Podcasts about progressive ms

Immunic Inc (NASDAQ:IMUX, FRA:10VA) CEO Erik Lundgren spoke with Proactive's Stephen Gunnion about the company's second-quarter results, its leadership transition and the milestones set to shape the next phase of its multiple sclerosis (MS) programme. Lundgren explained why he joined Immunic, pointing to the potential of lead candidate vidofludimus calcium and the chance to lead the business into two pivotal Phase 3 readouts. Both the ENSURE-1 and ENSURE-2 Phase 3 studies in relapsing MS are fully enrolled and on track to report results by year-end, with the company already engaging health authorities ahead of the data and any subsequent regulatory filing. The interview also covered Immunic's strengthened leadership team, including new chairman Michael Bonney, board member Jon Congleton and chief medical officer Dr Michael A. Panzara - part of a push to build deep MS expertise to support the company's long-term strategy. Lundgren flagged another key goal: launching a Phase 3 study in progressive MS before year-end. "The other big milestone we're really focused on is initiating a Progressive MS study by the end of this year," he said, adding that the programme could widen the market opportunity for vidofludimus calcium and address a significant area of unmet need. On financials, Immunic ended Q2 with around $155 million in cash, providing runway into late next year, with further funding potentially available through conversion of pre-funded warrants following positive clinical data. For more interviews with leading healthcare and biotechnology companies, visit the Proactive YouTube channel. Don't forget to like this video, subscribe to the channel and enable notifications so you never miss future content. Read Proactive's Editorial Policy here: https://www.proactiveinvestors.co.uk/pages/editorialPolicy #Immunic #MultipleSclerosis #MS #Biotech #Biotechnology #ClinicalTrials #Phase3 #VidofludimusCalcium #Healthcare #DrugDevelopment #Nasdaq #Investing #Biopharma #ProactiveInvestors

Send us Fan MailThis week on Just MS News, we take a closer look at three important stories from the multiple sclerosis community.First, new research in JAMA Neurology strengthens the evidence around GFAP, a blood biomarker that may help researchers track progression independent of relapse activity, or PIRA. The study included more than 2,300 people with MS and over 18,000 blood measurements.That story also connects with a small randomized study of high-dose N-acetyl cysteine, or NAC, in progressive MS. Participants received 1,250 mg three times daily for four weeks, and researchers observed a significant difference in GFAP levels compared with placebo. The study was very small and does not show that NAC slows MS progression, but a larger trial is already underway.Next, we review a systematic review of exercise in people with severe MS disability. What can exercise still improve when walking is limited or disability has progressed, and why are nonambulatory people still so underrepresented in exercise research?Finally, Christina Applegate is reportedly back home and doing very well following a months-long hospitalization. Applegate has been living publicly with MS since announcing her diagnosis in 2021.Just MS News looks beyond the headline to explain what the research actually found, what remains uncertain, and why it may matter to people living with MS.Sources include JAMA Neurology, Multiple Sclerosis Journal, Multiple Sclerosis and Related Disorders, University of Basel, UCSF, Neurology Advisor, and PEOPLE.Learn more and follow the latest MS news at:www.justmultiplesclerosis.comThis content is for news and educational purposes and is not medical advice.The Just MS (Multiple Sclerosis) Show, w host Justin Loizos, is a podcast that connects, educates and tries to uplift others living with multiple sclerosis. It provides real-life stories, interviews, and information about DMTs (disease modification therapies) and updates on research developments.www.justmultiplesclerosis.com

Send us Fan MailThis Week on Just MS NewsThis week, we look at three important stories affecting the MS community.Researchers in Australia are using lab grown “mini brains” to investigate how damaged myelin might one day be repaired. Sheffield Teaching Hospitals has also treated its first MS participant with experimental CAR T cell therapy, an approach researchers have been watching for years.We also examine a revised Cleveland Clinic protocol designed to help MS clinicians respond more confidently when a patient reports suicidal thoughts.The episode finishes with several additional stories worth checking out, including treatment discontinuation in older adults, EBV vaccine and T cell research, MS treatment sequencing, OCT in diagnosis, and the need for better pain care.Featured storiesResearchers use lab grown mini brains to study MS repairSheffield treats its first MS participant with CAR T cell therapyCleveland Clinic revises its suicidal ideation protocol for MS careMore stories worth checking outStopping disease modifying therapies in older, stable patientsEBV vaccine and T cell trials in MSFramework for sequencing MS treatmentsOCT and the updated McDonald diagnostic criteriaWhy MS pain needs more attentionVisit Just Multiple Sclerosis for the always open MS news stream, past weekly editions, community updates, and Sudoku Omega, a free sudoku game I built to help you slow down, focus, and relax.Follow Just Multiple Sclerosis on Instagram and Facebook for weekly clips, updates, and community highlights.Mental Health and Crisis SupportUnited States: Call or text 988 to reach the 988 Suicide & Crisis Lifeline. Free, confidential support is available 24 hours a day across the United States and its territories. Canada: Call or text 988 to reach the 9-8-8 Suicide Crisis Helpline. Support is available nationwide, 24 hours a day, in English and French. Visit 988.ca.Other countries: Find verified crisis and emotional-support services in your country through Find A Helpline or Befrienders Worldwide. If someone is in immediate danger, contact local emergency services.The Just MS (Multiple Sclerosis) Show, w host Justin Loizos, is a podcast that connects, educates and tries to uplift others living with multiple sclerosis. It provides real-life stories, interviews, and information about DMTs (disease modification therapies) and updates on research developments.www.justmultiplesclerosis.com

Welcome to IDEA Collider with your host, Rick Ritacco. In this episode, we sit down with Jason Tardio, President and COO of Immunic, to discuss the rapidly evolving landscape of Multiple Sclerosis (MS) treatment. For 30 years, MS therapies have primarily focused on controlling inflammation and visible relapses. Jason argues it's time to look deeper and address the ongoing neurodegeneration driving long-term disability, known as Progression Independent of Relapse Activity (PIRA). We explore Immunic's investigational therapy, vidofludimus calcium, and its unique dual-mechanism approach: acting as a DHODH inhibitor for anti-inflammatory benefits while also activating the Nurr1 nuclear receptor to potentially provide direct neuroprotection. Jason shares insights from the EMPHASIS and CALIBER clinical trials, discusses why the industry needs safer immunomodulators rather than just broad immunosuppressants (especially as the MS population ages), and shares a fascinating biological link between MS remission during pregnancy and Nurr1 levels. Tune in to hear what the next 10 to 15 years hold for MS patients, including the ultimate goals of halting progression entirely and achieving remyelination.   Episode Timestamps 00:00:00 - Introduction: Meet Jason Tardio, President and COO of Immunic. 00:02:01 - The Evolution of MS Treatment: Transitioning from purely anti-inflammatory approaches to addressing underlying neurodegeneration. 00:04:29 - What is PIRA?: Understanding Progression Independent of Relapse Activity and why patients still accumulate disability. 00:10:30 - The Dual-Mechanism Approach: How vidofludimus calcium combines DHODH inhibition with Nurr1 activation. 00:13:33 - The Power of Nurr1: Exploring the target's role in neuronal survival and the fascinating biological link to pregnancy in MS patients. 00:18:14 - Clinical Validation: Analyzing data from the EMPHASIS (relapsing MS) and CALIBER (progressive MS) trials. 00:27:42 - Standing Out in a Crowded Market: Why safety, tolerability, and avoiding broad immunosuppression matter, especially for aging MS patients facing immunosenescence. 00:36:08 - The Next 10 Years: Moving towards halting progression, potential remyelination, and the need to reclassify MS beyond relapsing and progressive labels.   Don't forget to Like, Share, Subscribe, Rate, and Review!   Keep up with Jason Tardio; LinkedIn: https://www.linkedin.com/in/jason-tardio/   Keep up with Rick Ritacco: LinkedIn: https://www.linkedin.com/in/rritacco/   Follow IDEA Pharma On; Website: https://www.ideapharma.com/   Listen to more fantastic podcast episodes: https://ideacollider.simplecast.com/    

Send us Fan MailThis week on the Just MS Show, we look at five important multiple sclerosis stories.Researchers used artificial intelligence to identify gray matter lesions that can be difficult to see on standard MRI scans. We also examine a head-to-head trial comparing rituximab with Ocrevus in newly diagnosed relapsing MS.Other stories include the completion of enrollment in a nasal foralumab trial for non-active secondary progressive MS, early research into how myelin damage may affect brain activity during sleep, and a $500,000 gift supporting MS research from Las Vegas Raiders quarterback Fernando Mendoza and his family.The Just MS Show delivers calm, clear and accessible MS news without hype or information overload.Show NotesAI reveals previously hidden gray matter lesions in MSResearchers developed an artificial intelligence method that can identify cortical lesions that are often difficult to see on conventional MRI scans.Read the article from News-MedicalRituximab compares closely with Ocrevus in early relapsing MS trialThe OVERLORD-MS trial compared rituximab with Ocrevus in people with newly diagnosed relapsing MS and found rituximab was noninferior for preventing new or enlarging MRI lesions during the study period.Read the article from Conexiant NeurologyFinal participant begins treatment in nasal foralumab trial for non-active SPMSEnrollment is complete in the Phase 2 INFORM-MS trial studying intranasal foralumab in people with non-active secondary progressive MS. Full safety and effectiveness results have not yet been released.Read the article from NR TimesMyelin damage may alter brain rhythms during sleepEarly research suggests that damaged myelin may affect electrical brain activity during sleep. The strongest evidence currently comes from animal research, with further human studies still needed.Read the article from News-MedicalMendoza family presents $500,000 gift for MS researchLas Vegas Raiders quarterback Fernando Mendoza and his family formally presented a $500,000 gift supporting MS research at the University of Miami in honour of his mother, Elsa, who lives with MS.Read the article from 8 News NOWLinksJust MS News:https://www.justmultiplesclerosis.comPodcast page:https://www.justmultiplesclerosis.com/podcastWeekly news archive:https://www.justmultiplesclerosis.com/archiveThe Just MS (Multiple Sclerosis) Show, w host Justin Loizos, is a podcast that connects, educates and tries to uplift others living with multiple sclerosis. It provides real-life stories, interviews, and information about DMTs (disease modification therapies) and updates on research developments.www.justmultiplesclerosis.com

Send us Fan MailThis week's Just MS News starts with two stories from the same MS brain-donor study, looking at why progression can differ so much from person to person. We also cover MS Copilot and digital disability monitoring, research into fat-filled immune cells called foamy microglia, an experimental brain implant for speech loss, and Spain's “Get Wet for MS” campaign supporting neurorehabilitation and research.As always, this update is designed to give the MS community one calm place to catch up on the week's most relevant news without hype or overload.Live article linksLarge multiple sclerosis brain cohort reveals biological differences linked to disease severity https://medicalxpress.com/news/2026-06-large-multiple-sclerosis-brain-cohort.htmlBrain Tissue Patterns and Genetics Drive MS Progression https://neurosciencenews.com/multiple-sclerosis-progression-genetics-30961/EAN 2026: MS Copilot shows promise in monitoring disability progression in MS https://www.clinicaltrialsarena.com/analyst-comment/ean-2026-ms-copilot-shows-promise-in-monitoring-disability-progression-in-ms/Fat-filled immune cells may help explain why some MS progresses faster https://www.diabetes.co.uk/news/2026/jul/fat-filled-immune-cells-may-help-explain-why-some-ms-progresses-faster.htmlNew brain implant could restore communication for people with speech loss https://www.news-medical.net/news/20260629/New-brain-implant-could-restore-communication-for-people-with-speech-loss.aspxPromote neurorehabilitation and research, challenges of “Mójate por la Esclerosis Múltiple” 2026 https://www.democrata.es/en/health/promote-neurorehabilitation-and-research-challenges-of-mojate-por-la-esclerosis-multiple-2026/The Just MS (Multiple Sclerosis) Show, w host Justin Loizos, is a podcast that connects, educates and tries to uplift others living with multiple sclerosis. It provides real-life stories, interviews, and information about DMTs (disease modification therapies) and updates on research developments.www.justmultiplesclerosis.com

Send us Fan MailThis week on Just MS News, we look at nine MS stories from the week of June 15–21, 2026.Topics include hidden cognitive symptoms, brain atrophy research, cognitive testing and daily life, accessible travel, progression independent of relapse activity, PFAS exposure, vaccine safety, mobility technology, and early repair-focused stem cell research.Just MS News is built to help the MS community cut through the noise and follow the stories that matter.Covered this week:UB research targets hidden symptoms of multiple sclerosis https://www.buffalo.edu/ubnow/stories/2026/06/benedict-hidden-symptoms-ms.htmlUntangling Brain Atrophy in MS https://www.nationalmssociety.org/news-and-magazine/momentum-magazine/research-and-science/untangling-brain-atrophy-in-msCan Cognitive Tests Predict Daily Life With MS? The Answer Is Yes, But Not Perfectly https://www.zmescience.com/science/news-science/can-cognitive-tests-predict-daily-life-with-ms-the-answer-is-yes-but-not-perfectly/10 MS Accessible Travel Planning Tips https://www.nationalmssociety.org/news-and-magazine/momentum-magazine/living-well/plan-an-accessible-escapeComorbidities for Predicting Progression Independent of Relapse Activity in Multiple Sclerosis Treated With B-Cell Depletion https://pubmed.ncbi.nlm.nih.gov/42226439/PFAS “forever chemicals” may be linked to multiple sclerosis, especially in women https://usrtk.org/healthwire/pfas-forever-chemicals-linked-to-multiple-sclerosis-especially-in-women/Measles, chickenpox vaccines not tied to relapse in people with multiple sclerosis https://www.cidrap.umn.edu/measles/measles-chickenpox-vaccines-not-tied-relapse-people-multiple-sclerosisParalyzed Minnesota man's invention aims to help people with mobility issues walk again https://www.cbsnews.com/minnesota/news/walkport-invention-mobility-issues/NewcelX Stem Cell Platform Strengthened by Peer-Reviewed AstroRx Study in Multiple Sclerosis https://www.tipranks.com/news/company-announcements/newcelx-stem-cell-platform-strengthened-by-peer-reviewed-astrorx-study-in-multiple-sclerosisOne week of MS news. One calm place.The Just MS (Multiple Sclerosis) Show, w host Justin Loizos, is a podcast that connects, educates and tries to uplift others living with multiple sclerosis. It provides real-life stories, interviews, and information about DMTs (disease modification therapies) and updates on research developments.www.justmultiplesclerosis.com

Today we welcome Dr. Daniel Vitt, CEO of Immunic Therapeutics. With World MS Day being tomorrow, the 30th of May, this is the perfect moment to focus on multiple sclerosis — a disease that affects nearly three million people worldwide and still leaves many patients searching for better options.In today's episode Daniel shares his own journey into biotechnology, walk us through what life with MS really looks like for patients, and explain the science behind Immunic's most advanced program, IMU-838. We discuss what makes Immunic's oral therapy different from today's treatments, uncover the latest data from the CALLIPER and ENSURE trials, and talk about what the future of MS care could look like.01:22 Meet Daniel Vitt04:54 Understanding multiple sclerosis07:53 Evolution of the MS treatment landscape12:08 Immunic's lead MS therapy explained22:57 World MS Day and what's next for ImmunicInterested in being a sponsor of an episode of our podcast? Discover how you can get involved here! Stay updated by subscribing to our newsletterTo dive deeper into the topic: 11 neuroscience biotech companies you should know aboutThe emergence of BTK inhibitors in multiple sclerosis treatment: Companies close in on approvalSix biotech companies advancing multiple sclerosis therapies

Tiziana Life Sciences CEO Ivor Elrifi joined Steve Darling from Proactive to announce that patient enrollment has been completed in the company's randomized, double-blind, placebo-controlled Phase 2 clinical trial evaluating intranasal foralumab in patients with non-active Secondary Progressive Multiple Sclerosis (na-SPMS). The company expects topline data from the study in the third quarter of 2026. In addition, findings from the trial are scheduled to be presented at the Joint Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) and ECTRIMS meeting in Toronto in October 2026. The trial represents the first Phase 2 placebo-controlled evaluation of intranasal foralumab and marks an important step in the development of what the company describes as a novel anti-CD3 monoclonal antibody platform targeting neurodegenerative and neuroinflammatory diseases. The multicenter study enrolled 48 participants across multiple leading U.S. sites, with patients receiving either intranasal foralumab or placebo over a 12-week treatment period. The study includes a broad range of assessments designed to evaluate both safety and efficacy, including PET imaging to examine microglial activation, MRI analysis, and comprehensive clinical evaluations. Patients who complete the blinded phase of the study will also have the opportunity to continue treatment in a six-month open-label extension phase designed to evaluate longer-term safety and sustained therapeutic benefit in the na-SPMS patient population. Management said completion of enrollment marks an important milestone in advancing the clinical program and reinforces the company's commitment to addressing significant unmet needs in progressive neurological disorders. The company believes the study could provide important insights into whether intranasal foralumab may help regulate immune system activity and address neuroinflammation, potentially opening a new treatment pathway for patients living with progressive multiple sclerosis. #proactiveinvestors #tizianalifescienceslts #nasdaq #tlsa #newceo #ivorelrifi #Foralumab #SPMS #Biotech #ClinicalTrials #Neuroimmunology #HealthcareInnovation #DrugDevelopment #MedTech #MultipleSclerosis #MSResearch #Biotech #ClinicalTrials #Neurology #Healthcare #DrugDevelopment #Pharma

Support the show and get 50% off MCT oil with free shipping—just leave us a review on iTunes and let us know!https://podcasts.apple.com/us/podcast/live-beyond-the-norms/id1714886566 A medical doctor gets an incurable diagnosis, lands in a wheelchair, and is told there's no hope. Instead of accepting her fate, she created a protocol that not only stopped her disease but reversed it.In this episode, I sit down with the incredible Dr. Terry Wahls, who shares her stunning story of going from being unable to sit up on her own to walking, biking, and jogging again. Dr. Wahls explains how she used functional medicine and a deep understanding of mitochondrial health to reclaim her life from progressive Multiple Sclerosis. She reveals the specific diet, exercise, and electrical stimulation methods that were central to her recovery."I was happy to die today to avoid being disabled tomorrow." ~ Dr. Terry WahlsMentioned in the Episode:Dr. Wahls' Clinical Trials: https://terrywahls.com/trials About Dr. Terry Wahls:Dr. Terry Wahls is a clinical professor of medicine at the University of Iowa, where she conducts clinical trials. She is also a patient with secondary progressive multiple sclerosis, which confined her to a tilt-recline wheelchair for four years. Dr. Wahls restored her health using a diet and lifestyle program she designed specifically for her brain and now pedals her bike to work. She is the author of The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles, and the cookbook, The Wahls Protocol Cooking for Life.Connect with Dr. Terry Wahls:- Website: https://terrywahls.com/ - Instagram: https://www.instagram.com/drterrywahls/ - Facebook: https://www.facebook.com/TerryWahls/ - YouTube: https://www.youtube.com/c/TerryWahlsMD Connect with Chris Burres:- Website: https://www.myvitalc.com/ - Website: http://www.livebeyondthenorms.com/ - Instagram: https://www.instagram.com/chrisburres/ - TikTok: https://www.tiktok.com/@myvitalc - LinkedIn: https://www.linkedin.com/in/chrisburres/ 

Back in Episode #401, we reported promising results from a Phase 2 clinical trial for vidofludimus calcium and its impact on progressive MS. This therapy is being developed by Immunic Therapeutics, and this week, Jason Tardio, Immunic's President and Chief Operating Officer, joins me to share some of the specifics of that clinical trial.    Jason will also shed light on why Immunic believes that vidofludimus calcium goes beyond merely slowing disability, potentially offering vital neuroprotection for MS patients, making it a potential game-changer. We're also sharing the encouraging results from a study that focused on the efficacy of neural stem cell transplantation as a remyelination therapy. We'll tell you about a study in the U.K. that measured disability progression among people with MS five years after undergoing autologous hematopoietic stem cell transplantation (aHSCT). You'll learn about an AI tool that can predict whether someone living with MS is likely to experience progression independent of relapse activity (PIRA) with a high degree of accuracy. We'll tell you where you can catch the International Progressive MS Alliance webcast featuring a panel of experts discussing the future role of digital tools in MS research. We'll explain how one of the less publicized aspects of the One Big Beautiful Bill Act will impact future MS care. And Crush MS is less than two weeks away! We're sharing all the details! We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Encouraging results from a clinical trial for progressive MS.  :22 How a less-publicized aspect of the One Big Beautiful Bill Act will impact future MS patient care 1:18 A study looked at the efficacy of neural stem cell transplantation as a remyelination therapy  4:31 A study in the U.K. analyzed disability progression among people with MS five years after receiving autologous hematopoietic stem cell therapy (aHSCT)   7:42 Can AI accurately predict who will experience progression independent of relapse activity (PIRA)?  10:45 Don't miss the International Progressive MS Alliance webcast featuring experts discussing the future role of digital tools in MS research  12:40 Are you ready to support MS research while spending the afternoon in a Napa Valley vineyard? Get all the details to attend Crush MS  13:45 Jason Tardio, President and Chief Operating Officer of Immunic Therapeutics, discusses the recent Phase 2 clinical trial for vidofludimus calcium as a therapy for progressive MS  15:03 Share this episode  30:03 Have you downloaded the free RealTalk MS app?  30:23 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/411 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist https://nationalmssociety.org/advocacy STUDY: Remyelination of Chronic Demyelinated Lesions With Directly Induced Neural Stem Cells https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awaf208/8185601 STUDY: Autologous Haemotopoietic Stem Cell Transplantation in the U.K.: A 20-Year Retrospective Analysis of Activity Haematological Outcomes from the British Society of Blood And Marrow Transplantation and Cellular Therapy https://onlinelibrary.wiley.com/doi/epdf/10.1111/bjh.20199 STUDY: Deep Learning to Predict Progression Independent of Relapse Activity at a First Demyelinating Event https://academic.oup.com/braincomms/article/7/4/fcaf243/8185588 WEBCAST: A Discussion From the International Progressive MS Alliance's Digital Tools Workshop https://msif.org/news/2025/07/08/webcast-digital-tools EVENT: Crush MS https://crushms.org Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 411 Guest: Jason Tardio Privacy Policy

Figuring out if your multiple sclerosis is changing from the relapsing remitting to the secondary progressive stage can be murky. Signs of progression are discussed like slower walking and worsening memory. The underlying reasons for progression are revealed including nervous system injury, remyelination failure, chronic inflammation and aging. Practical ways to improve progressive symptoms are shared. Successful trials for disease-modifying therapy for secondary progressive multiple sclerosis (SPMS) are highlighted. Tolebrutinib, under expedited review by the FDA, has been shown to slow down progression in SPMS patients by targeting cells in the central nervous system causing chronic inflammation. Introducing our new co-host Jamie Holloman MD from The MS Center for Innovations in Care!  Dr. Holloman completed in neurology residency at Washington University, followed by a 3-year fellowship at the Cleveland Clinic.  He interviews: Christopher Laganke MD, Founder of the Joanne P. LaGanke MS Center, Cullman, Alabama Barry Singer MD, Director of The MS Center for Innovations in Care, Missouri Baptist Medical Center, St. Louis    

Send us a message about the podcast. For questions about MS please contact our helpline 0800 032 38 39Have you been told "nothing can be done" to treat progressive MS? Then this is the episode for you. Join Nick and Helena as they debunk this myth with the expertise of neurologist Dr. Emma Tallantyre, exploring current medical and non-medical treatments, effective symptom management, and rehabilitation therapies. Plus, get the inside scoop on the MS Trust's new book, "Progression in MS," from its creators. Get informed, feel supported, and discover the resources available to help you make sense of progressive MS.Episode notesProgression in MS free book from MS Trustmstrust.org.uk/a-z/secondary-progressive-ms - secondary progressive MS info from the MS Trustmstrust.org.uk/a-z/primary-progressive-ms - primary progressive MS info from the MS Trustmstrust.org.uk/information-support/wellbeing-ms/ms-and-your-emotions  - MS and your emotions  info from the MS Trustwww.facebook.com/groups/advancedmscareandsupport - MS Trust facebook group for people with advanced MS and their carers.www.facebook.com/groups/multiplesclerosistrust - MS Trust facebook group 

Welcome to Living Well with MS - your go-to podcast for making informed choices to support your health and well-being with MS! In today's episode, we're thrilled to welcome a very special guest: comedian and MS advocate Rabiah Coon! Rabiah joins host Geoff to share her journey with MS, how she discovered Overcoming MS through a video shoot, and why she believes that laughter should be the 8th pillar of the program. Tune in as Rabiah blends humour with honesty, offering unique insights into life with MS while highlighting the power of positivity and community. You won't want to miss this conversation! Topics and Timestamps 01:29 Meet Rabiah and hear about her journey with MS. 02:31 Finding hope: how Rabiah discovered Overcoming MS through a video shoot. 05:13 Making lifestyle changes: Rabiah shares how she has approached change. 07:15 Transcendental meditation and mindfulness tips. 10:05 Retreat reflections: what it was like to attend an Overcoming MS retreat. 13:37 How Rabiah became a stand-up comedian. 17:17 Laughter as the 8th Pillar. 21:00 Rabiah's passion for volunteering and the importance of giving back. 26:44 Rabiah's top tips for the newly diagnosed.   Want to learn more about living a full and happy life with multiple sclerosis?  Sign up to our newsletter to hear our latest tips. More info and links: Watch the Hope Reborn music video Volunteer with Overcoming MS Learn more about Overcoming MS retreats Learn more about Transcendental Meditation Listen to mindfulness podcast episodes with Phil Startin S5E14 Webinar highlights: Mindfulness and Meditation with Phil Startin S5E19 Webinar highlights: Progressive MS with Phil Startin and Helen Rees Leahy S6E21 Webinar Highlights: Reducing Stress through meditation and mindfulness with Dr Phil Startin S7E04 Webinar highlights – Stress management and mental health Join MS-UK's 8-week mindfulness based stress reduction Check out Rabiah's Website: https://www.rabiahsaid.com Connect with Rabiah on social media https://linktr.ee/rabiahcomedy New to Overcoming MS? Visit our introductory page   Connect with others following Overcoming MS on the Live Well Hub  Visit the Overcoming MS website     Don't miss out:  Subscribe to this podcast and never miss an episode. Listen to our archive of Living Well with MS here. Make sure you sign up to our newsletter to hear our latest tips and news about living a full and happy life with MS. Feel free to share your comments and suggestions for future guests and episode topics by emailing podcast@overcomingms.org.   If you like Living Well with MS, please leave a 5-star review. Support us: If you enjoy this podcast and want to support the ongoing work of Overcoming MS, you can leave a donation here.

Send us a message about the podcast. For questions about MS please contact our helpline 0800 032 38 39In this bonus episode, we share some people with MS journeys of coming to terms with a progressive MS diagnosis. Adam, who lives with secondary progressive MS, is joined by his wife and carer, Sharon. Together, they reflect on how they navigate the complexities of their shared experience, from the emotional challenges to the practical ways they've found balance and connection.  Yvonne, living with primary progressive MS, opens up about how she dealt with her diagnoses, the initial shock and anger, and how she gradually discovered ways to regain a sense of control.Episode notesmstrust.org.uk/a-z/secondary-progressive-ms - secondary progressive MS info from the MS Trustmstrust.org.uk/a-z/primary-progressive-ms - primary progressive MS info from the MS Trustmstrust.org.uk/information-support/wellbeing-ms/ms-and-your-emotions  - MS and your emotions  info from the MS Trustwww.facebook.com/groups/advancedmscareandsupport - MS Trust facebook group for people with advanced MS and their carers.www.facebook.com/groups/multiplesclerosistrust - MS Trust facebook group instagram.com/meyouandmultiplesclerosis - Adam and Sharon's instagram account 

Send us a message about the podcast. For questions about MS please contact our helpline 0800 032 38 39Receiving the news that your MS is progressing can be a life-altering moment. In this podcast episode, we explore the emotional impact of this change and the journey towards acceptance and adjustment.Helena and Nick are joined by Dr Angeliki Bogosian, a health psychologist specialising in MS, who shares insights on coping strategies, the importance of psychological support, and how mindfulness can help with emotional adjustment.We also hear real-life stories from Adam and Sharon, as well as Yvonne, who open up about their experiences of living with progressive MS. From the initial shock and frustration to finding ways to regain control and maintain a fulfilling life, their stories are brimming with honesty and useful tips.Whether you're newly diagnosed, supporting a loved one, or navigating changes in your MS, this episode is here to remind you that you're not aloneListen now for expert information, real-life experiences, and practical ways to move forward with confidence.Episode notesmstrust.org.uk/a-z/secondary-progressive-ms - secondary progressive MS info from the MS Trustmstrust.org.uk/a-z/primary-progressive-ms - primary progressive MS info from the MS Trustmstrust.org.uk/information-support/wellbeing-ms/ms-and-your-emotions  - MS and your emotions  info from the MS Trustwww.facebook.com/groups/advancedmscareandsupport - MS Trust facebook group for people with advanced MS and their carers.www.facebook.com/groups/multiplesclerosistrust - MS Trust facebook group instagram.com/meyouandmultiplesclerosis - Adam and Sharon's instagram account 

Welcome to Living Well with MS, the podcast that empowers you to take control of your health and wellbeing. Today we're sharing the highlights from our webinar with the incredible Dr Phil Startin! Phil is an Overcoming MS facilitator who lives with progressive MS. He's an expert in meditation and mindfulness and teaches Mindfulness Based Stress Reduction courses for people with MS. Phil gave us some brilliant information and really useful tips on how to meditate – it's a fascinating listen whether you are a regular meditator or are just getting started with your practice. Let us know what you think! Watch this episode on YouTube here. Keep reading for the key episode takeaways.   Topics and Timestamps: 01:22 Phil's background in meditation and mindfulness 03:33 The fight or flight response 04:49 How stress dysregulates our immune system 08:47 Meditation is clinically proven to help people cope with stress 10:41 Mini meditations to try throughout the day 13:49 Guided meditation 20:06 A definition of mindfulness 23:50 The benefits of awareness, including increased resilience 28:02 Mental health tips for your daily routine   Want to learn more about living a full and happy life with multiple sclerosis?  Sign up to our newsletter to hear our latest tips. More info and links: Phil Startin has been on two other Living Well with MS episodes: S5E19 Webinar highlights: Progressive MS with Phil Startin and Helen Rees Leahy S5E14 Webinar highlights: Mindfulness and Meditation with Phil Startin Jon Kabat-Zinn's Mindfulness Based Stress Reduction Dr Walter Cannon's fight or flight response Meditation expert Ian Gawler Listen to meditation expert Craig Hassed S5E13 Meditation tips with Professor Craig Hassed S1E7 Building a daily meditation practice with Dr Craig Hassed Shannon Harvey's film My Year of Living Mindfully or listen to her podcast episode Hardwiring Happiness by Rick Hanson New to Overcoming MS? Visit our introductory page Connect with others following Overcoming MS on the Live Well Hub Visit the Overcoming MS website Follow us on social media: Facebook Instagram YouTube Pinterest Don't miss out:  Subscribe to this podcast and never miss an episode. Listen to our archive of Living Well with MS episodes here. If you like Living Well with MS, please leave a 5-star review. Feel free to share your comments and suggestions for future guests and episode topics by emailing podcast@overcomingms.org. Make sure you sign up to our newsletter to hear our latest tips and news about living a full and happy life with MS. Support us:  If you enjoy this podcast and want to support the ongoing work of Overcoming MS, we would really appreciate it if you could leave a donation here. Every donation, however small, helps us to share the podcast with more people on how to live well with MS.

As Harvard Fellow Dr. Nara Michaelson treated women who had been recently diagnosed with MS, she recognized they shared characteristics that she had observed in victims of violent domestic abuse. Dr. Michaelson's observation led her to write The Unraveling, an essay that highlights the fear that can accompany the uncertainty of living with MS.  Dr. Michaelson joins me to discuss the experiences that led to her award-winning essay and to share resources that can help maintain your emotional health and well-being in a good place when you're living with MS. We're also sharing the details about BEAT-MS, a clinical trial that will compare autologous hematopoietic stem cell transplantation (AHSCT) with high-efficacy disease-modifying therapies when it comes to reducing or eliminating MS relapse activity. And we'll let you know how to find out if you could be a potential participant in this important clinical trial.  We'll tell you about the FDA approval granted to Abata Therapeutics to conduct a Phase 1 clinical trial of ABA-101, their experimental therapy for progressive MS. We're sharing news about the Federal Trade Commission's newly released report on Pharmacy Benefit Managers. (And we'll tell you why this matters to every person in the United States who takes a prescription medication) And we'll tell you about Take Charge, a new virtual program from Can Do MS that you can participate in at no cost! We have a lot to talk about! Are you ready for RealTalk MS??! This Week: The Unraveling  :22 BEAT-MS clinical trial compares AHSCT with high-efficacy DMTs  1:58 FDA clears ABA-101 for Phase 1 clinical trial  5:17 FTC is turning its focus to Pharmacy Benefit Managers  6:55 Can Do MS offers new Take Charge virtual program  11:47 Dr. Nara Michaelson discusses her award-winning essay, The Unraveling  13:23 Share this episode  29:15 Next week: Dr. Riley Bove discusses how digital technology has become a game-changer in diagnosing, treating, and managing MS  29:35 Have you downloaded the free RealTalk MS app?  29:55 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/359 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com The Unraveling https://neurology.org/doi/10.1212/WNL.0000000000209492 BEAT-MS Clinical Trial https://beat-ms.org RealTalk MS Episode 205: A Potentially Transformational Therapy for Progressive MS with Samantha Singer and Dr. Richard Ransohoff https://realtalkms.com/205 FTC Report -- Pharmacy Benefit Managers: The Powerful Middlemen Inflating Drug Costs and Squeezing Main Street Pharmacies https://ftc.gov/system/files/ftc_gov/pdf/pharmacy-benefit-managers-staff-report.pdf REGISTER for Take Charge https://cando-ms.org/event/take-charge-young-and-newly-diagnosed Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 359 Guests: Dr. Nara Michaelson Privacy Policy  

When it comes to living your best life when you're living with MS, the first step is to make smart lifestyle choices. Maintaining a healthy lifestyle doesn't require pills, injections, or infusions. And making smart lifestyle choices can make a real, measurable difference in your quality of life. Joining me to talk about the benefits of maintaining a healthy lifestyle and share some tips and strategies for living your best life when you're living with MS is Dr. Lisa Doggett, a family and lifestyle medicine physician at the MS and Neuroimmunology Center at Dell Medical School at the University of Texas at Austin. Dr. Doggett was diagnosed with MS in 2009, and she's the author of the memoir, ‘Up the Down Escalator: Medicine, Motherhood, and Multiple Sclerosis'. We'll also tell you about a research team that's looking to improve the way that stem cells are transplanted -- and why that's a good thing for people with MS. We'll share the details behind the European Union's approval of a new Ocrevus formulation that makes the DMT much more patient-friendly. You'll hear about the blood test for measuring a biomarker that can predict future MS disease worsening that has just gained approval in the European Union. And we'll tell you where to find the video replay of Mobility Challenges in Progressive MS, the most recent webcast hosted by the International Progressive MS Alliance. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Lifestyle changes that will improve your quality of life  :22 Researchers receive a grant to develop a better way to transplant stem cells  1:30 Subcutaneous Ocrevus has been approved in the European Union  3:50 Blood test to measure a biomarker that can predict future MS disease worsening receives approval in the European Union 5:35 Catch the video replay of the latest Progressive MS Alliance webcast  7:13 Dr. Lisa Doggett offers strategies for making lifestyle choices that will make a difference in your quality of life  8:20 Share this episode  26:50 Next Week: Dr. Jaime Imitola introduces us to VISIBL-MS  27:10 Have you downloaded the free RealTalk MS app?  27:39 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/357 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com VIDEO REPLAY of the International Progressive MS Alliance Global Webcast: Mobility Challenges in Progressive MS https://youtube.com/watch?v=YGA-2k9JCLg&t=14s Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 357 Guests: Dr. Lisa Doggett Privacy Policy  

Research is the engine that drives the future. And participating in MS research is not only vital to improving scientists' understanding of multiple sclerosis, it's also empowering. And the really good news is that you can participate in MS research from the comfort of your own home. My guest this week is the Managing Director of the North American Research Committee on Multiple Sclerosis, Dr. Robert Fox. And we're taking a deep dive into the NARCOMS patient registry. We'll also tell you about the latest version of AlphaFold, a highly advanced artificial intelligence model designed to help scientists design new drugs and target disease more effectively. Evidence shows that the Epstein-Barr Virus (EBV) triggers MS. We're reviewing the results of a study that may help scientists better understand the relationship between EBV and MS.  The International Progressive MS Alliance upcoming webcast, Mobility Challenges in Progressive MS, takes place this Thursday, June 20th. Find out where you can register and why you won't want to miss this! And we're just 6 weeks away from Crush MS, a fundraising event in Napa Valley, California that raises money to support MS research. I'll be there, and I hope you can join me! We're sharing all the details. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: The NARCOMS Patient Registry  :22 The most advanced AI on earth is focused on discovering new medications  1:40 Researchers learn that Epstein-Barr Virus re-activates and drives inflammation during an MS relapse  4:00 The Progressive MS Alliance hosts a live global webcast this Thursday, June 20th!  7:17 Crush MS is just 6 weeks away  8:39 Dr. Robert Fox takes us on a deep dive into the NARCOMS patient registry  10:08 Share this episode  26:12 Next Week: A special conversation with National MS Society President and CEO, Cyndi Zagieboylo  26:33 Have you downloaded the free RealTalk MS app?  27:17 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/355 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com The NARCOMS Patient Registry https://www.narcoms.org STUDY: Multiple Sclerosis Patient-Derived Spontaneous B Cells Have Distinct EBV and Host Gene Expression Profiles In Active Disease https://nature.com/articles/s41564-024-01699-6 REGISTER for the International Progressive MS Alliance Global Webcast: Mobility Challenges in Progressive MS https://msif.org/webcast-mobility Get Tickets for Crush MS https://www.crushms.org Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 355 Guests: Dr. Robert Fox Privacy Policy  

March 28th is Progressive MS Day, a day that offers an opportunity for people affected by MS, patient advocates, healthcare providers, governments, and industry to share stories online and show their support for people living with progressive forms of MS.  My wife, Jeanne, lived with progressive MS for 23 years, so this day holds a special significance for me. Joining me to talk about what Progressive MS Day is all about is my friend, Kevin Reid. Kevin was diagnosed with MS in 2002 and, for the past 10 years, he's been on a mission to crush MS. As MS Awareness Month draws to a close, we're sharing a series of short videos featuring conversations I had with MS experts at the ECTRIMS congress. What makes this video series unique is that iConquer MS invited people living with MS to watch these videos. Then, I interviewed them to get their perspective on the topics the experts were discussing. It's the first time you'll not only hear from the experts, but you'll also get the thoughts and reactions of people who are living with MS. We'll tell you about the neurostimulator that was just designated as a Breakthrough Device for promoting myelin repair. We'll share the details of a newly announced Phase 2 clinical trial for a T-cell therapy for MS. You'll hear about the study that identified a biomarker that reliably predicted the likelihood of future disease activity in people with MS. And we'll tell you where you can catch the video replay of the 2024 ACTRIMS Forum Patient-Centered Webinars. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: March 28th is Progressive MS Day  :22 Have you seen the series of short videos featuring my conversations with MS experts at ECTRIMS along with the thoughts and reactions from people living with MS?  1:00 Catch the video replay of the 2024 ACTRIMS Forum Patient-Centered Webinars  1:57 FDA designates neurostimulator as a breakthrough device for promoting myelin repair in people living with relapsing-remitting MS  2:46 Biotech company PolTREG announces Phase 2 clinical trials to test their Tregs treatment for MS  5:28 Study shows neurofilament light chain levels can reliably predict future disease activity  7:10 Kevin Reid discusses the importance of Progressive MS Day and gives us a preview of CRUSH MS  10:35 Share this episode  28:09 Have you downloaded the free RealTalk MS app?  28:29 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/343 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com VIDEO: Dr. Jiwon Oh shares encouraging results from an extension study of Tolebrutinib, an investigational disease-modifying therapy. Then, two people living with MS share their thoughts about clinical trials and a precision medicine approach to treating MS https://youtu.be/eWoZLF4bZmo VIDEO: Dr. Anthony Feinstein discusses the outcome of the CogEx study, Then, two people living with MS share their thoughts about the impact of this study https://www.youtube.com/watch?v=UtGtCnNkYOY VIDEO: Dr. Annette Langer-Gould discusses the impact of other health conditions on people living with MS. Then, two people living with MS share their thoughts and experiences of  managing their MS along with additional health conditions https://www.youtube.com/watch?v=J83jlqMbsZo VIDEO: Dr. Daniel Ontaneda discusses how artificial intelligence will impact MS treatment. Then, two people living with MS share their thoughts on the potential impact of AI on MS treatment and the future patient experience https://www.youtube.com/watch?v=_fRLW69Xc1A VIDEO: Dr. Robert Motl discusses the benefits of exercise for people living with MS. Then, two people living with MS share their thoughts on how exercise has impacted their MS journey https://www.youtube.com/watch?v=oZDdp8JumFg VIDEO: ACTRIMS Forum 2024 Webcast Replays https://actrims.memberclicks.net/forum-patient-centered-webinars STUDY: Prognostic Value of Serum Neurofilament Light Chain for Disease Activity and Worsening in Patients with Relapsing Remitting Multiple Sclerosis: Results from the Phase 3 ASCLEPIOS I and II Trials https://pubmed.ncbi.nlm.nih.gov/35432382 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 343 Guest: Kevin Reid Privacy Policy

Welcome to Living Well with MS, where we are pleased to welcome Dr Stefano Pluchino as our guest! Dr Pluchino is a Professor of Regenerative Neuroimmunology at Cambridge University and has been researching stem cell therapy for progressive MS. In this episode, Dr Pluchino speaks to Geoff about what advanced cell therapy is, the success of his phase one trial and what the future of DMTs looks like indicating what people with MS may experience. Watch this episode on YouTube here. Keep reading for the key episode takeaways. Topics and Timestamps: 01:31 Dr Pluchino's background and research into stem cell therapy for progressive MS. 02:52 The difference between types of MS. 05:09 Navigating DMT options for progressive MS. 08:40 Dr Pluchino's advanced cell therapy research trial: The success of phase one and plans for phase two. 21:05 How advanced cell therapy compares to HSCT or bone marrow transplants. 26:02 What it means for the future of DMTs. 33:39 How you can be part of groundbreaking MS research and trials. Selected Key Takeaways: There are nuances in types of MS beyond ‘relapsing' or ‘progressive'. 04:23 "It is becoming more complex between active and non-active types of primary and secondary progressive MS where activity is attributed to other episodes. Clinical episodes of disease or radiologically evident episodes of disease, which can be identified by the use of contrast agents at the time of the MRI. So, they are very complex very heterogenous types of disease, with or without activity, which inevitably undergo accumulation of neurological deficits.” The next generation of DMTs will target progression rather than relapses. 06:39 “What's becoming very interesting is that [over the last] few years, there is a general worldwide consensus that progressive MS is becoming and has become a clinical unmet need. The old MS world is concentrating on financing, funding and efforts towards stopping MS through the development of a new generation of DMDs which will eventually target progression rather than relapses.” The future of advanced cell therapy research will look at remyelination, reduction of inflammation and neuroprotection. 19:10 "There is space for assessing whether a proportion of the injected cells [can] differentiate in vivo into new myelin-forming cells. There is a space to assess whether some of the cells [can] increase the survival of neurons in the brain. There is space to assess whether the transplanted cells [can] reduce the type of inflammation which characterises progressive MS, which is what we call a smouldering inflammation. These highly diffuse homogeneous, low-level activations of microglia (immune cells of the central nervous system) and astrocytes (star-shaped cells that hold nerve cells in place) might be reduced by means of advanced cell therapy and the reason why I am specifically alluding to these three major biological mechanisms of disease, remyelination, reduction of inflammation and neuroprotection is because we have managed to identify each of these mechanisms in clinically relevant animal disease models in the last 25 years. So, there is [an] expectation that a clinical trial designed in a way that will allow us to establish the efficacy of the treatment will reveal what we have established already in one of these models.” Want to learn more about living a full and happy life with multiple sclerosis? Sign up to our newsletter to hear our latest tips. More info and links: Video on Early-stage stem cell therapy trial shows promise for treating progressive MS Dr Pluchino's website Dr Pluchino's bio If you have progressive MS you may be eligible for the Octopus trial Learn about HSCT from Professor Richard Burt in Season 5 Episode 25 Read about the Shinya Yamanaka  and John Gurdon'a Nobel Winning iPSC technology Find out more about the latest research in progressive MS from the International Progressive MS Alliance New to Overcoming MS? Visit our introductory page  Connect with others following Overcoming MS on the Live Well Hub Visit the Overcoming MS website Follow us on social media: Facebook Instagram YouTube Pinterest Don't miss out:  Subscribe to this podcast and never miss an episode. Listen to our archive of Living Well with MS episodes here. If you like Living Well with MS, please leave a 5-star review. Feel free to share your comments and suggestions for future guests and episode topics by emailing podcast@overcomingms.org. Make sure you sign up to our newsletter to hear our latest tips and news about living a full and happy life with MS. Support us:  If you enjoy this podcast and want to support the ongoing work of Overcoming MS, we would really appreciate it if you could leave a donation here. Every donation, however small, helps us to share the podcast with more people on how to live well with MS.

We often discuss the results of MS research studies on this podcast. In order to get to those results, people living with MS have to step up and volunteer to participate. This week, you'll meet Chiquita Shepard-Knight and Earl Sneed, two participants in the TEAAMS study. Chiquita and Earl will discuss how they discovered the TEAAMS study, what motivated them to get involved, what their experience as study participants was like, and what the results of the study were for them. We'll also take you to Capitol Hill as we share conversations that we had during Hill Day at the National MS Society's Public Policy Conference.  It's MS Awareness Month, and we're sharing new videos that feature interviews with leading MS experts along with the thoughts and reactions of people living with MS. And we'll tell you where you can catch the video replay of the International Progressive MS Alliance's webcast on emerging treatments for progressive MS. We have a lot to talk about! Are you ready for RealTalk MS??! Tomorrow! The ACTRIMS Post-Forum Patient-Centered Webinar  :22 This Week: The patient perspective on participating in an MS research study  1:38 Live! From the Natinal MS Society's Public Policy Conference  2:28 People with MS weign in on the impact of several ECTRIMS presentations  10:17 Catch the video replay of the International Progressive MS Alliance webcast  11:35 Chiquita Shepard-Knight and Earl Sneed discuss their experience participating in the TEAAMS study   12:11 Share this episode  27:18 Have you downloaded the free RealTalk MS app?  27:38 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/342 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com REGISTER: ACTRIMS Post-Forum Patient-Centered Webinar https://fs2.formsite.com/1FItkk/tgx8tu3xg0/index VIDEO: Dr. Jiwon Oh shares encouraging results from an extension study of Tolebrutinib, an investigational disease-modifying therapy. Then, two people living with MS share their thoughts about clinical trials and a precision medicine approach to treating MS https://youtu.be/eWoZLF4bZmo VIDEO: Dr. Anthony Feinstein discusses the outcome of the CogEx study, Then, two people living with MS share their thoughts about the impact of this study https://www.youtube.com/watch?v=UtGtCnNkYOY VIDEO: Dr. Annette Langer-Gould discusses the impact of other health conditions on people living with MS. Then, two people living with MS share their thoughts and experiences of  managing their MS along with additional health conditions https://www.youtube.com/watch?v=J83jlqMbsZo VIDEO: Dr. Daniel Ontaneda discusses how artificial intelligence will impact MS treatment. Then, two people living with MS share their thoughts on the potential impact of AI on MS treatment and the future patient experience https://www.youtube.com/watch?v=_fRLW69Xc1A VIDEO: Dr. Robert Motl discusses the benefits of exercise for people living with MS. Then, two people living with MS share their thoughts on how exercise has impacted their MS journey https://www.youtube.com/watch?v=oZDdp8JumFg VIDEO: International Progressive MS Alliance Webcast Replay: Emerging Treatments for Progressive MS https://www.youtube.com/watch?v=W4hxtl38MBQ The TEAAMS Study https://projectteaams.ahs.uic.edu Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 342 Guests: Chiquita Shepard-Knight and Earl Sneed Privacy Policy

Progressive MS Research Update - Episode 167 - Transcript - This episode of the Can Do MS Podcast welcomes guest Dr. Bruce Bebo who is the Executive Vice President of Research at the National MS Society. Bruce and host, Stephanie talk about what's on the forefront of Progressive MS Research. Learn about the projects, trials, and collaborations that are currently happening around the globe. The sheer amount of research that's being done is cause for optimism.

According to the CDC, 36 million falls are reported each year, resulting in 3 million adults being transported to the Emergency Room and 32,000 adults dying from their falls. Studies have shown that, in any six-month period, more than 50% of the people living with MS fall at least once, and 30% fall multiple times. As falls at home are common, occupational therapist Tracy Carrasco joins me to share tips and strategies for making your home safe and accessible. We're also sharing a research roundup featuring results from a few different clinical trials that are focused on the impact of diet on MS. And that includes the Swank diet, the Wahls diet, the Mediterranean diet, and a simple low-fat diet. We'll tell you about a novel study that explored the economic impact of an Epstein-Barr Virus vaccine on the cost of MS care in Australia. If you're living with MS, we have your invitation to participate in the Patient Reported Outcomes for Multiple Sclerosis (PROMS) initiative survey. And we'll tell you how you can catch the video replay of the International Progressive MS Alliance global webcast on research and treatment for cognitive challenges in progressive MS. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Some of the things I'm thankful for  :22 Research Roundup: The impact of diet on MS  2:40 Survey results show how an EBV vaccine could impact the cost of MS care in Australia  9:03 If you're living with MS, here's your invitation to participate in the PROMS initiative online survey  12:22 How to catch the video replay of the International Progressive MS Alliance global webcast about research and treatment for cognitive challenges in progressive MS 13:38 Tracy Carrasco shares tips for making your home safe and accessible 15:25 Share this episode  27:26 Have you downloaded the free RealTalk MS app?  27:46 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/325 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com STUDY: A Low-Fat Diet Improves Fatigue in Multiple Sclerosis: Results from a Randomized Controlled Trial https://journals.sagepub.com/doi/10.1177/13524585231208330 STUDY: Diet-Induced Changes in Functional Disability are Mediated by Fatigue in Relapsing-Remitting Multiple Sclerosis: A Secondary Analysis of the WAVES Randomized Parallel-Arm Trial https://journals.sagepub.com/doi/full/10.1177/20552173231209147 STUDY: Exploring the Cost-Effectiveness of EBV Vaccination to Prevent Multiple Sclerosisin an Australian Setting https://jnnp.bmj.com/content/early/2023/11/02/jnnp-2023-332161 PARTICIPATE: The PROMS Initiative Survey https://proms-initiative.org/survey-proms VIDEO: Cognitive Challenges in Progressive MS https://youtube.com/watch?v=bN26GrRZMts Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 325 Guest: Tracy Carrasco Privacy Policy

More than 70,000 U.S. veterans are living with MS. That's why the only federal funding specifically earmarked for MS research comes from the U.S. Department of Defense. It's why the U.S. Department of Veterans Affairs has established the Multiple Sclerosis Centers of Excellence. And it's why, in 2019, the National MS Society established a strategic partnership with the U.S. Department of Veterans Affairs. This week, we're saluting the men and women of our armed services, and we're highlighting some of the resources available to U.S. veterans who are living with MS. Izzy Abbass, the Co-Chair of the Paralyzed Veterans of America MS Committee, joins me to discuss all the ways the PVA assists U.S. veterans in obtaining their VA benefits. We're also sharing the results of a study that compared the efficacy of being treated with autologous hematopoietic stem cell transplantation (aHSCT) and being treated with a high-efficacy disease-modifying therapy.  We'll tell you about the results of a study that may begin to explain why African Americans who are living with MS often experience a more severe disease course. We'll give you the details about where and how to register for this Thursday's International Progressive MS Alliance's global webcast that's focused on treatments and new research for cognitive challenges in progressive MS. And actress Jamie-Lynn Sigler is also joining me this week to talk about her MS journey and to share some news about a new project that she has developed for people living with MS. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Resources for U.S. Veterans living with MS  :22 My guest, Izzy Abbass, explains how the PVA assists U.S. Veterans with MS in receiving their VA benefits  2:41 A study compared the efficacy of autologous hematopoietic stem cell transplantation (aHSCT) with a high-efficacy disease-modifying therapy  11:21 Results of a study may begin to explain why African Americans who are living with MS often experience a higher level of disease activity and faster disability progression  14:36 This Thursday, the International Progressive MS Alliance is hosting a global webcast exploring treatments and research focused on cognitive challenges in progressive MS  17:31 Jamie-Lynn Sigler discusses her new guide for people living with MS  19:13 Share this episode  30:25 Have you downloaded the free RealTalk MS app?  30:45 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/323 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com National MS Society: Resources for U.S. Veterans with Multiple Sclerosis https://nationalmssociety.org/Resources-Support/Find-Support/Veterans-with-Multiple-Sclerosis U.S. Department of Veteran Affairs: Multiple Sclerosis Centers of Excellence https://www.va.gov/ms Paralyzed Veterans of America: Multiple Sclerosis Resources https://pva.org/research-resources/multiple-sclerosis STUDY: Autologous Hematopoietic Stem Cell Transplantation is Superior to Alemtuzumab in Patients with Highly Active Relapsing Multiple Sclerosis and Severe Disability https://sciencedirect.com/science/article/pii/S2211034823005977 STUDY: African American Patients with Multiple Sclerosis (MS) Have Higher Proportions of CD19+ and CD20+ B-Cell Lineage Cells in Their Cerebrospinal Fluid than White MS Patients https://sciencedirect.com/science/article/abs/pii/S2211034823005485 REGISTER for Thursday's Global Webcast on Cognitive Challenges in Progressive MS https://msif.org/cognitive-webcast Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 323 Guests: Izzy Abbass and Jamie-Lynn Sigler Privacy Policy

Artist, Rebel, and Progressive MS Warrior - Episode 146 - Transcript - Meet street artist, rebel, and progressive MS warrior Lydia Emily. She shares her life with us including the story of her MS diagnosis, adaptations she made, and some stories and experiences from creating art. Lydia Emily's approach to her MS is real and refreshing. She sees strength in seeking out adaptations, asking for help, and making the adjustments needed to live a happy and easier life with MS. Keep your eye out for Lydia Emily's upcoming book The Art of Hope. You can learn more about Lydia Emily and her art via her website - https://lydiaemily.com/ and her Instagram @lydiaemily.  

Today, I have a very special guest with me. Her name is Susan! I have had the opportunity to work with Susan in my 1:1 Mentor Membership program, and now she has continued on with The MSing Link program. Susan has seen so much improvement in her goals of standing for longer periods of time, improving her walking, and more! She shares her journey to diagnosis, about having spinal cord lesions, and her overall experience with the programs. Tune in to be inspired! Watch a Behind the Scenes video on The MSing Link HERE OR check out the website, linked below. Apply for the 1:1 Mentor Membership Program HERE Additional Resources: https://www.doctorgretchenhawley.com/insider Reach out to Me: hello@doctorgretchenhawley.com Website: www.MSingLink.com Social: ★ Facebook: https://www.facebook.com/groups/mswellness ★ Instagram: https://www.instagram.com/doctor.gretchen ★ YouTube: https://www.youtube.com/c/doctorgretchenhawley?sub_confirmation=1 → Game Changers Course: https://www.doctorgretchenhawley.com/GameChangersCourse → Total Core Program: https://www.doctorgretchenhawley.com/TotalCoreProgram → The MSing Link: https://www.doctorgretchenhawley.com/TheMSingLink

In this episode, we are sharing the highlights from our webinar ‘Living Well with Progressive MS' with Dr Phil Startin and Professor Helen Reese Leahy. Both Phil and Helen have progressive MS and follow the Overcoming MS Program. They discuss what progressive MS is and how the Overcoming MS Program can benefit people with progressive MS. This webinar was recorded in July 2021 as part of our Finding Hope with Overcoming MS webinar series. You can watch the whole webinar here or the podcast highlights on YouTube here. Keep reading for the key episode takeaways and bio information. Make sure you sign up to our newsletter to hear our latest tips and news about living a full and happy life with MS. And if you're new to Overcoming MS, visit our introductory page to find out more about how we support people with MS. Selected Key Takeaways Overcoming MS is for every type of MS Helen Rees Leahy: “Overcoming MS is really determined to be an inclusive space in which everybody's experience of MS is acknowledged and honoured. So, though we [people with progressive MS] may be small in number, our voice is growing, and we're very much being heard within the Overcoming MS conversation.” Exercise is still important with progressive MS but be gentle and kind with yourself Phil Startin: “Be kind to yourself, try not to judge [and] compare what you can do now to what you used to be able to do. I've certainly spoken to people who refuse to exercise saying exercising reminds them of what they now can't do and that's really upsetting. We still need goals but hold them more lightly [and] more gently.” Think of the Overcoming MS Program as a toolkit rather than a set of rules Helen Reese Leahy: “I started following the Overcoming MS Program in the 2000s. It's become a framework for my daily life. I've never been eligible for any disease-modifying therapy, so in a sense, Overcoming MS is my health care programme. I feel very empowered by following the Program. I am taking responsibility and managing my own health to the best of my ability. I always regard Overcoming MS not as a book of rules, but as a kind of toolkit and to be honest, I really enjoy following the Program.” More info and helpful links: Watch the original webinar here Try yoga with Overcoming MS facilitator Veronique Gauthier-Simmons here Read more about Progressive MS Join the Progressive MS Circle New to Overcoming MS? Visit our introductory page Visit the Overcoming MS website Follow us on social media: Facebook Instagram Twitter YouTube Pinterest Don't miss out: Subscribe to this podcast and never miss an episode. Listen to our archive of Living Well with MS episode here. If you like Living Well with MS, please leave a 5-star review. Feel free to share your comments and suggestions for future guests and episode topics by emailing podcast@overcomingms.org. Make sure you sign up to our newsletter to hear our latest tips and news about living a full and happy life with MS. If you enjoy this podcast and want to support the ongoing work of Overcoming MS, you can leave a donation here. Dr. Phil Startin's bio: Career and Overcoming MS: After a DPhil in Quantum Physics, Phil left his academic roots for a more peripatetic career in management consulting, initially with Price Waterhouse. After years of travelling around the world for both work and pleasure, including a two-year assignment in Geneva, he was diagnosed with Primary Progressive MS (PPMS) in 2007.   Phil discovered Overcoming MS in 2011, and coupled with his earlier discovery of mindfulness meditation, it awakened a whole new area in his life. With training and supervision from Bangor University, he now teaches an eight-week mindfulness-based stress reduction (MBSR) course to people with MS and to the general community on a pro-bono basis. He is also a trustee for MS-UK.   Personal life: Phil lives in Arrochar, Scotland with his American wife, Cristina, whom he met over a weekend at the Jazz Fest in New Orleans. Phil's completely convinced that the Overcoming MS Program and mindfulness have positively affected the trajectory of his condition Professor Helen Rees Leahy's bio: MS and Overcoming MS: Helen was diagnosed with Primary Progressive MS in 1997 when she was 37 years old. Being ineligible for any Disease Modifying Treatment (DMT) within the UK National Health Service, she began to explore holistic approaches to managing her condition. She discovered Overcoming MS in 2008 and has followed the Program ever since. She was previously a Trustee for Overcoming MS. Personal life and career: Helen lives in Conwy, a small, medieval town in North Wales. In 2017, she took medical retirement from the University of Manchester where she was a Professor in the Department of Art History and Cultural Practice. As an Emerita Professor, Helen continues to research and teach doctoral students. She also spends time hand-weaving and learning Welsh, the language of her ancestors.

The Wahls Protocol - How I Beat Progressive MS Using Paleo Principles and Functional Medicine #SANE with Dr. Terry Wahls & Jonathan Bailor

Dr. Matilde Inglese discusses her article, "Hematopoietic Stem Cell Transplantation in People With Active Secondary Progressive Multiple Sclerosis". Show References: https://n.neurology.org/content/early/2022/12/21/WNL.0000000000206750

Dr. Shuvro Roy talks with Dr. Matilde Inglese about comparing stem-cell transplants to DMTs in patients with Secondary Progressive MS. Read the related article in Neurology®.

Darrell Wordelmann has been the face of Rooney's Oceanfront Restaurant for the last 27 years, and he loves the mental and physical challenge that the restaurant business brings.  He grew up in a house where his mother had Progressive MS. Because of this, Darrell has been an advocate for Multiple Sclerosis for over 20 years, before receiving his own diagnosis in 2020.In the first part of a two-part interview, Darrell talks about growing up in a house where he and his brother had to care for his mother, his life running a busy restaurant, and his own diagnosis with Multiple Sclerosis.Make sure you come back tomorrow to hear about Darrell's own MS diagnosis and the amazing work he does with Single Parents with MS, a charity foundation that supports families whose primary caregiver has been diagnosed with MS.Single Parents with MS, a 501(c)(3) organization, helps single parents with MS who are experiencing financial hardships. Support may range from Christmas gifts, purchasing ADA equipment, widening a doorway within a home, or helping keep the lights on during a difficult time. Anything to alleviate some of the stress that comes with MS and being a single parent.DISCLAIMERThe information contained in this podcast is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions you may have regarding a medical condition or treatment.Connect with Darrell on LinkedInVisit Rooney's Oceanfront Restaurant If you're interested in having Kathy speak at your event, learn more hereFind out more about the DMAT Fitness Training programYou can find Kathy Chester at:msdisrupted@gmail.comdisruptfitnessgym@gmail.com moveitorloseit109@gmail.com Connect with @msdisrupted on Instagram, Facebook, TikTok Here are some additional products that help Kathy deal with beating the Heat and Migraines.  Take advantage of the coupon code.Koldtec - Cool Head WrapKOLD10To save $10 off every item in-store.2 items = $20 savings3 items = $30 savingshttps://www.koldtec.com/ Cold bean bag Releafpack. 15% discount use code Disrupt15https://www.releafpack.com 

Today on Biology of Trauma, we conclude our series with Dr. Arielle Schwartz on identifying trauma and addressing the freeze response. In this episode, we hear a story of hope from Laura Bautista, a 21-day journey graduate who recovered from MS by healing her trauma.    Laura was diagnosed with degenerative MS at age 21. Western medicine determined that she had a bleak future of pain, loss of function, and even death. Like all autoimmune diseases, many seemingly random symptoms were dismissed and normalized throughout her life. It wasn't until she discovered functional medicine that Laura learned to listen to her body. For seven years, Laura slowly detoxed and began tracking her nervous system leading to a full recovery from what was diagnosed as a progressive disease.   There was never an exterior event to pin Laura's traumatic response on. However, tracking built awareness that allowed her to remove barriers to her healing. The body is naturally designed to heal itself, but stress, unhealthy foods, and lifestyles burden your body. This capacity exists within every person, and somatic tools are resources along your journey to your natural state of wellness. Simply, learning to slow down saved Laura's life. Key Takeaways: [2:20] Laura's story from progressive MS to 10 years symptom-free [4:40] Auto-immune diseases progress over the years until it becomes extreme enough to diagnose [9:00] Shifting focus from the disease to restoring function to the body  [14:58] The body heals itself when it feels calm, not when you demand it to be calm [15:55] Removing barriers to healing because the body is designed to constantly heal [18:55] Presence heals trauma, not cathartic therapies that retraumatize the mind and body [20:38] How to access a safe place to stop the spiraling  [23:20] Tracking is a basic tool that allows you to build awareness and gain perspective [24:28] How the pace of life influences your health and differentiating stress from trauma [27:42] Integrating stillness and observation into life inhibits stress from progressing into trauma [33:00] Finding hope when life feels out of control  [35:10] Detoxing from what you are not so that you can come home to yourself   Find More From Dr. Arielle Schwartz: Center for Resilience Informed Therapy    How do you know if you have trauma? And if you do have trauma, what is the next step? The good news is, there is a step-by-step process for identifying and healing trauma. Download my step-by-step guide (with a quiz inside!) to see if you have trauma and to identify how to get started. Download your free roadmap here: Steps To Identify & Heal Trauma https://traumahealingaccelerated.mykajabi.com/steps-to-identify-and-heal-trauma-a-roadmap-for-healing     Disclaimer: By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Trauma Healing Accelerated, any guests or contributors to The Biology of Trauma podcast, or any employees, associates, or affiliates of Trauma Healing Accelerated be responsible for damages arising from the use of the podcast.

Every episode of RealTalk MS features updates and reports about emerging science. And, as you listen, some of you may wonder, 'When will these scientific achievements benefit me? When will these breakthroughs and advancements make their way from the laboratory workbench to the clinic?'   That's exactly what the panel of MS experts who comprise the International Advisory Committee on Clinical Trials in MS are proposing in a new framework that leverages what scientists are continuing to learn and re-defines how we talk about MS, research MS, diagnose MS, and treat MS.  The new framework being recommended by the committee is broadly outlined in a paper that was published about 8 weeks ago. Joining me to discuss what this proposed framework is all about is the paper's lead author, Professor Tanja Kuhlmann. We're also talking about the new high-efficacy disease-modifying therapy that received its FDA approval last week. We're sharing the details behind the FDA's approval of a Phase 3 clinical trial for Masitinib, an investigational therapy for treating progressive MS. We'll tell you about Abata Therapeutics' first T-cell treatment candidate for treating progressive MS. And you'll hear about the results of a study that compared the outcome of treating people living with secondary progressive MS with autologous hematopoietic stem cell transplantation (aHSCT) versus treatment by disease-modifying therapies. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Experts recommend a new framework for researching, diagnosing, and treating MS  :22 FDA approves Ublituximab (Briumvi), an anti-cd20 disease-modifying therapy  1:12 FDA approves Phase 3 clinical trial for Masitinib as a treatment for progressive MS  4:35 Abata Therapeutics announces its first T-cell therapy candidate to treat progressive MS  7:20 Study shows aHSCT more effective than DMTs in treating secondary progressive MS  10:14 Professor Tanja Kuhlmann discusses a new framework for researching, diagnosing, and treating MS  13:51 Share this episode  26:37 Have you downloaded the free RealTalk MS app?  26:57 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/279 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com STUDY: Ublituximab versus Teriflunomide in Relapsing Multiple Sclerosis https://nejm.org/doi/full/10.1056/NEJMoa2201904 AB Science https://ab-science.com RealTalk MS Episode 205: A Potentially Transformational Therapy for Progressive MS with Samantha Singer and Dr. Richard Ransohoff https://realtalkms.com/205 STUDY: Hematopoietic Stem Cell Transplantation in People with Active Secondary Progressive MS https://n.neurology.org/content/early/2022/12/21/WNL.0000000000206750 Take the iConquer MS Caregiver Survey https://realtalkms.com/caregiver Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 279 Guest: Professor Tanja Kuhlmann Tags: MS, MultipleSclerosis, MSResearch, MSSociety, RealTalkMS Privacy Policy

Multiple Sclerosis News Today's multimedia associate, Price Wooldridge, reads a news report on ATA188, a treatment targeting the Epstein-Barr virus which could be integral in treating progressive MS. He also reads a news article reporting on how ublituximab works better than Aubagio at easing disability in patients with relapsing MS. =================================== Are you interested in learning more about multiple sclerosis? If so, please visit: https://multiplesclerosisnewstoday.com/ ===================================== To join in on conversations regarding multiple sclerosis, please visit: https://multiplesclerosisnewstoday.com/forums/

Multiple Sclerosis News Today's multimedia associate, Price Wooldridge, reads a news article on how genetic variants in genes mostly active in the central nervous system are linked to MS severity. He also reads a report on how the investigational immunotherapy ATA188 continues to ease disability and prevent brain tissue shrinkage in people with progressive forms of multiple sclerosis. =================================== Are you interested in learning more about multiple sclerosis? If so, please visit: https://multiplesclerosisnewstoday.com/ ===================================== To join in on conversations regarding multiple sclerosis, please visit: https://multiplesclerosisnewstoday.com/forums/

Multiple Sclerosis News Today's multimedia associate, Price Wooldridge, reads a news article on how off-label high-efficacy DMTs for people with progressive forms of MS appear to be as effective as on-label, or approved, DMTs. He also reads the latest installment of our “Expert Voices” series, where Dr. Susan Payrovi, MD, answers questions about functional medicine care with MS. =================================== Are you interested in learning more about multiple sclerosis? If so, please visit: https://multiplesclerosisnewstoday.com/ ===================================== To join in on conversations regarding multiple sclerosis, please visit: https://multiplesclerosisnewstoday.com/forums/

Whether we adults admit it or not, kids see everything. That includes seeing a parent or other family member who's living with MS. And because kids don't have an understanding of neurological conditions, they use their imaginations to fill in the blanks. That can very quickly take them down a rabbit-hole that's far scarier than the reality of living with MS. So, when do you talk to your kids about MS? And what do you say? Licensed social worker and behavioral specialist Erin Martin joins me to talk about talking to kids about your MS. If you're living with MS and you still smoke, we're sharing results of a study that you may want to carefully consider. We'll also share the results of two different studies that might help inform your COVID-19 strategy if you're on a b-cell depleting disease-modifying therapy. We'll let you know how you can catch the video replay of an excellent webinar presented by the International Progressive MS Alliance. We'll share the details about how a group of international experts discovered a method for measuring remyelinated MS lesions (And we'll tell you why that's become important right now) We'll also share some encouraging results of a study that looked at the impact of estriol and Copaxone on women living with MS. We have a lot to talk about! Are you ready for RealTalk MS??! Talking to kids about MS   :22 Smoking is shown to affect MS progression  1:29 COVID-19 vaccines, breakthrough infections, and Evusheld  3:44 Catch the video replay of the International Progressive MS Alliance Webinar  8:31 A team of international experts discover a way to measure myelin repair  9:08 Combination of Estriol plus Copaxone is shown to reduce neurofilament light chain levels  11:57 Behavioral specialist Erin Martin discusses talking about MS with your kids  14:27 Share this episode  29:03 Download the RealTalk MS app for your iOS or Android device   29:24 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/254 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com National MS Society COVID-19 Vaccine Guidance for People Living with MS https://www.nationalmssociety.org/coronavirus-covid-19-information/multiple-sclerosis-and-coronavirus/covid-19-vaccine-guidance STUDY: The Effect of Smoking on Long-Term Grey Matter Atrophy and Clinical Disability in Patients with Relapsing-Remitting Multiple Sclerosis https://nn.neurology.org/content/9/5/e200008 STUDY: Tixagevimab and Cligavimab (Evusheld) Boost Antibody Levels to SARS-COV2 in Patients with Multiple Sclerosis on B-Cell Depleters https://sciencedirect.com/science/article/pii/S2211034822004163 VIDEO: Solving the Mystery of Progression: The Key to New Treatments for Progressive MS https://youtube.com/watch?v=U5sm54HSBpY STUDY: A New Advanced MRI Biomarker for Remyelinated Lesions in Multiple Sclerosis https://onlinelibrary.wiley.com/doi/10.1002/ana.26441 STUDY: Decreased Neurofilament Light Chain Levels in Estriol-Treated Multiple Sclerosis https://onlinelibrary.wiley.com/doi/10.1002/acn3.51622 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 254 Guest: Erin Martin Tags: MS, MultipleSclerosis, MSResearch, MSSociety, RealTalkMS Privacy Policy

Jon Strum's wife, Jeanne, was an avid biker, hiker, and writer when she was diagnosed with Progressive MS. Almost immediately, she became so severely disabled that Jon stopped working and became Jeanne's carer and advocate. He continued in this role until Jeanne passed in February 2020. Part of Jon's advocacy was (and continues to be) hosting the popular RealTalk MS podcast. As you'll hear, Jon started the podcast while sitting on a scientific committee as a member of the International Progressive MS Alliance, to bridge the gap between patients and caregivers and the scientific community. Since its launch in 2017 and over 200 episodes later it has been downloaded more than 1,000,000 times by listeners in over 100 countries around the world.Jon's devotion to his wife is moving and unquestionable. But so is his desire and commitment to advocating for all people living with Multiple Sclerosis.Listen in to my interview with this wonderful man and find out about all the ways that you can advocate for people with MS and affect change!Topics covered in this episode include:The story of Jeanne's diagnosis, and Jon's journey into caregiving and advocacyJon and Jeanne's experiences with health insurance, the impact on their finances, and the heartbreaking decision Jon had to make for Jeanne's care Why Jon feels that people with more progressive forms of MS can feel forgotten by the scientific community, and why he started the RealTalk MS PodcastJon's partnership with the National MS SocietyThings that are on the legislative horizon for people in the US with MS, and how you can get involved and put pressure on your representatives!Full show notes and resources at https://fumsnow.com/fums109/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Multiple Sclerosis News Today's multimedia associate, Price Wooldridge, reads a news article about how people with progressive forms of multiple sclerosis, and those with greater MS-related disability, have a much higher risk of serious infections. He also reads “Hoping for Medical Debt Relief? This Nonprofit Just Might Help”, by Ed Tobias, from his column "The MS Wire.” =================================== Are you interested in learning more about multiple sclerosis? If so, please visit: https://multiplesclerosisnewstoday.com/ ===================================== To join in on conversations regarding multiple sclerosis, please visit: https://multiplesclerosisnewstoday.com/forums/

A decade ago, the International Progressive MS Alliance didn't exist. Today, it can be credited with changing the global conversation about progressive MS research, elevating the progressive MS research agenda and moving the work forward. A few weeks ago, the Alliance announced the details of an ambitious strategic plan that will guide their work over the next 3 years.  Joining me to talk about the new goals that were set by the Alliance, and what that means for people affected by progressive MS, is the Chair of the Alliance's Scientific Steering Committee, Dr. Robert Fox. The MS International Federation conducted a survey and we're wondering whether the responses have raised a larger question? We're also talking about a study that showed how an online mindfulness program significantly improved depression for people living with MS. We're sharing study results that show your nose knows when your DMT is working well for you. We'll also share the details about an exciting undertaking at the University of Colorado that may lead to treating people so that they completely avoid the symptoms of MS. And we'll tell you about a small trial that demonstrated the effectiveness of an experimental stem cell therapy as a potential treatment for progressive MS. We have a lot to talk about! Are you ready for RealTalk MS??! International Progressive MS Alliance unveils a new 3-year strategic plan  :22 Survey results raise a larger question -- How do we share MS research news with people affected by MS???  1:04 Online mindfulness provides significant improvement for managing depression among people with MS    16:14 Using your nose to determine the efficacy of your disease-modifying therapy  8:33 NeuroGenesis cell therapy shows promise as a potential treatment for progressive MS  14:14 Dr. Robert Fox discusses what's next for the International Progressive MS Alliance  17:28 Share this episode  28:07 Have you downloaded the RealTalk MS app?   28:27 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/239 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jonstrum@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com National MS Society COVID-19 Vaccine Guidance for People Living with MS https://www.nationalmssociety.org/coronavirus-covid-19-information/multiple-sclerosis-and-coronavirus/covid-19-vaccine-guidance International Progressive MS Alliance https://progressivemsalliance.org STUDY: A Randomized Controlled Trial of a Web-Based Mindfulness Programme for People With MS With and Without a History of Recurrent Depression https://journals.sagepub.com/doi/10.1177/13524585211068002 STUDY: Olfactory Threshold Predicts Treatment Response in Relapsing Multiple Sclerosis https://journals.sagepub.com/doi/10.1177/1354285221079744 STUDY: Effects of Mesenchymal Stem Cell Transplantation on Cerebrospinal Fluid Biomarkers in Progressive MS https://academic.oup.com/stcltm/article/11/1/55/6528889 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 239 Guests: Dr. Robert Fox Tags: MS, MultipleSclerosis, MSResearch, MSSociety, RealTalkMS Privacy Policy

I'm delighted that my guests today are Tamara Kahn and Terry Hord, twin sisters who both have MS. Following their diagnosis, they have been navigating their lives with secondary Progressive MS and advocating through work for the National MS Society, their Twins Coast 2 Coast website, and on Instagram.In the first of a two-part interview, they talk about being diagnosed with the same chronic illness, married life, changes they've seen in Disease Modifying Therapies, and how their advocacy work is inspired by their mother's death from a rare form of cancer. The resilience she showed is a legacy that lives on, not only through Tamara and Terry but their own children. Links and resources:Visit Tamara and Terry at Twins Coast 2 CoastVisit the National MS Society and find out more about the Navigator Program You can find Kathy Chester atdisruptfitnessgym@gmail.com moveitorloseit109@gmail.com Instagram - @msmoveitorloseit @disruptfitnessgymHere are some additional products that help Kathy deal with beating the Heat and Migraines.  Take advantage of the coupon code.Koldtec - Cool Head WrapKOLD10To save $10 off every item in store.2 items = $20 savings3 items = $30 savingshttps://www.koldtec.com/ Cold bean bag Releafpack. 15% discount use code Disrupt15https://www.releafpack.com 

Multiple Sclerosis News Today's multimedia associate, Price Wooldridge, discusses how Immunic Therapeutics has enrolled a patient in the Phase 2 clinical trial CALLIPER, testing oral IMU-838 for progressive MS; and reads the column by Ed Tobias, MS Wire, “Sun-seeking Finds Support in New Study.” =================================== Are you interested in learning more about multiple sclerosis? If so, please visit: https://multiplesclerosisnewstoday.com/ ===================================== To join in on conversations regarding multiple sclerosis, please visit: https://multiplesclerosisnewstoday.com/forums/

Join me as I have a candid conversation with my brother, Greg Dukes who has been living with progressive MS-multiple sclerosis for 13 years ..A disease of the central nervous system that disrupt the flow of information within the brain and body. The cause is still unknown! www.nationalmssociety.com 1-800-344-4867 Thank you for listening …this is purple mom, What does live in a juicy lifestyle look like for you? #lifelessonslearned #letgoletgod #ms #advocate #disease #brainhealth #guthealth #lifestyle #family #brother A Huge Thank You Can …Debbie Gregory Nicole my family support, love Greg

Multiple Sclerosis News Today's columnist, Jenn Powell, discusses a phase 2 clinical trial in which NurOwn's cell therapy for progressive MS has been found safe and effective. Also, Multiple Sclerosis News Today's columnist, Jessie Ace reads Jenn Powell's column where she discusses how to manifest change with secondary progressive multiple sclerosis. ===================================== Treatment for Relapsing MS Progression | MAYZENT® (siponimod) Read about MAYZENT, a once daily pill that can significantly slow down disability progression in people with relapsing MS. See full prescribing & safety info. https://www.mayzent.com/?utm_source=changeinrms&utm_medium=vanityurl&utm_campaign=novartis_mayzent_2020&utm_content=soundcloud ===================================== Are you interested in learning more about multiple sclerosis? If so, please visit: https://multiplesclerosisnewstoday.com/ ===================================== To join in on conversations regarding multiple sclerosis, please visit: https://multiplesclerosisnewstoday.com/forums/

Multiple Sclerosis News Today's columnist, Jenn Powell, discusses how the Progressive MS Alliance wants changes to trials to better realize treatments. Multiple Sclerosis News Today's columnist, Jessie Ace reads Jennifer Powell's column about how she is coping going through life battling with sickness and sadness. ===================================== Treatment for Relapsing MS Progression | MAYZENT® (siponimod) Read about MAYZENT, a once daily pill that can significantly slow down disability progression in people with relapsing MS. See full prescribing & safety info. https://www.mayzent.com/?utm_source=changeinrms&utm_medium=vanityurl&utm_campaign=novartis_mayzent_2020&utm_content=soundcloud ===================================== Are you interested in learning more about multiple sclerosis? If so, please visit: https://multiplesclerosisnewstoday.com/ ===================================== To join in on conversations regarding multiple sclerosis, please visit: https://multiplesclerosisnewstoday.com/forums/

Can you imagine waking up one day then being diagnosed with a condition that puts you into a wheelchair for the rest of your life? Although, Wikipedia lists Multiple Sclerosis as an incurable disease, today we're here with a remarkable woman who was sentenced to a life in a tilt-recline wheelchair with progressive MS... and went on to defy her diagnosis and reverse her condition with real food and lifestyle intervention. Today, Dr. Terry Wahls bikes to work, speaks all over the country, and teaches others how to heal conditions commonly considered to be untreatable with cutting-edge science and a healthy dollop of good old common sense. Also joining us for this interview is Caroleen Moise, the producer and director of Defying All Odds, a new documentary featuring the story of Dr Terry Wahls' astonishing recovery from Progressive MS. On this show you're going to learn about: The body's remarkable ability to heal itself and defy the odds Why more than a dozen new scientific studies are testing food as medicine The new documentary dedicated to Dr. Wahl's journey from rebel to visionary And tons more… Let's go hang out with Dr. Wahls. Read the full show notes: https://fatburningman.com/dr-terry-wahls-recovering-from-progressive-multiple-sclerosis-with-food-as-medicine/

Can you imagine waking up one day then being diagnosed with a condition that puts you into a wheelchair for the rest of your life? Although, Wikipedia lists Multiple Sclerosis as an incurable disease, today we're here with a remarkable woman who was sentenced to a life in a tilt-recline wheelchair with progressive MS... and went on to defy her diagnosis and reverse her condition with real food and lifestyle intervention. Today, Dr. Terry Wahls bikes to work, speaks all over the country, and teaches others how to heal conditions commonly considered to be untreatable with cutting-edge science and a healthy dollop of good old common sense. Also joining us for this interview is Caroleen Moise, the producer and director of Defying All Odds, a new documentary featuring the story of Dr Terry Wahls' astonishing recovery from Progressive MS. On this show you're going to learn about: The body's remarkable ability to heal itself and defy the odds Why more than a dozen new scientific studies are testing food as medicine The new documentary dedicated to Dr. Wahl's journey from rebel to visionary And tons more… Let's go hang out with Dr. Wahls. Read the full show notes: https://fatburningman.com/dr-terry-wahls-recovering-from-progressive-multiple-sclerosis-with-food-as-medicine/