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Mark Sullivan, Medicines for Global Health (MDGH), Melbourne, Australia, joins Jonathan to discuss global health inequality, the difficulties in finding funding as a Managing Director of a not-for-profit pharmaceutical company, and infectious diseases such as Hanson's disease and river blindness. Use the following timestamps to navigate the podcast topics: (00:00)-Introduction (01:55)-What led Sullivan into biochemistry and microbiology (03:04)-Sullivan's subsequent career in Pharma (04:36)-The world's only non-profit biopharmaceutical company (7:28)-Approval of moxidectin (14:15)-Hansen's Disease: causes, host response, and treatment (19:04)-Innovative medicines to treat the diseases of low- and middle-income countries (22:20)-How to tackle the enormous expenditure in low- and middle-income countries (30:56)-Product development partnerships (34:37)-How healthcare professionals can help (37:25)-Three wishes to improve global healthcare
Bill Lawrence from ReStore What did Zaire used to be called? What is River Blindness? What is less effective than DDT? Why would you dissect a fly? How do you dissect a fly? Why will we mine our own garbage? What items require special recycling? What is a “transfer station”? What is “planned obsolescence”? Who is leading the way with a “cradle-to-grave” philosophy?
28 December 2021: Helen speaks to Dubai residents who are isolating instead of celebrating during the holidays. She also gets the thoughts of family medicine doctor Ruhil Badiani on how we should deal with COVID anxiety during these hectic times. Dubai mum Jenny Mollon is seriously thinking about getting her kids vaccinated as cases continue to rise. Rika was disappointed that she wasn't able to fly home to South Africa but is making the most of her time in the UAE by exploring Expo. Surviving your in-laws: Are the holidays more stressful because of them? Dr. Thoraiya has a few tips to come out of this experience unscathed. Brain fog is real! That's what neuroscientist and psychologist Dr. Sabina Brennan wants to tell you through her book. The End Fund and the Gates Foundation have partnered to stamp out river blindness. See omnystudio.com/listener for privacy information.
Ready to really feel your skin crawl? Then this month's episode on Onchocerca volvulus, a parasite that is able to infiltrate into the eye and skin to cause intense itching and blindness, might just be the one for you! We'll learn all about why this communicable disease earned the nickname "River Blindness", its mysterious linkage to seizures, the awesome powers of ivermectin (when it's actually used for diseases it can treat), and how exactly a donkey falling into a river has helped hundreds of thousands of people. Tune in to learn more about the epidemiology, biology, and history of this infectious disease! Website: www.infectiouscast.com Twitter: @infectiouscast Instagram: @infectiouscast
In this classic TPWKY episode we travel down rivers and into worm-laden nodes as we take a look at the complex world of Onchocerca volvulus, the vector-borne parasite that causes river blindness. Join us as we learn why the name ‘river blindness’ captures only one dimension of the devastation caused by this parasite, how the short evolutionary history of this worm is at once surprising and enlightening, and why grasping the disease ecology of this system has been crucial in successful control efforts. As a bonus, if you tune in, you’ll get to hear how on earth The J. Geils Band fits into this story and the integral role that dog digestion has played in the history of this parasite. See omnystudio.com/listener for privacy information.
I catch up with Dr Geetha Manjunath, CEO & CTO of NIRAMAI, a deep-tech startup, offering a radiation-free, non-invasive, non-touch, breast cancer screening solution. I spoke to her back in Sept 2017 (Ep67) when they only had a handful of customers, now they are one of the top deep tech startups in India. In this episode we talk about their core technology called Thermalytix. How they have innovated during the pandemic. Talk about how they create AI/ML models and how they test them before production. Talk about scaling issues & being part of Google Launchpad and Phillips accelerators. How they have shortened the B2C sales life cycle from 6 months to 6 weeks. Thoughts on selling to hospitals. A deep dive on how do they train the machine when there is little data. She also talks about developing (AI)-based computer-aided software for controlling the spread of River Blindness with the help from Bill and Melinda Gates foundation. She takes a trip down memory lane and talks about being a member of the C-DAC team which built the first commercial indian supercomputer. And finally she gives great advice for first time entrepreneurs.In this conversation we also talk about:Talk about patents & IP.Being a thought leaderSupervised v Unsupervised learningLaunching a new B2C home screening serviceWorking with data augmentationThermal imagingTaking it to the villagesScaling from 1 to 10 then 10 to 100Using microservicesGetting in the shoes of the usersAre they still a startup?Major milestones reachedHealthcare startups take time!and much more!Linkshttps://www.niramai.com/P.Sif you need something to do during these challenging and difficult times and want some inspiration and need some creativity. check out Skillshare. Skillshare is an online learning community with thousands of classes in design, business, tech, and more. Anyone can join the millions of members in our community to learn cutting-edge skills, network with peers and discover new opportunities.Try Premium free for 2 months and access all my classes!https://www.skillshare.com/r/user/neilpatelmusic by Punch Deck. https://open.spotify.com/artist/7kdduxAVaFnbHJyNxl7FWV
In episode 1 of Science का Kura, we talk about actual research. Here, Himal, one of our co-hosts, shares his research experience in epidemiological modeling of a neglected tropical disease called River Blindness. Himal is currently doing a Ph.D. in Bioinformatics at La Trobe University, Melbourne, Australia. You can connect with Himal via LinkedIn (https://www.linkedin.com/in/himal-shrestha-35200373/) or Twitter(@himal2007). Being one of our co-hosts, you can also direct your queries to us (sciencekakura@gmail.com). We will make sure Himal will respond to the questions. Hear some exciting bits of his research @Science.ka.kura. --- Send in a voice message: https://podcasters.spotify.com/pod/show/sciencekakura/message
You've begun your fantastic foray into fitness and things are going great … until you just don't feel right one morning, and those droplets of doubt and worry start to creep into your mind. So, you grab your phone and start slamming in symptoms and that Doc in a Box Website of Doom That Shall Not Be Named tells you that you could have an assortment of ailments from a basic cold to lupus, polio, elbow cancer and River Blindness (it's a legit tropical disease … look it up). You flee to your physician only to have them throw some topical ointment at you and you can create your own Madlib here with their typical response: just calm down and (eat/drink) some (food/beverage) (more/less) than you currently do and perhaps add some (new superfood/cure-all compound) to your routine. About as helpful as a fork at a soup dinner, right? Worry not, friends – the LaBellaRX Ladies are here to help and have handy hints for handling the highs and lows of hormones: what they are, what they actually do and how they control a lot of things within our day to day lives. If you really want the secret to speed down the Highway of Health, catch this week's episode because understanding your hormones is an essential part of being your best self, both inside and out.
And our semi-finalist for this evening in the MacArthur Foundation's 100&Change Initiative is The Carter Center, and their proposal is to eliminate river blindness in Nigeria. And here to discuss that with us is Dr. Frank Richards, who is the Director of the River Blindness Elimination Program at The Carter Center.
It's a stomach-churning hypothesis based on previous research: The kinds of worms that affect hundreds of millions of people, mostly in the tropics, may be mitigating the most severe effects of COVID-19. Listen to DW's science podcast for a different angle on the coronavirus — five minutes every day from Germany.
There is a category of diseases that sickens, injures and kills the poorest people on the planet. These are called Neglected Tropical Diseases or NTDs You may be familiar with some of them, like leprosy, guinea worm disease or River Blindness; but you have probably never heard of most of them--I know I have not. But these diseases, combined, affect nearly 1.7 billion people around the world and further add to the costs of developing economies. So, in an effort to make these diseases a little less neglected, about eight years ago governments, philanthropies, UN agencies and NGOs came together to design and implement strategies to reduce and ultimately eliminate many of these diseases. On the line with me today is someone who has been at the very forefront of that effort. Dr. Thoko Elphick-Pooley is the director of a collective called Uniting to Combat NTDS. We discuss the progress that has been made towards the elimination of NTDs and also what strategies have been most effective in combating these diseases. As it happens, we spoke on the first-ever World NTD Day, so I kick off asking Dr. Elphick-Pooley about the significance of having a new world day around Neglected Tropical Diseases. https://www.undispatch.com/ https://www.undispatch.com/category/podcast/ https://www.globaldispatchespodcast.com/
In June 2018 the US FDA approved the drug moxidectin for the treatment of River Blindness. How did this drug with no market and no chance of profit get through FDA approval? This podcast is a tale of two cities; two people on opposite sides of the world came together to produce a new drug to treat the disease. Mark Sullivan, Founder & Managing Director of Medicines for Global Health and John Reeder, the Director of the Special Programme for Research and Training in Tropical Diseases tell us how this orphaned drug came to be and how it will contribute to the elimination of River Blindness.
Dr. Karp and Dr. Daniel Shungu discuss Onchocerciasis, also known as river blindness (Recorded April 28th, 2019).
In this episode, Sarah Frisch reads her story, "River Blindness." Off the Page is a podcast of stories, essays, and poetry from the Stanford University writing community, produced by the Stanford Storytelling Project in collaboration with the Stanford Creative Writing Program. Music by Breakmaster Cylinder Learn more at storytelling.stanford.edu and at creativewriting.stanford.edu
Dr Krystal joins Dr Shane in the studio. In news, cure for River Blindness approved by FDA and a discussion on whale sharks First guest is Dr Sarah Dunstan from the Peter Doherty Institute for Infection and Immunity. A study into the population and spread of tuberculosis-causing (TB) bacteria in Ho Chi Minh City, Vietnam, has found that more than half of cases can be attributed to one particular strain of the bacteria. A Melbourne-led international collaboration, sequenced the DNA from bacteria in TB patients Ho Chi Minh City. The findings concluded that the strain of TB-causing bacteria known as the Beijing lineage, was responsible for 59 per cent of infections. Second (and third) guests are Dr Mark Hulett and Dr Marc Kvansakul, from La Trobe Institute for Molecular Science. A team of scientists from Melbourne's La Trobe University has shown a protein found in a tobacco plant has the potential to fight life-threatening infectious diseases. The discovery could lead to the development of a new class of antibiotics and meet the challenge of rising antibiotic resistance. Third guest is Elaine Miles, Climate Data Analyst at the Bureau of Meteorology Melbourne Art conservationist and physicist with a PhD in Optics and Art Conservation, has monitored western style canvas paintings that were housed in the South East Asia region.
Academy Discourse by Professor William C. Campbell, Hon. MRIA is the third in the series sponsored by Mason Hayes & Curran. Ivermectin is a medication used in the treatment and control of parasitic diseases. In veterinary medicine, it is widely used in livestock and pets. It has several applications in human medicine, and has been notably successful in the prevention of River Blindness in the tropics. The discovery of ivermectin required innovation, yet rested on simple empirical science. It was a process from which lessons could be learned . . . but will they?
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin The TWiP Masters solve the case of the Australian Wildlife Carer, and review evidence that nodding syndrome may be caused by an autoimmune reaction to the parasitic worm that causes river blindness. Become a patron of TWiP. Links for this episode: Nodding syndrome an autoimmune disease? (Sci Transl Med) Nodding syndrome: Preventable and treatable (Sci Transl Med) River Blindness lyrics (Google Play) Image credit Letters read on TWiP 129 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase - WITH FREE SHIPPING - by going to blueapron.com/twip. Case Study for TWiP 129 Young male in 30s, presents to ER with male partner, NY area, chief complaint over 1 month significant diarrhea, watery, non bloody. Abdominal cramping. Feels poorly, low energy, fever. Some vomiting, lost noticeable amount of weight, can’t stay hydrated. Past: AIDS positive, not on meds, last CD4
เพลงเปิดเบบี้เวอร์ชั่น / ดราม่าอาบัน / รางวัลโนเบล สาขาการแพทย์ / โรคพยาธิตัวกลม / river blindness และ เท้าช้าง / พิธีประกาศรางวัลอิกโนเบล / รางวัลอิกโนเบล สาขาเคมี ทำไข่สุกให้กลายเป็นไข่ดิบ / อิกโนเบล สาขาฟิสิกส์ สรรพสัตว์ปัสสสาวะ ใช้เวลาเฉลี่ย 21 วินาที / ต่อครึ่งหลังโนเบลสาขาการแพทย์ ชีวิตและการค้นพบยารักษาโรคมาลาเรียของอาจารย์ถู โยวโยว SHOW NOTE รางวัลโนเบลสาขาการแพทย์ -1,2 https://www.youtube.com/watch?v=kxBe5t3V2e0 https://www.youtube.com/watch?v=8uqp3cnSAhY โรคจากพยาธิตัวกลม River Blindness (onchocerciasis) พยาธิตาบอด Elephantiasis เท้าช้าง คุณ Satochi Omura เจอแบคทีเรีย Streptomyces avermitilis ฆ่าพยาธิได้ คุณ William Campbell สกัดสาร avermectin และดัดแปลงเป็นยา ivermectin โครงการแจกยาให้คน https://www.youtube.com/watch?v=t96_xbpXH-M พยาธิหนอนหัวใจในหมา IG NOBEL 2015 วิดิโอโปรโม พิธีประกาศรางวัล https://www.youtube.com/watch?v=D6JhEFNrmk0 https://www.youtube.com/watch?v=MqVCl2VoZqU รางวัลอิกโนเบล สาขาเคมี มอบแก่ทีมวิจัยผู้ค้นพบวิธีการ ทำให้ไข่สุก ย้อนกลับกลายเป็นไข่ดิบได้ (ประมาณนึง) -1,2,3,4,5 REFERENCE: "Shear-Stress-Mediated Refolding of Proteins from Aggregates and Inclusion Bodies," https://www.youtube.com/watch?v=CHMY4G9gTPA รางวัลอิกโนเบล สาขาฟิสิกส์ มอบแก่ทีมวิจัย ผู้ค้นพบว่าสัตว์เลี้ยงลูกด้วยนมเล็กใหญ่เกือบทุกชนิดใช้เวลาฉี่เท่ากัน คือประมาณ 21 วินาที + - 13 วินาที -1,2,3 REFERENCE: "Duration of Urination Does Not Change With Body Size," Patricia J. Yang, Jonathan Pham, Jerome Choo, and David L. Hu, Proceedings of the National Academy of Sciences, vol. 111 no. 33, August 19, 2014, pp. 11932–11937. hydrostatic pressure กลับมารางวัลโนเบลการแพทย์ ว่าด้วยยารักษามาลาเรีย เรื่องราวชีวิตของอาจารย์ถู โยวโยว และการค้นพบ artemisinin -1,2,3,4,5,6 A Handbook of Prescriptions for Emergencies by Ge Hong (284–346 CE). https://www.facebook.com/witcastthailand/photos/a.384378794958298.93979.380263635369814/1037871079609063/?type=3
Neglected tropical diseases afflict some of the world's most isolated communities. Yet they are not as obscure as many people think – the blinding bacterial disease trachoma existed in the United States and Europe until the early-20th century, and river blindness was brought to the Americas from Africa through the slave trade. Carter Center experts discuss how fighting these horrific, yet preventable diseases impact poverty and improve global health.
Merck had spent many years developing a drug to combat a variety of diseases in farm animals. After Merck began selling the drug for use as a veterinary medicine, a scientist at the company discovered that it might also be extremely effective in fighting river blindness, a human disease that plagued millions in the Third World. Vagelos knew that developing the drug for human use would be time consuming, expensive and risky; he also knew that virtually none of the communities afflicted with river blindness would be able to afford to buy the drug. Vagelos nonetheless instructed Merck to proceed with the research. His decision would lead to the Mectizan Donation Program (MDP), which has overseen the donation of more than 1 billion treatments to more than 117,000 communities in 28 countries in Africa, six countries in Latin America, and in Yemen. The program has served as a model for corporate social responsibility ever since.This is the first of four lectures of the HSBC student series on ethics and accountability: Bringing today's ethical challenges to tomorrow's business leaders.
Merck had spent many years developing a drug to combat a variety of diseases in farm animals. After Merck began selling the drug for use as a veterinary medicine, a scientist at the company discovered that it might also be extremely effective in fighting river blindness, a human disease that plagued millions in the Third World. Vagelos knew that developing the drug for human use would be time consuming, expensive and risky; he also knew that virtually none of the communities afflicted with river blindness would be able to afford to buy the drug. Vagelos nonetheless instructed Merck to proceed with the research. His decision would lead to the Mectizan Donation Program (MDP), which has overseen the donation of more than 1 billion treatments to more than 117,000 communities in 28 countries in Africa, six countries in Latin America, and in Yemen. The program has served as a model for corporate social responsibility ever since.This is the first of four lectures of the HSBC student series on ethics and accountability: Bringing today's ethical challenges to tomorrow's business leaders.
The parasitic worm onchocerciasis carries uses a bacterial cloaking device to colonize the human body, causing tremendous suffering and even blindness. Luckily, the Carter Center is waging a campaign against the parasite. Tune in to learn more. Learn more about your ad-choices at https://news.iheart.com/podcast-advertisers
Watch video footage from "Dark Forest Black Fly," which documents efforts to eliminate river blindness from Uganda; listen to a panel discussion about the challenges of eliminating the disease and experiences making the film.
Former U.S. President Jimmy Carter discusses current Carter Center peace and health initiatives around the world.
David Molyneux introduces the Neglected Tropical Diseases Series.
Drug studies are showing that treatment for onchocerciasis, also known as river blindness, could help to eliminate this debilitating skin disease. River blindness affects 37 million people, mostly living in poor, rural African communities.
We find out how a cocktail of chemicals in Black Fly saliva could offer a cure for River Blindness, discover that Jackdaws know when they're being watched, and that Chimps exchange meat for sex! Plus, Sarah Castor-Perry explores this week in science history...
In the dense forests of Uganda, the fight against river blindness follows an especially challenging mission. Watch public health specialists from The Carter Center as they journey to the black fly's breeding area, discover how freshwater crabs play a unique role in the life cycle of the insect, and learn how dedicated field workers devote tireless efforts to the demanding job of eradicating the fly and the terrible disease it carries. 10/1/2008
In the dense forests of Uganda, the fight against river blindness follows an especially challenging mission. Watch public health specialists from The Carter Center as they journey to the black fly's breeding area, discover how freshwater crabs play a unique role in the life cycle of the insect, and learn how dedicated field workers devote tireless efforts to the demanding job of eradicating the fly and the terrible disease it carries. 10/1/2008
An overview of the Carter Center's battle against river blindness.