Podcasts about stem cell transplant

When Phil Mamwell first felt sharp, shooting pains, he did what too many men do — he told himself he'd be all right and hoped it would pass. By the time the excavator driver from rural Lincolnshire, England, was diagnosed with testicular cancer in his late 30s, it had already metastasized. In this raw and honest episode of It Takes Balls, Phil shares two years of hell — and the hard-won perspective that came with surviving against the odds.Phil's story is a powerful reminder of why early detection matters. Testicular cancer had never been on his radar, and he's candid that had he been seen sooner, he might have needed nothing more than an orchiectomy. He could feel the BEP working almost immediately as his tumor shrank — only for the cancer to return six weeks later, right around Christmas. From there, Phil faced relapse after relapse. His orchiectomy came after his first chemo, with tumor markers still rising. Second-line VIP chemotherapy followed, along with a stem cell harvest he was certain he'd never need. When the disease came back yet again, he was given a roughly 20% chance of survival and chose high-dose ToPCaT chemotherapy, followed by a stem cell transplant and, finally, an RPLND to remove the residual tumors. The pathology came back with no evidence of disease.Phil doesn't sugarcoat survivorship. He lives with chemo brain, ringing in his ears, and neuropathy, and his hair never fully grew back. He speaks movingly about the survivor's guilt he carries after losing a fellow patient from his own town — a young man with the same embryonal carcinoma diagnosis whom he'd befriended and encouraged. And he's honest about how disorienting remission can be, describing himself as "a dog on a lead" suddenly let loose, not quite trusting it's over until he reaches the ten-year mark at 50.Through it all, Phil credits his wife — who graduated as a nurse mid-treatment — along with his kids, parents, friends, and employer for carrying him through. His advice to men in their late 30s and beyond is simple and urgent: don't make the mistake he did. Check yourself, see a doctor, and don't leave it. Look after your balls.Provide your feedback on the podcast:https://www.testicularcancerawarenessfoundation.org/itbsurveyJoin The Ball Room:https://www.testicularcancerawarenessfoundation.org/theballroomWant to be a guest? Apply here:https://www.testicularcancerawarenessfoundation.org/it-takes-balls-submissionsConnect with Phil:https://www.facebook.com/philmamwellFollow Testicular Cancer Awareness Foundation:⁠https://www.testescancer.orghttps://www.x.com/testescancer⁠https://www.instagram.com/testescancerhttps://www.facebook.com/tca.orgFollow Steven Crocker:https://www.instagram.com/stevencrockerhttps://www.facebook.com/steven.crocker2Theme song: No Time Like Now - Tom Willner www.tomwillner.com

We meet Mitch McPherson, a Georgia law enforcement officer who was diagnosed with high risk myelofibrosis in February 2025. His symptoms began months earlier with fatigue, weakness, shortness of breath, and facial tingling. Mitch learned that a stem cell transplant offered his best path forward, but his doctors worried that finding a young, fully matched donor could be difficult. Within days, Mitch received unexpected news. Multiple donors were perfect 10 out of 10 matches. The first donor could not meet the required schedule, but a second donor, a 26 year-old woman from the United States, agreed to proceed. Mitch also received support from DKMS and members of his sheriff's department, who organized a donor registration drive. Before the transplant, Mitch took Vonjo to reduce the risk of his disease progressing to leukemia. He then completed five days of intensive chemotherapy and received his stem cell transplant on June 11, 2025. Due to his fitness. he tolerated intense chemotherapy better than he expected, but the effects became more difficult during the following weeks. At one point, he took about 27 pills twice a day. Mitch later developed Graft Versus Host Disease, or GvHD. It caused mouth pain, dry eyes, itching, fatigue, weakness, altered taste, and difficulty eating. Foods with vinegar burned his mouth, while soft foods, dairy, fruit, baked potatoes, and bean burritos were easier to tolerate. The illness also reduced his strength so severely that he had to begin rebuilding muscle with five pound dumbbells. His recovery became harder because he returned to work far earlier than his doctors recommended. He later developed pneumonia and a blood clot in his lung. His doctors then removed him from work for six months. Mitch says the experience changed his outlook and revealed which relationships were dependable. Faith remained central throughout his journey. Interestingly, a year before his diagnosis, Mitch dreamed that Jesus told him he would become sick, but would be okay. That message gave him confidence during his diagnosis, donor search, transplant, and complications. Mitch's strongest advice is simple. We should not try to prove our toughness by ignoring medical guidance. When doctors tell us to rest and allow the body to heal, we need to listen. Mitch now focuses on recovery while finding new outlets through fishing, a possible YouTube channel, and songwriting. Thank you to our Season 21 Sponsors: Incyte: https://incyte.com/ Sanofi: https://www.sanofi.com/ (00:00) Intro (01:33) Symptoms and Myelofibrosis Diagnosis (03:51) Multiple Perfect Donor Matches (05:46) Medication, Chemotherapy, and Transplant Preparation (08:43) Living With GvHD (11:27) Support, Isolation, and Changing Relationships (13:44) The Dream That Gave Mitch Hope (16:52) Returning to Law Enforcement After Transplant (20:22) Recovery, Mental Health, and Ongoing Treatment (23:17) Mitch's Advice for Transplant Patients National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/Check out our valued nbmtLINK resource books, some for sale, some free as downloadable, https://www.nbmtlink.org/shop/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.This content is provided for informational purposes only and is not intended to substitute for professional medical advice, diagnosis, or treatment. It is crucial to consult directly with a qualified healthcare professional regarding any medical conditions, treatment options, or other health concerns.The views and opinions expressed by the speakers are their own and do not necessarily reflect the official policy or position of the nbmtLINK. Unless otherwise stated in an official policy, the nbmtLINK does not endorse any specific treatments, products, or services mentioned by the speakers. Reliance on any information provided is solely at your own risk.The Marrow Masters Podcast is produced by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode, we hear from Joanne Claxton, wife and caregiver to acute myeloid leukemia (AML) survivor Adam Claxton. Adam was a guest in Season 20 and you can listen to his episode here. Joanne takes us back to Adam's diagnosis in 2024. He had a persistent cough and had visited his general practitioner several times. After being sent home with antibiotics, he went to the hospital's accident and emergency department. He was initially discharged but was soon called back and told to pack a bag. After an anxious wait, two hematology consultants told Joanne and Adam that he had AML. The news shocked their entire family. While Adam underwent chemotherapy, Joanne had to protect a sense of normality for their three children. She stopped working and took on the responsibilities of solo parenting while Adam remained in the hospital. When Adam relapsed in 2025, Joanne found the experience even more difficult than the original diagnosis. He had completed chemotherapy and a transplant and appeared to be recovering well. He had even been exercising the day before the relapse was discovered. Because he was home rather than hospitalized, the family lived with greater uncertainty. Joanne says this was the point when she hit rock bottom. After transplant, Adam developed chronic Graft-Versus-Host Disease, or GVHD, affecting his skin. But Joanne and Adam view it as the price of continued protection against leukemia. This perspective does not remove the difficulty, but it helps them face the condition with hope. Their cancer experience also brought them closer. They had not planned to marry before Adam became ill, but his diagnosis changed their priorities. They married during the journey and developed a deeper understanding of one another. Joanne is honest about the delayed effects of caregiving. She experienced anxiety, vertigo, headaches, neck pain, and other physical signs of stress. She eventually reached out for help and learned that caring for herself was necessary. She no longer allows guilt to prevent her from taking time for herself. Peg asks Joanne what the hardest moment was - and her answer is striking. Joanne's main advice to caregivers is to surround themselves with supportive people, talk openly, accept help, and use available charities and caregiver networks. No matter how strong someone may be, caregiving should not be carried alone. Joanne also reminds friends and family to ask how the caregiver is doing. Ordinary conversations can provide relief when illness has consumed every part of life. Above all, Joanne and Adam live one day at a time and choose faith over fear. Thank you to our Season 21 Sponsors: Incyte: https://incyte.com/ Sanofi: https://www.sanofi.com/ (00:00) Intro (01:14) Adam's acute myeloid leukemia diagnosis (03:24) Watching a partner go through treatment (05:18) Why the relapse felt even harder (08:13) Understanding graft versus host disease (09:50) How cancer changed their relationship (12:56) Advice for partners and caregivers (15:39) The helplessness caregivers experience (17:34) Releasing caregiver guilt (18:00) Difficult conversations about wills and funerals (20:08) Faith over fear after a GVHD diagnosis (23:09) The importance of ordinary conversations National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/Check out our valued nbmtLINK resource books, some for sale, some free as downloadable, https://www.nbmtlink.org/shop/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.This content is provided for informational purposes only and is not intended to substitute for professional medical advice, diagnosis, or treatment. It is crucial to consult directly with a qualified healthcare professional regarding any medical conditions, treatment options, or other health concerns.The views and opinions expressed by the speakers are their own and do not necessarily reflect the official policy or position of the nbmtLINK. Unless otherwise stated in an official policy, the nbmtLINK does not endorse any specific treatments, products, or services mentioned by the speakers. Reliance on any information provided is solely at your own risk.The Marrow Masters Podcast is produced by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

We speak with Dr. Ryan Lee of Memorial Sloan-Kettering Cancer Center about dental care before, during, and after a bone marrow or stem cell transplant. Dr. Lee is a chief dental officer, lieutenant colonel, oral oncologist, and implantologist. He explains why dental planning must consider more than the immediate transplant period. As treatments improve, many survivors are living for decades. Their teeth and gums need to support them throughout long term survivorship. Patients undergoing transplant may face weakened immunity, infection, bleeding, mouth sores, dry mouth, pain, taste changes, and difficulty chewing or swallowing. These problems can occur together and make each other worse. A mild dental issue can become a serious infection when blood counts are low. Poor oral health can also interfere with eating and maintaining proper nutrition. Dental clearance should identify teeth that must be treated before transplant and problems that can safely wait. Dr. Lee stresses that this decision is different for every patient. Dentists need to understand the type of transplant, the likelihood of Graft Versus Host Disease, current medications, and the expected long term condition of each tooth. Communication between the dental team and the hematology and oncology team is essential. A strong daily oral care routine should begin before treatment. Patients should use a medium or soft toothbrush, clean between the teeth, and consider a water flosser when regular flossing causes bleeding. Dentures, partials, crowns, bridges, and implants require careful cleaning because they can collect bacteria and fungus. Patients should also know where these restorations are located so future dental providers can give specific instructions. Saliva acidity and dry mouth should also be discussed because they can greatly increase cavity risk. During treatment, mucositis may cause painful sores throughout the mouth. Frequent water intake, nutritional drinks, and prescribed mouth rinses may make eating more manageable. Some rinses contain antimicrobial medication and lidocaine to reduce infection risk and temporarily numb the mouth. Dental procedures must be planned around blood counts and medication schedules. Invasive work may be safest shortly before the next chemotherapy or immunosuppressive treatment, when blood counts have had the most time to recover. During neutropenia, elective treatment may need to stop while the dentist focuses on controlling pain and infection. During thrombocytopenia, extractions or other procedures may need to wait because bleeding may be difficult to control. Dr. Lee recommends creating a dental timeline that separates urgent pretransplant treatment from work that can wait six, twelve, eighteen, or twenty four months. Long term survivors should build a consistent relationship with dentists and hygienists who understand their medical history. Pediatric survivors require additional support because treatment can affect developing adult teeth, tooth roots, spacing, appearance, and self confidence. The central message is that dental care is part of transplant care. Early planning, daily prevention, current blood count information, and communication between providers can protect comfort, nutrition, and quality of life for many years. Thank you to our Season 21 Sponsors: Incyte: https://incyte.com/ Sanofi: https://www.sanofi.com/ (00:00) Introduction (01:12) Why dental care matters before transplant (02:23) Common oral complications (04:12) Which dental problems need treatment first (05:38) Transplant type and graft versus host disease risk (06:45) Protecting teeth for long term survivorship (10:39) Cleaning dentures, crowns, bridges, and implants (11:51) Saliva acidity and cavity risk (12:47) Mouth sores, bleeding, and trouble eating (13:57) Managing pain and maintaining nutrition (15:28) Dental care with low blood counts (17:29) Managing dentistry during neutropenia and thrombocytopenia (23:00) Long term dental survivorship (24:48) The role of dentists and hygienists (25:46) Oral graft versus host disease and limited mouth opening (27:34) Dental health decades after transplant (28:03) Dental development in pediatric survivors National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/Check out our valued nbmtLINK resource books, some for sale, some free as downloadable, https://www.nbmtlink.org/shop/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.This content is provided for informational purposes only and is not intended to substitute for professional medical advice, diagnosis, or treatment. It is crucial to consult directly with a qualified healthcare professional regarding any medical conditions, treatment options, or other health concerns.The views and opinions expressed by the speakers are their own and do not necessarily reflect the official policy or position of the nbmtLINK. Unless otherwise stated in an official policy, the nbmtLINK does not endorse any specific treatments, products, or services mentioned by the speakers. Reliance on any information provided is solely at your own risk.The Marrow Masters Podcast is produced by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Today hear from Julia Oppman, a two time acute myeloid leukemia survivor (AML)and patient advocate from Northeast Ohio. Julia shares how her cancer journey began in 2018 when she was 36 years-old and raising two young children. She initially blamed her extreme exhaustion on motherhood and work. After months of illness and repeated infections, she was diagnosed with AML. The diagnosis came unexpectedly by phone and was followed almost immediately by a 30 day hospital stay for induction chemotherapy. Julia later underwent minimal residual disease (MRD) testing. Eventually, the numbers increased and she relapsed in 2020. She was told that a bone marrow transplant was now necessary to save her life. The transplant took place during the COVID pandemic, creating additional challenges for Julia and her family. Hospital visitor restrictions led them to relocate so she could receive treatment at a hospital that allowed support people. Her husband, mother, and children became an essential part of her care during the transplant and the critical first 100 days afterward. Following transplant, Julia developed chronic Graft Versus Host Disease. She describes it as one of the most challenging parts of her experience because it can affect multiple areas of the body at different times. Her symptoms have required visits with many specialists, and she has struggled to find treatments that work for her. Insurance denials have created another barrier, especially when doctors want to consider medications that are not specifically labeled for Graft Versus Host Disease. Julia has become a strong advocate for herself and others. She sought evaluation at the National Institutes of Health (NIH) and plans to pursue additional expertise at Memorial Sloan Kettering Cancer Center in New York. She encourages patients to look for support groups, connect with others who have similar experiences, and continue searching for medical resources when existing options are not enough. One of Julia's biggest sources of purpose is her 'Share the Love' initiative. What began as Valentine's Day gifts for patients on her hospital floor has grown into an annual effort serving several hospitals, including a children's hospital. Her children now help create handmade Valentines for the packages. Julia also shares the unexpected birth of her youngest child after being told she would not be able to have more children. Through cancer, transplant, chronic GVHD, advocacy, motherhood, and giving back, she continues looking for what she calls the silver lining. Her message is clear. Life after transplant is not always simple or easy. Support often means showing up, listening, helping with every day tasks, and allowing patients to be honest about what they are experiencing. If you want to help Julia's Share The Love initiative, you can reach her at: jewelsjean@hotmail.com Thank you to our Season 21 Sponsors: Incyte: https://incyte.com/ Sanofi: https://www.sanofi.com/ Additional Resources: National Institutes of Health (NIH): https://www.nih.gov/ GVHD Alliance: https://www.gvhdalliance.org/ NeedyMeds: https://www.needymeds.org (00:00) Introduction (01:03) How Julia's cancer journey began (06:04) Relapsing during the COVID pandemic (07:18) Facing a bone marrow transplant in 2020 (08:09) Relocating the family and finding caregiver support (11:03) Creating the Share the Love Valentine's initiative (13:31) Living with chronic graft versus host disease (15:51) Resources for medication assistance (16:08) Seeking answers at NIH and Memorial Sloan Kettering (19:58) Support groups and learning from other patients (21:14) An unexpected pregnancy after transplant (23:31) Insurance barriers and financial toxicity (24:37) Putting the broken pieces of life back together (27:05) How friends can truly support patients National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/Check out our valued nbmtLINK resource books, some for sale, some free as downloadable, https://www.nbmtlink.org/shop/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.This content is provided for informational purposes only and is not intended to substitute for professional medical advice, diagnosis, or treatment. It is crucial to consult directly with a qualified healthcare professional regarding any medical conditions, treatment options, or other health concerns.The views and opinions expressed by the speakers are their own and do not necessarily reflect the official policy or position of the nbmtLINK. Unless otherwise stated in an official policy, the nbmtLINK does not endorse any specific treatments, products, or services mentioned by the speakers. Reliance on any information provided is solely at your own risk.The Marrow Masters Podcast is produced by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

We talk with Dr. Yazan Migdady about chronic Graft Versus Host Disease, post transplant cytopenias, and what patients and caregivers should understand about recovery after a blood or marrow transplant. Chronic GVHD develops when the donated immune system begins reacting against the patient's own cells. Dr. Migdady explains that it occurs in roughly half of transplant patients, although severe cases are much less common. When GVHD affects the bone marrow, it can interfere with the body's ability to produce healthy red blood cells, white blood cells, and platelets. Low blood counts after transplant can have several causes. GVHD itself may interfere with blood production or cause the immune system to attack blood cells. Medications used to control GVHD can also lower blood counts. Infections, poor graft function, and other transplant related complications can contribute as well. This is why regular monitoring and a thorough evaluation are so important. Dr. Migdady also explains when transfusions may be needed. Decisions are based not only on laboratory numbers but also on symptoms, bleeding risk, medications, and the patient's overall condition. Transfusions provide temporary support while the body is unable to produce enough blood cells on its own. Treatment options continue to improve. In recent years, several therapies for chronic GVHD have become available, giving clinicians more ways to individualize care. Clinical trials remain an important part of that progress and can sometimes give patients access to promising treatments years before they become widely available. Researchers are also investigating more targeted approaches for immune mediated cytopenias. The goal is to target the specific immune cells or pathways responsible rather than broadly suppressing the immune system. We also address the common idea that chronic GVHD eventually "burns out." For many patients, symptoms do improve as the immune system gradually settles down, and some can eventually stop treatment. However, this process varies considerably. GVHD can last months or years and can flare again, so patients need continued monitoring. Finally, we focus on the emotional side of recovery. Isolation is intended to protect patients while their immune systems are vulnerable, but staying connected with family and friends remains important. Caregivers should prepare for a marathon rather than a sprint, build their own support network, and take care of their own physical and emotional needs. Dr. Migdady closes by sharing several memorable patient stories that remind us that advances in transplantation are ultimately about the people behind the science. Thank you to our Season 21 Sponsors: Incyte: https://incyte.com/ Sanofi: https://www.sanofi.com/ (00:00) Intro (01:52) What Is Chronic Graft Versus Host Disease? (03:53) Can a Little GvHD Be Beneficial? (05:25) Why Blood Counts Can Stay Low After Transplant (07:50) Finding the Right GvHD Treatment (08:43) Why Clinical Trials Matter (09:58) When Are Blood Transfusions Needed? (11:58) New Therapies for Post Transplant Cytopenias (14:20) Does Chronic GvHD Eventually Burn Out? (15:56) Coping With Isolation During GvHD (17:36) Advice for Caregivers (19:43) Patient Stories That Made a Lasting Impact (22:36) Closing Thoughts National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/Check out our valued nbmtLINK resource books, some for sale, some free as downloadable, https://www.nbmtlink.org/shop/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.This content is provided for informational purposes only and is not intended to substitute for professional medical advice, diagnosis, or treatment. It is crucial to consult directly with a qualified healthcare professional regarding any medical conditions, treatment options, or other health concerns.The views and opinions expressed by the speakers are their own and do not necessarily reflect the official policy or position of the nbmtLINK. Unless otherwise stated in an official policy, the nbmtLINK does not endorse any specific treatments, products, or services mentioned by the speakers. Reliance on any information provided is solely at your own risk.The Marrow Masters Podcast is produced by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Survivor: Africa winner Ethan Zohn joins Rev. Dr. Robin Swan for a powerful conversation about cancer, cannabis, resilience and finding purpose after a life-changing diagnosis. Ethan's life had already taken him from professional soccer to winning CBS's Survivor: Africa when, at age 35, he was diagnosed with a rare form of Hodgkin lymphoma. What followed was an intense medical journey involving chemotherapy, radiation, clinical trials and two stem cell transplants. In this episode, Ethan shares his personal experience with medical cannabis and how it became part of the way he managed some of the physical and emotional challenges surrounding cancer treatment and recovery, including nausea, pain, sleep difficulties and anxiety. Ethan and Robin also discuss the changing conversation around cannabis in professional sports, the importance of responsible education and advocacy, and why patients need honest information when making decisions about their health. The conversation goes far beyond cancer. Ethan explains how surviving a life-threatening illness reshaped his sense of purpose and strengthened his commitment to helping others. He discusses Grassroot Soccer, the nonprofit organization he co-founded that uses the power of soccer to improve the health and lives of young people around the world, as well as Kicking Back, his High Times series exploring the intersection of soccer, cannabis and community. In this episode: Ethan's journey from professional soccer to winning Survivor: Africa Being diagnosed with Hodgkin lymphoma at age 35 Chemotherapy, radiation, clinical trials and two stem cell transplants Ethan's personal experience using cannabis during cancer treatment and recovery Cannabis for nausea, pain, sleep and anxiety The emotional and psychological challenges of cancer survivorship How attitudes toward cannabis are changing in professional sports Cannabis education, responsible use and patient advocacy Turning personal crisis into purpose The story and mission behind Grassroot Soccer Ethan's Kicking Back series with High Times Soccer, cannabis and community Using lived experience to help others facing serious illness Learn more about Ethan Zohn Ethan Zohn:https://ethanzohn.com Grassroot Soccer:https://grassrootsoccer.org Cannabis Health Radio Visit:https://cannabishealthradio.com If this conversation could help someone you know, please share the episode. Subscribe to Cannabis Health Radio for more conversations with patients, advocates, researchers and others exploring cannabis, health and healing. Connect with Cannabis Health RadioVisit us at CannabisHealthRadio.comExplore products and resources from Swan ApothecaryFollow Cannabis Health Radio on Facebook and InstagramImportant DisclaimerThe views and opinions expressed by guests on Cannabis Health Radio (CHR) are their own and do not necessarily reflect those of CHR, its hosts, producers, affiliates, or sponsors. CHR is not responsible for statements or opinions expressed by its guests.Nothing presented in this episode constitutes medical advice, diagnosis, treatment, or a recommendation regarding what you should do. This content is provided for informational and entertainment purposes only. Always consult a qualified healthcare professional regarding your health, medical conditions, medications, or treatment decisions. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode, Jodi Skiles, MD, Medical Director of the Pediatric Stem Cell Transplant Program at Riley Hospital for Children in Indianapolis, joins the podcast to discuss a groundbreaking milestone in pediatric medicine—the world's first bone marrow stem cell transplant using cells from a deceased donor in a 14-year-old patient. She shares the significance of expanding access to this innovative donor source and how advances in transplant medicine are creating new opportunities to improve outcomes for children in need of life-saving care.

It's Thursday, July 9. Here are today's top stories around Central Indiana. Want to go deeper on the stories you hear on WFYI News Now? Visit wfyi.org and follow us on social media to get local news every day. WFYI News Now is hosted by Barb Anguiano and produced by Zach Bundy. Subscribe wherever you get your podcasts.

Send us Fan MailAn MRI, a phone call, and four words nobody wants to hear: “You have a perforated bowel.” Zach Koscuik was on the road to a comedy gig when Crohn's disease forced yet another hard pivot, adding to a 25-year history that includes perianal Crohn's, fistulas, abscesses, emergency surgeries, biologics, and three ileocolonic resections. We talk with him about what it's like to grow up sick, manage the stigma that makes people minimize inflammatory bowel disease, and keep showing up to school, work, and life when your body is always negotiating the nearest bathroom.Then the story takes a turn into the world of clinical trials and high-stakes medicine. Zach explains how severe disease and short bowel complications pushed his team toward an autologous stem cell transplant, a process that essentially wipes out and restarts the immune system. We get specific about the testing, chemo, isolation, and the surreal experience of being treated on a cancer floor without having cancer, plus the very real impact of insurance decisions that kept him hospitalized for 43 days.The payoff lands with the kind of news IBD patients barely let themselves hope for: a one-year follow-up colonoscopy that comes back completely clean. We also keep it honest about what remains, including motility issues, joint pain, and the mental aftershocks of medical trauma. Zach closes with a simple challenge for the Crohn's and colitis community: practice equal empathy, because two people can share a diagnosis and live totally different realities. If this conversation hits home, subscribe, share the episode with a friend, and leave a review so more people living with IBD can find it.Links: Find Zach on InstagramInformation on the stem cell trial that Zach didStem Cell Therapy clinical trial site- Clinicaltrials.govLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

Dr. Mitch Shulman can be heard every weekday morning at 7:50 on The Andrew Carter Morning Show.

The primary season for Louisiana's U.S. Senate race is finally behind us, and we know who the Republican and Democratic candidates in the fall election will be. The Times-Picayune/New Orleans Advocate's editorial director and columnist Stephanie Grace tells us how Republican Julia Letlow and Democrat Jamie Davis made it this far. The Southern Poverty Law Center released its annual Year in Hate and Extremism report in early June, counting more than 1200 hate and extremist antigovernment groups across the country — and 33 across Louisiana, Mississippi, and Alabama. The report says the hard right is no longer knocking on the door of American institutions. It has walked through.Gulf States Newsroom intern Tanner O'Neal Riley has been covering the report and joins us with more. 23 year-old Daniel Cressy recently became the first patient in Louisiana to undergo gene therapy for sickle cell disease. Now that he's been functionally cured of the disease he can pursue his lifelong dream of becoming a pilot. He also co-founded Privileged Pilots, a nonprofit that encourages others going through medical challenges to still pursue their dreams. Dr. Ben Watkins, director of the Stem Cell Transplant and Cell Therapy Program at Children's Hospital New Orleans, tells us more.—Today's episode of Louisiana Considered was hosted by Karen Henderson. Our managing producer is Alana Schreiber. We receive production and technical support from Garrett Pittman, Adam Vos and our assistant producer, Aubry Procell. You can listen to Louisiana Considered Monday through Friday at noon and 7 p.m. It's available on Spotify, the NPR App and wherever you get your podcasts. Louisiana Considered wants to hear from you! Please fill out our pitch line to let us know what kinds of story ideas you have for our show. And while you're at it, fill out our listener survey! We want to keep bringing you the kinds of conversations you'd like to listen to.Louisiana Considered is made possible with support from our listeners. Thank you!

As Christians, we need to stay informed about the rapidly changing world of fertility treatments, genetic testing, and IVF before making decisions or forming opinions. Join C.L. as we explore the powerful story behind the Boozer family, wrestle with difficult questions about life, embryos, technology, and God's will, and seek biblical wisdom for navigating one of the most important ethical conversations of our time.

In this episode, we talk with Christy Donovan, DNP, RN, a Blood Cancer Coordinator at the the Blood and Marrow Transplant/ Leukemia Program at Northside Hospital Cancer Institute, about what survivorship really looks like after a stem cell transplant. The central message is that survivorship is not a finish line. It is a transition into a new normal. Many patients expect life to return to the way it was before diagnosis or transplant, but recovery usually feels slower, messier, and more emotional than that. Fatigue, side effects, fear, and frustration can last for months, and that does not mean something is wrong. It means recovery is still happening. We also focus on how important it is to set realistic expectations. Christy explains that early struggles do not define long term outcomes. A setback in the first weeks or months after transplant does not mean a patient will not go on to live a full and meaningful life. Recovery takes patience. Small wins matter. Walking to the mailbox, cooking a meal, or getting through a day with a little more energy can be major milestones. Over time, those moments add up. Another major theme is emotional recovery. We talk about the fear of recurrence and the challenge of learning what is normal after treatment versus what should be reported to a doctor. That education helps people feel more confident and less trapped by fear. We also touch on how easy it is to forget that some aches and pains may simply come with getting older, not always with cancer. That perspective can be grounding. Other survivors can be a valuable information resource, too. Support comes up again and again throughout the conversation. Caregivers remain important in survivorship, but their role changes. Friends, peer support, support groups, podcasts, and survivorship communities all help patients feel less isolated. Christy emphasizes the value of honesty and vulnerability, especially in telling people what kind of support is needed on a given day. Some days call for celebration. Some days call for rest. We also talk about the tension between wanting to get back to life and needing to stay safe. Many survivors ask when they can return to work, travel, attend church, or see family. That desire is a good sign. It shows hope. At the same time, it takes guidance from the healthcare team to know when and how to widen that protective bubble. The episode ends on a hopeful note. Christy shares that she does not think of one survivor story. She thinks of many faces. She describes the joy of seeing patients return months later looking stronger, brighter, and more like themselves. That image captures the heart of the episode. Survivorship is hard, but it is also full of possibility, growth, connection, and life after transplant. More: Northside Hospital Cancer Institute Blood & Marrow Transplant Program — https://www.northside.com/services/cancer-institute/cancer-treatment-options/blood-marrow-transplant-program Northside Hospital Cancer Institute Blood Cancer Program — https://www.northside.com/services/cancer-institute/cancer-programs/blood-cancer-program National Bone Marrow Transplant Link (nbmtLINK) — https://www.nbmtlink.org/ Thanks to this season's sponsors, Incyte and Sanofi. (00:00) Introduction (00:40) Meet Christy Donovan (01:42) Survivorship as a transition (03:00) The role of caregivers and support after transplant (03:38) Early struggles vs long term outcomes (05:41) Emotional impact and fear of recurrence (07:02) Learning what is normal and what is not (07:55) Support groups, healing arts, and community (08:44) Being honest with friends about what you need (09:34) Managing energy and celebrating small wins (11:02) Patience, hope, and finding your people (13:15) Common questions in early survivorship (14:27) Expanding the protective bubble (15:20) The many faces of survivorship (17:03) Final encouragement and close National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/Check out our valued nbmtLINK resource books, some for sale, some free as downloadable, https://www.nbmtlink.org/shop/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.This content is provided for informational purposes only and is not intended to substitute for professional medical advice, diagnosis, or treatment. It is crucial to consult directly with a qualified healthcare professional regarding any medical conditions, treatment options, or other health concerns.The views and opinions expressed by the speakers are their own and do not necessarily reflect the official policy or position of the nbmtLINK. Unless otherwise stated in an official policy, the nbmtLINK does not endorse any specific treatments, products, or services mentioned by the speakers. Reliance on any information provided is solely at your own risk.The Marrow Masters Podcast is produced by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Today, Peggy talks with Daniel Gaylor, LCSW, OSW-C, ACHP-SW, and a social work supervisor at Moffitt Cancer Center, about what happens after patients and caregivers get through the intense treatment period and begin asking, “Now what?” Daniel explains that recovery does not mean life snaps back to normal. Survivorship brings fear, relief, hope, uncertainty, and exhaustion all at once. Those reactions are normal, and they deserve to be named. Daniel explains why post-traumatic stress disorder (PTSD) can show up after transplant. A transplant is not a routine treatment. It can involve long hospital stays, isolation, major physical side effects, and real fears about survival. When patients return for follow up visits, they may be brought back emotionally to those difficult hospital days. This can make survivorship feel complicated, even when the transplant was successful. Another key theme is slowly letting go. Patients may feel afraid to go out, socialize, eat in a restaurant, drive, or return to activities they once enjoyed. Daniel encourages survivors to start small and to be fair to the situation. It is easy to imagine the worst case. But it also helps to keep yourself honest - say out loud what could happen if things go well. The episode also addresses the “strain of worry.” Daniel describes signs of anxiety and depression, including sleep problems, racing thoughts, trouble concentrating, irritability, sadness, appetite changes, and not wanting to do things that usually bring joy. He reminds listeners that difficult days do not mean failure. Survivors should be able to say, “Today is not my best day,” and ask for help. Peggy and Daniel also talk about toxic positivity. While loved ones often mean well, phrases like “you're lucky to be alive” can minimize a survivor's fear or pain. Daniel encourages honest communication. Patients can thank loved ones for their support while also explaining what would help more. Social connection is another major part of healing. Daniel urges survivors and caregivers to increase connection and reduce isolation. A quick text, a short call, a support group, or a shared conversation can make a real difference. Peggy highlights programs where survivors can meet others who understand graft versus host disease (GVHD) and transplant recovery. Daniel closes with the idea of building a “tool belt.” Each person needs practical coping tools, whether that is a friend, music, journaling, counseling, mindfulness, a book, or a favorite place to reset. Caregivers need their own tool belts too. Transplant affects the whole support system, and survivorship works best when people communicate, ask for help, and remember they are not meant to do this alone. Links: Elephants and Tea: https://elephantsandtea.org/ BMT InfoNet: https://bmtinfonet.org/ Blood Cancer United: https://bloodcancerunited.org/ Thanks to this season's sponsors, Incyte and Sanofi. (00:00) Intro (01:01) Normalizing emotional reactions during recovery (04:22) PTSD after transplant and why it matters (08:59) Slowly letting go after transplant (13:12) Facing the worst case and choosing to move forward (13:53) The strain of worry and mental health red flags (19:31) Toxic positivity and the power of validation (20:26) How to talk with loved ones who are trying to help (22:39) Social health, connection, and friendship (26:43) Support groups, GVHD, and feeling understood (28:07) Building a survivorship "tool belt" (33:08) Why transplant never fully “stops” (36:39) A patient story about resilience and asking for help National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/Check out our valued nbmtLINK resource books, some for sale, some free as downloadable, https://www.nbmtlink.org/shop/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.This content is provided for informational purposes only and is not intended to substitute for professional medical advice, diagnosis, or treatment. It is crucial to consult directly with a qualified healthcare professional regarding any medical conditions, treatment options, or other health concerns.The views and opinions expressed by the speakers are their own and do not necessarily reflect the official policy or position of the nbmtLINK. Unless otherwise stated in an official policy, the nbmtLINK does not endorse any specific treatments, products, or services mentioned by the speakers. Reliance on any information provided is solely at your own risk.The Marrow Masters Podcast is produced by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode of Marrow Masters, Peggy Burkhard talks with caregiver Ashlee Cramer about what caregiving really looks like during cancer, bone marrow transplant, and survivorship. Ashlee shares the story of her son Michael, who was diagnosed in 2020 with hepatosplenic T-cell lymphoma. Their family had already lived through cancer once before, when Ashlee's husband Patrice was diagnosed with large B-cell lymphoma in 2014 and later died at home in hospice, surrounded by his family. Ashlee explains that caregiving is often misunderstood. Caregivers are not saints who always feel strong, positive, or ready. Many are scared, exhausted, grieving, and trying to manage jobs, children, finances, appointments, medications, and the emotional weight of watching someone they love suffer. She says caregivers often feel pressure to do everything alone, but that pressure can lead to burnout and isolation. The conversation focuses on the reality that caregiving is not always temporary or predictable. For Michael, treatment moved quickly from diagnosis to hospitalization to transplant. He received a stem cell transplant from an anonymous donor, went into remission, and then developed serious complications, including engraftment syndrome, acute graft versus host disease (GVHD) , and chronic GVHD. Ashlee says Michael is a miracle, and while GVHD remains part of his life, the key word is living. Ashlee also talks about mental health for caregivers. She names anxiety, depression, post-traumatic stress disorder (PTSD), burnout, and loneliness as common experiences. She points out that many cancer centers offer support for patients, but caregivers often have to search for help on their own. Support groups, virtual programs, and caregiver resources can make a major difference because connection helps people feel less alone. A central message of the episode is that caregivers need care too. Ashlee encourages caregivers to take small pockets of peace when they cannot take a full day away. A shower, a breathwork practice, a walk outside, a cup of coffee, or a short hug from another caregiver can help. She also reminds caregivers to accept help. A meal train, a friend waiting in the hospital lobby, or someone offering a few minutes of support can ease the load. The episode ends with hope. Ashlee talks about post-traumatic growth, or PTG, and the idea that people do not have to bounce back to who they were before trauma. They can bounce forward. Michael and Ashlee continue to advocate, share their story through their podcast Michael and Mom Talk Cancer, and remind other caregivers that they are not alone. Thanks to this season's sponsors, Incyte and Sanofi. (00:00 Intro (04:05) Misconceptions about caregiving and why caregivers are not saints (05:30) Why caregivers should not be expected to do everything alone (07:00) The pressure to “stay strong” and how it can isolate caregivers (09:49) The reality of caregiving and how much it affects mental health (12:03) Work, family, sacrifice, and the myth of balance (16:40) Caregiver anxiety, depression, PTSD, burnout, and the need for support (20:40) Finding small “pockets of peace” when a full break is impossible (23:10) What Ashlee wishes she knew earlier about speaking up and asking questions (24:59) Why accepting help matters and how a meal train supported her family (34:09) Post-traumatic growth and the idea of bouncing forward instead of bouncing back National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/Check out our valued nbmtLINK resource books, some for sale, some free as downloadable, https://www.nbmtlink.org/shop/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.This content is provided for informational purposes only and is not intended to substitute for professional medical advice, diagnosis, or treatment. It is crucial to consult directly with a qualified healthcare professional regarding any medical conditions, treatment options, or other health concerns.The views and opinions expressed by the speakers are their own and do not necessarily reflect the official policy or position of the nbmtLINK. Unless otherwise stated in an official policy, the nbmtLINK does not endorse any specific treatments, products, or services mentioned by the speakers. Reliance on any information provided is solely at your own risk.The Marrow Masters Podcast is produced by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Today, Peggy Burkhard talks with Dr. Amar Kelkar of the Dana-Farber Cancer Institute about the medical side of survivorship after bone marrow, stem cell, or CAR-T transplant. The conversation begins with the important shift from the urgent “save my life” phase to the longer “protect my health” phase. Dr. Kelkar explains that this transition often starts around the 100-day mark, though timing varies by transplant center, geographical region and patient needs. A major theme is the need to restart routine care that may have been paused during transplant. Dental care, dermatology, ophthalmology, and primary care all become important again. Dental visits are especially important because oral graft-versus-host disease (GVHD) can cause dry mouth, irritation, cavities, and other problems. Skin checks matter because transplant can increase the risk of skin cancers. Dr. Kelkar stresses annual dermatology visits, sun protection, SPF 50 or higher, protective clothing, and smart decisions about sun exposure. Fatigue is another central topic. Dr. Kelkar describes post-transplant fatigue as different from normal tiredness. It can feel deep, physical, and mental, and it may last for months or even years. He encourages patients to pace themselves, listen to their bodies, and build activity back slowly. Returning to work also needs to be individualized. Some patients work remotely during treatment, while others may need extended disability or a gradual return. The episode also covers immune recovery and repeat vaccinations. Dr. Kelkar explains that after transplant, the immune system has been reset, and many childhood vaccines need to be repeated. Most programs begin revaccination around six, nine, or 12 months, depending on immune suppression and other factors. He reassures listeners that many patients have fewer vaccine symptoms early on because their immune systems are still rebuilding. Dr. Kelkar also reviews long-term screening and prevention. Survivors need routine cancer screenings, including mammograms, colonoscopies, lung cancer screening when appropriate, skin exams, and monitoring for thyroid or other changes. Metabolic health is also important. Steroids can affect blood sugar, transplant can change body composition, and quick weight loss often includes muscle loss. Nutrition support and exercise programs can help, and Peggy notes that Blood Cancer United offers nutrition services for patients and caregivers. Blood Cancer United's nutrition program provides free one-on-one consultations with oncology dietitians by phone or email. Bone health, hormone changes, sexual health, and early aging are also discussed. Dr. Kelkar explains that steroids, menopause, testosterone changes, vitamin D deficiency, and time indoors can affect bones. Many centers use DEXA scans and vitamin D supplementation. He also encourages patients to bring up sexual health concerns, including menopause symptoms, low testosterone, pain with intercourse, ulcers, or fear about resuming intimacy. The episode closes with practical advice for everyday life. Food restrictions often loosen around 100 days, but patients should reintroduce foods slowly and carefully. Raw foods, alcohol, tobacco, and inhaled smoke should generally be avoided, especially during the first year. Dr. Kelkar also emphasizes mental health support, counseling, and honest conversations with the medical team. Survivorship is a bumpy road, but the goal is to help patients regain control and thrive. Blood Cancer United Nutrition Offerings: https://bloodcancerunited.org/blood-cancer-care/adults/food-nutrition Thanks to this season's sponsors, Incyte and Sanofi. (00:00) Intro (01:16) Moving from acute treatment to survivorship (02:17) Dental, dermatology, ophthalmology, and routine care (05:45) Fatigue after transplant versus normal tiredness (08:35) Pacing yourself and avoiding setbacks (10:26) Returning to work after transplant (12:24) Resetting the immune system and repeat vaccinations (16:07) Secondary malignancy prevention and cancer screenings (18:59) Sun protection and skin cancer prevention (20:23) Metabolic health, blood sugar, and weight management (23:58) Bone health, vitamin D, DEXA scans, and early aging (29:32) Sexual health and hormonal changes (32:43) Everyday living after transplant (36:07) Psychological and cognitive hurdles in survivorship (38:16) Pulmonary function tests and liver monitoring (40:42) Closing thoughts National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/Check out our valued nbmtLINK resource books, some for sale, some free as downloadable, https://www.nbmtlink.org/shop/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.This content is provided for informational purposes only and is not intended to substitute for professional medical advice, diagnosis, or treatment. It is crucial to consult directly with a qualified healthcare professional regarding any medical conditions, treatment options, or other health concerns.The views and opinions expressed by the speakers are their own and do not necessarily reflect the official policy or position of the nbmtLINK. Unless otherwise stated in an official policy, the nbmtLINK does not endorse any specific treatments, products, or services mentioned by the speakers. Reliance on any information provided is solely at your own risk.The Marrow Masters Podcast is produced by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

When Kelly DiGiammo's son Brayden was 13 years old in early 2024 he developed troubling health symptoms, including going from being one of the fastest runners in the school to losing his breath and running very slowly, experiencing continuing colds, and then having a bout with the flu. Brayden was diagnosed late in February of that year with Acute Myeloid Leukemia. Brayden successfully completed a Stem Cell Transplant and has been in remission since May of 2024. Kelly and Brayden will talk about his journey which has been a successful one and Kelly will also talk about her experiences getting involved in advocacy work for the cause of Pediatric Cancer. 

Would like like to share feedback on this podcast? Or suggest another topic for us to explore? Click here, or email us at DocTalk@medstar.netOn this DocTalk episode, we chat with Dr. Jennifer Kanakry, the medical director of the Stem Cell Transplant and Cellular Immunotherapy Program at MedStar Georgetown University Hospital. Dr. Kanakry explains what types of lymphoma can be treated with CAR T-cell therapy. For an interview with Dr. Jennifer Kanakry, or for more information about this podcast, contact MedStar Georgetown University Hospital Manager Media Relations, Ryan.M.Miller2@Medstar.net. Learn more about Dr. Kanakry.For more episodes of MedStar Health DocTalk, go to medstarhealth.org/doctalk.

A young mum facing life threatening delays for cancer treatment may be forced to raise more than a million dollars for a stem cell transplant overseas. Loran Geddes, who is 29, was diagnosed with Leukaemia last year and needs a stem cell transplant for any chance of a cure. But a lengthy waitlist means her treatment keeps getting pushed out, significantly impacting her chance of survival. What was at first a six month wait, is now nine months. She's now in remission and must stay this way to get the transplant that is still six months off, leaving her in a dangerous limbo. Loran Geddes spoke to Lisa Owen. 

Dr. Alberto Cardoso Martins Lima shares how advances in therapeutics are changing the way we think about HSCT donor selection.AFDT LINK: https://amfdt.swoogo.com/histocompatability2026/home

Rich — a leukemia survivor, nurse practitioner, and longtime oncology clinician — to talk about what it's really like to survive cancer, rebuild your life after treatment, and live with long-term side effects.Rich was diagnosed with leukemia at age 28, underwent an allogeneic stem cell transplant at Dana-Farber / Brigham and Women's, and is now a 29-year survivor. His experience as both a patient and provider offers a rare, honest look at cancer survivorship, prostate cancer side effects, sexual health, mental health, and post-traumatic growth.In this conversation, we cover:What it's like to be told you have leukemia in your 20sStem cell transplant and long-term survivalTurning cancer into purpose and becoming an oncology NPCommon prostate cancer side effects (urination, bowel changes, erectile dysfunction)How doctors actually manage these symptomsSexual health after cancer treatmentMental health, grief, and post-traumatic growthHow to rebuild your life after active treatmentThis episode is for patients, survivors, caregivers, and anyone navigating life after a cancer diagnosis.

Stem cell transplant patients face significant GI challenges that make nutrition support complex—and critical. In this episode, I'm joined by Katie Harper, MS, RD, CNSC, an expert in oncology and blood and marrow transplant nutrition, to break down best practices for transitioning patients from parenteral nutrition (PN) to enteral nutrition (EN).We cover:• When nutrition support is needed during transplant• Key challenges with PN• How to assess readiness for EN• Practical strategies for successful PN-to-EN transitions• The importance of interdisciplinary collaborationA must-listen for dietitians and clinicians supporting stem cell transplant patients.

Join host Dr. Nikolaos Papadantonakis as he welcomes Dr. Colin Vale from Winship Cancer Institute of Emory University and Dr. Nancy Luna Torres from Moffitt Cancer Center to discuss the fundamentals of allogeneic hematopoietic stem cell transplantation for MDS patients.  Our experts break down complex medical concepts into easy-to-understand language, helping patients make informed decisions about this important treatment option.

In this follow-up episode,  Dr. Nikolaos Papadantonakis continues the conversation with Dr. Colin Vale from Winship Cancer Institute of Emory University and Dr. Nancy Luna Torres from Moffitt Cancer Center, diving deeper into advanced transplant topics. This episode is ideal for patients and families who want to understand the nuances of transplant care and post-transplant management.

After the 2025 American Society of Hematology (ASH) Annual Meeting had passed, the  data were out, and the hematologist/oncologists of the world had time to digest the practice changes that awaited them upon their returns home. Rahul Banerjee, MD, FACP, and Brooke Adams, PharmD, BCOP, took part in an X Spaces discussion hosted by CancerNetwork® in collaboration with The American Society for Transplantation and Cellular Therapy (ASTCT) to highlight these potential changes. Adams and Banerjee discussed abstracts from the meeting, including the phase 3 MajesTEC-3 trial (NCT05083169), which evaluated teclistamab-cqyv (Tecvayli) plus daratumumab (Darzalex) in patients with relapsed/refractory multiple myeloma who progressed on at least 1 prior line of therapy.1 A significant progression-free survival benefit was observed with the experimental combination compared with standard of care in this population. They also discussed data from cohort A of the phase 2 IFM2021-01 trial (NCT05572229), which evaluated subcutaneous teclistamab in combination with subcutaneous daratumumab in patients with newly diagnosed multiple myeloma. Results demonstrated that the combination was effective and safe in the frontline treatment of patients who were ineligible for transplant.2 The discussion also covered the broader treatment landscape, as the experts compared the use of bispecific antibodies with BCMA-directed CAR T-cell therapies. Frontline bispecific strategies for transplant-ineligible populations were also topics of conversation, as well as post-transplant consolidation with bispecifics. Ultimately, they stated that multiple myeloma care is undergoing a paradigm shift toward deeper minimal residual disease negativity, possible treatment de‑escalation, and even serious use of the word “cure” for the disease. Banerjee is an assistant professor in the Clinical Research Division at the Fred Hutchinson Cancer Center, and Adams is a clinical pharmacist in the Department of Stem Cell Transplant and Cellular Therapy and coordinator of the PGY-2 Oncology Residency at Orlando Health. Both are also members of the ASTCT content committee. References Mateos M-V, Bahlis N, Perrot A, et al. Phase 3 randomized study of teclistamab plus daratumumab versus investigator's choice of daratumumab and dexamethasone with either pomalidomide or Bortezomib (DPd/DVd) in patients (Pts) with relapsed refractory multiple myeloma (RRMM): Results of majestec-3. Blood. 2025;146(suppl 2):LBA-6. doi:10.1182/blood-2025-LBA-6 Manier S, Lambert J, Marco M, et al. A phase 2 study of teclistamab in combination with daratumumab in elderly patients with newly diagnosed multiple myeloma: the IFM2021-01 teclille trial, cohort A. Blood. 2025;146(suppl 1):367. doi:10.1182/blood-2025-367

In this episode, we sit down with Lorri Pimentel of Santa Rosa, California, a resilient survivor who shares her deeply personal journey through breast cancer, acute myeloid leukemia (AML), and a life-saving bone marrow transplant. We explore not only the medical milestones but also the practical and emotional realities of navigating treatment and recovery, especially in the context of caregiving during the COVID-19 pandemic.Lorri opens by walking us through her diagnosis timeline: first with DCIS breast cancer in 2016, followed by an AML diagnosis in 2019. She underwent intense chemotherapy and, after a relapse, received a stem cell transplant in March 2021. Her story is not only one of medical complexity but also of personal upheaval—she was in the middle of a divorce and raising three children, with limited family caregiving options. Her caregivers were her friends and former work colleagues, who rotated week by week to support her recovery.We dive into Lorri's insights and hard-earned lessons about caregiving and post-transplant life. She stresses the importance of flexibility in caregiver scheduling, being prepared for early hospital discharge, and having a list of essential medical contacts readily available. She advises caregivers to undergo thorough training, keep detailed records for outpatient visits, and maintain strict medication management practices.Lorri doesn't shy away from sharing her missteps. She discusses her experience with Graft-versus-Host Disease (GvHD), the dangers of sun exposure, and complications like mucositis and insomnia. Her tips—like using a water pick, prescription mouthwash, fluoride toothpaste, and avoiding self-medicating with cannabis—are based on lived experience. She also shares less obvious insights, such as the need for UV-protective clothing, avoiding rice leftovers, and managing dry eyes with serum-based drops not yet FDA-approved.Transportation and social isolation were also major themes. Lorri emphasizes the importance of arranging reliable rides to appointments and finding indoor outlets for creativity and community. She found healing in watercolor art, music, yoga, and support groups. Her volunteer work with LLS, now Blood Cancer United, and NMDP reflects her dedication to mentoring others on the same path.We wrap up by discussing Lorri's present-day life. Now more than four years post-transplant, she's active, creative, and grounded in gratitude. Her final message is one of hope and purpose: bone marrow transplant recovery is slow, but it's life-changing, and each day is a gift worth sharing.This season is sponsored by Sanofi: https://www.sanofi.com/And Jazz Pharmaceuticals: https://www.jazzpharma.com/ National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.To participate in the GVHD Mosaic, click here: https://amp.livemosaics.com/gvhd Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Mafalda de Freitas, megaplastics program director at the Center for Marine Debris Research at Hawaiʻi Pacific University, talks about Hawaiʻi's only marine debris recycling center; Donor Mariel Tadena, stem cell recipient Nicole Fabela, and Erika Sevilla, spokesperson for the National Marrow Donor Program, share their stem cell story

In this episode, host Jonathan Sackier is joined by Emanuele Angelucci, Director of Hematology and Cellular Therapies and Director of the Stem Cell Transplant and Cellular Therapies Program at the Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Ospedale Policlinico San Martino Hospital in Genoa, Italy.   Timestamps   00:00 – Introduction 02:14 – The future of stem cell transplantation 03:15 – What continues to drive Emanuele in his work 05:40 – Donation of haematopoietic stem cells 10:00 – Gene therapy for haemoglobinopathies 11:40 – Will stem cell transplantation remain central in treating thalassaemia and sickle cell disease? 14:14 – Emanuele's work on iron overload and toxicity 16:53 – Current landscape for haemoglobinopathies 22:11 – Key recommendations in the most recent clinical guidelines for haemoglobinopathies  25:00 – Promising developments on the horizon for patients with haemoglobinopathies  28:00 – Emanuele's key takeaways 

In this episode, host Jonathan Sackier is joined by Steven Okoli, Honorary Senior Clinical Lecturer at Imperial College London. From leading the UK's first adult stem cell transplant trial for sickle cell disease to driving innovation in AI-guided transfusion strategies, Okoli shares how clinical research, patient advocacy, and equity-driven care are reshaping the landscape of haemoglobinopathies in the UK and beyond.  Timestamps  00:00: Introduction  01:58: Quickfire round  09:09: Pioneering adult stem cell transplant in sickle cell  11:41: Combining AI and genetics for blood transfusion  13:58: Systemic disparities in sickle cell  20:58: Education and advocacy  23:30: Non-cancerous blood disorders  25:18: What's next in sickle cell?  27:27: Okoli's three wishes for healthcare  

We do a check in to see what the update with Brooke getting a Stem Cell Transplant is and Monty went to a pain rehab! We also chat about how we talk to our kids about chronic illness and Brooke has a cracking tip that might make it a little less scary for our kids.See omnystudio.com/listener for privacy information.

In this episode, we speak with Emily Long Sarro, a board-certified family nurse practitioner specializing in adolescent and young adult (AYA) care at Memorial Sloan Kettering Cancer Center. We focus on the unique challenges AYAs face before, during, and after a stem cell transplant. Emily shares how this age group, defined as 15 years old to 39 years old by the National Cancer Institute, is often overlooked in the healthcare system, stuck between pediatric and adult care settings. They're navigating identity, relationships, careers, and independence—while also managing a serious illness, which can disrupt or halt life milestones.We discuss how Emily approaches AYA care with a holistic mindset—merging clinical treatment with emotional and mental health support. She emphasizes the importance of granting young patients autonomy and private space, especially when families may unintentionally overstep. She urges healthcare providers to always include mental health support in the treatment plan, noting that anxiety, depression, and even PTSD are common in this group, both during and long after treatment.Emily also stresses the need for daily coping tools like journaling, movement, and meditation to supplement infrequent counseling sessions. She encourages us to create trust by really listening, especially since many AYAs feel dismissed in early diagnostic stages due to their age.We then dive into critical but often unspoken topics: fertility preservation, sexual health, and survivorship. Emily outlines time-sensitive fertility options and highlights the emotional toll if these aren't addressed early. She covers the hidden costs of care and offers resource suggestions like Livestrong and Cancer and Careers. She also calls attention to "silent disabilities" that persist post-transplant and affect career and daily function, emphasizing self-advocacy in the workplace. Coworkers and others may not "see" these limitations, but accommodations are often necessary.We discuss milestones missed due to treatment and the emotional weight of watching peers move on through social media. Emily suggests practical ways to stay socially connected, such as virtual events and platforms like Cancer Buddy. For caregivers, she reminds us that support often means just being present and handling small tasks that feel overwhelming to the patient.  It's important to hold space for patients' sadness over missing milestones, but when appropriate, the big picture remains: they may be sacrificing a few milestones now to experience many more later.The episode closes with a deeply moving survivor story—a young man from The Bronx who overcame mistrust in the medical system, underwent a transplant, and now runs a thriving music production business. His resilience and transformation encapsulate the hope and strength that defines this patient group.More:Marrow Masters Season 9, Episode 2, with fertility resources in Show Notes: https://marrowmasters.simplecast.com/episodes/preserving-fertility-through-cancer-treatmentCancerCare – https://www.cancercare.orgImerman's Angels – https://imermanangels.orgLivestrong Fertility – https://livestrong.org/how-we-help/livestrong-fertility/Worth the Wait – https://worththewaitcharity.com/Maggie's Dream (Fertility Preservation Assistance)–https://www.teammaggiesdream.org/Cancer and Careers – https://www.cancerandcareers.orgCancer Buddy App (Bone Marrow Foundation) –https://bonemarrow.org/support-and-financial-aid-2/support/about-cancerbuddyThanks to our Season 17 Sponsors:Leukemia and Lymphoma Society (LLS): https://lls.org/and Incyte: https://incyte.com/ National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.To participate in the GVHD Mosaic, click here: https://amp.livemosaics.com/gvhd

In this incredible episode of Marrow Masters, we sit down with Kayla West, a stem cell donor from Texas, and Miriam Bauer, the mother of a young leukemia survivor Miley, from Oklahoma. This story is a deeply emotional journey of hope, resilience, and a connection that transcends bloodlines. Kayla and Miriam take us through the entire transplant process from both perspectives: the donor stepping up during a pandemic, and the caregiver navigating a life-threatening diagnosis in a child.We begin with Kayla's decision to join the donor registry after a chance encounter with DKMS at a Goo Goo Dolls concert. She didn't expect to be called to donate, but when she was, during COVID lockdown, she jumped at the chance to help someone—anyone—in need. That “anyone” turned out to be Miley, an eleven-year-old girl who had been diagnosed with acute myeloid leukemia (AML) and urgently needed a transplant after two brutal rounds of chemotherapy.Miriam recounts those terrifying early days at St. Jude, from the moment of diagnosis through the chaos of the early pandemic lockdowns. She was Miley's only caregiver during a 248-day hospital stay. Her story is filled with moments of heartbreak and triumph, from failed chemo rounds to the joy of reaching remission and finding a viable donor in Kayla. We learn how transplant coordination works, how donor cells were frozen and shipped during COVID, and how little details—like celebrating donor day or choosing a transplant date that coincides with family birthdays—brought joy in dark times.Post-transplant, Miley's life has been a mix of recovery and lingering health effects, but she's thriving. Miriam emphasizes advocacy, honesty, and self-care for caregivers. Kayla, for her part, reflects on the overwhelming emotion of learning she was a match, undergoing all the testing during COVID, and then finally meeting the recipient of her cells in an unforgettable reunion in New York. The two families, now bonded for life, meet regularly and have built a deep friendship.  Next up: A trip for Kayla's family to Oklahoma to experience a powwow with Miriam, Miley, and their family!The videos below will have you reaching for the tissues and hopefully inspire many to get swabbed.Kayla also shares her decision to launch a nonprofit, SETX Leukemia Organization, focused on educating communities and recruiting new donors. Her goal is to prevent other families from facing what Miriam's did—wondering if there will be a match in time. Kayla's drive, born from her experience, continues to ripple outwards as she recruits more potential donors at local events with DKMS support.This episode isn't just about survival—it's about connection, purpose, and what can happen when strangers become family through an act of extraordinary generosity.SETX Leukemia Organization (Kayla's nonprofit): https://setxleukemia.org/DKMS (Be The Match partner organization): https://www.dkms.orgDKMS Video about Kayla, Miley, and Miriam: https://www.youtube.com/watch?v=sNhwRxXMbw8Thanks to our Season 17 Sponsors:Leukemia and Lymphoma Society (LLS): https://lls.org/and Incyte: https://incyte.com/ National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.To participate in the GVHD Mosaic, click here: https://amp.livemosaics.com/gvhd

Official Emailtalkinwithtopher@gmail.comTopher's Social Media(linktr.ee) ⁠⁠https://linktr.ee/talkinwithtopher⁠⁠(instagram) ⁠⁠https://www.instagram.com/talkinwithtopher/?hl=en⁠⁠(twitter) ⁠⁠https://twitter.com/_conderman⁠⁠(snap chat) ⁠⁠https://www.snapchat.com/add/cconderman?share_id=HiV14moKPns&locale=en-US⁠⁠(tik tok) ⁠⁠https://www.tiktok.com/@talkinwithtopher?lang=en⁠⁠(Facebook) ⁠⁠https://www.facebook.com/christopher.conderman⁠⁠Time Stamps(00:00:00) Start(00:01:54) Puppy Love(00:04:56) A23A on the move(00:11:23) What happens all the ice melts(00:17:23) China's endless power, power plant(00:20:03) Meta worked with China in Censorship(00:26:07) Stem Cell transplant restores vision(00:29:56) Clean Cocaine(00:33:41) Trump Excepting the Trojan Horse from Qatar(00:38:04) Putin Reveals Tartaria was Real(00:43:17) There were no planes(00:47:29) Controlled Demolition Squib Blow OutEpisode Linkshttps://www.bbc.co.uk/news/resources/idt-f4de435a-d215-4a7c-86e9-9b838701c993https://youtu.be/VbiRNT_gWUQ?si=qH5v9uDC0ZiQpvp5https://www.sustainability-times.com/energy/the-us-on-high-alert-chinas-largest-nuclear-reactor-passes-final-test-as-global-power-tensions-explode/https://www.cbsnews.com/news/meta-whistleblower-testimony-senate-judiciary-subcommittee/https://www.wcvb.com/article/stem-cell-transplant-treatment-restores-vision/64409863https://abcnews.go.com/Politics/doj-coast-guard-bust-45000-pounds-cocaine-tied/story?id=120642241https://www.google.com/imgres?imgurl=https://www.techspot.com/images2/news/bigimage/2023/09/2023-09-12-image.jpg&tbnid=i7ds8lmYELSvaM&vet=1&imgrefurl=https://www.cbsnews.com/news/qatar-jet-trump-boeing-pentagon/https://x.com/Whiplash437/status/1924311751492808956https://www.instagram.com/reel/DHvgNxuuP5Z/?utm_source=ig_web_copy_linkhttps://x.com/BGatesIsaPyscho/status/1926325690506297632

Sheila Romanski is with us today after overcoming two diagnoses of breast cancer and the removal of a tumor in her left shoulder thanks to an autologous stem cell transplant.  She tells the @CancerInterviews podcast her initial of Stage 1A breast cancer in 1996 came after her doctor suggested a routine mammogram at age 36 when at the time mammograms were not performed on women that young.  Radiation treatment successfully addressed that diagnosis, but the following year, the cancer had metastasized to her shoulder.  That brought on the stem cell transplant, plus chemotherapy and more radiation.  All seemed well until 2008 when the breast cancer returned as Stage 4 triple negative infiltrating ductal carcinoma.  Shiela opted for a double mastectomy with reconstruction, which was followed by a second, more aggressive form of chemotherapy.  She has been pronounced NED (No Evidence of Disease), and now enjoys a healthy lifestyle, leading a non-profit that aids cancer victims.   Sheila Romanski advises everyone to do self-examinations for breast cancer.  She admits had she done so, her breast cancer would have been caught sooner.  In 1996, it was rare that 36-year-old women went in for routine mammograms, but Sheila's doctor suggested such an exam.  Thanks to that suggestion, a 2cm tumor was found.  She underwent a lumpectomy and radiation treatment.   While it appeared cancer was in her rear-view mirror, in 1997, a lump was found in her collar bone area.  That was treated with four chemotherapy treatments and autologous stem cell transplant, a procedure involved her own stem cells.  The chemo and the transplant last four months.   For Sheila, this time in her life was very challenging.  She was no only battling cancer, but she was raising four small children.  However, she says she was able to get through because of support from her friends and her church, and because attending to the needs of her kids took her mind off cancer.   Sheila's health appeared to be on the right track until 2008 when another routine mammogram revealed micro-calcifications in the same breast as her original diagnosis.  She decided a double mastectomy would be her best option. It would include a procedure called a diep flap, which involves taking skin from other parts of the body.  However, her surgeon said Sheila would have to lose twenty pounds before diep flap could be performed.  It took Shiela ten years to lose the weight and by that time, her surgeon said she no longer performed diep flap.  However, she said she could get Sheila “fixed up” and in 2021, thirteen years after mastectomy, reconstruction was complete.   Sheila Romanski has gone on to found Crystal Roses, a non-profit that seeks to aid those diagnosed with cancer.   Additional Resources:   Support Group:   Crystal Roses  https://www.crystalroseshelps.com    

We sat down and recorded before Brooke headed off to see her neurologist. Brooke has had three different types of treatments for MS and none have worked as they would have hoped. Stem cell transplants are occasionally done in Australia but have a super strict criteria you need to meet to be considered. We chat about what it is exactly and if Brooke is a candidate. This story is unfolding in real time and we will keep you updated. See omnystudio.com/listener for privacy information.

This week's episode will be focusing on Hematopoietic Stem Cell Transplant. We welcome our guest  Dr. Jeff Auletta, Senior Vice President, National Marrow Donor Program, and Chief Scientific Director,Center for International Blood and Marrow Transplant Research. Part 2 discusses conditioning regimens, graft-vs-host disease, toxicities, and Dr. Auletta's career path.

This week's episode will be focusing on Hematopoietic Stem Cell Transplant. We welcome our guest  Dr. Jeff Auletta, Senior Vice President, National Marrow Donor Program, and Chief Scientific Director,Center for International Blood and Marrow Transplant Research. Part 1 discusses important basics including what a transplant is, types of transplant & associated risks, types of donors, how to find a donor, and barriers/inequities of finding a donor.

In this week's episode we'll learn more about how phosphoseryl-tRNA kinase inhibition promotes cell death in acute myeloid leukemia, or AML; APOE gene variants and their association with post-hematopoietic stem cell transplant outcomes in AML; and pathways by which chronic inflammation and oxidative stress may lead to cardiomyopathy in patients with sickle cell disease.Featured Articles:PSTK inhibition activates cGAS-STING, precipitating ferroptotic cell death in leukemic stem cells Common Hereditary Variants of the APOE Gene and Posttransplant Outcome in Acute Myeloid Leukemia 17R-Resolvin D1 Protects Against Sickle Cell Related Inflammatory Cardiomyopathy in Humanized Mice 

A cancer diagnosis at any age is scary and life changing, but receiving this news the you are at a point in your life where having children, starting a family or growing your family is on your mind, raises a different set of challenges. Saskatoon's Prairie Cancer Fertility Preservation charity supports cancer patients when it comes to fertility challenges. Helping patients navigate fertility issues during a cancer diagnosis is something Dominique Paulgaard and Lierin Baerg do in their roles as nurses at Royal University Hospital and with their charity, Prairie Cancer Fertility Preservation. The charity was started three years by a group of oncology nurses in Saskatoon and today features Jessica Smith, Taylor Huang, Lierin Baerg and Dominique Paulgaard as its members. The purpose of Prairie Cancer Fertility Preservation is to preserve the ability for cancer patients to have children. As I learned from Lierin and Dominique, this can either be through sperm or egg preservation, and as you are about to hear, it can be quite the journey. Lieren as been a Registered Nurse at Royal University Hospital's Inpatient Cancer and Stem Cell Transplant unit for the past 10 years. Dominique has been a nurse in the same unit for 13 years. They both have families with young children and find the time to run this charity.How the charity works, why it means so much to them, and what conversations are like with their patients when it comes to fertility are topics we cover in our conversation. We also discuss how overwhelming it is for someone who has just received a cancer diagnosis to think about if they want to preserve their ability to have children in the future and the financial challenges that come with their decision.Prairie Cancer Fertility Preservation has a fundraising event on Saturday, March 15th at Crossmount Cider Company. Tickets are 50 dollars and Saskatoon's Ross Nielsen will be playing live sets of music. You can learn more by following Prairie Cancer Fertility Preservation on Facebook and Instagram, or click this link to purchase tickets.You can listen to YXE Underground wherever you find your favourite including Apple Podcast, Spotify, Goodpods or on yxeunderground.com. Please feel free to leave a 5-star review if you like what you hear. These positive reviews help the podcast show up in more podcast feeds so I really do appreciate the support. I also want to let you know of an exciting event I am working on with the Remai Modern. Please mark April 17th on your calendar as that's when YXE Underground will be presenting a movie at the Remai Modern's lovely theatre beginning at 7pm. This is thanks to Kyle Zurevinski, who runs the theatre programming at the Remai, and his generous spirit. We will be showing the short film Molly Schikosky and I made last summer celebrating the podcast followed by the Pixar classic, Wall-E because it's one of my favourite movies of all time and I think it connects nicely to YXE Underground in meaningful ways. The Remai does this with other community organizations who select a movie for the public to watch for free and it's really cool to partner with the gallery in this way. Plus, it's free to attend!So I would love to see you on the night of Thursday, April 17th, to celebrate the podcast and watch one of the best films of the past 20 years.Thank you for continuing to support a local, independent podcast here in Saskatoon.Cheers...Eric  Host, Producer, Editor: Eric AndersonTheme Music: Andrew DicksonWebsite: https://www.yxeunderground.comRecorded: On Treaty 6 Territory and the traditional homeland of the Metis

Pippa speaks to Amy Brand who is only a few days way from going into hospital for a stem cell transplant – but she is so passionate about raising awareness of this issue that she was adamant we needed to speak to her ahead of that procedure.See omnystudio.com/listener for privacy information.

In this episode, depth + somatic psychotherapist, and The Whole Paradox Host, Molly Mitchell-Hardt interviews Yoga Nidra guide, cancer survivor, and podcast host Ayla Nova. They talk about:The yogic journeyCancer diagnosis, dancing with death, and deep surrenderFinding and falling in love with Yoga NidraWorking with the narrative of "good" and "bad" versus non-dualityThe wheel of samsaraSitting with shadow and being "not okay" within spiritual communitiesRelationship with fearand so much more...Follow us @mollymitchellhardt and @thewholeparadoxMolly's Offerings:To inquire about 1:1 work or about Molly's Sacred Motherhood Online Support Group, schedule a free consultation or email mollymitchellhardt@gmail.comFind Ayla Nova:Follow Ayla on instagramVisit Ayla's website and find her Yoga Nidra trainingThis podcast was produced in association with Channel the Sun by Kevin Joseph Grossmann.  Musical stylings by Kevin Joseph Grossmann.

BUFFALO, NY - February 10, 2025 – A new #casereport was #published in Volume 16 of Oncotarget on February 5, 2025, titled “A case report of donor cell–derived hematologic neoplasms 9 years after allogeneic hematopoietic cell transplantation." In this case report, Aleksandra Mroczkowska-Bękarciak and Tomasz Wróbel from Wroclaw Medical University describe a rare and serious complication after a stem cell transplant. The case involves a patient who, nine years after receiving a stem cell transplant for acute myeloid leukemia (AML), developed a new, aggressive blood cancer originating from donor cells. Despite receiving treatment, the disease progressed to myelodysplastic syndrome/acute myeloid leukemia (MDS/AML), ultimately leading to the patient's death. Stem cell transplants are a life-saving treatment for many blood cancers, including AML. While relapse of the original cancer is the most common concern, this case highlights another rare but serious complication: the development of donor cell-derived hematologic neoplasms (DCHN). The report details the case of a 23-year-old woman who remained in remission for nearly 10 years following a successful hematopoietic stem cell transplant from an unrelated donor. However, she later developed a new form of leukemia, driven by genetic mutations in the ASXL1, SETBP1, and EZH2 genes—biomarkers linked to highly aggressive blood cancers. Over the next two years, the disease progressed despite intensive treatment, ultimately proving fatal. This case highlights the need for continued monitoring of transplant recipients, even years after the procedure. Although DCHN is extremely rare, its occurrence raises critical questions about the process by which donor cells transform into leukemia. Some stem cell donors may unknowingly carry genetic mutations that are harmless in their own bodies but could trigger cancer in recipients. Additionally, factors such as immunosuppressive therapy, bone marrow stress, and transplantation procedures may contribute to these rare but deadly outcomes. “Early diagnosis and intervention are crucial to improving patient prognosis.” Ongoing research is focused on improving donor screening methods to help predict and prevent these complications. In the future, routine genetic testing for stem cell donors could become a standard part of the transplant process, helping clinicians identify potential risks before transplantation. More studies are needed to fully understand why donor-derived cancers develop and how they can be prevented. With continued progress in precision medicine and genetic diagnostics, researchers aim to make stem cell transplants safer and more effective for all patients. DOI - https://doi.org/10.18632/oncotarget.28686 Correspondence to - Aleksandra Mroczkowska-Bękarciak - omroczkowska@interia.pl Video short - https://www.youtube.com/watch?v=G2zd0UqWzeE About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Just the ongoings of my life so far. He is day 8 post stem cell transplant. Giving some tips on how to create an organized medication system and tips on how to prepare for Stem Cell Transplantation. Enjoy.

In today's episode, we talk with Krista Wood, a registered nurse with the Cell Therapy and Transplant Program at Victoria General Hospital in Halifax, Nova Scotia (Canada). Krista shares her invaluable insights and experiences working with patients dealing with chronic graft-versus-host disease (GVHD), a common complication following stem cell transplants. Our discussion delves into the importance of communication, post-transplant care, and finding joy and purpose during survivorship.Krista emphasizes that early detection and treatment of GVHD are critical. She encourages patients to report any changes, no matter how minor they may seem, and reassures them that healthcare teams are there to help. This open communication is vital, as post-transplant life can be overwhelming with fears of relapse or complications. Ensuring patients have direct access to their care team can ease their anxieties and foster trust.Routine health checks, like blood work and pulmonary function tests, play a crucial role in monitoring potential complications. Krista explains the importance of tracking liver enzymes, bone density, and lung function to catch and address issues early. She underscores that post-transplant care goes beyond the transplant itself, extending to overall health maintenance, including routine screenings like mammograms, dental care, and colorectal exams.Reconnecting with life post-transplant is another important theme. Krista encourages patients to rediscover the activities they loved before their illness, whether it's returning to work, volunteering, or pursuing hobbies. Work and social engagement provide purpose and can aid emotional recovery. For those who can't return to work, finding alternative ways to contribute, such as volunteering with organizations like the Leukemia & Lymphoma Society or HealthTree, can offer fulfillment and connection. (Note: the National Bone Marrow Transplant Link (nbmtLINK) has a peer mentor program as well, email info@nbmtlink.org if you'd like to be a peer or need a peer mentor. )Preparing for transplant and understanding GVHD beforehand is crucial. While some patients prefer to know everything, others may only want the basics. Krista and her team provide consistent education in manageable increments to help patients absorb key information. She explains factors that increase the risk of GVHD, such as donor characteristics and patient preconditioning, and stresses the importance of entering the transplant process in the best possible physical shape.Krista also highlights the importance of addressing sensitive topics like sexual health, which many patients are reluctant to discuss. She brings up these issues proactively, ensuring patients feel supported and have access to necessary resources.Finally, Krista shares stories of hope, including patients who, despite long-term challenges, have regained a sense of normalcy and fulfillment. She reminds us that while every patient's journey is unique, resilience and adaptation are common threads in their recovery.This episode is a testament to the critical role nurses like Krista play in guiding patients through this complex medical journey, offering care, education, and encouragement every step of the way.More:Leukemia & Lymphoma Society: https://www.lls.orgHealthTree Foundation: https://www.healthtree.orgGVHD Alliance: https://www.gvhdalliance.orgLink to LLS free Nutrition Consultations: https://www.lls.org/managing-your-cancer/food-and-nutritionThank you to our sponsors. This season is supported by a healthcare contribution from Sanofi  https://www.sanofi.com/ National Bone Marrow Transplant Link - (800) LINK-BMT, or (800) 546-5268.nbmtLINK Website: https://www.nbmtlink.org/nbmtLINK Facebook Page: https://www.facebook.com/nbmtLINKFollow the nbmtLINK on Instagram! https://www.instagram.com/nbmtlink/The nbmtLINK YouTube Page can be found by clicking here.To participate in the GVHD Mosaic, click here: https://amp.livemosaics.com/gvhd

Send us a textThe MedStar Georgetown University Hospital Stem Cell Transplant and Cellular Immunotherapy Program is the only adult, FACT-accredited program in the Washington, D.C., area. We give patients with cancers affecting the blood or immune system and other disorders access to life-saving treatment options not otherwise available in our region. These include:·       Allogeneic stem cell transplant·       Autologous stem cell transplant·       CAR T-cell therapyAlaa Ali, MD, MSC, is a clinician, instructor, and investigator in clinical and translational research at MedStar Georgetown's Stem Cell Transplant and Cellular Immunotherapy program. Concurrrently, he holds the position of Assistant Professor at Georgetown University School of Medicine.For an interview with Dr. Ali, or for more information about this podcast, contact MedStar Georgetown University Hospital Manager Media Relations, Ryan.M.Miller2@Medstar.net. Learn more about Dr. Ali. For more episodes of MedStar Health DocTalk, go to medstarhealth.org/doctalk.

Dr. Amy Rothenberg, a respected naturopathic physician and three-time cancer survivor, shares her story of multiple cancer diagnoses and treatments. Her most recent treatment was a stem cell transplant in 2024 for acute leukemia. Dr. Rothenberg gives valuable insights into integrative cancer care, the importance of gut health, and practical tips for caregivers. The conversation also emphasizes the significance of maintaining a healthy lifestyle and seeking open-minded, collaborative healthcare providers. Tune in for an informative and inspiring discussion on navigating cancer care holistically.Link to Dr. Rothenberg's social media and websiteBe The Match Program - Becoming a stem cell donorWhat is a Stem Cell Transplant? NIH explanationTips for Caregivers of Patients — a guest blog post by Dr. RothenbergUnderstanding Cancer-Related FatiguePrevious podcast episodes :Dr. Amy Rothenberg's initial interview with usCancer-Related FatiguePrebiotics (Microbiome stuff)Chemotherapy-Induced NeuropathySupport the showOur website:https://www.thecancerpod.com Email us: thecancerpod@gmail.comJoin our growing community! We are @TheCancerPod on: Instagram Twitter Facebook LinkedIn THANK YOU for listening!

In this episode of your third favourite, above average, but infinitely curious podcast DIMED OUT... The months, weeks, and days are counting down until I head to Puebla, Mexico for HSCT treatment. In this second of a two parter, I go through my mental/emotional state and the practical preparation ahead of my Stem Cell Transplant. Follow Me on the Gram' https://www.instagram.com/iammalfoster/ Kofi (or Tea?) https://ko-fi.com/dimedout DIMED OUT is an anthropological Podcast dedicated to exploring the mysteries and meaning of life. An audio kaleidoscope of culture and society, alternative lifestyles and life experiences. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dimedout/message --- Send in a voice message: https://podcasters.spotify.com/pod/show/dimedout/message

In this Nutritional Therapy and Wellness Podcast episode, host Jamie Belz interviews Rachel Ballard, an RN who wasn't willing to accept the prognosis of a slow, painful, premature death. Rachel is a Registered Nurse, farmer, and Food As Medicine teacher who is currently completing her Nutritional Therapy Practitioner (NTP) certification. After battling back from a rare, paralyzing autoimmune disease, she's helping individuals use food as a tool so they can fight back against chronic conditions and defy the odds. A lover of British television dramas, raising medicinal plants, and scratch cooking, Rachel lives on her Kentucky cattle farm with her husband of twenty-three years and two teenage children. In talking with Jamie, Rachel walks us through her declining health, eventual diagnosis of CIPD (Chronic Inflammatory Demyelinating Polyneuropathy), and her long road to recovery. 04:50 – Symptoms and red flags leading up to diagnosis: Hashimoto's, muscles in eye, limp leg, loss of strength, paralysis, felt like she was “on fire” 07:10 – CIPD Diagnosis with Central Nervous Symptom Overlap causing issues with vision, hearing, digestion, bowel and bladder control, and promoting cardiac arrhythmia 9:00 - IVIG (Intravenous Immunoglobulin) Treatment, Plasmapheresis, Stem Cell Transplant, slow decline 10:10 – Five years to live 11:02 – Subcutaneous IVIG Therapy Failed 13:02 – Hitting the point of desperation, looking at natural medicine for the first time, found the wrong natural medicine professionals for her preference and bio-individuality at the time 19:34 – Buying-in on the alternative approach 21:30 – Corruption in science, “follow the money” 22:30 – Working with an NTP, starting with digestion, making slow progress 27:53 – New hope, new career 30:31 – Bioindividuality 31:57 – TALKING ABOUT FOOD! Simple swaps, things to buy 40:17 - Mindset 42:04 – Car analogy 43:15 – Rachel's list of reversed symptoms/conditions 44:21 – Last question As you'll hear, taking the first steps into a more natural approach to wellness can be challenging, frustrating, expensive, and a little “weird.” Rachel shares how she didn't find any luck or answers with the alternative medicine practitioners she initially saw.* Her story is fun, relatable, and inspirational for those suffering from illness, as well as those looking to peek over the fence from the world of conventional medicine. You can find Rachel's food blog at www.feastandfarm.com. Please SUBSCRIBE and visit www.nutritionaltherapy.com/podcast to record a question for the show. *Not all practitioners of each title are created equally. Remember to give multiple practitioners under one umbrella a chance. This is true for both allopathic and alternative care. :)

One marker of the distance we've traveled in palliative care is the blossoming evidence base for the field. Ten years ago we would have been hard pressed to find 3 clinical trial abstracts submitted to the annual meeting, much less high quality randomized trials with robust measures, sample sizes, and analytics plans.  Well, as a kick off to this year's first in-person State of the Science plenary, held in conjunction with the closing Saturday session of the AAHPM/HPNA Annual Assembly, 3 randomized clinical trials were presented. Today we interview the authors of these 3 abstracts about their findings: Tom LeBlanc about a multisite trial of palliative care for patients undergoing Stem Cell Transplant for blood cancers (outcomes = quality of life, depression, anxiety) Kate Courtright about a pragmatic trial of electronic nudges to prognosticate and/or offer comfort-focused treatment to mechanically ventilated ICU patients/surrogates (outcomes = lengths of stay, hospice, time to discontinuation of life-support) Corita Grudzen on a pragmatic trial of two palliative care approaches for patients with advanced cancer or organ failure discharged from the ED: a nurse-led telephone intervention or outpatient specialty palliative care clinic (outcomes = quality of life, symptom burden, loneliness, healthcare utilization) Wow! I'm just stunned even writing that! We've come so far as a field. This isn't to say we've “made it” - more to say that we've reached a new stage of maturation of the field - in which the evidence we are discussing is frequently high quality randomized trial level data.  We recorded this on Friday during the annual assembly, and Eric and I were a littttttle off our game due to the residual effects of the GeriPal pub crawl the night before, which were only compounded by technical difficulties.  I believe these issues were more than made up for by our guests' forced accompaniment to the song “Feel Like Making Science.” (Credit to the Beeson singing crew for coming up with that one). Enjoy! -@AlexSmithMD