Podcasts about picower institute

Revive nuestro primer evento en vivo de Mi Última Neurona, realizado el pasado 25 de septiembre en el MIT Museum, como parte del Cambridge Science Festival.

A new potential Alzheimer's therapy uses 40-hertz frequencies of light and sound to stimulate the brain. Research applying this treatment to mice showed a substantial decrease in amyloid plaques, a key biomarker for the disease, and an improvement in cognitive function. Clinical trials testing the efficacy of this method in humans are underway.But how exactly does this treatment work? Could it be a game changer in Alzheimer's patients? And what potential does it have for other degenerative diseases, like multiple sclerosis?Ira talks with Dr. Li-Huei Tsai, professor of neuroscience and director of Picower Institute for Learning and Memory at the Massachusetts Institute of Technology, about her work developing this therapy.Transcript for this segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Send us a Text Message.Experience a 40Hz stress relief with "Stress Less," a cognitive fitness vibe crafted by Victoria Deiorio, Vibes AI's Chief Vibroacoustic Designer.Learn More About 40Hz Science-backed Cognitive Health Benefits  [1] [2] [3] [4] [5] [6]Boost Cognitive FunctionReduce Alzheimer's PathologyEnhance Sleep QualityDecrease Stress and AnxietyImprove Focus and Concentration[1] Sharpe RLS, Mahmud M, Kaiser MS, Chen J. Gamma entertainment frequency affects mood, memory and cognition: an exploratory pilot study. Brain Inform. 2020;7(1):17. doi: 10.1186/s40708-020-00119-9[2] WebMD. (n.d.). What to know about gamma brain waves. WebMD. https://www.webmd.com/brain/what-to-know-about-gamma-brain-waves[3] Guan A, Wang S, Huang, A, Qiu C, Li Y, Li X, Wang J, Wang Q, Deng B. The role of gamma oscillations in central nervous system diseases: Mechanism and treatment. Front Cell Neurosci. 2022;16:962957. doi: 10.3389/fncel.2022.962957[4] Picower Institute at MIT. 2024. How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice. ScienceDaily. https://www.sciencedaily.com/releases/2024/02/240228114328.htm[5] Healthcare (Basel). 2023 Jul; 11(14): 2040. A Feasibility Study of AlzLife 40 Hz Sensory Therapy in Patients with MCI and Early AD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379682/ [6] Brain Inform. 2020 Dec; 7(1): 17. Gamma entrainment frequency affects mood, memory and cognition: an exploratory pilot study   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683678/ Support the Show.At Vibes AI, we believe that all humans are capable of super intelligence. That is why we have embarked on a journey to create a new generation of smart technologies that seamlessly fit into your life, enabling you to conveniently make your brain's vitality a priority. Learn MoreListen on your favorite podcasting services

Send us a Text Message.Strengthen your cognitive function & focus with a 40Hz cognitive fitness vibe called Focus Fusion.Learn More About 40Hz Science-backed Cognitive Health Benefits  [1] [2] [3] [4] [5] [6]Boost Cognitive FunctionReduce Alzheimer's PathologyEnhance Sleep QualityDecrease Stress and AnxietyImprove Focus and Concentration[1] Sharpe RLS, Mahmud M, Kaiser MS, Chen J. Gamma entertainment frequency affects mood, memory and cognition: an exploratory pilot study. Brain Inform. 2020;7(1):17. doi: 10.1186/s40708-020-00119-9[2] WebMD. (n.d.). What to know about gamma brain waves. WebMD. https://www.webmd.com/brain/what-to-know-about-gamma-brain-waves[3] Guan A, Wang S, Huang, A, Qiu C, Li Y, Li X, Wang J, Wang Q, Deng B. The role of gamma oscillations in central nervous system diseases: Mechanism and treatment. Front Cell Neurosci. 2022;16:962957. doi: 10.3389/fncel.2022.962957[4] Picower Institute at MIT. 2024. How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice. ScienceDaily. https://www.sciencedaily.com/releases/2024/02/240228114328.htm[5] Healthcare (Basel). 2023 Jul; 11(14): 2040. A Feasibility Study of AlzLife 40 Hz Sensory Therapy in Patients with MCI and Early AD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379682/ [6] Brain Inform. 2020 Dec; 7(1): 17. Gamma entrainment frequency affects mood, memory and cognition: an exploratory pilot study   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683678/ Support the Show.At Vibes AI, we believe that all humans are capable of super intelligence. That is why we have embarked on a journey to create a new generation of smart technologies that seamlessly fit into your life, enabling you to conveniently make your brain's vitality a priority. Learn MoreListen on your favorite podcasting services

Send us a Text Message.Embark on a 5 min 40Hz journey of boundless creativity with "Creative Flow," an innovative cognitive fitness vibe expertly crafted by Victoria Deiorio, Vibes AI's Chief Vibroacoustic Designer. Learn More About 40Hz Science-backed Cognitive Health Benefits  [1] [2] [3] [4] [5] [6]Boost Cognitive FunctionReduce Alzheimer's PathologyEnhance Sleep QualityDecrease Stress and AnxietyImprove Focus and Concentration[1] Sharpe RLS, Mahmud M, Kaiser MS, Chen J. Gamma entertainment frequency affects mood, memory and cognition: an exploratory pilot study. Brain Inform. 2020;7(1):17. doi: 10.1186/s40708-020-00119-9[2] WebMD. (n.d.). What to know about gamma brain waves. WebMD. https://www.webmd.com/brain/what-to-know-about-gamma-brain-waves[3] Guan A, Wang S, Huang, A, Qiu C, Li Y, Li X, Wang J, Wang Q, Deng B. The role of gamma oscillations in central nervous system diseases: Mechanism and treatment. Front Cell Neurosci. 2022;16:962957. doi: 10.3389/fncel.2022.962957[4] Picower Institute at MIT. 2024. How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice. ScienceDaily. https://www.sciencedaily.com/releases/2024/02/240228114328.htm[5] Healthcare (Basel). 2023 Jul; 11(14): 2040. A Feasibility Study of AlzLife 40 Hz Sensory Therapy in Patients with MCI and Early AD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379682/ [6] Brain Inform. 2020 Dec; 7(1): 17. Gamma entrainment frequency affects mood, memory and cognition: an exploratory pilot study   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683678/ Support the Show.At Vibes AI, we believe that all humans are capable of super intelligence. That is why we have embarked on a journey to create a new generation of smart technologies that seamlessly fit into your life, enabling you to conveniently make your brain's vitality a priority. Learn MoreListen on your favorite podcasting services

Subscriber-only episodeSend us a Text Message.Embark on a 5 min 40Hz journey of boundless creativity with "Creative Flow," an innovative cognitive fitness vibe expertly crafted by Victoria Deiorio, Vibes AI's Chief Vibroacoustic Designer.Learn More About 40Hz Science-backed Cognitive Health Benefits  [1] [2] [3] [4] [5] [6]Boost Cognitive FunctionReduce Alzheimer's PathologyEnhance Sleep QualityDecrease Stress and AnxietyImprove Focus and Concentration[1] Sharpe RLS, Mahmud M, Kaiser MS, Chen J. Gamma entertainment frequency affects mood, memory and cognition: an exploratory pilot study. Brain Inform. 2020;7(1):17. doi: 10.1186/s40708-020-00119-9[2] WebMD. (n.d.). What to know about gamma brain waves. WebMD. https://www.webmd.com/brain/what-to-know-about-gamma-brain-waves[3] Guan A, Wang S, Huang, A, Qiu C, Li Y, Li X, Wang J, Wang Q, Deng B. The role of gamma oscillations in central nervous system diseases: Mechanism and treatment. Front Cell Neurosci. 2022;16:962957. doi: 10.3389/fncel.2022.962957[4] Picower Institute at MIT. 2024. How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice. ScienceDaily. https://www.sciencedaily.com/releases/2024/02/240228114328.htm[5] Healthcare (Basel). 2023 Jul; 11(14): 2040. A Feasibility Study of AlzLife 40 Hz Sensory Therapy in Patients with MCI and Early AD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379682/ [6] Brain Inform. 2020 Dec; 7(1): 17. Gamma entrainment frequency affects mood, memory and cognition: an exploratory pilot study   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683678/ At Vibes AI, we believe that all humans are capable of super intelligence. That is why we have embarked on a journey to create a new generation of smart technologies that seamlessly fit into your life, enabling you to conveniently make your brain's vitality a priority. Learn MoreListen on your favorite podcasting services

Subscriber-only episodeSend us a Text Message.Strengthen your cognitive function & focus with a 60 min, 40Hz cognitive wellness vibe called Focus Fusion.Learn More About 40Hz Science-backed Cognitive Health Benefits [1][2][3][4][5][6]Boost Cognitive FunctionReduce Alzheimer's PathologyEnhance Sleep QualityDecrease Stress and AnxietyImprove Focus and Concentration[1] Sharpe RLS, Mahmud M, Kaiser MS, Chen J. Gamma entertainment frequency affects mood, memory and cognition: an exploratory pilot study. Brain Inform. 2020;7(1):17. doi: 10.1186/s40708-020-00119-9[2] WebMD. (n.d.). What to know about gamma brain waves. WebMD. https://www.webmd.com/brain/what-to-know-about-gamma-brain-waves[3] Guan A, Wang S, Huang, A, Qiu C, Li Y, Li X, Wang J, Wang Q, Deng B. The role of gamma oscillations in central nervous system diseases: Mechanism and treatment. Front Cell Neurosci. 2022;16:962957. doi: 10.3389/fncel.2022.962957[4] Picower Institute at MIT. 2024. How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice. ScienceDaily. https://www.sciencedaily.com/releases/2024/02/240228114328.htm[5] Healthcare (Basel). 2023 Jul; 11(14): 2040. A Feasibility Study of AlzLife 40 Hz Sensory Therapy in Patients with MCI and Early AD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379682/ [6] Brain Inform. 2020 Dec; 7(1): 17. Gamma entrainment frequency affects mood, memory and cognition: an exploratory pilot study   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683678/ At Vibes AI, we believe that all humans are capable of super intelligence. That is why we have embarked on a journey to create a new generation of smart technologies that seamlessly fit into your life, enabling you to conveniently make your brain's vitality a priority. Learn MoreListen on your favorite podcasting services

Subscriber-only episodeSend us a Text Message.Experience a 60 min, 40Hz stress relief with "Stress Less," a cognitive fitness vibe crafted by Victoria Deiorio, Vibes AI's Chief Vibroacoustic Designer.Learn More About 40Hz Science-backed Cognitive Health Benefits [1][2][3][4][5][6]Boost Cognitive FunctionReduce Alzheimer's PathologyEnhance Sleep QualityDecrease Stress and AnxietyImprove Focus and Concentration[1] Sharpe RLS, Mahmud M, Kaiser MS, Chen J. Gamma entertainment frequency affects mood, memory and cognition: an exploratory pilot study. Brain Inform. 2020;7(1):17. doi: 10.1186/s40708-020-00119-9[2] WebMD. (n.d.). What to know about gamma brain waves. WebMD. https://www.webmd.com/brain/what-to-know-about-gamma-brain-waves[3] Guan A, Wang S, Huang, A, Qiu C, Li Y, Li X, Wang J, Wang Q, Deng B. The role of gamma oscillations in central nervous system diseases: Mechanism and treatment. Front Cell Neurosci. 2022;16:962957. doi: 10.3389/fncel.2022.962957[4] Picower Institute at MIT. 2024. How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice. ScienceDaily. https://www.sciencedaily.com/releases/2024/02/240228114328.htm[5] Healthcare (Basel). 2023 Jul; 11(14): 2040. A Feasibility Study of AlzLife 40 Hz Sensory Therapy in Patients with MCI and Early AD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379682/ [6] Brain Inform. 2020 Dec; 7(1): 17. Gamma entrainment frequency affects mood, memory and cognition: an exploratory pilot study   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683678/ At Vibes AI, we believe that all humans are capable of super intelligence. That is why we have embarked on a journey to create a new generation of smart technologies that seamlessly fit into your life, enabling you to conveniently make your brain's vitality a priority. Learn MoreListen on your favorite podcasting services

Please join The Commonwealth Club for an evening with the leaders of the Buck Institute, one of the country's leading research organizations on aging. We'll hear from the leader of the Buck Institute on "Healthspan," then enjoy an in-person wine and cheese reception. "Healthspan" is the period of life in which an individual is healthy and free from chronic disease. Interventions that promote healthy aging, such as diet and exercise, can help increase healthspan and reduce the burden of age-related diseases. Dr. Eric Verdin will discuss his efforts and those of his colleagues at the Buck Institute in helping to advance our understanding of aging and develop new strategies for promoting healthy aging and extending healthspan. Eric Verdin, MD, is the president and CEO of the Buck Institute for Research on Aging, a pioneering biomedical research institute dedicated to aging and age-related disease. A native of Belgium, Dr. Verdin received his Doctorate of Medicine from the University of Liege and completed additional clinical and research training at Harvard Medical School. He has held faculty positions at the University of Brussels, the National Institutes of Health, and the Picower Institute for Learning and Memory. Dr. Verdin is also currently a professor of medicine at the University of California, San Francisco. In 2016 Dr. Verdin established his laboratory at the Buck Institute for Research on Aging to study the relationship between aging and the immune system. He is an elected member of several scientific organizations, including the American Association for the Advancement of Science, the American Society for Clinical Investigation, and the Association of American Physicians. He also serves on the advisory council of the National Institute on Drug Abuse at the National Institutes of Health. There will be a post-program reception for all attendees. Learn more about your ad choices. Visit megaphone.fm/adchoices

“There are a lot of distractions in cities. So it's always good to maybe take some time out, be in a quieter place with no distractions so you can let your thoughts run. And that leads into the creative process because new ideas, new thoughts and where they come from. They come from following the garden path of associations in your mind. One thought leads to another, leads to another until your mind is in a new place it's never been before. Or you put two thoughts together that were never together before, but now they are because you managed to somehow follow this garden path of thoughts from one thought to the other. That's where creativity comes from, that's where your ideas come from, seeing things in a new way, seeing things that were never together before. And if you have constant distractions that interferes with that process.”Earl K. Miller is the Picower Professor of Neuroscience in the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology. Miller studies the neural basis of executive control, the ability to carry out goal-directed behavior using complex mental processes and cognitive abilities. This work has established a foundation upon which to construct more detailed, mechanistic accounts of cognition and its dysfunction in diseases such as autism, schizophrenia and attention deficit disorder. He's the recipient of a variety of awards and his paper with Jonathan Cohen which presented a new framework for understanding the prefrontal cortex, ranks fifth all-time in citations in neuroscience.· ekmillerlab.mit.edu · www.creativeprocess.info

“There are a lot of distractions in cities. So it's always good to maybe take some time out, be in a quieter place with no distractions so you can let your thoughts run. And that leads into the creative process because new ideas, new thoughts and where they come from. They come from following the garden path of associations in your mind. One thought leads to another, leads to another until your mind is in a new place it's never been before. Or you put two thoughts together that were never together before, but now they are because you managed to somehow follow this garden path of thoughts from one thought to the other. That's where creativity comes from, that's where your ideas come from, seeing things in a new way, seeing things that were never together before. And if you have constant distractions that interferes with that process.”Earl K. Miller is the Picower Professor of Neuroscience in the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology. Miller studies the neural basis of executive control, the ability to carry out goal-directed behavior using complex mental processes and cognitive abilities. This work has established a foundation upon which to construct more detailed, mechanistic accounts of cognition and its dysfunction in diseases such as autism, schizophrenia and attention deficit disorder. He's the recipient of a variety of awards and his paper with Jonathan Cohen which presented a new framework for understanding the prefrontal cortex, ranks fifth all-time in citations in neuroscience.· ekmillerlab.mit.edu · www.creativeprocess.info

Earl K. Miller is the Picower Professor of Neuroscience in the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology. Miller studies the neural basis of executive control, the ability to carry out goal-directed behavior using complex mental processes and cognitive abilities. This work has established a foundation upon which to construct more detailed, mechanistic accounts of cognition and its dysfunction in diseases such as autism, schizophrenia and attention deficit disorder. He's the recipient of a variety of awards and his paper with Jonathan Cohen which presented a new framework for understanding the prefrontal cortex, ranks fifth all-time in citations in neuroscience.· ekmillerlab.mit.edu · www.creativeprocess.info

“There are a lot of distractions in cities. So it's always good to maybe take some time out, be in a quieter place with no distractions so you can let your thoughts run. And that leads into the creative process because new ideas, new thoughts and where they come from. They come from following the garden path of associations in your mind. One thought leads to another, leads to another until your mind is in a new place it's never been before. Or you put two thoughts together that were never together before, but now they are because you managed to somehow follow this garden path of thoughts from one thought to the other. That's where creativity comes from, that's where your ideas come from, seeing things in a new way, seeing things that were never together before. And if you have constant distractions that interferes with that process.”Earl K. Miller is the Picower Professor of Neuroscience in the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology. Miller studies the neural basis of executive control, the ability to carry out goal-directed behavior using complex mental processes and cognitive abilities. This work has established a foundation upon which to construct more detailed, mechanistic accounts of cognition and its dysfunction in diseases such as autism, schizophrenia and attention deficit disorder. He's the recipient of a variety of awards and his paper with Jonathan Cohen which presented a new framework for understanding the prefrontal cortex, ranks fifth all-time in citations in neuroscience.· ekmillerlab.mit.edu · www.creativeprocess.info

Earl K. Miller is the Picower Professor of Neuroscience in the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology. Miller studies the neural basis of executive control, the ability to carry out goal-directed behavior using complex mental processes and cognitive abilities. This work has established a foundation upon which to construct more detailed, mechanistic accounts of cognition and its dysfunction in diseases such as autism, schizophrenia and attention deficit disorder. He's the recipient of a variety of awards and his paper with Jonathan Cohen which presented a new framework for understanding the prefrontal cortex, ranks fifth all-time in citations in neuroscience.· ekmillerlab.mit.edu · www.creativeprocess.info

Earl K. Miller is the Picower Professor of Neuroscience in the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology. Miller studies the neural basis of executive control, the ability to carry out goal-directed behavior using complex mental processes and cognitive abilities. This work has established a foundation upon which to construct more detailed, mechanistic accounts of cognition and its dysfunction in diseases such as autism, schizophrenia and attention deficit disorder. He's the recipient of a variety of awards and his paper with Jonathan Cohen which presented a new framework for understanding the prefrontal cortex, ranks fifth all-time in citations in neuroscience.· ekmillerlab.mit.edu · www.creativeprocess.info

“There are a lot of distractions in cities. So it's always good to maybe take some time out, be in a quieter place with no distractions so you can let your thoughts run. And that leads into the creative process because new ideas, new thoughts and where they come from. They come from following the garden path of associations in your mind. One thought leads to another, leads to another until your mind is in a new place it's never been before. Or you put two thoughts together that were never together before, but now they are because you managed to somehow follow this garden path of thoughts from one thought to the other. That's where creativity comes from, that's where your ideas come from, seeing things in a new way, seeing things that were never together before. And if you have constant distractions that interferes with that process.”Earl K. Miller is the Picower Professor of Neuroscience in the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology. Miller studies the neural basis of executive control, the ability to carry out goal-directed behavior using complex mental processes and cognitive abilities. This work has established a foundation upon which to construct more detailed, mechanistic accounts of cognition and its dysfunction in diseases such as autism, schizophrenia and attention deficit disorder. He's the recipient of a variety of awards and his paper with Jonathan Cohen which presented a new framework for understanding the prefrontal cortex, ranks fifth all-time in citations in neuroscience.· ekmillerlab.mit.edu · www.creativeprocess.info

Episode Notes On this episode, SunAh talks with Dr. Héctor de Jesús-Cortés, Postdoctoral Fellow in the Picower Institute for Learning and Memory at Massachusetts Institute of Technology and the Director of the Sagrado-MIT Neuroscience Pre-college Program. He shares his research on neuropsychiatric disorders and possible interventions as well as the rather happenstance way he became interested in neuroscience. If you'd like to learn more about the research Dr. de Jesús-Cortés's shared in this episode, he can be reached via email at hdejesus@mit.edu

Dr. Eric Verdin, MD (https://www.buckinstitute.org/lab/verdin-lab/) is President and Chief Executive Officer of the Buck Institute for Research on Aging, as well as Professor of Medicine at University of California, San Francisco (https://bms.ucsf.edu/people/eric-verdin-md). Dr. Verdin's lab currently studies the relationship between aging and the immune system per associated defects in the adaptive immune system, and over chronic activation of the innate immune system, as well as programs on how metabolism, diet, and small molecules regulate the activity of histone deacetylases and sirtuins, and thereby the aging process and its associated diseases, including Alzheimer's. Dr. Verdin has published more than 200 scientific papers and holds more than 15 patents. He is a highly cited scientist (top 1 percent) and has been recognized for his research with a Glenn Award for Research in Biological Mechanisms of Aging and a senior scholarship from the Ellison Medical Foundation. Dr. Verdin is an elected member of several scientific organizations, including the American Association for the Advancement of Science, the American Society for Clinical Investigation, and the Association of American Physicians. He also serves on the advisory council of National Institute on Drug Abuse at the National Institutes of Health. Dr. Verdin has extensive experience working with biotech companies. He is a founder of Acylin (purchased by Abbvie). He served on the scientific advisory boards of Elixir, Sirtris (purchased by GSK), Calico (Google), and Nokia, and he also served as advisor to Sofinnova Ventures. Dr. Verdin has also worked for several years as a consultant to Novartis, GSK, J&J, Altana, Roche, Pfizer, and other biotech companies. Dr. Verdin received his Doctorate of Medicine (MD) from the University of Liege, completed additional clinical and research training at Harvard Medical School, and has held faculty positions at the University of Brussels, the National Institutes of Health (NIH), and the Picower Institute for Medical Research.

Pathophysiology and correction of amblyopia, The synaptic substrates of visual recognition memory, and pathophysiology and correction of fragile X syndrome and other causes of autism Prof. Mark Bear is a Professor of Neuroscience in The Picower Institute for Learning and Memory and the Department of Brain and Cognitive Sciences at Massachusetts Institute of Technology. His laboratory is interested in how the brain is modified by experience. He uses a variety of methods to examine the synaptic modifications that form the neurobiological basis of learning and memory. --- Send in a voice message: https://anchor.fm/scientificsense/message Support this podcast: https://anchor.fm/scientificsense/support

Neuroscientist and Science Communicator Shruti Muralidhar is on Episode 145 of The Pragati Podcast to talk about the challenges of science publishing and science communication in 2020. Shruti also talks to host Pavan Srinath about how Scicomm can be transformed in India.Announcement: The Pragati Podcast will now be releasing new episodes every Thursday morning, India time. The Pragati Podcast is also now available in a new rich and interactive format that goes beyond the audio, and enables listeners to explore contextual links, take polls, and more. Listen to this episode on the IVM Podcasts Android App at https://ivm.today/android , Adori IOS app at tinyurl.com/adoriapp , or listen in on your browser at tinyurl.com/pragati145 for the full experience.Shruti Muralidhar (@polybiotique) is a neuroscientist and science communicator. By day, Shruti works on learning and memory as a postdoctoral researcher at the Picower Institute at MIT. She is a founding member of IndSciComm along with Abhishek Chari, and IndSciComm is a collective formed to improve scientific awareness in India and help Indian researchers interact with the public. Learn more at https://indscicomm.blog/Read Shruti's policy memo outlining urgent points of action to improve science communication in India: https://indscicomm.blog/2020/07/12/scicomm-policy-memo-for-stip-2020/Follow The Pragati Podcast on Instagram: https://instagram.com/pragatipod &Follow Pragati on Twitter: https://twitter.com/thinkpragati &Follow Pragati on Facebook: https://facebook.com/thinkpragatiThe Pragati Podcast is made possible thanks to the support of The Takshashila Institution and the Independent Public-Spirited Media Foundation (IPSMF).

Can flickering LED lights really cure Alzheimer’s disease? In our first episode, we will explore the 40Hz idea with Dr. Li-Huei Tsai. Dr. Tsai is the Director of the Picower Institute for Learning and Memory, a Professor of Neuroscience at the Department of Brain and Cognitive Sciences at MIT, and a Senior Associate Member of the Broad Institute.

In the second part of this epic podcast, Andy and Dave continue their discussion with research from MIT, Vienna University of Technology, and Boston University, which uses human brainwaves and hand gestures to instantly correct robot mistakes. The research uses a combination of electroencephalogram (EEG, brain signals) and electromyogram (EMG, muscle signals) in combination to allow a human (without training) to provide corrective input to a robot while it performs tasks. On a related topic, MIT’s Picower Institute for Learning and Memory demonstrated the rules for human brain plasticity, by showing that when one synapse connection strengthens, the immediately neighboring synapses weaken; while suspected for some time, this research showed for the first time how this balance works. Then, research from Stanford and Berkley introduces a Taskonomy, a system for disentangling task transfer learning. This structured approach maps out 25 different visual tasks to identify the conditions under which transfer learning works from one task to another; such a structure would allow data in some dimensions to compensate for the lack of data in other dimensions. Next up, OpenAI has developed an AI tool for spotting photoshopped photos, by examining three types of manipulation techniques (splicing, copy-move, and removal), and by also examining local noise features. Researchers at Stanford have used machine learning to recreate the periodic table of elements after providing the system with a database of chemical formulae. And finally, Andy and Dave wrap up with a selection of papers and other media, including CNAS’s AI: What Every Policymaker Needs to Know; a beautifully-done tutorial on machine learning; the Question for AI by Nilsson; Nonserviam by Lem; IPI’s Governing AI; the US Congressional Hearing on the Power of AI; and Twitch Plays Robotics.

Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF. Dr. Verdin's laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabolism and diet in aging and on the chronic diseases of aging, including Alzheimer’s, proteins that play a central role in linking caloric restriction to increased healthspan, and more recently a topic near and dear to many of you, ketogenesis. He's held faculty positions at the University of Brussels, the NIH and the Picower Institute for Medical Research. In this episode, we discuss... The effects of a low protein, cyclic ketogenic diet beginning in midlife (12 months of age) in male mice. The result? Increased healthspan and improved memory. Dr. Verdin explains how the cyclic ketogenic diet decreased insulin, IGF-1, and mTOR signaling and decreased fatty acid synthesis, and increased PPAR-alpha (which promotes beta-oxidation and mitochondrial biogenesis in muscle). How this diet is somewhat qualitatively similar to fasting. Some of the possible reasons why the cyclic ketogenic diet created such a striking improvement in memory even when compared to younger mice. How beta-hydroxybutyrate, which is the major circulating ketone body during fasting and nutritional ketosis, may, in addition to being an energy source, regulate inflammation and gene expression by acting as a signaling molecule by inhibiting what are known as class 1 histone deacetylases (HDACs). How this inhibition of class 1 HDACs leads to the increased expression of notorious longevity gene Foxo3, which may help explain why mice given an exogenous beta-hydroxybutyrate ester had lower markers of inflammation and oxidative damage, which are physiological contributors to the aging process. The role of the nicotinamide adenine dinucleotide (NAD+) in the aging process and how replacing declining levels (or preventing them from declining in the first place) may prove to be an important anti-aging strategy. Some of the reasons why NAD+ might be declining with age, its role in DNA damage repair via an enzyme known as PARP, and what the literature says about the NAD+ precursor nicotinamide riboside. How a special class of enzymes called sirtuins, also known to be activated by caloric restriction and caloric restriction mimetic resveratrol, is tightly correlated with the level of NAD+ and how this "energetic currency" rises in response to fasting. The role of the sirtuin enzymes in regulating mitochondrial function, neuronal functions, stem cell rejuvenation and why they may be important in delaying the aging process. Grab the full show notes, timeline & glossary from the episode page now. Did you enjoy this podcast? It was brought to you by people like you! Click here to visit our crowdsponsor page where you can learn more about how you can support the podcast for as little or as much as you like.

Eric M. Verdin Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF. Dr. Verdin's laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabolism and diet in aging and on the chronic diseases of aging, including Alzheimer's, proteins that play a central role in linking caloric restriction to increased healthspan, and more recently a topic near and dear to many of you, ketogenesis. He's held faculty positions at the University of Brussels, the NIH and the Picower Institute for Medical Research.  In this episode, you'll discover: The effects of a low protein, cyclic ketogenic diet beginning in midlife (12 months of age) in male mice. The result? Increased healthspan and improved memory. Dr. Verdin explains how the cyclic ketogenic diet decreased insulin, IGF-1, and mTOR signaling and decreased fatty acid synthesis, and increased PPAR-alpha (which promotes beta-oxidation and mitochondrial biogenesis in muscle). How this diet is somewhat qualitatively similar to fasting. Some of the possible reasons why the cyclic ketogenic diet created such a striking improvement in memory even when compared to younger mice. How beta-hydroxybutyrate, which is the major circulating ketone body during fasting and nutritional ketosis, may, in addition to being an energy source, regulate inflammation and gene expression by acting as a signaling molecule by inhibiting what are known as class 1 histone deacetylases (HDACs). How this inhibition of class 1 HDACs leads to the increased expression of notorious longevity gene Foxo3, which may help explain why mice given an exogenous beta-hydroxybutyrate ester had lower markers of inflammation and oxidative damage, which are physiological contributors to the aging process. The role of the nicotinamide adenine dinucleotide (NAD+) in the aging process and how replacing declining levels (or preventing them from declining in the first place) may prove to be an important anti-aging strategy. Some of the reasons why NAD+ might be declining with age, its role in DNA damage repair via an enzyme known as PARP, and what the literature says about the NAD+ precursor nicotinamide riboside. How a special class of enzymes called sirtuins, also known to be activated by caloric restriction and caloric restriction mimetic resveratrol, is tightly correlated with the level of NAD+ and how this "energetic currency" rises in response to fasting. The role of the sirtuin enzymes in regulating mitochondrial function, neuronal functions, stem cell rejuvenation and why they may be important in delaying the aging process.   If you're interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/69 Join over 300,000 people and get the latest distilled information on ketogenic diet & longevity straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

I recently spoke to Matt Cooney at NICKERSON PR about the development of Virtual and Augmented Reality.  We charted the differences and Matt made predictions about the future of this technology on a variety of industries and businesses including real estate.  This is fascinating stuff and vital as we try to understand where the trends in economic growth and employment are going. Forming and engaging communities has been the common thread in Matthew Cooney's career path. He has built and scaled social media communities for organizations including the Picower Institute for Learning and Memory at M.I.T., iRobot, and Monster. Prior to joining NICKERSON, an award-winning full service marketing and communications agency, as Director of Social Media and Emerging Technologies, he served as a subject matter expert on virtual reality technology at Dell EMC. Today, he works at the intersection of real estate and emerging technologies, witnessing firsthand how virtual and augmented reality technologies are disrupting social media and the way we live and interact in both the real and digital worlds. Samantha Wolfe provides quick definition of Virtual and Augmented Reality HERE and a list of the typical tools and interface points HERE QUESTIONS - How did you get started in the technology space? - VR versus AR: what they are/what's the difference? - What are practical applications for both? - How are they being used?  Entertainment, Education, Enhancement -How can these technological concepts be developed? -Who are the major players? -Where are the hotbeds of innovation? -What are the hurdles to adoption? -Technological limitations? -Ethical concerns? -Are there multiple approaches to the same problem? -What are the security concerns? -How does this intersect with the major leaps made recently with Artificial Intelligence?  “Big Data”? -How does this intersect with the advances made in robotics and exoskeleton/cybernetic technology? -What does the future hold, both near term and within the next five years, and beyond? -What is exciting in space? -What is worrisome? -What industries are are in the crosshairs? -What will the impact be on social media? -Specifically, how we consume and share content, and congregate and interact online? -How do we keep up to date on NICKERSON and what you are working on?

I recently spoke to Matt Cooney at NICKERSON PR about the development of Virtual and Augmented Reality.  We charted the differences and Matt made predictions about the future of this technology on a variety of industries and businesses including real estate.  This is fascinating stuff and vital as we try to understand where the trends in economic growth and employment are going. Forming and engaging communities has been the common thread in Matthew Cooney's career path. He has built and scaled social media communities for organizations including the Picower Institute for Learning and Memory at M.I.T., iRobot, and Monster. Prior to joining NICKERSON, an award-winning full service marketing and communications agency, as Director of Social Media and Emerging Technologies, he served as a subject matter expert on virtual reality technology at Dell EMC. Today, he works at the intersection of real estate and emerging technologies, witnessing firsthand how virtual and augmented reality technologies are disrupting social media and the way we live and interact in both the real and digital worlds. Samantha Wolfe provides quick definition of Virtual and Augmented Reality HERE and a list of the typical tools and interface points HERE QUESTIONS - How did you get started in the technology space? - VR versus AR: what they are/what's the difference? - What are practical applications for both? - How are they being used?  Entertainment, Education, Enhancement -How can these technological concepts be developed? -Who are the major players? -Where are the hotbeds of innovation? -What are the hurdles to adoption? -Technological limitations? -Ethical concerns? -Are there multiple approaches to the same problem? -What are the security concerns? -How does this intersect with the major leaps made recently with Artificial Intelligence?  “Big Data”? -How does this intersect with the advances made in robotics and exoskeleton/cybernetic technology? -What does the future hold, both near term and within the next five years, and beyond? -What is exciting in space? -What is worrisome? -What industries are are in the crosshairs? -What will the impact be on social media? -Specifically, how we consume and share content, and congregate and interact online? -How do we keep up to date on NICKERSON and what you are working on?

Dr. Kay Tye is an Assistant Professor of Neuroscience in the Department of Brain and Cognitive Sciences and Picower Institute for Learning and Memory at the Massachusetts Institute of Technology. She received her undergraduate degree from MIT in Brain and Cognitive Sciences and her PhD in Neuroscience from the University of California, San Francisco. Afterward Kay conducted postdoctoral research at Stanford University before joining the faculty at MIT. Kay has received many awards and honors during her career, including the National Alliance for Research on Schizophrenia and Depression Young Investigator Award, the NIH Director’s New Innovator Award, and the MIT Whitehead Career Development Professorship, New York Stem Cell Foundation Robertson Investigator Award, and has just been named a McKnight Scholar, just to name a few. Kay is with us today to tell us all about her journey through life and science.

This week on Neurotalk, we chat with Li-Huei Tsai about her transition from cancer research to neuroscience, chromatin remodeling, Alzheimer's disease, and more! Dr. Tsai is a professor of neuroscience and the director of the Picower Institute for Learning and Memory at MIT. Note to listeners: we had a few technical difficulties with the audio quality, so some portions of the interview may be difficult to hear.