Podcasts about elevated

In this episode, Ayesha and Andrew discuss the June 17, 2026 issue of JBJS, along with an added dose of entertainment and pop culture. Listen at the gym, on your commute, or whenever your case is on hold! Link: JBJS website: https://jbjs.org/issue.php Sponsor: This episode is brought to you by JBJS Clinical Classroom. Subspecialties: Orthopaedic Essentials, Hip, Basic Science, Spine, Infection, Foot & Ankle, Education & Training, Shoulder Chapters (00:00:02) - Your Cases On Hold(00:01:42) - Top 10 in Orthopedic Surgery: The Legacy of Aaron Rosenberg(00:06:38) - Robinson on Research Expectations(00:18:12) - The role of research in the medical student curriculum(00:19:09) - Residency and the role of research in surgery(00:21:02) - Bone metabolic activity after total hip arthroplasty(00:29:19) - Periprosthetic Joint Infection after total knee arthropl(00:40:37) - Patients with pneumonia after total knee arthroplasty(00:48:57) - Deep Learning System for Lengthy Classification in Adolescent Idiopath

Nationwide Mutual's Senior Vice President and Chief Economist Kathy Bostjancic says the Fed may be approaching a neutral stance, but inflation is expected to remain above the 2% target through year-end. She sees the Fed holding steady for now, with rate cuts likely pushed into next year, while noting that reduced Fed communication could spark volatility even as the labor market and AI investment signal underlying economic strength.======== Schwab Network ========Empowering every investor and trader, every market day.Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/About Schwab Network - https://schwabnetwork.com/about

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The weekly radio show from Salvione, blending house, funk, and tech, resulting in an unparalleled energetic dance floor vibe. Alessio Mosti – No Puedo Seguir
I.g.n.a., Lady Vale – Club Life
Byred & Sandro Martins – You Know Me
Peter Romero – Wanna Talk
Paluma & Tyson O'Brien – In The AirBryan Vera – No Drama
Fran Ares, Sergiodnine – Starlight
Luka Kuhnow, Manuel De La Mare – Make Me (Manuel De La Mare Remix)
Most Some – Mustang (Blas Miller Mix)
MartinoResi, Carlos Arresa – Get That
MartinoResi, Esteban Angel – Who Is
Karretero – No Man
Davide T, Cyava – Pocket
Sam Frandisco – Gotta Have It

Where the Map Ends: The Finest MYSEA Yacht Charter Experiences Do Not Simply Show You the World. They Renew Your Sense of Wonder. Where the horizon begins to change.There is a moment, somewhere after the coastline disappears, when the world becomes impossibly quiet. Not silent. The sea is never silent but emptied of interruption; no traffic, no schedules, no performance. Only the sound of water moving against the hull and the peculiar awareness that life on land has fallen away behind you.Tim Clark, Senior Yacht Broker of MySea, joins the Elevated Magazines Podcast for an insightful conversation about bespoke, curated yacht charter experiences. Tim was introduced to the Superyacht industry at aged 19 when taking his first job as a Deckhand on a 65m charter yacht in Antibes. The seed was sewn! Tim went on to spend the next 10 years working on private and charter yachts in the summers, working his way up to Captain and spending the winter months at Solent University completing a BSc Hons degree in Maritime Studies. Tim came ashore in 1999 and joined Yachting Partners International as a trainee broker. After 5 years there he moved to join the start of what became Ocean independence as Senior broker and Charter Manager and after 9 years joined MYSEA to head up the UK Office.Learn more at MySea.co.Explore ElevatedMagazines.com/podcastListen on Spotify | Apple Podcasts | Amazon Music | YouTube | Pandora | iHeart

KMOX traffic reporter Rodger Brand explains the impact of the sinkhole at Broadway and Biddle which will necessitate a week-long closure of Interstate 44 through downtown St Louis. He was on with Megan Lynch.

Elevated issuance is still being met with strong investor demand   Follow Us Twitter @NYLInvestments Twitter @MacKayMuniMgrs Facebook @NYLInvestments LinkedIn: New York Life Investments LinkedIn: MacKay Municipal Managers Presented by New York Life Investmentswww.newyorklifeinvestments.com   MacKay Municipal Managers is a team of portfolio managers at MacKay Shields. MacKay Shields is 100% owned by NYLIM Holdings, which is wholly owned by New York Life Insurance Company. “New York Life Investments” is both a service mark, and the common trade name, of certain investment advisors affiliated with New York Life Insurance Company. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Matthew Tuttle remains a buyer of oil stocks, even as headlines Friday point to a U.S.-Iran deal never being closer. He sees the headwinds lasting for months, causing prices to stay elevated. Matt tells investors to keep an eye on "bottleneck names" and explains his stock picks in Rocket Lab (RKLB), Occidental Petroleum (OXY), and Solar Edge (SEDG).======== Schwab Network ========Empowering every investor and trader, every market day.Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/About Schwab Network - https://schwabnetwork.com/about

Trae Taylor Elevated to a 5 Star QB and Top 10 Player in the NationAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Send us Fan MailThis week Mike discusses elevated backgrounds in ICP-OES when analyzing high total dissolved solids (TDS) samples such as brines, digests, excipients, salts, and starting materials. TDS increases free electron density in the plasma, producing Bremsstrahlung (braking) radiation and recombination radiation, which raise a broad continuum background across the spectrum. The elevated background degrades signal-to-noise, increases blank standard deviation, and worsens detection limits, especially for elements with poor ICP-OES sensitivity. Mitigation approaches include dilution, matrix-matched calibration or standard additions when dilution isn't feasible.

Wilson County News Editor Nannette Kilbey- Smith shared this recipe. “I recently came across a little book by Helen Simpson, The London Ritz Book of Afternoon Tea, at a yard sale,” Nannette said. “Thumbing through it took me back to my years living in London and experiencing ‘afternoon tea' in various places. At one time during my years in England, I actually worked in a tea shop, where we served lunches, afternoon tea, and cream teas, including pretty sandwiches and gorgeous cakes. The menu also included seasonal soups, heartier sandwiches, and toasted treats, including this favorite, Welsh Rarebit. “A mix... Article Link

Elevated GP - Click here to join Elevated.GP Follow @dr.melissa_seibert on Instagram Dr. Peter Milgrom is Professor of Oral Health Sciences and Pediatric Dentistry in the School of Dentistry and adjunct Professor of Health Services in the School of Public Health at the University of Washington. He directs the Northwest Center to Reduce Oral Health Disparities. He holds academic appointments at Case Western University, University of Rochester, and University of California, San Francisco. He maintains a dental practice limited to the care of fearful patients and served as Director of the UW Dental Fears Research Clinic. Dr. Milgrom's work includes research on xylitol, the effectiveness of fluoride varnish and iodine in preschoolers, clinical efficacy and safety of diammine silver fluoride, motivational strategies to increase perinatal and well child dental visits in rural communities, and studies of cognitive interventions in pediatric and adult dental fear. The NIH, Maternal and Child Health Bureau, HRSA, and the Robert Wood Johnson Foundation support his work. Dr. Milgrom is author of 5 books and over 300 scientific articles. His latest book, Treating Fearful Dental Patients, was published in 2009.   Dr. Milgrom was Distinguished Dental Behavioral Scientist of the International Association for Dental Research for 1999. In 1999, and again in 2000, his work was recognized by the Giddon Award for research in the behavioral sciences in Dentistry. He received the Barrows Milk Award from IADR in 2000, recognizing his work for public health including the development of the Access to Baby and Child Dentistry (ABCD) program in Washington State. In 2003, Dr. Milgrom received a Special Commendation Award from the National Legal Aid and Defenders Association and the University of Washington Medical Center Martin Luther King, Jr. Community Service Award. In 2010, he received the Aubrey Sheiham Research Award for his work on xylitol. He serves on scientific review committees for the NIDCR, NIMHHD, NINDS, Center for Scientific Review at NIH and as a consultant to the FDA. In 2005, Dr. Milgrom was appointed the SAAD Visiting Professor of Pain and Anxiety Control at the King's College Dental Institute, University of London, UK for a six-year term. In 2008 he was awarded the degree of Doctor Honoris Causa from the University of Bergen, Norway in recognition of his work in social and behavioral dentistry. In 2012, he received the University of California, San Francisco Dental Alumni Gold Medal for his contributions to Dentistry. In 2012 he was also awarded the Norton Ross Award for Excellence in Clinical Research by the American Dental Association. In 2013, he was appointed to the Council of Scientific Affairs of the American Dental Association. In 2014, he received the Irwin M. Mandel Distinguished Mentor Award from the IADR. In 2015, he served as HMDP Expert in Dental Public Health for the Singapore Ministry of Health. Dr. Milgrom received his DDS from the University of California, San Francisco in 1972 and had a previous position at the National Academy of Sciences, Engineering, and Medicine. In the last few years, Dr. Milgrom has spoken to dental associations in Argentina, Colombia, Peru, Philippines, and USA and at major universities in USA and abroad.

A guide to diagnosing, imaging, and managing acute renal colic and nephrolithiasis in the ED. Hosts: Brian Gilberti, MD Avir Mitra, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Nephrolithiasis.mp3 Download Leave a Comment Tags: Kidney Stones, Urology Show Notes 1. CLINICAL CORE & PHYSIOLOGIC FRAMEWORK Epidemiologic Risk Profiles Lifetime incidence parameters hover around 1 in 11, presenting with a prominent male sex skew. Peak demographic manifestation concentrated within the 30–60 age band. High-yield temporal parameter: 50% recurrence vector within a 5-year post-initial-insult window. Mineralogical Composition Vectors Calcium oxalate crystals represent the predominant structural matrix. Struvite configurations (magnesium ammonium phosphate matrix) account for 1–2% of cohorts. Struvite stones function explicitly as infection-driven configurations secondary to upper tract proliferation; higher distribution index noted in female cohorts. Etiological & Modifiable Relational Dynamics Profound systemic dehydration or low baseline fluid throughput states. High-sodium diet structures and heavy animal-protein consumption loads. Positive genetic/familial history variables. Relative risk modulation: Each variable independently operates to expand baseline risk by a factor of 2x to 3x. Pathophysiologic Symptom Complexes Acute, sudden-onset, maximum-intensity (10/10) unilateral flank pain. Classic structural radiation vector tracking downward toward the ipsilateral groin/genitourinary dermatomes. Distinctive behavioral marker: Renal colic pacing/writhing behavior with zero antalgic position availability. Concomitant autonomic triggers: Nausea and emesis manifest in 50% of acute presentations. Physical Exam Discordance Metrics Severe subjective distress contrasted with a characteristically soft, completely non-tender abdominal palpation exam. CVA tenderness is completely variable and lacks reliable negative predictive value. Atypical Presentation Classifications Vague, poorly localized abdominal pain presentations occurring in up to 20% of active cases. Isolated lower urinary tract irritative signs including acute frequency or severe urgency. Incidental & Asymptomatic Dynamics Silent intrarenal or ureteral stones found incidentally. Longitudinal tracking demonstrates up to 33.3% of initially asymptomatic cohorts convert to fully symptomatic renal colic within a multi-year tracking window. 2. EXCLUSION DIAGNOSES & CRITICAL PATHWAY RED FLAGS Vascular Mimics: AAA rupture/expansion. This is a mandatory exclusion pathway in elderly cohorts presenting with acute flank or back pain. Physical tracking requires active exploration for an expansile, pulsatile abdominal mass. Gynecologic Emergencies: Ruptured ectopic pregnancy. Demands universal screening protocols via rapid beta-hCG testing in all female patients of childbearing potential presenting with lower abdominal/pelvic localization. Infectious Upper Tract Decompensation: Acute uncomplicated pyelonephritis. Differentiated via persistent high spikes, high fevers, systemic shaking chills, and profound pyuria. Genitourinary Structural Crises: Acute testicular torsion. Mandates a thorough, explicit scrotal/testicular structural exam if the flank pain radiates into the scrotum. Gastrointestinal and Adnexal Torsional Confounds: Acute appendicitis variants, acute mesenteric/bowel ischemia, and ovarian torsion syndromes. 3. LABORATORY TESTING & PHYSIOLOGIC EVALUATION Urinalysis Interpretation Nuances Microscopic or gross hematuria presents in approximately 66% to 90% of acute cases. Critical Pathological Caveat: Complete absence of hematuria documented in 20% to 33.3% of confirmed, acute obstructing ureteral stones. Diagnostic rule: A pristine urinalysis with zero red blood cells is entirely insufficient to exclude acute ureterolithiasis. Urinary pH as a Composition Clue Consistently low urinary pH parameters (pH < 5.5) point strongly toward a uric acid crystalline composition. Elevated urinary pH parameters (pH > 7.5) indicate the presence of urease-producing microbial pathogens, pointing toward a struvite infection stone. Infectious Screening Metrics Active tracking for marked pyuria, positive leukocyte esterase, and bacterial nitrites to rule out an obstructed, infected upper urinary tract system. BMP Immediate quantification of baseline serum creatinine to establish accurate eGFR values. Targeting detection of post-renal AKI from bilateral obstruction, unilateral obstruction in a single functioning kidney, or severe volume depletion. CBC Evaluation for marked leukocytosis. Physiologic Nuance: Mild-to-moderate white blood cell count elevations frequently represent non-specific stress demargination driven by severe pain and repetitive vomiting. High-grade white blood cell shifts demand immediate exclusion of systemic bacteremia or an infected, obstructed urinary system. Adjunctive Lab Pathways Rapid qualitative urine hCG testing. Reflex urine culture execution whenever urinalysis metrics display significant inflammatory profiles or clinical suspicion of UTI is high. 4. IMAGING MODALITIES & ALGORITHMIC CLINICAL SELECTION Non-Contrast CT Diagnostics Gold standard; diagnostic sensitivity and specificity parameters exceed 95% for stones >2 mm. Provides precise quantification of stone diameter (mm), exact localization (proximal, mid, or distal ureter), and degree of secondary hydronephrosis. Excellent structural visualization for detecting or ruling out alternate retroperitoneal, vascular, or intra-abdominal pathologies. Contrast-Enhanced CT Protocols Indicated when alternative intra-abdominal surgical pathology is highly suspected over isolated renal colic. Retains diagnostic capability to identify urinary tract stones >3 mm even within contrast-enhanced phases. NCCT Structural Architecture Limitations Standard stone protocol CT scans are executed in a prone position without IV contrast enhancement. It does not opacify the ureteral lumen. Presents a cumulative radiation exposure penalty when utilized serially across recurrent ED presentations. POCUS / Radiology Ultrasound Direct stone visualization capabilities are modest, operating at approximately 50% to 60% sensitivity, and is highly dependent on anatomical positioning at the extreme proximal ureter or the UVJ. Secondary obstruction tracking: Demonstration of hydronephrosis operates at a high sensitivity of approximately 80%. POCUS Clinical Utility Metrics Eliminates ionizing radiation exposure and allows immediate, rapid real-time execution directly at the patient’s bedside. Confirmation of significant hydronephrosis within a classic clinical presentation yields high post-test probability for stone presence while lowering suspicion for vascular catastrophes like a AAA. KUB Radiography Extremely poor overall diagnostic sensitivity, hovering around 57%. Fails to image radiolucent configurations (pure uric acid matrices) or small stones measuring

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The weekly radio show from Salvione, blending house, funk, and tech, resulting in an unparalleled energetic dance floor vibe. Paluma & Tyson O'Brien – In The Air
Bryan Vera – No Drama
Fran Ares, Sergiodnine – Starlight
Luka Kuhnow, Manuel De La Mare – Make Me (Manuel De La Mare Remix)
Most Some – Mustang (Blas Miller Mix)
MartinoResi, Carlos Arresa – Get ThatMartinoResi, Esteban Angel – Who Is
Karretero – No Man
Davide T, Cyava – Pocket
ATLAC – Hood Beat
Fer BR – Help Us!
The Fellas & Guzty – It's Just A Dream
JE:SAIS – 21 Questions
Peter Romero – Wanna Talk

Ex-Celtics Player Elevated To Vice President Of Basketball Operations With 76ers by Jaggy Sports

Recording date: 5th June 2026Global financial markets are exhibiting a striking disconnect between geopolitical risk and investor behavior, as major U.S. equity indices simultaneously reached record highs despite escalating tensions in the Strait of Hormuz. Ongoing missile exchanges and a fragile ceasefire between the United States and Iran have done little to unsettle equities, creating what market observers describe as a “Goldilocks” environment where negative macro risks are largely ignored. At the same time, attention has narrowed sharply toward the anticipated $75 billion SpaceX initial public offering, which is drawing liquidity away from bonds, Bitcoin, and commodities.The scale of the SpaceX IPO is expected to have meaningful mechanical effects on markets. With rapid inclusion into major indices, institutional investors are likely to position ahead of forced index buying, potentially diluting existing index constituents. This dynamic has contributed to strong performance in select equity sectors, particularly technology, while other asset classes lag.In contrast to declining gold and oil prices, copper has emerged as a standout performer. Supply-side constraints - including reduced production guidance from major miners such as Freeport-McMoRan, Ivanhoe Mines, and Codelco - have tightened the market. Additional risks stem from the Strait of Hormuz, a critical transit route for sulfuric acid used in copper processing. Stronger-than-expected industrial data from both the United States and China has further reinforced demand for the metal.Meanwhile, developments in the mining sector highlight emerging friction in global dealmaking. Chinese regulators have raised concerns that Zijin Mining's proposed acquisition of Allied Gold is overpriced, signalling potential constraints on future outbound mergers and acquisitions.Against this backdrop, investors are adopting a cautious stance. Elevated cash positions and expectations of summer volatility - driven by geopolitical uncertainty, IPO-related liquidity shifts, and seasonal commodity weakness - suggest that while markets appear calm, underlying risks remain significant.Sign up for Crux Investor: https://cruxinvestor.com

The U.S. economy added more jobs than expected in May, but the benefits were not evenly distributed. New labor market data shows Black workers continue to experience higher unemployment rates than white workers, while economists point to declining labor force participation and rising long-term unemployment as ongoing concerns. The report highlights persistent disparities that have remained in place for decades. Subscribe to our newsletter to stay informed with the latest news from a leading Black-owned & controlled media company: https://aurn.com/newsletter Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Send us a text and chime in!Elevated Fitness PV recently celebrated its ribbon cutting, marking the opening of a new private fitness studio in Prescott Valley. The studio offers personal training, small-group workouts, nutrition guidance, and accountability coaching for residents looking for a more focused fitness experience. Instead of a crowded gym setting, Elevated Fitness PV provides a supportive space where clients can work toward individual goals with guidance from a coach. Training at Elevated Fitness PV combines strength work and functional movement to help clients build confidence, improve everyday mobility, and create lasting routines. The studio also emphasizes consistency and community, encouraging members to stay...   For the written story, read here >> https://www.signalsaz.com/articles/elevated-fitness-pv-celebrates-ribbon-cutting-in-prescott-valley/ Check out the CAST11.com Website at: https://CAST11.com Follow the CAST11 Podcast Network on Facebook at: https://Facebook.com/CAST11AZFollow Cast11 Instagram at: https://www.instagram.com/cast11_podcast_network

Joe's Premium Subscription: www.standardgrain.comGrain Markets and Other Stuff Links —Apple PodcastsSpotifyTikTokYouTubeFutures and options trading involves risk of loss and is not suitable for everyone.Corn futures fell for a third straight session with the Dec26 contract settling near $4.67/bu—its lowest since late February—pressured by favorable Corn Belt weather and no Chinese buying since the mid-May summit.

This week on The Ash Heels, we welcome back Melanie Owner of Elevated Humidor Cigars & Cigar Rebel to kick off our Ladies Night Event happening right after this episode! We catch up with Melanie see what trends she's seeing in the cigar world & if events like this can bring more women off the sidelines of cigar smoking around the country. 

CardioNerds (Dr. Billy-Joe Mullinax, Dr. Dinu Balanescu, and Dr. Jane Ehret) discuss risk stratification in acute pulmonary embolism with Dr. Stavros Konstantinides, Chair of the 2019 ESC Pulmonary Embolism Guidelines. Using a real-world case, this episode explores how modern PE care has moved beyond “massive” and “submassive” labels toward a dynamic, physiology-based approach. The discussion highlights the limitations of static risk scores, the importance of right ventricular dysfunction and biomarkers, and why normotension does not imply stability. Special emphasis is placed on intermediate-high risk PE, early identification of impending hemodynamic collapse, and the role of lactate, serial reassessment, and PERT teams in guiding escalation of care. Audio editing by CardioNerds intern, Joshua Khorsandi.The 2026 American multi-society PE guidelines were published after this episode was recorded. Dr. Dinu Balanescu and Dr. Billy-Joe Mullinax are Co-chairs for the CardioNerds PE Series, developed in collaboration with the PERT Consortium.   Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Pulmonary Embolism PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls Stable blood pressure does not mean low risk in PEHypotension is a late finding. Patients may have severe RV failure, hypoxia, and tissue hypoperfusion while remaining normotensive — a key concept behind “normotensive shock.” Risk stratification in PE must be dynamic, not staticLegacy scores like PESI and Bova provide a snapshot and predict 30-day mortality, but they do not capture short-term trajectory or impending hemodynamic collapse. Intermediate-high risk PE is a dangerous and heterogeneous groupPatients with RV dysfunction, positive biomarkers, tachycardia, hypoxemia, and elevated lactate may have in-hospital mortality approaching 15%, rivaling STEMI. Lactate is a critical but underutilized marker in PEElevated lactate reflects tissue hypoxia and early circulatory failure and may identify patients at risk for collapse before blood pressure declines. PERT enables physiology-driven, patient-centered PE carePERT teams operationalize continuous reassessment, integrate imaging, labs, and clinical trajectory, and allow timely escalation — shifting PE management from rigid categories to real-time decision-making. Notes Drafted by Dr. Jane Ehret. 1. What is the contemporary framework for risk stratification in acute pulmonary embolism? Modern PE risk stratification prioritizes hemodynamics and right ventricular (RV) function rather than clot burden. The 2019 ESC Guidelines classify PE into high risk, intermediate risk (low vs high), and low risk, based on: Hemodynamic status, RV dysfunction on imaging, and Cardiac biomarkers. This framework emphasizes early mortality risk but requires clinical context to guide escalation decisions. 2. Why is normotension insufficient to define “stability” in PE? Blood pressure is a late marker of circulatory failure in PE. Patients can maintain normal BP through Tachycardia, Increased sympathetic tone, and RV compensation. Many patients with preserved BP may already have shock physiology, including hypoxemia, elevated lactate, and RV failure — sometimes referred to as “normotensive shock.” 3. How should intermediate-risk PE be conceptualized clinically? Intermediate-risk PE is heterogeneous, ranging from patients who do well on anticoagulation to those who deteriorate rapidly. Intermediate-high risk PE is defined by RV dysfunction on imaging and positive cardiac biomarkers. Clinical features such as tachycardia, increasing oxygen requirement, and elevated lactate identify patients at highest risk within this group. 4. What are the strengths and limitations of commonly used PE risk scores? Legacy scores are useful for initial risk categorization but are static and limited in predicting short-term deterioration. Most scores were developed to predict mortality or complications at fixed time points rather than dynamic clinical trajectory. 5. What are the commonly used risk scores and clinical tools in PE, and what is each designed to predict? ESC Risk Stratification Algorithm: Identifies high-risk PE by hemodynamics. Uses PESI or sPESI in normotensive patients to distinguish low-risk from non–low-risk PE. Uses RV dysfunction and biomarkers to differentiate intermediate-low from intermediate-high risk. Forms the basis of many institutional PE pathways. PESI and sPESI: Validated to predict 30-day mortality. Widely used to identify low-risk patients appropriate for outpatient management. Heavily influenced by age and comorbidities. Bova Score: Predicts 30-day PE-related complications in normotensive patients. Composite PE Shock Score (CPES): Predicts normotensive shock in hemodynamically stable PE patients. Pulmonary Embolism Progression (PEP) Score: Predicts progression from intermediate-risk to high-risk PE within 72 hours of diagnosis. PE Short-term Clinical Outcomes Risk Estimation (PE-SCORE): Predicts clinical deterioration or death within 5 days of PE diagnosis. Hestia Criteria: Identifies low-risk PE patients safe for outpatient treatment. Wells' Criteria and Revised Geneva Score: Determine pretest probability for diagnostic triage. PERC Score: Rules out PE in very low-risk patients. 6. What is the role of biomarkers in PE risk stratification? Troponin and natriuretic peptides reflect RV myocardial injury and strain. Current guidelines treat biomarkers as binary (positive vs negative), despite risk being continuous. Biomarkers are most helpful for: Initial risk classification. They are less useful for: Short-interval monitoring and Detecting rapid clinical deterioration. 7. Why is lactate an important physiologic marker in PE? Lactate reflects global tissue hypoxia and impaired perfusion. Elevated lactate may identify patients with: Early circulatory failure and Increased risk of imminent hemodynamic collapse. Lactate is not currently included in ESC risk algorithms but may add important prognostic information in intermediate-risk patients. 8. How does trajectory influence decision-making in PE management? Risk stratification should be viewed as a dynamic process, not a one-time label. Worsening clinical trajectory may include: Rising heart rate, Increasing oxygen needs, Rising lactate, and Progressive RV dysfunction. Serial reassessment is essential for timely escalation of care. 9. What role do Pulmonary Embolism Response Teams (PERT) play in risk stratification? PERT facilitates: Multidisciplinary decision-making and Integration of imaging, biomarkers, and clinical physiology. PERT is most valuable for: Intermediate-risk and high-risk PE and Patients with complex comorbidities or uncertain trajectory. PERT enables a shift from category-based to physiology-driven PE care. References 1. Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). Eur Respir J. 2019;54(3):1901647. Published 2019 Oct 9. doi:10.1183/13993003.01647-2019 2. Leidi A, Bex S, Righini M, Berner A, Grosgurin O, Marti C. Risk Stratification in Patients with Acute Pulmonary Embolism: Current Evidence and Perspectives. J Clin Med. 2022;11(9):2533. Published 2022 Apr 30. doi:10.3390/jcm11092533 3. Choi WH, Kwon SU, Jwa YJ, et al. The pulmonary embolism severity index in predicting the prognosis of patients with pulmonary embolism. Korean J Intern Med. 2009;24(2):123-127. doi:10.3904/kjim.2009.24.2.123 4. Jiménez D, Aujesky D, Moores L, et al. Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch Intern Med. 2010;170(15):1383-1389. doi:10.1001/archinternmed.2010.199 5. Chen X, Shao X, Zhang Y, et al. Assessment of the Bova score for risk stratification of acute normotensive pulmonary embolism: A systematic review and meta-analysis. Thromb Res. 2020;193:99-106. doi:10.1016/j.thromres.2020.05.047 6. Zhang RS, Yuriditsky E, Zhang P, et al. Composite Pulmonary Embolism Shock Score and Risk of Adverse Outcomes in Patients With Pulmonary Embolism. Circ Cardiovasc Interv. 2024;17(8):e014088. doi:10.1161/CIRCINTERVENTIONS.124.014088 7. Zhang RS, Alam U, Sharp ASP, et al. Validating the Composite Pulmonary Embolism Shock Score for Predicting Normotensive Shock in Intermediate-Risk Pulmonary Embolism. Circ Cardiovasc Interv. 2024;17(2):e013399. doi:10.1161/CIRCINTERVENTIONS.123.013399 8. Ehret J, Wakefield D, Badlam J, Antkowiak M, Erdreich B. Development of the Pulmonary Embolism Progression (PEP) score for predicting short-term clinical deterioration in intermediate-risk pulmonary embolism: a single-center retrospective study. J Thromb Thrombolysis. 2025;58(2):243-253. doi:10.1007/s11239-024-03051-5 9. Weekes AJ, Raper JD, Lupez K, et al. Development and validation of a prognostic tool: Pulmonary embolism short-term clinical outcomes risk estimation (PE-SCORE). PLoS One. 2021;16(11):e0260036. Published 2021 Nov 18. doi:10.1371/journal.pone.0260036 10. Zondag W, Hiddinga BI, Crobach MJ, et al. Hestia criteria can discriminate high- from low-risk patients with pulmonary embolism. Eur Respir J. 2013;41(3):588-592. doi:10.1183/09031936.00030412 11. Wells PS, Anderson DR, Rodger M, et al. Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and d-dimer. Ann Intern Med. 2001;135(2):98-107. doi:10.7326/0003-4819-135-2-200107170-00010 12. Wolf SJ, McCubbin TR, Feldhaus KM, Faragher JP, Adcock DM. Prospective validation of Wells Criteria in the evaluation of patients with suspected pulmonary embolism. Ann Emerg Med. 2004;44(5):503-510. doi:10.1016/j.annemergmed.2004.04.002 13. Le Gal G, Righini M, Roy PM, et al. Prediction of pulmonary embolism in the emergency department: the revised Geneva score. Ann Intern Med. 2006;144(3):165-171. doi:10.7326/0003-4819-144-3-200602070-00004 14. Kline JA, Mitchell AM, Kabrhel C, Richman PB, Courtney DM. Clinical criteria to prevent unnecessary diagnostic testing in emergency department patients with suspected pulmonary embolism. J Thromb Haemost. 2004;2(8):1247-1255. doi:10.1111/j.1538-7836.2004.00790.x 15. Kline JA, Courtney DM, Kabrhel C, et al. Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost. 2008;6(5):772-780. doi:10.1111/j.1538-7836.2008.02944.x

JB is in Perth, Billy is worried about the state of our team today, and we fire up the All Sports Report - as a Socceroo makes a last minute allegiance switch, and Billy butchers a netball team's name. Damian Barrett is in studio with his positives and negatives from Round 12, but the big question is - will he put on a Channel 7 pin? We want you to tell us something amazing you've done with Monday Brag Artist, Billy shares his five favourite moments from Triple M Footy this weekend, and Geelong is elevating a hall of famer to Legend Status. Collingwood's Jack Crisp is in studio ahead of the King's Birthday game, and ahead of International Donut Day. Finally, Billy has a dangerously fruity joke to close out our Monday show.See omnystudio.com/listener for privacy information.

The weekly radio show from Salvione, blending house, funk, and tech, resulting in an unparalleled energetic dance floor vibe. Sam Divine – The Groove
Nacho Scoppa – Summertime
Danilo Milani – Discotech
Rafa Barrios – Shake That Body
Mihalis Safras – Lesi
Justin Garcia – Me Encanta
Techouzer, Hermann Bravo – Chain Reaction
Davide T, Cyava – Pocket
Davide T, Cyava – Daily Race
David Lowe – The Drums
Castion – Move This
ATLAC – Hood Beat
Javi Galan, Manuel Torcello – Wanna Like That
Fer BR, Artslaves – Matiko (RSquared Remix)

Phosphate additives are commonly used in processed and convenience foods, yet many patients and healthcare professionals remain unaware of how significantly they contribute to phosphorus burden in chronic kidney disease (CKD). Elevated phosphorus levels can negatively impact bone, cardiovascular, and overall kidney health, making phosphorus management an important aspect of kidney care. In this episode of Kidney Commute, an interprofessional panel featuring a nephrologist, dietitian, policy expert, and patient advocate discusses the clinical impact of phosphate additives, the differences between naturally occurring phosphorus and additive-based phosphorus, and the practical challenges patients face when trying to identify hidden phosphorus sources in foods and medications. The discussion also explores socioeconomic barriers, food labeling limitations, and ongoing policy and advocacy efforts aimed at improving phosphorus transparency and patient education. Listeners will gain practical strategies and insights to better support phosphorus management in clinical practice and daily life.

Join Huntavore as he shares his passion for outdoor cooking, tailgating, and grilling with the Blackstone griddle. Discover tips on setup, menu ideas, and how to elevate your tailgate experience with creative hot dog and taco recipes.  This episode explores innovative cooking techniques, focusing on taco preparation, wild game utilization, and a French mustard cream sauce.  Nick shares practical tips, recipes, and insights to elevate home cooking and tailgating experiences.     Attribution Code "Slow Burn" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Join Huntavore as he shares his passion for outdoor cooking, tailgating, and grilling with the Blackstone griddle. Discover tips on setup, menu ideas, and how to elevate your tailgate experience with creative hot dog and taco recipes.  This episode explores innovative cooking techniques, focusing on taco preparation, wild game utilization, and a French mustard cream sauce.  Nick shares practical tips, recipes, and insights to elevate home cooking and tailgating experiences.     Attribution Code "Slow Burn" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Join Huntavore as he shares his passion for outdoor cooking, tailgating, and grilling with the Blackstone griddle. Discover tips on setup, menu ideas, and how to elevate your tailgate experience with creative hot dog and taco recipes.  This episode explores innovative cooking techniques, focusing on taco preparation, wild game utilization, and a French mustard cream sauce.  Nick shares practical tips, recipes, and insights to elevate home cooking and tailgating experiences.     Attribution Code "Slow Burn" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Small Cap Breaking News You Can't Miss!Here's a quick rundown of the latest updates from standout small-cap companies making big moves today:Power Metallic Mines Inc. (TSXV: PNPN) (OTCBB: PNPNF) (Frankfurt: IVV1)Power Metallic is expanding its summer 2026 exploration program at the Nisk Project in Quebec with three advanced geophysical surveys — SQUIDs, gravity, and Ambient Noise Tomography — designed to pinpoint deeper Ni-Cu-PGE mineralization. These surveys run alongside a 30,000-metre diamond drill program already being mobilized for Q2 and Q3 2026. Investors in the critical metals space should take note as the company systematically targets extensions to the high-grade Lion Zone and new discoveries across the enlarged land package.Minaurum Silver Inc. (TSXV: MGG) (OTCQX: MMRGF) (FSE: 78M0)Minaurum has reported high-grade drill results from the Europa Sur Vein Zone at the Alamos Silver Project in Sonora, Mexico, highlighted by 3.20 metres of 882 g/t silver equivalent including a peak of 2,423 g/t AgEq over 0.95 metres. Elevated gold and copper values suggest the presence of a high-temperature feeder structure, substantially boosting resource expansion potential within the ongoing 50,000-metre Phase II drill program. Alamos already hosts a 55.4 Moz AgEq inferred resource.Sitka Gold Corp. (TSXV: SIG) (FSE: 1RF) (OTCQX: SITKF)Sitka Gold's first 2026 drill hole at the Blackjack deposit returned 94.0 metres of 1.79 g/t gold including 19.3 metres of 5.04 g/t gold from 1,093 metres depth — the deepest hole ever completed at the RC Gold Project in Yukon. The result extends high-grade gold approximately 370 metres below the existing resource pit and confirms strong continuity with last year's deep discovery. With four rigs active on a fully funded 60,000-metre program, the company is rapidly advancing a district-scale gold system hosting over 5.1 million ounces across indicated and inferred resources.CopAur Minerals Inc. (TSXV: CPAU)CopAur released a Preliminary Economic Assessment and a 52% increase in Mineral Resource Estimate for its Kinsley Mountain Gold Project in Nevada, now totaling 742,000 indicated ounces at 1.11 g/t gold. At the current spot gold price of US$4,500/oz, the project delivers a post-tax NPV of US$147 million and an IRR of 66% with a 1.5-year payback on pre-production CAPEX of US$81.8 million. For a small-cap company with a modest market capitalization, owning 100% of a permitted Nevada heap-leach gold project with these economics represents a potentially significant value proposition.Bottom Line: Today's stories highlight a sector in full motion — high-grade silver and gold drilling campaigns advancing in Mexico and the Yukon, paired with a Nevada gold project delivering compelling PEA economics. Critical metals exploration and near-term gold production potential are the dominant themes.Stay ahead of the market — follow AGORACOM for more breaking small-cap news and insights.

Wakeboarding is small, winching is an even smaller part of that, and Hannah got into both within quick succession of one another. What happens when you get invited to go winching but can't really ollie yet? You go to the cable and learn. Hannah Littlefield is a great example of someone who doesn't get lost in the details of boarding, as seen by some of her riding setups over the years. Broken binding? Open toe rental boots at a winch spot? Board not waxed? No problem. Winching before you're honed, living at Elevated, being a girl in a boys club, ZMT films, print mags, being Gibbys big sister, and running your own business. Hear all that and much more in Episode 114 of the Grab Matters Podcast with Hannah Littlefield!Follow Hannah: https://www.instagram.com/hannah_littlefield/Thank you to this shows sponsors! Liquid Force: https://www.liquidforce.com/ Slingshot: https://slingshotsports.com/Support the show: https://www.patreon.com/GrabMattersPodcastChapters:00:00 - 2:30 Intro2:40 Favorite grab6:50 Guest Question: Gibson Corcoran11:00 First times winching 21:30 LF'n Hot Seat29:00 Living at Elevated 33:00 Winching with guys36:20 Guest Question: Matt Gagnon45:00 Slings Hot Takes51:00 Setup53:00 Contests58:10 Video Parts1:07:00 “Girl in a boys club”1:23:00 Nature of Offense1:29:40 Guest Question: Adam Sinclair1:45:00 Guest Question: Scot FerwerdaLinks: ZMT Films: https://www.youtube.com/@ZMT_Films/videosShe Sendz: https://www.instagram.com/she.sendz/Sewer Cats: https://www.youtube.com/watch?v=8jw7LgXjAco&t=144sShoot us a text!Patreon: https://www.patreon.com/GrabMattersPodcastWebsite: https://www.grabmatters.com/YouTube: https://www.youtube.com/@grabmatters/videosInstagram: https://www.instagram.com/grabmatters/TikTok: https://www.tiktok.com/@grabmatterspodcastFacebook: https://www.facebook.com/grabmatters

The housing market is diverging by region, not collapsing, with localized slowdowns and continued strength in states seeing strong migration. Katie Hubbard highlights regional dynamics, while Suzanne Miller notes demand is shaped more by economic uncertainty than mortgage rates. Builders are adapting with smaller homes and incentives, as the outlook depends on policy and the Fed.======== Schwab Network ========Empowering every investor and trader, every market day.Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/About Schwab Network - https://schwabnetwork.com/about

Freelance Railroading, Elevated. That's the new slogan from today's leading voice in freelance railroading, Home Shops. Owner Christopher Palmieri joins us and tells about a new partnership with a familiar name that has already started to elevate the offerings from Home Shops with a bunch of exciting annoucements. Chris tells us what he's looking for in a freelance railroading when planning projects and provides guidance for those looking to create their own plausible railroad. Later, Eric Hansmann stops by with the RPM Report and a familiar voice provides us with What's Trending. Learn more about this episode on our website:aroundthelayout.com/234This episode of Around The Layout is Powered By Rapido Trains:https://rapidotrains.com/Thank you to our episode sponsor, Spring Creek Model Trains:https://www.springcreekmodeltrains.com/Thank you to our episode sponsor, ModelTrainBox.com:https://modeltrainbox.com/Visit our website at aroundthelayout.comBecome a member of our Operating Crew for chances to win and much more!aroundthelayout.com/crewAround The Layout Podcast is a production of Thirty Five Productions LLC©2026 Thirty Five Productions LLC. All rights reserved.The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of Thirty Five Productions LLC or our sponsors.Use of any trademarks or trade names is for identification purposes only and does not imply endorsement.No portion of this podcast may be reproduced, distributed, or transmitted in any form or by any means without the prior written permission of Thirty Five Productions LLC, except for brief quotations used for purposes of review, commentary, or promotion.

Americans' confidence in the economy has taken a hit. AP correspondent Mike Hempen reports.

Told donor eggs after failed IVF? There is a category of testing that your fertility clinic does not run. We rarely run a stool test and find nothing. The IVF cycle did not work. Maybe it was poor response. Maybe it was canceled before retrieval. Maybe you got embryos and they arrested. Maybe the transfer failed. Your clinic looked at your numbers and told you donor eggs. In this episode, Sarah Clark walks through the gut pattern the Fab Fertile team sees in women who come to us after failed IVF with a donor egg recommendation, and why this pattern changes the picture before the next decision. What this episode covers: H. pylori. One of the most common findings in the women who come to us after failed IVF. It impairs absorption of iron, vitamin B12, and zinc, the nutrients that affect egg quality, thyroid function, and hormone production. It is passed back and forth between partners through saliva. If you have it, there is a strong chance your partner has it too. Parasites, giardia, blastocystis. Common findings. Rarely tested at the fertility clinic. Bacterial overgrowth, including streptococcus. Fungal overgrowth and dysbiosis. The reason chasing an anti-candida diet without testing moves you in circles. Elevated calprotectin. A signal of gut inflammation, often present in women with IBD, Crohn's, colitis, and women with no formal diagnosis. Elevated zonulin. A marker of intestinal permeability. The pattern we see after rounds of antibiotics, sinus infections, UTIs, birth control, and high stress. Why this matters before a donor egg decision: H. pylori impairs iron absorption. Ferritin reads low or low-normal. The clinic says iron is fine because the lab range starts around 15. The fertility-optimized range is closer to 50. Iron is foundational to egg quality. The oxygen carrying capacity to your follicles depends on it. B12 affects methylation, the process your body uses to produce the co-factors needed for egg maturation. Zinc affects ovulation and progesterone production. Chronic gut inflammation affects ovarian response to stimulation, implantation, and miscarriage risk. When your clinic looks at a canceled cycle, arrested embryos, or a failed transfer and recommends donor eggs, they are responding to the outcome. They are not asking what is driving the outcome. This episode is for the woman sitting with a donor egg recommendation who is not ready to agree before she understands what was actually evaluated. Next steps: Access the free guide: What Your Clinic Missed. It walks through the markers we review before a donor egg recommendation, including the thyroid panel, the iron panel with the fertility target, the gut testing your REI does not order, the inflammatory markers, and the male side. Email hello@fabfertile.ca, subject line MISSED. Book a Functional Fertility Second Opinion. We will review your labs, your history, your full picture, and your partner's picture together. You will leave knowing what your biology has been telling you and what your next decision should be informed by. Email hello@fabfertile.ca, subject line FERTILE. Or apply here. About the Host I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. My functional fertility team works with couples navigating low AMH and failed IVF, reviewing functional lab results, gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, toxin testing, and  bloodwork alongside nervous system work, to help identify patterns that may not have been considered. We work alongside your medical team, not instead of them. Subscribe to Get Pregnant Naturally for weekly episodes on fertility optimization, IVF preparation, and the lab work your doctor probably isn't running. Timestamps [00:00] Told Donor Eggs After Failed IVF [01:00] Why the Fab Fertile Team Reviews Your Picture [02:00] H. pylori: The Most Common Gut Finding We See [03:00] Parasites, Streptococcus, and the Bacteria Most REIs Do Not Test [04:00] Why a Single Gut Test Without Fertility Context Misses the Picture [05:00] Iron, Ferritin, and the Fertility Range vs the Lab Range [06:00] B12, Methylation, and Egg Maturation [07:00] Zinc, Ovulation, and Progesterone [08:00] What Your Clinic Missed: The Markers Before a Donor Egg Recommendation [09:00] Why a Donor Egg Recommendation Responds to the Outcome, Not the Cause [10:00] The Functional Fertility Second Opinion: What the Call Covers

The weekly radio show from Salvione, blending house, funk, and tech, resulting in an unparalleled energetic dance floor vibe. STELLA (ES) – Rapperhood Mendo, Angel Heredia – MIRA COMO BAILA ZULE PAZ – No Gender Feel This Diego Bustamante – On Me Now Boros – Drope Lucas Ferreyra, Arzenic – Bass E Bateria Fer BR, Angel Heredia – THAT LOUD Milo (CH) – Something Special Jay de Lys – Loaded Clipz (RSquared Remix) Cole Vassallo – Noises Castion – Non Stop Sergiodnine – Trigger Abraham (ES), S.Hai – Sxy Rafa Barrios – Conga

If you've ever looked at your prices and felt your stomach drop, you're not alone and you're not broken. I'm sitting down with Shaunice “Cece,” founder of Elevated Impact and a nervous system coach, to talk about the real reason so many women overwork, undercharge, and second-guess themselves even when the results are right in front of them.We get into what it actually means to feel seen and heard, and why that need doesn't make you “too much.” It makes you human. From the “evidence locker” (a simple way to fight imposter syndrome with receipts from your own life) to the messy work of boundaries and healthy detachment, we connect mental health to money mindset in a way that feels practical, not preachy. I also share how chronic illness and my endometriosis journey forced me to rebuild support, advocate for myself, and stop letting other people's comfort decide my limits.Then we go straight into the hard stuff: pricing your services, charging for speaking and expertise, and refusing unpaid opportunities that quietly devalue women entrepreneurs. Cece breaks down her action-oriented coaching style and how accountability helps you turn insight into real change. She also shares what she's building next, including a scholarship program that blends emotional wellness with money management and investing.If you're ready to earn with more self trust and less burnout, hit play, subscribe, share this with a friend, and leave a review so more women can find the tools that actually help.Send us Fan MailSupport the showSend us a textShop The Woman-Owned Wallet WebsiteWoman-Owned Brands all on WOW Directory!Find Grants Fast with SKIPFaire - List Your Business for WholesaleDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.

Small Business Administrator Kelly Loeffler acknowledged that Americans are facing increased prices but promised that the economy will be better than ever after the Iran War ends. “There's no question in recent weeks, prices have bumped up because of rising gas prices due to the Iranian blockade of the Strait of Hormuz now,” Loeffler told The Daily Signal in an exclusive interview. “Obviously, with gas prices bumping up, that does ripple through the supply chain.” But Loeffler said she's doing “everything we can in the meantime until the conclusion of this war, which we do believe is short term, to continue to alleviate the pressures of the Biden administration.” Learn more about your ad choices. Visit megaphone.fm/adchoices

For the love of the blender! Home made Lemonade, fluffy scrambled eggs, salsa - you name it. Jessica Merchant is stopping by to dish about her 4th cookbook, number one on Amazon: “Easy Everyday”. Elevated simple food recipes for the every day. Follow her @howsweeteats - My last bite: Miso Chili Noodles.

In this episode, Raj, Ashwin, and Eddie sit down with Dr. Vincent Rajkumar — Professor of Medicine at Mayo Clinic and Chair of the ECOG Myeloma Committee — for a clinically focused conversation on newly diagnosed multiple myeloma. Topics span baseline workup, risk stratification, induction selection, transplant timing, MRD-directed decision-making, and maintenance strategy. The episode closes with a discussion of Open Medicine, a new medical education platform, and Dr. Rajkumar's ongoing advocacy on drug pricing reform.KEY TOPICS DISCUSSEDBaseline workup: 24-hour urine protein: It is important to obtain 24-hour urine protein with electrophoresis and immunofixation in all newly diagnosed patients — not for diagnosis, but to establish a baseline for long-term management and to distinguish M-protein from albuminuria. In patients where an FLC ratio ≥100 is the sole myeloma-defining criterion, a 24-hour urine Bence Jones protein ≥200 mg is part of the diagnostic threshold for treatment initiation. Myeloma cast nephropathy: when to biopsy: An involved FLC ≥50 mg/dL supports a presumptive diagnosis of cast nephropathy and treatment can begin without a kidney biopsy. Below this threshold — particularly if renal involvement is the sole myeloma-defining event — kidney biopsy is warranted to exclude light chain deposition disease, MPGN, or other unrelated disorders. It warrants aggressive early treatment (Dara-VCD or Dara-VD), starting even before bone marrow results are available when the diagnosis is clinically clear.Solitary plasmacytoma [with or without minimal bone marrow involvement]: Patients with ~10% clonal plasma cells technically meet criteria for myeloma, but management in this borderline zone warrants shared decision-making. Solitary plasmacytoma as sitting between smoldering myeloma and overt myeloma on the disease spectrum. Risk stratification: revised IMWG criteria: The new revision aimed to keep the high-risk designation to ≤15–20% of patients. Del 17p alone confers high-risk status. TP53 mutation without del 17p is exceedingly rare and FISH alone captures the vast majority of cases. All other cytogenetic abnormalities (t(4;14), t(14;16), t(14;20), 1q gain, 1p deletion, biallelic 1p) require at least one co-occurring abnormality to define high risk. Elevated β2-microglobulin with normal renal function is retained as a proxy for high tumor burden. Emergent indications for treatment initiation: The three situations warranting urgent treatment are acute cast nephropathy (days matter for renal recovery), cord compression (surgery vs. radiation vs. systemic therapy determined by acuity), and hypercalcemia. Induction regimen selection: For fit, transplant-eligible patients, the preferred induction is a quadruplet — Dara-VRd or Isa-VRd — with dose adjustment as needed. Triplets (Dara-Rd or Isa-Rd) are reserved for those unable to tolerate a quadruplet even with dose reduction. Carfilzomib-based induction is not favored: head-to-head data show no benefit of KRd over VRd in NDMM, and the cost differential is substantial. Lenalidomide dosing: Starting dose should be individualized: 15 mg for patients over 75, those with small body habitus (

The weekly radio show from Salvione, blending house, funk, and tech, resulting in an unparalleled energetic dance floor vibe. -

Why do people no longer seem able to function in a society?Support the showWebsite: badattitudespod.comBad Attitudes Shop: badattitudesshop.etsy.comBecome a Member: ko-fi.com/badattitudespod Follow @badattitudespod on Instagram, Facebook, Threads, and BlueSkyBe sure to leave a rating or review wherever you listen!FairyNerdy: https://linktr.ee/fairynerdy

What happens when strong travel demand collides with rising costs and global uncertainty? April's data gives us a clearer picture—and it's more nuanced than you might expect. In this episode of The STR Data Lab, Jamie Lane and Bram Gallagher break down the latest U.S. short-term rental performance and what it signals for the critical summer season ahead.On the surface, the numbers look solid: ADR growth is outpacing inflation, demand continues to climb, and booking trends remain resilient. But beneath that strength are important signals hosts and operators can't ignore—elevated inflation, persistent interest rates, and a shifting supply landscape that could reshape competition in the months ahead.The conversation also dives into one of the biggest demand drivers of the year: the upcoming World Cup. While expectations may have started sky-high, the real story is how demand is spreading—not just across host cities, but into nearby “spillover” markets benefiting from longer stays and regional travel patterns. The result? A summer that's shaping up to be strong—but not without complexity.You don't want to miss this episode!Key Takeaways:ADR growth remains a bright spot: Existing operators are seeing ~6%+ year-over-year rate growth—outpacing inflation and signaling continued pricing power.Supply is accelerating (again): New listings are ramping up, especially in World Cup host markets, which could increase competition heading into peak season.Demand is steady—but not explosive: Overall demand is growing, though slightly trailing supply, leading to relatively flat occupancy levels.World Cup impact goes beyond host cities: Nearby and drive-to markets are seeing major “spillover” demand as travelers extend stays and explore multiple destinations.Macro factors still matter: Elevated inflation, high energy costs, and interest rate uncertainty could influence traveler behavior—especially for international bookings.Sign up for AirDNA for FREE

The New York City housing market is surging, with activity jumping as Frances Katzen points to strong bonus payouts and international demand. Douglas Elliman (DOUG) shows strength in ultra-luxury, while baby boomers drive a growing share of demand. Elevated rates remain a headwind, but supply constraints continue to support prices.======== Schwab Network ========Empowering every investor and trader, every market day.Options involve risks and are not suitable for all investors. Before trading, read the Options Disclosure Document. http://bit.ly/2v9tH6DSubscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/About Schwab Network - https://schwabnetwork.com/about

The latest inflation report shows price increases for American consumers in April hit a three-year high, driven by a spike in the cost of gasoline. The Consumer Price Index, which includes energy and food costs, rose 3.8% year-over-year, according to the Labor Department. Geoff Bennett discussed more with Heather Long, Chief Economist at Navy Federal Credit Union. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

 It’s estimated that 1 in 10 adults experience tinnitus, often described as a phantom ringing noise in the ears. The condition can develop due to head trauma, hearing loss, exposure to loud noise or as a side effect of certain medications.   There’s no cure for tinnitus and its origins have long been a mystery. But new research from Oregon Health & Science University has linked tinnitus with elevated serotonin levels in certain regions of the brain. While far from a cure, the discovery could one day help scientists understand how to reverse the condition through brain chemistry.   Larry Trussell is a professor of otolaryngology at OHSU and interim director of the Oregon Hearing Research Center. Angie Garinis is an associate professor of otolaryngology at OHSU and a member of the Oregon Hearing Research Center. She’s also a principal investigator at the National Center for Rehabilitative Auditory Research at the Portland VA.   They both join us to talk about what this new information could mean for patients who suffer from tinnitus.  

In this week's Slappin' Glass Deep Dive, we go deeper into one of the most important offensive conversations in the modern game: how to attack switching defenses.As switching continues to become a preferred solution for defenses at every level, offenses can no longer rely only on simply “getting the matchup” and hoping the possession solves itself. The best teams are finding ways to create the switch, organize spacing around it, and attack before the defense can load up, scram out, or triple switch its way back to neutral.In this episode, we explore the details behind turning a switch into a real advantage. From immediate mismatch attacks and early seals, to stampedes, clears, flares, pitches, short rolls, and corner skips, the conversation focuses on how offenses can punish the defense without becoming stagnant or predictable.We also discuss the importance of storytelling in teaching offense. The best concepts are not just a list of actions, but a way to help players understand the problem, recognize the advantage, and play with clarity inside the possession.For coaches looking to better understand modern spacing, mismatch creation, and late-clock problem solving, this Deep Dive offers a detailed look at how top teams are attacking one of basketball's most common defensive answers.What You'll Learn:How to attack switching defenses with more than just isolation We explore ways to punish switches through seals, stampedes, clears, flares, pitches, and short-roll solutions. Why timing matters after the switch happens The offense has a small window before the defense can load up, scram out, or triple switch back to neutral. How storytelling helps players understand offensive concepts The best teaching connects the action to the problem it solves, giving players more clarity and confidence inside the possession.To join coaches and championship winning staffs from the NBA to High School from over 70 different countries taking advantage of an SG Plus membership, visit HERE!

What does it actually look like to evolve from a successful photographer into a fully embodied luxury brand? In this deeply personal episode of the Play It Brave podcast, I'm taking you behind the scenes with my client and dear friend, Kristen Marie, as she walks through a massive identity shift, creative rebirth, and business rebrand. Kristen has been photographing weddings and adventure elopements for over eight years, and after years of success in the elopement world, her body finally told her something had to change. Together, we talk openly about burnout, redefining success, and the emotional process of growing out of an old identity that no longer fits. We also share what happened during Kristen's immersive coaching retreat at my cabin, where we explored her values, archetypes, subconscious beliefs, and the deeper emotional patterns underneath her business. Then, in a rare behind-the-scenes look, we bring you directly into one of Kristen's real coaching calls along with her brand designer, Kass. You'll hear us brainstorm everything from visual identity and positioning to luxury storytelling, artistic authority, nature-inspired branding, and what it truly means to create a brand that resonates instead of imitates. In this episode, we talk about: The hidden burnout that can happen even inside a successful photography business Why Kristen realized she could no longer continue as an overextended adventure elopement photographer How identity work and nervous system healing play a huge role in luxury rebranding The values and archetypes that shaped Kristen's new direction Moving from "cute girl with a camera" into grounded artistic authority The difference between copying luxury branding and creating true resonance Building a brand inspired by nature, stillness, cinematic storytelling, and emotional depth Why luxury positioning is often more about embodiment than skill level The visual and emotional references influencing Kristen's rebrand, from Ralph Lauren campaigns to Terrence Malick films How photographers can evolve their businesses without abandoning themselves in the process One of the biggest things I hope you take away from this episode is that rebranding is never just about aesthetics. It's not just new fonts, prettier colors, or a more elevated website. A true rebrand asks you to become honest about who you are now, who you've been, and who you're ready to become. Watching Kristen move through this process with so much courage, self-awareness, and openness has been incredibly beautiful. She's not simply trying to book higher-paying weddings. She's learning how to trust herself, honor her energy, deepen her artistry, and create a business that actually supports the life she wants to live. That's the kind of transformation that changes everything. I cannot wait for you to hear this behind-the-scenes conversation and witness what it really looks like to build a brand from the inside out. Click here for more ways to listen to this episode.

The guys dive into the different dynamics between players and the media, which leads into a discussion about Tua Tagovailoa and his struggles in press conferences last season along with his overall relationship with reporters. The conversation then shifts to the Miami Dolphins quarterback situation, with Malik Willis stepping in as the new starter and being described as an “elevated rookie” by Omar Kelly. The guys debate whether Quinn Ewers has any real shot at competing for the job or if Willis already has it locked up heading into the season. The segment wraps with a look at the Dolphins' offensive line, highlighting the significant investment the team has made with multiple first-round picks and whether that group can finally live up to expectations

9/16: Bridget Toomey and Bill Roggio discuss Ali Al-Zadei, a businessman elevated to Iraqi Prime Minister with Iranian support. While endorsed by Trump, his background in illicit finance raises concerns about ongoing militia influence.1920 BUSHER