Podcasts about Medical statistics

As we approach the end of Pride month, Jade explores how the pharmaceutical industry can best support staff and patients who identify as part of the LGBTQ+ community. She talks with Edmond Chan, Senior Director, EMEA Therapeutic Area Lead, Haemato-Oncology, J&J, who shares his personal views on how the industry can improve health outcomes and encourage authenticity.  In this interview, they discuss how both the pharmaceutical and healthcare industries can do their best to support people from the LGBTQ+ community, the unique challenges that patients and staff may face and more.   A little more on GOLD's guest…  Edmond has been with J&J for just over ten years, starting in pharmacovigilance before moving into medical affairs. During this time, he has worked in the areas of diabetes and immunology before recently settling into his current area of expertise, haemato-oncology.   Edmond also works as an ABPI final signatory and holds a PhD in Medical Research in Therapeutic Antibodies as well as a Masters in Medical Statistics. He also has 12 years' experience in clinical practice.   At the heart of all these academic and professional achievements, Ed is also a proud member of the LGBTQ+ community and strives to be a role model for other members. 

Professor Karl Roberts, University of New England, NSW, Australia gives a talk on generative AI and large language models as applied to healthcare. Dr Karl Roberts is the Head of the School of Health and Professor of Health and Wellbeing at the University of New England, NSW, Australia. Karl has over thirty years-experience working in academia at institutions in Australia, the UK and USA. He has also acted as an advisor for various international bodies and governments on issues related to wellbeing, violence prevention and professional practice. Notably, this has included working with policing agencies, developing policy and practice on suicide, stalking, and homicide prevention. Interpol developing guidance for organisational responses to deliberate events such as biological weapon use. The UK government SAGE advisory group throughout the Covid19 pandemic focusing upon security planning. The European Union advising on biological terrorism, and extremist use of AI. World Health Organisation where he worked in a unit developing policy and practice related to deliberate biological threat events. There has been substantial recent interest in the benefits and risks of artificial intelligence (AI). This has ranged from extolling its virtues as a harmless aid to decision making, as a tool in research, and as a means of improving economic productivity. To those claiming that unchecked AI is a significant threat to human wellbeing and could be an existential threat to humanity. One area of significant recent advancement in AI has been the field of Large Language Models (LLMs). Exemplified by tools such as Chat-GPT, or DALL-E, these so-called generative AI models allow individuals to generate new outputs through interacting with the models using simple natural language inputs. Various versions of LLMs have been applied to healthcare, and have variously been shown to be useful in areas as diverse as case formulation, diagnosis, novel drug discovery, and policy development. However, as with any new technology, there is a potential 'darkside,' and it is possible to utilise these tools for nefarious purposes. This talk will give a brief introduction to generative AI and large language models as applied to healthcare. It will then discuss the potential for misuse of these models, seeking to highlight how they may be misused and how significant a threat they could pose to health security. Finally we will consider strategies for managing the risks set against the possible benefits of generative AI. This talk is based on work carried out by the author and colleagues at the World Health Organisation and the Royal United Services Institute.

Caution was expressed at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting about potential adverse effects from one form of breast cancer treatment de-escalation. A poster warns about risks from omitting axillary sentinel node surgery in older women. In this edition of OncTimesTalk correspondent Peter Goodwin hears about axillary dissection in older women with clinically node-negative breast cancer from Mariam Rana, MD, FRCSC, Oncology Surgeon with the University of Saskatchewan in Canada College of Medicine, in discussion with Robert Hills, DPhil, Chair of Medical Statistics at Oxford University Nuffield Department of Population Health, who leads the secretariat for the Early Breast Cancer Trialists' Collaborative Group. They discuss Rana’s ASCO poster that found the omission of axillary surgery to stage the axilla may be associated with a higher risk of overall mortality in older women with early-stage breast cancer, compared to those who have this surgery.

STAMPEDE is a long-running trial in advanced prostate cancer, in which nearly 12,000 men have taken part. Thanks to its multi-arm multi-stage platform design, STAMPEDE has tested many different treatments and directly led to improvements in the standard of prostate cancer care several times. This Trial Talk podcast mini-series will explore the trial's journey from its inception in the early 2000s to the end of patient recruitment in March 2023. Part 1 covers the landscape of prostate cancer treatment before STAMPEDE, as well how the trial was designed, featuring two researchers who lead the methodological and clinical sides of the trial: Max Parmar, Professor of Medical Statistics and Epidemiology and Director of the MRC Clinical Trials Unit at UCL and UCL's Institute of Clinical Trials and Methodology, and Nick James, Professor of Prostate and Bladder Cancer Research at the Institute of Cancer Research. - Further information is available on the STAMPEDE study page at www.mrcctu.ucl.ac.uk For questions or feedback on the series, message us at mrcctu.engage@ucl.ac.uk For more information and to access the transcript: https://bit.ly/3OQWhV8 As a listener, your opinion is very valuable to us. Please help us to improve the podcast in future by filling in this short survey: forms.office.com/e/PjfjQ5Mn6g

Viscosupplementation is a procedure that involves injections of hyaluronic acid, most commonly into the knee joint. In the United States, one in every seven people receive a hyaluronic acid injection as first line treatment for their knee osteoarthritis. However, the effectiveness and safety of viscosupplementation has remained controversial. On this week's episode of Joint Action, we are joined by Bruno da Costa to discuss viscosupplementation, their effectiveness and safety.Dr. Bruno R. da Costa is Deputy Director of Trial Methodology Program at Nuffield Department of Population Health, University of Oxford, and Associate Professor of Clinical Epidemiology at the Institute of Health Policy, Management and Evaluation, University of Toronto. He has a Ph.D. in Clinical Epidemiology and Biostatistics from the University of Bern in Switzerland, a M.Sc. in Medical Statistics from the University of Leicester in the UK, and a M.Sc. in Physical Therapy from the University of Alberta in Canada. Dr. da Costa is considered to be an influential scientist in the field of musculoskeletal and cardiovascular disease and methodological research on comparative effectiveness. He has co-authored over 100 scholarly peer-reviewed publications, which have been published in prominent peer-reviewed scientific journals such as The New England Journal of Medicine, The Lancet, Journal of the American Medical Association (JAMA), and The BMJ.RESOURCESViscosupplementation for knee osteoarthritis: systematic review and meta-analysisCONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.

Colson Steber is the Co-CEO of Communications for Research, a research logistics company that simplifies and gives you confidence in recruiting and data collection operations, and he is the Co-CEO of Ag Access. He is experienced in implementing strategies and market research and was an Adjunct Professor in Medical Statistics for Rush University Medical Center and a Personal Finance Instructor for the University of Missouri.  Colson graduated from the University of Missouri-Columbia with his MBA and the University of Missouri Trulaske College of Business with a bachelor's in finance and economics. He is a member of the Entrepreneurs' Organization of St. Louis. In this episode… As an entrepreneur, your schedule can have little wiggle room, so when it comes to making connections and building relationships, how can you do so efficiently? Is it possible to stay on track with your marketing strategy? When you're launching a product that took an enormous amount of time and money, you want to make sure that you've thoroughly researched your audience. Developing and executing strategies to maximize the benefits for your consumers and brand includes building relationships. For Colson Steber, building relationships means curating relationships and opportunities. The first step in thinking about ways to add value to yourself and your work for others is showing up. So, are you ready to move forward? In this episode of Access To Anyone, Michael Roderick sits down with Colson Steber, Co-CEO of Communications for Research, to discuss breaking through the walls of entrepreneurial poverty through relationship building. Colson talks about establishing habits for growth, programming your environment, and being thoughtful about your relationships. 

Date of Lecture: 3 November 2022 About the Lecture: Randomised clinical trials are the cornerstone of evidence-based medicine. Professor Parmar will present how the design of the randomised clinical trial has been changed to improve outcomes for patients more quickly. This will be exemplified throughout by the STAMPEDE trial. The trial was started in 2005 when men with metastatic prostate cancer had an expected survival of approximately 3 years and no new effective treatments had been identified for over 40 years. Over the subsequent 17 years, through the STAMPEDE trial (together with other contemporaneous trials) the expected survival period has grown to 7 years, testing and introducing 4 new treatments for men with this disease. Professor Parmar will show how this model is being applied worldwide to many diseases including neurodegenerative diseases such as motor neuron disease, progressive multiple sclerosis, Parkinsons disease and dementia where the outcomes for patients are poor and little or no progress has been made for decades. About the Speaker: Max Parmar is a Professor of Medical Statistics and Epidemiology and Director of both the MRC Clinical Trials Unit at UCL and the Institute of Clinical Trials and Methodology at University College London.

Ass.-Prof. PD Mag. Dr. Peter Klimek vom Institut für Wissenschaft Komplexer Systeme (Center for Medical Statistics, Informatics and Intelligent Systems) an der MedUni Wien erklärt uns die Hintergründe und die Komplexität multipler Einflüsse auf die Lebensmittelversorgungssicherheit Österreichs. Komplexe Vorgänge vom Österreichischen Wissenschaftlers des Jahres 2021 verständlich und spannend in einem auch humorvollen Gespräch präsentiert Follow twitter.com/CSHVienna

Johanna is a statistician working in multi-drug resistant tuberculosis at UCL, London's leading multidisciplinary university currently ranked joint 7th in the QS World University Rankings. An Inglemoor High School graduate, she also has a BS in Mathematics from Western Washington University, certificate from the University of Washington in Statistical Analysis and a Masters in Medical Statistics from the London School of Hygiene and Tropical Medicine. R Programming courses on CourseraHost: Kira DorrianProduced by the Northshore Schools Foundation, a Top-Rated “Great Nonprofits” award-recipient, “Guidestar” Gold Participant, and Best of a “Best of Northshore” nonprofit.Thank you, supporters! DonateContact us: podcast@nsdfoundation.orgFollow us on:InstagramFacebookSkills 4 Life FacebookTwitterLinked In

This podcast is all about MMST (Master in Medical Science and technology) Programme of IIT, Kharagpur, India. Post MBBS a lot of graduates are interested in exploring technology driven medical career, this course is somewhat in that direction. Dr.Hara prasad speaks to one of his friends DrLokesh about this course and tries to dissect the whole course. Dr Lokesh Rajagopal(aka Dr.Loki) from Tamil Nadu finished his MBBS in 2015. Post that he has couple of years of clinical experience as a resident doctor before joining MMST programme at IIT-KHARAGPUR. In case you want to connect with him, reachout via linkedin. LINKEDIN ID of Dr.LOKI - https://www.linkedin.com/in/drlokeshrajagopal. The MMST program offered by the School is the only comprehensive physician-scientist training program in India which aims to bridge the gap that has historically separated biological sciences from engineering and physical sciences. The major benefit of this course is that it creates well equipped and highly skilled medical professionals who are capable of handling advanced technology in the field of medical sciences. It provides training for state-of-the-art medical research in frontier areas of Medical Imaging, Molecular Imaging and Image Analysis, Biomaterials and Implants, Biophysics, Medical Statistics, Telemedicine, Biomedical Instrumentation, Early Detection of Cancer, Immuno-technology, and the like. The MMST program is unique in the way that its the only comprehensive physician-scientist training program in India which aims to bridge the gap between biological sciences, engineering and physical sciences. An assistantship of Rs.25, 000/ per month is given to all the eligible students. The admission to MMST Programme is offered to students each year on the basis of an entrance examination conducted all over the country. As the School of Medical Sciences and Technology IIT Kharagpur has collaboration with top hospitals and research centers all over the country, it is an added advantage for the students associated with the institute. Some of the areas identified for teaching and R&D activities of the School are: Medical Imaging & Image Analysis Telemedicine & Tele Surgery Reproductive Health Healthcare Information Management System Preventive & Promotive Health Care System Bio-markers and their application in Oncology Tissue Engineering BioMaterials Bio - MEMS in Medicine Bio -MEMS & Sensors Wound Healing Research Herbal Medicine Instrumentation, Rehabilitation Engineering

Medical statistics might be being manipulated by the Biden Administration. AZ State Senator discusses that notion plus her endorsement from Donald Trump at his event in Florence, AZ.

A transcript for this episode can be found online, here. Host: Bekah Walker (Wellbeing Adviser)Staff: Amanda Lee (Chair in Medical Statistics & Director IAHS)Student: Megan Donoher (4th Year English), Benjamin Cramer (PhD in Music Composition), and Lucy Koster (PRG Student) Key themes explored: 1.       Imposture syndrome and who it affects2.       Where does imposture syndrome come from3.       Dealing with imposture syndrome and overcome it Resources: BeWell Have you experienced "Imposter syndrome"? Imposter Syndrome (kateatkin.com)

Dr. Miguel Hernán is a professor of biostatistics and epidemiology at the Harvard T.H. Chan School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. M.A. Hernán. Methods of Public Health Research — Strengthening Causal Inference from Observational Data. N Engl J Med 2021;385:1345-1348.

Professor Deborah Ashby, President of the RSS, gives the 2020 Florence Nightingale lecture. Florence Nightingale, best known as the Lady with the Lamp, is recognised as a pioneering and passionate statistician. She was also passionate about education, having argued successfully with her parents to be allowed to study mathematics, and later nursing, herself. More widely, she offered opinions on the education of children, soldiers, army doctors, and nurses, as well as railing against the ‘enforced idleness’ of women. A particular concern was the lack of statistical literacy among politicians. As we celebrate the bicentenary of her birth, the need for education in statistical and data skills shows no signs of abating. What advice would Florence Nightingale offer were she here today? The Lecture was followed by a Panel Session with Professor Deborah Ashby, Professor David Cox and Professor David Spiegelhalter. The Panel was chaired by Professor Jennifer Rogers about the role of statistics in society. Deborah Ashby is Director of the School of Public Health at Imperial College London where she holds the Chair in Medical Statistics and Clinical Trials, and was Founding Co-Director of Imperial Clinical Trials Unit. She is a Chartered Statistician and her research interests are in clinical trials, risk-benefit decision making for medicines, and the utility of Bayesian approaches in these areas. She has sat on the UK Commission on Human Medicines and acts as adviser to the European Medicines Agency. Deborah was awarded the OBE for services to medicine in 2009, appointed an NIHR Senior Investigator in 2010, and elected a Fellow of the Academy of Medical Sciences in 2012. She is currently President of the Royal Statistical Society.

Professor Deborah Ashby, President of the RSS, gives the 2020 Florence Nightingale lecture. Florence Nightingale, best known as the Lady with the Lamp, is recognised as a pioneering and passionate statistician. She was also passionate about education, having argued successfully with her parents to be allowed to study mathematics, and later nursing, herself. More widely, she offered opinions on the education of children, soldiers, army doctors, and nurses, as well as railing against the ‘enforced idleness’ of women. A particular concern was the lack of statistical literacy among politicians. As we celebrate the bicentenary of her birth, the need for education in statistical and data skills shows no signs of abating. What advice would Florence Nightingale offer were she here today? The Lecture was followed by a Panel Session with Professor Deborah Ashby, Professor David Cox and Professor David Spiegelhalter. The Panel was chaired by Professor Jennifer Rogers about the role of statistics in society. Deborah Ashby is Director of the School of Public Health at Imperial College London where she holds the Chair in Medical Statistics and Clinical Trials, and was Founding Co-Director of Imperial Clinical Trials Unit. She is a Chartered Statistician and her research interests are in clinical trials, risk-benefit decision making for medicines, and the utility of Bayesian approaches in these areas. She has sat on the UK Commission on Human Medicines and acts as adviser to the European Medicines Agency. Deborah was awarded the OBE for services to medicine in 2009, appointed an NIHR Senior Investigator in 2010, and elected a Fellow of the Academy of Medical Sciences in 2012. She is currently President of the Royal Statistical Society.

After patients get over the initial shock of learning about their parotid tumor diagnosis, they often wonder what causes these tumors to develop, and how common it is to have a parotid tumor.  In this episode, we will be discussing parotid tumor medical statistics, and the potential causes of these tumors with Dr. Kerry D. Olsen ; a parotid tumor expert with over 40 years of experience. Dr. Olsen recently retired from the Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota and currently serves as a Director and parotid tumor expert advisor for the Parotid Patient Project. Dr. Olsen has provided  parotid patients with exceptional care over the years, and he is here to answer these important questions for patients. Are you ready to learn? This episode is for you.Key Talking Points of the Episode:·       The incidence rate of parotid tumors for adults·       The incidence rate of parotid tumors for children·       The potential causes of parotid tumors·       Genetic links and parotid tumors·       Relationship between dental x-rays and parotid tumors·       Parotid tumors and cell phone usage·       Viruses and parotid tumors·       The connection between malignant parotid tumors and other types of cancersKey Quotes from the Episode:“The statistics are not as easy to find as one would think because a lot of times some statistics in certain areas are only recorded as salivary gland tumors, some as parotid tumors, and some as benign or malignant, and a lot of times they fail to take into consideration many other parotid diseases.” “So, at a minimum, 6 out every 100,000 has a parotid tumor; about five of those are going to be benign; 1 out of the 6 is going to be malignant, but there are many other patients that have parotid problems or pathology.”“Trying to find associations, causative factors with salivary tumors is very, very challenging because they are not common. They are rare, and most institutions do not have a lot of experience with them.”“It takes really diligent work and care to try to establish large databases, and that's why a project like the patient parotid project is so important because that has the capability to bring people together to establish large databases where people are willing to share some of their data to try to look for some of these associations. Is there causal factors that we can find with certain types of tumors that we didn't recognize before?”"I think the things that I tell people is it is very unlikely that they did anything to cause their tumor.” Connect with Us:·        Parotid Patient Project·        Facebook·        Instagram·        Twitter·        Email: podcast@parotidpatientproject.org Don't forget to like and subscribe to the podcast to stay fully up to date!  As always, know that you are not alone in this journey. 

Dr. Caroline Buckee is the associate director of the Center for Communicable Disease Dynamics at the Harvard T.H. Chan School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. I. Holmdahl and C. Buckee. Wrong but Useful — What Covid-19 Epidemiologic Models Can and Cannot Tell Us. N Engl J Med 2020;383:303-305. E.C. Schneider. Failing the Test — The Tragic Data Gap Undermining the U.S. Pandemic Response. N Engl J Med 2020;383:299-302.

Gemma Hodgson has an MSc in Medical Statistics and worked in the pharmaceutical industry as a statistician for over 15 years. Gemma now runs Qi Statistics Ltd, and gives statistical training and consultancy advice to a wide variety of customers in sensory and consumer science, pharmaceuticals, and manufacturing. Gemma is known for her approachable attitude and skills at converting complex concepts into ideas that can be applied in practice.     LinkedIn: https://www.linkedin.com/in/gemmahodgsonstats/   Qi Statistics Ltd: https://www.qistatistics.co.uk/   Qi Statistics on LinkedIn: https://www.linkedin.com/company/qi-statistics/   To learn more about Aigora, please visit www.aigora.com  

When Sir Richard Peto began work with the late Richard Doll fifty years ago, the UK had the worst death rates from smoking in the world. Smoking was the cause of more than half of all premature deaths of British men. The fact that this country now boasts the biggest decrease in tobacco-linked mortality is in no doubt partly due to Doll and Peto's thirty year collaboration. Professor of Medical Statistics and Epidemiology at the University of Oxford and until last year co-director of the Clinical Trial Service Unit with Professor Sir Rory Collins, Richard Peto pioneered "big data", setting up enormous randomised clinical trials and then, in a novel approach, combining results in what became known as meta-analyses, amassing unequivocal evidence about how early death could be avoided. He showed how asprin could prevent heart attacks and how the oestrogen-blocking drug tamoxifen really did affect survival rates for breast cancer patients. Results on paper saves lives in the real world, he says, and he's famous for catchphrases like: "death in old age is inevitable, but death before old age is not" and "you can avoid more deaths by a moderate reduction of a big cause, than by a big reduction in a small cause" as well as "take the big numbers seriously". One of the world's leading epidemiologists, Richard Peto's landmark study with Alan Lopez at the World Health Organisation predicted that a billion people would die from diseases associated with tobacco this century, compared to a hundred million killed by tobacco in the 20th century. The chilling message galvanised governments around the world to adopt anti-smoking policies. And Professor Peto's studies about smoking cessation ("smoking kills, stopping works") provided the public health evidence needed to encourage smokers that, however long they had smoked for, it was always worth quitting.

This talk was delivered by Martin Bland. Martin Bland joined the University of York as Professor of Health Statistics in 2003, retiring and becoming Emeritus Professor in 2015. Earlier posts were at St. George's and St. Thomas's Hospital Medical Schools and in industry with ICI, working on agricultural experiments. He is the author of An Introduction to Medical Statistics, now in its fourth edition, and co-author of Statistical Questions in Evidence-based Medicine, both Oxford University Press, 303 refereed journal articles, and, with the late Prof. Doug Altman, the Statistics Notes series in the British Medical Journal. He and Doug Altman also invented the limits of agreement method for comparing methods of measurement, which led to the most highly cited papers in six different journals and one of the top 30 most highly cited papers over all fields. This is an account of a little research study which I carried out, using myself as the only research subject. I shall describe how I came to do it and some of the practical statistical problems which I encountered. These include serial P-values, the effect of other factors, and generalisability from a single subject.

This talk was delivered by Martin Bland. Martin Bland joined the University of York as Professor of Health Statistics in 2003, retiring and becoming Emeritus Professor in 2015. Earlier posts were at St. George's and St. Thomas's Hospital Medical Schools and in industry with ICI, working on agricultural experiments. He is the author of An Introduction to Medical Statistics, now in its fourth edition, and co-author of Statistical Questions in Evidence-based Medicine, both Oxford University Press, 303 refereed journal articles, and, with the late Prof. Doug Altman, the Statistics Notes series in the British Medical Journal. He and Doug Altman also invented the limits of agreement method for comparing methods of measurement, which led to the most highly cited papers in six different journals and one of the top 30 most highly cited papers over all fields. This is an account of a little research study which I carried out, using myself as the only research subject. I shall describe how I came to do it and some of the practical statistical problems which I encountered. These include serial P-values, the effect of other factors, and generalisability from a single subject.

This week I'm talking to Keeley Olivia, Keeley Olivia is a Female Sexuality Expert on a mission to Unleash the Female Orgasm of the World. She wrote a Masturbation Memoir - Unleashing the Female O - detailing her journey to discovering orgasm and delivered a TEDx talk - Masturbation is the New Meditation- where she offered new paradigm thinking on female sexuality and self pleasure. She is a Professionally trained Sex, Love, Relationship & Transformational Coach, and worked for a decade as an academic researcher & scientist at some of the world's highest rated research institutions. Keeley holds a first class Chemistry degree, studied Regenerative Medicine at postgraduate level and has a Masters degree in Medical Statistics. She is now bringing Anarchy to the UK via the Sexual Revolution! In this show we did a deep dive into all things self pleasure, the why, what and how! And how self pleasure links to other gorgeous topics such as body acceptance, sexuality and intimacy. This is one of those shows that I would love all women to listen to - it really is that important.

When Sir Richard Peto began work with the late Richard Doll fifty years ago, the UK had the worst death rates from smoking in the world. Smoking was the cause of more than half of all premature deaths of British men. The fact that this country now boasts the biggest decrease in tobacco-linked mortality is in no doubt partly due to Doll and Peto's thirty year collaboration. Professor of Medical Statistics and Epidemiology at the University of Oxford and until last year co-director of the Clinical Trial Service Unit with Professor Sir Rory Collins, Richard Peto pioneered "big data", setting up enormous randomised clinical trials and then, in a novel approach, combining results in what became known as meta-analyses, amassing unequivocal evidence about how early death could be avoided. He showed how asprin could prevent heart attacks and how the oestrogen-blocking drug tamoxifen really did affect survival rates for breast cancer patients. Results on paper saves lives in the real world, he says, and he's famous for catchphrases like: "death in old age is inevitable, but death before old age is not" and "you can avoid more deaths by a moderate reduction of a big cause, than by a big reduction in a small cause" as well as "take the big numbers seriously". One of the world's leading epidemiologists, Richard Peto's landmark study with Alan Lopez at the World Health Organisation predicted that a billion people would die from diseases associated with tobacco this century, compared to a hundred million killed by tobacco in the 20th century. The chilling message galvanised governments around the world to adopt anti-smoking policies. And Professor Peto's studies about smoking cessation ("smoking kills, stopping works") provided the public health evidence needed to encourage smokers that, however long they had smoked for, it was always worth quitting. Producer: Fiona Hill

This Christmas Day 2018 Podcast features a conversation with Keeley Olivia (keeleyolivia.com), a sex and relationships expert whose TEDx talk 'Masturbation is the New Meditation' has amassed around half a million views in only a few weeks! During the conversation, we cover themes in human sexuality and sexual behaviour, shame and honesty, and the need to change our social and educational attitude towards sex and relationships. Also, Keeley shares what it was like to talk about her 'masturbation memoir' with the world. Keeley Olivia is a professionally trained transformational, and sex, love and relationship coach as well as an academic researcher and scientist with almost a decade of experience. She holds a first class degree in Chemistry, studied Regenerative Medicine at postgraduate level and has a Masters degree in Medical Statistics. She is now bringing Anarchy to the UK via the Sexual Revolution! Please support us through joining the Facebook group, following and interacting with @CircularityORG on Twitter and IG, and @CircularityPOD also on Twitter. Visit the website at circularity.org and explore the materials there, and definitely watch our TEDx Talk! Consider supporting us by becoming a patron for Circularity at patreon.com/circularity.

Andrew Nunn joined the MRC’s Tuberculosis & Chest Diseases Unit as a statistician in 1966. During the next 20 years he was directly involved in the design, conduct and analysis of the programme of trials conducted under the leadership of Professors Wallace Fox and Denny Mitchison in East Africa, Hong Kong and Singapore which led to the worldwide adoption of short course chemotherapy for tuberculosis. Following the closure of that unit he joined the MRC’s Uganda AIDS Programme which researched the dynamics of the HIV epidemic in a rural African environment. On his return to the UK he became head of the Division Without Portfolio within the newly formed MRC Clinical Trials Unit with responsibility for developing trials in neglected areas. Andrew is Co-Chief Investigator of STREAM, the first randomised controlled-trial of a treatment regimen for multi-drug resistant TB. In the context of treatment guidelines based on ‘very low quality’ evidence, Andrew designed STREAM to generate gold-standard evidence on the safety and efficacy of the promising 9-month short-course regimen previously evaluated only in observational studies. The trial has subsequently been adapted to test a bedaquiline-containing oral regimen.

Andrew Nunn joined the MRC’s Tuberculosis & Chest Diseases Unit as a statistician in 1966. During the next 20 years he was directly involved in the design, conduct and analysis of the programme of trials conducted under the leadership of Professors Wallace Fox and Denny Mitchison in East Africa, Hong Kong and Singapore which led to the worldwide adoption of short course chemotherapy for tuberculosis. Following the closure of that unit he joined the MRC’s Uganda AIDS Programme which researched the dynamics of the HIV epidemic in a rural African environment. On his return to the UK he became head of the Division Without Portfolio within the newly formed MRC Clinical Trials Unit with responsibility for developing trials in neglected areas. Andrew is Co-Chief Investigator of STREAM, the first randomised controlled-trial of a treatment regimen for multi-drug resistant TB. In the context of treatment guidelines based on ‘very low quality’ evidence, Andrew designed STREAM to generate gold-standard evidence on the safety and efficacy of the promising 9-month short-course regimen previously evaluated only in observational studies. The trial has subsequently been adapted to test a bedaquiline-containing oral regimen.

Prof. Janet Peacock and Medical Statistics by NIHR

In this episode Keeley Olivia and I discuss sexual stereotypes, what to do when you feel the best sex of your life is behind you, what happens when women awaken to their bodies, and their orgasmic potential, and how to tap into total self acceptance. Keeley is a Sexuality and Relationship Expert and Certified Jade Egg Practitioner trained at The Tantric Institute of Integrated Sexuality founded by Layla Martin - one of the worlds most highly regarded and influential Sexuality Teachers alive today. She has spent over 10 years studying the art and science of Yoga and over 5 years studying Tantra, and is a highly trained and certified Transformational and Holistic Sexuality Coach.  Keeley combines her World-Class Training in Sexuality with 10 years experience working as a Professional Scientist and Research Academic with a First Class Bachelors degree in Chemistry, two Masters degrees (in Regenerative Medicine and Medical Statistics), and several Published Research Papers in the fields of Social, Medical and Public Health. You can rest assured that she will deliver no other than the highest standards of intelligence, integrity and practicality in service of your sexual and relational awakening.  Her mission is orgasmic world peace and she looks forward to seeing you there.  Find more about Keely and download her free book Unleashing the Female O www.bit.ly/femaleo and www.keeleyolivia.com

A podcast about a song about vaping based on the latest evidence from research from Dr Jamie Hartmann-Boyce at the University of Oxford Vaping has exploded onto the scene as an new technology for smoking. Whilst there's a huge amount of debate about vaping in general there is one thing we know: for those already smoking, switching to vaping is much better for you. This interview explores the research behind how we know this, and features the song, 'The Great Vape Debate'. The song was written by Jonny Berliner in collaboration with Dr Jamie Hartmann-Boyce who works in the Cochrane Tobacco Addiction Group in the Nuffield Department of Primary Care Health Sciences at the University of Oxford. You can explore the research at http://www.cochranelibrary.com/ and on Twitter @CochraneTAG. views stated and expressed in this song are entirely personal, and do not represent any official views or opinions of Cochrane.

Professor Carl Heneghan, Director of the Centre for Evidence-Based Medicine, speaks to Professor Sir David Spiegelhalter, Winton Professor of the Public Understanding of Risk at the University of Cambridge, about the importance of medical statistics.

Funnel plots are a central part of how the results of a meta analysis are presented. Learn what they are, what they mean and how to interpret them with Rob Radcliffe.

If you think that relative risk is worrying that Uncle Brian will start dancing at the wedding, then you need to watch this podcast by Rob Radcliffe. Rob explains and helps you define, recognise and avoid bias in trials and explains what relative risk and odds ratio are, and the difference between them. Essential listening if you want to be able to read and interpret others research, or design your own. Also very useful for those pesky exams and academic stations in selection processes. Rob Radliffe is a former maths teacher and current Urology Registrar in the East Midlands, UK.

Listen to Professor Orlando Mayoral talking about the extraordinary research he’s carried out on patients that had a knee arthroplasty procedure & how he tested the ability of Dry Needling to help these patients.We’ll dissect his research & break it down so we can all understand what it means for us as Dry Needling Therapists.Have you ever read a research paper or even a conclusion & still couldn’t work out whether the findings were relevant, important or even valid? Do you know what these terms mean: P value, standard deviation, confidence intervals, sensitivity, specificity, mean, mode &medians? If you don’t, you should. Any practitioner who wants to provide the best care possible to their patients MUST know how to read research papers & be able to understand the relevance to their practice.Dr Graham Taylor is going to make things really easy for us when trying to understand Medical Statistics. He will only speak in PLAIN ENGLISH. So, you’ll walk away with a good basic understanding of what’s important to know as a clinician & what should be left to the experts.

There are 2 test I can use to see if this patient has got cancer, which one is best? How do I know? How can I compare them?? These were just some of the thoughts going through the candidates mind as his stared at the paper in the academic viva in national selection! If only they'd listened to Rob Radcliffe, who is on hand to explain how you do just that using receiver operating characteristic curves, a really easy way to compare the performance of tests and probably the most useful to medicine thing that had its origin in WW II radar technology. Starting with a review of sensitivity and specificity (see http://schoolofsurgery.podomatic.com/entry/2014-05-02T00_31_49-07_00 for full revision) Rob shows how sensitivity and specificity vary with the cut off point for a test and demonstrates the best test you can design and the worst and shows you how to construct a ROC curve. Real life examples are discussed and how to compare test visually from their curves, and how this can be qualified (and so compared statistically to find the best performing test) using Area Under the Curve (AUC) is also explained. This is the clearest explanation you will find anywhere for this commonly used comparison (check out the Wikipedia page on this if you don't believe me). Is is essential to know as ROC curve feature often in medical literature and often in exams and academic interviews. Rob Radcliffe was a maths teacher in a former life and is now a trainee in Urology in the East Midlands, UK

How confident are you with confidence intervals? Perhaps not 95%.... In this podcast Rob Radcliffe explains what confidence intervals are, how to interpret them and how they provide a deeper understanding of data and the p value. Essential viewing for any student, trainee or consultant/attending reading a scientific paper and wanting to interpret the data correctly. Rob Radcliffe is a former maths teacher and is now a trainee in Urology in the East Midlands, UK

The interview was going well until at the academic station the interviewer asked: "Can you tell me what you understand by the power of a trial and what was the sensitivity of the test used in this study?" A bead of sweat appeared on the forehead of the applicant. If only she'd listened to Rob Radcliffe explaining binary tests, sensitivity, specificity, positive predictive value, negative predictive value and power she wouldn't have to come back next year and try again! These terms are in regular use in medical studies, tests and trials. They are often very poorly explained and even less well understood. Rob takes you though binary tests and power in a step by step manner which is easy to understand. You will not find this more clearly explained anywhere else. This video podcast will help you to understand and critique research and help you to design your own studies. Watch this and you will need all you ever need to know. Rob Radcliffe is a former teacher of mathematics and is now a trainee in the School of Surgery in the East Midlands, UK.

"Why would you do a t-test on these data and what is it?" asked the interviewer in a national selection interview. "Errrrrrr...." replied the trainee surgeon who was beginning to think they wished they had watched the video podcast on hypothesis testing using this test. Oh well - he thought, I can always try again next year.... In the third podcast on hypothesis testing, Rob Radcliffe tells you all about t-test, what t is, how you use the t-test and what it actually means. This podcast is the clearest explanation of the most commonly used test in medical statistics you will find anywhere. Watch it and know all you will ever need to know

What's a population? Easy question? Or not? What's a representative sample? What's a random sample from the population and how do you decide if the set of data you have is the same or different from your population. How many samples do you need to take to be representative of the whole population? Rob Radcliffe explains these concepts and much more, passing through central limit theorem - the very core of medical statistics - to explain all of these easy sounding but difficult concepts in a clear and easy to understand video podcast. Biased and unbiased estimators, sampling distribution of the mean, the difference between standard deviation and standard error and the key principles underlying the statistical tests we all use all the time are explained. See this podcast and you will understand what you are doing when you are looking at the results of a paper, be able to answer questions in exams with more confidence and be on the way to designing your own study and the analysis of the data. Essential viewing for medical students, core trainees (junior residents) and higher trainees (senior residents) as exams approach, and also fro anyone starting or in the middle of a research project. There are lots of books on statistics out there, but none as clear as these vodcasts. Next time: statistical testing

Statistics is a bit of a mystery to most of us. Help is here from former maths teacher and current surgical trainee, Rob Radcliffe. In the third in this series explaining medical statistics, Rob explains hypothesis testing. This is fundamental to just about all we do when cam paring data in trials. The null hypothesis is explained and when it is safe to reject it (how to tell if 2 distributions are the same or different and by how much). This podcast also makes it clear where the "magic" p

Do you have an average number of legs? Most likely you have slightly more than the mean number of lower limbs if you think about it. It is important to be able to describe data properly so that we convey the correct and accurate meaning. In his second podcast on medical statistics, Rob Radcliffe takes us through descriptive statistics, central tendency and normal distribution in an accessible and painless fashion. Easy to understand explanations are supplemented with diagrams and charts so that you will know how to apply descriptive statistics to data by the end of the podcast and also how to interpret others data when you see it in publications. This podcast gives you an essential basis in medical statistics which you will need to understand before moving onto the the next in the series, which will explain hypothesis testing. It is essential viewing for all medical students, trainees in surgery and even senior surgeons who want an easy to understand refresher and were afraid to ask. A knowledge of statistics and competency in data interpretation are now integral parts of many interview, exam and selection processes. Rob Radcliffe is a former mathematics teacher and is currently a trainee in surgery in the East Midlands School of Surgery, UK

In the first of his series on medical statistics, Rob Radcliffe, maths graduate, former maths teacher and current trainee in surgery in East Midlands School of Surgery, talks us through a way to clearly formulate clinical questions. Correct formulation of these questions is fundamental to research, the correct use of statistics in clinical settings and will help you to read, interpret and critique a scientific paper. Rob describes, using an example from his own practice, the PICO method to help with logical formulation of clinical questions each time we want to ask them. This podcast is aimed at medical students, core trainees in surgery (junior residents), trainees in higher surgical training, consultants and anyone interested in research, reading, writing or reviewing an academic paper. This, and the rest of the series, will be especially useful to trainees coming up to interview or examination where there will be an academic component with an expectation of a working knowledge of statistics. The next part of the series will cover descriptive statistics

Dr Carl Heneghan talks to Rafael Perera about medical statistics and gives an introduction to the subject.

Sir Richard Peto, GTC Fellow, Professor of Medical Statistics and Epidemiology at the University of Oxford, gives the annual McGovern Lecture. This year's annual McGovern Lecture in the history of medicine sets Sir Richard Doll's contribution to our understanding of disease - especially his discovery of the link between tobacco and lung cancer - in the historical context of the span of the twentieth century.

Sir Richard Peto, Professor of Medical Statistics and Epidemiology, delivers a talk at the inaugural Oxford-India Day, held at the Saïd Business School, University of Oxford on 17 June 2011.

The first report reviews medical statistics commonly used in "risk" shared by physicians when patients are making an informed decision. The second report reviews a new program (Physician Orders for Life-Sustaining Treatment or POLST) aimed at refining end of life decisions.