Podcasts about pioneering

Today, I'm joined by Jared Pobre, founder & CEO of Caldera + Lab.   Launched in 2019, Caldera + Lab is revamping men's medicine cabinets with proprietary premium skincare formulas specifically engineered for guys.   In this episode, we discuss building a biotech-driven men's personal care brand.   We also cover:   Targeting the longevity-minded male consumer Prioritizing proprietary R&D over repurposed formulas Developing distribution strategies and hospitality partnerships   Subscribe to the podcast → insider.fitt.co/podcastSubscribe to our newsletter → insider.fitt.co/subscribeFollow us on LinkedIn → linkedin.com/company/fittinsider Caldera + Lab's Website: www.calderalab.com  Amazon: https://www.amazon.com/stores/CalderaLab/page/2A608586-7E58-411C-8057-FFD688968227   -   The Fitt Insider Podcast is brought to you by EGYM. Visit EGYM.com to learn more about its smart workout solutions for fitness and health facilities.   Fitt Talent: https://talent.fitt.co/  Consulting: https://consulting.fitt.co/  Investments: https://capital.fitt.co/    Chapters: (00:00) Introduction (01:08) Jared's background and Caldera + Lab overview (01:33) The evolution of men's skincare since 2016 (03:02) Formulation differences: women's vs. men's skincare (04:32) Custom formulations vs. menu-based co-manufacturing (06:24) Pioneering proprietary ingredients for men (08:00) Building the brand with bootstrapped resources (10:30) Clinical studies and efficacy testing (13:00) Customer acquisition and finding product-market fit (15:30) DTC and Amazon as core distribution channels (17:45) Storytelling and messaging strategy (21:53) Balancing scientific credibility with consumer messaging (23:12) Targeting the longevity-minded male consumer (25:11) Retail expansion strategy and Series A funding (26:15) Country clubs, luxury hotels, and hospitality partnerships (27:26) Product roadmap (28:49) Conclusion  

This week on Sunday Night Teacher Talk, we're unpacking what it really looks like to build a classroom and school culture from the ground up—especially when you're new to the building. CJ shares updates on how shared experiences like lunch invites, Spirit Week, and hallway antics are shaping connection at his new school.Other big topics this week include how to use ChatGPT to streamline grading while still giving meaningful feedback, what to do when group work falls apart, how to scaffold large writing tasks for struggling students, and why you don't need to post the Ten Commandments to live your values in the classroom.As always, we're getting real about the teacher life, student behavior, faith, and showing up with joy—one week at a time.

From exotic options at Jane Street to pioneering liquid staking infrastructure on #Solana, Jito Foundation's Chief Commercial Officer Thomas Uhm is helping bridge TradFi and DeFi.

Welcome to the 4th and final episode from our "Pioneering the Path - a Purpose 8:28 Experience" series. In this episode of Stories from the River, we bring you a special, behind-the-scenes look into what the "Pioneering the Path - a Purpose 8:28 Experience" really felt and looked like for our retail leaders. These key excerpts from the day's sessions give a rare insight into an even deeper level of this immersive retail leadership development day and into Broad River's culture.  Tune in today to hear Bradley Sullivan's discuss how to enroll your team, get their full support and share in the common vision with Vision, Purpose, and Ownership (VPO). Will Luke will share four key time management tips to keep your team running like clockwork. Steve Ramjit's M.A.G.N.E.T. strategy will help you understand how to attract the very best people, and Gabby Cobos will give insight into how to coach them, consistently. Finally, Chris Wright will weigh in with some trade secrets, a secret sauce to success in a showroom.  Each of our presenters gave their talk three times, to various audiences of small groups of their peers, and they also played a role as active audience members for each other's presentations. (See if you can recognize their jereseys!)  This episode truly highlights the spirit of our Memory Makers. With an "Iron sharpens iron" mindset, they strive to learn from and to teach one another, reinforcing that true leadership is about empowering everyone to own the vision and actively shape both their own and Broad River's legacy.   Watch this episode on youtube:  https://youtu.be/4WShHREPMRQ    Visit https://www.storiesfromtheriver.com  for more episodes.   Broad River Retail brought this show to you. Visit https://BroadRiverRetail.com       Follow us on LinkedIn: https://www.linkedin.com/company/broad-river-retail   

Pioneering historian Professor Henry Reynolds is considered one of the nation's leading authorities on the history of Australia's Indigenous people. 

Welcome to the 4th and final episode from our "Pioneering the Path - a Purpose 8:28 Experience" series. In this episode of Stories from the River, we bring you a special, behind-the-scenes look into what the "Pioneering the Path - a Purpose 8:28 Experience" really felt and looked like for our retail leaders. These key excerpts from the day's sessions give a rare insight into an even deeper level of this immersive retail leadership development day and into Broad River's culture.  Tune in today to hear Bradley Sullivan's discuss how to enroll your team, get their full support and share in the common vision with Vision, Purpose, and Ownership (VPO). Will Luke will share four key time management tips to keep your team running like clockwork. Steve Ramjit's M.A.G.N.E.T. strategy will help you understand how to attract the very best people, and Gabby Cobos will give insight into how to coach them, consistently. Finally, Chris Wright will weigh in with some trade secrets, a secret sauce to success in a showroom.  Each of our presenters gave their talk three times, to various audiences of small groups of their peers, and they also played a role as active audience members for each other's presentations. (See if you can recognize their jereseys!)  This episode truly highlights the spirit of our Memory Makers. With an "Iron sharpens iron" mindset, they strive to learn from and to teach one another, reinforcing that true leadership is about empowering everyone to own the vision and actively shape both their own and Broad River's legacy.   Watch this episode on youtube:  https://youtu.be/4WShHREPMRQ    Visit https://www.storiesfromtheriver.com  for more episodes.   Broad River Retail brought this show to you. Visit https://BroadRiverRetail.com       Follow us on LinkedIn: https://www.linkedin.com/company/broad-river-retail   

Today's guest is Gerard Quinn, Vice President of Innovation and Informatics at ICON plc. With over 35 years of experience in clinical research services, ICON is at the forefront of leveraging artificial intelligence to revolutionise the clinical trial process. In this episode, Gerard shares invaluable insights into how AI is reshaping the landscape of clinical trials, emphasising the importance of trust, scalability and evidence of value.Topics include:0:00 From pilot purgatory to scalable, data-driven AI deployment6:53 Focusing on delivering measurable, evidence-based, and trusted AI value10:43 Ensuring leadership buy-in through transparent, stepwise AI development15:54 Why AI adoption requires cultural and process change, not just implementation18:33 How AI accelerates tasks, enhances value and improves patient outcomes22:32 Optimizing trial sites, investigators and contract processes efficiently with AI27:23 How AI evolved from novelty to expectation, requiring careful implementation31:07 Managing AI adoption costs requires defined users and evidence of value35:02 Implementing AI requires strict governance, transparency, and regulatory compliance

In this episode of TechMagic, hosts Cathy Hackl and Lee Kebler explore the fascinating, funny, and sometimes unsettling intersection between humans and machines. From Cathy's “shopping date” with humanoid robot Maximus to Amazon's ambitious plans to automate its warehouses, the hosts unpack how AI and robotics are reshaping work and daily life. They also discuss Samsung's entry into the XR race with the Galaxy headset, the return of Bored Ape Yacht Club's metaverse project, and innovations like direct-to-vinyl recording. With equal parts humour and insight, Cathy and Lee decode how today's emerging technologies are redefining what's possible, and what's still human.Come for the tech and stay for the magic!Cathy Hackl BioCathy Hackl is a globally recognized tech & gaming executive, futurist, and speaker focused on spatial computing, virtual worlds, augmented reality, AI, strategic foresight, and gaming platforms strategy. She's one of the top tech voices on LinkedIn and is the CEO of Spatial Dynamics, a spatial computing and AI solutions company, including gaming. Cathy has worked at Amazon Web Services (AWS), Magic Leap, and HTC VIVE and has advised companies like Nike, Ralph Lauren, Walmart, Louis Vuitton, and Clinique on their emerging tech and gaming journeys. She has spoken at Harvard Business School, MIT, SXSW, Comic-Con, WEF Annual Meeting in Davos 2023, CES, MWC, Vogue's Forces of Fashion, and more. Cathy Hackl on LinkedInSpatial Dynamics on LinkedInLee Kebler BioLee has been at the forefront of blending technology and entertainment since 2003, creating advanced studios for icons like Will.i.am and producing music for Britney Spears and Big & Rich. Pioneering in VR since 2016, he has managed enterprise data at Nike, led VR broadcasting for Intel at the Japan 2020 Olympics, and driven large-scale marketing campaigns for Walmart, Levi's, and Nasdaq. A TEDx speaker on enterprise VR, Lee is currently authoring a book on generative AI and delving into splinternet theory and data privacy as new tech laws unfold across the US.Lee Kebler on LinkedInKey Discussion Topics:00:00 Intro: Welcome to Tech Magic with Cathy Hackl and Lee Kebler01:30 Shopping with Maximus: A Human-Robot Retail Adventure10:35 Amazon's Automation Revolution: 600,000 Jobs Going Robotic18:30 The AI Bubble: Debating the Reality of AGI and Market Hype28:40 Understanding ChatGPT's Limitations and Technical Challenges37:00 Samsung Galaxy XR: A New Player in the XR Hardware Space43:50 Amazon's HUD Glasses and the Future of Spatial Computing50:25 Bored Ape Yacht Club Returns with "Otherside" Metaverse Project54:58 Upcoming Events and a Deep Dive into Vintage Audio Technology Hosted on Acast. See acast.com/privacy for more information.

Tammy grew up in a Christian family dedicated to ministry and education, which for their family meant moving. A lot. By the age of 13, Tammy had moved 32 times, an experience that taught her the value of connection and community. Later in adulthood, after a divorce from an abusive marriage, Tammy also learned the value of vulnerability, and it was the power of these three together that ushered her into post-traumatic growth and transformation.Today, Tammy is sharing her transformation and helping other women experience their own. She's the CEO of Hope Women's Center, a resource and referral center for women and teen girls that has 7 physical centers and 50 mobile centers across the state of Arizona. Fun fact: HWC is considered Arizona's first faith-based, trauma-informed organization, and it was Tammy, Sanghoon, and Michelle who worked collaboratively to create HWC's trauma-informed culture back in 2018. Listen in as the three of them talk about what it looks like to implement trauma-informed procedures, language, and teams in real time - and without a textbook.Find out more about Hope Women's Center at: www.hopewomenscenter.orgTo contact Tammy: tammy@hopewomenscenter.org

Join Ash Penley, CEO of ZOEX Power, in conversation with Gary Fowler, as they explore how wave energy is entering a new era of innovation and sustainability. From transitioning out of offshore oil & gas to developing a modular Wave Energy Converter that tackles marine energy's biggest challenge — cost-efficiency — Ash shares her remarkable journey as a solo founder raising £1.2M and building what could become the next unicorn out of ScotlandInsights You'll Learn:✅ The Evolution of Wave Energy – from concept to commercialization✅ Entrepreneurial Grit – how Ash transitioned from oil & gas to renewables✅ Breaking Barriers – being the only woman founder in global wave energy✅ Building a Clean-Tech Startup in Scotland – hurdles, lessons, and wins✅ Future of Marine Power – where innovation and sustainability intersect✅ AI & Energy – how artificial intelligence could accelerate the industry✅ Women in STEM – inspiring the next generation of innovatorsWhy This Matters:*Wave energy is one of the most underutilized renewable resources with immense potential.*ZOEX Power's modular technology could finally make wave power commercially viable.*Ash's journey highlights resilience, innovation, and diversity in clean-tech leadershipExpert Background:• CEO & Founder of ZOEX Power, developer of a modular Wave Energy Converter• 15 years' experience in Offshore Oil & Gas complex installations• Raised **£1.2M** in early-stage funding for marine energy innovation• The only woman founder in Wave Energy globally• Passionate about sustainable innovation and empowering women in STEM

PODCAST: Donald Dell, Former Chairman at Sportive and considered one of the pioneers and founders of the sports marketing business, and his daughter Alexandra Dell, Founder of Big Sam Productions and award-winning documentary producer, join Sports Business Radio for a conversation. Donald Dell is a well-known sports agent, attorney, and commentator. He was a former US Davis Cup tennis player and undefeated Captain, and was the founder and chairman of sports marketing company, Proserv.  Dell managed the careers of many professional athletes, including Michael Jordan, Patrick Ewing, Ralph Sampson, James Worthy, Joakim Noah, Boomer Esiason, Andy Murray, Pete Sampras, Gabriela Sabatini, Arthur Ashe, Stan Smith, Jimmy Connors, and Tracy Austin, to name a few.  Alexandra Dell is a writer, director, producer who blends her passion for sports with powerful storytelling. She produced a documentary on tennis great Novak Djokovic with seven-time Emmy winner and Oscar nominee Sam Pollard, set to stream on Amazon in January 2026. She's also executive producing a scripted film about tennis legend and civil rights activist Arthur Ashe, with Skydance, Academy Award-winner Kevin Willmott (“BlacKKKansman”), director Elegance Bratton, Ashok Amritraj, CEO of Hyde Park Entertainment, and Warner Music Group.  With LeBron James and Maverick Carter, Alexandra executive produced Who Is Stan Smith? a documentary on the tennis legend and sneaker icon with SpringHill Entertainment. The film premiered at DOC NYC and opened theatrically in 70+ cities. It's currently streaming on ESPN.  This is the first time that Father and Daughter have done a joint podcast interview. LISTEN to Sports Business Radio on Apple podcasts or Spotify podcasts. Give Sports Business Radio a 5-star rating if you enjoy our podcast. Click on the plus sign on our Apple Podcasts page and follow the Sports Business Radio podcast. WATCH Sports Business Radio interviews by going to https://www.youtube.com/@sportsbusinessradiopodcast.Follow Sports Business Radio on Twitter @SBRadio and on Instagram, Threads and Tik Tok @SportsBusinessRadio. This week's edition of Sports Business Radio is presented by MAI Capital – the exclusive financial partner of Sports Business Radio. MAI Capital is a registered investment adviser and wealth management firm unified in purpose to empower clients to simplify, protect, and grow the wealth they work so hard to build.  Founded in 1973, the firm helps clients achieve their vision and goals through objective advice, tailored planning, comprehensive and integrated solutions, and highly personal service. For more information, visit www.mai.capital or MAI's company page on LinkedIn.   #SportsAgent #DonaldDell #AlexandraDell #Documentaries #SportsMarketing Learn more about your ad choices. Visit megaphone.fm/adchoices

This week we continue our Hall of Fame interview series with inductee Sherry Deschaine, who had a hand in coaching almost every women's sport during her time as a Bobcat. Plus, we introduce you to our two new rowing assistant coaches, one of whom is a familiar face here at Bates. All that and more... Interviews this episode: 1:17 -- Matt Coyne, Head Coach, Football 9:38 -- Carmel Crunk '28, Linebacker, Football. (Male Bobcat of the Week) 18:33 -- Anaïs Reneaum '28, Middle Hitter, Volleyball. (Female Bobcat of the Week) 26:31 -- Hannah Fitts '20 and Greta O'Hara, Rowing assistant coaches. 47:32 -- Sherry Deschaine, Pioneering women's head coach for a combined 50-plus sports seasons, Bates Athletics Hall of Fame.

In this episode of Stories from the River, we sit down with three inspiring Broad River Retail General Managers at the end of an impactful day from the Fort Mill, SC, campus where Broad River held its "Pioneering the Path - a Purpose 8:28 Experience" full learning and development day for all of its retail leaders on August 28, 2025. We sit down with Sonya De La Cruz of Hickory; Brett Cary of Asheville; and Seth Logue of Gastonia to explore what makes the company's culture so unique and impactful. Through their personal stories and leadership experiences, they reveal how Broad River's servant-minded leadership approach and people-first values have shaped their careers and their teams. The conversation highlights the power of choosing positivity and leading with purpose, while also emphasizing how vision, planning, and intentional action help drive success. Each retail leader shares how Broad River's senior leadership sets the tone by genuinely investing in every Memory Maker, knowing them by name, supporting their growth, and practicing the culture rather than simply talking about it. Their insights reinforce that success at Broad River is not solely measured by numbers or KPIs, but by elevating people, fostering belief, and building meaningful relationships. This episode is a reminder that the culture at Broad River Retail is alive in daily actions, not slogans on a wall. It paints a vivid picture of a company that dreams boldly, plans thoughtfully, moves with purpose, and grows together as one team. For anyone who values personal development, servant leadership, and the joy of helping others win, this is an inspiring conversation you won't want to miss. Watch the video on YouTube: https://youtu.be/WxeWQ_beD4E  Visit https://www.storiesfromtheriver.com for more episodes.   Broad River Retail brought this show to you. Visit https://BroadRiverRetail.com       Follow us on LinkedIn: https://www.linkedin.com/company/broad-river-retail   

In this episode of Stories from the River, we sit down with three inspiring Broad River Retail General Managers at the end of an impactful day from the Fort Mill, SC, campus where Broad River held its "Pioneering the Path - a Purpose 8:28 Experience" full learning and development day for all of its retail leaders on August 28, 2025. We sit down with Sonya De La Cruz of Hickory; Brett Cary of Asheville; and Seth Logue of Gastonia to explore what makes the company's culture so unique and impactful. Through their personal stories and leadership experiences, they reveal how Broad River's servant-minded leadership approach and people-first values have shaped their careers and their teams. The conversation highlights the power of choosing positivity and leading with purpose, while also emphasizing how vision, planning, and intentional action help drive success. Each retail leader shares how Broad River's senior leadership sets the tone by genuinely investing in every Memory Maker, knowing them by name, supporting their growth, and practicing the culture rather than simply talking about it. Their insights reinforce that success at Broad River is not solely measured by numbers or KPIs, but by elevating people, fostering belief, and building meaningful relationships. This episode is a reminder that the culture at Broad River Retail is alive in daily actions, not slogans on a wall. It paints a vivid picture of a company that dreams boldly, plans thoughtfully, moves with purpose, and grows together as one team. For anyone who values personal development, servant leadership, and the joy of helping others win, this is an inspiring conversation you won't want to miss. Watch the video on YouTube: https://youtu.be/WxeWQ_beD4E  Visit https://www.storiesfromtheriver.com for more episodes.   Broad River Retail brought this show to you. Visit https://BroadRiverRetail.com       Follow us on LinkedIn: https://www.linkedin.com/company/broad-river-retail   

CIRCULÉIRE is pleased to announce the inaugural All-Island Circular Venture Awards. Open to late-stage start-ups and ventures across the island of Ireland, the award is designed to recognise those pioneering the emergence of the circular economy sector by enabling or demonstrating a circular value proposition. The All-Island Circular Venture Awards invites late-stage start-up driving innovation in the circular economy to submit their proposal by 30th October. The call is aimed at ventures with high potential to reshape how materials, components and products are used, reused, remanufactured and regenerated. All-Island Circular Venture Awards The Awards, designed and led by Irish Manufacturing Research (IMR) and funded by the Department of Climate, Energy and the Environment (DCEE), are a new and prestigious initiative that will see shortlisted companies pitch to a high-profile audience of investors, industry leaders, policy makers, and media on 27th November 2025. Finalists will compete for a total prize pool of €10,000, plus 1-to-1 coaching sessions with international experts in entrepreneurship and circular economy. Referring to the awards announcement, Dr Geraldine Brennan, Director of Circular Economy Innovation at Irish Manufacturing Research, said: "Ireland's transition?to a circular economy is not just an environmental imperative - it's a strategic opportunity to unlock innovation, create green jobs, build resilient economies and enable communities to thrive. Pioneering circular ventures represent the bold thinking and collaborative spirit needed to redesign production and consumption system for a regenerative future." Inspired by this potential, CIRCULÉIRE and Irish Manufacturing Research welcome applications from ventures that meet the eligibility criteria. The Awards are an excellent opportunity to pitch to investors and potential partners aligned with the ventures circular mission. The All-Island Circular Venture Awards will take place at ESB Head Office (F27), 27 Fitzwilliam Street Lower, Dublin 2, D02 KT92 on 27th November 2025 at 2-7pm. Additionally, all shortlisted ventures will receive promotional support from IMR's Circular Economy Innovation Unit and will have the opportunity to feature as a case study on CIRCULÉIRE's website and social media channels. The All-Island Circular Venture Awards will be an occasion for networking with like-minded businesses, all-island government representatives and the CIRCULÉIRE's network members. Late-stage start-ups and ventures should submit their applications via Awards Platform (https://circulei.awardsplatform.com/) by 30th October 2025. The eligibility criteria is available on the Awards site: (https://circulei. awardsplatform.com/) by 30th October 2025. The eligibility criteria is available on the Awards site: https://www.circuleire.ie/all island-circular-venture-award 2025. and will be asked to provide evidence of compliance with the eligibility criteria by 10th November 2025. Any enquiries about the application process can be emailed to circuleire@imr.ie. About Irish Manufacturing Research (IMR) IMR partners with industry to demystify emerging technologies, derisk adoption, and deliver real-world impact - helping businesses scale and innovate with confidence. We bridge the gap between technology and business, ensuring companies can harness the latest advancements to drive efficiency, productivity, and sustainability. About CIRCULÉIRE CIRCULÉIRE, Ireland's First Circular Innovation Network, is led by Irish Manufacturing Research (IMR) and funded by the Department of Environment, Climate, and Communications (DECC). It is a dynamic, cross-sectoral public-private network dedicated to advancing circularity in Ireland. Our mission is to demystify, de-risk, and drive circular business model innovation by unlocking the potential of an Irish circular economy. Established in 2020, CIRCULÉIRE has evolved into a multi-million-euro, industry-led national innovation platform. Our n...

26th October, 2025

In Episode 3, “Women surgeons in Asia – Pioneering progress” of the series “Women in Urology: Dare to Thrive”, Dr. Kinju Adhikari (NP) and Dr. Steffi Kar Kei Yuen (HK) share their experiences as pioneering female surgeons in Asia. Dr. Adhikari recounts her path from Nepal to becoming a leading onco-urologist and robotic surgeon in India, while Dr. Yuen reflects on her work at the Chinese University of Hong Kong and the evolving role of women in urology across the region. Together, they discuss the challenges of gender bias, the importance of perseverance and the growing number of women entering surgical specialities.They highlight the vital role of mentorship, collaboration and supportive professional networks in fostering women's progress in medicine. Both speakers emphasise that while representation has improved, barriers such as societal expectations and limited opportunities still exist. Their conversation explores how passion for patient care and clinical excellence can co-exist with advocacy for equality.Through their exchange, the episode celebrates the determination of women surgeons shaping the future of urology in Asia and inspires the next generation to follow their lead with confidence and purpose.For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

Patrick Wood is the CEO of DelphX Capital Markets, pioneering regulated structures that bring Wall Street-grade risk management to digital assets and fixed income. A 25-year markets veteran, he's focused on bridging traditional finance with the future of institutional crypto.Patrick is a seasoned financial markets expert and visionary, with over 25 years of experience transforming the capital markets landscape across North America. As CEO of DCM Inc., Patrick is leading the charge in financial innovation with the world's first Credit Rating Security (QCS), launched in March 2023—a breakthrough designed to bring institutional-grade governance, risk transfer, and return potential to fixed income portfolios.

Patrick Wood is the CEO of DelphX Capital Markets, pioneering regulated structures that bring Wall Street-grade risk management to digital assets and fixed income. A 25-year markets veteran, he's focused on bridging traditional finance with the future of institutional crypto.Patrick is a seasoned financial markets expert and visionary, with over 25 years of experience transforming the capital markets landscape across North America. As CEO of DCM Inc., Patrick is leading the charge in financial innovation with the world's first Credit Rating Security (QCS), launched in March 2023—a breakthrough designed to bring institutional-grade governance, risk transfer, and return potential to fixed income portfolios.

The UK Investor Magazine was thrilled to welcome Dr James Claypole, founder of Ail Arian, to discuss the sustainable printed electronics pioneer's technology and its current funding round.Ail Arian is revolutionising printed electronics with patented, recyclable silver conductive inks that achieve a 94% recovery rate.Find out more about Ail Arian here.The company addresses critical sustainability challenges in the electronics industry—precious metal depletion and stringent environmental regulations—while helping manufacturers drastically cut CO2 emissions and manufacturing waste.Their innovative design-for-recycling approach creates the first circular ecosystem for printed electronics. This enables customers to reduce e-waste, comply with emerging legislation like ESPR and PPWR, and meet ESG commitments.The global conductive inks market, valued at $2.73B in 2023, is projected to reach $3.98B by 2032. Ail Arian has already developed a working MVP with positive early customer feedback and secured key development partnerships through signed MOUs.As a CleanTech StartUp of the Year Finalist 2025, they're positioned to capture market share by selling sustainable silver inks while allocating investment toward R&D and marketing to scale their circular manufacturing solution. Hosted on Acast. See acast.com/privacy for more information.

In this episode of Growth Amplifiers, host Kenny Harper speaks with Jon Neal, founder of the Neal Group, who has helped over a thousand service-based businesses increase their profits by at least 32% annually using his exclusive 'Neal Deal' strategy. Jon shares his backstory and unique approach to business growth, emphasizing the importance of straightforward, conversational advice and client education. He discusses challenges he has faced, insights on the current economic climate, and strategies for sustaining profitability in various industries, including restaurants and construction. Jon offers valuable advice on the benefits of fixed pricing and empathetic client interactions, providing listeners with actionable insights for amplifying their business. 00:00 Welcome to Growth Amplifiers 00:32 Introducing Jon and the Neal Deal Strategy 04:06 Challenges and Lessons in Business 11:51 Navigating the Current Economic Climate 16:28 The Importance of Professional Advice 22:17 Final Thoughts and Parting Advice

Pioneering artist Paul Wong is back in Halifax for a lecture at the Halifax Central Library on October 23rd. The award winning artist spoke with Alex Guye about his career, his most recent exhibit and why he continually pushes the boundaries of interdisciplinary storytelling.

January 2nd 1979 was a cold day in Scotland. The harsh winter snows meant that the crowd at the famed annual missionary “Report Meeting” in Harley Street Gospel Hall, Glasgow, was much smaller than usual. However, those present were to witness something they would never forget. One of the three missionaries to speak that day was Robert Crawford Allison (1911-1979), a very ill man only 9 months from his homecall to heaven. He had just had a major operation, and The post Robert Crawford Allison – Pioneering for 44 Years in Central Africa (29 min) first appeared on Gospel Hall Audio.

Professor Gordon Hamilton Fairley was the UK's first professor of medical oncology but that career, and life, was cut short on the 23rd October 1975 when an IRA bomb exploded under his neighbour's car. So what did the medical world lose on that day when cancer research and treatment lost one of its pioneers?To chat about the legacy of Professor Gordon Hamilton Fairley with Pat was John Crowne, Consultant Medical Oncologist, St Vincent's Hospital.

In this episode of TechMagic, hosts Cathy Hackl (yep, she's back) and Lee Kebler open Pandora's box - the tech edition. This episode's all about navigating tech disruptions and learning to roll with the punches. From the AWS outage and OpenAI's controversial content policies, to Sora's impact on content creation, Pinterest's AI content controls, and Apple's quiet Vision Pro updates, they deep dive into it all! The AI landscape is evolving faster than you can say the word and so are its implications on content, creativity and commerce. Just like Cathy's travels from Singapore to South Africa, your favourite Tech Magic pair are jetsetting into the world of technology, offering a global perspective on where we're heading and the ethical questions we need to address.Cathy Hackl BioCathy Hackl is a globally recognized tech & gaming executive, futurist, and speaker focused on spatial computing, virtual worlds, augmented reality, AI, strategic foresight, and gaming platforms strategy. She's one of the top tech voices on LinkedIn and is the CEO of Spatial Dynamics, a spatial computing and AI solutions company, including gaming. Cathy has worked at Amazon Web Services (AWS), Magic Leap, and HTC VIVE and has advised companies like Nike, Ralph Lauren, Walmart, Louis Vuitton, and Clinique on their emerging tech and gaming journeys. She has spoken at Harvard Business School, MIT, SXSW, Comic-Con, WEF Annual Meeting in Davos 2023, CES, MWC, Vogue's Forces of Fashion, and more.Cathy Hackl on LinkedInSpatial Dynamics on LinkedInLee Kebler BioLee has been at the forefront of blending technology and entertainment since 2003, creating advanced studios for icons like Will.i.am and producing music for Britney Spears and Big & Rich. Pioneering in VR since 2016, he has managed enterprise data at Nike, led VR broadcasting for Intel at the Japan 2020 Olympics, and driven large-scale marketing campaigns for Walmart, Levi's, and Nasdaq. A TEDx speaker on enterprise VR, Lee is currently authoring a book on generative AI and delving into splinternet theory and data privacy as new tech laws unfold across the US.Lee Kebler on LinkedInKey Discussion Topics:[00:00] Intro to TechMagic [01:15] What the Hell AWS? How a Global Outage Caused Chaos[04:30] Going Global: Tech Perspectives from Singapore to South Africa[08:00] OpenAI's Sora 2: Questions of Purpose and Ethics[14:30] Pinterest Takes a Stand Against AI-Generated Content[17:00] OpenAI's Controversial Move into Adult Content[25:30] Apple's Quiet Hardware Updates and Vision Pro Changes[31:00] Gaming Evolution: From Atari to Interactive Documentaries[35:00] Final Thoughts and Future Conference Plans Hosted on Acast. See acast.com/privacy for more information.

In this episode of Stories from the River, host and CEO Charlie Malouf welcomes keynote speaker and author Kristen Hadeed, fresh off her impactful talk at Broad River Retail's “Pioneering the Path - a Purpose 8:28 Experience” leadership event. Kristen opens up about her unexpected journey—accidentally launching the cleaning company Student Maid at just 19, navigating major failures, and discovering her passion for human-centered leadership. What began as a student side-hustle quickly became a laboratory for learning, where she uncovered how trust, communication, and belief in people can transform a culture. Kristen reveals the pivotal conversation with her friend and colleague Monique that ultimately shifted her company's purpose, evolving from her cleaning company Student Maid to a leadership development organization. Her story sets the stage for a larger message: leadership isn't about perfection—it's about courage, connection, and owning our impact. Charlie and Kristen also discuss how she prepares her keynotes, customizing every presentation to the culture and needs of her audience rather than delivering a pre-packaged speech. Together, they unpack themes from her session, including the power of a “resilience résumé,” confronting imposter syndrome, and recognizing fear as a signal that something truly meaningful is on the line. Kristen's vulnerability, humor, and practical wisdom invite Memory Makers to lead with heart, take ownership, and collaborate boldly with courageous conversations. From her first interactions with Broad River, Kristen says she immediately felt the authenticity and electricity of the culture. Part 1 captures that energy—an inspiring conversation about growth, intentional leadership, and the courage to build environments where people can thrive. Come back for part two of this conversation on Thursday! Additional Resources:  Kristen's Leadership Development Company Website - https://www.kristenhadeed.com   Permission to Screw Up by Kristen Hadeed - https://www.amazon.com/Permission-Screw-Up-Learned-Everything/dp/1591848296   The Human Leadership Program by Kristen Hadeed -  https://www.kristenhadeed.com/humanleadershipprogram   Kristen's Original 2012 TED Talk with over 3.3M Views: How to Retire by 20 - https://www.youtube.com/watch?v=JDvoGev5_tk   Kristen Hadeed and Millennials on the Truly Human Leadership podcast: https://feeds.libsyn.com/67290/podcast/ep-19-kristen-hadeed-and-millennials   Kristen Hadeed and Millennials on the Truly Human Leadership on Apple Podcasts: https://podcasts.apple.com/us/podcast/truly-human-leadership/id992577373?i=1000581569564   The War of Art by Steven Pressfield - https://www.amazon.com/War-Art-Through-Creative-Battles/dp/1936891026   The Imposter Phenomenon by Dr. Pauline Rose Clance - https://paulineroseclance.com/impostor_phenomenon.html   Silence the Imposter by Gary Frey - https://www.amazon.com/Silence-Imposter-Weapons-Syndrome/dp/B0CJLLLV61   Combining Ministry and Football: The Unique Path of Pittsburgh Steelers Chaplain Kent Chevalier - https://www.youtube.com/watch?v=UJuLje81LNE   Arthur Brooks - The Power of Teaching, The Arrival Fallacy, The Mad Scientist Profile, Lifting Heavy Weights, & The Two Best Practices To Be Happy - https://podcasts.apple.com/us/podcast/the-learning-leader-show-with-ryan-hawk/id985396258?i=1000725431986     Watch this episode on YouTube: https://youtu.be/XOAGyXo5auw    Visit https://www.storiesfromtheriver.com for more episodes.  Broad River Retail brought this show to you. Visit https://BroadRiverRetail.com      Follow us on LinkedIn: https://www.linkedin.com/company/broad-river-retail  

In this episode of Stories from the River, host and CEO Charlie Malouf welcomes keynote speaker and author Kristen Hadeed, fresh off her impactful talk at Broad River Retail's “Pioneering the Path - a Purpose 8:28 Experience” leadership event. Kristen opens up about her unexpected journey—accidentally launching the cleaning company Student Maid at just 19, navigating major failures, and discovering her passion for human-centered leadership. What began as a student side-hustle quickly became a laboratory for learning, where she uncovered how trust, communication, and belief in people can transform a culture. Kristen reveals the pivotal conversation with her friend and colleague Monique that ultimately shifted her company's purpose, evolving from her cleaning company Student Maid to a leadership development organization. Her story sets the stage for a larger message: leadership isn't about perfection—it's about courage, connection, and owning our impact. Charlie and Kristen also discuss how she prepares her keynotes, customizing every presentation to the culture and needs of her audience rather than delivering a pre-packaged speech. Together, they unpack themes from her session, including the power of a “resilience résumé,” confronting imposter syndrome, and recognizing fear as a signal that something truly meaningful is on the line. Kristen's vulnerability, humor, and practical wisdom invite Memory Makers to lead with heart, take ownership, and collaborate boldly with courageous conversations. From her first interactions with Broad River, Kristen says she immediately felt the authenticity and electricity of the culture. Part 1 captures that energy—an inspiring conversation about growth, intentional leadership, and the courage to build environments where people can thrive. Come back for part two of this conversation on Thursday! Additional Resources:  Kristen's Leadership Development Company Website - https://www.kristenhadeed.com   Permission to Screw Up by Kristen Hadeed - https://www.amazon.com/Permission-Screw-Up-Learned-Everything/dp/1591848296   The Human Leadership Program by Kristen Hadeed -  https://www.kristenhadeed.com/humanleadershipprogram   Kristen's Original 2012 TED Talk with over 3.3M Views: How to Retire by 20 - https://www.youtube.com/watch?v=JDvoGev5_tk   Kristen Hadeed and Millennials on the Truly Human Leadership podcast: https://feeds.libsyn.com/67290/podcast/ep-19-kristen-hadeed-and-millennials   Kristen Hadeed and Millennials on the Truly Human Leadership on Apple Podcasts: https://podcasts.apple.com/us/podcast/truly-human-leadership/id992577373?i=1000581569564   The War of Art by Steven Pressfield - https://www.amazon.com/War-Art-Through-Creative-Battles/dp/1936891026   The Imposter Phenomenon by Dr. Pauline Rose Clance - https://paulineroseclance.com/impostor_phenomenon.html   Silence the Imposter by Gary Frey - https://www.amazon.com/Silence-Imposter-Weapons-Syndrome/dp/B0CJLLLV61   Combining Ministry and Football: The Unique Path of Pittsburgh Steelers Chaplain Kent Chevalier - https://www.youtube.com/watch?v=UJuLje81LNE   Arthur Brooks - The Power of Teaching, The Arrival Fallacy, The Mad Scientist Profile, Lifting Heavy Weights, & The Two Best Practices To Be Happy - https://podcasts.apple.com/us/podcast/the-learning-leader-show-with-ryan-hawk/id985396258?i=1000725431986     Watch this episode on YouTube: https://youtu.be/XOAGyXo5auw    Visit https://www.storiesfromtheriver.com for more episodes.  Broad River Retail brought this show to you. Visit https://BroadRiverRetail.com      Follow us on LinkedIn: https://www.linkedin.com/company/broad-river-retail  

A pivotal European clinical trial of a new electronic eye implant has seen remarkable results.  The study, published in the New England Journal of Medicine, showed 84% of participants were able to read letters, numbers and words using prosthetic vision through an eye that had previously lost its sight due to the untreatable progressive eye condition, geographic atrophy with dry age-related macular degeneration (AMD).  RNIB Connect Radio's Toby Davey was joined by Mahi Muqit, senior vitreoretinal consultant at Moorfields Eye Hospital and the Institute of Ophthalmology at University College London who lead the UK arm of the trial to explain more about the results of the study and the technology used too. There is more information about this new pioneering eye device on the following pages of the Moorfields Eye Hospital website which also includes a link to register on the Moorfields research portal, ROAM which will give you access to current and future research - https://www.moorfields.nhs.uk/about-us/news-and-blogs/news/pioneering-eye-device-restores-reading-vision-to-blind-eyes (Image shows the RNIB Connect Radio logo. On a white background ‘RNIB' written in bold black capital letters and underlined with a bold pink line. Underneath the line: ‘Connect Radio' is written in black in a smaller font)

Garza sits down in-person with Tommy Victor. Vocalist, guitar player & founder of New York, NY heavy metal band PRONG. Also currently the guitar player for DANZIG. https://prongmusic.comSPONSORS: Sweetwater - https://imp.i114863.net/rnrmVB00:00 - Black Sabbath & Heavy Music Influence04:05 - Nearly 40 Years of Prong05:27 - Catholic School07:50 - Nearly Becoming an Accountant12:23 - Working in Radio14:58 - Driving Cabs & Bike Messenger16:50 - Working at CBGBs21:49 - Mean Streets of New York27:44 - 80s Post Punk/Goth29:55 - Getting Into Bass35:57 - Ramones & Downpicking45:39 - Prong Early Days53:25 - Pioneering Groove Metal // Bad Brains56:38 - Riff: Prove Me Wrong58:02 - Experimenting on Albums59:49 - Rude Awakening1:03:37 - Favorite Prong Riffs1:08:26 - Cleansing vs The Cleansing1:11:23 - Hooks & Songwriting1:13:11 - No Lyrics in CD Booklets1:15:10 - Working w/ Glenn Danzig1:25:50 - Dealing w/ Business1:34:31 - Almost Quitting Music1:56:45 - Staying on Top & Inspiration2:04:28 - Tommy's Parents' Feelings on Prong2:07:48 - Running & Exercise2:10:18 - Guitar rundown: Schecter Devil-FR2:14:03 - Guitar Swap2:17:55 - Floyd Rose Tremolo2:20:03 - New Rush Drummer

The Vault is a morning show hosted on Twitter Spaces and YouTube Live on Tuesdays, Wednesdays, and Thursdays at 11:30 am EST. The show focuses on multi-chain communities, emerging protocols, NFTFi, DeFi, Gaming, and, most importantly, collecting digital assets.Adam McBride: https://twitter.com/adamamcbrideJake Gallen: https://twitter.com/jakegallen_Chris Devitte: https://twitter.com/chris_devvEmblem Vault: https://twitter.com/EmblemVaultAgent Hustle: https://x.com/AgentHustleAIMigrate Fun: https://x.com/MigrateFun

Tyler O'Malley is the Vice President of Clinical Affairs, Bioinformatics, and Market Access at Exagen, Inc. Tyler shares his journey in the MedTech industry and discusses Exagen's innovative approaches to autoimmune testing solutions, including cutting-edge diagnostics for lupus and other diseases. With over a decade of experience, Tyler provides insights into the challenges and breakthroughs in the field, highlighting the significance of early diagnosis and personalized treatment, while also discussing the challenges and opportunities in effective leadership during different stages of company growth.   Guest links: https://exagen.com/ Charity supported: Save the Children Interested in being a guest on the show or have feedback to share? Email us at theleadingdifference@velentium.com.  PRODUCTION CREDITS Host & Editor: Lindsey Dinneen Producer: Velentium Medical   EPISODE TRANSCRIPT Episode 066 - Tyler O'Malley [00:00:00] Lindsey Dinneen: Hi, I'm Lindsey and I'm talking with MedTech industry leaders on how they change lives for a better world. [00:00:09] Diane Bouis: The inventions and technologies are fascinating and so are the people who work with them. [00:00:15] Frank Jaskulke: There was a period of time where I realized, fundamentally, my job was to go hang out with really smart people that are saving lives and then do work that would help them save more lives. [00:00:28] Diane Bouis: I got into the business to save lives and it is incredibly motivating to work with people who are in that same business, saving or improving lives. [00:00:38] Duane Mancini: What better industry than where I get to wake up every day and just save people's lives. [00:00:42] Lindsey Dinneen: These are extraordinary people doing extraordinary work, and this is The Leading Difference. Hello, and welcome back to another episode of The Leading Difference podcast. I'm your host, Lindsey, and I am so excited to introduce you to my guest today, Tyler O'Malley. Tyler serves as Associate VP of Clinical Affairs and Market Access at Exagen, Inc., a leader in autoimmune testing solutions. In his role, he oversees clinical trials, bioinformatics, and medical policy development for Exagen's current diagnostic portfolio and pipeline of proprietary solutions. With more than a decade of experience, O'Malley has contributed to more than a dozen clinical trials focusing on clinical validity and utility evidence for autoimmune diagnostics. His expertise is widely recognized with numerous publications in esteemed peer reviewed journals, and notably, he's the first author of one of the largest clinical utility studies in lupus diagnostics. O'Malley graduated from Georgia Gwinnett College with a Bachelor of Science in biology, concentrating in biochemistry. His 11 year career in research and development and medical affairs encompass medical science, education, assay development, and clinical research coordination. Well, welcome to the show, Tyler. I'm so excited to have you here today. [00:02:01] Tyler O'Malley: Thanks, glad to be here. [00:02:02] Lindsey Dinneen: Yeah, absolutely. Well, I would love just starting off by telling us a little bit about yourself, your background, and what led you to MedTech. [00:02:11] Tyler O'Malley: Sure. So, I'm the Vice President of Clinical Affairs, Bioinformatics, and Market Access at Exagen. We're a specialty diagnostics company focused on autoimmune rheumatic diseases. So we develop proprietary testing technology for conditions like lupus, rheumatoid arthritis, Sjogren's disease, as well as many others. And yeah, our focus is trying to find solutions for patients who are dealing with what are many times challenging chronic diseases that can present themselves in very mysterious ways oftentimes. And so, these are challenges that patients have that have, for the most part, gone unsolved for many decades, and so there's a lot of opportunity out there. In terms of, myself, my background, I've been with Exagen for the past 11 and a half years. So I've been doing this for a while now, and I've worked in a couple of different areas within the organization, doing work within the lab assay development, as well as outside the lab doing clinical research, statistical analysis, which led to the bioinformatics role. And then as well as doing some work trying to align our clinical evidence with medical policy for our tests which is the market access role. So, a little bit of everything, but there are some through lines that I assure you do make some sense if you really think about it. [00:03:33] Lindsey Dinneen: Excellent. Excellent. Well, thank you for sharing a little bit about that. There's so much to dive into, but going back a little bit in your story, when you were thinking about careers-- you're a eager high school student ready to embrace college, and you're ready for the next step --is this something that you could have imagined yourself doing or has this always been a passion of yours? Or is this something you kind of found yourself in? [00:03:57] Tyler O'Malley: Not at all. So, no I, so I will say I've always been interested in autoimmunity. So that's always been something that has always piqued my interest, whether I was in high school or college. And so I guess in that sense, it's not a surprise. But the laboratory diagnostics component of it was not something that was on my radar when I was in high school or college. And I guess the journey to Exagen was, after graduating from high school, went and got a bachelor's degree in biology with a biochemistry focus. So, that's sort of my background there. And while I was getting the degree and focusing on biochemistry, I had the opportunity through a resource scholarship at Georgia Tech to work in a graduate lab, which was a really interesting experience where, you know, for a little over a year I had the opportunity to work alongside PhD candidates, postdocs, on a research project that was partially funded and get the experience and understand what it's like to work towards a PhD and what it would look like to kind of go down that path of graduate level research. And I think it had the opposite effect that it was intended to have in that it kind of showed me I didn't want to do that. So, I think in a lot of ways I was happy I had that experience 'cause it showed me before I went down that path that it was something I didn't wanna do. Nothing against it, I guess I wanted to do something that maybe had more of a translational impact, a little bit closer to the patient. And so, finished my degree, and at the time I was living in Georgia, so I finished my degree in Georgia, left and moved out to California, and ended up at Exagen by pure chance through a recruiter. And that was back in 2014, and basically just joined Exagen at the time when it was a smaller company, and grew with the company, and was fortunate enough to have the ability to learn a lot of different functions within the company as it grew, and there were a lot of different things that needed to be done a as the company was growing. And so it, it's been kind of a, an interesting ride since then. [00:06:08] Lindsey Dinneen: Yeah, absolutely. And of course all of those different experiences, I'm sure, have woven their way in, like you said. Sometimes you have to kind of look for that line, but there is one that's, apparent when you look back. So, can you talk a little bit more about the company, what it does, especially in regards to its testing technology, and I'd love to hear about some of the innovation that's just coming out of this incredible organization you're a part of. [00:06:35] Tyler O'Malley: Sure. So our our testing, again, primarily focuses on addressing unmet needs in patients who have autoimmune connective tissue diseases. And specifically we have some proprietary technology around biomarkers that help diagnose systemic lupus. And lupus is kind of the prototypical autoimmune disease in that it can manifest in just about any different way. It can show up in your skin, your heart, your lungs, your kidneys, just about any way you can imagine, and sometimes in multiple different ways. And so in that way, it can be challenging to diagnose 'cause it can look like so many different things. And much of the testing that is used for lupus or has been used traditionally is very antiquated. Antibody tests that were developed many decades ago that have been refined to some extent over the years, but for the most part are not overly sophisticated. So, what Exagen has done over the past 15 or so years is brought forward some technology, that was originally licensed from University of Pittsburgh, looking at measuring a form of the complement system, which is a part of our immune system. It's a very ancient form of our immune system. It's a collection of proteins that come together to help fight off pathogens and help clear debris to keep our our immune system healthy. And what we're able to do is measure essentially the buildup of a complement fragment that builds up on your red blood cells and on your B lymphocytes. And what this does is it gives us a unique ability to detect lupus that's much more sensitive than the conventional means. And what that means, when I say sensitivity, is that it's able to pick up more lupus patients than the conventional testing. So, one way of thinking about this is like, if you have a hundred patients in a room that all have lupus, right? Because they've been assessed by a doctor, they've been clinically diagnosed, and you were to test them, and say your conventional test is 50% sensitive, meaning half of the room would test positive on this test and the other half would test negative. This test that we're talking about here, it would pick up two thirds of the room, right, as opposed to conventional testing, which would pick up fewer patients. So, that's the kind of technology that we're trying to develop here, which is trying to be more inclusive, pick up more patients sooner, give better insights to physicians to combine with their clinical assessments such that patients can get earlier treatments and hopefully stave off some of the more kind of disastrous outcomes of the disease that come with not getting treated soon enough and not getting treated appropriately for their symptoms. [00:09:31] Lindsey Dinneen: Yeah, of course. That's incredibly important and I'm so glad that the company is working to create those solutions, like you said, because previous methods while maybe somewhat useful, are more antiquated at this point. And so it's really important to have these new strides in innovation. So as you're dealing with all of this, I'm sure that there are stories that have come up about real people having impacted lives because of the technology that your company is bringing. Do you have any examples that you could share with us about that? [00:10:05] Tyler O'Malley: Sure. Yeah, there's been a number of individuals that we've had the fortune of meeting over the years. And they come and share the story with our team. We like to bring folks in with, for example, when we bring on new sales team members, we try to bring on a patient just to be able to share their story. So, recently we had an individual, who is connected to someone who works in our organization-- again, just pure chance-- who happened to have a very unique story. So first of all, lupus, for those who don't know, is a condition that primarily affects women. Lupus is a disease that affects women at a ratio of nine to one, nine to one female to male or so, in other words, around 90% of lupus patients are women. But that's not to say that it isn't an issue for that subset of of men that do develop lupus. And in fact, the disease tends to be more severe in that 10% of lupus patients that are men. So this individual who we've had the chance to meet and hear his story, really interesting because he's-- you would never know if you met this guy-- because he's a CrossFit guy. He is probably the healthiest guy you can imagine looking at him. But he went a harrowing journey to get to his diagnosis. And it all started with, relatively -- well, I don't wanna downplay it-- but let's call it "less severe symptoms" like alopecia and rashes, things like this that sort of make you think, "Well, gee, that's strange," or "I wonder what that is all about." And then leading up to much, much more severe symptoms like severe edema and pericarditis that was ultimately life threatening. And ultimately, he was able to get the right testing and get to the right doctors, but it was not a short journey from the time that these symptoms initially presented themselves to the time where he was able to get to the test and to get to the right diagnosis and onto the right treatment. The good news is, he's in a much better place now after finding out what's causing his symptoms and getting to a treatment management plan that works for him and he's even back to getting to an exercise routine that works for him. It's maybe not exactly the same as what it was before, but I mean, that's the thing. Now, you can lead a relatively normal life with lupus. It wasn't that long ago, call it several decades ago, where the mortality rate for lupus was as high as 50% in the first year after diagnosis. Treatment advances have greatly improved that and have changed the lives of people who live with Lupus now, but it used to be a very severe diagnosis. It still is, but it's very manageable now. [00:12:54] Lindsey Dinneen: Wow. Yeah. And so catching it and having that answer to, like you said, really difficult health journey where you're just not sure what's going on. And I really appreciate you talking a little bit about how Lupus looks different and manifests itself differently in different circumstances so it can be difficult to initially diagnose. So I love the fact that the company is focusing on things like that, when caught early can maybe make a huge difference in somebody's life like the gentleman you mentioned. Thank you for sharing about that. So now your own career has been really interesting in that you have gotten to do a lot of different things within the company and learn so much. Now as you've continued to grow with the company, you've, I'm sure, developed a lot of different leadership skills along the way, and I'm curious what it's been like in that sense of your journey to embrace leadership and how do you go about it? What have you found works really well, and maybe what advice would you have for somebody who's a little bit earlier in their career? [00:13:58] Tyler O'Malley: Yeah. Really interesting question. And I, I guess, my experience was, I came into an organization that was, I think at the time, maybe in the entire company was maybe 60, 70 people. So, as you can imagine, it was a very flat organization. I reported directly to the Chief Scientific Officer when I first joined the organization as a relatively low level R&D employee. So that afforded me, I think, a unique opportunity because I was often involved with project planning and discussions that I don't know that you get that opportunity in different types of corporate settings. And I think what has proven very useful in terms of my development, and as I look back and reflect on kind of what's led me here is, I can just recall, so, so many times, especially early on in, in a startup-- which can sometimes be chaotic and there's a lot of moving parts and things are moving fast-- there would be times where I would be in meetings where I wasn't necessarily expected to do very much, I think, or contribute much. And I would just sort of observe, right? And I think there's so much you can learn through not just listening to the conversation, but the body language of the people around the table. The way that people present, the way that people take criticism, the way that they respond. It was almost like a, it was a lesson every day just watching that. And I think where I thrived and maybe added value at times was realizing when people were talking past one another and just, at times, trying to find a way to come into that and say, "Well, right, but did you consider maybe what this person was trying to communicate here?" And, you can't always resolve those sorts of situations, but sometimes you can. And that's really valuable when you can help two individuals get past an impasse like that. So, and I think it helps you build credibility doing that too, being a bridge builder in that sense. And, and I think, that was something I don't know-- whether intuitively or purely by accident, I don't know-- I figured out over time was that, maybe as a young person in your career, sometimes it can be easy to get caught up on sort of the X's and O's of your job, whatever it is that you're doing-- if you're a computer programmer, you're doing bioinformatics or whatever the case may be-- you can get really caught up in the technical skills that you're trying to hone and develop. But there's so many soft skills that you have to build as well at the same time. And there's the relationships that you build, as well, that you don't know when you're gonna need them or when they'll pay off. But things change at organizations and you're glad when you have those relationships when it comes time to need them. [00:16:51] Lindsey Dinneen: Yeah. Absolutely. Yeah. I love your discussion on the idea of being a bridge builder, because I've been thinking a lot about that recently where there's so much unintentional missed communication, just literally just passing by where, one person is saying something, the other person's saying something, and as an outsider, you're able to have a little bit of a distance to go, "Oh, you're kind of saying the same thing, but I'm not sure that you guys realize that, and here's how." Yeah, that translating is a really important skillset and a fun one when you can nail it down. So as you look towards the future of your own career and the company's trajectory, what are some things that you're looking forward to? [00:17:35] Tyler O'Malley: Well, we obviously have a number of exciting pipeline initiatives that bring a lot of energy to me as I think about what we're trying to do going forward. I'm excited about where the company is headed in terms of its trajectory. I've described my time at the company as, even though I've been at the same company for 11 and a half years or so, I really feel like I've worked for three different companies in that time, in that, there was a period of time that was a startup up until the point the company went public. And then there was this time from when the company was public, where we raised a lot of money, there were a lot of expectations and didn't exactly kind of work out exactly as we had hoped. And then there was a leadership change. And now we're sort of in this third phase now where the arrow's pointing up and we have realigned our strategy here and we found a way to be sustainable and to be able to continue to build on something where hopefully we can continue to find interesting technology that's out there. We have an ongoing partnership with, as an example, Johns Hopkins University to try to develop a test to help address lupus nephritis. So this is a particular form of organ manifestation of lupus. It's one of the more common manifestations of lupus, and one of the more devastating forms of lupus, in that almost 50% of lupus patients will have kidney involvement at some point in their disease. And as much as 10 to 20% of patients who do have lupus nephritis will go on to unfortunately develop end stage kidney disease and require dialysis or kidney transplant. So it's obviously life altering and can be, very impactful to individuals. So, to be able to work on something like that and be able to potentially alter the trajectory of someone's life in that way is pretty cool to think about. And, not everyone gets to do that. I mean, it's not that other jobs aren't meaningful, it's just not everyone gets the opportunity to do that kind of thing. And if you can also find joy in what you're doing in your job. I think that's also great too. I mean, it's really cliche, the things people say, and so I won't do it. The whole, like, " If you like what you do, you never work." Believe me, it's work. I do feel like I'm working sometimes, for sure, but I can't complain. I do, for the most part, have fun with what I'm doing. I'm fortunate enough, I have a great team of people, well-- three teams of people-- that I really enjoy working with, and being able to work with people and see them grow and develop and be a part of that is also super rewarding as well too. So, yeah, I'm just, I'm having a lot of fun. [00:20:26] Lindsey Dinneen: Yeah. Excellent. Wonderful. Well, gosh, I'm gonna pivot the conversation just for fun a little bit. Imagine that you were to be offered a million dollars to teach a masterclass on anything you want. Now, this could be within your industry, but it doesn't have to be. What would you choose to teach? [00:20:45] Tyler O'Malley: I think that-- maybe this is kind of fun, probably not-- but I think that ,I don't know why, and it's funny because it's-- I don't even know if this qualifies because I don't even know how I would teach it-- but I think I'm fairly good at guesstimating numbers and it's really useful in that it helps in a lot of different situations to be able to shortcut math. And to be clear, it's not that I'm doing long division in my head or anything like that, but it's, if you can kind of shortcut and get the approximate number, it can be really useful. And it's a nice kind of party trick too kind of thing. Again, I don't know how I would teach it 'cause it's sort of like it's up here, and I don't know how I would externalize that, but yeah, that's something I feel like would be kind of cool to figure out how I could teach that. [00:21:35] Lindsey Dinneen: Absolutely. Yeah. It's a superpower. So it would be very cool to try to then-- you've got this innate ability-- so then to try to break it down into how does somebody else develop the skill sets that you just sort of possess, and go from there. That would be really entertaining. I love it. Great answer. Okay. And then the next question is, how do you wish to be remembered after you leave this world? [00:21:59] Tyler O'Malley: Yeah. Well, that's a deep question. I think that the most meaningful impact that you can have is the impression you leave on the people that you interacted with, right? And I think, for me, I would just hope that the people that I've had the chance to spend time with-- obviously family, friends, people I worked with, people who worked on my teams-- I would just hope that as they would reflect on the time that we had together, that it would be a memory that was time well spent and that hopefully there are some good shared experiences that we had and that hopefully I left something that was meaningful. But as it relates to the work that we're doing, I hope that the impact that we're having-- some of it has a longer reach than even what we can see today, 'cause I think, truly being selfless is trying to build things that you'll never realize the benefit of: planting trees that you'll never sit under yourself. It's for someone else down the line in the future. [00:23:14] Lindsey Dinneen: Yeah. Yeah. I love thinking about it in those terms too: being willing to do your bits of good and let them go out into the world and not necessarily know the ripple effects and still use that as a worthwhile use of your time. I love that. And then final question, what is one thing that makes you smile every time you see or think about it? [00:23:39] Tyler O'Malley: Yeah, I think the easy answer is probably my kids. So I have two kids, and that's kind of the reprieve from the work life and kind of focusing on all this important stuff that we're trying to do here at work, but being able to kind of break away from that and focus on building them up and watching them grow and develop and become their own person is really cool. It's obviously a unique experience and it's a nice thing to be able to think about when you need something to kind of bring you back up. [00:24:12] Lindsey Dinneen: Yeah, absolutely. Just a different way of looking at the world from such a fun perspective. I love that. [00:24:19] Tyler O'Malley: Yeah. [00:24:20] Lindsey Dinneen: Yeah. Well, Tyler, this has been such a great conversation. I so appreciate your time today telling us a little bit about your story, the company, and all the incredible work that you guys are doing to change lives for a better world. And we are so honored to be making a donation on your behalf as a thank you for your time today to Save the Children, which works to end the cycle of poverty by ensuring communities have the resources to provide children with a healthy, educational, and safe environment. So thank you so much for choosing that charity to support, and thank you so much for being here and thank you for doing what you do. [00:24:59] Tyler O'Malley: Thank you. It's it's been a pleasure. [00:25:01] Lindsey Dinneen: Excellent, and thank you also to our listeners for tuning in, and if you're feeling as inspired as I am, I'd love it if you'd share this episode with a colleague or two and we'll catch you next time. [00:25:14] Dan Purvis:  The Leading Difference is brought to you by Velentium Medical. Velentium Medical is a full service CDMO, serving medtech clients worldwide to securely design, manufacture, and test class two and class three medical devices. Velentium Medical's four units include research and development-- pairing electronic and mechanical design, embedded firmware, mobile app development, and cloud systems with the human factor studies and systems engineering necessary to streamline medical device regulatory approval; contract manufacturing-- building medical products at the prototype, clinical, and commercial levels in the US, as well as in low cost regions in 1345 certified and FDA registered Class VII clean rooms; cybersecurity-- generating the 12 cybersecurity design artifacts required for FDA submission; and automated test systems, assuring that every device produced is exactly the same as the device that was approved. Visit VelentiumMedical.com to explore how we can work together to change lives for a better world. 

Welcome back to another episode of the unSeminary podcast. Today we're joined by Eric Garza, Executive Pastor at Cross Church in Texas. Founded in 1995, Cross Church has grown into one of the fastest-growing churches in America, with 12 campuses across the Rio Grande Valley and beyond. With a unique focus on bilingual ministry, Cross […]

Investigative reporter and Kansas City native James Steele has worked in journalism for over six decades. He believes that the state of investigative journalism — led today by local and regional nonprofit outlets — is in better shape than most people might think.

On today's Legally Speaking Podcast, I'm delighted to be joined by Marcin Durlak.  Marcin is the Managing Partner and Co-Founder of IMD Solicitors LLP, an award-winning boutique firm recognised for its culture-first leadership and bold innovations. He and his wife and business partner,were jointly named Managing Partners of the Year at the 2025 ModernLaw Awards, after pioneering a 4-day working week with 100% pay whilst achieving record growth and world-class satisfaction. Passionate about culture-first leadership, Marcin is redefining what success looks like in the legal industry. From arriving in the UK with 1 suitcase to running an award-winning firm, his story is proof that bold ideas can transform both business and lives.So why should you be listening in? You can hear Rob and Marcin discussing:- Pioneering a Four-Day Work Week in Legal Practice- Building IMD Solicitors: From Language Skills to Award-Winning Firm- Overcoming Challenges and Embracing Continuous Improvement- Leveraging Technology and Innovation for Growth- Cultivating Culture, Team, and Balanced Firm ExpansionConnect with Marcin Durlak here - https://www.linkedin.com/in/marcin-durlak

AI Therapy: Can An Algorithm Help You More Than A Human? Will AI therapy promote even more isolation within society? Dr. Michael Heinz, a research psychiatrist, is part of a team using generative AI to act as a therapist for people with anxiety, depression, and eating disorders. Dr. Michael Heinz explains how this always-available AI therapist measures up to human-based therapy, and how AI best fits into the future of mental health.' Segment 2: CAR-T Cell Therapy: Pioneering The Future Of Cancer Treatment CAR T-cell therapy is a groundbreaking cancer treatment that reprograms a patient's own immune cells to recognize and destroy cancer. First approved by the FDA in 2017, it's already shown success in patients with blood cancers that no longer respond to standard treatments. While the therapy can cause serious side effects, our expert this week –a pioneer of this therapy– discusses the future of using this powerful new weapon against cancer. Learn more about your ad choices. Visit megaphone.fm/adchoices

CAR T-cell therapy is a groundbreaking cancer treatment that reprograms a patient's own immune cells to recognize and destroy cancer. First approved by the FDA in 2017, it's already shown success in patients with blood cancers that no longer respond to standard treatments. While the therapy can cause serious side effects, our expert this week –a pioneer of this therapy– discusses the future of using this powerful new weapon against cancer. Learn more about your ad choices. Visit megaphone.fm/adchoices

Ep. 77 - Many of you know Dallas PD's Joe King as the host of the compelling podcast “ATO: Bridging the Divide” which supports the mission of the Assist the Officer Foundation. Joe joined The Dallas Police Department in 1997, starting out in the Southeast Division. We talk about why he chose law enforcement, an early critical incident that sticks with him to this day, and how he quickly was drawn to street level narcotics and gangs which he worked for 20 years.On July 7th, 2016, everything changed for Joe, the Dallas Police Department and Dallas. That night, while DPD was working an anti-police protest, a shooter opened fire on officers working the protest, killing five, injuring nine other officers and two civilians. Those we lost are known as the Dallas Five, and they include one of Joe's close friends, Senior Corporal Lorne Ahrens. Joe recounts how the tragic events of that night unfolded with much of the killing horrifyingly playing out on live television. He details the SWAT response and the hours-long standoff that resulted in the shooter's being neutralized by a bomb on a remote-controlled bomb robot.The shooting was the deadliest incident for US law enforcement since 9/ 11, surpassing the March 2009 shootings of four officers in Oakland, CA, and the November 2009 murders of four officers just south of Seattle in Lakewood, WA known as the Lakewood Four. Their deaths were preceded by the ambush murder of Seattle Police Officer Timothy Brenton less than a month earlier. I lived in the greater Seattle area at the time and experienced the devastation of this tragedy. When the Dallas Five were killed, as I tell Joe, I may have been thousands of miles away, but my heart was with Dallas.Joe shares the impact on him and his fellow officers. His journey through grief and the cumulative effect of prior traumas led him to seek help through the Assist the Officer Foundation's confidential counseling.Joe has since joined the board of the Foundation which is a non-profit that not only provides trauma support but also financial assistance to first responders in need. Joe amplifies the mission with the “ATO: Bridging the Divide” podcast for which he interviews first responders from Dallas and around the country. They share their stories of trauma and resilience and how their agencies handle wellness.Joe also helped create and serves on Dallas PD's Wellness Unit which takes a very proactive role in caring for Dallas police officers. That Unit and ATO were both put to the test following the 2024 ambush murder of Officer Darron Burks who, only a few months out of the Academy, was shot and killed while in his patrol car. Joe says, “the Wellness Unit snapped into action that night. It was really a night-and-day response from 2016 to 2024 with critical incident response.”Thank you, Joe for all you have done and for all you do.I'd like to honor The Dallas Five for their service and for paying the ultimate sacrifice to protect the rest of us:Senior Corporal Lorne AhrensOfficer Patricio Enrique ZamarripaOfficer Michael Leslie KrolSgt. Michael Joseph SmithDART Officer Brent Thompson And to honor

Neal Shah's journey, showcases the impact of caregiving on individual lives and the broader healthcare system. Raised in a close-knit immigrant family, Neal's values were shaped early by the examples set by his parents and grandparents. After building an impressive career in finance, a series of personal experiences as a caregiver—first supporting his grandfather through end-of-life care, then facing his wife's severe illness—transformed his outlook and priorities. He became intimately aware of both the emotional toll and practical challenges caregivers face and the systemic flaws that make caregiving in America so difficult.These experiences motivated Neal to leave his high-powered finance career to focus on creating social impact. He founded Carry Ya, a not-for-profit project that connects families in need with qualified, motivated student caregivers at affordable rates, disrupting the expensive, often impersonal agency model. Neal is also the author of the book "Insured to Death," which exposes the failures of the American health insurance system, and he launched Counterforce Health, an AI-powered platform that empowers patients and caregivers to fight insurance denials. Neal's innovative, empathetic responses to systemic challenges underline his commitment to honoring caregivers as the backbone of the healthcare system and ensuring that their support, as well as that of care recipients, is financially and emotionally sustainable.About Neal:America's Chief Elder Officer. CEO of CareYaya Health Technologies and Chairman of Counterforce Health. Working hard to improve healthcare. Author of #1 Bestseller in Health Policy, "Insured to Death: How Health Insurance Screws Over Americans - And How We Take It Back". After a successful career as a $250 million hedge fund manager, deeply personal caregiving experiences inspired a pivot to social entrepreneurship. Now, determined to transform care delivery through technology.Building a rapidly-growing tech startup to expand access to affordable care. Pioneering cutting-edge AI applications and neurotechology to fundamentally elevate quality of life for those needing care. Motivated by creativity and humanitarian progress.Leveraging experiences guiding multi-billion dollar investments to make an impact on improving care for our most vulnerable populations. Leading with both heart and analytical rigor.Building unrivaled technical capabilities and strategic partnerships to establish CareYaya as America's leading launchpad for care innovation. Together, let's build a better future for care! Thank you to sponsor: CareScoutSupport the showConfessions of a Reluctant Caregiver Sisterhood of Care, LLC Website: www.confessionsofareluctantcaregiver.com Like us on Facebook! Tweet with us on Twitter! Follow us on Instagram! Watch us on Youtube! Pin us on Pinterest! Link us on LinkedIn!Tune in on Whole Care Network

Welcome back to the Alt Goes Mainstream podcast.Today's episode dives into the evolution of infrastructure investing with a leading scaled specialist firm in infrastructure.We sat down in Stonepeak's Hudson Yards office with a pioneer in infrastructure investing: Mike Dorrell.Mike is the Chairman, CEO, and Co-Founder of Stonepeak, building the foundations for the firm to achieve a rapid ascent to $76B from its founding in 2011.Mike brings deep expertise to bear in the infrastructure asset class. He has over 20 years of experience investing in infrastructure, starting his career at Macquarie, where he ultimately held the title of Senior Managing Director. He then joined Blackstone, where he was a Senior Managing Director in Private Equity and Co-Head of the Infrastructure Investment group, before striking out on his own to build one of the industry's largest infrastructure investing firms in Stonepeak.Mike and I had a fascinating and thought-provoking discussion about infrastructure investing and why it's becoming an increasingly important part of the private capital ecosystem. We covered:The early days of infrastructure investing.How infrastructure investing has evolved.How Mike's experiences at Macquarie and Blackstone informed how he wanted to build Stonepeak.How institutional investors have approached infrastructure investing and why individual investors should consider exposure to infrastructure assets.Stonepeak's DNA and what makes the firm different from other infrastructure investors.Why being a scaled specialist is a competitive advantage.How Stonepeak was built from scratch to scale.How Stonepeak identified investing in data centers early on and well before the data center boom began.Why launch a wealth solutions business and how it's a reflection of the firm's DNA, culture, and values.Thanks Mike for coming on the show to share your expertise, wisdom, and passion for infrastructure investing.A word from AGM podcast sponsor, Ultimus Fund SolutionsThis episode of Alt Goes Mainstream is brought to you by Ultimus Fund Solutions, a leading full-service fund administrator for asset managers in private and public markets. As private markets continue to move into the mainstream, the industry requires infrastructure solutions that help funds and investors keep pace. In an increasingly sophisticated financial marketplace, investment managers must navigate a growing array of challenges: elaborate fund structures, specialized strategies, evolving compliance requirements, a growing need for sophisticated reporting, and intensifying demands for transparency.To assist with these challenging opportunities, more and more fund sponsors and asset managers are turning to Ultimus, a leading service provider that blends high tech and high touch in unique and customized fund administration and middle office solutions for a diverse and growing universe of over 450 clients and 1,800 funds, representing $500 billion assets under administration, all handled by a team of over 1,000 professionals. Ultimus offers a wide range of capabilities across registered funds, private funds and public plans, as well as outsourced middle office services. Delivering operational excellence, Ultimus helps firms manage the ever-changing regulatory environment while meeting the needs of their institutional and retail investors. Ultimus provides comprehensive operational support and fund governance services to help managers successfully launch retail alternative products.Visit www.ultimusfundsolutions.com to learn more about Ultimus' technology enhanced services and solutions or contact Ultimus Executive Vice President of Business Development Gary Harris on email at gharris@ultimusfundsolutions.com.We thank Ultimus for their support of alts going mainstream.Show Notes00:00 Message from our Sponsor, Ultimus01:18 Welcome to the Alt Goes Mainstream Podcast02:10 Guest Introduction: Mike Dorrell03:58 Mike's Journey to Stonepeak06:46 Challenges in the US Infrastructure Market11:09 Successes and Setbacks in Infrastructure Deals12:06 Privately Held Infrastructure in the US17:05 Public vs. Private Infrastructure18:34 Impact of Infrastructure on Daily Life19:16 Stonepeak's Significant Market Presence22:10 Balancing Public Good and Investor Returns22:53 Regulation and Good Judgment in Infrastructure23:55 Challenges in Privatization25:52 Skills Needed for Infrastructure Investing26:29 Access to Infrastructure for Individual Investors27:10 Institutional Market's Experience with Infrastructure30:50 Asset Allocation and Infrastructure33:40 Private Equity vs. Infrastructure Investments34:10 Institutional Allocation Trends34:46 Patience and Peace of Mind in Investing35:14 Warren Buffet's Investment Philosophy35:38 Biggest Risks in Infrastructure35:50 Electric Utility Asset Risks36:28 Data Center Business Risks37:02 Evaluating Data Center Investments38:46 Economic Differences: Building vs. Buying Data Centers40:21 Pricing Power in Data Centers46:03 Connectivity Data Centers Explained49:16 Navigating Infrastructure as an Asset Class50:09 Finding the Right Assets at Fair Prices50:27 The Evolution of Infrastructure Investing53:31 Founding Stonepeak57:20 Raising Capital in Early Days59:46 Lessons from Blackstone01:01:22 Building a Strong Investment Culture01:03:37 Maintaining Culture While Scaling01:06:20 The Importance of the Wealth Channel01:07:41 Focus on Quality and Customer Experience01:08:33 Cycling and Business Philosophy01:09:26 The Importance of Investment Decisions01:10:27 Final Thoughts on Investment ProcessEditing and post-production work for this episode was provided by The Podcast Consultant.

Dr. Quintard Taylor was a legendary scholar of Black history in Seattle and the American West. He passed away last month at 76 years old. We’ll hear about him and his impact from a mentee and a friend. We can only make Seattle Now because listeners support us. Tap here to make a gift and keep Seattle Now in your feed. Got questions about local news or story ideas to share? We want to hear from you! Email us at seattlenow@kuow.org, leave us a voicemail at (206) 616-6746 or leave us feedback online.See omnystudio.com/listener for privacy information.

Solange Peters, MD, PhD - Pioneering Precision: A Real-World Roadmap to Optimal Outcomes in NTRK Fusion-Positive and HER2-Mutant Advanced NSCLC

Aisling Kenny reports on pioneering heart surgery being carried out on children with heart defects at CHI Crumlin.

Luigi Lenguito is the founder and CEO of BforeAI, which recently announced $15 million in Series A funding led by SYN Ventures. In this episode, he joins host Paul John Spaulding to discuss the announcement, including what the funding will be used for, and more. • For more on cybersecurity, visit us at https://cybersecurityventures.com

Viral vectors are the backbone of cutting-edge cell and gene therapies, delivering life-altering treatments to patients with genetic diseases. But making these biological delivery vehicles is a high-wire act: unpredictable, complex, and fraught with hurdles that traditional biologics manufacturers have never faced.While the world races toward next-generation therapies, the challenge of producing viral vectors at clinical and commercial scale threatens to leave patients waiting on the sidelines.Our guest on the Smart Biotech Scientist Podcast is Lucas Chan, a molecular and cell biologist with over two decades of hands-on experience in cell and gene therapy development. From his formative research at Imperial College London, where he pioneered novel viral vector cell lines, to building the UK's first GMP clinical viral vector core and later founding CellVec Pte Ltd Asia Pacific CDMO in Singapore, Lucas is the go-to architect for manufacturing viral vectors where infrastructure barely exists.Along the way, he's faced and overcome challenges few others could imagine.Here are three reasons this episode is a must-listen:Viral Vectors Demystified: Lucas breaks down a common misconception: viral vectors aren't malignant viruses, but genetically disarmed delivery vehicles that can't revert or replicate, making them safe tools for gene therapy.Manufacturing Mayhem Made Manageable: Unlike monoclonal antibodies and other biologics, viral vectors (and other cell and gene therapies) are made in living cells, leading to a level of process unpredictability and complexity where “everything, everywhere, all at once” applies. Success hinges on scientific acumen and attention to even the smallest detail, from raw materials to equipment parameters, to ensure patient safety and product quality.Pioneering in Uncharted Territory: Moving from London to Singapore, Lucas faced not just technical but regulatory and logistical challenges to founding Asia-Pacific's first CDMO dedicated to viral vectors. His advice: engage regulators early, leverage local biomanufacturing strengths, and build multidisciplinary teams to transfer and scale bioprocess know-how.Curious how viral vector manufacturing can be reimagined to unlock the full promise of cell and gene therapies? Listen to this episode and gain unique insights into the science, strategy, and sheer determination needed to bring advanced therapies out of the lab and into the clinic.Connect with Lucas Chan:LinkedIn: www.linkedin.com/in/lucaschangtNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? We're building a CMC Dashboard in Excel to help biotech founders track tasks, timelines, and risks in one place. Join the waitlist for early access at https://scale-your-impact.notion.site/27dd9c6ba679804b80a7ce439d56c91a?pvs=105

In this conversation, Makhosi Hefisah Nejeser discusses the emergence of a significant business revolution led by ultra-successful women entrepreneurs. She highlights the signs of awakening among these women, the urgency for systemic change due to the climate crisis, and the characteristics that define pioneering female leaders. The discussion emphasizes the need for a shift in wealth distribution and the importance of conscious capitalism. Makhosi outlines the phases of this revolution and calls on listeners to recognize their role in this transformative journey.TakeawaysWe are witnessing the beginning of the greatest business revolution.Ultra-successful women are being called to create a planetary legacy.Spiritual emptiness among successful women is an activation of a calling.Wealth accumulation is at historical highs, especially among women.The climate crisis creates an undeniable urgency for systemic change.Women are increasingly controlling consumer spending and investment decisions.The future of business must prioritize purpose over profit.Pioneering women possess unique characteristics that enable them to lead change.The revolution will unfold in phases, starting with awakening and leading to implementation.Your role in this transformation is crucial for collective impact.Support the show

After a spinal cord injury from a skiing accident left him paralyzed, Bob Meserve of Fort Collins didn't abandon the sport he'd fallen in love with as a young kid -- he instead chose to help transform it! The award-winning sit-skier turned adaptive sports industry leader, will be inducted into the Colorado Snowsport Museum Hall of Fame this weekend. We also remember a Vail icon, John Dakin, the longtime “face” of the U.S. Ski Team who became a pioneering ski race caller. Plus, this season is the last run for Powderhorn's West End ski lift built in 1972. 

In this episode of TechMagic, host Lee Kebler is joined by Nic Hill, co-founder and Chief Innovation Officer of Sawhorse Productions, to explore the latest tech developments shaping our digital world. Together, they break down Meta Connect's memorable moments and mobile-first pivot with Horizon Worlds, Intel's surprising $5B partnership with NVIDIA, and Lee's first-hand experience with Waymo's autonomous vehicles. The discussion also covers TikTok's potential acquisition by Oracle and the future of AR glasses and spatial computing. With insider insights and thoughtful analysis, Lee and Nic unpack how legacy tech companies are navigating rapid innovation, offering a must-listen guide for tech enthusiasts and professionals alike. Cathy is away this week and will rejoin the show next week.Come for the tech and stay for the magic!Lee Kebler Bio:Lee has been at the forefront of blending technology and entertainment since 2003, creating advanced studios for icons like Will.i.am and producing music for Britney Spears and Big & Rich. Pioneering in VR since 2016, he has managed enterprise data at Nike, led VR broadcasting for Intel at the Japan 2020 Olympics, and driven large-scale marketing campaigns for Walmart, Levi's, and Nasdaq. A TEDx speaker on enterprise VR, Lee is currently authoring a book on generative AI and delving into splinternet theory and data privacy as new tech laws unfold across the US.Lee Kebler on LinkedInNic Hill Bio:Nic Hill is the Co-Founder and Chief Innovation Officer at Sawhorse Productions, a full-service production and post house specialising in branded content, commercials, and scripted and non-scripted shows. With over 12 years of experience, Nic has assembled a talented team of experts in video production, editing, and comedy. Passionate about immersive metaverse experiences that blur the line between film and gaming, he delivers innovative content for leading brands, studios, and agencies worldwide. Previously, Nic worked as an independent film director and editor, creating internationally acclaimed documentaries. Based in Los Angeles, he enjoys DJing, biking, and family time.Nic Hill on LinkedInKey Discussion Topics:00:00 Intro & Welcome from LA05:31 Inside MetaConnect: A Front Row Perspective08:15 Meta's Smart Glasses Evolution & Design Strategy21:27 Horizon Worlds' Mobile-First Transformation33:35 First-Hand Experience with Waymo's Self-Driving Cars40:45 NVIDIA's $5B Investment in Intel: Gaming's Future44:30 Oracle's TikTok Acquisition & Social Media Shifts51:25 The Smart Glasses Arms Race: Amazon & OpenAI Enter55:31 Final Thoughts: Alien Earth & AI Evolution Hosted on Acast. See acast.com/privacy for more information.

Listen in as Paige and Cynthia talk with Caitlyn about breaking generational curses and walking in true freedom as a Christ follower from a young age. Caitlyn is an avid learner and has been hungry for God's Word most of her life.  To that precious Aunt that gave Caitlyn her first bible--look at the new legacy being created from that act of obedience and love.

Seed saving is one of the most valuable skills a gardener can learn, and in this episode I'm joined by Don Tipping of Siskiyou Seeds to dive deep into the why and how of saving your own garden seed. We'll cover the difference between open-pollinated, heirloom, and hybrid varieties, which crops are best for beginners, how to prevent cross-pollination, and tips for harvesting, drying, and storing seeds so they last for years.  Don also shares how seed saving helps you develop plants uniquely adapted to your microclimate, creating the heirlooms of tomorrow. Whether you're brand new to seed saving or looking to refine your skills, this conversation will inspire and equip you to grow a more resilient, self-sufficient garden. For more information and any links mentioned in today's podcast, visit https://melissaknorris.com/481 This podcast is sponsored by Redmond Real Salt. Did you know Redmond sells much more than just salt? I love their bentonite clay powder and it's a must-have in our house because we use it for wound care. Check out all of Redmond's products at melissaknorris.com/redmond-salt and use code "PIONEERING" at checkout for 15% off your order.