Podcasts about cibmtr

In this podcast, Dr. Marcos de Lima from the Ohio State University, Columbus, OH, USA, and Dr. David I. Marks from the University Hospitals Bristol NHS Trust, Bristol, UK, discuss real-world data obtained from the Center for International Blood and Marrow Transplant Research database to evaluate post-allogeneic hematopoietic stem cell transplantation outcomes in adult patients with acute lymphoblastic leukemia who received inotuzumab ozogamicin. This podcast is published open access in Targeted Oncology and is fully citeable. You can access the original published podcast article through the Targeted Oncology website and by using this link: https://link.springer.com/article/10.1007/s11523-025-01129-5. All conflicts of interest can be found online. Open Access This podcast is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The material in this podcast is included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

CancerNetwork®, in collaboration with The American Society for Transplantation and Cellular Therapy (ASTCT), organized an X Space hosted by Rahul Banerjee, MD, FACP, an assistant Professor in the Clinical Research Division at the Fred Hutchinson Cancer Center in Seattle, Washington, and Shernan Holtan, MD, the chief of Blood and Marrow Transplantation and professor of Medicine at Roswell Park Comprehensive Cancer Center.  The conversation took place during the 2025 Tandem Meeting and highlighted many significant presentations and posters on CAR T-cell therapies and transplantation, Banerjee's and Holtan's respective areas of expertise. The following trials were discussed: LBA1 - Phase II Multicenter Trial of Idecabtagene Vicleucel (Ide-cel) Followed By Lenalidomide Maintenance for Multiple Myeloma Patients with Sub-Optimal Response after an Upfront Autologous Hematopoietic Cell Transplantation: Top Line Results from the BMT CTN 1902 Clinical Trial1 “This [study] is nice because it merges 2 worlds. It's like a tandem—but not really a tandem—because you're not doing 2 transplants back-to-back. You're doing a transplant followed by CAR T-cell therapy,” said Banerjee. Abstract 50 - CAR T Cell Therapy in Early Relapsed/Refractory Large B-Cell Lymphoma: Real World Analysis from the Cell Therapy Consortium2 “In a relatively small cohort, [investigators] found no difference in 9-month survival whether someone got their [CAR T cells] in second-line therapy vs third-line therapy from a statistical perspective. If you look at the curves, it looks like there is a potential benefit to second-line therapy, but there was not enough statistical power to determine a difference,” said Holtan. Poster 340 - CD83 Expression By Human Breast Cancer Mediates Effective Killing By CAR T3 “If there's a way to do [the therapy] armored and have a paracrine delivered in real time—and not given to the whole body—[so] the patient [would] have all the adverse effects and cytokine release syndrome release on their own…that would be awesome,” stated Banerjee.  Poster 317 - Risk Factors for Immune Effector Cell-Associated Enterocolitis (IEC-colitis) in Patients with Relapsed Myeloma Treated with Ciltacabtagene Autoleucel (cilta-cel)4 “From the best that we can tell, ironically, corticosteroids aren't the fix that we want them to be [for immune effector cell-associated colitis]…We were like ‘Diarrhea, whatever. Let's give some steroids and treat it like gut graft-versus-host-disease,' but these patients [didn't] respond as well [to that],” said Banerjee. Poster 572 - Post-CAR-T Driving Restrictions Appear Unnecessary after Week 4: Data from the US Multiple Myeloma Immunotherapy Consortium5 “Patients and their caregivers [who have] put their life aside for 4 weeks just to get through CAR T-cell therapy and the Risk Evaluation and Mitigation Strategies requirements are now being told ‘You're free to go, but you can't drive for 4 weeks, which means you can't get your own groceries or…go to doctor's appointments by yourself.' Basically, we argue…that this [requirement] is not evidence-based,” stated Banerjee.  Presentation 58 - Physical Function Measures Identify Non-Hodgkin Lymphoma Patients at High Risk of Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) and 1-Year Mortality after Chimeric Antigen Receptor T (CAR-T) Cell Therapy6 “This [presentation] highlights that even within a high [CAR-HEMATOTOX group], those patients were at extraordinarily high risk of not benefitting from CAR T-cell therapy, and these tests are so simple to do. It's going to be interesting to see if others can reproduce this,” said Holtan. Poster 618 - Comparison of Outcomes after Hematopoietic STEM Cell Transplantation (HCT) for Myelodysplastic Syndrome (MDS) Patients Older or Younger THAN 65 YEARS Old. a Retrospective Analysis of the Latin America Registry7 “My personal hope for this space is that our field can come up with more novel conditioning regimens such that we can ablate the marrow without causing those gastrointestinal toxicities or other organ toxicities [while] doing that so effectively that we don't even need maintenance therapies for a lot of conditions,” stated Holtan. Presentation 39 - Determinants of Immune Suppression Discontinuation in the Modern Era: A CIBMTR Analysis of 18,642 Subjects8 “I'm going to make a provocative prediction for the next paper [approximately 10 years from now]. I predict that steroids won't be the first-line therapy for acute or chronic graft-versus-host-disease,” Holtan said. Poster 516 - Patient Experiences with Chronic Graft-Versus-Host Disease and Its Treatment in the United States: A Retrospective Social Media Listening Study9 “We can still work together to make life as good as we possibly can [for patients], to improve physical function, to take away some of this mental distress, and then work together for advocacy too. [We can] help with peer support, help with resources, and help relieve some of that misunderstanding in the community,” stated Holtan. References 1.        Garfall AL, Pasquini MC, Bai L, et al. Phase II multicenter trial of idecabtagene vicleucel (ide-cel) followed by lenalidomide maintenance for multiple myeloma patients with sub-optimal response after an upfront autologous hematopoietic cell transplantation: top line results from the BMT CTN 1902 clinical trial. Presented at: 2025 Transplant and Cellular Therapy Meetings; February 12-15, 2025; Honolulu, HI. Abstract LBA-1. 2.        Rojek AE, Ahmed N, Gomez-Llobell M, et al. CAR T cell therapy in early relapsed/refractory large B-cell lymphoma: real world analysis from the cell therapy consortium. Presented at: 2025 Transplant and Cellular Therapy Meetings; February 12-15, 2025; Honolulu, HI. Abstract 50. 3.        Betts BC, Davilla ML, Linden AM, et al. CD83 expression by human breast cancer mediates effective killing by CAR T. Presented at: 2025 Transplant and Cellular Therapy Meetings; February 12-15, 2025; Honolulu, HI. Poster ID 340. 4.        Chang Lim KJ, Chhabra S, Corraes ADMS, et al. Risk factors for immune effector cell-associated enterocolitis (IEC-colitis) in patients with relapsed myeloma treated with ciltacabtagene autoleucel (cilta-cel). Presented at: 2025 Transplant and Cellular Therapy Meetings; February 12-15, 2025; Honolulu, HI. Poster ID 317. 5.        Banerjee R, Richards A, Khouri J, et al. Post-CAR-T driving restrictions appear unnecessary after week 4: data from the US multiple myeloma immunotherapy consortium. Presented at: 2025 Transplant and Cellular Therapy Meetings; February 12-15, 2025; Honolulu, HI. Poster ID 572. 6.        Herr M, McCarthy P, Jacobsen H, et al. Physical function measures identify non-Hodgkin lymphoma patients at high risk of immune effector cell-associated neurotoxicity syndrome (ICANS) and 1-year mortality after chimeric antigen receptor T (CAR-T) cell therapy. Presented at: 2025 Transplant and Cellular Therapy Meetings; February 12-15, 2025; Honolulu, HI. Presentation ID 58. 7.        Duarte FB, Garcia YDO, Funke VAM, et al. Comparison of outcomes after hematopoietic STEM cell transplantation (HCT) for myelodysplastic syndrome (MDS) patients older or younger THAN 65 YEARS Old. A retrospective analysis of the Latin America registry. Presented at: 2025 Transplant and Cellular Therapy Meetings; February 12-15, 2025; Honolulu, HI. Poster ID 618. 8.        Pidala J, DeFlilipp Z, DeVos J, et al. Determinants of immune suppression discontinuation in the modern era: a CIBMTR analysis of 18,642 subjects. Presented at: 2025 Transplant and Cellular Therapy Meetings; February 12-15, 2025; Honolulu, HI. Presentation ID 39. 9.        Cowden M, Derrien-Connors C, Holtan S, et al. Patient experiences with chronic graft-versus-host disease and its treatment in the United States: A retrospective social media listening study. Presented at: 2025 Transplant and Cellular Therapy Meetings; February 12-15, 2025; Honolulu, HI. Poster ID 516.

Join Dr. Steven Devine, Chief Medical Officer at the National Marrow Donor Program and Executive Lead at the CIBMTR®, as he shares groundbreaking advancements in donor availability, transplant processes, and patient care. Discover how new strategies are expanding access to life-saving treatments, particularly for diverse populations, and learn about the collaborative efforts driving these transformative innovations.

Join Dr. Steven Devine, Chief Medical Officer at NMDP, formerly known as the National Marrow Donor Program or Be the Match, and Executive Lead at the CIBMTR®, as he shares groundbreaking advancements in donor availability, transplant processes, and patient care. Discover how new strategies are expanding access to life-saving treatments, particularly for diverse populations, and learn about the collaborative efforts driving these transformative innovations.

In an episode first reported in 2017, we bring you what may be, maybe the greatest gift one person could give to another. You never know what might happen when you sign up to donate bone marrow. You might save a life… or you might be magically transported across a cultural chasm and find yourself starring in a modern adaptation of the greatest story ever told.One day, without thinking much of it, Jennell Jenney swabbed her cheek and signed up to be a donor.  Across the country, Jim Munroe desperately needed a miracle, a one-in-eight-million connection that would save him. It proved to be a match made in marrow, a bit of magic in the world that hadn't been there before.  But when Jennell and Jim had a heart-to-heart in his suburban Dallas backyard, they realized they had contradictory ideas about where that magic came from. Today, an allegory for how to walk through the world in a way that lets you be deeply different, but totally together. This piece was reported by Latif Nasser.  It was produced by Annie McEwen, with help from Bethel Habte and Alex Overington.Special thanks to Dr. Matthew J. Matasar, Dr. John Hill, Stephen Spellman at CIBMTR, St. Cloud State University's Cru Chapter, and Mandy Naglich.Join Be The Match's bone marrow registry here: https://join.bethematch.orgEPISODE CREDITS: Reported by - Latif NasserProduced by - Annie McEwenwith help from - Bethel Habte, and Alex OveringtonSign-up for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)!Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.Leadership support for Radiolab's science programming is provided by the Gordon and Betty Moore Foundation, Science Sandbox, a Simons Foundation Initiative, and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.

In this JCO Article Insights episode, Alexandra Rojek provides a summary on "Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors" by Schaffer et al published in the Journal of Clinical Oncology July 17th, 2024. TRANSCRIPT Alexandra Rojek: Hello and welcome to JCO Article Insights. I'm your host, Alexandra Rojek, and today we will be discussing an original report published in the October 1st issue of JCO titled, “Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors,” by Shaffer et al. The CIBMTR registry study set out to compare outcomes of patients undergoing allogeneic stem cell transplantation hematologic malignancies by HLA antigen matching status as well as by the type of GVHD prophylaxis regimen received either calcineurin inhibitor-based prophylaxis or post-transplant cyclophosphamide or PTCy. This study included patients reported to CIBMTR from January 2017 to June 2021 with AML, ALL or MDS, and required that they have undergone allotransplant with either a calcineurin inhibitor based so tacro or cyclosporine, GVHD prophylaxis, or PTCy, which included a calcineurin inhibitor or sirolimus with or without MMF and ATG. Matched unrelated donors were defined as an 8 out of 8 HLA match. And mismatched unrelated donors were defined as HLA mismatched at any single locus or 7 out of 8. The primary objective of the study aimed to compare overall survival or OS and GVHD and relapse-free survival (GRFS) within and between matched unrelated donors versus mismatched unrelated donors separated by calcineurin inhibitor versus PTCy based GVHD prophylaxis. GRFS was defined as survival without grade 3 to 4 acute GVHD, moderate to severe chronic GVHD requiring systemic therapy or relapse. 10,025 patients were included from 153 centers, with a median follow up of over 36 months. Mismatched unrelated donor recipients were made up of 22% minority ancestry patients as compared to just 8% of patients receiving a matched unrelated donor allo transplant, showing an enrichment for patients of minority ancestry in the mismatched unrelated donor group. Just under 10% of patients were of minority ancestry in the study overall, reflective of challenges in transplant care for these patients, which may include inferior access to care, fewer available and suitably matched donors, among other factors. 54% of all patients were transplanted for AML and 29% for MDS. 45% of patients received myeloablative conditioning, 25% received regimens containing ATG, and 23% overall received PTCy with either a calcineurin inhibitor or sirolimus as well as MMF. Among patients receiving PTCy, the authors did not find differences in overall survival by degree of HLA matching, whereas among patients receiving calcineurin inhibitor-based prophylaxis, there remained survival differences by HLA matching status. When comparing matched unrelated donor calcineurin inhibitor patients with PTCy matched unrelated donor patients, the PTCy arm had better OS, and the mismatched unrelated donor group who received PTCy had similar OS as well. For GRFS, matched unrelated donor and mismatched unrelated donor PTCy patients had no difference in GRFS, similar to the trend the authors see with overall survival. But these patients also had better GRFS than matched unrelated donor patients receiving calcineurin inhibitor-based prophylaxis. Within each prophylaxis arm, there was no difference in GRFS by HLA matching status. HLA mismatched patients receiving PTCy were less likely to experience GRFS than HLA mismatched patients receiving calcineurin inhibitor-based prophylaxis. The authors saw similar differences in comparative trends when subgrouping patients based on conditioning intensity and additionally did not find differences in GRFS and OS by ATG exposure. When looking at patients with minority ancestry, those patients who received a match unrelated donor or mismatched unrelated donor with PTCy had comparable outcomes to non-Hispanic white patients. Additionally, among minority ancestry patients, there was a significant benefit in both GRFS and OS in the PTCy groups as compared to calcineurin inhibitor-based prophylaxis. When examining other specific toxicities included in the composite GRFS endpoint, such as GVHD rates among PTCy patients, the authors note that patients receiving a matched unrelated donor had similar rates of grade 3 to 4 acute GVHD but lower rates of moderate to severe chronic GVHD requiring systemic therapy. There appears to be signal that among PTCy patients, HLA matching reduced rates of moderate to severe chronic GVHD compared to mismatched unrelated donor patients receiving PTCy. These same trends also held when the authors looked at non relapse mortality with no significant differences within the PTCy groups by HLA matching status but reduced non relapse mortality compared to both calcineur and inhibitor-based groups. However, notably, there was a greater risk of relapse among matched unrelated donor PTCy patients than matched unrelated donor calcineurin inhibitor patients, although this risk was comparable between mismatched unrelated donor patients by type of prophylaxis. The authors note that this has also been observed in other retrospective cohorts and may be confounded by differences in conditioning intensity between these cohorts of matched unrelated donor patients, affecting the risk of relapse. Finally, the authors also evaluate whether expansion of donor search criteria to mismatch donors from full HLA matching would increase availability of young donors from minority ancestry patients, and the study noted striking increases for all subgroups examined. This study fits nicely with the BMT CTN 1703 trial published in the recent past, which has showed the superiority of PTCy with the calcineurin inhibitor and MMF when compared with conventional calcineurin inhibitor based immune prophylaxis for reduced intensity matched related donor and matched unrelated donor allotransplant. Of note, very few patients with one HLA antigen mismatch were enrolled on that study. However, others have shown the feasibility of PTCy in the mismatched unrelated donor setting, which has led to its adoption in practice. Although less than a quarter of patients included in this current study received PTCy overall, the findings clearly are aligned with the BMT CTN 1703 study, which is likely to change clinical practice in the longer term in this field. As the accompanying editorial in JCO, written by Dr. Chakravarty nicely lays out, the differences between this study and the EBMT registry study, also published in this issue of JCO are subtle but worthy of note. While both studies show that mismatched unrelated donor patients had worse OS and GRFS than those receiving matched unrelated donor transplants, and then among matched unrelated donor patients the addition of PTCy improved GRFS and OS, there is discordance between the studies whether the addition of PTCy abrogates the effect of HLA mismatching on GRFS and OS. As this editorial points out, there are strikingly different rates of T cell depletion with ATG between the US and Europe, which may account for differences in comparator arms that lead to this discordance. There are several very exciting clinical trials ongoing that will aim to answer some of these outstanding questions regarding comparisons of PTCy and T cell depletion, which the field eagerly looks forward to reviewing. In summary, this registry study of patients receiving allo transplant with matched unrelated donor or mismatched unrelated donor and calcineurin inhibitor or PTCy based GVHD prophylaxis, most notably shows that for patients who may not have a matched unrelated donor available, the addition of PTCy to a mismatched unrelated donor allo transplant allows for improved outcomes after transplant in toxicities and survival. This is most significant for patients of minority ancestries who usually have fewer matched unrelated donors available in registry searches. Improving the transplant options available to these groups of patients is of critical importance in improving equitable access to care for all of our patients. And this study, although retrospective in nature, provides an important understanding of our progress to date and suggests directions for future investigation may indeed be very feasible to continue to close these gaps in care for patients in need of an allo transplant for hematologic malignancies. This is Alexandra Rojek. Thank you for listening to JCO Article Insights. Don't forget to give us a rating or review, and be sure to subscribe so you never miss an episode. You can find all ASCO shows at asco.org/podcasts.   The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.    

In this episode of ASTCT Talks, host Dr. Andrés Gómez De León is joined by Dr. Nandita Khera and Dr. Alexandra Gomez Arteaga to explore the critical issue of disparities and barriers to care in graft-versus-host disease (GVHD). The discussion delves into the factors contributing to unequal access to hematopoietic cell transplantation, such as socioeconomic status, race, and ethnicity, both in the U.S. and globally. The guests highlight initiatives like the ACCESS Initiative by ASTCT and the National Marrow Donor Program, aimed at addressing these disparities through advocacy, awareness, and training for junior faculty. They also discuss the importance of caregiver support, clinical trial accessibility, and the broader impacts of GVHD on patients' lives. Tune in to gain valuable insights into ongoing efforts to promote equitable access to life-saving treatments. About Dr. Nandita Khera Nandita Khera is a Professor of Medicine in the Mayo Clinic College of Medicine and a Consultant in the Division of Hematology/ Oncology at Mayo Clinic Arizona. She treats patients with hematological malignancies and some solid tumors, especially those needing blood and marrow transplant/cell therapy (BMT/CT). Her research focuses on improving the delivery of care to patients with cancer including those undergoing BMT/CT to help them be better prepared for the psychosocial and financial consequences of the treatment. She has published several papers in outcomes, late effects, and quality of care in cancer patients and provides mentorship to trainees interested in projects in these areas. She has been a member and has held leadership positions at Mayo Clinic and in the various committees in organizations/ societies in hematology and BMT/CT.. She was the working committee co-chair for the Health Services and International Issues Working committee of CIBMTR from 2015 to 2020 and a member of BMT-CTN SOSS Late Effects committee in 2020. As the co-chair of Dissemination and Implementation committee at BMT CTN currently, she leads efforts in improving translation of evidence into practice in the field of BMT. She is the Director of Community or Clinical Practice at ASTCT. About Dr. Alexandra Gomez Arteaga Dr. Alexandra Gomez Arteaga is an Assistant Professor at Weill Cornell Medicine/NewYork-Presbyterian Hospital and directs the Allogeneic Bone Marrow Transplant Service and the Advanced Fellowship in Bone Marrow Transplantation. She earned her MD from Los Andes University, completed her residency at the University of Miami, her Hematology/Oncology fellowship at Weill Cornell, and her BMT advanced fellowship at Memorial Sloan Kettering Cancer Center. Dr. Gomez's research focuses on improving outcomes in allogeneic stem cell transplantation for leukemia and myeloid malignancies, with an emphasis on young adults and alternative donors. Her work also addresses the critical need to decrease disparities in access to transplantation for minority populations, a cause she champions across her clinical practice, research, and advocacy. She currently serves as the Co-Chair for the Junior Faculty Initiative within the ASTCT ACCESS Initiative. About Dr. Andrés Gómez De León Dr. Andrés Gómez De León (@GomezDLeonMD) is an Associate Professor at Universidad Autonoma de Nuevo Leon in Monterrey Mexico and an ASTCT Content Committee member with an interest in acute leukemias and transplant and cell therapies in low and middle income countries.

A surprising University of Minnesota study of stem cell transplants found that cancer patients were more likely to die if the cells they received came from donors who lived in poverty or low socioeconomic neighborhoods. We talked to Steve Spellman, vice president of research with NMDP and Senior Scientific Director, CIBMTR and Clinical Services - going over some of the details of this, what NMDP is working on with their research and much more!

Jason helps raise money to fight blood cancer by auctioning off an Executive Suite package at the Four Seasons in Minneapolis. Check out General Manager Florian Riedel describing what you get. Plus he auctions off "Cakes for a Year" from Cafe Latte. And he talks with NMDP Vice President of CIBMTR and Clinical Heather Stefanski about why this auction is so important!

In this latest episode of ASTCT Talks, Dr. Andrés Gómez De León, a physician at the Universidad Autónoma de Nuevo León Hematology Service in Monterrey, Mexico, and Dr. Cristóbal Frutos, who is the Coordinator for the Bone Marrow transplant Unito the Hospital Central Instituto de Previsión Social in Asunción Paraguay, discuss the current state of transplant activities and the importance of having access to cell therapies worldwide. Dr. Frutos presented on this topic during the 2022 Tandem Meetings of ASTCT & CIBMTR.

In the first episode of ASTCT's Titans of Transplant series, Dr. Jennifer Holter-Chakrabarty, physician with The University of Oklahoma Health and professor of medicine in hematology/oncology, speaks with Dr. Mary Horowitz, whose credentials include professor and deputy cancer center director at the Medical College of Wisconsin; the Robert A. Uihlein, Jr. Chair in hematologic research; associate director of genomics; and scientific director emeritus of CIBMTR. The Titans of Transplant series seeks to recognize, celebrate and chronicle the physicians, researchers, pharmacists, nurses, social workers and more who were on the frontlines of the early days of transplant.

陆道培 中国工程院院士，北京大学与复旦大学教授，前中华医学会副主席，前北京大学血液病研究所所长，中华医学会血液学分会名誉主席，中华造血干细胞合作组发起人，中华骨髓库专家委员会名誉主任委员，陆道培医疗集团创始人。 陆道培院士擅长重症血液病实验研究及临床治疗，1981年率先在中国成功完成异基因造血干细胞移植手术，1992年参与筹建“中国非血缘关系骨髓移植供者资料检索库”（中华骨髓库前身），开创并推进了我国造血干细胞移植事业。 1996年，陆道培当选中国工程院院士。 陆道培院士是我国造血干细胞移植的奠基人与不断推动者，促进了造血干细胞移植事业在我国的迅速发展。并且首先证明硫化砷类药物对急性早幼粒细胞白血病有卓效；在国际上进行了首例异基因骨髓移植治愈无丙种球蛋白血症。现已发表文章420余篇/部论著，包括主编《白血病治疗学》等4部专著，参与编写19部著作。 2002年，陆道培院士当选亚洲血液学会（AHA）副主席，并被国际血液学会（ISH）推举为第11届国际血液学会（ISH-APD）2007年大会主席。曾荣获国家科学技术进步二等奖、中华医学会科技进步二等奖、北京市科技进步一等奖等多项重大奖励，还曾荣获何梁何利奖和陈嘉庚奖。并荣获国际骨髓移植研究中心（CIBMTR）授予的2016年杰出的贡献与服务奖，是我国目前唯一的荣获此奖者。（陆道培院士简介来自陆道培医疗集团官网、中国工程院官网，深表感谢！）

陆道培 中国工程院院士，北京大学与复旦大学教授，前中华医学会副主席，前北京大学血液病研究所所长，中华医学会血液学分会名誉主席，中华造血干细胞合作组发起人，中华骨髓库专家委员会名誉主任委员，陆道培医疗集团创始人。 陆道培院士擅长重症血液病实验研究及临床治疗，1981年率先在中国成功完成异基因造血干细胞移植手术，1992年参与筹建“中国非血缘关系骨髓移植供者资料检索库”（中华骨髓库前身），开创并推进了我国造血干细胞移植事业。 1996年，陆道培当选中国工程院院士。 陆道培院士是我国造血干细胞移植的奠基人与不断推动者，促进了造血干细胞移植事业在我国的迅速发展。并且首先证明硫化砷类药物对急性早幼粒细胞白血病有卓效；在国际上进行了首例异基因骨髓移植治愈无丙种球蛋白血症。现已发表文章420余篇/部论著，包括主编《白血病治疗学》等4部专著，参与编写19部著作。 2002年，陆道培院士当选亚洲血液学会（AHA）副主席，并被国际血液学会（ISH）推举为第11届国际血液学会（ISH-APD）2007年大会主席。曾荣获国家科学技术进步二等奖、中华医学会科技进步二等奖、北京市科技进步一等奖等多项重大奖励，还曾荣获何梁何利奖和陈嘉庚奖。并荣获国际骨髓移植研究中心（CIBMTR）授予的2016年杰出的贡献与服务奖，是我国目前唯一的荣获此奖者。（陆道培院士简介来自陆道培医疗集团官网、中国工程院官网，深表感谢！）

陆道培 中国工程院院士，北京大学与复旦大学教授，前中华医学会副主席，前北京大学血液病研究所所长，中华医学会血液学分会名誉主席，中华造血干细胞合作组发起人，中华骨髓库专家委员会名誉主任委员，陆道培医疗集团创始人。 陆道培院士擅长重症血液病实验研究及临床治疗，1981年率先在中国成功完成异基因造血干细胞移植手术，1992年参与筹建“中国非血缘关系骨髓移植供者资料检索库”（中华骨髓库前身），开创并推进了我国造血干细胞移植事业。 1996年，陆道培当选中国工程院院士。 陆道培院士是我国造血干细胞移植的奠基人与不断推动者，促进了造血干细胞移植事业在我国的迅速发展。并且首先证明硫化砷类药物对急性早幼粒细胞白血病有卓效；在国际上进行了首例异基因骨髓移植治愈无丙种球蛋白血症。现已发表文章420余篇/部论著，包括主编《白血病治疗学》等4部专著，参与编写19部著作。 2002年，陆道培院士当选亚洲血液学会（AHA）副主席，并被国际血液学会（ISH）推举为第11届国际血液学会（ISH-APD）2007年大会主席。曾荣获国家科学技术进步二等奖、中华医学会科技进步二等奖、北京市科技进步一等奖等多项重大奖励，还曾荣获何梁何利奖和陈嘉庚奖。并荣获国际骨髓移植研究中心（CIBMTR）授予的2016年杰出的贡献与服务奖，是我国目前唯一的荣获此奖者。（陆道培院士简介来自陆道培医疗集团官网、中国工程院官网，深表感谢！）

Go online to PeerView.com/JHF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This PeerView CME-certified activity, which is based on a live symposium held adjunct to the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, features expert guidance on the rapidly changing clinical landscape in multiple myeloma (MM), grounding the recent changes in myeloma care squarely within the context of current recommendations for transplant-eligible patients. Each scientific session explores new data with next-generation proteasome inhibitors and immunomodulatory agents, established and emerging antibodies, cell-based therapy, and newer intracellularly targeted options for ASCT-eligible populations, and includes clinical “take homes” designed to capture the major implications of the evidence presented. Upon completion of this activity, participants should be better able to: Cite current practice recommendations for transplant eligibility, minimal residual disease monitoring, and the role of novel therapeutic platforms in the setting of multiple myeloma, Discuss evidence related to the efficacy and safety of novel therapeutic platforms based on next-generation proteasome inhibitors, immunomodulatory drugs, novel antibodies, and new therapeutic drug classes in conjunction with autologous stem cell transplantation (ASCT) in the management of patients with multiple myeloma, Recommend optimized induction and post-ASCT maintenance/consolidation regimens for eligible patients with multiple myeloma, Develop novel therapeutic platforms for the management of relapsed multiple myeloma post-ASCT, including in the setting of early relapse or treatment-refractory disease.

Go online to PeerView.com/JHF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This PeerView CME-certified activity, which is based on a live symposium held adjunct to the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, features expert guidance on the rapidly changing clinical landscape in multiple myeloma (MM), grounding the recent changes in myeloma care squarely within the context of current recommendations for transplant-eligible patients. Each scientific session explores new data with next-generation proteasome inhibitors and immunomodulatory agents, established and emerging antibodies, cell-based therapy, and newer intracellularly targeted options for ASCT-eligible populations, and includes clinical “take homes” designed to capture the major implications of the evidence presented. Upon completion of this activity, participants should be better able to: Cite current practice recommendations for transplant eligibility, minimal residual disease monitoring, and the role of novel therapeutic platforms in the setting of multiple myeloma, Discuss evidence related to the efficacy and safety of novel therapeutic platforms based on next-generation proteasome inhibitors, immunomodulatory drugs, novel antibodies, and new therapeutic drug classes in conjunction with autologous stem cell transplantation (ASCT) in the management of patients with multiple myeloma, Recommend optimized induction and post-ASCT maintenance/consolidation regimens for eligible patients with multiple myeloma, Develop novel therapeutic platforms for the management of relapsed multiple myeloma post-ASCT, including in the setting of early relapse or treatment-refractory disease.

Go online to PeerView.com/JHF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This PeerView CME-certified activity, which is based on a live symposium held adjunct to the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, features expert guidance on the rapidly changing clinical landscape in multiple myeloma (MM), grounding the recent changes in myeloma care squarely within the context of current recommendations for transplant-eligible patients. Each scientific session explores new data with next-generation proteasome inhibitors and immunomodulatory agents, established and emerging antibodies, cell-based therapy, and newer intracellularly targeted options for ASCT-eligible populations, and includes clinical “take homes” designed to capture the major implications of the evidence presented. Upon completion of this activity, participants should be better able to: Cite current practice recommendations for transplant eligibility, minimal residual disease monitoring, and the role of novel therapeutic platforms in the setting of multiple myeloma, Discuss evidence related to the efficacy and safety of novel therapeutic platforms based on next-generation proteasome inhibitors, immunomodulatory drugs, novel antibodies, and new therapeutic drug classes in conjunction with autologous stem cell transplantation (ASCT) in the management of patients with multiple myeloma, Recommend optimized induction and post-ASCT maintenance/consolidation regimens for eligible patients with multiple myeloma, Develop novel therapeutic platforms for the management of relapsed multiple myeloma post-ASCT, including in the setting of early relapse or treatment-refractory disease.

Go online to PeerView.com/JHF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This PeerView CME-certified activity, which is based on a live symposium held adjunct to the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, features expert guidance on the rapidly changing clinical landscape in multiple myeloma (MM), grounding the recent changes in myeloma care squarely within the context of current recommendations for transplant-eligible patients. Each scientific session explores new data with next-generation proteasome inhibitors and immunomodulatory agents, established and emerging antibodies, cell-based therapy, and newer intracellularly targeted options for ASCT-eligible populations, and includes clinical “take homes” designed to capture the major implications of the evidence presented. Upon completion of this activity, participants should be better able to: Cite current practice recommendations for transplant eligibility, minimal residual disease monitoring, and the role of novel therapeutic platforms in the setting of multiple myeloma, Discuss evidence related to the efficacy and safety of novel therapeutic platforms based on next-generation proteasome inhibitors, immunomodulatory drugs, novel antibodies, and new therapeutic drug classes in conjunction with autologous stem cell transplantation (ASCT) in the management of patients with multiple myeloma, Recommend optimized induction and post-ASCT maintenance/consolidation regimens for eligible patients with multiple myeloma, Develop novel therapeutic platforms for the management of relapsed multiple myeloma post-ASCT, including in the setting of early relapse or treatment-refractory disease.

Go online to PeerView.com/JHF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This PeerView CME-certified activity, which is based on a live symposium held adjunct to the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, features expert guidance on the rapidly changing clinical landscape in multiple myeloma (MM), grounding the recent changes in myeloma care squarely within the context of current recommendations for transplant-eligible patients. Each scientific session explores new data with next-generation proteasome inhibitors and immunomodulatory agents, established and emerging antibodies, cell-based therapy, and newer intracellularly targeted options for ASCT-eligible populations, and includes clinical “take homes” designed to capture the major implications of the evidence presented. Upon completion of this activity, participants should be better able to: Cite current practice recommendations for transplant eligibility, minimal residual disease monitoring, and the role of novel therapeutic platforms in the setting of multiple myeloma, Discuss evidence related to the efficacy and safety of novel therapeutic platforms based on next-generation proteasome inhibitors, immunomodulatory drugs, novel antibodies, and new therapeutic drug classes in conjunction with autologous stem cell transplantation (ASCT) in the management of patients with multiple myeloma, Recommend optimized induction and post-ASCT maintenance/consolidation regimens for eligible patients with multiple myeloma, Develop novel therapeutic platforms for the management of relapsed multiple myeloma post-ASCT, including in the setting of early relapse or treatment-refractory disease.

Go online to PeerView.com/JHF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This PeerView CME-certified activity, which is based on a live symposium held adjunct to the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, features expert guidance on the rapidly changing clinical landscape in multiple myeloma (MM), grounding the recent changes in myeloma care squarely within the context of current recommendations for transplant-eligible patients. Each scientific session explores new data with next-generation proteasome inhibitors and immunomodulatory agents, established and emerging antibodies, cell-based therapy, and newer intracellularly targeted options for ASCT-eligible populations, and includes clinical “take homes” designed to capture the major implications of the evidence presented. Upon completion of this activity, participants should be better able to: Cite current practice recommendations for transplant eligibility, minimal residual disease monitoring, and the role of novel therapeutic platforms in the setting of multiple myeloma, Discuss evidence related to the efficacy and safety of novel therapeutic platforms based on next-generation proteasome inhibitors, immunomodulatory drugs, novel antibodies, and new therapeutic drug classes in conjunction with autologous stem cell transplantation (ASCT) in the management of patients with multiple myeloma, Recommend optimized induction and post-ASCT maintenance/consolidation regimens for eligible patients with multiple myeloma, Develop novel therapeutic platforms for the management of relapsed multiple myeloma post-ASCT, including in the setting of early relapse or treatment-refractory disease.

Go online to PeerView.com/JHF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This PeerView CME-certified activity, which is based on a live symposium held adjunct to the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, features expert guidance on the rapidly changing clinical landscape in multiple myeloma (MM), grounding the recent changes in myeloma care squarely within the context of current recommendations for transplant-eligible patients. Each scientific session explores new data with next-generation proteasome inhibitors and immunomodulatory agents, established and emerging antibodies, cell-based therapy, and newer intracellularly targeted options for ASCT-eligible populations, and includes clinical “take homes” designed to capture the major implications of the evidence presented. Upon completion of this activity, participants should be better able to: Cite current practice recommendations for transplant eligibility, minimal residual disease monitoring, and the role of novel therapeutic platforms in the setting of multiple myeloma, Discuss evidence related to the efficacy and safety of novel therapeutic platforms based on next-generation proteasome inhibitors, immunomodulatory drugs, novel antibodies, and new therapeutic drug classes in conjunction with autologous stem cell transplantation (ASCT) in the management of patients with multiple myeloma, Recommend optimized induction and post-ASCT maintenance/consolidation regimens for eligible patients with multiple myeloma, Develop novel therapeutic platforms for the management of relapsed multiple myeloma post-ASCT, including in the setting of early relapse or treatment-refractory disease.

Go online to PeerView.com/JHF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This PeerView CME-certified activity, which is based on a live symposium held adjunct to the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, features expert guidance on the rapidly changing clinical landscape in multiple myeloma (MM), grounding the recent changes in myeloma care squarely within the context of current recommendations for transplant-eligible patients. Each scientific session explores new data with next-generation proteasome inhibitors and immunomodulatory agents, established and emerging antibodies, cell-based therapy, and newer intracellularly targeted options for ASCT-eligible populations, and includes clinical “take homes” designed to capture the major implications of the evidence presented. Upon completion of this activity, participants should be better able to: Cite current practice recommendations for transplant eligibility, minimal residual disease monitoring, and the role of novel therapeutic platforms in the setting of multiple myeloma, Discuss evidence related to the efficacy and safety of novel therapeutic platforms based on next-generation proteasome inhibitors, immunomodulatory drugs, novel antibodies, and new therapeutic drug classes in conjunction with autologous stem cell transplantation (ASCT) in the management of patients with multiple myeloma, Recommend optimized induction and post-ASCT maintenance/consolidation regimens for eligible patients with multiple myeloma, Develop novel therapeutic platforms for the management of relapsed multiple myeloma post-ASCT, including in the setting of early relapse or treatment-refractory disease.

Go online to PeerView.com/WRR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The recent wave of therapeutic innovation in the management of patients with acute myeloid leukemia (AML) has had implications for many different patient populations, including those who are eligible for allogeneic hematopoietic stem cell transplantation (HCT). Most evidence currently supports a management model that includes the use of newer cytotoxic formulations, novel antibodies, and targeted and epigenetic compounds in conjunction with HCT (eg, as newer induction, conditioning, or maintenance strategies). This expert-led activity, based on a live educational MasterClass held during the 2020 Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, explores these new developments and provides insights on the evidence that continues to support the integration of recent therapeutic innovations into the management of transplant-eligible AML populations. This program also features case-based illustrations of how to adapt or refine current induction, conditioning, and post-HCT maintenance protocols by utilizing the wealth of new agents available for patients and clinicians. Upon completion of this activity, participants should be better able to: Cite current guidelines for transplant eligibility and the use of novel therapeutics as induction, pre-transplant conditioning, or post-HCT maintenance for AML, Summarize updated evidence surrounding innovative approaches to induction, conditioning, and maintenance therapy in conjunction with allogeneic HCT in AML, including strategies using newer cytotoxic agents, targeted agents, antibodies, and epigenetic therapies, Recommend evidence-based regimens with novel components as part of a treatment plan that includes allogeneic HCT for patients with AML.

Go online to PeerView.com/WRR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The recent wave of therapeutic innovation in the management of patients with acute myeloid leukemia (AML) has had implications for many different patient populations, including those who are eligible for allogeneic hematopoietic stem cell transplantation (HCT). Most evidence currently supports a management model that includes the use of newer cytotoxic formulations, novel antibodies, and targeted and epigenetic compounds in conjunction with HCT (eg, as newer induction, conditioning, or maintenance strategies). This expert-led activity, based on a live educational MasterClass held during the 2020 Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, explores these new developments and provides insights on the evidence that continues to support the integration of recent therapeutic innovations into the management of transplant-eligible AML populations. This program also features case-based illustrations of how to adapt or refine current induction, conditioning, and post-HCT maintenance protocols by utilizing the wealth of new agents available for patients and clinicians. Upon completion of this activity, participants should be better able to: Cite current guidelines for transplant eligibility and the use of novel therapeutics as induction, pre-transplant conditioning, or post-HCT maintenance for AML, Summarize updated evidence surrounding innovative approaches to induction, conditioning, and maintenance therapy in conjunction with allogeneic HCT in AML, including strategies using newer cytotoxic agents, targeted agents, antibodies, and epigenetic therapies, Recommend evidence-based regimens with novel components as part of a treatment plan that includes allogeneic HCT for patients with AML.

Go online to PeerView.com/WRR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The recent wave of therapeutic innovation in the management of patients with acute myeloid leukemia (AML) has had implications for many different patient populations, including those who are eligible for allogeneic hematopoietic stem cell transplantation (HCT). Most evidence currently supports a management model that includes the use of newer cytotoxic formulations, novel antibodies, and targeted and epigenetic compounds in conjunction with HCT (eg, as newer induction, conditioning, or maintenance strategies). This expert-led activity, based on a live educational MasterClass held during the 2020 Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, explores these new developments and provides insights on the evidence that continues to support the integration of recent therapeutic innovations into the management of transplant-eligible AML populations. This program also features case-based illustrations of how to adapt or refine current induction, conditioning, and post-HCT maintenance protocols by utilizing the wealth of new agents available for patients and clinicians. Upon completion of this activity, participants should be better able to: Cite current guidelines for transplant eligibility and the use of novel therapeutics as induction, pre-transplant conditioning, or post-HCT maintenance for AML, Summarize updated evidence surrounding innovative approaches to induction, conditioning, and maintenance therapy in conjunction with allogeneic HCT in AML, including strategies using newer cytotoxic agents, targeted agents, antibodies, and epigenetic therapies, Recommend evidence-based regimens with novel components as part of a treatment plan that includes allogeneic HCT for patients with AML.

Go online to PeerView.com/WRR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The recent wave of therapeutic innovation in the management of patients with acute myeloid leukemia (AML) has had implications for many different patient populations, including those who are eligible for allogeneic hematopoietic stem cell transplantation (HCT). Most evidence currently supports a management model that includes the use of newer cytotoxic formulations, novel antibodies, and targeted and epigenetic compounds in conjunction with HCT (eg, as newer induction, conditioning, or maintenance strategies). This expert-led activity, based on a live educational MasterClass held during the 2020 Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, explores these new developments and provides insights on the evidence that continues to support the integration of recent therapeutic innovations into the management of transplant-eligible AML populations. This program also features case-based illustrations of how to adapt or refine current induction, conditioning, and post-HCT maintenance protocols by utilizing the wealth of new agents available for patients and clinicians. Upon completion of this activity, participants should be better able to: Cite current guidelines for transplant eligibility and the use of novel therapeutics as induction, pre-transplant conditioning, or post-HCT maintenance for AML, Summarize updated evidence surrounding innovative approaches to induction, conditioning, and maintenance therapy in conjunction with allogeneic HCT in AML, including strategies using newer cytotoxic agents, targeted agents, antibodies, and epigenetic therapies, Recommend evidence-based regimens with novel components as part of a treatment plan that includes allogeneic HCT for patients with AML.

Go online to PeerView.com/WRR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The recent wave of therapeutic innovation in the management of patients with acute myeloid leukemia (AML) has had implications for many different patient populations, including those who are eligible for allogeneic hematopoietic stem cell transplantation (HCT). Most evidence currently supports a management model that includes the use of newer cytotoxic formulations, novel antibodies, and targeted and epigenetic compounds in conjunction with HCT (eg, as newer induction, conditioning, or maintenance strategies). This expert-led activity, based on a live educational MasterClass held during the 2020 Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, explores these new developments and provides insights on the evidence that continues to support the integration of recent therapeutic innovations into the management of transplant-eligible AML populations. This program also features case-based illustrations of how to adapt or refine current induction, conditioning, and post-HCT maintenance protocols by utilizing the wealth of new agents available for patients and clinicians. Upon completion of this activity, participants should be better able to: Cite current guidelines for transplant eligibility and the use of novel therapeutics as induction, pre-transplant conditioning, or post-HCT maintenance for AML, Summarize updated evidence surrounding innovative approaches to induction, conditioning, and maintenance therapy in conjunction with allogeneic HCT in AML, including strategies using newer cytotoxic agents, targeted agents, antibodies, and epigenetic therapies, Recommend evidence-based regimens with novel components as part of a treatment plan that includes allogeneic HCT for patients with AML.

Go online to PeerView.com/WRR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The recent wave of therapeutic innovation in the management of patients with acute myeloid leukemia (AML) has had implications for many different patient populations, including those who are eligible for allogeneic hematopoietic stem cell transplantation (HCT). Most evidence currently supports a management model that includes the use of newer cytotoxic formulations, novel antibodies, and targeted and epigenetic compounds in conjunction with HCT (eg, as newer induction, conditioning, or maintenance strategies). This expert-led activity, based on a live educational MasterClass held during the 2020 Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, explores these new developments and provides insights on the evidence that continues to support the integration of recent therapeutic innovations into the management of transplant-eligible AML populations. This program also features case-based illustrations of how to adapt or refine current induction, conditioning, and post-HCT maintenance protocols by utilizing the wealth of new agents available for patients and clinicians. Upon completion of this activity, participants should be better able to: Cite current guidelines for transplant eligibility and the use of novel therapeutics as induction, pre-transplant conditioning, or post-HCT maintenance for AML, Summarize updated evidence surrounding innovative approaches to induction, conditioning, and maintenance therapy in conjunction with allogeneic HCT in AML, including strategies using newer cytotoxic agents, targeted agents, antibodies, and epigenetic therapies, Recommend evidence-based regimens with novel components as part of a treatment plan that includes allogeneic HCT for patients with AML.

Go online to PeerView.com/WRR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The recent wave of therapeutic innovation in the management of patients with acute myeloid leukemia (AML) has had implications for many different patient populations, including those who are eligible for allogeneic hematopoietic stem cell transplantation (HCT). Most evidence currently supports a management model that includes the use of newer cytotoxic formulations, novel antibodies, and targeted and epigenetic compounds in conjunction with HCT (eg, as newer induction, conditioning, or maintenance strategies). This expert-led activity, based on a live educational MasterClass held during the 2020 Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, explores these new developments and provides insights on the evidence that continues to support the integration of recent therapeutic innovations into the management of transplant-eligible AML populations. This program also features case-based illustrations of how to adapt or refine current induction, conditioning, and post-HCT maintenance protocols by utilizing the wealth of new agents available for patients and clinicians. Upon completion of this activity, participants should be better able to: Cite current guidelines for transplant eligibility and the use of novel therapeutics as induction, pre-transplant conditioning, or post-HCT maintenance for AML, Summarize updated evidence surrounding innovative approaches to induction, conditioning, and maintenance therapy in conjunction with allogeneic HCT in AML, including strategies using newer cytotoxic agents, targeted agents, antibodies, and epigenetic therapies, Recommend evidence-based regimens with novel components as part of a treatment plan that includes allogeneic HCT for patients with AML.

Go online to PeerView.com/WRR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The recent wave of therapeutic innovation in the management of patients with acute myeloid leukemia (AML) has had implications for many different patient populations, including those who are eligible for allogeneic hematopoietic stem cell transplantation (HCT). Most evidence currently supports a management model that includes the use of newer cytotoxic formulations, novel antibodies, and targeted and epigenetic compounds in conjunction with HCT (eg, as newer induction, conditioning, or maintenance strategies). This expert-led activity, based on a live educational MasterClass held during the 2020 Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, explores these new developments and provides insights on the evidence that continues to support the integration of recent therapeutic innovations into the management of transplant-eligible AML populations. This program also features case-based illustrations of how to adapt or refine current induction, conditioning, and post-HCT maintenance protocols by utilizing the wealth of new agents available for patients and clinicians. Upon completion of this activity, participants should be better able to: Cite current guidelines for transplant eligibility and the use of novel therapeutics as induction, pre-transplant conditioning, or post-HCT maintenance for AML, Summarize updated evidence surrounding innovative approaches to induction, conditioning, and maintenance therapy in conjunction with allogeneic HCT in AML, including strategies using newer cytotoxic agents, targeted agents, antibodies, and epigenetic therapies, Recommend evidence-based regimens with novel components as part of a treatment plan that includes allogeneic HCT for patients with AML.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.

Go online to PeerView.com/DYW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In PeerView's latest CME-certified onDemand activity, based on a symposium at the 2020 Transplantation and Cellular Therapy (TCT) Meetings of ASTCT and CIBMTR, experts lead a series of evidence-based “MasterClass” scientific discussions exploring the nuances of VOD risk assessment, diagnosis, and treatment. The experts also share their perspectives on several adult and pediatric patient cases designed to illustrate how clinicians can “follow the evidence” to apply new recommendations for VOD management and overcome the challenges associated with this serious post-transplant complication. Upon completion of this activity, should be better able to: Identify updated risk factors for VOD, modern diagnostic criteria, and clinical markers of disease severity, Confirm a diagnosis of VOD/SOS in adult and pediatric patients, including those presenting with or without organ dysfunction, in the post-HCT setting, Select optimal treatment for patients with VOD/SOS post-HCT, including those patients exhibiting multi-organ dysfunction or rapidly progressive disease, Cite the role of established and emerging therapeutics as pharmacologic prophylaxis for VOD/SOS.