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2 episodes with chakravarty
2 episodes with chakravarty
2 episodes with chakravarty
2 episodes with chakravarty
2 episodes with chakravarty
2 episodes with chakravarty
6 episodes with chakravarty
2 episodes with chakravarty
In this JCO Article Insights episode, Alexandra Rojek provides a summary on "Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors" by Schaffer et al published in the Journal of Clinical Oncology July 17th, 2024. TRANSCRIPT Alexandra Rojek: Hello and welcome to JCO Article Insights. I'm your host, Alexandra Rojek, and today we will be discussing an original report published in the October 1st issue of JCO titled, “Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors,” by Shaffer et al. The CIBMTR registry study set out to compare outcomes of patients undergoing allogeneic stem cell transplantation hematologic malignancies by HLA antigen matching status as well as by the type of GVHD prophylaxis regimen received either calcineurin inhibitor-based prophylaxis or post-transplant cyclophosphamide or PTCy. This study included patients reported to CIBMTR from January 2017 to June 2021 with AML, ALL or MDS, and required that they have undergone allotransplant with either a calcineurin inhibitor based so tacro or cyclosporine, GVHD prophylaxis, or PTCy, which included a calcineurin inhibitor or sirolimus with or without MMF and ATG. Matched unrelated donors were defined as an 8 out of 8 HLA match. And mismatched unrelated donors were defined as HLA mismatched at any single locus or 7 out of 8. The primary objective of the study aimed to compare overall survival or OS and GVHD and relapse-free survival (GRFS) within and between matched unrelated donors versus mismatched unrelated donors separated by calcineurin inhibitor versus PTCy based GVHD prophylaxis. GRFS was defined as survival without grade 3 to 4 acute GVHD, moderate to severe chronic GVHD requiring systemic therapy or relapse. 10,025 patients were included from 153 centers, with a median follow up of over 36 months. Mismatched unrelated donor recipients were made up of 22% minority ancestry patients as compared to just 8% of patients receiving a matched unrelated donor allo transplant, showing an enrichment for patients of minority ancestry in the mismatched unrelated donor group. Just under 10% of patients were of minority ancestry in the study overall, reflective of challenges in transplant care for these patients, which may include inferior access to care, fewer available and suitably matched donors, among other factors. 54% of all patients were transplanted for AML and 29% for MDS. 45% of patients received myeloablative conditioning, 25% received regimens containing ATG, and 23% overall received PTCy with either a calcineurin inhibitor or sirolimus as well as MMF. Among patients receiving PTCy, the authors did not find differences in overall survival by degree of HLA matching, whereas among patients receiving calcineurin inhibitor-based prophylaxis, there remained survival differences by HLA matching status. When comparing matched unrelated donor calcineurin inhibitor patients with PTCy matched unrelated donor patients, the PTCy arm had better OS, and the mismatched unrelated donor group who received PTCy had similar OS as well. For GRFS, matched unrelated donor and mismatched unrelated donor PTCy patients had no difference in GRFS, similar to the trend the authors see with overall survival. But these patients also had better GRFS than matched unrelated donor patients receiving calcineurin inhibitor-based prophylaxis. Within each prophylaxis arm, there was no difference in GRFS by HLA matching status. HLA mismatched patients receiving PTCy were less likely to experience GRFS than HLA mismatched patients receiving calcineurin inhibitor-based prophylaxis. The authors saw similar differences in comparative trends when subgrouping patients based on conditioning intensity and additionally did not find differences in GRFS and OS by ATG exposure. When looking at patients with minority ancestry, those patients who received a match unrelated donor or mismatched unrelated donor with PTCy had comparable outcomes to non-Hispanic white patients. Additionally, among minority ancestry patients, there was a significant benefit in both GRFS and OS in the PTCy groups as compared to calcineurin inhibitor-based prophylaxis. When examining other specific toxicities included in the composite GRFS endpoint, such as GVHD rates among PTCy patients, the authors note that patients receiving a matched unrelated donor had similar rates of grade 3 to 4 acute GVHD but lower rates of moderate to severe chronic GVHD requiring systemic therapy. There appears to be signal that among PTCy patients, HLA matching reduced rates of moderate to severe chronic GVHD compared to mismatched unrelated donor patients receiving PTCy. These same trends also held when the authors looked at non relapse mortality with no significant differences within the PTCy groups by HLA matching status but reduced non relapse mortality compared to both calcineur and inhibitor-based groups. However, notably, there was a greater risk of relapse among matched unrelated donor PTCy patients than matched unrelated donor calcineurin inhibitor patients, although this risk was comparable between mismatched unrelated donor patients by type of prophylaxis. The authors note that this has also been observed in other retrospective cohorts and may be confounded by differences in conditioning intensity between these cohorts of matched unrelated donor patients, affecting the risk of relapse. Finally, the authors also evaluate whether expansion of donor search criteria to mismatch donors from full HLA matching would increase availability of young donors from minority ancestry patients, and the study noted striking increases for all subgroups examined. This study fits nicely with the BMT CTN 1703 trial published in the recent past, which has showed the superiority of PTCy with the calcineurin inhibitor and MMF when compared with conventional calcineurin inhibitor based immune prophylaxis for reduced intensity matched related donor and matched unrelated donor allotransplant. Of note, very few patients with one HLA antigen mismatch were enrolled on that study. However, others have shown the feasibility of PTCy in the mismatched unrelated donor setting, which has led to its adoption in practice. Although less than a quarter of patients included in this current study received PTCy overall, the findings clearly are aligned with the BMT CTN 1703 study, which is likely to change clinical practice in the longer term in this field. As the accompanying editorial in JCO, written by Dr. Chakravarty nicely lays out, the differences between this study and the EBMT registry study, also published in this issue of JCO are subtle but worthy of note. While both studies show that mismatched unrelated donor patients had worse OS and GRFS than those receiving matched unrelated donor transplants, and then among matched unrelated donor patients the addition of PTCy improved GRFS and OS, there is discordance between the studies whether the addition of PTCy abrogates the effect of HLA mismatching on GRFS and OS. As this editorial points out, there are strikingly different rates of T cell depletion with ATG between the US and Europe, which may account for differences in comparator arms that lead to this discordance. There are several very exciting clinical trials ongoing that will aim to answer some of these outstanding questions regarding comparisons of PTCy and T cell depletion, which the field eagerly looks forward to reviewing. In summary, this registry study of patients receiving allo transplant with matched unrelated donor or mismatched unrelated donor and calcineurin inhibitor or PTCy based GVHD prophylaxis, most notably shows that for patients who may not have a matched unrelated donor available, the addition of PTCy to a mismatched unrelated donor allo transplant allows for improved outcomes after transplant in toxicities and survival. This is most significant for patients of minority ancestries who usually have fewer matched unrelated donors available in registry searches. Improving the transplant options available to these groups of patients is of critical importance in improving equitable access to care for all of our patients. And this study, although retrospective in nature, provides an important understanding of our progress to date and suggests directions for future investigation may indeed be very feasible to continue to close these gaps in care for patients in need of an allo transplant for hematologic malignancies. This is Alexandra Rojek. Thank you for listening to JCO Article Insights. Don't forget to give us a rating or review, and be sure to subscribe so you never miss an episode. You can find all ASCO shows at asco.org/podcasts. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.
Send us a textAuditi Chakravarty is CEO of AERDF (the Advanced Education Research and Development Fund). AERDF applies Advanced Inclusive R&D to find potentially transformative teaching and learning solutions that can scale, centering on the assets, strengths, and needs of Black and Latino learners and all learners experiencing poverty. Auditi also chairs the Board of Bottom Line, a national college access and success organization, and is a venture partner with LearnLaunch Accelerator. A former high school English teacher, Auditi holds a BA in English and M.Ed in Curriculum & Instruction from the University of Illinois at Champaign-Urbana.
Welcome back CTL Squad! Today, we answer your questions on women's health with the incredible OBGYN, Dr. Trina Chakravarty M.D.! Learn all about her profession and life as an OBGYN, as well as, things you can do to live an elevated & healthy lifestyle. A multifaceted, dedicated woman, Dr. Trina Chakravarty, shares her knowledge with us today and answer questions that came in through social media. Thank you all for listening to Catwalk Through Life! I hope you enjoy this episode! *** Elevate your life with gratitude and my Gratitude Journal. Available on Amazon! https://a.co/d/2ufcKL8 Download my FREE Morning Routine Checklist! >> https://catwalkthroughlife.com/2023/06/20/free-30-min-morning-routine-checklist ***** Need a getaway or looking for an upscale Southwestern experience? Book your next stay at Westward Look Wyndham Grand Resort & Spa in Tucson, AZ! You won't be disappointed! Check out Catalina Riding Club while you're there for a one-of-a-kind horseback riding experience! https://www.westwardlook.com | https://catalinariding.net Helpful Links: Dr. Trina Chakravarty Instagram Page: https://www.instagram.com/trinachakra Gratitude Journal: https://a.co/d/2ufcKL8 Catwalk Through Life Blog: https://www.catwalkthroughlife.com Catwalk Through Life Instagram Page: https://www.instagram.com/catwalkthroughlife Catwalk Through Life Facebook Group: https://www.facebook.com/groups/726602181696067 Rashi Stephens-Charlton Instagram Page: https://www.instagram.com/rashistephens Free Morning Routine Checklist for a good morning! Click here: https://catwalkthroughlife.com/2023/06/20/free-30-min-morning-routine-checklist ***** Disclaimer: Please know that any advice given is just a suggestion and what is known to be true in my guest's profession. This is not medical advice for any one person in particular. This is general information. Please consult your doctor for medical questions and use your best judgement on what's best for you. The intent behind this episode is to merely share information and try to help anyone we can! :)
Shameek Chakravarty is the Founder and CEO of Farmizen. Farmizen is a source traceable farm-to-fork marketplace, enabling discovery, transactions, and fulfilment between organic farmers and consumers looking for clean food. In this episode, we talk about "Why should people care about eating Organic Foods", "Why are Organic Fruits Often costly", "Secrets Big Food Companies that control the world don't want you to know about Food", and many more. Interview Breakdown: 1.20 mins - What are organic foods and why should you care about them. 2.10 mins - What is the difference between Organic Foods vs What you get from a general store. 4.07 mins - How do Fruits and Vegetables brought from the general store impact your body and health. 39.57 mins - Who is Shameek and Why should you listen to him? 50.57 mins - Secrets Big Food Companies don't want you to know and are hiding from you. 59.10 mins - How you can reach out to Shameek. Follow us to find daily updates and success hacks on The Growth Mindset Page below: Facebook: https://www.facebook.com/silawathirshad/ Instagram: https://www.instagram.com/silawath_irshad/ Linkedin: https://www.linkedin.com/in/silawathirshad/ Youtube: https://www.youtube.com/c/TheGrowthMindsetwithSilawathIrshad You can find Shameek Chakravarty here: Website: https://www.farmizen.com/ Linkedin: https://www.linkedin.com/in/shameekc/ Twitter: https://twitter.com/shameekc
As summer sweeps in, we find ourselves once again inundated with reports of record-breaking temperatures, unprecedented heat waves, and other climate disasters. As adults, one question to consider is: How do we talk about climate change with young people, who will ultimately inherit this warming planet? And how can we do so in a manner that is not terrifying or depressing, but rather engages and encourages them to care?In this episode, host Sandip Roy speaks with Bijal Vachharajani and Rohan Chakravarty, who regularly grapple with these questions in their work.Bijal is a children's book author, climate warrior and commissioning editor at Pratham Books. And Rohan is a cartoonist, illustrator, wildlife enthusiast, and the creator of Green Humour.Produced by Shashank BhargavaEdited and mixed by Suresh Pawar
Joy Chakravarty is a Dubai-based golf journalist who has worked in golf for nearly 30 years while covering 25+ major championships and Ryder Cups. Joy brings a unique worldly view of the sport while discussing how to grow the game internationally, what might drum up more fan engagement, why more leagues should abandon the Official World Golf Ranking and more. Thanks to our partners: COBRA GOLF: The new COBRA DARKSPEED drivers are the perfect combination of groundbreaking aerodynamics, precision PWR BRIDGE weighting, and AI-designed H.O.T. Face technology that delivers transcendent speed. Learn more at cobragolf.com. Tell your friends about the new show and be sure to follow Claude to submit questions, enter giveaways and keep up with the latest Son of a Butch updates on Instagram at @ClaudeHarmon3. The views and opinions expressed by guests interviewed on the Podcast, including all program participants and guests, are solely their own current opinions regarding events and are based on their own perspective and opinion. The views and opinions expressed do not reflect the views or opinions of Claude Harmon, or the companies with which any program participants/interviewees are, or may be, affiliated.See omnystudio.com/listener for privacy information.
When we talk about public spaces, we often throw around the word 'placemaking' without considering what the term really means. In this conversation, host Eliza Grosvenor is joined by Ruchi Chakravarty (Urban Designer, Masterplanner, Architect and Placemaker) and Federico Ortiz (Head of Content, NLA) to talk all things placemaking, and unpack the meaning of the word. To stay up-to-date with Ruchi's projects, you can follow her on LinkedIn. To keep in the loop with all upcoming NLA events and research, head to the website. You can download the New London Agenda here, and contribute to our Public London research here. To find out more about #LFAat20 or how to get involved in the Festival, head to the LFA website here. Have a question for the podcast? Email info@londonfestivalofarchitecture.org or call 020 7636 4044. This episode was edited and produced by Katya Spiers. You can download the transcript here. Timestamps for this episode: 1:03 Ruchi's relationship with the built environment 2:50 Quick-fire questions 4:20 Unpacking LFA theme 'Reimagine' 5:50 Defining 'placemaking' 11:01 Gillet Square, Dalston 15:30 Meanwhile projects and Harrow Road 18:37 Challenges of placemaking 21:45 Key pillars of placemaking 25:14 The New London Agenda with Federico 27:49 How to use the Agenda and upcoming NLA Research 32:34 Public London 33:57 What does the future of placemaking look like? 37:21 A challenge to LFA organisers 39:53 What would you reimagine?
Welcome to the latest episode of Medmastery's Cardiology Digest, where we keep you up-to-date in the ever-evolving world of cardiology. This episode promises to be a riveting exploration of breakthrough studies! STUDY #1: First, we'll delve into a national registry study on transcatheter mitral valve repair in a population that's different from what the approval was initially based upon. We'll discuss the study's implications, as we eagerly await additional trials comparing this method to traditional surgery. Makkar, RR, Chikwe, J, Chakravarty, T, et al. 2023. Transcatheter mitral valve repair for degenerative mitral regurgitation. JAMA. 20: 1778–1788. (https://doi.org/10.1001/jama.2023.7089) STUDY #2: Next, we turn our attention to a ground-breaking study examining a standardized periprocedural management strategy using direct-acting oral anticoagulants for patients undergoing endoscopy. Given the study's complication rates and length of the anticoagulant interruption period, this novel approach may redefine standards for patients with atrial fibrillation. Hansen-Barkun, C, Martel, M, Douketis, J, et al. 2023. Periprocedural management of patients with atrial fibrillation receiving a direct oral anticoagulant undergoing a digestive endoscopy. Am J Gastroenterol. 5: 812–819. (https://doi.org/10.14309/ajg.0000000000002076) STUDY #3: Our third study puts the spotlight on the challenging mission to enhance the success rate for paroxysmal atrial fibrillation treatment. We'll explore whether wider-area ablation proved superior to standard ablation for reducing recurrence, contrast that to previous trials, and touch on what's most important when considering the reasoning behind the choice of wider-area ablation versus standard ablation. Nair, GM, Birnie, DH, Nery, PB, et al. 2023. Standard vs augmented ablation of paroxysmal atrial fibrillation for reduction of atrial fibrillation recurrence: The AWARE randomized clinical trial. JAMA Cardiol. 5: 475–483. (https://doi.org/10.1001/jamacardio.2023.0212) STUDY #4: Lastly, we dissect a study centered on epicardial ablation for patients with Brugada syndrome who are suffering from ventricular fibrillation. Could this burgeoning therapy eventually replace the current implantable cardioverter–defibrillator approach? Nademanee K et al. Long-term outcomes of Brugada substrate ablation: A report from BRAVO (Brugada Ablation of VF Substrate Ongoing Multicenter Registry). Circulation 2023 Mar 24; [e-pub]. (https://doi.org/10.1161/CIRCULATIONAHA.122.063367) Join us as we unravel the complexities and potential game-changers these studies offer, and embark on a journey to better understand the future landscape of cardiology. Tune in and learn with Medmastery's Cardiology Digest! For show notes, visit us at https://www.medmastery.com/podcasts/cardiology-podcast.
Aloke Chakravarty (https://www.swlaw.com/people/aloke_chakravarty) joins Brian Roberts (https://twitter.com/beeberts) for a compelling discussion about his life and career, including a detailed account of his involvement in the investigation, trial and conviction of the surviving brother responsible for the Boston Marathon bombing. Al shares his personal journey from starting out as a pre-med major at Johns Hopkins University to transitioning to law and attending Emory University School of Law. After beginning his career at a prestigious law firm in Delaware, he made the bold decision to get more trial experience by taking a position in the District Attorney's office in Boston. Al shares that he recalls losing his first dozen cases and questioning his trial strategies, even going so far as to adopt a Boston accent in an attempt to become more persuasive with juries. Al eventually hit his stride and shares several details of his incredible career as a trial attorney working on many high-profile cases, including a behind the scenes look into the successful investigation, trial and conviction of the Boston Marathon bomber. After serving many years as an Assistant United States Attorney at the U.S. Department of Justice in the District of Massachusetts, Al transitioned into private practice where he currently is a Partner at Snell & Wilmer and co-Chair of the firm's investigations, government enforcement and white-collar protection practice group. Al's practice also focuses on matters involving cybersecurity, data protection, data privacy and cryptocurrency.Links:Aloke Chakravarty: https://www.linkedin.com/in/aloke-chakravarty-618753139/Brian Roberts: https://www.linkedin.com/in/brian-roberts-7108497/Snell & Wilmer: https://www.swlaw.comThe Attorney Lounge YouTube: https://www.youtube.com/@TheAttorneyLounge-fd1lo/featuredThe Attorney Lounge Twitter: https://twitter.com/AttorneyLoungeArray: www.trustarray.comArray's Twitter: https://twitter.com/trustarray Lawyers careers
The Bros chat to Joy Chakravarty, review the BMW and ISPS. We add our Tour Championship and European master picks at the end.
In this episode, Peter talks with Mallar Chakravarty about the imminent relaunch of the journal Aperture Neuro, which, a few years ago, was created and supported through OHBM. Here we learn what happened with the first version of Aperture Neuro, what lessons were learned, and what the relaunched version of Aperture offers that is truly unique and valuable to the field. It is non-profit and open access with an APC of 800 dollars for members. It provides an avenue for many different kinds of papers, from typical original research to editorials, tutorials, conference summaries, book reviews, registered reports, and more. It will be heavily weighing the assessment of submitted papers based on their utility and transparency rather than just their novelty. In the future, Aperture Neuro aims to seamlessly support other objects such as code, data, notebooks, and videos, and is currently looking into mechanisms for handling these without compromising on quality or efficiency. For more information about the journal, go to apertureneuro.org Episode producers: Alfie Wearn Stephania Assimopoulos Please send any feedback, guest suggestions, or ideas to ohbm.comcom@gmail.com
“A large chunk of the problems faced in the field today, existed twenty years back,” Prateek Chakravarty, CEO of Zinier. Zinier is a provider of intelligent field service automation solutions that recently announced that it is incorporating ChatGPT, a state-of-the-art large language model (LLM), into its field service solution. This integration will enable Zinier's field workers to access a comprehensive knowledge base in real-time, empowering them to solve technical issues with greater ease and efficiency. In this podcast, Chakravarty ties together his company's work at the leading edge of field service automation, to the realities in the field and to the many people involved. Chakravarty describes the company's focus as making sure frontline workers have access to technology, get to be involved in the digital revolution. Chakravarty discusses “visibility across the chain” on how to make frontline workers more visible. In this short but wide-ranging discussion we encounter things we often don't see when talking about infrastructure, such as equity, safety, empowerment, and more. Chakravarty describes how Zinier helps infrastructure companies make this journey, helping them to see what might be hard to see, and to plan what may have been left out of planning. Visit www.zinier.com
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.26.538263v1?rss=1 Authors: Gaiser, C., van der Vliet, R., de Boer, A. A. A., Donchin, O., Berthet, P., Devenyi, G. A., Chakravarty, M., Diedrichsen, J., Marquand, A. F., Frens, M. A., Muetzel, R. L. Abstract: In the past, the cerebellum has been best known for its crucial role in motor function. However, increasingly more findings highlight the importance of cerebellar contributions in cognitive functions and neurodevelopment. Using large scale, population-wide neuroimaging data, we describe and provide detailed, openly available models of cerebellar development in childhood and adolescence, an important time period for brain development and onset of neuropsychiatric disorders. Next to a traditionally used anatomical parcellation of the cerebellum, we generated growth models based on a recently proposed functional parcellation. In both, we find an anterior-posterior growth gradient mirroring the age-related improvements of underlying behavior and function, which is analogous to cerebral maturation patterns and offers new evidence for directly related cerebello-cortical developmental trajectories. Finally, we illustrate how the current approach can be used to detect cerebellar abnormalities in clinical samples. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Send us a Text Message.For Episode 2 of The Heart Gallery Podcast, I talk to nature's cartoonist, Rohan Chakravarty. Rohan's cartoons about animals, the natural world, and human-environment connections are published as comic strips, books, and educational materials all around the world. He is talented, hilarious, and a critical voice for the voiceless. Listen to be charmed and educated by the inimitable Rohan Chakravarty.Visit The Heart Gallery's visual accompaniment for this podcast episode here (podcast transcript also available here).Rohan's HW: "Just take a look at the nearest tree from your window and make a note of what happens on that tree over one or two hours. Whatever time you can devote. I think that would be the best gateway into nature. I don't think you are going to look back after that."Mentioned:- Genndy Tartakovsky- Gary Larson- Bill Watterson- Rohan's piece on snake clitorises- Rohan's Bird Business- Rohan's Naturalist RuddyConnect:- Green Humour website - Green Humour IG- The Heart Gallery Instagram- The Heart Gallery website- Rebeka Ryvola de Kremer InstagramCredits:Samuel Cunningham for podcast editing, Cosmo Sheldrake for use of his song Pelicans We, podcast art by me, Rebeka Ryvola de Kremer.
In Fictions of Consent: Slavery, Servitude, and Free Service in Early Modern England (U Pennsylvania Press, 2022), Urvashi Chakravarty excavates the ideologies of slavery that took root in early modern England in the period that preceded the development of an organized trade in enslaved persons. Despite the persistent fiction that England was innocent of racialized slavery, Chakravarty argues that we must hold early modern England—and its narratives of exceptional and essential freedom—to account for the frameworks of slavery that it paradoxically but strategically engendered. Slavery was not a foreign or faraway phenomenon, she demonstrates; rather, the ideologies of slavery were seeded in the quotidian spaces of English life and in the everyday contexts of England's service society, from the family to the household, in the theater and, especially, the grammar school classroom, where the legacies of classical slavery and race were inherited and negotiated. The English conscripted the Roman freedman's figurative "stain of slavery" to register an immutable sign of bondage and to secure slavery to epidermal difference, even as early modern frameworks of "volitional service" provided the strategies for later fictions of "happy slavery" in the Atlantic world. Early modern texts presage the heritability of slavery in early America, reveal the embeddedness of slavery within the family, and illuminate the ways in which bloodlines of descent underwrite the racialized futures of enslavement. Fictions of Consent intervenes in a number of areas including early modern literary and cultural studies, premodern critical race studies, the reception of classical antiquity, and the histories of law, education, and labor to uncover the conceptual genealogies of slavery and servitude and to reveal the everyday sites where the foundations of racialized slavery were laid. Although early modern England claimed to have "too pure an Air for Slaves to breathe in," Chakravarty reveals slavery was a quintessentially English phenomenon. Urvashi Chakravarty is Associate Professor of English at the University of Toronto and works on early modern English literature, critical race studies, queer studies, and the history of slavery, Alexandra Ortolja-Baird is Lecturer in Digital History and Culture at the University of Portsmouth. She tweets at @timetravelallie. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
In Fictions of Consent: Slavery, Servitude, and Free Service in Early Modern England (U Pennsylvania Press, 2022), Urvashi Chakravarty excavates the ideologies of slavery that took root in early modern England in the period that preceded the development of an organized trade in enslaved persons. Despite the persistent fiction that England was innocent of racialized slavery, Chakravarty argues that we must hold early modern England—and its narratives of exceptional and essential freedom—to account for the frameworks of slavery that it paradoxically but strategically engendered. Slavery was not a foreign or faraway phenomenon, she demonstrates; rather, the ideologies of slavery were seeded in the quotidian spaces of English life and in the everyday contexts of England's service society, from the family to the household, in the theater and, especially, the grammar school classroom, where the legacies of classical slavery and race were inherited and negotiated. The English conscripted the Roman freedman's figurative "stain of slavery" to register an immutable sign of bondage and to secure slavery to epidermal difference, even as early modern frameworks of "volitional service" provided the strategies for later fictions of "happy slavery" in the Atlantic world. Early modern texts presage the heritability of slavery in early America, reveal the embeddedness of slavery within the family, and illuminate the ways in which bloodlines of descent underwrite the racialized futures of enslavement. Fictions of Consent intervenes in a number of areas including early modern literary and cultural studies, premodern critical race studies, the reception of classical antiquity, and the histories of law, education, and labor to uncover the conceptual genealogies of slavery and servitude and to reveal the everyday sites where the foundations of racialized slavery were laid. Although early modern England claimed to have "too pure an Air for Slaves to breathe in," Chakravarty reveals slavery was a quintessentially English phenomenon. Urvashi Chakravarty is Associate Professor of English at the University of Toronto and works on early modern English literature, critical race studies, queer studies, and the history of slavery, Alexandra Ortolja-Baird is Lecturer in Digital History and Culture at the University of Portsmouth. She tweets at @timetravelallie. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/history
In Fictions of Consent: Slavery, Servitude, and Free Service in Early Modern England (U Pennsylvania Press, 2022), Urvashi Chakravarty excavates the ideologies of slavery that took root in early modern England in the period that preceded the development of an organized trade in enslaved persons. Despite the persistent fiction that England was innocent of racialized slavery, Chakravarty argues that we must hold early modern England—and its narratives of exceptional and essential freedom—to account for the frameworks of slavery that it paradoxically but strategically engendered. Slavery was not a foreign or faraway phenomenon, she demonstrates; rather, the ideologies of slavery were seeded in the quotidian spaces of English life and in the everyday contexts of England's service society, from the family to the household, in the theater and, especially, the grammar school classroom, where the legacies of classical slavery and race were inherited and negotiated. The English conscripted the Roman freedman's figurative "stain of slavery" to register an immutable sign of bondage and to secure slavery to epidermal difference, even as early modern frameworks of "volitional service" provided the strategies for later fictions of "happy slavery" in the Atlantic world. Early modern texts presage the heritability of slavery in early America, reveal the embeddedness of slavery within the family, and illuminate the ways in which bloodlines of descent underwrite the racialized futures of enslavement. Fictions of Consent intervenes in a number of areas including early modern literary and cultural studies, premodern critical race studies, the reception of classical antiquity, and the histories of law, education, and labor to uncover the conceptual genealogies of slavery and servitude and to reveal the everyday sites where the foundations of racialized slavery were laid. Although early modern England claimed to have "too pure an Air for Slaves to breathe in," Chakravarty reveals slavery was a quintessentially English phenomenon. Urvashi Chakravarty is Associate Professor of English at the University of Toronto and works on early modern English literature, critical race studies, queer studies, and the history of slavery, Alexandra Ortolja-Baird is Lecturer in Digital History and Culture at the University of Portsmouth. She tweets at @timetravelallie. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/literary-studies
In Fictions of Consent: Slavery, Servitude, and Free Service in Early Modern England (U Pennsylvania Press, 2022), Urvashi Chakravarty excavates the ideologies of slavery that took root in early modern England in the period that preceded the development of an organized trade in enslaved persons. Despite the persistent fiction that England was innocent of racialized slavery, Chakravarty argues that we must hold early modern England—and its narratives of exceptional and essential freedom—to account for the frameworks of slavery that it paradoxically but strategically engendered. Slavery was not a foreign or faraway phenomenon, she demonstrates; rather, the ideologies of slavery were seeded in the quotidian spaces of English life and in the everyday contexts of England's service society, from the family to the household, in the theater and, especially, the grammar school classroom, where the legacies of classical slavery and race were inherited and negotiated. The English conscripted the Roman freedman's figurative "stain of slavery" to register an immutable sign of bondage and to secure slavery to epidermal difference, even as early modern frameworks of "volitional service" provided the strategies for later fictions of "happy slavery" in the Atlantic world. Early modern texts presage the heritability of slavery in early America, reveal the embeddedness of slavery within the family, and illuminate the ways in which bloodlines of descent underwrite the racialized futures of enslavement. Fictions of Consent intervenes in a number of areas including early modern literary and cultural studies, premodern critical race studies, the reception of classical antiquity, and the histories of law, education, and labor to uncover the conceptual genealogies of slavery and servitude and to reveal the everyday sites where the foundations of racialized slavery were laid. Although early modern England claimed to have "too pure an Air for Slaves to breathe in," Chakravarty reveals slavery was a quintessentially English phenomenon. Urvashi Chakravarty is Associate Professor of English at the University of Toronto and works on early modern English literature, critical race studies, queer studies, and the history of slavery, Alexandra Ortolja-Baird is Lecturer in Digital History and Culture at the University of Portsmouth. She tweets at @timetravelallie. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/intellectual-history
In Fictions of Consent: Slavery, Servitude, and Free Service in Early Modern England (U Pennsylvania Press, 2022), Urvashi Chakravarty excavates the ideologies of slavery that took root in early modern England in the period that preceded the development of an organized trade in enslaved persons. Despite the persistent fiction that England was innocent of racialized slavery, Chakravarty argues that we must hold early modern England—and its narratives of exceptional and essential freedom—to account for the frameworks of slavery that it paradoxically but strategically engendered. Slavery was not a foreign or faraway phenomenon, she demonstrates; rather, the ideologies of slavery were seeded in the quotidian spaces of English life and in the everyday contexts of England's service society, from the family to the household, in the theater and, especially, the grammar school classroom, where the legacies of classical slavery and race were inherited and negotiated. The English conscripted the Roman freedman's figurative "stain of slavery" to register an immutable sign of bondage and to secure slavery to epidermal difference, even as early modern frameworks of "volitional service" provided the strategies for later fictions of "happy slavery" in the Atlantic world. Early modern texts presage the heritability of slavery in early America, reveal the embeddedness of slavery within the family, and illuminate the ways in which bloodlines of descent underwrite the racialized futures of enslavement. Fictions of Consent intervenes in a number of areas including early modern literary and cultural studies, premodern critical race studies, the reception of classical antiquity, and the histories of law, education, and labor to uncover the conceptual genealogies of slavery and servitude and to reveal the everyday sites where the foundations of racialized slavery were laid. Although early modern England claimed to have "too pure an Air for Slaves to breathe in," Chakravarty reveals slavery was a quintessentially English phenomenon. Urvashi Chakravarty is Associate Professor of English at the University of Toronto and works on early modern English literature, critical race studies, queer studies, and the history of slavery, Alexandra Ortolja-Baird is Lecturer in Digital History and Culture at the University of Portsmouth. She tweets at @timetravelallie. Learn more about your ad choices. Visit megaphone.fm/adchoices
In Fictions of Consent: Slavery, Servitude, and Free Service in Early Modern England (U Pennsylvania Press, 2022), Urvashi Chakravarty excavates the ideologies of slavery that took root in early modern England in the period that preceded the development of an organized trade in enslaved persons. Despite the persistent fiction that England was innocent of racialized slavery, Chakravarty argues that we must hold early modern England—and its narratives of exceptional and essential freedom—to account for the frameworks of slavery that it paradoxically but strategically engendered. Slavery was not a foreign or faraway phenomenon, she demonstrates; rather, the ideologies of slavery were seeded in the quotidian spaces of English life and in the everyday contexts of England's service society, from the family to the household, in the theater and, especially, the grammar school classroom, where the legacies of classical slavery and race were inherited and negotiated. The English conscripted the Roman freedman's figurative "stain of slavery" to register an immutable sign of bondage and to secure slavery to epidermal difference, even as early modern frameworks of "volitional service" provided the strategies for later fictions of "happy slavery" in the Atlantic world. Early modern texts presage the heritability of slavery in early America, reveal the embeddedness of slavery within the family, and illuminate the ways in which bloodlines of descent underwrite the racialized futures of enslavement. Fictions of Consent intervenes in a number of areas including early modern literary and cultural studies, premodern critical race studies, the reception of classical antiquity, and the histories of law, education, and labor to uncover the conceptual genealogies of slavery and servitude and to reveal the everyday sites where the foundations of racialized slavery were laid. Although early modern England claimed to have "too pure an Air for Slaves to breathe in," Chakravarty reveals slavery was a quintessentially English phenomenon. Urvashi Chakravarty is Associate Professor of English at the University of Toronto and works on early modern English literature, critical race studies, queer studies, and the history of slavery, Alexandra Ortolja-Baird is Lecturer in Digital History and Culture at the University of Portsmouth. She tweets at @timetravelallie. Learn more about your ad choices. Visit megaphone.fm/adchoices
In Fictions of Consent: Slavery, Servitude, and Free Service in Early Modern England (U Pennsylvania Press, 2022), Urvashi Chakravarty excavates the ideologies of slavery that took root in early modern England in the period that preceded the development of an organized trade in enslaved persons. Despite the persistent fiction that England was innocent of racialized slavery, Chakravarty argues that we must hold early modern England—and its narratives of exceptional and essential freedom—to account for the frameworks of slavery that it paradoxically but strategically engendered. Slavery was not a foreign or faraway phenomenon, she demonstrates; rather, the ideologies of slavery were seeded in the quotidian spaces of English life and in the everyday contexts of England's service society, from the family to the household, in the theater and, especially, the grammar school classroom, where the legacies of classical slavery and race were inherited and negotiated. The English conscripted the Roman freedman's figurative "stain of slavery" to register an immutable sign of bondage and to secure slavery to epidermal difference, even as early modern frameworks of "volitional service" provided the strategies for later fictions of "happy slavery" in the Atlantic world. Early modern texts presage the heritability of slavery in early America, reveal the embeddedness of slavery within the family, and illuminate the ways in which bloodlines of descent underwrite the racialized futures of enslavement. Fictions of Consent intervenes in a number of areas including early modern literary and cultural studies, premodern critical race studies, the reception of classical antiquity, and the histories of law, education, and labor to uncover the conceptual genealogies of slavery and servitude and to reveal the everyday sites where the foundations of racialized slavery were laid. Although early modern England claimed to have "too pure an Air for Slaves to breathe in," Chakravarty reveals slavery was a quintessentially English phenomenon. Urvashi Chakravarty is Associate Professor of English at the University of Toronto and works on early modern English literature, critical race studies, queer studies, and the history of slavery, Alexandra Ortolja-Baird is Lecturer in Digital History and Culture at the University of Portsmouth. She tweets at @timetravelallie. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/european-studies
In Fictions of Consent: Slavery, Servitude, and Free Service in Early Modern England (U Pennsylvania Press, 2022), Urvashi Chakravarty excavates the ideologies of slavery that took root in early modern England in the period that preceded the development of an organized trade in enslaved persons. Despite the persistent fiction that England was innocent of racialized slavery, Chakravarty argues that we must hold early modern England—and its narratives of exceptional and essential freedom—to account for the frameworks of slavery that it paradoxically but strategically engendered. Slavery was not a foreign or faraway phenomenon, she demonstrates; rather, the ideologies of slavery were seeded in the quotidian spaces of English life and in the everyday contexts of England's service society, from the family to the household, in the theater and, especially, the grammar school classroom, where the legacies of classical slavery and race were inherited and negotiated. The English conscripted the Roman freedman's figurative "stain of slavery" to register an immutable sign of bondage and to secure slavery to epidermal difference, even as early modern frameworks of "volitional service" provided the strategies for later fictions of "happy slavery" in the Atlantic world. Early modern texts presage the heritability of slavery in early America, reveal the embeddedness of slavery within the family, and illuminate the ways in which bloodlines of descent underwrite the racialized futures of enslavement. Fictions of Consent intervenes in a number of areas including early modern literary and cultural studies, premodern critical race studies, the reception of classical antiquity, and the histories of law, education, and labor to uncover the conceptual genealogies of slavery and servitude and to reveal the everyday sites where the foundations of racialized slavery were laid. Although early modern England claimed to have "too pure an Air for Slaves to breathe in," Chakravarty reveals slavery was a quintessentially English phenomenon. Urvashi Chakravarty is Associate Professor of English at the University of Toronto and works on early modern English literature, critical race studies, queer studies, and the history of slavery, Alexandra Ortolja-Baird is Lecturer in Digital History and Culture at the University of Portsmouth. She tweets at @timetravelallie. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/british-studies
Dr. Anupam Chakravarty is a researcher whose research interests have straddled the disciplines of biochemistry and genomics with a keen focus on the biology of cancer. Currently, he is a senior scientist developing liquid biopsy assays and products in the precision oncology space at Guardant Health. Prior to joining Guardant Health, he ran his own lab as an Assistant Professor at the University of Michigan Ann Arbor. He obtained his Ph.D. from Memorial Sloan Kettering in New York City and was a Damon Runyon Cancer Research Foundation fellow at Stanford University. Anupam is motivated by a strong sense of community building and being deeply invested in the graduate education landscape. He is building and managing a global community of graduate students - GradGrid on Linkedin. He lives in the Bay area with his wife and a cat, enjoys the outdoors, and has a strong academic interest in learning about the world through the lens of postage stamps. In this episode, we discuss the nuances of leaving a professorship to pursue industry research, the landscape of careers in graduate education, and the benefits of being a part of the GradGrid community.Hosted by Joe Varriale.
Episode 62. Anupam Chakravarty is a Senior Scientist at Guardant Health. After doing a postdoc at Stanford, Anupam spent time as an Assistant Professor at the University of Michigan. Anupam completed his PhD from Cornell University and did his dissertation research at Memorial Sloan Kettering Cancer Center.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.18.512730v1?rss=1 Authors: Costantino, M., Pigeau, G., Parent, O., Ziolkowski, J., Devenyi, G. A., Gervais, N. J., Chakravarty, M. M. Abstract: The menopause transition has been repeatedly associated with decreased cognitive performance and increased incidence of Alzheimer's Disease (AD), particularly when it is induced surgically 1,2 or takes place at a younger age 3,4. However, there are very few studies that use neuroimaging techniques to examine the effects of these variables in aggregate and in a large sample. Here, we use data from thousands of participants from the UK Biobank to assess the relationship between menopausal status, menopause type (surgical or natural), and age at menopause with cogniton, AD, and neuroanatomical measures derived from magnetic resonance imaging. We find that for brain and cognitive measures, menopausal status, menopause type and age at surgical menopause do not impact the brain; but that there is a positive correlation between anatomy, cognition and age at non-surgical menopause. These results do not align with previous reports in the literature with smaller samples. However, we confirm that both early and surgical menopause are associated with a higher risk of developing AD, indicating that early and abrupt ovarian hormone deprivation might contribute to the development of the disorder. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
I am quoting our today's guest's from one of his article…“I have this presentation that starts with me asking my viewers to identify three sets of entities that are put forth visually: The first set of people is Priyanka Chopra and Nick Jonas, the second set is Narendra Modi and Donald Trump and the third is a species of Dragonfly which is very common in India called Ground Skimmer. And most people, unless you are scientists, can identify the first two sets of entities but not the third one. And that is my main complaint because my life and the lives of my viewers revolve more around the dragonfly, rather than Priyanka Chopra, or Narendra Modi, as the dragonfly eats mosquitoes and saves us from diseases.“Today after a year long chase finally we have Rohan Chakravarty with us on Audiogyan. He frankly needs no introduction. Rohan is a cartoonist, illustrator, wildlife buff and creator of Green Humour, a series of comic strips about nature. He tweets as @thetoonguy and posts as @green_humour on Instagram.People around me and including myself can identify cars but not trees or birds. How did you get into this and what keeps you so motivated to go in depths of each artwork on various levels… technically, politically, artistically and more…?What is the difference between a comic, a cartoon and an illustration? How do you capture and then curate the core essence of what you wish to communicate. For eg: I am not much into wildlife but became your fan when i saw your Abbas Kiarostami comic.Where does the humour come from? How would you define your style of work? Why do critics who think of anthropomorphism as a weakness in a storyteller's inventory?How do you find balance between the artistic side of your work and the scientific side? How has it changed over time? Is the political narrative increasing as each passing day with situation around us?What is the toughest part of your job? What 3 things you would suggest artists, designers, problem solvers, if they want to be like you?Reference readinghttps://indianwritinginenglish.uohyd.ac.in/on-the-conservation-trail-with-rohan-chakravarty-an-interview/https://twitter.com/thetoonguy?lang=enhttps://www.instagram.com/green_humour/?hl=enhttps://www.greenhumour.comhttps://eco-spotlight.com/spotlight-interview/green-cartoonist-rohan-chakravarty/https://www.thenewsminute.com/article/too-many-issues-too-little-time-author-rohan-chakravarty-green-humour-152608https://www.wildnavigator.com/2012/06/a-cartoonist-draws-wildlife-conservation-meet-rohan-chakravarty/
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.12.511820v1?rss=1 Authors: Tullo, S., Miranda, A. S., del Cid-Pellitero, E., Peng Lim, M., Gallino, D., Attaran, A., Patel, R., Novikov, V., Park, M., Beraldo, F., Luo, W., Shlaifer, I., Durcan, T. M., Bussey, T. J., Saksida, L. M., Fon, E. A., Prado, V. F., Prado, M. A. M., Chakravarty, M. M. Abstract: There is significant evidence suggesting aggregated misfolded alpha-synuclein, a major component of Lewy bodies, propagates in a prion-like manner contributing to disease progression in Parkinson's disease (PD) and other synucleinopathies. Animal models are essential for understanding and developing treatments for these diseases. However, despite modelling human pathology, most endpoints studied in mice do not translate to humans. Furthermore, the progression by which alpha-synuclein misfolding affects human-relevant measures such as brain volume and underlying subtle, high-level cognitive deficits is poorly understood. Here we used a mouse model of synucleinopathy; hemizygous M83 human A53T alpha-synuclein transgenic mice inoculated with recombinant human alpha-synuclein preformed fibrils (PFF) injected in the right striatum to initiate alpha-synuclein misfolding and aggregation. We examined alpha-synuclein-induced atrophy at 90 days post-injection using ex vivo magnetic resonance imaging as well as high-level cognition and motor function, as biomarkers of alpha-synuclein toxicity. We observed widespread atrophy in bilateral regions that project to or receive input from the injection site, highlighting a network of regions that are consistent with structural changes observed in humans with PD. Moreover, we detected early deficits in reversal learning with touchscreen testing in PFF-injected mice prior to motor dysfunction, consistent with the pathology observed in cortical-striatal and thalamic loops. We show, using translational approaches in mice, that progression of prion-like spreading of alpha-synuclein causes selective atrophy via connected brain regions leading to high-level cognitive deficits. We propose that precise imaging and cognitive biomarkers can provide a more direct and human-relevant measurement of alpha-synuclein-induced toxicity in pre-clinical testing. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Payal Chakravarty, Head of Product for Security and Risk from Coalition, sits down to share her story of working at several different organizations, including interning for IBM and Microsoft. After obtaining her master's degree, she worked with IBM a bit more closely and fell in love with one of the projects she was working on. Payal had a very interesting career path going from physical to virtual, virtual to cloud now, cloud to containers. She says that there is still some bias she has dealt with as a woman in her field, she says, "I think the way you handle it is you negotiate or you kind of calmly handle the situation, there's no ego involved." Payal shares that in working in this field you need to be in love with it, giving the advice that don't just choose a job because of the money or because it's cool, but because you feel connected to it as a profession. We thank Payal for sharing her story.
Payal Chakravarty, Head of Product for Security and Risk from Coalition, sits down to share her story of working at several different organizations, including interning for IBM and Microsoft. After obtaining her master's degree, she worked with IBM a bit more closely and fell in love with one of the projects she was working on. Payal had a very interesting career path going from physical to virtual, virtual to cloud now, cloud to containers. She says that there is still some bias she has dealt with as a woman in her field, she says, "I think the way you handle it is you negotiate or you kind of calmly handle the situation, there's no ego involved." Payal shares that in working in this field you need to be in love with it, giving the advice that don't just choose a job because of the money or because it's cool, but because you feel connected to it as a profession. We thank Payal for sharing her story.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.09.09.506402v1?rss=1 Authors: Valiquette, V., Guma, E., Cupo, L., Gallino, D., Anastassiadis, C., Snook, E., Devenyi, G. A., Chakravarty, M. M. Abstract: Our current understanding of litter variability in neurodevelopmental studies using mouse may limit translation of neuroscientific findings. Higher variance of measures across litters than within, often termed intra-litter likeness, may be attributable to pre- and postnatal environment. This study aimed to assess the litter-effect within behavioral assessments (2 timepoints), and anatomy using T1-weighted magnetic resonance images (4 timepoints) across 72 brain region volumes (36 C57bl/6J inbred mice; 7 litters: 19F/17M). Between-litter comparisons of brain and behavioral measures and their associations were evaluated using univariate and multivariate techniques. A power analysis using simulation methods was then performed modeling neurodevelopment and evaluating trade-offs between number-of-litters, mice-per-litter, and sample size. Our results show litter-specific developmental effects, from the adolescent period to adulthood for brain structure volumes and behaviors, and their associations in adulthood. Our power simulation analysis results suggest increasing the number-of-litters in experimental design to achieve the smallest total sample size for detecting different rates of change in specific brain regions. Our results also demonstrate how litter-specific effects may influence development and that increasing the litters to the total sample size ratio should be strongly considered when designing neurodevelopmental studies. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer
Flora interviews Delhi-based architect, urban designer and educator Tapan Chakravarty, to find out more about building with true community impact. Tapan describes how traditional, vernacular housing in rural India mirrors the characteristics of the local environment, climate and natural materials – and how the lifestyle of villagers and their ways of using domestic spaces have been culturally inherited over many generations. Amongst other themes, Flora and Tapan explore how being curious about the past is key to understanding the built environment of today – this is a mindset that Tapan encourages in his students at the Pearl Academy's School of Design in Delhi.
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This episode is alive session from Jaipur Lit Fest 2022. "Shantiniketan": Radha Chakravarty and Reba Som in conversation.
Leaders of B2B - Interviews on B2B Leadership, Tech, SaaS, Revenue, Sales, Marketing and Growth
Prateek Chakravarty, CEO at Zinier, provides a fresh perspective for SaaS startups in this episode. His vision focuses on the https://www.zinier.com/deskless worker. This sector is often overlooked when it comes to software. It includes workers in the field and trades that power our world.Chakravarty experienced the business problems of the deskless worker when working on isolated oil rigs for months on end. Challenges included having to submit status reports, requests for parts and supplies, and organizing schedules. He feels that software companies have focused too much on the back office but not directly on the deskless workers.Chakravarty believes these problems have caused a decline in this sector. Younger people no longer find this sector appealing and are opting for white-collar roles. He believes that this disparity will cause problems in the future. Deskless worker costs will be driven up, the quality of their output may decline, and it will affect every commodity on the planet.Chakravarty insists that a great software product is one that revolves around its user. This is why it's essential for every developer to be immersed in the experience of the deskless worker. Details like the software being able to work when the user is wearing thick gloves or in locations with extreme noise must be factored in. Startup founders and business leaders looking for inspiration and innovation will find Chakravarty's vision insightful. His approach to the user experience can enhance any product-focused business leader. Website - zinier.comLinkedIn - https://www.linkedin.com/in/prateekchakravarty/This episode is brought to you by Content Allies.Content Allies helps B2B tech companies launch revenue-generating podcasts. Build relationships that drive revenue through podcast networking. We schedule interviews with your ideal prospects and strategic partners so that you can build relationships & grow your business. You show up and have conversations, we handle everything else. Learn more at ContentAllies.com
A mammal that can fly. Like proper flap-flap bird-fly. Bats are unicorn-level phantasmal creatures with Greek god fitness levels, living amongst us! This episode is dedicated to these marvellous, under-appreciated creatures and is a full blown effort to take on the undeserving bad raps that bats have. Dispelling myths, addressing batty Covid fears, getting into the true meaning of the term ‘batshit crazy' and giving us logical, scientific suggestions to live considerate lives, making room for bats is a near impossible task. So we called the best man for the job - bat biologist Rohit Chakravarty who has worked with 100s of bats over the last 9 years. This episode also features Zareef Khan, a Van Gujjar from Uttarakhand and Rohit's field assistant. He gives us incredible field stories on bats and banshees and keeps it real and relatable for regular (not-a-scientist) folks like you and me. Show notesFollow Rohit: @paintedbatFollow the show : @tigressontuktuk For Information on MAEEhttps://india.mongabay.com/2021/05/van-gujjars-people-of-the-forest-or-nowhere/https://www.earthtouchnews.com/natural-world/animal-behaviour/watch-falling-sex-bats-give-us-a-glimpse-into-the-weird-world-of-bat-mating/https://www.nytimes.com/2020/12/11/opinion/covid-bats.html
On this month's episode, Soumya D. Chakravarty, MD, PhD, discusses the growing body of clinical evidence evaluating joint efficacy, safety and patient-reported outcomes in patients with psoriatic arthritis receiving guselkumab.
On this month's episode, I spoke with Soumya D. Chakravarty, MD, PhD, to discuss the growing body of clinical evidence evaluating joint efficacy, safety and patient-reported outcomes in patients with psoriatic arthritis receiving guselkumab. Time Stamps: 0:50: Can you tell me more about guselkumab and how it is used to treat patients with psoriatic arthritis? 3:32: What were the study designs and methods used in developing the DISCOVER-1 and DISCOVER-2 trials? 5:43: What were the primary (and any secondary) endpoints evaluated in these trials? 7:00: What were the results regarding efficacy, safety, and patient-reported outcomes that were presented at the ACR? 9:23: What does this clinical research mean for both rheumatologists and their patients? 12:07: Is there anything else you'd like our audience to know about guselkumab or Janssen before we wrap up?
Content Warning: Domestic Abuse This week AJ Langley speaks to Subhasree Chakravarty about the mathematic and mystic Khona. We discuss her sayings, poetic couplets, and advice for all areas of rural life. We also discuss disguising mathematical brilliance as mystical inspiration and calling out your father-in-law for being bad at his job. Follow us on Twitter @myfavmystic, and if you are enjoying the podcast, rate and review us on your podcast app of choice!
Cartooning, Environmental Conservation (and More Wild Things) with Rohan Chakravarty | Baatein LIVE About the guest: Rohan Chakravarty is a cartoonist, illustrator, wildlife enthusiast and the creator of Green Humour- a series of comics on wild animals and nature conservation. Cartoons and illustrations from Green Humour have appeared in Sanctuary Asia, Tinkle Digest, and the National Geographic Traveller. In this episode of Baatein LIVE, we spoke about his process of research, collaborating with scientists, how to incorporate humour into sensitive themes, and the side effects (including trolling) that come with having a public platform. Follow @green_humour : https://instagram.com/green_humour?utm_medium=copy_link Hosted by Vaishnavi Laddha @vaishnai.laddha : https://instagram.com/vaishnavi.laddha?utm_medium=copy_link Presented by Baatein: Baatein, which translates to ‘a conversation', is the National Institute of Design's unique interactive platform to learn and share. From telling us about your experiences and passions to showcasing what you do, it can be anything you want it to be! All links available: https://linktr.ee/baatein.nid Follow us on Instagram: @baatein.nid: https://www.instagram.com/baatein.nid/ Subscribe to our Youtube Channel: https://youtube.com/c/BaateinNID Follow us on LinkedIn: https://www.linkedin.com/company/baatein-nid
As of November 2021, more than 46.4 million people in the UK have received at least one dose of the COVID-19 vaccine as part of the biggest mass-immunization programme the country has ever run. Most of us rushed to book our appointments as soon as we received a message, keen to protect ourselves from the virus. However, not everyone has been quite so confident in the vaccine. In this episode, Jasmine Chakravarty speaks to four UCL academics to learn more about vaccine hesitancy and the evolution of public messaging. She wants to know: what it is, which groups are hesitant and why, and how this hesitancy can best be approached Listen to leading researchers from the Department of Science and Technology Studies (STS) and other UCL departments who talk about hesitancy as a process and who try to better understand how engagement around this topic should work. Jasmine would like to thank her fantastic guests Professor Helen Bedford @HelenEBedford, Dr Stephen Hughes @stephenhues, Dr Katherine Woolf, and Professor Sarah Edwards. For more information on vaccine hesitancy visit: https://www.ecdc.europa.eu/en/immunisation-vaccines/vaccine-hesitancy For more advice on how to talk to those who are hesitant, see: https://www.technologyreview.com/2021/08/16/1032001/how-to-talk-to-unvaccinated-people To read Dr Katherine Woolf's research paper ‘Dispel myths and build trust to combat vaccine hesitancy among ethnic minority health workers', follow the link: https://www.sciencedirect.com/science/article/pii/S2666776221001575?via%3Dihub Find out more about vaccine hesitancy among ethnic minority groups in the UK: https://www.reuters.com/article/us-health-coronavirus-britain-vaccines-f-%20idUSKBN2A925Q https://www.bmj.com/content/372/bmj.n513 To learn more about the ‘COVID-19 Wellbeing Study' with which Professor Sarah Edwards is involved, follow: https://bmjopen.bmj.com/content/11/1/e043418.long For more information about UCL's Master's in Science Communication (MSc) https://ucl.ac.uk/sts/msc We also mentioned our annual newsletter, STS Alchemy. For your free copy, visit: https://ucl.ac.uk/sts/alchemy Featuring Interviewer and episode creator: Jasmine Chakravarty (UCL 2021) Host: Professor Joe Cain, Professor in History and Philosophy of Biology Music credits “Rollin At 5,” by Kevin MacLeod https://filmmusic.io/song/5000-rollin-at-5 “Sweeter Vermouth,” by Kevin MacLeod https://filmmusic.io/song/4450-sweeter-vermouth License: http://creativecommons.org/licenses/by/4.0/ Production information Jasmine edited and produced the main segments of this episode. The balance of editing and post-production by Professor Joe Cain. Podcast information “WeAreSTS” is a production of the Department of Science and Technology Studies (STS) at University College London (UCL). To find out more, and to leave feedback about the show, visit us online: https://www.ucl.ac.uk/sts/podcast STS Students and staff also can find on the website information about how to get involved with our programme. WeAreSTS producer is Professor Joe Cain. Twitter: @stsucl #WeAreSTS
Soumya Chakravarty, MD, PhD, discusses the unmet patient needs in immune-mediated diseases as well as Janssen's work in scientific innovation that allows patients to live their lives more unburdened by their disease. Chakravarty is the Sr Director and Strategic Lead in the Rheumatology Therapeutics area at Janssen.
Soumya Chakravarty, MD, PhD, discusses the unmet patient needs in immune-mediated diseases as well as Janssen's work in scientific innovation that allows patients to live their lives more unburdened by their disease. Chakravarty is the Sr Director and Strategic Lead in the Rheumatology Therapeutics area at Janssen. Time stamps: 0:45: Why do you believe fewer than 10% of patients achieve sustained clinical remission? 3:36: What are some of the unmet needs in immune-mediated diseases? 5:41: Are there any conditions that are especially suffering from this? 9:44: What are some of the scientific and experience innovations that Janssen utilizes to help drive treatment advancement? 12:21: How does Janssen focus on where the impact of disease on patients where it is highest and gaps in treatment are greatest? 16:38: How do you believe we can achieve greater numbers of patients in remission? 20:29: Can you tell me a bit about how collaboration helps patients navigate their own treatment journey? 22:38: Is there anything else you'd like our audience to know?
Song Bilot tirebirai_By Ragini Chakravarty. Ly Kamalananda Bhattacharyya
Welcome to Episode 3 of the Imperfect Swing Golf Podcast :) On the podcast today we have Joy Chakravarty, one of the most recognised names in Sports Journalism! Joy shares his thoughts on journalism, influencers and social media in the golfing world. Follow Joy here: https://www.instagram.com/thejoyofgolf https://twitter.com/thejoyofgolf Follow us and let us know what you think about the episode! www.instagram.com/imperfectswing www.facebook.com/imperfectswing www.twitter.com/imperfectswing Thanks for listening! Catch you at the next one!
Recorded at Digital Sound Studio, Delhi, 2002 Music: Dr Saubhaguavardhan Ghazal: Kantimohan 'Soz' --- Send in a voice message: https://podcasters.spotify.com/pod/show/sm-irfan/message
Recorded at Digital Sound Studio, Delhi, 2002 Music: Dr Saubhaguavardhan Ghazal: Kantimohan 'Soz' --- Send in a voice message: https://podcasters.spotify.com/pod/show/sm-irfan/message
Hemantha is a student at Harvard, who is currently working at the Bill and Melinda Gates Foundation. He has worked with the India CEA and the RBI. We talk about What makes certain government schemes successful? Does being a debater make you more adversarial? How would he change RCTs? --- Send in a voice message: https://anchor.fm/pradyumna-sp/message
Versatility Of Indian Music As Therapeutic Implement | Ruma Chakravarty | Musicology | #SangamTalks SrijanTalks
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.22.393074v1?rss=1 Authors: Roy, N., Kabir, A. H., Zahan, N., Mouna, S. T., Chakravarty, S., Rahman, A. H., Bayzid, M. S. Abstract: Rice genetic diversity is regulated by multiple genes and is largely dependent on various environmental factors. Uncovering the genetic variations associated with the diversity in rice populations is the key to breed stable and high yielding rice varieties. We performed Genome Wide Association Studies (GWAS) on 7 rice yielding traits (grain length, grain width, grain weight, panicle length, leaf length, leaf width, and leaf angle) based on 39,40,165 single nucleotide polymorphisms (SNPs) in a population of 183 rice landraces of Bangladesh. Our studies reveal various chromosomal regions that are significantly associated with different traits in Bangladeshi rice varieties. We also identified various candidate genes, which are associated with these traits. This study reveals multiple candidate genes within short intervals. We also identified SNP loci, which are significantly associated with multiple yield-related traits. The results of these association studies support previous findings as well as provide additional insights into the genetic diversity of rice. This is the first known GWAS study on various yield-related traits in the varieties of Oryza sativa available in Bangladesh, the fourth largest rice producing country. We believe this study will accelerate rice genetics research and breeding stable high-yielding rice in Bangladesh. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.30.362921v1?rss=1 Authors: Bussy, A., Patel, R., Plitman, E., Tullo, S., Salaciak, A., Bedford, S., Farzin, S., Beland, M.-L., Valiquette, V., Kazazian, C., Tardif, C., Devenyi, G., Chakravarty, M. Abstract: The study of the hippocampus across the healthy adult lifespan has rendered inconsistent findings. While volumetric measurements have often been a popular technique for analysis, more advanced morphometric techniques have demonstrated compelling results that highlight the importance and improved specificity of shape-based measures. Here, the MAGeT Brain algorithm was applied on 134 healthy individuals aged 18-81 years old to extract hippocampal subfield volumes and hippocampal shape measurements, notably : local surface area (SA) and displacement. We used linear, second or third order natural splines to examine the relationships between hippocampal measures and age. In addition, partial least squares analyses were performed to relate measurements with cognitive and demographic information. Volumetric results indicated a relative preservation of the right cornus ammonis 1 with age and a global volume reduction linked with older age, female sex, lower levels of education and cognitive performance. Vertex-wise analysis demonstrated an SA preservation in the anterior hippocampus with a peak during the sixth decade, while the posterior hippocampal SA gradually decreased across lifespan. Overall, SA decrease was linked to older age, female sex and, to a lesser extent lower levels of education and cognitive performance. Outward displacement in the lateral hippocampus and inward displacement in the medial hippocampus were enlarged with older age, lower levels of cognition and education, indicating an accentuation of the hippocampal C shape with age. Taken together, our findings suggest that vertex-wise analyses have higher spatial specifity and that sex, education and cognition are implicated in the differential impact of age on hippocampal subregions throughout its antero-posterior and medial-lateral axes. Copy rights belong to original authors. Visit the link for more info
#AunindyoChakravarty, the former #NDTVIndia and #NDTVProfit managing editor, who first revealed the TV ratings manipulation in India in 2008, on the TRP ratings scandal involving #ArnabGoswami's #RepublicTV and #RepublicBharat
This episode of Cancer Healing Journeys features an audio recording of the Healing Circle Talks with Ms Svati Chakravarty Bhatkal that took place on 13th September 2020. Read the complete article here - https://zenonco.io/events-and-activities/healing-circle-talks-ms-svati-chakravarty/ Visit our Official website- https://zenonco.io/ ZenOnco.io - Fulfilling all your cancer-related needs from diagnosis to nutrition and fitness to psychology.
Shonali Chakravarty is the Head of APAC Communications, Lenovo Data Center Group. Lenovo DCG is into the business of servers, storage, and networking infrastructure needs of organizations through intelligent transformation and enabling enterprises to harness the power of cutting edge technologies Prior to this, Shonali was the director of communications for OYO, where she helped run communications for India SA and key international markets. Before that, she has had a stint at Uber, heading policy and corporate communications for India SA. She has also spent time in the manufacturing sector having run strategic communications for Essar Group's Oil & Gas and Power divisions and earned her stripes in public policy and financial PR during her time with Marsh & McLennan companies as well as Edelman. Shonali joins us on episode 7 of the MOV Podcast to talk about her journey and the tremendous effect that videos have had on her communications at every stage in her career. She also spoke about the importance of communicating the right set of messages to your end-users and, if done correctly, how it can completely shift the dynamics of your brand. So without further ado, tune in to learn more such interesting marketing and communication insights only on the Mad Over Videos Podcast by guch featuring Shonali Chakravarty. #MOV #MadOverVideos #VideoMarketing #Marketing #communication WEBSITE: https://guch.me/ LINKEDIN: @guch https://www.linkedin.com/company/guchme/ INSTAGRAM: @guch.me https://www.instagram.com/guch.me/ FACEBOOK: @guchHQ https://www.facebook.com/guchHQ TWITTER: @guchHQ https://twitter.com/guchHQ
Before we all were participating in the Covid_19 pandemic social experiment of living like astronauts, Arnab Chakravarty had already embarked on his own journey into his own circadian rhythms. His ITP (Interactive Telecommunications Program) thesis was the culmination of months living "off the clock". In this session Arnab delves into moving away from a monochronic mindset.
Our short summary of our recent episode with AC. Original podcast description: Aritra ‘AC' Chakravarty is the Founder and CEO of Project Imagine a FinTech startup based in London. AC started his career at a large global bank, moving into numerous roles, with his latest position as the Global Head of Digital FX and Investment Products in Hong Kong. Realising that he had an appetite for risk and resonated more as a leader than a manager, he took the leap to set up his own company, Project Imagine in 2017. Social contracts, salary transparency & prioritising values over performance are at the top of his leadership agenda. Recognising the cultural shift that exists in the younger generations' desire to work for themselves at some point in their career, compared to previous generations. AC values the importance of developing social contracts with his team. Recognising that as individuals younger generations have their own aspirations and this is crucial to consider to retain the best talent. A strong team culture is present throughout the company and transparency is at the core of this, with total internal transparency over every team member's salary. Furthermore, AC discusses his value vs performance matrix and providing each team member has the right values at heart, a dip in performance will not result in disciplinary action. We discuss how this fosters a culture of improved risk taking. A fascinating discussion from a leader who has experienced a very successful career in both the corporate and start-up environments! Connect with Aritra on LinkedIn at https://www.linkedin.com/in/aritroc/ As always, thank you for listening!
Aritra ‘AC' Chakravarty is the Founder and CEO of Project Imagine a FinTech startup based in London. AC started his career at a large global bank, moving into numerous roles, with his latest position as the Global Head of Digital FX and Investment Products in Hong Kong. Realising that he had an appetite for risk and resonated more as a leader than a manager, he took the leap to set up his own company, Project Imagine in 2017. Social contracts, salary transparency & prioritising values over performance are at the top of his leadership agenda. Recognising the cultural shift that exists in the younger generations' desire to work for themselves at some point in their career, compared to previous generations, AC values the importance of developing social contracts with his team. In understanding that as individuals, younger generations have their own aspirations and this is crucial to consider to retain the best talent. A strong team culture is present throughout the company and transparency is at the core of this, with total internal transparency over every team member's salary. Furthermore, AC discusses his value vs performance matrix and providing each team member has the right values at heart, a dip in performance will not result in disciplinary action. We discuss how this fosters a culture of improved risk taking. A fascinating discussion from a leader who has experienced a very successful career in both the corporate and start-up environments! Connect with Aritra on LinkedIn at https://www.linkedin.com/in/aritroc/ As always, thank you for listening!
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.07.241497v1?rss=1 Authors: Kiesow, H., Spreng, R. N., Holmes, A. J., Chakravarty, M. M., Marquand, A. F., Yeo, B. T. T., Bzdok, D. Abstract: The complexity of social interactions is a defining property of the human species. Many social neuroscience experiments have sought to map "perspective taking", "empathy", and other canonical psychological constructs to distinguishable brain circuits. This predominant research paradigm was seldom complemented by bottom-up studies of the unknown sources of variation that add up to measures of social brain structure; perhaps due to a lack of large population datasets. We aimed at a systematic de-construction of social brain morphology into its elementary building blocks in the UK Biobank cohort (n=~10,000). Coherent patterns of structural co-variation were explored within a recent atlas of social brain locations, enabled through translating autoencoder algorithms from deep learning. The artificial neural networks learned rich subnetwork representations that became apparent from social brain variation at population scale. The learned subnetworks carried essential information about the co-dependence configurations between social brain regions, with the nucleus accumbens, medial prefrontal cortex, and temporoparietal junction embedded at the core. Some of the uncovered subnetworks contributed to predicting examined social traits in general, while other subnetworks helped predict specific facets of social functioning, such as feelings of loneliness. Our population-level evidence indicates that hidden subsystems of the social brain underpin interindividual variation in dissociable aspects of social lifestyle. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.19.162420v1?rss=1 Authors: Plitman, E., Bussy, A., Valiquette, V., Salaciak, A., Patel, R., Beland, M.-L., Tullo, S., Tardif, C., Rajah, M. N., Near, J., Devenyi, G. A., Chakravarty, M. M. Abstract: Many magnetic resonance imaging (MRI) indices are being studied longitudinally to explore topics such as biomarker detection and clinical staging. A pertinent concern to longitudinal work is MRI scanner upgrades. When upgrades occur during the course of a longitudinal MRI neuroimaging investigation, there may be an impact on the compatibility of pre- and post-upgrade measures. Similarly, subject motion is another issue that may be detrimental to longitudinal MRI work; however, embedding volumetric navigators (vNavs) within acquisition sequences has emerged as a technique that allows for prospective motion correction. Our research group recently implemented an upgrade from a Siemens MAGNETOM 3T Trio system to a Siemens MAGNETOM 3T Prisma Fit system. The goals of the current work were to: 1) investigate the impact of this upgrade on commonly used structural imaging measures and proton magnetic resonance spectroscopy indices (Prisma Upgrade protocol) and 2) examine structural imaging measures in a sequence with vNavs alongside a standard acquisition sequence (vNav protocol). In both protocols, while high reliability was observed for most of the investigated MRI outputs, suboptimal reliability was observed for certain indices. Across the scanner upgrade, increases in frontal, temporal, and cingulate cortical thickness (CT) and thalamus volume, along with decreases in parietal CT, amygdala, globus pallidus, hippocampus, and striatum volumes were observed across the Prisma upgrade, and were linked to increases in signal-to-noise ratios. No significant impact of the upgrade was found in 1H-MRS analyses. Further, CT estimates were found to be larger in MPRAGE acquisitions compared to vNav-MPRAGE acquisitions mainly within temporal areas, while the opposite was found mostly in parietal brain regions. The results from this work should be considered in longitudinal study designs and comparable prospective motion correction investigations are warranted in cases of marked head movement. Copy rights belong to original authors. Visit the link for more info
Fridays must be about Fun. So if you are a YouTuber or just someone who wants to understand making videos, we've got you Aunindyo Chakravarty. Listen to this political economist, former NDTV Anchor and Managing Editor and avid commentator help you get the grammar of video, right. Now you don't have to just listen to him, you can also ask for more, because this season we also want to hear from YOU. For a chance to feature on an episode of Good Morning Grammar. Send in your voice messages on WhatsApp at +91-9625475442 or email; Shivraj@brevis.in. If we like what we hear, we will just play them out or even feature you on your very own episode. Let's make our morning listening a little more interesting; Rate or Review by looking for Season 2 of the Brevis Living & Learning Podcast – Android - https://tinyurl.com/yc3qfhcb Apple - tinyurl.com/v8euj6z Follow us on: Twitter: https://twitter.com/ShivrajParshad Facebook: https://www.facebook.com/BrevityinourDNA/ LinkedIn: https://www.linkedin.com/company/16321692/ YouTube: https://tinyurl.com/y7uo9fcvSpotify – tinyurl.com/y766k958 Google Podcasts - https://tinyurl.com/y9fslvdb Apple Podcasts – tinyurl.com/v8euj6z TuneIn - tinyurl.com/y86pv3so iHeart Radio - https://tinyurl.com/yay4kqpa Listen Notes - https://tinyurl.com/y7d6sj9e
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.15.150052v1?rss=1 Authors: Das, T., Kamle, A., Kumar, A., Chakravarty, S. Abstract: Understanding the molecular basis of sex differences in neural response to acute hypoxic insult has profound implications for the effective prevention and treatment of ischemic stroke. Global hypoxic-ischemic induced neural damage has been studied recently under the well-controlled, non-invasive, reproducible conditions using zebrafish model. Our earlier report on sex difference in global acute hypoxia induced neural damage and recovery in zebrafish prompted us for comprehensive study on the mechanisms underlying the recovery. An omics approach for studying quantitative changes in brain proteome upon hypoxia insult following recovery was undertaken using iTRAQ-based LC-MS/MS approach. The results shed light on altered expression of many regulatory proteins in zebrafish brain upon acute hypoxia following recovery. The sex difference in differentially expressed proteins along with the proteins expressed in uniform direction in both the sexes was studied. Core expression analysis by Ingenuity Pathway analysis (IPA) showed a distinct sex difference in the disease function heatmap. Most of the upstream regulators obtained through IPA were validated at the transcriptional level. Translational upregulation of H3K9me3 in male led us to elucidate the mechanism of recovery by confirming transcriptional targets through ChIP-qPCR. The upregulation of H3K9me3 level in male at 4 hr post-hypoxia appears to affect the early neurogenic markers nestin, klf4 and sox2, which might explain the late recovery in male, compared to female. Acute hypoxia-induced sex-specific comparison of brain proteome led us to reveal many differentially expressed, which can be further studied for the development of novel targets for better therapeutic strategy. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.10.144097v1?rss=1 Authors: Das, T., Soren, K., Yerasi, M., Kamle, A., Kumar, A., Chakravarty, S. Abstract: Hypoxia the major cause of ischemia leads to debilitating disease in infants via birth asphyxia and cerebral palsy whereas in adults via heart attack and stroke. A widespread natural protective phenomenon termed Hypoxic Preconditioning occurs when prior exposures to hypoxia eventually results in robust hypoxia resistance. Accordingly we have developed a novel model of sex-specific hypoxic preconditioning in adult zebrafish to mimic the tolerance of mini strokes in human which appears to protect against the severe damage inflicted by a major stroke event. Remarkable difference in the progression pattern of neuroprotection between preconditioning hypoxia followed by acute hypoxia (PH) group, and acute hypoxia (AH) group were observed with noticeable sex difference. Since gender difference has been reported in stroke it was pertinent to investigate whether any such sex difference also exists in PHs protective mechanism against acute ischemic stroke. In order to elucidate the neural molecular mechanisms behind sex difference in neuroprotection induced by PH, a high throughput proteomics approach utilizing iTRAQ was performed, followed by protein enrichment analysis using Ingenuity Pathway Analysis. Out of thousands of altered proteins in zebrafish brain the ones having critical role either in neuroglial proliferation/differentiation or neurotrophic functions, were validated by analyzing their expression levels in PH, AH and normoxia groups. Results indicate that female zebrafish brains are more protected against the severity of AH. The study also sheds light on the involvement of many signaling pathways underlying sex difference in pre-conditioning induced neuroprotective mechanism, which can be further validated for the therapeutic approach. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.28.121343v1?rss=1 Authors: Bussy, A., Plitman, E., Patel, R., Tullo, S., Salaciak, A., Bedford, S., Farzin, S., Beland, M.-L., Valiquette, V., Kazazian, C., Tardif, C., Devenyi, G., Chakravarty, M. Abstract: The hippocampus has been extensively studied in various neuropsychiatric disorders throughout the lifespan. However, inconsistent results have been reported with respect to which subfield volumes are most related to age. Here, we investigate whether these discrepancies may be explained by experimental design differences that exist between studies. Multiple datasets were used to collect 1690 magnetic resonance scans from healthy individuals aged 18-95 years old. Standard T1-weighted (T1w; MPRAGE sequence, 1 mm3 voxels), high-resolution T2-weighted (T2w; SPACE sequence, 0.64 mm3 voxels) and slab T2-weighted (Slab; 2D turbo spin echo, 0.4 x 0.4 x 2 mm3 voxels) images were acquired. The MAGeT Brain algorithm was used for segmentation of the hippocampal grey matter (GM) subfields and peri-hippocampal white matter (WM) subregions. Linear mixed-effect models and Akaike information criterion were used to examine linear, second or third order natural splines relationship between hippocampal volumes and age. We demonstrated that stratum radiatum/lacunosum/moleculare and fornix subregions expressed the highest relative volumetric decrease, while the cornus ammonis 1 presented a relative volumetric preservation of its volume with age. We also found that volumes extracted from slab images were often underestimated and demonstrated different age-related relationships compared to volumes extracted from T1w and T2w images. The current work suggests that although T1w, T2w and slab derived subfield volumetric outputs are largely homologous, modality choice plays a meaningful role in the volumetric estimation of the hippocampal subfields. Copy rights belong to original authors. Visit the link for more info
Catching up with Shameek of Farmizen, who we interviewed 2 years ago. So much has happened but their mission is still the same: providing high quality, organic produce from zero budget natural farms to people living in the larger Indian cities. ---------------------------------------------------------- SHAKE Climate Change Does your agritech biz tackle climate change? The SHAKE Climate Change programme is again open for applicants - early stage ventures targeting carbon footprint of agriculture or food production. This is a consortium-based programme led by Rothamsted Research which offers up to £140K in start-up funds + 3 yrs mentoring. Apply by May 15th on http://shakeclimate.org Linkedin page: https://www.linkedin.com/showcase/shakeclimate/ ---------------------------------------------------------- Welcome to Investing in Regenerative Agriculture and Food. Join our Gumroad community, discover the tiers and exclusive benefits here: gumroad.com/investinginregenag Other ways to support my work: - Share the podcast - Give a 5-star rating - Or buy me a coffee… or a meal! www.Ko-fi.com/regenerativeagriculture ----------------------------------------------------------- Join me in this episode where we discuss the zero budget natural farming status in India, the issues and opportunities of organic in India and the appetite of investors for this type of farmers. Previous interview with Shameek https://soundcloud.com/investinginregenerativeagriculture/interview-shameek-chakravarty Farmizen www.farmizen.com Farmizen Neighbourhood Tribes https://www.farmizen.com/tribes/ Zero Budget Natural Farming http://apzbnf.in ----------------------------------------------------------- For feedback, ideas, suggestions please contact us through twitter, in the comments below or get in touch through the website www.investinginregenerativeagriculture.com Join the Investing in Regenerative Agriculture and Food newsletter on www.eepurl.com/cxU33P The above references an opinion and is for information and educational purposes only. It is not intended to be investment advice. Seek a duly licensed professional for investment advice.
In this podcast, Rohan tells us how he got started on his cartooning journey, what kind of impact his work has been having and the future of cartooning in climate change.
The world’s gotten a little more interested in bats over the past one month or so, since the novel coronavirus hit global headlines. In this podcast, Manisha Pande brings on board Rohit Chakravarty to discuss this much-maligned mammal. Rohit is a PhD student at the Leibniz Institute for Zoo and Wildlife Research in Berlin, Germany. He studies bats in the Himalayas of Uttarakhand, investigating how their diversity changes across elevations, what they eat and generally, how they get by in their lives in the mountains. “Bats have been living all around us for centuries…they live close to you but they know how to mind their own business,” Rohit explains. The novel coronavirus outbreak has occurred for reasons that are more manmade than naturally occuring, he says. Which means eating bats, right? Nope. Listen on and find out why. See acast.com/privacy for privacy and opt-out information.
A family outside their native place, based in Mumbai. But they keep on touch and love the family members residing in other parts of the country. They meet regularly. How does that happen? Listen to journalist, film maker Svati Chakravarti Bhatkal on The Great Indian Family, India's first family sitcom podcast. Do share your thoughts on the episode in comments or DM us on Instagram @eplogmedia Check out "The Great Indian Family" and other podcasts by Ep.Log Media on www.eplog.media See omnystudio.com/listener for privacy information.
SEASON TWO. For the first time, I'm interviewing an interesting young researcher-couple who are both experts in their fields. Pritha did her Ph.D. on the diversity patterns of the Geometridae family. Her doctoral work included the study of insect biodiversity loss due to anthropogenic disturbances in the western Indian Himalaya. My second guest is Pritha’s husband Rohit Chakravarty. He is a bat biologist currently pursuing a Ph.D. at the Institute for Zoo and Wildlife Research, Berlin. Listen to some amazing facts and stories. Truly inspiring. For more info on bats write to rohit.chakravarty77@gmail.com. For more on moths, write to dey.pritha126@gmail.com Show notes coming soon on earthymatters.blog. #listennow
Sales Operations is a known function for many organizations but it is often underutilized. In this episode, we discuss how sales operations can be most effectively utilized by using big data, understanding the customer lifetime value, and collaborating with other parts of the organization.
On this Episode Neil and Benji Chat with Neil Chakravarty and Mikey Perry about: #MuellerReport #Trump #GrowingUpin80s #Obama #Desuza #DiverseCityShow ##MinorityCoics #BeingAMinorityComedy #FirstDate #BrownLivesMatterComedyShow #relatingtoothercultures #Altcomedy #ComedyPerfomance #PickingLineUps #KareemHunt #BenRothlisberger #KobeBryant #JussieSmollet #MediaControl #Why #SportsInThe80s #impeachment #Trial #ThroneOfJokesContest --- Support this podcast: https://anchor.fm/liveatthecomedypalace/support
dozens is a new home for your money, one that that constantly helps you save and earn higher interest. It brings together a current account, a smart budgeting tool and an investment manager in one app, along with cash rewards for good financial behaviour. I spoke with the co-founder and CEO of the company, Aritra Chakravarty who shared his story with us! We hope you enjoy this episode as much as we did.
Dr. Manuel Chakravarty is a researcher and developer specializing in programming languages. In this episode he discusses the programming languages used to create the Cardano Project software. Watch Episode 14 and view more information on Youtube: https://youtu.be/MNitWQ_yhP8
Joining Iain Dale on Cross Question this week is Eve Pollard, author, journalist and a former tabloid newspaper editor; Bonnie Greer, Columnist for the New European; Dia Chakravarty, Brexit Editor for the Telegraph and Julia Langdon, political journalist and biographer.
How the regenerative agriculture revolution starts by connecting small holder farmers in rural India with customers in the city. Welcome Investing in Regenerative Agriculture, investing as if the planet mattered. Where I interview key players in the field of regenerative agriculture, people who are scaling up the sector by bringing in new money or scaling up the practises on the ground. Join our Gumroad community, discover the tiers and exclusive benefits here: https://gumroad.com/investinginregenag Other ways to support my work: - Share the podcast - Give a 5-star rating (if you podcast app allows it) - Or buy me a coffee… or a meal! www.Ko-fi.com/regenerativeagriculture Today I’m talking to Shameek Chakravarty cofounder of Farmizen based in Bangalore India, on Farmizen everyone can rent mini-plots of farmland close to the city. You choose your vegetables and farmers then grow them organically for you and you can keep track of the harvest using the app. Basically it is a real life, organic, version of Farmville. We discussed the lives of Indian farmers and what challenges they face every day and how Farmizen is trying to fix those challenges. Key points: - remove short term incentives for the farmers and they will take care of the land (farmers working with Farmizen receive 4/5 times as much and it is predictable) - historically India had a very interesting natural farming practises, like Zero budget natural farming which Farmizen is bringing back with modern technology - when you reconnect consumers with farmers and the land, trust will build Tips from Shameek for investors who want to start investing in the Regenerative Agriculture space: - have a much longer investment horizon - both India and China are very interesting markets to look at from a regenerative agriculture point of view. Their soil quality has been deteriorated significantly www.farmizen.com Recent Bloomberg item about Farmizen: www.youtube.com/watch?v=VjlUnPhTio8 Please hit the share button if you think this interview is relevant for someone you know! If you want to receive an email when I upload a new episode, subscribe here eepurl.com/cxU33P The above references an opinion and is for information and educational purposes only. It is not intended to be investment advice. Seek a duly licensed professional for investment advice.
I have known Gandhar since around 2003. He is an interesting man with a lot of colorful stories to tell. I attended his Ph.D defense a few years ago and always enjoy picking his brain about religion and philosophy.
In my time doing this podcast, I've covered a number of books about transitional justice. All have been insightful and interesting. But few of them focused carefully on the trials themselves. Anuradha Chakravarty seeks to remedy this. Her book Investing in Authoritarian Rule: Punishment and Patronage in Rwanda's Gacaca Courts for Genocide Crimes (Cambridge University Press, 2016) looks carefully at the processes and people involved in Rwanda's Gacaca courts. She looks at the recruitment and training of judges. She looks at the incentives offered for denouncing others as genocidaires. And she examines the ways in which the incentives and context led many defendants to confess. In doing so, Chakravarty significantly advances our understanding of the workings of transitional justice in Rwanda. But she also uses Rwanda as a lens to try and understand the challenges faced by authoritarian leaders. She argues that the RPF engaged in a kind of clientalistic bargaining with Hutus. By offering targeted grants of clemency and patronage to defendants and to those who denounced others, the RPF secured its political control over Rwanda as a whole. Chakravarty argues that other autocratic leaders have often used a similar strategy of “authoritarian clientelism” to secure their power. It's a persuasive argument. Kelly McFall is Associate Professor of History at Newman University in Wichita, Kansas, where he directs the Honors Program. He is particularly interested in the question of how to teach about the history of genocides and mass atrocities and has written a module in the Reacting to the Past series about the UN debate over whether to intervene in Rwanda in 1994.
In my time doing this podcast, I’ve covered a number of books about transitional justice. All have been insightful and interesting. But few of them focused carefully on the trials themselves. Anuradha Chakravarty seeks to remedy this. Her book Investing in Authoritarian Rule: Punishment and Patronage in Rwanda’s Gacaca Courts for Genocide Crimes (Cambridge University Press, 2016) looks carefully at the processes and people involved in Rwanda’s Gacaca courts. She looks at the recruitment and training of judges. She looks at the incentives offered for denouncing others as genocidaires. And she examines the ways in which the incentives and context led many defendants to confess. In doing so, Chakravarty significantly advances our understanding of the workings of transitional justice in Rwanda. But she also uses Rwanda as a lens to try and understand the challenges faced by authoritarian leaders. She argues that the RPF engaged in a kind of clientalistic bargaining with Hutus. By offering targeted grants of clemency and patronage to defendants and to those who denounced others, the RPF secured its political control over Rwanda as a whole. Chakravarty argues that other autocratic leaders have often used a similar strategy of “authoritarian clientelism” to secure their power. It’s a persuasive argument. Kelly McFall is Associate Professor of History at Newman University in Wichita, Kansas, where he directs the Honors Program. He is particularly interested in the question of how to teach about the history of genocides and mass atrocities and has written a module in the Reacting to the Past series about the UN debate over whether to intervene in Rwanda in 1994. Learn more about your ad choices. Visit megaphone.fm/adchoices
In my time doing this podcast, I’ve covered a number of books about transitional justice. All have been insightful and interesting. But few of them focused carefully on the trials themselves. Anuradha Chakravarty seeks to remedy this. Her book Investing in Authoritarian Rule: Punishment and Patronage in Rwanda’s Gacaca Courts for Genocide Crimes (Cambridge University Press, 2016) looks carefully at the processes and people involved in Rwanda’s Gacaca courts. She looks at the recruitment and training of judges. She looks at the incentives offered for denouncing others as genocidaires. And she examines the ways in which the incentives and context led many defendants to confess. In doing so, Chakravarty significantly advances our understanding of the workings of transitional justice in Rwanda. But she also uses Rwanda as a lens to try and understand the challenges faced by authoritarian leaders. She argues that the RPF engaged in a kind of clientalistic bargaining with Hutus. By offering targeted grants of clemency and patronage to defendants and to those who denounced others, the RPF secured its political control over Rwanda as a whole. Chakravarty argues that other autocratic leaders have often used a similar strategy of “authoritarian clientelism” to secure their power. It’s a persuasive argument. Kelly McFall is Associate Professor of History at Newman University in Wichita, Kansas, where he directs the Honors Program. He is particularly interested in the question of how to teach about the history of genocides and mass atrocities and has written a module in the Reacting to the Past series about the UN debate over whether to intervene in Rwanda in 1994. Learn more about your ad choices. Visit megaphone.fm/adchoices
In my time doing this podcast, I’ve covered a number of books about transitional justice. All have been insightful and interesting. But few of them focused carefully on the trials themselves. Anuradha Chakravarty seeks to remedy this. Her book Investing in Authoritarian Rule: Punishment and Patronage in Rwanda’s Gacaca Courts for Genocide Crimes (Cambridge University Press, 2016) looks carefully at the processes and people involved in Rwanda’s Gacaca courts. She looks at the recruitment and training of judges. She looks at the incentives offered for denouncing others as genocidaires. And she examines the ways in which the incentives and context led many defendants to confess. In doing so, Chakravarty significantly advances our understanding of the workings of transitional justice in Rwanda. But she also uses Rwanda as a lens to try and understand the challenges faced by authoritarian leaders. She argues that the RPF engaged in a kind of clientalistic bargaining with Hutus. By offering targeted grants of clemency and patronage to defendants and to those who denounced others, the RPF secured its political control over Rwanda as a whole. Chakravarty argues that other autocratic leaders have often used a similar strategy of “authoritarian clientelism” to secure their power. It’s a persuasive argument. Kelly McFall is Associate Professor of History at Newman University in Wichita, Kansas, where he directs the Honors Program. He is particularly interested in the question of how to teach about the history of genocides and mass atrocities and has written a module in the Reacting to the Past series about the UN debate over whether to intervene in Rwanda in 1994. Learn more about your ad choices. Visit megaphone.fm/adchoices
In my time doing this podcast, I’ve covered a number of books about transitional justice. All have been insightful and interesting. But few of them focused carefully on the trials themselves. Anuradha Chakravarty seeks to remedy this. Her book Investing in Authoritarian Rule: Punishment and Patronage in Rwanda’s Gacaca Courts for Genocide Crimes (Cambridge University Press, 2016) looks carefully at the processes and people involved in Rwanda’s Gacaca courts. She looks at the recruitment and training of judges. She looks at the incentives offered for denouncing others as genocidaires. And she examines the ways in which the incentives and context led many defendants to confess. In doing so, Chakravarty significantly advances our understanding of the workings of transitional justice in Rwanda. But she also uses Rwanda as a lens to try and understand the challenges faced by authoritarian leaders. She argues that the RPF engaged in a kind of clientalistic bargaining with Hutus. By offering targeted grants of clemency and patronage to defendants and to those who denounced others, the RPF secured its political control over Rwanda as a whole. Chakravarty argues that other autocratic leaders have often used a similar strategy of “authoritarian clientelism” to secure their power. It’s a persuasive argument. Kelly McFall is Associate Professor of History at Newman University in Wichita, Kansas, where he directs the Honors Program. He is particularly interested in the question of how to teach about the history of genocides and mass atrocities and has written a module in the Reacting to the Past series about the UN debate over whether to intervene in Rwanda in 1994. Learn more about your ad choices. Visit megaphone.fm/adchoices
In my time doing this podcast, I’ve covered a number of books about transitional justice. All have been insightful and interesting. But few of them focused carefully on the trials themselves. Anuradha Chakravarty seeks to remedy this. Her book Investing in Authoritarian Rule: Punishment and Patronage in Rwanda’s Gacaca Courts for Genocide Crimes (Cambridge University Press, 2016) looks carefully at the processes and people involved in Rwanda’s Gacaca courts. She looks at the recruitment and training of judges. She looks at the incentives offered for denouncing others as genocidaires. And she examines the ways in which the incentives and context led many defendants to confess. In doing so, Chakravarty significantly advances our understanding of the workings of transitional justice in Rwanda. But she also uses Rwanda as a lens to try and understand the challenges faced by authoritarian leaders. She argues that the RPF engaged in a kind of clientalistic bargaining with Hutus. By offering targeted grants of clemency and patronage to defendants and to those who denounced others, the RPF secured its political control over Rwanda as a whole. Chakravarty argues that other autocratic leaders have often used a similar strategy of “authoritarian clientelism” to secure their power. It’s a persuasive argument. Kelly McFall is Associate Professor of History at Newman University in Wichita, Kansas, where he directs the Honors Program. He is particularly interested in the question of how to teach about the history of genocides and mass atrocities and has written a module in the Reacting to the Past series about the UN debate over whether to intervene in Rwanda in 1994. Learn more about your ad choices. Visit megaphone.fm/adchoices
Donna has a question, Meredith has a shock, Gary gets a return, Laarsen needs a new window and Chakravarty smells no tail.
SynTalk thinks about the deep historical and ongoing interrelationships between (the all pervasive & incessantly productive) images, and concepts & words. We make the widely sweeping journey from ancient rock art to the Coca-Cola logo to images on monitors in hospitals, to possible futures (say) a 1000 years out. The concepts are derived off / from ‘Lingo Dev’, Aristotle, Hippodamus of Miletus, Freud, Saussure, Peirce, Derrida, Foucault, Le Corbusier, McLuhan, Debord, & Baudrillard, among others. Can concepts or conceptual entities come to be without language? What are the links between rock art, and speech, script, words, entoptic phenomena, induced phosphene images, catenary curves, ‘scene of experience’, & language? Do 100,000+ years old rock arts provide a promising clue to how meaning gradually emerged from the pre-conceptual pre-representational ‘cauldron’? Are letters and pictures interchangeable, and have they always been so? How images come from very ancient times and how they thrust forward from without and from within? Do we dream in images? Is there any logo which is non iconic? How the core pursuit of advertising is to give form to an abstraction. How does advertising tackle different media, & how an advertisement in the print necessarily needs to be ‘processed in the mind’? How do you create the concept of ‘Friday dressing’? How Jarawas (from Andamans) have come to use words from English or Hindi. Does extinction of languages lead to death of concepts, & the attendant phenomena of amnesia and aphasia? We discuss Egyptian, Mesopotamian, Phoenician, Greek, & Chinese scripts. How icons (& further images, diagrams & metaphors), index & symbols are different from each other? How is a notion different from a concept? Is there conflict and cooperation always at play between images (of say, Batman, Hanuman, Manga, or Anime), & are images conquering the world? Where do specters and ghosts come from? Is there an incessant mass-ification of images (via ‘procession of the simulacra’) ongoing and ahead of us, & are images the long term future of language? Are images & meanings going to be increasingly crowd sourced in the future? Is a technology-driven ‘master narrative’ taking over the visual arts, cities, & forests, and is the ‘visual landscape’ shrinking? The SynTalkrs are: Dr. K. K. Chakravarty (art, public administration, Lalit Kala Akademi, Delhi), Santosh Desai (advertising, strategy, Futurebrands, ex-McCann-Erickson, Delhi), & Prof. Franson D. Manjali (semiotics, interdisciplinary, JNU, Delhi).
At the 2014 August CocoaHeads meetup in Sydney we were verty fortunate to have Manuel Chakravarty give us a talk titled “Swift—Adopting functional programming”. Manuel is an internationally renowned expert on functional programming based here in Sydney. Manuel is this year’s…Read more ›
Jana of the Jungle hosts Siddharth Chakravarty, Captain of Sea Shepherd Conservation Society's My Steve Irwin live from Australia. Siddarth talks about his experiences in the campaign in Antartica to saving whales from Japanese illegal whaling in a Sanctuary to protect whales. Siddarth is in charge of the vessel, oversees the vessel safety, navigation, campaign planning and strategies with the other captains on campaigns. A riveting interview as plans are made for the upcoming Campaign Relentless.
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