National Institute for Health and Care Research

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The National Institute for Health and Care Research (NIHR): funding, enabling and delivering world-class health and care research that transforms people's lives. Visit our website: www.nihr.ac.uk

NIHR


    • Jun 9, 2021 LATEST EPISODE
    • infrequent NEW EPISODES
    • 8m AVG DURATION
    • 97 EPISODES


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    Latest episodes from National Institute for Health and Care Research

    Professor Tim Maughan- Stratified medicine studies: lessons from running the adaptive FOCUS 4 trial.

    Play Episode Listen Later Jun 9, 2021 15:43


    Professor of clinical oncology at the University of Oxford and Clinical Director of the Oxford Institute for Radiation Oncology - Stratified medicine studies: what we have learnt from the set-up and delivery of the adaptive FOCUS 4 trial. Transcript: https://docs.google.com/document/d/1kkNeISk15owBsojhUk68ypHnUueDDcGnD6kv3by_L4w/edit

    Dr Emma Gray Development of the MAMS trial ‘Octopus' for people with progressive MS

    Play Episode Listen Later Apr 21, 2021 16:23


    Dr Emma Gray Assistant Director of Research at the MS Society Development of the multi-arm, multi-stage trial ‘Octopus' for people with progressive MS www.mssociety.org.uk/stop-ms Transcript:https://docs.google.com/document/d/1kaoWeiRiZr7kZczP1omst2FvYWbwVun4VIN2MIzCHfU/edit?pli=1

    Dr Hugh Davies How the C-19 pandemic & clinical experience can be a new preface to clinical research

    Play Episode Listen Later Mar 24, 2021 11:31


    Dr Hugh Davies chair of the Oxford research ethics committee and was formerly a research ethics advisor to the health research authority. Dr. Davies trained in medicine and was a consultant paediatrician for many years. Transcript: https://docs.google.com/document/d/1JJR0JF_1jPKOoxN45M-xZtD8obbEWd9S3ezHKR5f-K0/edit?usp=sharing

    Professor Matt Sydes - The importance of communicating trial results to the study participants.

    Play Episode Listen Later Mar 17, 2021 12:37


    Matt Sydes Professor of Clinical Trials and Methodology at the MRC Clinical Trials Unit at University College London. The importance of communicating trial results to the study participants. Transcript:https://docs.google.com/document/d/1_tCdh1o9gWFsu5yXeTyXf8JDozGWF4qNrVTspeWNoFA/edit?usp=sharing

    Professor Sir Munir Pirmohamed The NHS, UK's not so secret weapon in delivering Covid-19 research

    Play Episode Listen Later Mar 10, 2021 13:35


    Professor Sir Munir Pirmohamed - The NHS, the UK's not so secret weapon in delivering Covid-19 research. COVID-19 - the importance of embedding research and the clinical care interface as a whole, working seamlessly together, to improve future outcomes for patients. Transcript:https://docs.google.com/document/d/1tvGNL5rWd7t3NVbtWy1z8HJPzVPfZR9db-NgwmRCXf8/edit?usp=sharing

    Professor Thomas Jaki - The AGILE initiative and the advantages and challenges of Platform Trials.

    Play Episode Listen Later Mar 3, 2021 8:47


    Professor Thomas Jaki - Professor of Statistics at Lancaster University and Programme Leader at the MRC Biostatistics Unit at the University of Cambridge The AGILE initiative and the advantages and challenges of Platform Trials. Transcript: https://docs.google.com/document/d/1ad6R8yTfRsdna7Wk442ybKHwPB4h5oZF3WzUqqEMubw/edit?usp=sharing

    Professor Pam Kearns - The CATALYST trial: Accelerating drug development for COVID-19

    Play Episode Listen Later Feb 24, 2021 10:39


    Professor Pam Kearns, Director of the Cancer Research UK Clinical Trials Unit, University of Birmingham The CATALYST trial: Accelerating drug development for COVID-19 Transcript: https://docs.google.com/document/d/1h5c5C15kiTqsPEJPoHXkbcDTD_hbhIBNzSQjQavteLk/edit?usp=sharing

    Dr Camille Carroll - The role of digital technology, in clinical trials.

    Play Episode Listen Later Feb 17, 2021 15:27


    Dr Camille Carroll Associate Professor and Honorary Consultant Neurologist Peninsula Medical School (Faculty of Health). NSL for Neurology NIHR CRN The role of digital technology, such as sensors and wearables, in clinical trials. Transcript https://docs.google.com/document/d/1OwnBt7efXXCn3-DpefjIukDHtrrXYzEg9XmzXfhZQoc/edit?usp=sharing

    Kirsty Wydenbach Challenges and advice for CID trials, and how COVID-19 has impacted the MHRA.

    Play Episode Listen Later Feb 10, 2021 12:20


    Dr Kirsty Wydenbach deputy unit manager and senior medical assessor at the clinical trials unit in the MHRA Challenges and advice for complex innovative design trials, and how COVID-19 has impacted on the MHRAs approach. Transcript:https://docs.google.com/document/d/1HS-c3mR-B4m3RCtRpWHb5kIS8Xv90XJ2IIReWOg4fpw/edit?usp=sharing

    Yan Yiannakou - Running a wholly virtual trial during the COVID-19 pandemic.

    Play Episode Listen Later Feb 3, 2021 12:15


    Yan Yiannakou Clinical Director of the NIHR Patient Recruitment Centre – Newcastle Running a wholly virtual trial during the COVID19 pandemic. Transcript: https://docs.google.com/document/d/1_HkW3ixWip1XtrqUAGeiinQX7J3divCC1tKo_X_HUWg/edit?usp=sharing

    Emma Lowe - Innovation in clinical research during the COVID pandemic

    Play Episode Listen Later Jan 27, 2021 12:47


    Emma Lowe - acting head of research policy for clinical research and growth at the UK department of health and social care (DHSC) - focus on the Innovation in delivery of research studies during the COVID pandemic. Transcript: https://docs.google.com/document/d/13XO3AK7ar2co34e0zT-jPWZ-iI88xavLaqzXo0O09DE/edit?usp=sharing

    Trailer - Innovation in Trial Design and Study Delivery during the COVID pandemic Podcast Series II

    Play Episode Listen Later Jan 18, 2021 1:17


    Following on from our first round of podcasts that evolved from the recommendations in the paper; Effective delivery of Complex Innovative Design (CID) cancer trials- a consensus statement focusing on complex innovative design trials the NIHR CRN coordinating center has again collaborated with the Health Research Authority and in this series, the NIHR Office for Clinical Research Infrastructure. This time, we will be discussing some of the key learning points from the COVID-19 pandemic, such as: - Has the recent success using innovative design and delivery of research studies during the COVID pandemic been part due to the advance of innovation in trials pre-COVID-19? Could Continuous Improvement mean innovation in COVID-19 research inform studies post the pandemic? And how can we evidence this? The general learnings and happenings throughout the COVID-19 pandemic, and we will be building on the further questions around the management and delivery of innovative design trials during the pandemic. From Weds 27th January we will roll out a weekly podcast here aimed at anyone with an interest in designing, delivering or reviewing Innovation in Trail Design and Study Delivery. They are presented by experienced research professionals from across the research environment. The research delivery infrastructure in the UK provided by the NIHR, working closely with the NHS, regulators and stakeholders, continues to deliver unparalleled clinical research activity to address the COVID-19 pandemic. Agility, coordination and innovation are core attributes that are driving this impact made by our clinical research. They are also attributes that will ensure the UK can regrow the comprehensive health and social care research portfolio as soon as the harm of the COVID-19 pandemic upon health and social care is overcome. Drawing upon proven research infrastructure and our culture of continuous improvement from recent experience (such as those shared in this podcast series) provides this platform for future success.

    Kelly Fricker: working as GP practice research nurse

    Play Episode Listen Later Aug 13, 2020 5:14


    Kelly Fricker is the lead research nurse at The Boathouse Surgery in Pangbourne, Reading. Here she speaks about what her role involves, studies into conditions such as arthritis and chronic obstructive pulmonary disease (COPD) and how her team are able to carry out research in their GP practice with the support of the National Institute for Health Research (NIHR).

    Emma Lowe — Discusses the definition of complex and innovative trials

    Play Episode Listen Later Jul 6, 2020 15:22


    Emma Lowe Dept. of Health and Social Care and CID Trials as she discusses the definition of complex innovative trials and on the role of the Dept. of Health and Social Care.

    Prof. Julie Lovegrove and Nutritional Research

    Play Episode Listen Later Feb 20, 2020 16:09


    Prof. Julie Lovegrove and Nutritional Research by NIHR

    Prof. Martin Rossor and Dementia Research

    Play Episode Listen Later Jan 16, 2020 12:15


    Martin's clinical research interests are in the degenerative dementias, particularly familial disease, and more recently in general cognitive impairment in systemic disease and multimorbidity. He established the Queen Square Dementia Research Centre and has served as the editor of the Journal of Neurology, Neurosurgery and Psychiatry, President of the Association of British Neurologists, Director of the NIHR Clinical Research Network for Dementia and Neurodegenerative diseases (DeNDRoN), and Director of the NIHR Queen Square Dementia Biomedical Research Unit. As part of the activities of DeNDRoN he established Join Dementia Research (JDR), a national system for linking patients and public to research studies. He has served on numerous advisory boards and is currently an associate member of the World Dementia Council, member of the 2020 Dementia Programme Board, and Chairman of the Senate for the German Centre for Neurodegenerative Diseases (DZNE).

    Katherine Cowan

    Play Episode Listen Later Jan 10, 2020 16:36


    Katherine Cowan by NIHR

    Prof. Irene Higginson and Palliative Care Research

    Play Episode Listen Later Dec 19, 2019 15:17


    Prof. Irene Higginson and Palliative Care Research

    Peter Bower Multimorbidity

    Play Episode Listen Later Nov 6, 2019 14:30


    Peter Bower Multimorbidity by NIHR

    Clare Meachin 70 @ 70

    Play Episode Listen Later Oct 17, 2019 12:17


    Clare Meachin 70 @ 70 by NIHR

    Prof. Sally Wyke and Health Research Involving Complex Interventions

    Play Episode Listen Later Sep 19, 2019 18:39


    Sally Wyke, Interdisciplinary Professor of Health and Wellbeing at the University of Glasgow talks about complex interventions to improve health.

    Dr Fiona Thistlethwaite and Advanced Therapies In Clinical Research

    Play Episode Listen Later Aug 15, 2019 16:10


    Dr Fiona Thistlethwaite and Advanced Therapies In Clinical Research by NIHR

    Dr Matthew Hobbs And The Role Of Single Disease Medical Charities In Research

    Play Episode Listen Later Jul 18, 2019 18:51


    Dr Matthew Hobbs And The Role Of Single Disease Medical Charities In Research by NIHR

    Dr Hugh Davies and Research Ethics Committees

    Play Episode Listen Later Jun 20, 2019 14:05


    Dr Hugh Davies and Research Ethics Committees

    Jennifer Martin (MHRA) And Clive Collett (HRA) And EConsent

    Play Episode Listen Later May 16, 2019 14:03


    Jennifer Martin (MHRA) And Clive Collett (HRA) And EConsent by NIHR

    Primary Care Research With Prof. Philip Evans

    Play Episode Listen Later Apr 18, 2019 12:07


    Primary Care Research With Prof. Philip Evans by NIHR

    prof nihr philip evans primary care research
    Joanne Ashcroft and Non-traditional Settings for Clinical Research

    Play Episode Listen Later Mar 21, 2019 19:04


    Joanne Ashcroft and Non-traditional Settings for Clinical Research

    Kate Searle talking about Highlight: Management of Labour

    Play Episode Listen Later Mar 18, 2019 5:26


    Kate Searle talks about how the new Highlight from the NIHR: Management of Labour would have been beneficial reading for her before the birth of her third child.

    Prof. Patricia Connolly and Medical Device Research

    Play Episode Listen Later Feb 21, 2019 11:51


    Prof. Patricia Connolly and Medical Device Research

    Medical Devices With Prof. Patricia Connolly

    Play Episode Listen Later Feb 21, 2019 11:43


    Medical Devices With Prof. Patricia Connolly by NIHR

    Clinical Trials Of Vaccines With Prof. Helen McShane

    Play Episode Listen Later Jan 17, 2019 10:42


    Clinical Trials Of Vaccines With Prof. Helen McShane

    Dr Mike Clark and Social Care Research

    Play Episode Listen Later Dec 20, 2018 16:02


    Dr Mike Clark and Social Care Research by NIHR

    Prof. Janet Peacock and Medical Statistics

    Play Episode Listen Later Oct 18, 2018 11:06


    Prof. Janet Peacock and Medical Statistics by NIHR

    Research THIS: Digital Health

    Play Episode Listen Later Aug 29, 2018 14:47


    Professor Jeremy Wyatt on why the NIHR is seeking to fund more research into Digital Health and what kind of proposals they would like to see.

    Prof. Sandra Eldridge and Pragmatic Clinical Trials

    Play Episode Listen Later Aug 15, 2018 13:58


    Prof. Sandra Eldridge and Pragmatic Clinical Trials by NIHR

    Allan and Richard Smith discuss misconduct and fraud in clinical research.

    Play Episode Listen Later Aug 2, 2018 11:20


    Allan and Richard Smith discuss misconduct and fraud in clinical research. by NIHR

    Compassion in clinical research with Dr de Zulueta

    Play Episode Listen Later Aug 2, 2018 12:18


    Compassion in clinical research with Dr de Zulueta by NIHR

    Jonathan Sheffield International Clinical Trials Day

    Play Episode Listen Later Aug 2, 2018 8:06


    Jonathan Sheffield International Clinical Trials Day by NIHR

    Dr Fiona O'Neill and the Development of the Clinical Research Workforce

    Play Episode Listen Later Aug 2, 2018 10:44


    Dr Fiona O'Neill and the Development of the Clinical Research Workforce by NIHR

    Multi-arm, Multi-stage Clinical Trials with Prof. Allan Hackshaw

    Play Episode Listen Later Aug 2, 2018 8:30


    Multi-arm, Multi-stage Clinical Trials with Prof. Allan Hackshaw by NIHR

    Dr Jonathan Sheffield Stratified Medicine

    Play Episode Listen Later Aug 2, 2018 11:27


    Dr Jonathan Sheffield Stratified Medicine by NIHR

    Shona McDermott Educational Needs of Researchers

    Play Episode Listen Later Jul 31, 2018 17:24


    Shona McDermott Educational Needs of Researchers by NIHR

    MHRA GCP Inspections with Jason Wakelin-Smith

    Play Episode Listen Later Jul 25, 2018 14:16


    MHRA GCP Inspections with Jason Wakelin-Smith by NIHR

    Research Priority Setting Partnerships with Katherine Cowan

    Play Episode Listen Later Jul 19, 2018 16:36


    Research Priority Setting Partnerships with Katherine Cowan

    Clinical Research and Brexit with Prof. Emma Cave

    Play Episode Listen Later Jul 17, 2018 14:20


    Clinical Research and Brexit with Prof. Emma Cave

    Ethical considerations in genetic research with Prof. Nalin Thakker

    Play Episode Listen Later Jul 17, 2018 16:01


    Ethical considerations in genetic research with Prof. Nalin Thakker

    Systematic Reviews and Meta-analyses with Prof Mike Clarke

    Play Episode Listen Later Jul 17, 2018 11:26


    Systematic Reviews and Meta-analyses with Prof Mike Clarke — Director of the MRC Methodology Hub at the Centre for Public Health in Queen's University Belfast. Virtual Journal Club Link: Investigation of bias in meta-analyses due to selective inclusion of trial effect estimates: empirical study bmjopen.bmj.com/content/6/4/e011863.full

    Challenges and Opportunities in Large-scale Trials with Prof David Newby

    Play Episode Listen Later Jul 17, 2018 12:21


    Challenges and Opportunities in Large-scale Trials with Prof David Newby

    The Role of the Research Funder with Prof Sir Nilesh Samani

    Play Episode Listen Later Jul 17, 2018 13:51


    The Role of the Research Funder with Prof Sir Nilesh Samani by NIHR

    Patient and Public Involvement with Mr Simon Denegri

    Play Episode Listen Later Jul 17, 2018 10:43


    Simon Denegri OBE, National Institute for Health Research (NIHR) National Director for Patients, Carers and the Public.

    The Nurse's Changing Role In Clinical Research With Dr Susan Hamer

    Play Episode Listen Later Jul 17, 2018 7:21


    The Nurse's Changing Role in Clinical Research with Dr Susan Hamer — Director of Nursing, Learning and Organisational Development at the National Institute for Health Research Clinical Research Network Coordinating Centre.

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