Hosted by Dr. Thomas Slavin, Senior Vice President of Medical Affairs for Myriad Oncology, Inside the GENOME will be exploring the world of cutting-edge cancer genetics. Dr. Slavin will interview those on the front lines of cancer, and those advancing the science of cancer prevention, diagnosis, and treatment. Inside the GENOME - Genetics, Oncology and Me.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
In this episode Dr. Slavin sits down with Chris Jacobs, Founder and former-CEO of Gateway genomics to discuss exciting advances for parents to be.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Taylor Kane shares her family's story from her father being affected by ALD when she was a child and what that means for her and her future as a carrier of this condition
Ashley Pantier has two children with SMA and shares her family's journey and how carrier screening gave them the knowledge they needed in diagnosing her children with SMA
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.Websites Referenced:https://pubmed.ncbi.nlm.nih.gov/25503495/https://pubmed.ncbi.nlm.nih.gov/11746004/https://pubmed.ncbi.nlm.nih.gov/34459979/https://www.nature.com/articles/s41431-018-0285-1https://pubmed.ncbi.nlm.nih.gov/31553108/https://pubmed.ncbi.nlm.nih.gov/29158769/https://pubmed.ncbi.nlm.nih.gov/33420344/https://www.clinicalgenome.org/genomeconnect/for-patients-genomeconnect/https://uclawreview.org/2021/04/06/medical-malpractice-the-custom-based-standard-vs-the-reasonable-physician-standard/https://pubmed.ncbi.nlm.nih.gov/30578420/.https://www.oncotarget.com/article/26501/https://journals.sagepub.com/doi/pdf/10.1177/1073110520916994https://pubmed.ncbi.nlm.nih.gov/32154515/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.Non-profit organization for the ovarian cancer community and clinical trials: https://www.clearityfoundation.org/ Clinical Trials: https://forms.clearityfoundation.org/find-clinical-trials/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Dr. Ifey Stitt is a board certified OB-GYN dedicated to women's health, with special interest in genetics and education. She practices in Annapolis, Maryland and is affiliated with Luminis health where she serves as medical director for her group.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
In this episode, Dr. Slavin welcomes Dr. Mattie Crutchfield. They discuss her journey from considering genetic testing to learning she is a PALB2 mutation carrier and how she is taking action to reduce her cancer risk.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.References for this episode:https://fenwayhealth.org/the-fenway-institute/education/the-national-lgbtia-health-education-center/https://transcare.ucsf.edu/guidelinesBRCA care: https://journals.lww.com/greenjournal/Fulltext/2021/12000/Creating_Breast_and_Gynecologic_Cancer_Guidelines.16.aspx#:~:text=As%20breast%20surgery%20often%20leaves,rather%20than%20traditional%20chest%20masculinization.Free course about teaching LGBTQ+: Healthhttps://mededucation.stanford.edu/courses/teaching-lgbtq-health/https://fenwayhealth.org/the-fenway-institute/education/advancing-excellence-in-sexual-and-gender-minority-health/train-the-trainer-course/https://www.kff.org/other/issue-brief/youth-access-to-gender-affirming-care-the-federal-and-state-policy-landscape/https://www.aclu.org/legislation-affecting-lgbtq-rights-across-country
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.References for this episode:Kerlilowske reference: JCO 2010. https://pubmed.ncbi.nlm.nih.gov/20644098/Other suggested articles from Dr. Pederson: Automated Quantitative Measures of Terminal Duct Lobular Unit Involution and Breast Cancer Risk https://pubmed.ncbi.nlm.nih.gov/32917665/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.References for this episode:Genome web article: https://www.genomeweb.com/sequencing/early-cancer-detection-li-fraumeni-syndrome-patients-enabled-liquid-biopsy-testAbstract: https://acmg.planion.com/Web.User/AbstractDet?ACCOUNT=ACMG&CONF=AM22&ssoOverride=OFF&ABSID=12124CHARM consortium https://charmconsortium.ca/NCCN Guidelines: https://www.nccn.org/professionals/physician_gls/pdf/genetics_bop.pdfTumor-Based Genetic Testing and Familial Cancer Risk https://pubmed.ncbi.nlm.nih.gov/31570381https://liftupstudy.org/https://ascopubs.org/doi/abs/10.1200/JCO.2020.38.15_suppl.1514
In this episode Dr. Slavin welcomes Dr. Judy Garber, Professor of Medicine at Harvard Medical School, Chief of Division of Cancer Genetics and Prevention at the Dana Farber Institute, and Susan F. Smith Chair. Together, they discuss the OlympiA study and outcomes that have influenced industry guidelines.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.References for this episode:https://genesight.com/for-clinicians/clinical-studies/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.References for this episode:https://ocrahope.org/2021/05/highlights-2021-virtual-annual-meeting-of-sgo/https://www.cancernetwork.com/conference/sgoList of accepted abstracts from 23rd Annual American Society of Breast Surgeons https://www.breastsurgeons.org/meeting/2022/https://www.breastsurgeons.org/meeting/2022/docs/2022_Official_Proceedings_ASBrS.pdfKurian et al paper. https://jamanetwork.com/journals/jama/article-abstract/2600457Highlights From the Miami Breast Cancer Conference 2022— Co-chair Debu Tripathy, MD, provides an overview of the studies discussed at the meetinghttps://www.medpagetoday.com/meetingcoverage/mbcc-video-pearls/97669Abstracts:https://www.cancernetwork.com/journals/mbcc-suppl/38th-annual-miami-breast-cancer-conference-abstracts-miami-breast-cancer-conference-abstract-supplements
It has been more than twenty years since the collapse of the World Trade Center on September 11th, 2001. Dr. Slavin discusses Myriad Genetics' company-wide involvement in the effort to help identify victims of the tragedy with John Ryan, Sr. VP of Operations, Women's Health and Oncology, and Benoît Leclair, Program Director of Quality Assurance and Regulatory Affairs.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.References for this episode:https://education.asco.org/coursecollection/genetics-and-genomicsCOH-Registration now openhttps://www.cityofhope.org/education/health-professional-education/cancer-genomics-education-program/intensive-course-in-cancer-risk-assessment-overviewhttps://online.stanford.edu/programs/genetics-and-genomics-programhttps://www.nurseportfolio.org/Medical Breast Training Program - Mayo, Cleveland Clinic and Women's College of Toronto : https://ce.mayo.edu/online-education/content/medical-breast-training-program-all-sessions#group-tabs-node-course-default2https://www.ons.org/learning-libraries/precision-oncologyDiversification of Nurse Practitioner Practice: Genetic Cancer Risk Assessmenthttps://www.sciencedirect.com/science/article/pii/S1555415520301276?via%3Dihubhttps://www.duq.edu/academics/schools/nursing/faculty/grants/genomic-competencies-for-nurses-from-theory-to-application-an-online-course#:~:text=This%20professional%20development%20opportunity%20is,year%2C%20each%20spring%20and%20fall.https://myriad-oncology.com/continuing-education-webinars/The Myriad Oncology RMS team also leads a series via webinar for GC's and Nurses "Evolving Strategies in Hereditary Cancer". These can be viewed live by invitation. contact your local RMS team to get on that invite list. Also these are available on demand after the live presentation at our webpage https://myriad-oncology.com/continuing-education-webinars/https://www.gimjournal.org/multimedia/audio#:~:text=GenePod%20is%20the%20podcast%20from,content%20from%20this%20leading%20journal.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.References for this episode:Open Access: Addressing Reproductive Healthcare Disparities through Equitable Carrier Screening: Medical Racism and Genetic Discrimination in United States' History Highlights the Needs for Change in Obstetrical Genetics Care https://www.mdpi.com/2075-4698/12/2/33ACMG poster. eP336: A tale of two HBs: DNA Sequencing and hemoglobin electrophoresis. https://www.gimjournal.org/article/S1098-3600(22)00388-4/fulltextThe Evolving Role of Next-Generation Sequencing in Screening and Diagnosis of Hemoglobinopathies. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353275/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
In this episode, Dr. Slavin speaks with breast surgeon Dr. Allison DiPasquale, Director of Breast Oncology at Medical City Dallas and Board President of the Susan G. Komen Dallas County Chapter. They discuss the role of genetics in breast cancer treatment and prevention.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.Links referenced and shared in this episode:https://www.nccn.org/professionals/physician_gls/pdf/kidney.pdfBratslavsky et al. Genetic risk assessment for hereditary renal cell carcinoma: Clinical consensus statement. Cancer. 2021 Nov 1;127(21):3957-3966. doi: 10.1002/cncr.33679. Epub 2021 Aug 3. https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.33679Carlo MI, Mukherjee S, Mandelker D, et al. Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma. JAMA Oncol. 2018;4(9):1228-1235. doi:10.1001/jamaoncol.2018.1986 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584283/Cryoablation versus Partial Nephrectomy for Clinical Stage T1 Renal Masses: A Systematic Review and Meta-Analysis, https://pubmed.ncbi.nlm.nih.gov/30854132/https://pubmed.ncbi.nlm.nih.gov/34882627/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930334/https://ascopubs.org/doi/abs/10.1200/PO.20.00118
In this episode, Dr. Slavin hosts Dr. Tin-Yun Tang, a current hematology and oncology fellow at MD Anderson Cancer Center. Together, they discuss what programs and training can look like for physicians interested in genetics research and Dr. Tang's efforts in genomic research during his combined internal medicine and clinical genetics and genomics residency at Case Western Reserve University.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
In this episode, Dr. Slavin welcomes Leigha Senter-Jamieson, MS, CGC, to the podcast. As an Associate Professor of Internal Medicine, Associate Director of the Division of Human Genetics, and the Ohio State University Genetic Counseling Graduate Program Associate Director she discusses hereditary testing and offers her unique insight into the emerging role of genetic counselors in tumor testing.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
In this episode, Dr. Slavin welcomes Dr. Todd Cohen, Vice President of Medical Affairs for the Myriad Urology department. Dr. Cohen formerly practiced with Hawes Urology before pursuing an academic role as the Assistant Chairman of Urology at Ohio State University. He then co-founded Piedmont Urology in Charlotte, NC before forming Carolina Urology Partners, a merging of nine urology groups, where he acted as co-CEO, then CEO. Myriad Genetics welcomed Dr. Cohen in his leadership role in March of 2019. Dr. Cohen brings his many years of expertise to the discussion regarding genomics, the role of gene expression assays, and the treatment of prostate cancer.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.Additional resources cited in this episode:Hu et al NEJM - A population based study of genes previously implicated in Breast Cancer 2021. https://www.nejm.org/doi/pdf/10.1056/NEJMoa2005936Palmer et al. JNCI paper - Contribution of Germline Predisposition Gene Mutations to Breast Cancer Risk in African American Women. https://pubmed.ncbi.nlm.nih.gov/32427313/Antoniou et al NEJM - Breast caner risk in families with mutations in PALB2 2014. https://pubmed.ncbi.nlm.nih.gov/25099575/Yang et al 2020 PALB2 paper Dr. Couch referenced https://pubmed.ncbi.nlm.nih.gov/31841383/BCAC study - NEJM 2021 https://www.nejm.org/doi/full/10.1056/nejmoa1913948Narod editorial to these two papers - CARRIERS and BCAC. https://www.nejm.org/doi/full/10.1056/NEJMe2035083?query=recirc_curatedRelated_articleBCAC Study paper titled: Breast Cancer Risk Genes - Association in More than 113,000 Women CARRIERS study is titled - A Population Based Study of Genes Previously Implicated in Breast Cancer
In this episode, Dr. Slavin welcomes medical oncologist and researcher, Adam Brufsky, MD, PhD, FACP. He is a professor of medicine at the University of Pittsburgh School of Medicine and co-director of the Comprehensive Breast Cancer Center. Dr. Brufsky has been an innovator involved with breast cancer research for many years. Together, they discuss breast cancer gene expression assays and the role it plays in treating breast cancer.
In this episode of Inside the Genome, Dr. Slavin talks with Dr. Karen Hurley. Dr. Hurley is a licensed clinical psychologist in the Center for Adult Behavioral Health at the Cleveland Clinic in Ohio. She has given numerous presentations on patients' psychosocial situations as they experience the genetic testing process.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.Many studies were referenced in this episode, please see links below:Yanes T, et al. Clinical applications of Polygenic breast cancer risk: a critical review and perspective of an emerging field. Breast Cancer Res 22, 21 (2020). https://pubmed.ncbi.nlm.nih.gov/32066492/ Mars et al study link: https://www.nature.com/articles/s41467-020-19966-5Rosner et al study: https://cebp.aacrjournals.org/content/cebp/early/2020/12/04/1055-9965.EPI-20-0900.full.pdfLakeman et al study: https://www.nature.com/articles/s41436-020-0884-4Barnes et al study: https://www.nature.com/articles/s41436-020-0862-x https://www.nature.com/articles/ng.3841https://pubmed.ncbi.nlm.nih.gov/25862352/This is the study where the chart comes from : https://pubmed.ncbi.nlm.nih.gov/32620971/Here is the abstract from ASCO about ancestrally unbiased breast cancer (BC) risk assessment. Dr. Pederson also presented this material during the meeting. https://meetinglibrary.asco.org/record/197017/abstractHere is the Tischkowitz paper Dr. Slavin was discussing: https://www.acmg.net/PDFLibrary/41436_2021_1151_OnlinePDF.pdfGallagher paper (chart was from this paper) https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2767768 Yanes T, et al. Women's responses and understanding of polygenic breast cancer risk information. Fam Cancer. 2020 Oct;19(4):297-306. https://pubmed.ncbi.nlm.nih.gov/32430685/https://cancerpreventionresearch.aacrjournals.org/content/early/2020/10/23/1940-6207.CAPR-20-0154?versioned=trueHughes et al paper where data from chart is derived: https://ascopubs.org/doi/full/10.1200/PO.20.00246Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score https://ascopubs.org/doi/full/10.1200/JCO.20.01992Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer https://www.nejm.org/doi/full/10.1056/NEJMoa2105215
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