Podcasts about Matched

(3:00) Belated thoughts about the ACC Baseball Tournament(9:00) Regional field set; seems reasonable(24:00) How to use Joey Volini in the postseason?(28:00) Matched up with Corvallis Regional(32:00) SEC absolutely dominates Selection Monday(40:00) Softball falls to Texas Tech(47:00) NiJaree Canady. Kinda worth a mil.(52:00) FSU ranked 13th best team since 2000. Eh.Music: Creed - My Sacrificevitaminenergy.com | Shake it and take it!

(3:00) Belated thoughts about the ACC Baseball Tournament(9:00) Regional field set; seems reasonable(24:00) How to use Joey Volini in the postseason?(28:00) Matched up with Corvallis Regional(32:00) SEC absolutely dominates Selection Monday(40:00) Softball falls to Texas Tech(47:00) NiJaree Canady. Kinda worth a mil.(52:00) FSU ranked 13th best team since 2000. Eh.Music: Creed - My Sacrificevitaminenergy.com | Shake it and take it!

Another day well spent doubling your paychecks, plus we heard about the crippy crap your partner brings home, you woke up to something crazy, and we Mixed & Matched the tattoos we'd get to scan out faster at the grocery store. We've got more paychecks to double on Thursday, so make sure you're signed up at the link below! Catch up on everything you missed from today's show on The Morning Mix Podcast!Follow The Mix: The MixstagramGet Your Paycheck Doubled: Sign Up Today!Get the Free MIX App: Stream The MixSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Sickle cell disease was thought to be cured using gene therapy, but longer term follow up reveals that while the condition improves many are not cured. Now a new approach developed at Johns Hopkins and around the world uses ‘half-matched' … Sickle cell disease should be treated with a half-matched donor approach, Elizabeth Tracey reports Read More »

This week's topics include treating resistant hypertension, gabapentanoids and the risk of self harm, risk for depression after diagnosis of a medical condition, and fatty liver and pregnancy.Program notes:0:35 Depression after medical condition diagnosis1:36 Any of a number of medical conditions2:37 A much lower risk in comparison group3:37 Major depressive disorder could be number one cause of YLL4:01 Fatty liver and pregnancy outcomes5:01 Matched to those with obesity or T2D6:01 Screening general population not indicated7:00 Gabapentanoids and risk of self harm8:01 Rates of self harm variable 9:04 Use has increased fourfold10:00 Treatment of resistant hypertension11:01 Spironolactone or amiloride12:33 End

Welcome back to another episode of Midwest Married. Maintaining a happy/healthy relationship, kids, friendship, intimacy and everything else that could come at you in this crazy thing we call life. Buckle up—our third episode of listener write-ins takes us everywhere. We kick things off with the excitement of moving out at 18... but make it spicy by adding a significant other to the mix. Nothing tests young love quite like sharing bills, chores, and passive-aggressive texts from your mom. Next, we take a serious turn as a listener asks if they should reconnect with a former role model who has since... well, unalived someone. It's a tough one, and we try our best to walk the fine line between thoughtful advice and not spiraling into a true crime podcast. Finally, we dive into one of the internet's most controversial questions: is it ever okay to propose at, or around, someone else's wedding?  As always: awkward laughs, questionable advice, and zero regrets. Submit your personal write-ins or issues to us!!: https://docs.google.com/forms/d/e/1FAIpQLSeoO0au8ykFtaJ-FdF10iLXEa4LkHiLlWDk6ra6CRfAGqyhLg/viewform Full length video episodes on YouTube: https://www.youtube.com/@MidwestMarriedPodcast/f Follow us on Instagram: https://www.instagram.com/midwestmarried/ Anything else you may need :) https://linktr.ee/midwestmarried

Join Rachel and Sanaya, recently matched M4s, as they share reflections and advice about the residency application process. Timestamps:Writing application, personal statement 1:00Where to apply, signaling 9:50Interviews 21:20 Ranking 26:50Quick notes on SOAP 32:20 Takeaways 33:00 Resources:AAMC Report on SignalsResidency Prep EpisodeMatch 2023 EpisodeSOAP Episode

Sirolimus-coated Balloon Vs. Drug-eluting Stent in Elderly Patients with Coronary Artery Disease: A Propensity-score Matched Comparison

Every shed hunter knows the feeling: the exhilaration of picking up an antler and the instant curiosity about where the other side might be located. It could be resting a few feet away; it could be hidden in a brushy draw a half mile away, or it could be in the next county. There's no way of knowing for certain—but new research may offer some clues. Researchers at the University of Nebraska Kearney recently finished a 13-year study that aimed to...

Elevated Man Podcast with Apollonia Ponti  Why 95% of Men Get ZERO Matches on Dating Apps (8 Tips To Start Getting Matched Today!) Tired of endlessly swiping with little to show for it? You're not alone. In this podcast, Apollonia Ponti will take an honest look at the challenges men face on dating apps. From intense competition to the emphasis on appearance over connection, we break down the key reasons why meaningful matches can be so hard to find. Whether you're experienced with online dating or just curious about what's really going on, this video offers valuable insights into the digital dating landscape. Sit back, and let's explore why dating apps often fall short—for men in particular! Key points in this episode! 0:53 - Why do woman and men have different dating experience.  1:48 - Most men doesn't know how to build their profile. Here's why.  2:54 - Consistency is not all about the matches. Is the quality of matches.  3:10 - The common mistake on online dating. 4:19 - Most men use online dating to see who is more attractive.  5:18 - Here is how you should approach online dating.  6:04 - Invest in good photos. 7:06 - Write a bio that sparks their curiosity.  8:27 - Chasing vs pursuing someone online. What is the difference? 9:40 - The woman isn't showing interest. Move on.   "I love Apollonia; her tips have helped me with my dating!" , scroll to the bottom to Rating & Reviews, and click on Write a Review.   Book A Coaching Call With Apollonia and her Team! Book A Free Dating Evaluation Call HERE! Book a free Agthormion of Attraction call!  Free eBook:  7 Common Mistakes Men Make When Attracting a Woman Want more dating advice? Follow Apollonia On:  Instagram; https://www.instagram.com/apollonia_ponti/?hl=en Facebook; https://m.facebook.com/apollonialovecoach YouTube; https://m.youtube.com/channel/UCYqdbnuvx-jJZByotoNW-5Q Website; https://www.apolloniaponti.com/ Listen and Subscribe to the Write Your Legend Podcast with Apollonia Ponti on iTunes, Spotify, Stitcher, and the CLNS Media Network mobile app.

As the Supreme Court weighs in on the president's use of the Alien Enemies Act, Mary and Andrew approach this week's developments with both concern and relief. While relieved at the unanimity of the High Court's belief that due process is a necessity, the concern lies with the Trump administration's response to a court order directing them to arrange the return of Kilmar Abrego Garcia, the man who was wrongfully deported to El Salvador. They also see cause for alarm after the government retaliated against their own lawyer in this case. Andrew and Mary then take a beat to spotlight the DC circuit upholding a judge's decision related to scope of Trump's J6 pardons. And before closing out this week's episode, they detail the lawsuit brought by the conservative leaning NCLA over the constitutionality of the sweeping tariffs the president has announced.Further reading: This is Mary's recent op Ed in the Washington Post: The White House war on Big Law hits some speed bumpsAnd please vote for your favorite MSNBC podcasts in this year's Webby Awards:Prosecuting Donald Trump in the Podcasts - Crime & Justice category: VOTE HEREWhy Is This Happening? With Chris Hayes in the Podcasts - Interview/Talk Show category: VOTE HEREInto America: Uncounted Millions in the Podcasts - News & Politics category: VOTE HEREVoting closes April 17th.Want to listen to this show without ads? Sign up for MSNBC Premium on Apple Podcasts.

Hello! It's time for The Monday Show with Andrew and Aaron sponsored by NORD VPN. Andrew and Aaron look back on Saturday's cup parade and how it will stay with them for life, and why it's such a fantastic sales pitch for the club. There's also a discussion about Matheus Cunha, Kieran Trippier and much more. Learn more about your ad choices. Visit megaphone.fm/adchoices

Check out Dreamdata.io for your free trial!In this episode, Steffen Hedebrandt, CMO and co-founder of Dreamdata, discusses how B2B companies can solve the complex challenge of marketing attribution. He explains how Dreamdata connects siloed data to reveal which campaigns actually drive revenue, offering marketers a clear picture of long, multi-touch customer journeys. Steffen also shares insights on audience targeting, real-time buying signals, and how AI is being integrated meaningfully into the platform.Guest BioSteffen Hedebrandt is the Chief Marketing Officer at Dreamdata, a leading Revenue Attribution Platform that enables B2B marketing teams to optimize and automate their marketing efforts with confidence.A seasoned marketing leader known for his no-nonsense, results-oriented approach, Steffen has a proven track record of scaling companies and building high-performing teams at Upwork and Airtame. With hands-on experience in tackling the challenges of rapid growth, he understands what it takes to drive success in today's fast-paced marketing environment.TakeawaysB2B marketing requires a different approach than B2C.Understanding customer journeys is crucial for effective marketing.Data silos can complicate the analysis of customer journeys.AI can enhance marketing efforts but should not be a gimmick.Attribution is key to understanding campaign effectiveness.Marketers should focus on the buying committee in B2B sales.Optimizing ad spend based on actual sales data is essential.Dream Data provides tools for tracking and analyzing customer journeys.Success stories highlight the effectiveness of data-driven marketing.Proactive marketing is necessary to support sales teams.Chapters00:00 Introduction to Steffen Hedebrandt & Dreamdata01:03 The origins of Dreamdata and solving B2B attribution02:44 Founding team dynamics and early challenges04:07 Complexities of B2B journeys vs B2C05:01 Key problems Dreamdata solves for B2B marketers06:55 Importance of ICP and tech integrations08:18 Common CRM systems used and data quality challenges09:33 Solving wasted budget and campaign ROI10:31 Account-based timelines and stakeholder insights11:20 Campaign-level ROI visibility and optimization12:38 Deal size variation and applicability across companies13:31 Real-time signals and proactive sales alerts14:59 Tracking without gating using IP resolution16:00 Engagement scoring vs lead scoring17:24 AI integration and feature roadmap at Dreamdata19:31 The value of AI as a means, not the end21:04 Solving the attribution problem in B2B22:48 First-touch attribution vs CRM default models23:32 Dealing with non-trackable marketing activities25:19 Tips for qualitative evidence and journey enrichment26:11 Case study: Insight Software and optimizing ad spend27:54 Audience Hub and hyper-targeted campaigns28:45 Matched audiences vs lookalikes on LinkedIn30:40 Free tools and benchmark reports from Dreamdata32:27 Benchmark: 211-day average B2B customer journey33:19 Understanding the B2B buying committee35:14 Where to find Steffen and the benchmark report36:13 Offline conversions and smarter ad training37:28 Attribution loops and campaign optimization38:47 20% CPA reduction through LinkedIn integration39:31 Wrap-upLinkedIn⁠⁠⁠⁠Follow Steffen Hedebrandt on LinkedIn here⁠⁠⁠⁠⁠⁠⁠⁠Follow Justin on LinkedIn hereBook a call with Justin on how to get into⁠⁠⁠ business video podcasting ⁠⁠

We know finding love can be hard. You might have tried everything, Tinder, Grinder perhaps your colleagues even tried hooking you up and all even after all of this you have had no luck. Well…We have scientifically figured out a way to get you the perfect partner. Call us now tell us what your greatest song of all time is? If this song resonates with other single Joburgers they will call us and submit their songs and we will match you up.See omnystudio.com/listener for privacy information.

Commentary by Dr.  Jian'an Wang

Mailbag Monday!

Daily Dad Jokes (01 Feb 2025)The official Daily Dad Jokes Podcast electronic button now available on Amazon. The perfect gift for dad! Click here here to view!Email Newsletter: Looking for more dad joke humour to share? Then subscribe to our new weekly email newsletter. It's our weekly round-up of the best dad jokes, memes, and humor for you to enjoy. Spread the laughs, and groans, and sign up today! Click here to subscribe!Listen to the Daily Dad Jokes podcast here: https://dailydadjokespodcast.com/ or search "Daily Dad Jokes" in your podcast app.Interested in Business and Finance news? Then listen to our sister show: The Daily Business and Finance Show. Check out the website here or search "Daily Business and Finance Show" in your podcast app.Jokes sourced and curated from reddit.com/r/dadjokes.Joke credits: ilikesidehugs, Manofleisure75, AdorablexGirl, Man-e-questions, Joel_Boyens, MickeySwank, Far-Device-9391, khoipham0705, SamiSiren, Recent-Role1389, jfshay, Realistic-Twist-3112, , Left-Distribution-13, Odd-Mention6294, DinglebarryHandpump, threetwopun, vilebunny, No-Bed-1829, Prophet_Of_LossSubscribe to this podcast via:iHeartMediaSpotifyiTunesGoogle PodcastsYouTube ChannelSocial media:InstagramFacebookTwitterTikTokDiscordInterested in advertising or sponsoring our show? Contact us at mediasales@klassicstudios.comProduced by Klassic Studios using AutoGen Podcast technology (http://klassicstudios.com/autogen-podcasts/)See omnystudio.com/listener for privacy information.

Does getting upset for who you get on MAFS pass the pub test?See omnystudio.com/listener for privacy information.

Behind the wheel of the Mercedes-Benz CLE 300 4 MATIC Coupe – a ratherhandsome two door Coupe on a long-wheelbase - powered by a 2.0-litre turbofour-cylinder petrol engine assisted by a 48-volt mild hybrid system mated to anine-speed automatic driving all four wheels. Ownership rather exclusive withjust 499 sold last year – priced at $124,900 plus on-road costs. So how does itdrive - the petrol engine delivers 190kW of power, 400 Nm of torque, the hybridsystem contributing more power and torque under hard acceleration – the pairingimproving fuel efficiency and I managed 7.9L/100KM, not bad for a rather heavycoupe on 95 grade petrol. Sharing its underpinnings with the latest C-Class andE-Class sedan but with an AMG-inspired sports suspension that is 15mm lowerand with calibrated steering that varies in each of the four drive modes - alongwith sharper gear shifts this is a sports coupe with real driving appeal. Ridequality however can get a little hard, the real surprise, the amount of noiseintrusion into the cabin on a harsh surface, something I wouldn’t expect on a carat this value. But overall, the new Mercedes-Benz CLE 300 coupe a very polishedperformer. I’m David BerthonSee omnystudio.com/listener for privacy information.

She Matched with a Friend's Ex by Maine's Coast 93.1

Meridian Convention Center (+1 336-218-6470) is offering wedding decor rental packages to suit every style and budget. Find out how you can help save the environment, and your money, with Meridian Convention Center's wedding decor rental packages at https://meridianconvention.com Meridian Convention Center City: Greensboro Address: 312 W Meadowview Rd Website: https://meridianconvention.com/

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In this podcast episode, Ruchika Talwar, MD, sits down with Rick Baehner, MD, Chief Medical Officer of Precision Oncology at Exact Sciences and Clinical Professor of Pathology at University of California, San Francisco, to discuss the importance of ultra-comprehensive genomic profiling in advanced cancer therapy selection. The two talk about the OncoExTra® test from Exact Sciences, which includes whole-exome DNA sequencing and whole-transcriptome RNA sequencing, and how the latest updates to industry guidelines will continue to influence approaches to cancer care.

New York police now say the 3D-printed gun that CEO killing suspect Luigi Mangione had when he was arrested in Pennsylvania this week matches shell casings at the crime scene. Mangione's fingerprints also match those investigators found on items near the scene, NYPD Commissioner Jessica Tisch said on Wednesday. Plus, a clearer timeline on when Mangione's mother reported him missing and when at that time she said she last spoke with him. And, for weeks, mysterious drones have been flying low over parts of New Jersey. Our Gary Tuchman has video of some of the drones and shares what officials are saying about the sightings. Learn more about your ad choices. Visit podcastchoices.com/adchoices

It's the company every trader knows. Nvidia (NVDA) nearly tripled its stock value since the start of 2024 despite showing some price weakness after the U.S. presidential election. Tony Zipparro weighs if Nvidia "is a good trade right now." He's optimistic the company's P/E ratio will balance out in the next year, though one headwind up in the air is China's anti-monopoly probe into Nvidia. ======== Schwab Network ======== Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribe Download the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185 Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7 Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watch Watch on Vizio - https://www.vizio.com/en/watchfreeplus-explore Watch on DistroTV - https://www.distro.tv/live/schwab-network/ Follow us on X – https://twitter.com/schwabnetwork Follow us on Facebook – https://www.facebook.com/schwabnetwork Follow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

Hear the story behind Jeremy Wray's legendary gap jump, one of the most iconic moments in skateboarding history. Find out how he prepared for it, why it's never been done since and the unforgettable experiences that shaped his career from stunt doubling for Tony Hawk to some crazy injuries! Control Body Odor ANYWHERE with @shop.mando and get $5 off off your Starter Pack (that's over 40% off) with promo code [HAWK] at shopmando.com! #mandopod Download Prize Picks today and use code HAWKWOLF to get $50 instantly after you play your first $5 lineup! Got to alphaprogression.com/HAWK to get 20% off your first payment Learn more about your ad choices. Visit megaphone.fm/adchoices

Hear the story behind Jeremy Wray's legendary gap jump, one of the most iconic moments in skateboarding history. Find out how he prepared for it, why it's never been done since and the unforgettable experiences that shaped his career from stunt doubling for Tony Hawk to some crazy injuries! Control Body Odor ANYWHERE with @shop.mando and get $5 off off your Starter Pack (that's over 40% off) with promo code [HAWK] at shopmando.com! #mandopod Download Prize Picks today and use code HAWKWOLF to get $50 instantly after you play your first $5 lineup! Got to alphaprogression.com/HAWK to get 20% off your first payment Learn more about your ad choices. Visit megaphone.fm/adchoices

If you're dreaming about leaving your 9-to-5 to build a business, but you're unsure where to start, I get it. Nearly 10 years ago, I was in your shoes—working long hours as a CMO, feeling unfulfilled, and wondering how I could create a life on my terms. In this episode, I'm sharing exactly how I made the leap to full-time entrepreneurship, including the hard lessons I learned along the way and the strategies that worked. If you're ready to start making moves toward freedom, this episode will give you the roadmap to get there. What You'll Learn in This Episode: Why Setting Financial Goals Is Essential: I'll explain how I made my side hustle match my day job income for three months before making the leap. The Power of Resourcefulness: You'll hear how I maximized my limited time, from recording podcasts at 5 a.m. to turning my day job into a paying client. How to Test Income Streams Before You Quit: I'll walk you through why experimenting with coaching, consulting, and courses helped me discover what I loved—and what I didn't. The Importance of Mentors: I'll share why investing in masterminds and personal growth made the difference in scaling my business. How to Use Your Day Job as an Advantage: I'll reveal the strategies I used to leverage my corporate role to fuel my entrepreneurial journey. Ready to take action? Join me for my free Side Hustle to Six Figures masterclasses at SideToSix.com. Let's make 2025 the year you take the leap!

If you're worried about immune rejection when considering stem cell therapy, then this is THE episode for you.As you know, stem cell therapy can be overwhelming, and when you bring matching into it, you might start thinking that it's too complex for you to understand.But this is why I'm here—in this episode, I'll help you answer one simple question: If I'm getting stem cell therapy, does the doctor need to match the stem cells to me?Many people assume that stem cell therapy requires a perfect match for it to be effective. But what if I told you that's not the case?Curious to know more? Then make sure to tune in now!Key Takeaways:Introduction (00:00)Do you need to match stem cells? (00:44)When stem cells don't need to be matched to you (01:39)Young cells vs older cells (07:47)Additional Resources:✨ Learn more about how to live a long and pain-free life: www.drjoykong.com —Dr. Joy Kong is a regenerative medicine and anti-aging expert. Her podcast is part of her mission to reduce suffering and elevate happiness. Join us every week for the latest holistic health insights that will help you live a long and pain-free life.

Today, on Hook of a Book, I review Matched, by Allie Condie! Instagram: @hookofabook Goodreads: Ellie Mano Email: hookofabookpodcast@gmail.com

What are the 4Qs? (1) Three favorite films. (2) An underrated film. (3) An overrated film. (4) A lesser-known film people should seek out. Tuesday's interview with Regina Pigsley was two years in the making and well worth the wait! Her film “The Phoenix” screened at the Sherman Oaks Film Festival and won Outstanding Director – Drama & Audience Award - Best Short Film – Drama and six months later brought her revamped college film “Matched” to Film Invasion Los Angeles in 2023, taking home an Audience Award for Best Short Film - SciFi. Regina is an all around amazing person and you know that means you're going to want to tune in for her 4 Questions. More about Regina at https://www.reginapigsley.com IG- @reginapigs _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Discover Indie Film Website – Instagram – Facebook – X/Twitter The INDIE Channel The INDIE Channel Website – Instagram – Facebook – X/Twitter – TikTok

Today Tim is joined by Chloe & Joel to chat Super data matching along with irrational fears.  With no Dan in the house, it's a loose one. Strap in Drunk Fam!

It's Tuesday, Indie Film Lovers, and you know that means a new podcast is out! This particular interview was two years in the making! How so? Regina Pigsley and I had set a time to record this, either in person or Zoom, so many times since her film “The Phoenix” screened at Sherman Oaks Film Festival in 2022 (where she won Outstanding Director – Drama & Audience Award - Best Short Film – Drama) that we both thought that we were recording her second appearance on Discover Indie Film. But noooo... thorough research proves that Regina has not been on the podcast before! It might be because we had another great festival Q&A six months later when she brought her revamped college film “Matched” to Film Invasion Los Angeles in 2023, taking home an Audience Award for Best Short Film - SciFi. But our shared false memory that Regina had done a Discover Indie Film podcast is no longer relevant because we DID record this podcast! Lucky you, because this is a wonderful conversation with an amazingly dedicated filmmaker and human. I add the “amazing human” part because Regina works for World Central Kitchen, utilizing her production skills to help get food to people in war zones. Amazing! Learn more about Regina at https://www.reginapigsley.com IG- @reginapigs _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Discover Indie Film Website – Instagram – Facebook – X/Twitter The INDIE Channel The INDIE Channel Website – Instagram – Facebook – X/Twitter – TikTok

If a couple discovers that they both have the same love language, it's easier on their relationship. However, they may have a preferred way of expressing their love within that shared love language.See omnystudio.com/listener for privacy information.

Ally Condie is the author of the No. 1 New York Times bestselling Matched series and the Edgar Award Finalist for "Summerlost," among other novels.

In this JCO Article Insights episode, Alexandra Rojek provides a summary on "Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors" by Schaffer et al published in the Journal of Clinical Oncology July 17th, 2024. TRANSCRIPT Alexandra Rojek: Hello and welcome to JCO Article Insights. I'm your host, Alexandra Rojek, and today we will be discussing an original report published in the October 1st issue of JCO titled, “Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors,” by Shaffer et al. The CIBMTR registry study set out to compare outcomes of patients undergoing allogeneic stem cell transplantation hematologic malignancies by HLA antigen matching status as well as by the type of GVHD prophylaxis regimen received either calcineurin inhibitor-based prophylaxis or post-transplant cyclophosphamide or PTCy. This study included patients reported to CIBMTR from January 2017 to June 2021 with AML, ALL or MDS, and required that they have undergone allotransplant with either a calcineurin inhibitor based so tacro or cyclosporine, GVHD prophylaxis, or PTCy, which included a calcineurin inhibitor or sirolimus with or without MMF and ATG. Matched unrelated donors were defined as an 8 out of 8 HLA match. And mismatched unrelated donors were defined as HLA mismatched at any single locus or 7 out of 8. The primary objective of the study aimed to compare overall survival or OS and GVHD and relapse-free survival (GRFS) within and between matched unrelated donors versus mismatched unrelated donors separated by calcineurin inhibitor versus PTCy based GVHD prophylaxis. GRFS was defined as survival without grade 3 to 4 acute GVHD, moderate to severe chronic GVHD requiring systemic therapy or relapse. 10,025 patients were included from 153 centers, with a median follow up of over 36 months. Mismatched unrelated donor recipients were made up of 22% minority ancestry patients as compared to just 8% of patients receiving a matched unrelated donor allo transplant, showing an enrichment for patients of minority ancestry in the mismatched unrelated donor group. Just under 10% of patients were of minority ancestry in the study overall, reflective of challenges in transplant care for these patients, which may include inferior access to care, fewer available and suitably matched donors, among other factors. 54% of all patients were transplanted for AML and 29% for MDS. 45% of patients received myeloablative conditioning, 25% received regimens containing ATG, and 23% overall received PTCy with either a calcineurin inhibitor or sirolimus as well as MMF. Among patients receiving PTCy, the authors did not find differences in overall survival by degree of HLA matching, whereas among patients receiving calcineurin inhibitor-based prophylaxis, there remained survival differences by HLA matching status. When comparing matched unrelated donor calcineurin inhibitor patients with PTCy matched unrelated donor patients, the PTCy arm had better OS, and the mismatched unrelated donor group who received PTCy had similar OS as well. For GRFS, matched unrelated donor and mismatched unrelated donor PTCy patients had no difference in GRFS, similar to the trend the authors see with overall survival. But these patients also had better GRFS than matched unrelated donor patients receiving calcineurin inhibitor-based prophylaxis. Within each prophylaxis arm, there was no difference in GRFS by HLA matching status. HLA mismatched patients receiving PTCy were less likely to experience GRFS than HLA mismatched patients receiving calcineurin inhibitor-based prophylaxis. The authors saw similar differences in comparative trends when subgrouping patients based on conditioning intensity and additionally did not find differences in GRFS and OS by ATG exposure. When looking at patients with minority ancestry, those patients who received a match unrelated donor or mismatched unrelated donor with PTCy had comparable outcomes to non-Hispanic white patients. Additionally, among minority ancestry patients, there was a significant benefit in both GRFS and OS in the PTCy groups as compared to calcineurin inhibitor-based prophylaxis. When examining other specific toxicities included in the composite GRFS endpoint, such as GVHD rates among PTCy patients, the authors note that patients receiving a matched unrelated donor had similar rates of grade 3 to 4 acute GVHD but lower rates of moderate to severe chronic GVHD requiring systemic therapy. There appears to be signal that among PTCy patients, HLA matching reduced rates of moderate to severe chronic GVHD compared to mismatched unrelated donor patients receiving PTCy. These same trends also held when the authors looked at non relapse mortality with no significant differences within the PTCy groups by HLA matching status but reduced non relapse mortality compared to both calcineur and inhibitor-based groups. However, notably, there was a greater risk of relapse among matched unrelated donor PTCy patients than matched unrelated donor calcineurin inhibitor patients, although this risk was comparable between mismatched unrelated donor patients by type of prophylaxis. The authors note that this has also been observed in other retrospective cohorts and may be confounded by differences in conditioning intensity between these cohorts of matched unrelated donor patients, affecting the risk of relapse. Finally, the authors also evaluate whether expansion of donor search criteria to mismatch donors from full HLA matching would increase availability of young donors from minority ancestry patients, and the study noted striking increases for all subgroups examined. This study fits nicely with the BMT CTN 1703 trial published in the recent past, which has showed the superiority of PTCy with the calcineurin inhibitor and MMF when compared with conventional calcineurin inhibitor based immune prophylaxis for reduced intensity matched related donor and matched unrelated donor allotransplant. Of note, very few patients with one HLA antigen mismatch were enrolled on that study. However, others have shown the feasibility of PTCy in the mismatched unrelated donor setting, which has led to its adoption in practice. Although less than a quarter of patients included in this current study received PTCy overall, the findings clearly are aligned with the BMT CTN 1703 study, which is likely to change clinical practice in the longer term in this field. As the accompanying editorial in JCO, written by Dr. Chakravarty nicely lays out, the differences between this study and the EBMT registry study, also published in this issue of JCO are subtle but worthy of note. While both studies show that mismatched unrelated donor patients had worse OS and GRFS than those receiving matched unrelated donor transplants, and then among matched unrelated donor patients the addition of PTCy improved GRFS and OS, there is discordance between the studies whether the addition of PTCy abrogates the effect of HLA mismatching on GRFS and OS. As this editorial points out, there are strikingly different rates of T cell depletion with ATG between the US and Europe, which may account for differences in comparator arms that lead to this discordance. There are several very exciting clinical trials ongoing that will aim to answer some of these outstanding questions regarding comparisons of PTCy and T cell depletion, which the field eagerly looks forward to reviewing. In summary, this registry study of patients receiving allo transplant with matched unrelated donor or mismatched unrelated donor and calcineurin inhibitor or PTCy based GVHD prophylaxis, most notably shows that for patients who may not have a matched unrelated donor available, the addition of PTCy to a mismatched unrelated donor allo transplant allows for improved outcomes after transplant in toxicities and survival. This is most significant for patients of minority ancestries who usually have fewer matched unrelated donors available in registry searches. Improving the transplant options available to these groups of patients is of critical importance in improving equitable access to care for all of our patients. And this study, although retrospective in nature, provides an important understanding of our progress to date and suggests directions for future investigation may indeed be very feasible to continue to close these gaps in care for patients in need of an allo transplant for hematologic malignancies. This is Alexandra Rojek. Thank you for listening to JCO Article Insights. Don't forget to give us a rating or review, and be sure to subscribe so you never miss an episode. You can find all ASCO shows at asco.org/podcasts.   The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.    

This is the audio version of my YouTube video "From Unmatched to MATCHED into Residency | Reaction to Sarah Struble Match Experience". You can check the video version ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. If you need professional help with your residency application, check the MATCH Application Package ⁠here⁠. Get 20+ personal statement examples, ERAS Application Template, LOR, LOI, MSPE examples, and much more for FREE ⁠here⁠. Check my website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Check our blog ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Make sure to subscribe so you don't miss future episodes. If you got any value from this episode, please consider leaving a 5⭐rating! Feel free to reach out to me:

This hour, Mike Detillier, Herb Tyler and Lee Ann Herring (Director of recruiting at The Rebel Walk) preview the LSU Tigers vs. Ole Miss, and discuss the conclusion of Alabama vs. South Carolina.

Vice President Kamala Harris and former President Donald Trump are gearing up for Tuesday's debate, which comes after a new poll was released this weekend. The hunt continues for a man suspected of opening fire on the I-75 in Kentucky this weekend. The mother of the teenage school shooting suspect called to warn a school staff member before the attack. Tensions continue to escalate in the Middle East after reported Israeli airstrikes over the weekend in Lebanon and Syria. Plus, an NFL player celebrated a touchdown just hours after he was detained by the police. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Mark interviews Denise Massar, a writer, an adoptee, and a mom via birth and adoption about her new memoir MATCHED and the ten-year journey she took getting it published. Prior to the main content, Mark shares comments from a recent episode, a personal update, and a word from this episode's sponsor. This episode is sponsored by Cruising Writers. During their conversation Mark and Denise talk about: How Denise had been "big five or die" when it originally came to her publishing dream and how and why that changed over the years Some of the feedback that Denise's agent got back on submission of her memoir in 2020 and how they fueled her in a positive way Denise's agent coming up with a strategy to change the title, to wait a year as publishing shifts and movements within editorial departments would naturally occur, then to try to send it out on sub to the market again Some of the limitations within traditional publishing that happen with titles that might be perceived by some as "somewhat similar" How memoir from an "unknown" person is one of the hardest things to sell Prince Harry's penis Having run the course with her agent on this book, and the respectful mutual decision to part ways Submitting the book to a number of university presses without her agent The sudden health scare that turned out to be a benign lump that Denise had to have surgery to remove Resetting those initial big dreams that she had about what would happen when her book was finally published The importance of her kids seeing her "finish this book" that she'd been working on for 10 years Deciding to take the indie publishing approach which allowed her several freedoms, including changing the title back to MATCHED, working with the cover designer artist that she knew and liked, among other things Leveraging 60 different ARC readers for her memoir The power of hearing readers say things like "me too" - and "I never knew that anybody else went through that" and other ways a writer can come to feel that their writing resonates with readers Writing about her own adoption and realizing that for the first six months of her life, before she was adopted, that she must have been in foster care Altering the names of some of the people in the book in order to preserve their privacy How the eight different birth mothers Denise was in contact with via the course of adopting her son who ended up changing her life Advice Denise would give to her younger self as well as advise she'd give to beginning authors And more . . .   After the interview Mark reflects on just how significant it is when an editor provides any sort of feedback beyond a form/token "not for us at this time" rejection, as well as an agent that's willing to "re-package" a book in order to try to put it out on submission for a second round. He also reflects on how nothing can stop a determined writer.   Links of Interest: Denise Massar's Website Denise on Instagram Mark's Kickstarter for ONE HAND SCREAMING: 20 Haunting Years EP 188 - A Gritty & Real Adoption and Publishing Journey with Denise Massar Mark's Stark Reflections on Writing & Publishing Newsletter (Signup) Cruising Writers Buy Mark a Coffee Patreon for Stark Reflections How to Access Patreon RSS Feeds An Author's Guide to Working With Bookstores and Libraries The Relaxed Author Buy eBook Direct Buy Audiobook Direct Publishing Pitfalls for Authors An Author's Guide to Working with Libraries & Bookstores Wide for the Win Mark's Canadian Werewolf Books This Time Around (Short Story) A Canadian Werewolf in New York Stowe Away (Novella) Fear and Longing in Los Angeles Fright Nights, Big City Lover's Moon Hex and the City Only Monsters in the Building The Canadian Mounted: A Trivia Guide to Planes, Trains and Automobiles Yippee Ki-Yay Motherf*cker: A Trivia Guide to Die Hard   Denise Massar is a writer, an adoptee, and a mom via birth and adoption. Her essays have been published in HuffPost, Writer's Digest, Mutha Magazine, Raise Magazine, An Injustice!, and she's a recurring guest blogger for Jane Friedman. Denise's memoir, Matched, is about the nine months she spent obsessively searching for a baby to adopt, the nine potential birth moms she met on that journey, and how, in a twist of fate, her son's birth mom led Denise to the one person she thought she'd never meet: The woman who gave birth to her. You can find Matched anywhere you buy books, and you can read the first ten pages right now, and get Denise's Top Ten Memoir Recommendations on her website, http://www.denisemassar.org/   The introductory, end, and bumper music for this podcast (“Laser Groove”) was composed and produced by Kevin MacLeod of www.incompetech.com and is Licensed under Creative Commons: By Attribution 3.0

Today was an amazing first! We did an author interview with Cassie from Unfortunate Reads and Vera Valentine to discuss Pushin' Cushions? They're absolutely amazing and a blast to chat with. We can't wait for you guys to read this and their other works. We want you to know that Cassie and friends are doing a charity anthology to support ProLiteracy and you can purchase it here, Matched by the Unicorn: An Unusual Charity Anthology. If you're into sentient object recs you can get them all here: Sentient Object Romance

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In this episode we answer emails from Judy, Steve and MyContactInfo.   We discuss a recent offer by The Financial Quarterback podcast to match donations the the Father McKenna Center (yay!), why you should buy gold ETFs and NOT physical gold, Cartman and Kyle, and the varying value of education depending on the individual.Links:Father McKenna Center Donation Page -- Remember to mention "The Financial Quarterback match" in new donations:  Donate - Father McKenna CenterETF Database -- Gold ETFs:  Gold ETF List (etfdb.com)Listener John's Gold ETF link:  9 low cost physical Gold ETFs for portfolio parity - SmartMoneyToolboxGLD FAQs:  FAQs > USA > SPDR Gold Shares (GLD). Bringing the gold market to investorsSupport the Show.

PREVIEW: #NORMANDY: #SHERMAN TANK: Comment by author James Holland for his book BROTHERS IN ARMS, re the British Army tank regiment, Sherwood Rangers -- and here how their Sherman tanks matched against the monstrously larger German Tigers and Panzers.  More tonight. 1945 Rhine River

First, a tribute to the wonderful student protesters at UC Davis in California!  Next, Katie shares the details of her weekend spent with a bunch of single 20-somethings! See omnystudio.com/listener for privacy information.