when he or she is in the dark? So, you have to think about what you're looking at is the cerebellar syndrome. And then once we look to see if the patient truly has a cerebellar syndrome, then we look at the age, we look at---as you said before, the timeline. Is this acute, subacute, or chronic? And usually I think of ataxia as falling into three categories. It's either acquired, it's either hereditary, or it's neurodegenerative. It can be hereditary. And if it's not hereditary, is it acquired, or is it something like a multiple system atrophy or a parkinsonism or something like that? So, we try to put that together and start to narrow down on the diagnosis, thinking about those parameters. Dr Grouse: That's really a helpful way to think through it. And it is true, it can get very complex when patients come in with balance difficulties. There's so many things you need to think about, but that is a great way to think about it. Of course, we know that most people who come in to the Movements Disorders clinic are getting MRI scans of their brains. But I'm curious, in which cases of patients with cerebellar ataxia do you find the MRI to be particularly helpful in the diagnosis? Dr Zesiewicz: So, an MRI can be very important. Not always, but- so, something like multiple system atrophy type C where you may see a hot cross bun sign or a pontine hyperintensity on the T2-weighted image, that would be helpful. But of course, that doesn't make the diagnosis. It's something that may help you with the diagnosis. In FXTAS, which is fragile X tremor/ataxia syndrome, the patient may have the middle cerebellar peduncle sign or the symmetric hyperintensity in the middle cerebellar peduncles, which is often visible but not always. Something like Wernicke's, where you see an abnormality of the mammillary bodies. Wilson's disease, which is quite rare, T2-weighted image may show hyperintensities in the putamen in something like Wilson's disease. Those are the main MRI abnormalities, I think, with ataxia. And then we look at the cerebellum itself. I mean, that seems self-evident, but if you look at a sagittal section of the MRI and you see just a really significant atrophy of the cerebellum, that's going to help you determine whether you really have a cerebellar syndrome. Dr Grouse: That's really encouraging to hear a good message for all of us who sometimes feel like maybe we're missing something. It's good to know that information can always come up down the line to make things more clear. Your article does a great review of spinal cerebellar ataxia, but I found it interesting learning about the more recently described syndrome of SCA 27B. Would you mind telling us more about that and other really common forms of SCA that's good to keep in mind? Dr Zesiewicz: Sure. So, there are now 49 types of spinal cerebellar ataxia that have been identified. The most common are the polyglutamine repeat diseases: so, spinocerebellar ataxia type 3 or type 2, type 6, are probably the most common. One of the most recent spinocerebellar ataxias to be genetically identified and clinically identified is spinocerebellar ataxia 27B. This is caused by a GAA expansion repeat in the first intron of the fibroblast growth factor on chromosome 13. And the symptoms do include ataxia, eye problems, downbeat nystagmus, other nystagmus, vertical, and diplopia. It appears to be a more common form of adult-onset ataxia, and probably more common than was originally thought. It may account for a substantial number of ataxias, like, a substantial percentage of ataxias that we didn't know about. So, this was really a amazing discovery on SCA 27B. Dr Grouse: Now a lot of us I think feel a little anxious when we think about genetic testing for ataxia simply because there's so many forms, things are changing quickly. Do you have a rule of thumb or a kind of a framework that we can think of as we approach how we should be thinking about getting genetic testing for the subset of patients? Dr Zesiewicz: Sure. And I think that this is where age comes into play a lot. So, if you have a child who's 10, 11, or 12 who's having balance problems in the schoolyard, does not have a history of ataxia in the family, the teachers are telling you that the child is not running correctly, they're having problems with physical education, that is someone who you would think about testing for Friedreich's ataxia. A preteen or a child, that would be one thing that would be important to test. When you talk to your patient, it's important to really take a detailed family history. Not just mom or dad, but ethnicity, grandparents, etc. And sometimes, once in a while, you come up with a known spinal cerebellar ataxia. Then you can just test for that. So, if a person is from Portugal or has Portugal background and they have ataxia and the parents had ataxia, you would think of spinal cerebellar ataxia type 3. Or if they're Brazilian, or if the person is from a certain area of Cuba and mom and dad had ataxia and that person has ataxia, you would think of spinal cerebellar ataxia type 2. Or if a person has ataxia and their parent had blindness or visual problems, you may be more likely to think of spinal cerebellar ataxia type 7, for example. If they have that---either they have a known genetic cause in in the family, first degree family, or they come from an area of the world in which we can pinpoint what type we think it is---you can go ahead and get those tests. If not, you can take an ataxia comprehensive panel. Many times now, if you take the panel and the panel is negative, it will reflex to the whole exome gene sequencing, where we're finding really unusual and more rare types of ataxia, which are very interesting. Spinal cerebellar ataxia type 32, spinal cerebellar ataxia type 36, I had a spinal cerebellar ataxia type 15. So, I think you should start with the age, then the family history, then where the person is from. And then, if none of those work out, you can get a comprehensive panel, and then go on to whole exome gene sequencing. Dr Grouse: That's really, really useful. Thank you so much for breaking that down in a really simple way that a lot of us can take with us. Pivoting a little bit now back towards different types of acquired ataxias, what are some typical lab tests that you recommend for that type of workup? Dr Zesiewicz: Again, if there's no genetic history and the person does not appear to have a neurodegenerative disease, we do test for acquired ataxias. Acquired ataxias can be complex. Many times, they are in the autoimmune family. So, what we start with are just basic labs like a CBC or a CMP, but then we tried to look at some of the other abnormalities that could cause ataxia. So, celiac disease, stiff person syndrome. So, you would look at anti-glutamic acid decarboxylase antibodies, Hashimoto's---so, antithyroglobulin antibodies or antithyroperoxidase antibodies would be helpful. You know, in a case of where the patients may have an underlying neoplasm, maybe even a paraneoplastic workup, such as an anti-Hu, anti-Yo, anti-Ri. A person has breast cancer, for example, you may want to take a paraneoplastic panel. I've been getting more of the anti-autoimmune encephalitis panels in some cases, that were- that are very interesting. And then, you know, things that sometimes we forget now like the syphilis test, thyroid-stimulating test, take a B12 and folate, for example. That would be important. Those are some of the labs. We just have on our electronic chart a group of acquired labs for ataxia. If we can't find any other reason, we just go ahead and try to get those. Dr Grouse: Now, I'm curious what you think is the most challenging aspect of diagnosing a patient with cerebellar ataxia? Dr Zesiewicz: So, for those of us who see many of these patients a day, some of the hardest patients are the ones that---regardless of the workup that we do, we've narrowed it down, it's not hereditary. You know, they've been through the whole exome gene sequencing and we've done the acquired ataxia workup. It doesn't appear to be that. And then we've looked for parkinsonism and neurodegenerative diseases, and it doesn't appear to be that either; like, the alpha-synuclein will be negative. Those are the toughest patients, where we think we've done everything and we still don't have the answer. So, I've had patients in whom I've taken care of family members years and years ago, they had a presumed diagnosis, and later on I've seen their children or other family members. And with the advent of the genetic tests that we have, like whole exome gene sequencing, we have now been able to give the patient and the family a definitive diagnosis that they didn't have 25 years ago. So, I would say don't give up hope. Retesting is important, and as science continues and we get more information and we make more landmark discoveries in genetics, you may be better able to diagnose the patient. Dr Grouse: I was wondering if you had any recommendations regarding either some tips and tricks, some pearls of wisdom you can impart to us regarding the work of ataxia, or conversely, any big pitfalls that you can help us avoid? I would love to hear about it. Dr Zesiewicz: Yeah, there's no easy way to treat or diagnose ataxia patients. I've always felt that the more patients you see- and sounds easy, but the more patients you see, the better you're going to become at it, and eventually things are going to fall into place. You'll begin to see similarities in patients, etc. I think it's important not only to make sure that a person has ataxia, but again, look at the other signs and symptoms that may point to ataxia that you'll see in a cerebellar syndrome. I think it's important to do a full neuroexam. If a person has spasticity, that may point you more towards a certain type of ataxia than if a person has no reflexes, for example, that we see in Friedreich's ataxia. Some of the ocular findings are very interesting as well. It's important to know if a person has a tremor. I've seen several Wilson's disease cases in my life with ataxia. They're very important. I think a full neuroexam and also a very detailed history would be very helpful. Dr Grouse: Tell us about some promising developments in the diagnosis and management of ataxia that we should be on the lookout for. Dr Zesiewicz: The first drug for Friedreich's ataxia was FDA-approved two years ago, which was an NRF2 activator, which was extremely exciting and promising. There are also several medications that are now in front of the FDA that may also be very promising and have gone through long clinical trials. There's a medication that's related to riluzole, which is a medication used for amyotrophic lateral sclerosis, that has been through about seven years of testing. That is before the FDA as well for spinal cerebellar ataxia. Friedreich's ataxia has now completed the first cardiac gene therapy program with AAV vectors, which- we're waiting for full results, but that's a cardiac test. But I would assume that in the future, neurological gene therapy is not far behind if we've already done cardiac gene therapy and Friedreich's ataxia. So, you know, some of these AAV vector-based genetic therapies may be very helpful, as well as ASO, antisense oligonucleotides, for example. And I think in the future, other things to think about are the CRISPR/Cas9 technology for potential treatment of ataxia. It is a very exciting time, and some major promising therapies have been realized in the past 2 to 3 years. Dr Grouse: Well, that's really exciting, and we'll all look forward to seeing these becoming more clinically applicable in the future. So, thank you so much for coming to talk with us today. Dr Zesiewicz: Thank you. Dr Grouse: Again, today I've been interviewing Dr Theresa Zesiewicz about her article on ataxia, which appears in the August 2025 Continuum issue on movement disorders. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.
In this episode, T2 consultants Scott Morrison and James Cooper discuss the topic of meetings. The conversation focuses on effective meetings, when they are necessary, and what to do within them to make them productive.Scott and James break down and describe six different types of meetings:Information Exchange Meeting: The purpose is to share critical information, like a press conference, with a clear agenda.Status Update Meeting: This meeting is a quick "pit stop" to keep a project on track with a structured format, focusing on what has been done, what will be done, and any potential blockers. The focus is on quick updates, not a person's life story.Team Build Meeting: This type of meeting is for strengthening relationships, building trust, and fostering human connection and collaboration within a team. These sessions can include icebreakers and informal discussions to create a safe space for communication.Blue Sky Session: These are creative, mind-mapping sessions where there are no judgments or constraints, and no ideas are considered "bad". The goal is to think differently and challenge the norm.Big Decision Meeting: The purpose of this meeting is to make significant, high-impact choices. It involves reviewing options and analysing data that has been provided beforehand. The speakers use a jury deliberation as an analogy for this type of meeting.Problem Solver Meeting: This meeting is for a team to collectively identify the root cause of an issue and develop solutions. The focus is on getting to the root cause, analysing the issue, and collaboratively designing a solution.This episode also provides tips for effective meetings, including:Creating and sharing a clear agenda and expectations.Inviting only the necessary people.Designating a facilitator to keep the conversation on track.Establishing ground rules, such as no phones or distractions.Practicing good time management.Concluding the meeting with clear next steps, assigning ownership, actions, and timeframes (OAT).Join our FREE webinar "Plan, Prepare, and Persuade: Leading Change That Lasts" on September 17th, with our COO and Head of consultancy and podcast Co-Host Tracy Roberts!Click here to sign up - https://trans2performance.com/t2events/plan-prepare-persuade Follow us on social media - Instagram - ttps://www.instagram.com/peopleperformancepodcast/LinkedIn - https://www.linkedin.com/company/t2-thepeopleperformancepeopleTikTok - https://www.tiktok.com/@peopleperformancepod
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba Najboljši paket T-2 in telefon:https://www.t-2.net/cas-je-za-vec-izberite-najboljsi-t-2-paket-telefonFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
AUGGIE SMITH AKA THE T-1000 IN STUDIO!! With Peacemaker Season 2 Episode 3 now out, James Gunn Man Of Tomorrow Announced, Greg Alba sits down with legendary actor Robert Patrick (James Cameron's Terminator 2: Judgment Day) for a candid, career-spanning conversation. Visit https://huel.com/rejects to get 15% off your order We get into the many T2 restorations (theatrical vs 4K/3D re-release, what version he recommends, screening it at Cameron's studio during Avatar work), theatrical culture today, and how Patrick's craft evolved from the Roger Corman days through The Sopranos (David Chase), The X-Files (Agent John Doggett), Cop Land, Walk the Line (James Mangold), and beyond. He opens up about fatherhood, faith, and building flawed men with humanity (from Peacemaker's Auggie Smith in S1 to the very different Auggie of Peacemaker Season 2), plus on-set stories of John Cena's insane work ethic, ad-lib prep, and learning instruments. We also touch on early movie memories with his dad (2001: A Space Odyssey, Sean Connery's James Bond), acting process (prep vs spontaneity, Benedict Cumberbatch's Hamlet), working alongside Sylvester Stallone (Tulsa King), Harrison Ford, and Joaquin Phoenix, and why storytelling is the ultimate empathy machine. If you love Terminator 2, DC's Peacemaker, prestige TV, and acting deep dives, this one's for you. Intense Suspense by Audionautix is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... Support The Channel By Getting Some REEL REJECTS Apparel! https://www.rejectnationshop.com/ Follow Us On Socials: Instagram: https://www.instagram.com/reelrejects/ Tik-Tok: https://www.tiktok.com/@reelrejects?lang=en Twitter: https://x.com/reelrejects Facebook: https://www.facebook.com/TheReelRejects/ Music Used In Ad: Hat the Jazz by Twin Musicom is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Happy Alley by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... POWERED BY @GFUEL Visit https://gfuel.ly/3wD5Ygo and use code REJECTNATION for 20% off select tubs!! Head Editor: https://www.instagram.com/praperhq/?hl=en Co-Editor: Greg Alba Co-Editor: John Humphrey Music In Video: Airport Lounge - Disco Ultralounge by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Ask Us A QUESTION On CAMEO: https://www.cameo.com/thereelrejects Follow TheReelRejects On FACEBOOK, TWITTER, & INSTAGRAM: FB: https://www.facebook.com/TheReelRejects/ INSTAGRAM: https://www.instagram.com/reelrejects/ TWITTER: https://twitter.com/thereelrejects Follow GREG ON INSTAGRAM & TWITTER: INSTAGRAM: https://www.instagram.com/thegregalba/ TWITTER: https://twitter.com/thegregalba Learn more about your ad choices. Visit megaphone.fm/adchoices
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba T2 Ščit:https://www.t-2.net/t-2-scit-za-varnost-na-internetuFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
The incredible world of weight loss supplements... let's dive in and learn how they can be game-changers for those of us navigating hypothyroidism or Hashimoto's. This episode, I'm zooming in on safe, effective options that won't leave your heart racing or cause you more harm than good. I'm talking about the unsung heroes like T2 (3,5-diiodo-l-thyronine) and L-tyrosine, which can boost your metabolism and even help with fat burning while keeping your muscle mass intact. These alternatives set themselves apart from the risky, old-school stimulants like ephedra and caffeine, making your weight loss journey not just manageable but healthier. You see, weight loss with thyroid issues is a whole different ballgame. I'm spilling all the details on supplements like coleus forskohlii and Guggul, which not only support thyroid function but also enhance fat metabolism and offer other fantastic benefits—think better insulin resistance, lipid profiles, and even some mood-boosting effects. And yes, these finds are already star players in my products, “Thyroid Fixxr” and “Metabolism Fixxr,” designed to help you unlock that superior fat-burning potential. Listen in and let's unravel the magic behind these supplements and how they might just be the missing piece in your wellness toolkit. Head to my store and grab T2, L-tyrosine and Coleus Forskohlii in Thyroid Fixxr Additional T2 Podcast Episodes: Episode 338: All about T2: 3,5 Diiodo l Thyronine Episode 245: More Energy, Burning Body Fat and Rocking Mitochondria with T2 Shop ALL of Dr. Amie's Fixxr® Supplements: betterlifedoctor.com LET'S GET YOUR LIFE BACK...Connect with Dr. Amie Hornaman Book a free application call: https://dramiehornaman.com/pages/book-a-call FREE DOWNLOADS… What Are the Optimal Lab Ranges? What Steps Can I Take? Don't know where to start...don't know which labs are useful? And what to do when you get your results? “How To” Guide For Supplements Here's your Fixxr® supplement timeline and guide. Fix Your Thyroid and Adrenals To Fix Your Life Check your symptoms of hypothyroidism and know OPTIMAL thyroid lab values. Learn why you are being told you're “NORMAL” by your doctor. Can Supplements Help with Hypothyroidism? Grab this thorough guide to help you select the most advantageous supplements that will best suit your health circumstances. RATE, REVIEW AND FOLLOW ON APPLE PODCASTS Show your love for Amie and The Thyroid Fixer Podcast! If you're enjoying our journey together, I'd be thrilled if you could take a moment to rate and review the show on Apple Podcasts. Your support helps me reach and help more people just like you, guiding them towards their optimal selves! Just click HERE, scroll all the way down, give us those 5 stars, and share what you enjoy about my episodes in a review. Haven't subscribed yet? Make sure to follow The Thyroid Fixer Podcast to catch all the new episodes that come out every week. Follow HERE and never miss out on a moment of the journey! CONNECT WITH ME ON SOCIAL MEDIA: Join my exclusive Facebook Group, Dr. Amie…The Thyroid Fixer®...Love Your Mirror, for a Community of HOPE and Support in your thyroid journey. https://www.facebook.com/groups/dramie/ Like me on Facebook: Amie Hornaman Nutrition and Functional Medicine Subscribe on Youtube: Dr. Amie Hornaman Follow me on Instagram: @dramiehornaman
Episode 289: Adrian is joined again by our head of New Product Development, Paul Adams, to explore the complexity of plastic injection mold tooling and what it takes to go from tooling design to mass production of plastic parts. They explore the full journey, from DFM and tool design through trial runs (T0, T1, T2) to final sign-off and mass production. Along the way, they highlight common pitfalls, golden samples, and why rushing into production can be a costly mistake. You'll love this episode if you're developing plastic products, as it will help you to avoid surprises and manage expectations in the new product introduction (NPI) process. Episode Sections: (00:00:03) Introduction to episode 289 (00:00:13) Adrian welcomes back Paul Adams (00:00:35) Today's topic: plastic injection mold tooling and its complexity (00:01:11) From DFM to mass production – the journey explained (00:02:01) Why tooling is expensive and misunderstood (00:02:48) The role of DFM (Design for Manufacturing) in tooling (00:05:13) Customer involvement and asking the right questions (00:05:19) Tooling design: bolster set vs. core and cavity (00:06:21) Material procurement and standard vs. custom components (00:09:01) Machining the tool: CNC, EDM, wire cutting, polishing (00:11:12) Metal safe condition and first fitting (00:11:59) The T0 trial run explained (00:13:42) First look at molded parts and making big adjustments (00:15:09) The T1 trial run with virgin polymer (00:15:57) Inspection reports and customer sign-off (00:18:00) Surface texturing between T1 and T2 (00:18:14) T2 trial – final tuning and sign-off preparation (00:19:02) Phase gates link: tooling to mass production (00:20:19) Golden samples and color consistency checks (00:22:02) Why being on the ground in China helps with sign-off (00:23:23) Limit samples and customer approval process (00:23:55) The importance of T0–T2 for expectation management (00:24:58) Why not to rush into mass production (00:25:02) Links to prototypes and phase gate methodology (00:26:05) Don't sign off tooling until everything is consistent (00:26:59) Moving into mass production and ongoing monitoring (00:28:28) Tool lifespan and long-term considerations (00:28:48) Wrapping up: intricacies of tooling complexity (00:29:16) Sofeast NPI guide and related video resources (00:30:16) Looking ahead: polymers and material selection (00:30:45) Closing remarks and call to action Related content... How We Work With You On New Product Development & Manufacturing Projects - Agilian NPI Process Tooling Management for Plastic Injection Molds in China 7 Key NPI Tasks Before Production The Conundrum of Investing in Tooling Before a Final Prototype Inside the Tooling: Common Plastic Injection Mold Components Explained Understanding Plastic Injection Mold Tooling Complexity, from DFM to T1, When Manufacturing in China (Video) Get in touch with us Connect with us on LinkedIn Contact us via Sofeast's contact page Subscribe to our YouTube channel Prefer Facebook? Check us out on FB
Ce jeudi 28 août, le dernier baromètre d'OpinionWay concernant le moral des patrons, le chantier des retraites, le bilan de l'emploi au T2 ainsi que les conséquences de la vie politique actuelle sur les industries, ont été abordés par Sophie Sidos-Vicat, présidente des CCEF et vice-présidente de la holding du groupe Vicat, Ludovic Desautez, directeur délégué de La Tribune, Olivier Redoulès, directeur des études de Rexecode, et Alexandra Roulet, professeur à l'Insead, membre du Cercle des Économistes, dans l'émission Les Experts, présentée par Raphaël Legendre sur BFM Business. Retrouvez l'émission du lundi au vendredi et réécoutez la en podcast.
Marvel Comics' Terminator 2: Time Bomb 00:01:10Robocop #11 (1990) by Skolnick/Rupinski/2xTrimpe 00:06:11Dark Horse Presents #138 by Grant/Frank Teran 00:15:36The Terminator Special #1 (1998) by Grant/Guy Davis 00:25:38The Terminator #1 (1998) written by Alan Grant 00:41:37The Terminator #2 (1998) drawn by Steve Pugh 00:54:51The Terminator #3 (1998) 01:08:46The Terminator #4 (1998) 01:20:42The Terminator: Rewired 01:30:37Metallic Mayhem 01:33:28episode art galleryblog postComic Books, Dark Horse Comics, Dark Horse Presents, Marvel Comics, Robocop, Robocop Podcast, John Connor, Sarah Connor, The Terminator (1984), Terminator 2, Terminator 2: Judgment Day, T2, T2: Judgment Day, Terminator NOW, Terminator Podcast
Nubs será lo más adorable en el show, pero la versión adulta de su especie… sin comentarios. Entre las andadas de un puba adulto y una misión con cazarrecompensas, los jóvenes Jedi no pierden la oportunidad de aprender!Discutimos el 17mo episodio, T2, de Aventuras de Jóvenes Jedi.
In this episode of the Leader Lounge, Martin discusses optimal performance and its relevance for teams and organisations. The three distinct performance models:Peak Performance ⛰️: This model involves meticulous planning to achieve a desired outcome at a specific point in time. Optimal Performance
Welcome to “Onward! A Rose City Podcast”; a place for all your Portland Thorns, Portland Timbers, 107IST, Timbers Army, & Rose City Riveters news, along with stories of our club and culture's history plus a look into the future of soccer support in Portland, Oregon. ON THIS EPISODE! PTFC Chat: Olivia Moultrie ties teen goals record, Suman (Timbers) and Nuñez (T2) called up Legends Pre Funks and more! LINKS! Project Play initiative as.pn/PDXSportsSurvey Candlelighters Oregon Riveters Painting Featured Partner: Pacific NW Acupuncture and Herbal Clinic Supporting Trans Rights Donation Drives Ticket Exchange Facebook - Discord Have a ticket to donate? Send it to ticketdonation@107ist.org 107ist.org
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba Najboljši paket T-2 in telefon:https://www.t-2.net/cas-je-za-vec-izberite-najboljsi-t-2-paket-telefonFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
This episode is a thyroid deep dive — a jam-packed conversation with Dr. Gary E. Foresman, MD of MiddlePathMedicine.com. We tackle the biggest myths, mistakes, and misunderstandings in thyroid treatment today. Here's what we cover: The FDA Ban on Natural Desiccated Thyroid (NDT): What it really means for patients. Medication Before Labs: Why you should never take T4/T3 or T3-only meds before a thyroid test. Dosing Myths Debunked: Why no practitioner should put an arbitrary limit on T4 or T3 dosing. Beyond T4 & T3: Do T1, T2, and calcitonin in NDT actually matter? Are T2 supplements worthwhile? Failed Research: How flawed medical studies have left thyroid patients in the dust. The TSH Suppression Myth: Why suppressed TSH on T4/T3 combos or T3-only therapy is NOT dangerous, doesn't cause arrhythmias or osteoporosis, and why outdated T4-only protocols from 30 years ago created decades of false fear. Reverse T3: Why this is a critical — and often ignored — test. Blood Sugar & Thyroid Hormones: How food satiety and glucose fluctuations can masquerade as thyroid issues (like tachycardia), and why it's not always your thyroid to blame. If you've ever been confused, dismissed, or gaslit about your thyroid health, this episode will give you the clarity (and firepower) you need! Visit MiddlePathMedicine.com to learn more about Dr. Foresman. FREEBIES: Free Thyroid Guide + Video Series: https://www.elleruss.com/thyroid-guide Free Confidence eBook & Workbook: https://www.elleruss.com/7secrets Elle's newsletter: https://www.elleruss.com/newletter #theellerussshow
Send me a text! I'd LOVE to hear your feedback on this episode!This is a 2-part podcast all about the thyroid. Part 1, I interview Dr. Amie. Part 2 begins around 1 hr 10 mins, where Dr. Amie interviews me.Important links! Find & get in touch with Dr. Amie Hornaman here: https://betterlifedoctor.com/ Follow The Thyroid Fixer Podcast here (Apple link but you can find it anywhere you listen to podcasts: https://podcasts.apple.com/ca/podcast/the-thyroid-fixer/id1529800263 I am a writer as well as a holistic nutritionist and podcast host. Join my Substack to read unique perspectives on our wellness - body, mind, spirit and soul: https://sandykruse.substack.com/publish/home?utm_source=substack Grab my Essential Thyroid Guide (this is a simplified guide and not a clinical book): US: https://www.amazon.com/dp/B0CW4X3WJD Canada: https://www.amazon.ca/dp/B0CW4X3WJDThyroid health is crucially important yet often misunderstood and poorly treated in conventional medicine, leaving millions suffering with symptoms while being told they're "normal." • The thyroid is the "master gland" controlling metabolism, energy, brain function, heart rate, digestion, and emotional well-being • Conventional medicine considers TSH up to 4.5 "normal" while functional medicine seeks levels below 2.0 for optimal function • Only about 2% of thyroid patients do well on T4-only medications like Synthroid; 98% need combination therapy with T3 • Thyroidectomy patients especially need T3 supplementation since the thyroid gland is a primary site for T4 to T3 conversion • Key nutrients for thyroid health include selenium, magnesium, and iodine (which helps protect against environmental toxins) • Thyroid health closely connects with hormonal balance, particularly estrogen during perimenopause and menopause • T2, an often-overlooked thyroid hormone, can benefit metabolism and fat burning without suppressing natural thyroid function • Personalized treatment must address medication, nutrition, supplements, lifestyle factors, and mindset • "Progress is not linear" - even optimized patients need adjustments as their bodies change • Daily practices like time in nature, journaling, and energetic clearing can support thyroid healing alongside medicalSupport the showPlease rate & review my podcast with a few kind words on Apple or Spotify. Subscribe wherever you listen, share this episode with a friend, and follow me below. This truly gives back & helps me keep bringing amazing guests & topics every week.Instagram: https://www.instagram.com/sandyknutrition/Facebook Page: https://www.facebook.com/sandyknutritionTikTok: https://www.tiktok.com/@sandyknutritionYouTube: https://www.youtube.com/channel/UCIh48ov-SgbSUXsVeLL2qAgRumble: https://rumble.com/c/c-5461001Linkedin: https://www.linkedin.com/in/sandyknutrition/Substack: https://sandykruse.substack.com/Podcast Website: https://sandykruse.ca
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba T2 Ščit:https://www.t-2.net/t-2-scit-za-varnost-na-internetuFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
13일 오전 시드니 공항 국내선 T2 터미널에서 한 남성이 체포되는 과정에서 경찰 총기가 발사되는 사건이 발생했습니다. 다행히 부상자는 없었으며, 사건 직후 설정된 봉쇄 조치는 해제돼 공항은 정상 운항되고 있습니다.
In this episode, we talk with Dr. Christina Shenvi about ARIA, a finding associated with an early stage Alzheimer's infusion that can impact stroke and VTE care. The MRI of choice per neuroradiology are the T2 weighted and flare images seen on most routine head MRIs. The gradient recall echo are best for bleed and microhemorrhage. These are all part of a routine MRI. I would note in the order that you are looking for ARIA. Supported by Eli Lilly and Company
Editor of Boss Sally Patten sits down with Christelle Young, the managing director of T2 in Australia, to talk about the importance of being honest with staff, what she learnt from a 10-day silence retreat and why matcha tea is taking the world by storm. This podcast is sponsored by PGIMSee omnystudio.com/listener for privacy information.
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba Najboljši paket T-2 in telefon:https://www.t-2.net/cas-je-za-vec-izberite-najboljsi-t-2-paket-telefonFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
M3GAN 2.0 (2025)Directed By: Gerard JohnstoneStarring: Allison Williams, Violet McGraw, Amie Donald, That Guy from Flight of the ConchordsWe talked about the original M3GAN back in 2023, and to both of our surprise, we generally liked it. This time around, M3GAN is back, and it's a bit of a tonal shift, to say the least. M3GAN has a T2 moment and has to deal with a new foe. IMDB.com has this to say about M3GAN 2.0: "Two years after M3GAN's rampage, her creator, Gemma, resorts to resurrecting her infamous creation in order to take down Amelia, the military-grade weapon who was built by a defense contractor who stole M3GAN's underlying tech."We Also Talked About:Mickey 17 (Amazon)48 Hours (YouTube)The Luckiest Man in America (Amazon)Big Bucks: The Press Your Luck Scandal (Internet Archive)Robocop 2014 (Tubi)Season 2 of Quarterback (Netflix)The Clubhouse (Netflix)The Comeback (Netflix)Like what you hear here? We're on the youtubes now with our entire new back catalog and some upcoming exclusive content available at https://youtube.com/@deweypodmonster(Some of the above links are affiliate links, if you purchase through these affiliate links we do get a small kickback, and it's the best way to support this show!).Rate and Review us on the podcast platform of your choice!As always, remember, you can always find the latest goings on at our website https://Crap.TownCheck out our fellow podcast network members at https://Yourunpodcast.com
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba T2 Ščit:https://www.t-2.net/t-2-scit-za-varnost-na-internetuFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
Send us a textSPECIAL NOTE: SEASON 15 OF THE GOOD, THE POD AND THE UGLY CELEBRATES THE USE OF THE PRACTICAL AND DIGITAL EFFECT KNOWN AS THE SQUIB. IRL GUN VIOLENCE IS INTOLERABLE AND RENOUNCED BUT... CINEMATIC VIOLENCE WILL BE CELEBRATED IN A WAY WILL DISTURB SOME LISTENERS. This week TGTPTU guns down the second half of our Lance Henriksen double feature with an episode recorded in the past and sent to the listener in the future as a digital file encoding the three core hosts' discussion of writer Harlan Ellison's (please, no more legal action, ATTN: Ellison's Estate) sci-fi/80's action/quasi-horror flick THE TERMINATOR (1984). Director James Cameron (and co-writer Gale Anne Heard) broke onto the cinema scene with this low-/mid-budget, high octane film and its titular, iconic creation. Arnold Schwarzenegger plays the killer robot (technically an android but called a cyborg) Terminator sent from the future to eliminate Linda Hamilton's Sarah Connor but followed by scrappy future soldier Kyle Reese, played by Michael Biehn, and you know the deal having seen T2 (1991); this first film is when Connor gets preggers and has awesome 80's style and learns of the future badass she must, and does, become. Future fellow Cameron android player Lance Henriksen plays a cop, who may or may not die in the film, when Schwarzenegger's T-800 delivers on his iconic promise to the precinct's desk officer that he will return. (Schwarzenegger, as we learn this episode, did not want to deliver Cameron's line as written as the English word “I'll” was difficult for the bodybuilding immigrant.) The hosts this week (no Jack, no special guest Shannon) speculate on Cameron's CB sexy talk when he was a truck driver, discover where Jack got his fashion sense, and express awe as how stripped down and fast-paced the story is. Ken fondly remembers the short-lived TV series Manimal (https://en.wikipedia.org/wiki/Manimal), Ryan reveals the film to secretly be an 80's slasher, and Thomas, bummed, reacts with atemporal microaggression by introducing earlier into the pod the concept of Roko's basilisk (https://en.wikipedia.org/wiki/Roko%27s_basilisk but don't click!). A least one Cameron shows up while a confused former prime minister of England makes a brief off-mic appearance. Harlan Ellison also enters the chat, and the listener owes us $1. Hasta la vista, absent special guest Shannon Connor. May your mission down Mexico way to find and protect Chaplain Amy be met with success.THEME SONG BY: WEIRD A.I.Email: thegoodthepodandtheugly@gmail.comFacebook: https://m.facebook.com/TGTPTUInstagram: https://instagram.com/thegoodthepodandtheugly?igshid=um92md09kjg0Bluesky: @goodpodugly.bsky.socialYouTube: https://www.youtube.com/channel/UC6mI2plrgJu-TB95bbJCW-gLetterboxd (follow us!):Podcast: goodpoduglyKen: Ken KoralRyan: Ryan Tobias
Episode 307 is stacked with chaos. We welcome in new guest host Andy and immediately derail with Florida Man impersonations, emotional dad tips, wild 20s advice, and VHS home video nostalgia (complete with broom choreography). Then comes the bracket — action movie heroes go head-to-head and the debate nearly ends the show. Spoiler: Jason loses his mind over T2. Also inside: ⚡️$375 rent war stories ⚡️Why documenting grandma is crucial ⚡️Hookah flashbacks ⚡️Kevin's actually good life advice (?!) Florida Man, fake prosecutors, and a lot of yelling. Let's ride.
Tyler, 16, was diagnosed with T1D through TrialNet after testing positive—his dad has T1D, his mom T2. Three years in, he's navigating diabetes with a family who gets it. Go tubeless with Omnipod 5 or Omnipod DASH * Dexcom G7 CONTOUR NextGen smart meter and CONTOUR DIABETES app Get your supplies from US MED or call 888-721-1514 Tandem Mobi twiist AID System Free Juicebox Community (non Facebook) Eversense CGM Medtronic Diabetes Drink AG1.com/Juicebox Touched By Type 1 Take the T1DExchange survey Use code JUICEBOX to save 40% at Cozy Earth Apple Podcasts> Subscribe to the podcast today! The podcast is available on Spotify, Google Play, iHeartRadio, Radio Public, Amazon Music and all Android devices The Juicebox Podcast is a free show, but if you'd like to support the podcast directly, you can make a gift here or buy me a coffee. Thank you! * The Pod has an IP28 rating for up to 25 feet for 60 minutes. The PDM is not waterproof. Among all paid Omnipod 5 G6G7 Pods Commercial and Medicare claims in 2024. Actual co-pay amount depends on patient's health plan and coverage, they may be higher or lower than the advertised amount. Source IQVIA OPC Library. Disclaimer - Nothing you hear on the Juicebox Podcast or read on Arden's Day is intended as medical advice. You should always consult a physician before making changes to your health plan. If the podcast has helped you to live better with type 1 please tell someone else how to find it!
Welcome to “Onward! A Rose City Podcast”; a place for all your Portland Thorns, Portland Timbers, 107IST, Timbers Army, & Rose City Riveters news, along with stories of our club and culture's history plus a look into the future of soccer support in Portland, Oregon. ON THIS EPISODE! PTFC Chat: Christine Sinclair to the Thorns Hall of Fame and Timbers Army Historic tifo Help needed for Legends Away viewings Raffle for Thorns field seats Seattle Reign match T2 in Eugene and more! LINKS! Nike pass info (Membership required) - Adidas - Columbia Legends volunteer signup (you need the 107IST membership email for this) Portland Community Football Club Gol Featured Partner: Henderson Taylor Law Firm Thorn's Field Seats raffle - NWSLPA Emergency Fund T2 in Eugene Supporting Trans Rights Donation Drives Ticket Exchange Facebook - Discord Have a ticket to donate? Send it to ticketdonation@107ist.org 107ist.org
Naš najbolj prijazen pokrovitelj T2 in njihova super ponudba Najboljši paket T-2 in telefon:https://www.t-2.net/cas-je-za-vec-izberite-najboljsi-t-2-paket-telefonFejmrč na https://www.fejmici.si/Vaše težave: podcast.fejmici@gmail.comPoljubna enkratna donacija na: https://tinyurl.com/y2uyljhmMesečna finančna podpora možna na:3€ - https://tinyurl.com/yxrkqgbc5€ - https://tinyurl.com/y63643l58€ - https://tinyurl.com/y62ywkmtMotitelji:- Gašper Berganthttps://www.gasperbergant.si https://www.instagram.com/gasper.bergant/ - Žan Papičhttps://www.zanpapic.si https://www.instagram.com/zanpapi/ Produkcija: Warehouse Collectivehttps://www.warehousecollective.siGrafična podoba: Artexhttps://www.facebook.com/artextisk
Send us a textIn this episode, we dive headfirst into Terminator 2: Judgment Day—James Cameron's groundbreaking sci-fi sequel that redefined the action genre. We unpack the film's game-changing visual effects, Arnold Schwarzenegger's evolution from villain to hero, Linda Hamilton's legendary turn as a hardened Sarah Connor, and the relentless menace of Robert Patrick's T-1000. From the philosophical undertones about AI and fate to the adrenaline-pumping set pieces that still hold up decades later, we explore why T2 remains a towering achievement in both science fiction and cinema. Buckle up—it's time to say “Hasta la vista, baby” to boring film talk.Support the showBrowse the 33/24 Archives: Check out the backroom! Follow us: Instagram Facebook Watch us on YouTube!
In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the July 2025 Emergency Medicine Practice article, Emergency Department Management of Status Epilepticus in Pediatric PatientsIntroductionWelcome and brief overview of the episodePromotion of EB Medicine's $1 for 7-day trial offerWhy Pediatric Status Epilepticus MattersSeizures make up ~1% of ED visits and ~3% of EMS callsHigh-risk and high-stakes condition requiring rapid actionStatus epilepticus now defined as ≥5 minutes of seizure activityILAE's T1 and T2 timelines help define when to treat and when damage beginsCommon CausesTop contributors:Fever/infectionStructural CNS abnormalitiesToxic ingestionsGenetic/metabolic disordersAdditional factors by age:Infants: febrile seizures, chromosomal issues, traumaSchool-age: autoimmune disordersAdolescents: eclampsia, hypertension, functional disordersAlways consider non-accidental traumaPrehospital CareIM midazolam is effective and recommended (RAMPART trial)Other options: intranasal, rectal, or IV benzodiazepinesEarly benzodiazepine administration improves outcomesImportance of airway support, glucose check, and EMS flexibilityParent-administered home meds (e.g. rectal diazepam) can be helpfulED Evaluation and Initial ManagementPrioritize ABCs: Airway, Breathing, Circulation, ConsciousnessUse end-tidal CO₂ to monitor ventilation if availablePoint-of-care glucose is essentialLabs: CMP, Mg, Phos, lactate, drug levels, pregnancy test (when indicated)Imaging: Head CT if concern for trauma, shunt malfunction, or focal signsCase examples highlight pitfalls and diagnostic delaysFirst-Line TreatmentBenzodiazepines remain the cornerstoneLorazepam preferred IV agent (0.1 mg/kg)Midazolam preferred if no IV access (IN, IM, or IO)Diazepam is also effective, especially rectallyBe mindful of respiratory depression and the need for airway controlSecond- and Third-Line TherapiesBased on ESETT trial:Levetiracetam, fosphenytoin, and valproate have similar efficacyLevetiracetam favored for safety and ease of useFosphenytoin may be avoided in trauma or toxicityValproate not recommended in mitochondrial diseasePhenobarbital reserved for refractory cases onlyRefractory Status EpilepticusDefinition: persistent seizures despite first- and second-line agentsRequires sedation and likely intubationInfusion options:Midazolam (preferred for flexibility)Propofol (short-term use only due to risk of infusion syndrome)Pentobarbital (rare, ICU-level care)Need for continuous EEG to assess seizure activitySpecial ScenariosNeonates:Watch for subtle signs (lip smacking, bicycling, tongue thrusting)Broad differential includes asphyxia, infection, metabolic errorsFebrile Status Epilepticus:Higher risk of CNS infections, especially if unvaccinatedConsider lumbar puncture if indicatedElectrolyte/Metabolic Triggers:Treat hypoglycemia, hyponatremia, and hypocalcemia directlyUse 3% saline or dextrose as appropriateDisposition and Discharge ConsiderationsMany children will require ICU-level careSome known epilepsy patients may go home if back to baselineEnsure rescue medications are up to date (rectal/intranasal benzos)Consider “clonazepam bridge” for short-term seizure preventionCollaborate with neurology for medication adjustment and follow-upFinal ThoughtsKeep treatment tables and dosing references accessibleEarly, aggressive treatment can prevent long-term harmEpisode closes with gratitude to article authors and a reminder to visit EBMedicine.netEmergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net
The Smylie Show is on the road this week! Smylie Kaufman joins from the airport after a fun week in Tahoe, with Charlie Hulme on a quick trip to Ponte Vedra Beach. SK and CH begin the show recapping Chris Gotterup's breakthrough win at the Scottish Open, and whether he can complement his skill driving the ball with more complete performances like what we saw in North Berwick to take his game to the next level. After a near miss and a T2 in Scotland, Smylie and Charlie discuss a more relaxed looking Rory McIlroy, and where that positions him heading into a home game at Royal Portrush. Brandel Chamblee then joins Smylie to close the episode with a wide-ranging first look at the Open Championship, both previewing the 153rd edition and discussing whether some historic anchor sites like the Old Course can stand up to the increasing impact of technology on the game. Brandel closes with some analysis and predictions on who could emerge victorious at Portrush. CHAPTERS: 00:00 Introduction and Highlights from Tahoe 05:45 Chris Gotterup's Breakthrough Win 08:23 Rory McIlroy's Performance and Mental Game 11:22 The Evolution of Golf and Player Profiles 13:53 Bifurcation of Golf Rules and Equipment 16:54 The Role of Data in Golf Analysis 24:30 Brandel Chamblee joins the show 26:30 Bifurcation 40:24 The Intersection of Data and Storytelling in Golf TV 43:07 The Challenge of Analyzing Tiger Woods 47:39 The Impact of Tiger Woods on Golf's Financial Landscape 48:01 The Risks of Swing Changes: A Look at Current Players 52:19 The Role of Teaching in Golf 01:02:28 Scottie Scheffler 01:10:00 Rory McIlroy 01:14:56 Open Championship Predictions Big thanks to AHEAD for their support! Check them out here: https://www.ahead.com/ Enter the 2025 Dream Ireland Golf Getaway Sweepstakes by ShipSticks: https://www.shipsticks.com/sweeps/ireland-dreamgolfgetaway Use promo code SMYLIE or this link for 20% off: https://www.shipsticks.com/?utm_source=smylie&utm_medium=podcast&utm_campaign=ss_acq_pod_0_smylie2025
The Real Fans help you build a playlist with 12 awesome songs from summer movies over the years. Find more Real Fans 4 Real Movies on the internet: Web | Twitter | Facebook | Instagram Rate, review, & subscribe to the RF4RM Podcast on: Apple Podcasts | Google Play | Stitcher | TuneIn Your feedback is appreciated. Send emails to podcast@rf4rm.com
There's a spy aboard Defiant and everybody's got an excuse to act weird! And we see one of Andy's favorite complaints about Odo be proven right - he should be T2-ing and Mr. Fantastic-ing all over the place![Episode discussion begins around 1:06]
Today we take a look at the inaugural Rockford 70.3. We get into the course, race strategies, and how to handle what looks to be a hot day. We talk about the city, wetsuit or not, river flow and a pre-race HR test. We also get into how to stay as cool as possible all day with tips for pre-race, T1, the bike, T2 and the run. This will be a game of being smart and patient and we'll give you thoughts on how to do just that. Topics: Rockford Downtown - Mike's old stomping grounds Will this race jumpstart the city? Dealing with the heat Wetsuit or not? Why it's too late for heat prep Don't drain your body this week Stay out of the heat River flow Pre-race HR test A lot of first timers Pop a gel at the end of the swim Cold water after the swim Too eager to push a higher zone Once you overheat, there's no turning back Wind mind games It's all about being smart and patient Carrying nutrition on the run? Carrying ice Zip lock tricks When you're dehydrated and full Plain water on board? Body glide Wearing hats Your swim route (based on the map) The finish line vibe mike@c26triathlon.com robbie@c26triathlon.com
Episode 2659: Vinnie Tortorich and Chris Shaffer discuss three different topics that are all promoting mixed messages about health, and more. https://vinnietortorich.com/2025/06/promoting-mixed-messages-episode-2659 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH ALL THE PODCAST EPISODES ON YOUTUBE - Promoting Mixed Messages Chris discovered an article in VegNews: a vegan Italian cookbook. (5:00) They divert to a bit of Italian-American history, which has had its challenges. (6:00) Back to the VegNews article: They ponder how an Italian meal can be vegan. (12:15) Vinnie's family grew veggies, but all the Italian meals centered around meat. There was a keto trial—a small trial—but testing high cholesterol. (22:00) They discuss how many studies have been misrepresented by not including countries whose cultural diets contain a lot of meat. Blue Zones has been misrepresented as well. The diets vary, and the level of meat is far more than what tends to be represented. The one thing all the Blue Zone cultures have in common is an active outdoor lifestyle. (37:00) If you want to get rid of heart disease, you must get rid of processed foods. (38:00) Lean Mass Hyper Responders have a different starting point to consider. (40:00) High cholesterol (LDL) in and of itself is not necessarily a problem; you need to look at it in conjunction with other factors. (42:00) The ADA launched the American Obesity Association. Novo Nordisk has contributed funds to the ADA. Novo Nordisk is the company that brought us Wegovy. (51:00) GLP-1s are not a Magic Pill; if they were, they wouldn't have deadly side effects. (52:30) The ADA amended its guidelines to say that GLP-1s should be the “first line of defense” of correction for T2 diabetes, rather than lifestyle. (54:00) The ADA is disengenuous because it receives millions of dollars from Big Food corporations each year to *not* tell you to cut out sugar and processed foods. (55:00) The information the ADA gives cannot entirely be trusted because of the sources of funding it receives. Follow Vinnie on X @vinnietortorich. More News If you are interested in the NSNG® VIP group is currently closed for registration, but you can get on the wait list - Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. “Dirty Keto” is available on Amazon! You can purchase or rent it . Make sure you watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to You can order it from . Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! Don't forget you can invest in Anna's Eat Happy Kitchen through StartEngine. Details are at Eat Happy Kitchen. There's a new NSNG® Foods promo code you can use! The promo code ONLY works on the NSNG® Foods website, NOT on Amazon. https://nsngfoods.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere:
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