Podcasts about health nih

Do the many clinical trials into high-dose vitamin C prove it can actually treat the common cold and cancer, rather than just boost the immune system? Why is there ongoing scepticism? Why are multifactorial chronic diseases so hard to study in clinical trials? What is the right dosage to get the best results from vitamin C?In this episode we have the often misunderstood topic of Vitamin C as an antioxidant to get clear on, particular the high-dose approach and particularly delivered intravenously. Despite a very clear consensus that Vitamin C is a great booster to immune function, research that shows that it helps fight the common cold or flu have been dismissed by doctors and medical researchers; as well as claims that higher doses can increase its efficacy. Other claims that Vitamin C can help fight cardio-vascular disease and even cancer have been with even greater scepticism. So what exactly can vitamin C do to assist our immune function to fight disease, and why is there so much confusion about the answer given the high quantity of clinical trials data?Fortunately today's guest has exactly the right skill set and research knowledge to separate the science from the here-say, medical doctor and orthomolecular medicine researcher, Dr. Richard Z Cheng. Dr. Cheng has a PhD in biochemistry and molecular biology; he's served as a doctor in the US military; he has consulted for the National Cancer Institute, and presented at the National Institute of Health (NIH); he has conducted clinical trials; He is the editor in Chief of the Orthmolecular Medicine New Service; He is also a fellow of the American Academy of Anti- Aging medicine; and has run anti-aging and regenerative medicine clinics in both China and the US for over 20 years.What we discuss:00:00 Intro05:15 Most animals produce Vitamin C in the body, but not primates.06:00 Oxidation & Redox: Giving or receiving an electron.11:00 After reducing oxidation the body recycles it back into vitamin C.14:00 Teamwork: sharing electrons between nutrients and vitamins.18:20 Conventional consensus: good for prevention but not treatment.21:00 Over 80K papers on Vit C on Pub Med!21:30 Linus Pauling Intravenous Vitamin C for cancer and heart disease.27:00 Shortening of common cold and lowering of symptoms - Harri Hemila.29:00 Low dose studies dilute the data on the efficacy of the high dose studies.31:00 Intravenous treatment allows much higher doses safely.33:00 Differences in absorption between IV and oral application.35:20 Pro-oxidant effect only possible at IV high dose.36:30 IV clinical trials.39:20 Cytokine storm cascades in acute respiratory distress.44:00 High Dose IV Vitamin C saved lives in China during Covid 19.50:00 Attacks following Richard's NIH presentation on Vitamin C during covid.57:00 Cardio vascular disease - Vit. C research history.01:01:00 Collagen Synthesis for vascular walls & Vitamin C deficiency.01:07:20 Is the taboo for life style medicine lifting?01:09:30 Issues of gold standard RCT trials not working for multifactorial integrative interventions.01:16:00 Recommendations for preventative use of Vitamin C for listeners. References:E Cameron & Linus Pauling - 'Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer', 1976E.T. Creagan, 'Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer', 1979Harri Hemilä - over 200 meta-analyses and clinical trialsPing Chen et al. 'Pharmacokinetic Evaluation of Intravenous Vitamin C'Richard Z Cheng, ‘Can early and high intravenous dose of vitamin C prevent and treat coronavirus disease 2019 (COVID-19)?'KU Cancer Center researchers announce study of high-dose intravenous vitamin C to treat muscle-invasive bladder cancer, 2024National Cancer Institute overview of IV Vitamin C cancer research.

In this episode of the Heart to Heart Podcast, Dr. Mike Hart sits down with Greg Mushen, a former tech professional turned health advocate, to discuss his incredible journey of transforming his body and lifestyle. Greg shares insights from his background growing up in a medical family and how early exposure to health experiments sparked his long-lasting interest in nutrition and fitness. He details his significant body transformation starting at age 47, the role of tracking macros and engaging in strength training, and the importance of key habits like walking 17,000 steps a day. The conversation also delves into the use of red light therapy, the science behind resistant starches, and maintaining a balanced routine without becoming overly dependent on health gadgets. Greg's shift from a tech-centric life to a health-focused one offers valuable lessons on maintaining physical and mental wellness.   Greg Mushen is a tech veteran turned health optimizer, fitness coach, and writer whose work explores the science of sustainable transformation, metabolic health, and longevity. After a two-decade career in technology, Greg redirected his analytical mindset toward understanding how data-driven habits and consistent routines can radically improve health and well-being. Connect with him on LinkedIn at @GregMushen.   Links: InBody Scale Andrew Huberman, PhD  Jocko Willink  Lane Norton    Show Notes: 00:00 Welcome back to the Hart2Heart podcast with Dr. Mike Hart 01:00 Greg's early interest in health 02:30 The turning point: realizing the need for change 03:30 Greg's transformation and Twitter journey 04:30 Key strategies for transformation 08:00 The importance of walking and daily steps 10:00 Sustaining the transformation: tools and tips 14:23 "At first, tracking my food felt like a second job. But after six weeks, it became automatic—it stopped being effort and started being just who I am." 18:30 Mindset shifts and progress tracking 22:30 The role of LDL in health 27:00 Calories in, calories out debate 30:00 Accurate weight prediction and metabolic studies 31:00 Challenges of calorie tracking and satiation 32:00 Dr. Ted Naman's approach to calorie tracking 33:00 Impact of drinking calories and fiber intake 35:00 Complex carbs and resistant starch 41:00 Benefits of red light therapy 45:30 Nicotine use and addiction 49:00 Tech background and health experimentation 53:30 Future health technologies and personal insights — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

Want to share your feedback? Send us a message!Dr. Shahriar SheikhBahaei, Assistant Professor of Neurobiology and Behavior at Stony Brook University, joins host Sara MacIntyre, M.A., CCC-SLP, to discuss emerging research exploring the cellular and neurobiological mechanisms underlying stuttering. Dr. SheikhBahaei shares his journey from lived experience with stuttering to leading a neuroscience research lab investigating how glial cells, particularly astrocytes, contribute to motor control and speech-related circuits.The conversation delves into several recent studies from his lab that utilize mouse models to uncover how alterations in astrocyte function and iron regulation may relate to the neural pathways involved in stuttering. Dr. SheikhBahaei walks listeners through the background, scientific rationale, and key findings of these studies, highlighting what they reveal about the non-vocal motor aspects of stuttering and how this basic science may inform future directions in understanding and treatment.The episode concludes with reflections on bridging laboratory research with the lived experiences of people who stutter and fostering collaboration among scientists, clinicians, and the stuttering community.Resources discussed:SheikhBahaei, S., et al. (2025). Non-vocal motor deficits in a transgenic mouse model linked to stuttering disorders. bioRxiv. https://www.biorxiv.org/content/10.1101/2025.08.08.669441v2SheikhBahaei, S., et al. (2025). Iron dysregulation in mice engineered with a mutation associated with stuttering. bioRxiv. https://www.biorxiv.org/content/10.1101/2025.07.30.667752v1SheikhBahaei, S., et al. (2024). Scientists, society, and stuttering: A multi-stakeholder approach. International Journal of Clinical Practice. https://onlinelibrary.wiley.com/doi/full/10.1111/ijcp.13678Shahriar SheikhBahaei, Ph.D., is a neuroscientist and faculty member at Stony Brook University. His research focuses on how the brain controls complex motor behaviors such as speech and breathing, particularly focusing on the role of astrocytes in neural circuits. Growing up with stuttering has influenced his lifelong pursuit to understand the neurobiology of speech and communication. He completed his Ph.D. in Neuroscience through a joint program at University College London and the National Institutes of Health (NIH). He later became one of the first Independent Research Scholars at NIH, where he established his own lab. At Stony Brook University, he continues to investigate the cellular and circuit foundations of speech disorders while also mentoring the next generation of scientists and advocating for more inclusive perspectives on communication.

In this episode of the Heart to Heart podcast, Dr. Mike Hart interviews Dr. Corey Peacock, an exercise physiologist and department chair at Nova Southeastern University. Dr. Peacock discusses his diverse background, from establishing the Fight Science Laboratory to working with elite MMA fighters at Kill Cliff Fight Club. The conversation covers advanced training methods, including zone-based cardio, strength and conditioning exercises, and recovery protocols. Listeners gain insights into the importance of athletic balance, the role of power versus strength in MMA, and the efficacy of various recovery tools such as cold plunges, sauna, and red light therapy. Dr. Peacock emphasizes the tailored approach needed for different fighters and the benefits of continually evolving training strategies.   Dr. Corey Peacock is an exercise physiologist, sports scientist, and performance coach who bridges academic research with elite MMA training. He holds a Ph.D. in Exercise Physiology from Kent State University and serves as Department Chair of Health and Human Performance at Nova Southeastern University, where he co-founded the Fight Science Lab. As Director of Athlete Performance for Kill Cliff Fight Club, Dr. Peacock helps world-class fighters optimize strength, endurance, and recovery through science-driven performance methods. Connect with him on Instagram @drcpeacock and LinkedIn. Links: American College of Sports Medicine (ACSM) Kill Cliff Fight Club (formerly Blackzilians and Sanford MMA)  Dr. José Antonio – Co-founder of Fight Science Lab Norwegian 4x4 Interval Method    Show Notes: 00:00 Welcome back to the Hart2Heart podcast with Dr. Mike Hart 00:47 Dr. Corey Peacock's Background 02:52 Cardio Training for MMA Fighters 17:41 Strength and Conditioning Essentials 30:35 Reverse Hypers and Posterior Chain Training 34:17 Balancing Strength and Power in MMA 36:44 Training Insights from Anthony Rumble Johnson 42:42 The Role of HRV in Training Adjustments 47:13 Recovery Tools: Cold Plunges, Sauna, and Red Light Therapy 52:57 Upcoming Events and Contact Information — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

Today on Sauna Talk, we are joined by the dynamic duo of researcher from Emery University, Deanna Kaplan and Roman Palitsky. Deanna Kaplan Deanna Kaplan, PhD is a clinical psychologist with expertise in digital health technologies. She has more than a decade of experience using wearable and smartphone-based technologies to study the dynamics of health processes and clinical change during daily life. Her research is grounded in a whole-person (bio-psycho-social-spiritual) model of health, and much of her work focuses on investigating the dynamics of change of integrative interventions, such as psychedelic-assisted therapies and contemplative practices. Dr. Kaplan is the Director of the Human Experience and Ambulatory Technologies (HEAT) Lab, a multidisciplinary collaboration between the Department of Family and Preventive Medicine and Emory Spiritual Health. More information about the HEAT Lab is here. Dr. Kaplan is the co-creator and Scientific Director of Fabla, an unlicensed Emory-hosted app for multimodal daily diary and ecological momentary assessment (EMA) research. Fabla is an EMA app that can securely collect voice-recorded, video-recorded , and photographic responses from research participants. More information about Fabla is here. Dr. Kaplan holds an adjunct appointment in Emory's Department of Psychology and is appointed faculty for several Emory centers, including the Winship Cancer Institute, Emory Spiritual Health (ESH), the Emory Center for Psychedelics and Spirituality (ECPS), and the Advancement of Diagnostics for a Just Society (ADJUST) Center. She also holds an appointment as an adjunct Assistant Professor at Brown University in affiliation with the Center for Digital Health. Dr. Kaplan received her PhD in Clinical Psychology from the University of Arizona, completed her predoctoral clinical internship at the Alpert Medical School of Brown University, and completed a postdoctoral research fellowship at Brown University, where she received an F32 National Research Service Award (NRSA) from the National Institutes of Health (NIH). Her research is funded by the NIH, the Health Resources Services Administration (HRSA), the Georgia Clinical and Translational Science Alliance, the Tiny Blue Dot Foundation, and the Vail Health Foundation among others. She was named as a 2025 Rising Star by Genomics Press for her work in mental health assessment innovation. Roman Palitsky Roman Palitsky, MDiv, Ph.D. is Director of Research Projects for Emory Spiritual Health and a Research Psychologist for Emory University School of Medicine. His research program investigates the pathways through which culture and health interact by examining the biological, psychological, and social processes that constitute these pathways. His areas of interest include biopsychosocial determinants in cardiovascular health, chronic pain, and grief. In collaboration with Emory Spiritual Health, his research addresses cultural and existential topics in healthcare such as religion, spirituality, and the way people find meaning in suffering, as they relate to health and illness. His work has also focused on the role of religious and existential worldviews in mindfulness-based interventions, as well as implementation and cultural responsiveness of these interventions. Dr. Palitsky's academic training includes a PhD in Clinical Psychology from the University of Arizona with a concentration in Behavioral Medicine/Health Psychology, and a Master of Divinity from Harvard University. He completed clinical internship in the behavioral medicine track at Brown University Warren Alpert Medical School, where he also completed a postdoctoral fellowship. Deanna and Roman were in town attending and speaking at the 2025 SSSR Conference, Society for the Scienific Study of Religion. And as you will hear, we get deep into the spirit of sauna, a spiritual connection we allow ourselves to have, presented to us through the wonderfulness of time on the bench and chilling out in the garden, all misty wet with rain.

In this episode, we explore how mindfulness and yoga can help you decompress stress naturally, both mentally and physically. Modern science continues to confirm what ancient traditions have known for centuries.  That the mind and body are deeply connected, and that mindful presence is one of the antidotes to stress.  Research from institutions like Harvard Medical School and the National Institutes of Health (NIH) shows that mindfulness meditation and yoga lower levels of cortisol---the body's primary stress hormone. They also activate the parasympathetic nervous system, the body's natural “rest and digest” mode, which slows heart rate, improves focus, and promotes emotional regulation. You'll discover simple yet powerful practices that quiet mental distractions, release stored tension, and help you cultivate balance. Learn practical ways to help you navigate life's challenges. Get ready to decompress, improve focus, and feel grounded—whether you're at home, at work, or on the go.

In this solo podcast episode, Dr. Mike Hart delves into the intricacies of insulin resistance, a prevalent yet misunderstood condition. The episode covers the fundamental role of insulin, what happens during insulin resistance, and its linkage to various diseases like diabetes and heart disease. It includes a detailed discussion on how to measure insulin resistance using markers like triglyceride to HDL ratio, fasting insulin, fasting glucose, and hemoglobin A1c. Dr. Hart also explains the significance of advanced glycation end products (AGEs) and how they contribute to aging and diabetes. Practical tips on improving insulin sensitivity through diet, exercise, and supplements such as fiber, mulberry leaf extract, and berberine are provided. Additional considerations for managing blood sugar levels and preventing insulin resistance are also discussed. Links: Fasting Insulin Test: https://medlineplus.gov/lab-tests/insulin-in-blood/ Fructosamine Test: https://medlineplus.gov/lab-tests/insulin-in-blood/ Carnosine: https://examine.com/supplements/carnosine/?show_conditions=true P5P (Pyridoxal-5-Phosphate): https://examine.com/supplements/vitamin-b6/?show_conditions=true Show Notes: 00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 00:56 Understanding Insulin and Insulin Resistance 03:02 Markers and Tests for Insulin Resistance 11:30 Advanced Glycation End Products (AGEs) 14:16 Exercise and Insulin Sensitivity 14:53 "Exercise keeps your body insulin sensitive for up to 48 hours — not just two." 16:21 Nutritional Strategies for Blood Sugar Control 20:59 Supplements and Medications for Blood Sugar Management — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary. Beyond health science, we tackle the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect on social with Dr. Mike Hart: Instagram: https://www.instagram.com/drmikehart/ Twitter: https://twitter.com/drmikehart Facebook: https://www.facebook.com/MikeHartEPS/

Send us a textDr. Fred Grossman, D.O., FAPA is President and Chief Medical Officer of Coya Therapeutics ( https://coyatherapeutics.com/ ), a clinical-stage company focused on developing multi-modality, Regulatory T Cell (Treg) therapies for neurodegenerative diseases. Coya has already developed strong proof of concept data in Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's, and is also active in the autoimmune and metabolic disease domains.Dr. Grossman brings over 20 years of drug development expertise having held senior executive leadership positions in large and small pharmaceutical companies, leading the development and FDA approval of numerous multi-billion dollar blockbuster drugs addressing significant unmet medical needs particularly across CNS disorders. He has close relationships with thought leaders worldwide and has negotiated directly with the FDA and Global Health Authorities for approval of many drugs across therapeutic areas. Dr. Grossman held executive positions at Eli Lilly, Johnson & Johnson, Bristol Myers Squibb, and Sunovion. He served as President and Chief Medical Officer at Glenmark Pharmaceuticals, a $1.5 Billion per annum global pharmaceutical company based in India, overseeing development of an entire pipeline including generics, complex generics including 505(b)(2) candidates, and next-generation biologics (including bi-specific antibodies). Dr. Grossman also previously served as Chief Medical Officer at Mesoblast, Inc., developing allogeneic cellular therapies for inflammatory diseases. Dr. Grossman is Board-Certified in Psychiatry and a Fellow of the American Psychiatric Association and was a Fellow at the National Institutes of Health (NIH). He has held several academic appointments and authored numerous scientific publications.#RegulatoryTCells #Tregs #AutoimmuneDisorders #ShimonSakaguchi #ImmuneSystem #FredGrossman #CoyaTherapeutics #NeurodegenerativeDiseases #AmyotrophicLateralSclerosis #ALS #Alzheimers #CNSDisorders #StanleyAppel #Immunomodulation #ProInflammatoryCytokines #SelfTolerance #Microglia #Macrophages #CTLA4Ig #LowDoseIl2 #FusionProtein #ImmuneCheckpointModulator #FrontotemporalDementia #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

Synopsis: Host Rahul Chaturvedi sits down with Geoffrey Duyk, Chief Executive Officer of Grove Biopharma, for a wide-ranging conversation on navigating today's biotech macro headwinds and building companies that can translate breakthrough science into real patient impact. Dr. Duyk traces his journey from Harvard/Millennium/Exelixis operator to TPG investor and back to company creation, explaining how board dynamics, capital cycles, and policy shifts shape execution. They dig into why this cycle feels uniquely tough—patent cliffs, reimbursement uncertainty, NIH pressures—and who funds innovation in the meantime. Duyk outlines root causes of R&D inefficiency (misaligned capital vs. 20-year timelines, shaky preclinical predictability, costly trials, underused real-world data) and makes the case for rebuilding public trust and STEM education. Then, a deep dive on Grove Biopharma: precision polymer science that creates antibody-like, fully synthetic, cell-permeable protein mimetics to tackle historically “intractable” intracellular protein–protein interactions. Duyk shares design principles, why modular/orthogonal chemistry matters, predictable pharmacology, and lessons from fundraising and board management—plus why he's helping grow a Chicago-centered biotech ecosystem. Biography: Geoffrey M. Duyk, M.D., Ph.D. is the Chief Executive Officer of Grove Biopharma. Dr. Duyk has spent 30 years in the biotechnology industry as an entrepreneur, executive, and investor. Most recently, he was the Managing Partner at Circularis Partners, an investment firm he co-founded, focused on advancing the circular economy and promoting sustainability. Prior to that, Dr. Duyk was Managing Director and Partner at TPG Alternative & Renewable Technologies (ART)/TPG Biotechnology. Before joining TPG, Dr. Duyk served as a board member and President of R&D at Exelixis and was one of the founding scientific staff members at Millennium Pharmaceuticals, where he served as Vice President of Genomics. Earlier in his career, Dr. Duyk was an Assistant Professor in the Department of Genetics at Harvard Medical School (HMS) and an Assistant Investigator at the Howard Hughes Medical Institute (HHMI). While at HMS, he served as a co–principal investigator in the Cooperative Human Linkage Center, which was funded by the National Institutes of Health (NIH). Dr. Duyk is a trustee of Case Western Reserve University, where he serves on the executive committee. He previously served on the Board of Trustees of Wesleyan University and the Board of Directors of the Moffitt Cancer Center. He currently serves on the IR&E (Institutional Research and Evaluation) Committee at Moffitt, a key component of its External Advisory Committee (EAC). He was also a member of the Board of Directors of the American Society of Human Genetics (ASHG), and served as its treasurer. He is a member of the Life Sciences Advisory Board at Innovatus Capital Partners and the Scientific Advisory Board (SAB) for Lawrence Berkeley National Laboratory (DOE). Dr. Duyk previously served on the board of the Jackson Laboratory and on numerous NIH advisory committees. He is currently a Senior Advisor at Qiming Venture Partners (USA) and serves on the boards of Enno DC, Oobli, and Melanyze Dr. Duyk earned both his M.D. and Ph.D. from Case Western Reserve University and completed his medical and fellowship training at the University of California, San Francisco (UCSF). While at UCSF, he was a Lucille P. Markey Fellow and an HHMI postdoctoral fellow. He is a fellow of the American Association for the Advancement of Science.

  In this episode, host Dr. Mike Hart welcomes neuroscientist and author Dr. Ben Rein to discuss his new book, 'Why Brains Need Friends: The Neuroscience of Social Connection.' Dr. Rein shares his journey in neuroscience, his research on autism and MDMA, and his pivot towards science communication. They delve into the devastating effects of loneliness, comparing its impact on mortality to smoking 15 cigarettes a day, and explore why human connections are critical for our brain health. Dr. Rein also discusses the benefits of having pets, the intricate balance of social interactions across a lifespan, the effects of MDMA on feelings of connection, and the role of oxytocin in social bonding. This episode provides a deep dive into the science behind social interactions, offering actionable insights to improve mental health and wellbeing.   Dr. Ben Rein is a neuroscientist, educator, and science communicator whose work explores the biology of human connection, empathy, and social behavior. With a Ph.D. in neuroscience and postdoctoral research at Stanford University, Dr. Rein has studied everything from the neural underpinnings of autism spectrum disorder to how MDMA (ecstasy) enhances empathy in the brain.   Follow his work at mindscience.org or connect with him on Instagram.   Links: Oxytocin (“the love hormone”) Loneliness and mortality studies Stanford University Lion's Mane   Show Notes: 00:00 Welcome back to the Hart2Heart podcast with Dr. Mike Hart 00:30 Dr. Ben Rein's background and new book 02:30 The loneliness epidemic and its effects 04:00 The science behind social interaction 04:15 “ Being isolated is worse for you or as bad for you as smoking 15 cigarettes a day.” 10:30 Extroversion vs. introversion: social needs 24:00 Oxytocin: the love hormone 33:00 Teamwork and social bonds 36:30 The power of tribalism in sports 38:00 Romantic relationships and health 42:00 The impact of loneliness across a lifetime 49:00 Social media and loneliness 01:02:00 The therapeutic potential of MDMA — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

  In this episode of the Heart to Heart podcast, Dr. Mike Hart chats with Dr. Jose Antonio about the evolution and impact of sports nutrition research, particularly focusing on creatine and protein consumption. Dr. Antonio shares his journey from studying muscle physiology to pioneering research in sports nutrition, highlighting the initial skepticism in the scientific community and the eventual acceptance of supplements like creatine. They also delve into the benefits of various supplements for athletic performance, the ongoing debates in the medical field regarding supplementation, and exciting upcoming research on creatine's effects on eye muscle performance in athletes.   Links: University of Central Florida – Dr. Jeff Stout University of Regina – Dr. Darren Candow (Creatine researcher) Protein Intake & High-Protein Diets Caffeine + L-Theanine Combination Show Notes: 00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 00:00 Introduction and guest welcome 01:00 Dr. Jose Antonio's academic journey 01:30 Challenges in sports nutrition research 04:00 Breakthrough in sports supplements 08:00 The evolution of sports nutrition 13:00 High protein diet studies 14:20 “We had people eating 600 to 800 extra calories of pure protein—and nothing happened. No fat gain. That alone blew people's minds.” 17:00 Protein timing and intake 20:30 Impact of hormones on protein absorption 23:00 Testosterone and protein intake 24:00 Peptides and growth hormone 25:00 Protein timing and casein 25:30 Creatine for brain and muscle 42:00 Mitochondrial health and supplements   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

In this episode of Unraveling the Knots, we sit down with researcher-entrepreneur, Asha Kabirou, who beautifully blends science, spirituality, and community building. Asha shares her personal natural hair journey. She explains how simplifying her routine (think gentle care and consistency) helped her embrace her hair's natural beauty and strength.With 6+ years at the National Institutes of Health (NIH), Asha brings some serious science to the conversation. She breaks down the evidence on caffeine and hair growth. Asha also opens up about the importance of community and safe spaces. Tune in for a rich discussion on curls, confidence, community and coffee-preneurship.Send us a textSend your questions about Afro-textured/coily hair to utkinhair@gmail.com.Check out your natural beauty hub, ÈYÍ DÁRA Naturals for natural hair care solutions.Follow us on instagram @utkpodcast

Jon Hartley and Jay Bhattacharya discuss Jay Bhattacharya's vision for the National Institutes of Health (NIH), running the NIH as an innovation accelerator, replication in the sciences, measuring scientist productivity, and the new NIH policy reducing animal testing. Recorded on August 27, 2025. ABOUT THE SERIES Each episode of Capitalism and Freedom in the 21st Century, a video podcast series and the official podcast of the Hoover Economic Policy Working Group, focuses on getting into the weeds of economics, finance, and public policy on important current topics through one-on-one interviews. Host Jon Hartley asks guests about their main ideas and contributions to academic research and policy. The podcast is titled after Milton Friedman‘s famous 1962 bestselling book Capitalism and Freedom, which after 60 years, remains prescient from its focus on various topics which are now at the forefront of economic debates, such as monetary policy and inflation, fiscal policy, occupational licensing, education vouchers, income share agreements, the distribution of income, and negative income taxes, among many other topics. For more information about the podcast, or subscribe for the next episode, click here.

In this episode of the Heart to Heart podcast, Dr. Mike Hart sits down with Dr. Ted Naiman, a family medicine physician from Seattle with a passion for diet and exercise. They discuss the importance of family physicians in healthcare, Dr. Naiman's personal fitness transformation focusing on a high-protein, low-carb diet, and the significance of satiety over counting calories. Dr. Naiman shares his views on effective exercise routines, optimal macronutrient ratios, and the advantages of front-loading protein. They also delve into insulin resistance, the use of fasting triglycerides as a marker, and the potential of GLP-1 medications for weight loss and insulin sensitivity. This comprehensive discussion provides actionable insights into improving metabolic health and body composition. Dr. Ted Naiman is a family physician, author, and leading voice in evidence-based nutrition and metabolic health. With over two decades of experience in primary care, Dr. Naiman has dedicated his career to helping people understand the science of body composition, satiety, and sustainable weight management. Learn more at tednaiman.com  and on LinkedIn.   Links: The P:E Diet — by Dr. Ted Naiman Fairlife Milk (ultra-filtered milk)   Show Notes: 00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 00:30 Dr. Ted Naiman's background 01:30 Transformation journey 02:00 Diet and exercise philosophy 03:00 Calorie counting debate 05:30 Macro ratios and protein focus 09:30 Daily meal timing and strategy 13:27 “Front-load your protein. If you start your day with donuts, you'll eat more all day. If you start with protein, you'll automatically eat less.” 20:30 Sources of protein 25:00 Carbohydrate choices 29:00 Fat sources and supplementation 34:00 Understanding insulin resistance 37:30 Understanding insulin sensitivity and resistance 39:00 Indicators of insulin resistance: triglycerides and HDL 43:30 The role of fasting insulin and glucose 50:30 Training recommendations: cardio vs. weights 52:30 Effective resistance training strategies 59:30 Visceral fat: causes and reduction strategies 01:05:30 The role of GLP-1 in weight management 01:14:30 Conclusion and final thoughts   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

Bob Gatty from Lean To The Left discusses the true consequences of the Donald Trump government shutdown that derails the fight against cancer and Alzheimer's disease. Despite Trump's claims about preventing undocumented immigrants from receiving taxpayer-funded healthcare, federal law already prohibits their eligibility for Medicare, Medicaid, or Affordable Care Act coverage. Gatty reveals the actual human repercussions of the shutdown, including halted Alzheimer's and cancer research funded by the National Institutes of Health (NIH). The shutdown jeopardizes clinical trials, lab funding, and young scientists' careers. Gatty urges viewers to stand against the shutdown and highlights its detrimental effects on essential medical research. For more details, visit his article at LeanToTheLeft.net.CHAPTERS:00:00 Introduction and Trump's Shutdown Claim00:12 The Reality of Immigrant Healthcare00:24 Impact on Alzheimer's and Cancer Research01:10 The Human Cost of the Shutdown01:34 Call to Action and Conclusion

If you started out creating a sexual wellness & intimacy product for men, could you do so for women too? That's the progression of Jeff Abraham, CEO of Promescent and its parent company, Absorption Pharmaceuticals. The company uses science to solve common sexual dysfunction issues with which millions have struggled without an adequate solution - until now. Hear the early challenges in treating premature ejaculation, the discovery of potential treatments for vulvodynia, the gender imbalance in sexual health research & organizations, and how they're addressing unmet needs in women's sexual health. Tune in to this episode to improve sexual wellness & intimacy for both women AND men.   Learn more: Promescent Absorption Pharmaceuticals - Promescent LinkedIn Jeff Abraham   Today's Hot Flash and other stats from: National Institutes of Health (NIH)

In this episode of the Heart to Heart podcast, host Dr.Mike Hart welcomes author Serena Choo, who delves into her journey of writing and overcoming imposter syndrome. They discuss Serena's second book, 'The Monkey and the Way of Zen,' which contains 28 short Zen-inspired stories aimed at providing readers a relaxing and reflective experience. Choo shares insights into the origins of her work, the importance of letting go and subtracting complexities from life, and how personal transformation can be achieved without the burden of constant goal-setting. Additionally, they touch upon topics such as her career transition, the specifics of dealing with imposter syndrome, the concept of emotional intelligence, and the potential benefits of neurolinguistic programming (NLP).   Serena Choo is a transformation coach, author, and thought leader in personal growth and self-discovery. With over two decades of experience spanning corporate finance, executive coaching, and nutritional therapy, Serena has dedicated her career to helping people break free from self-doubt, imposter syndrome, and burnout. She is the author of Letting Go of Imposter Syndrome and The Monkey and the Way of Zen: A Transformation Journey in 28 Short Stories, books that blend practical wisdom with storytelling to inspire reflection, inner peace, and authentic living. Drawing from her background in executive coaching, functional medicine, and NLP, Serena's work emphasizes radical surrender, self-awareness, and creating fulfillment through subtraction rather than constant striving. Learn more about Serena at serenachoo.com Books available on Amazon: Letting Go of Imposter Syndrome and The Monkey and the Way of Zen   Links: Stanford Encyclopedia of Philosophy – Stoicism NLP Association Functional Medicine Coaching Academy Show Notes: 00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 00:30 Discussing Serena's books 02:00 The inspiration behind 'the monkey and the zen' 02:00 Serena's writing journey 04:30 Finding nemo and storytelling 05:30 The essence of zen stories 06:00 Mike's reflection on reading 07:30 Goal setting and personal fulfillment 08:30 Serena's career background 10:00 Transition to coaching 17:00 Imposter syndrome explained 21:30 Techniques to overcome imposter syndrome 27:30 Changing thought patterns 31:30 The role of fortune and stoicism 33:30 Imposter syndrome and self-doubt 34:00 Personal anecdotes and overcoming challenges 38:00 Accepting compliments and authenticity 48:30 Emotional intelligence and reactions 48:50 “To me, emotional intelligence is first about understanding what's going on within yourself — not pushing away the feelings, but being aware of the programs running underneath.” 55:30 Coaching differences between genders 01:00:30 NLP and its benefits   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

In April, Robert F. Kennedy Jr held a press conference about rising diagnoses of autism, and said he would soon be announcing a study to find the responsible agent. Although Kennedy said that environmental factors are the main cause of autism, research has shown that genetics plays a bigger part. Also, the rise in prevalence, many researchers say, is predominantly caused by an increase in diagnoses rather than a true rise in the underlying symptoms and traits.Although the US National Institutes of Health (NIH) announced a US$50 million to fund studies on the causes of autism, many researchers were dismayed that these developments seemed to ignore decades of work on the well-documented rise in diagnoses and on causes of the developmental condition.This is an audio version of our Feature: Autism is on the rise — what's really behind the increase? Hosted on Acast. See acast.com/privacy for more information.

  In this episode of The Heart to Heart podcast, host Dr. Mike Hart interviews Alex Leaf, an independent nutritional researcher renowned for debunking nutritional misinformation on social media. The discussion covers topics such as the benefits of collagen for skin health, the potential advantages of ketogenic diets for athletes, and the truth behind various nutrition myths including the effects of soy on testosterone and semen retention. Alex also shares his insights on intermittent fasting, ideal protein intake, and the debate over seed oils. The conversation concludes with their thoughts on cardiovascular health markers and the relevance of particle size in LDL cholesterol.    Alex Leaf is an independent nutritional researcher, scientific communicator, and educator specializing in human health and performance. With a decade of experience translating complex science into actionable insights, Alex rose to prominence as a researcher and writer at Examine.com before joining Ari Whitten's Energy Blueprint. His work spans peer-reviewed publications—including contributions to the ISSN position stand on ketogenic diets—and teaching in the Master's program in Human Nutrition and Functional Medicine at the University of Western States. Follow him here: Website: alexleaf.com Instagram: @AlexJLeaf   Links: IVF and Abstinence Studies Systematic Review on Ketogenic Diets in Athletes Whey Protein vs. Beef Protein Show Notes: 00:00 – Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 02:30 – Collagen and skin health 08:30 – Ketogenic diets for athletes 14:00 – Protein intake for athletes 18:00 – Intermittent fasting vs caloric restriction 25:00 – Seed oils: myths and facts 30:00 – Semen retention: debunking the myths 35:00 – Soy and hormones 38:30 – Soy consumption and hormonal effects 39:30 – Whey protein: benefits and misconceptions 42:30 – Post-workout nutrition myths 45:00 – Insulin sensitivity and carbohydrate timing 54:00 – Protein intake strategies 57:00 – Calories and diet composition 57:14 – “A calorie is a calorie, but depending on your diet's composition, you'll absorb and utilize very different amounts of calories from food.” 01:01:00 – Debating dietary approaches 01:05:00 – Cardiovascular health markers 01:12:00 – Conclusion and contact information   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

Emotional lability, anxiety, crying jags. Welcome to perimenopause. 70% of women experience depressive symptoms and alterations in mood when estrogen levels plunge or start to fluctuate.  While many factors increase the risk, there is no denying that changes in hormone levels have something to do with anxiety, mood, and depression, even in people who never had issues before perimenopause.     Dr. Pauline Maki is a world-renowned expert in menopause, mood, cognition, and the impact of menopause on the brain. She has authored hundreds of scientific articles and leads a National Institutes of Health (NIH) funded research program on women, cognition, mood, and dementia.  In this episode, we take a deep dive into the science of why women have mood alterations and depression when estrogen levels start to fluctuate.   In this episode:  ·      What it was like to participate in Dr. Jill Biden's  White House Initiative on Women's Health Research ·      The difference between depressive symptoms, mood alteration and depression ·      The risk of recurrence if there is a history of depression during perimenopause ·      The risk of developing depression if there is no history of depression ·      The risk of developing mood alterations if there is no history of depression ·      Windows of vulnerability (pregnancy, post-partum, perimenopause)  ·      What is occurring hormonally in the brain at the level of progesterone and estrogen receptors  ·      The Science Behind Risk Factors for developing depressive symptoms or depression during perimenopause o   Early menopause o   BRCA mutations o   History of major depressive disorder o   Hormone sensitivity in the brain o   Severe menopause symptoms  o   Childhood experiences o   Current life stressors ·      Treatment Options for Perimenopausal Depressive Symptoms o   No treatment- when will it go away? o   Cognitive Behavioral Therapy o   SSRIs o   Hormone Therapy o   NK3 Agonists  o   Progesterone?

In this episode of The Heart to Heart podcast, host Dr. Mike Hart welcomes back Rav, an author and host of the Illusion of Consensus podcast. The conversation delves into Rav's evolving interests, from his initial focus on COVID-19 and myocarditis to his current pursuit of a more holistic and spiritually grounded life. Rav discusses his journey through rigorous psychotherapy, aided by psychedelics, to uncover subconscious patterns and improve his overall well-being. The discussion also touches on the utility of AI tools like ChatGPT as supplementary therapy, the impact of social media on Gen Z's social behaviors, and the rising influence of independent journalism. The episode sheds light on finding balance in a hyper-productive world, integrating different therapeutic pathways, and the significance of peaceful presence in one's life. Rav Arora is an independent journalist, cultural critic, and podcast host exploring the intersections of health, spirituality, and human performance. Rising to prominence through his widely read Substack, The Meta Mystic, and as co-host of The Illusion of Consensus podcast, Rav has become a leading voice challenging mainstream narratives in science, psychology, and culture. Follow him here: Substack: The Meta MysticPodcast: The Illusion of ConsensusTwitter/X: @Ravarora1 Links: Psilocybin & Religious Leaders Study Internal Family Systems (IFS) Pain Reprocessing Therapy (PRT) Show Notes: (00:00)Welcome back to the Hart2Heart Podcast with Dr. Mike Hart (01:00) Shifting gears: From COVID to holistic living (02:30) The role of psychedelics in therapy (04:00) Balancing productivity and relaxation (10:00) ChatGPT as a therapeutic tool (18:30) Exploring psychedelic therapy (28:00) The power of peaceful presence (39:00) Psilocybin study on religious leaders (40:30) Challenges in recruiting for the study (41:00) Gen Z and alcohol consumption (42:30) Impact of social media on social skills (43:00) Dating apps and their consequences (50:48) “Social media has provided this illusion and comfort.” (53:30) Independent journalism's rise (01:00:30) The future of media and podcasting   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

On today’s episode, we interview Dr. Brian Erkkila, the Director of Regulatory Science at Swedish Match North America, a subsidiary of Philip Morris International – makers of ZYN. A former scientist at the Food and Drug Administration’s (FDA) Center for Tobacco Products, Dr. Erkkila offers detailed insights on a new generation of smoke-free products and outlines opportunities for tobacco harm reduction. He also addresses common misconceptions about nicotine and explains how the FDA can do more to arm medical professionals with better advice for their patients who smoke. PMI U.S. recently released a white paper on the topic entitled "Getting Smart on Reduced Harm." Dr. Brian Erkkila is a regulatory scientist with a history of tackling complex regulatory issues, specializing in human health risk assessment, pharmacology, tobacco regulation, database development and science policy. He currently serves as the director of regulatory science at Swedish Match North America, a wholly owned subsidiary of Philip Morris International. Prior to this role, he worked at the Foundation for a Smoke-Free World, the Food and Drug Administration’s (FDA) Center for Tobacco Products, Office of Science, and the National Institutes of Health (NIH). Erkkila holds a BA in Neurobiology from The Johns Hopkins University and earned his PhD in Neurobiology from the University of Alabama at Birmingham. See omnystudio.com/listener for privacy information.

Donna Vogel, MD, PhD, joins us this week to share her journey of recognizing that it was time for retirement and how she optimized her plan using her trademark discipline and scientific vigor to achieve the healthiest possible retirement from a physical, mental, and financial standpoint. This is Dr. Vogel's ninth appearance on the Faculty Factory Podcast, and we are immensely grateful for her selfless and relentless contributions to this community over the years since our 2019 inception. Among her career highlights, she served as Director of the Professional Development Office at Johns Hopkins Medicine and was the Program Director of the Reproductive Medicine grant portfolio at the National Institutes of Health (NIH). She is also a former Jeopardy! champion, having won four consecutive days and reaching the semifinals of the Tournament of Champions. The four pillars of retirement, according to Dr. Vogel, and discussed toward the end of this podcast, are as follows: Financial planning Health and general fitness Things you do for yourself Things you do for others “Above all, keep learning in retirement, as that overlaps with all four pillars and ties them all together. Never stop learning,” Dr. Vogel told us in the closing moments of today's show. Important Resources from Today's Chat Helping Medical Education Faculty Navigate a Post-Academic Landing Pad (Recent Academic Medicine editorial) New York Times article on retirement and mental health referenced by Dr. Vogel The Academy at Johns Hopkins for retired faculty Learning Ally Catch up on Dr. Vogel's Faculty Factory Appearances Networking in a Virtual Environment Applying for Funding, Top Ten Things to Know Be a Memorable Mentor Get That Paper off the Ground How to Turbocharge your Presentation Skills Overcoming Imposter Syndrome Professional Societies, Beyond Getting the Journal Time Management for Faculty Please make sure to listen to today's episode via the podcast player above; and listen to more podcast episodes here.

In this solo podcast episode, Dr Mike Hart provides actionable, evidence-backed strategies to improve overall circadian rhythm and consequently enhance sleep quality. He discusses the importance of a regulated sleep-wake cycle and its impact on hormone release, metabolism, immune function, and general well-being. Various methods to maintain a healthy circadian rhythm are explored, including the benefits of morning sunlight exposure, the role of blue light blocking in the evening, and the timing of meals and exercise. He also touches on the effects of caffeine and alcohol on sleep, the ideal sleep environment, and additional supportive practices like social interaction, light physical activity, and evening routines that promote relaxation.   Links: Dual Orexin Receptor Antagonists (DORAs) Forgiveness & Better Sleep (PubMed) Omega-3 (Fish Oil / EPA)   Show Notes: (0:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart (01:30) Natural sleep improvement tips (02:33)  "Cortisol isn't bad—it's about timing. You want it high in the morning and low at night for better sleep." (04:30) Behavioral modifications and supplements (08:30) Introduction to prescription sleep medications (10:00) Dual orexin receptor antagonists (DORAs) (14:30) Z-Drugs: Benefits and risks (18:00) Benzodiazepines: Usage and caution (20:30) Doxepin and H1 inverse agonists (22:30) Gabapentinoids for sleep and pain (26:30) Alpha adrenergic agents (31:30) Sedating antidepressants (37:30) Sodium oxybate for narcolepsy — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

His name is Dr. Elias Zerhouni, former director of the National Institutes of Health (NIH) under President George W. Bush, presidential envoy under President Barack Obama and treating physician for President Ronald Reagan. He is the author of "Disease Knows No Politics," an inspirational medical and political memoir that champions the work of the NIH, and he is our guest on the next Another View on Health. Dr. Zerhouni will share why, despite deep cuts in funding by the Trump administration, he believes the NIH needs to be at the service of all Americans, regardless of their political preferences, race, gender, sexual orientation or religion.

In this episode of the Heart to Heart podcast, Dr. Mike Hart hosts Dr. Chester Sokolowski, a peptide expert and the founder of Thrive Telehealth Clinic, which specializes in hormone replacement therapy (HRT) and peptide treatments for both men and women. Dr. Sokolowski discusses his background, career, and various business ventures focused on human performance and optimization. The conversation delves deep into the benefits and applications of testosterone replacement therapy (TRT), peptides, and other health-related topics. Key points include the implications of TRT, managing estrogen levels, the benefits of combining peptides for muscle growth and recovery, and the groundbreaking potential of GLP-1 agonists like Ozempic and Retatrutide for weight loss and metabolic health. Dr. Sokolowski also touches on the benefits of glutathione, the latest research on peptides such as BPC-157 and TB-500, and the ethical considerations of using these therapies in professional sports. Dr. Chester Sokolowski is a performance optimization expert, telehealth clinician, and leading voice in hormone and peptide therapy. He earned his doctoral training at Florida State University and has dedicated his career to human performance, healthspan, and longevity. Known online as “Dr. Soko”, he shares cutting-edge insights on testosterone therapy, peptides, recovery, and performance through social media and educational content. His work empowers people to look, feel, and perform at their absolute best. Follow him on Instagram: @dr.soko, LinkedIn: Dr. Chester Sokolowski and YouTube: Dr. Soko Links: TRT (Testosterone Replacement Therapy) Ozempic (Semaglutide) DIM (Diindolylmethane) Oxidative stress & disease   Show Notes: (00:00) Introduction to the Heart to Heart Podcast (02:30) Dr. soko's dissertation on binge drinking and muscle growth (06:00) Cold therapy and hypertrophy (08:00) TRT and arimidex discussion (13:35) “Estrogen is not the enemy; it's actually protective for your heart, your brain, your joints.” (14:30) HCG and fertility (20:00) Peptides and GLP-1 drugs (34:30) Minimizing side effects and dosage strategies (35:30) Understanding GLP-1 mechanisms (36:00) Red aide: the unique GLP-1 (39:00) Visceral fat and GLP-1 effectiveness (41:00) GLP-1s and impulse control (46:30) Glutathione: the ultimate antioxidant (50:30) Peptides for skin and hair health (51:00) Growth hormone peptides: which is best? (55:00) BPC-157 and tb-500: healing peptides (01:00:30) TRT, peptides, and sports (01:03:00) Conclusion and contact information   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

In this solo podcast episode, Dr Mike Hart provides actionable, evidence-backed strategies to improve overall circadian rhythm and consequently enhance sleep quality. He discusses the importance of a regulated sleep-wake cycle and its impact on hormone release, metabolism, immune function, and general well-being. Various methods to maintain a healthy circadian rhythm are explored, including the benefits of morning sunlight exposure, the role of blue light blocking in the evening, and the timing of meals and exercise. He also touches on the effects of caffeine and alcohol on sleep, the ideal sleep environment, and additional supportive practices like social interaction, light physical activity, and evening routines that promote relaxation.   Links: Luminette 3 Glasses Light Therapy Box (10,000 lux standard) The Paleo Solution (Book)   Show Notes: (0:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart (02:00) Morning sunlight: The key to a healthy circadian rhythm (07:00) Evening strategies for better sleep (09:00) Exercise and movement: Timing and types (14:30) Meal timing and its impact on sleep (19:00) The role of melatonin and caffeine (20:41) “Caffeine within six hours of bed can cost you a full hour of sleep.” (25:00) Alcohol and other sleep disruptors (30:00) Optimizing your sleep environment (33:00) Pre-sleep relaxation techniques — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

In this edition of the Heart to Heart podcast, Dr. Mike Hart sits down with Todd Shapiro, CEO of Red Light Holland, a prominent figure in the psychedelic space. They discuss various aspects of psychedelic therapy, particularly focusing on psilocybin and its potential benefits for mental health, anxiety, and personal well-being. Todd shares his personal journey from working various jobs to becoming a key player in the psychedelic industry. They delve into recent developments in psychedelic research, the challenges of legalization, and the importance of proper protocols and responsible use. The conversation also highlights the role of microdosing and macro dosing, the differences between medicinal mushrooms and other psychedelics like MDMA and ayahuasca, and the future of psychedelic therapy.  Guest Bio and Links Todd Shapiro is the CEO of Red Light Holland, a publicly traded leader in legal psilocybin truffles and psychedelic research. A former top Canadian radio host turned mental health advocate, Todd champions safe, science-backed access to psychedelics, working with world-class researchers to advance policy reform and personal sovereignty. Follow him on X (Twitter) @ToddMShapiro Red Light Holland: http://redlight.co Third Wave: https://thethirdwave.co/microdosing-psilocybin-mushrooms-stamets-stack/?utm_source=chatgpt.com schedule35.co: https://schedule35.co/blog/paul-stamets-microdosing-protocol/?utm_source=chatgpt.com Show Notes: (00:00) Introduction to the Heart to Heart Podcast (01:30) Todd Shapiro's journey into psychedelics (03:30) Microdosing and its impact (13:30) Challenges and legalities of psychedelics (19:30) Advocacy and future of psychedelics (32:00) Concerns about unregulated psilocybin use (34:00) Regulated psilocybin sales in the Netherlands (37:00) Psilocybin administration methods (46:36) “The most clear anecdotal model of consistency… has got to be psilocybin. “ (49:30) Corporate influence on psychedelics (57:30) Global leadership in psychedelic research (59:30) Closing remarks and future prospects   --- The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart:   Instagram: https://www.instagram.com/drmikehart/  Twitter: https://twitter.com/drmikehart   Facebook: https://www.facebook.com/MikeHartEPS/   

The mechanisms behind Alzheimer's disease have eluded scientists for decades. But a new breakthrough points to lithium as a possible explanation—not only does it occur naturally in the brain, but a deficiency causes dementia in mice. This research is one of thousands of projects that have lost funding due to President Trump's cuts to the National Institutes of Health (NIH). Host Ira Flatow speaks with Alzheimer's researcher Bruce Yankner about this new finding, and then to epidemiologist Katelyn Jetelina and immunologist Elisabeth Marnik about the country's “quiet engine of science,” the NIH.Guests: Dr. Bruce Yankner is professor of genetics and neurology at Harvard Medical School in Boston, Massachusetts.Dr. Katelyn Jetelina, epidemiologist and author of the Your Local Epidemiologist newsletter. She's based in San Diego.Dr. Elisabeth Marnik is an immunologist and Director of Science Education & Outreach at the MDI Biological Laboratory in Bar Harbor, Maine.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

In today's episode, we're diving deep into the intricate world of federal procurement, uncovering vital insights that could reshape your business strategy. Our guest, a seasoned entrepreneur, takes us on a journey through the maze of federal acquisition regulations and the diverse landscape of small business opportunities. Our discussion revolves around the power play between GSA (General Services Administration) schedules, Best in Class contracts, and small business set-asides. Our guest dissects the nuances of FAR (Federal Acquisition Regulation) Part 8, Part 16.5, and Part 19, shedding light on the discretionary nature of small business set-asides. We explore the dynamics within various government agencies, particularly spotlighting the labyrinthine structure of the National Institutes of Health (NIH) and Health and Human Services (HHS). This episode is a goldmine for entrepreneurs aiming to crack the federal procurement code, as we unravel the complexities, share practical strategies, and empower you to make informed decisions. Catch you next time on The Daily Windup for more entrepreneurial insights!

In this episode, we sit down with Mr. Wayne Berry, a Senior Procurement Analyst and Small Business Specialist at the National Institutes of Health (NIH), part of the Department of Health and Human Services. With over 15 years of experience in federal contracting, Wayne provides valuable insights into how small businesses can navigate the complex landscape of government procurement. He breaks down the differences between agencies, highlighting the contrast between Veteran Affairs and HHS, shedding light on how each agency's unique mission shapes their purchasing strategies. Wayne emphasizes that understanding not just what an agency buys, but how they buy it, is crucial for success. From GSA schedules to the nuances of the small business program, Wayne's expertise shines through as he simplifies intricate concepts for newcomers to the world of federal contracting. Join us as Wayne Berry guides us through the intricate world of government contracts, offering practical advice for small businesses seeking to make their mark. Remember, government contracts might seem like one big entity, but it's a landscape made up of diverse agencies with distinct approaches to procurement. Tune in to this episode to learn how to navigate the system and position your small business for success!

This Day in Legal History: National Security Act of 1947On this day in legal history, July 25, 1947, Congress passed the National Security Act of 1947, fundamentally reshaping the American national security infrastructure in the wake of World War II. The legislation created a unified framework to coordinate defense and intelligence operations, aiming to prevent the bureaucratic fragmentation that had plagued wartime decision-making. One of its central provisions was the formation of the National Security Council (NSC), designed to advise the president on domestic, foreign, and military policies related to national security.The Act also established the Central Intelligence Agency (CIA), which replaced the wartime Office of Strategic Services (OSS) and became the first peacetime intelligence agency tasked with gathering, analyzing, and coordinating intelligence. Additionally, it created the National Military Establishment (later renamed the Department of Defense in 1949), which consolidated the War Department and the Navy Department under a single executive authority.Within the National Military Establishment, the Act preserved the autonomy of the Army and Navy while officially creating a separate branch: the United States Air Force. It also formalized the Joint Chiefs of Staff to provide coordinated military advice to civilian leadership. These structural reforms sought to ensure more cohesive planning and execution of U.S. defense policy during a time of growing Cold War tensions.The legislation marked a profound shift in how the federal government approached global strategy, institutionalizing the military-intelligence bureaucracy that would define American power projection for decades. It also laid the legal groundwork for the modern national security state, with broad implications for executive authority, covert operations, and civil-military relations. As Cold War dynamics evolved, the institutions born from this Act became central to both overt diplomacy and covert action around the world.Ghislaine Maxwell, currently serving a 20-year sentence for aiding Jeffrey Epstein's abuse of minors, is petitioning the U.S. Supreme Court to overturn her conviction. Her legal team argues that a 2007 non-prosecution agreement made with Epstein in Florida should have shielded her and other associates from future federal prosecution. The case raises a significant legal issue: whether plea deals made by one U.S. Attorney's Office bind other federal jurisdictions. This question has divided circuit courts, increasing the chances the Supreme Court might take up the case when justices return from summer recess in late September.The Justice Department under Trump acknowledged the legal split but urged the Court to deny Maxwell's appeal, arguing that plea agreements are binding only between the negotiating parties. Maxwell's defense contends the 2007 deal's broad language promised immunity for co-conspirators nationwide, and that allowing prosecutors to renege undermines trust in the justice system. The National Association of Criminal Defense Lawyers supports her petition, citing the widespread use of plea agreements in American jurisprudence.The case unfolds amid renewed political pressure over Epstein-related disclosures, with Trump's administration walking back earlier commitments to release more records. The political sensitivity may affect the Supreme Court's willingness to get involved, especially given the presence of three Trump-appointed justices. Columbia Law professor Daniel Richman noted the unusual breadth of Epstein's original deal might make this a poor case for setting a national precedent, despite its legal significance.Amid Epstein furor, Ghislaine Maxwell seeks relief from US Supreme Court | ReutersThe Trump administration has asked the U.S. Supreme Court to allow it to implement major funding cuts to National Institutes of Health (NIH) grants, arguing the cuts align with its broader effort to dismantle federal diversity, equity, and inclusion (DEI) programs. A lower court had blocked the move in June, with U.S. District Judge William Young ruling that the cuts were unlawfully arbitrary and lacked clear justification, violating administrative law. The decision came after lawsuits from a coalition of researchers, public health groups, and 16 states led by Democratic administrations, who argued the grant cancellations were politically motivated and targeted research associated with DEI or gender identity.The administration contends that continuing to pay the $783 million in grants contradicts its policy goals. The Justice Department is also challenging the venue of the lawsuits, arguing they should have been brought in the Court of Federal Claims, which specializes in monetary claims against the federal government. The 1st U.S. Circuit Court of Appeals recently rejected that argument, refusing to pause Judge Young's ruling.Judge Young, despite being a Reagan appointee, sharply criticized the administration's actions as lacking any rational explanation and as ideologically driven. He noted that officials failed to define DEI while broadly discrediting grant-supported research without evidence. Critics, including NIH employees and scientists, have warned that the cuts undermine scientific integrity and public health.The Supreme Court, now with a 6-3 conservative majority, has been receptive to Trump administration appeals in similar cases. In April, it allowed comparable cuts to teacher training grants to proceed. The administration hopes for a similar result in this case.Trump administration asks US Supreme Court to allow NIH diversity-related cuts | ReutersGlass Lewis and Institutional Shareholder Services (ISS), two leading proxy advisory firms, have filed lawsuits against Texas over a new state law restricting their ability to advise shareholders on environmental, social, governance (ESG), and diversity, equity, and inclusion (DEI) matters. Proxy advisors provide independent recommendations to institutional investors—such as pension funds and asset managers—on how to vote on issues at shareholder meetings, including board elections, executive compensation, and corporate policies. This means their influence is significant in shaping corporate governance across markets.The new Texas law, signed by Governor Greg Abbott, requires these advisors to include disclaimers stating their recommendations may not be in the financial interest of shareholders and to back up ESG or DEI-related advice with financial analysis. Glass Lewis and ISS argue the law violates their First Amendment rights by forcing them to include government-mandated speech that contradicts their independent analysis and perspectives.Filed in federal court in Austin, the lawsuits name Attorney General Ken Paxton as the sole defendant. Both firms contend the law is politically motivated and will damage their reputations, cost them clients, and undermine shareholder oversight of corporate boards. ISS also criticized the law as serving to protect corporate executives from accountability, labeling it "anti-capitalist" and counter to shareholder interests.The legal challenge comes amid a broader rollback of corporate DEI programs nationwide and is part of a trend in Republican-led states to push back against what they see as left-leaning influence in financial decision-making. The law is scheduled to take effect on September 1, unless blocked by the court.Glass Lewis, ISS sue Texas over law limiting DEI, ESG proxy advice | ReutersThis week's closing theme is by Enrique Granados.This week's closing theme is Granados' masterwork Goyescas, Op. 11, a piano suite composed in 1911 and widely regarded as the Spanish composer's magnum opus. Subtitled Los majos enamorados (The Gallants in Love), the suite captures the spirit and elegance of 18th-century Madrid, evoking a romanticized world of passionate young lovers, elaborate dress, and melancholic reverie. Granados drew inspiration from the art of Francisco Goya, though the individual pieces are not linked directly to specific paintings. Instead, they are tonal impressions—musical vignettes steeped in the colors and textures of Goya's Spain.Goyescas is divided into two books. Granados premiered Book I on March 11, 1911, at the Palau de la Música Catalana in Barcelona, showcasing his own virtuosic pianism. Book II followed in December of that year and was first performed in Paris at the Salle Pleyel on April 2, 1914. Each movement in the suite is rich with rhythmic flair, lyrical warmth, and emotional depth, capturing the elegance of Spanish courtship rituals and the melancholy undercurrents of unfulfilled longing.The suite's most famous piece, Quejas, o La Maja y el Ruiseñor (Lament, or The Maiden and the Nightingale), would later be famously echoed in the song “Bésame Mucho.” Granados' idiomatic use of ornamentation, rubato, and folkloric rhythms set a high watermark for Spanish piano music and influenced later composers such as Albéniz and Falla. Through Goyescas, Granados created a work that is both a tribute to Goya's vision and a deeply personal expression of turn-of-the-century Spanish romanticism.Without further ado, Enrique Granados' The Gallants in Love, the third movement, El Fandango del Candil. Enjoy! This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.minimumcomp.com/subscribe

In this episode, Dr Tsen Vei Lim talks to: Dr Marilyn Piccirillo from the Department of Psychiatry at Rutgers University-New Brunswick and Drs Katherine Walukevich-Dienst and Elizabeth Lehinger from the Department of Psychiatry and Behavioral Sciences at the University of Washington School of Medicine. The interview covers their research report on the longer-term efficacy of brief, alcohol-focused personalised feedback interventions among young adults in two universities on the West coast of the US. Note for listeners: The acronym PFI is used throughout this episode, which stands for ‘personalised feedback intervention'.· What is an alcohol-focused personalised feedback intervention? [01:48]· An example of how one of these interventions would work in practice [03:03]· The importance of considering distress [03:46]· The key findings of the study [07:24]· Why ‘less is more' when it comes to alcohol interventions [12:19]· How the findings contribute to policy or practice [14:46]· The pioneers of personalised feedback interventions [17:41]About Marilyn Piccirillo: Dr Piccirillo is a licensed psychologist and an Assistant Professor in the Department of Psychiatry at Rutgers University-New Brunswick. She is also a Core Faculty member of the Rutgers Brain Health Institute and a member of the Rutgers Addiction Research Center. Dr Piccirillo uses person-centered frameworks to study motivating and maintenance factors for substance use problems, particularly for those experiencing co-occurring anxiety, trauma, and stress. She also examines how digital tools can be used to support treatment and recovery and optimise the design and delivery of treatments for substance use problems and addiction. About Katherine Walukevich-Dienst: Dr Walukevich-Dienst is a clinical psychologist and Assistant Professor in the Department of Psychiatry and Behavioral Sciences at the University of Washington. Her research focuses on developing and testing digital interventions to reduce substance use and improve mental health among young adults. She uses methods such as ecological momentary assessment to examine real-time behavior and intervention engagement. Dr Walukevich-Dienst has authored over 50 peer-reviewed publications and leads National Institutes of Health (NIH)-funded projects aimed at improving outcomes for cannabis and alcohol use through scalable, evidence-based approaches. About Elizabeth Lehinger: Dr Lehinger is an Acting Assistant Professor in the Department of Psychiatry and Behavioral Sciences at the University of Washington School of Medicine. She has two primary areas of research: 1) college student alcohol prevention, and 2) trauma recovery for individuals with co-occurring substance use disorders. Her research focuses on reward processes underlying these research areas. The authors have no conflicts of interest to disclose. Original article: Examining the longer-term efficacy of brief, alcohol-focused personalized feedback interventions for individuals with internalizing distress: Secondary analysis of a randomized controlled trial. https://doi.org/10.1111/add.70044 The opinions expressed in this podcast reflect the views of the host and interviewees and do not necessarily represent the opinions or official positions of the SSA or Addiction journal. The SSA does not endorse or guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information. Hosted on Acast. See acast.com/privacy for more information.

Research funded by the federal government has been crucial in many of the defining technologies of our time: the internet, A.I., crispr, Ozempic, and the mRNA vaccines first used widely in the COVID pandemic. Between 2010 and 2019, more than 350 drugs were approved in the United States, and virtually all of them could trace their roots to the National Institutes of Health (NIH). Now this administration is endangering our health by cutting funds to academic medical centers. Moreover, there are threats to Medicaid, as well as ongoing cuts to the Centers for Disease Control (CDC). Many universities have paused hiring due to the uncertainty at the NIH and are curtailing graduate programs. Biotech investors are warning of a contraction in medical innovation. NIH grants have been terminated on ideological grounds, which have resulted in clinical trials shutting down. Global health programs worldwide have been cut. A discussion on these destructive policies on medicine in our country is needed. About the Speaker Monica Gandhi M.D., M.P.H., is a professor of medicine and associate chief in the Division of HIV, Infectious Diseases, and Global Medicine at the University of California, San Francisco (UCSF). She is also the director of the UCSF Center for AIDS Research (CFAR) and the medical director of the HIV Clinic ("Ward 86") at San Francisco General Hospital. She serves as the associate program director of the ID fellowship at UCSF. Her research focuses on HIV treatment and prevention optimization, HIV and women, adherence measurement in HIV and TB, adherence interventions, and on optimizing the use of long-acting antiretroviral therapy (ART). She is a long-standing NIH-funded researcher. Commonwealth Club World Affairs of California is a nonprofit public forum; we welcome donations made during registration to support the production of our programming. A Health & Medicine Member-led Forum program. Forums and Chapters at the Club are organized and run by volunteer programmers who are members of The Commonwealth Club, and they cover a diverse range of topics. Learn more about our Forums. Commonwealth Club World Affairs is a public forum. Any views expressed in our programs are those of the speakers and not of Commonwealth Club World Affairs. OrganizerMichael Baker  Learn more about your ad choices. Visit megaphone.fm/adchoices

Your mindset is a set of beliefs that shape how you makesense of the world and yourself. It influences how you think, feel, and behavein any given situation. It means that what you believe about yourself impactsyour success or failure. Research suggests a significant and growing number ofathletes utilize these techniques for performance enhancement and mentalwell-being. A study cited by the National Institutes of Health (NIH) found that96% of athletes surveyed reported knowledge of at least one mental technique,and a significant portion used them before competitions or for regenerationafter injuries. Furthermore, a New York Times article highlights the growingrecognition of deep breathing as a valuable tool for athletes, suggesting itsuse is not niche but rather becoming more mainstream.Jure Koscak was a professional table tennis player for 15years. During his career, he did a lot of research on sports psychology, and inthe last 15 years, after earning a Ph.D. in physical education, he hasspecialized as a mental coach for high performance. He has been working withmore than 50 professional athletes from different sports and more than 1000private clients. He is fluent in Slovenian, English, Spanish, German,Serbo-Croatian, and French. Jure is always inquiring about life and how tocontribute as much as possible so that athletes and others can strive andthrive in their arenas of life and sports. Lately, he has been using the AEQmethod to relax chronic pain and increase emotional maturity.For more information: https://www.thegenuineathlete.com/Follow: @genuine_athlete.jk

During this episode of Soundbites of the Annual Meeting, we spoke with P.J. Brooks, PhD, who is Deputy Director of the Division of Rare Diseases Research Innovation, part of the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH). In his conversation with ASGCT's Communications Committee Chair, Lynnea Olivarez, Dr. Brooks talked about: The impact of developing cell and gene therapies as platforms to treat more than one disease Projects he's involved in that are working towards the platform approach What's giving him hope right now about the future of the field Listen and subscribe to the ASGCT Podcast Network so you don't miss any episodes! Did you attend the 28th Annual Meeting? Watch all sessions on demand on the virtual meeting platform through July 18! Show your support for ASGCT!: https://asgct.org/membership/donateSee omnystudio.com/listener for privacy information.

In this episode of "Ask the Expert," Dr. Matthew Bellman joined Dr. GG deFiebre of SRNA to explain the basics of functional electrical stimulation (FES) and its applications. Dr. Bellman outlined how FES differs from other electrical stimulation techniques and its role in improving mobility for those with neuroimmune disorders [00:03:35]. He discussed the specific benefits of FES, including muscle strengthening and managing spasticity, and shared success stories demonstrating its impact [00:09:53]. Dr. Bellman also highlighted new developments in FES technology, particularly the integration of AI [00:33:28].Matthew Bellman, PhD is a Founder and the Chief Technology Officer for MYOLYN, Inc. Dr. Bellman is a Triple-Gator with bachelor's, master's, and doctorate degrees in mechanical engineering from the University of Florida (UF). In 2013, Dr. Bellman co-founded MYOLYN to commercialize his doctoral research on mobility assistance for people with paralysis and muscle weakness using functional electrical stimulation (FES) and robotics. In his time at MYOLYN, Dr. Bellman has been responsible for building a certified medical device quality management system, managing a team of engineers in the design and development of two Class II medical devices, obtaining grant funding from the National Institutes of Health (NIH), and growing a small business. Dr. Bellman has been awarded the Entrepreneurial Spirit Award by UF's Center for Entrepreneurship and Innovation, the O. Hugo Schuck Best Paper Award by the American Automation Control Council, and the Outstanding Young Alumnus Award by the UF Department of Mechanical and Aerospace Engineering. In 2019, Dr. Bellman secured MYOLYN's place as a finalist in the Toyota Mobility Unlimited Challenge. In addition to his role at MYOLYN, Dr. Bellman has also served as a member of the Board of Directors for NextStep Orlando's Paralysis Recovery Center and as a member of the Advisory Council for the American Bionics Project. Dr. Bellman's work has been published in high-impact scientific journals including Muscle & Nerve, IEEE Transactions on Control Systems Technology, and The Journal of NeuroEngineering and Rehabilitation, and he has been an invited guest speaker at universities around the world including UF, École Normale Supérieure (ENS) de Lyon, and the Tokyo Institute of Technology. When not at work, Dr. Bellman can be found trail running or relaxing at home with his wife and family.00:00 Introduction00:31 Meet Dr. Matthew Bellman00:52 Understanding Functional Electrical Stimulation (FES)01:30 Historical Context and Early Applications of FES03:35 How FES Works in the Body07:05 FES for Spinal Cord Damage and Neuromuscular Disorders09:53 Benefits of FES for Various Symptoms13:44 Evidence and Secondary Benefits of FES17:47 Typical FES Session and Accessibility24:06 Success Stories and Patient Feedback29:25 Barriers to FES Adoption33:28 Future Developments in FES Technology36:46 Final Thoughts and Encouragement

Substack is where I discovered Dr. MeiLan Han! I was browsing through and was pleasantly surprised to read an article, and learn that she wrote a book called, Breathing Lessons. And to top it off, she's from my home state of Michigan. I also learned the Dr. Han's book was “a passion project during the pandemic.”I'm delighted to share a conversation with Dr. MeiLan Han, one of the country's most respected voices in lung health and a tireless advocate for people living with chronic respiratory conditions.Dr. Han is a Professor of Medicine and Chief of Pulmonary and Critical Care at University of Michigan Health. She's not only cared for patients at the bedside but has devoted her career to understanding lung disease at its roots, with a special focus on chronic obstructive pulmonary disease (COPD), a condition that remains widely under-recognized and underfunded. Through her research, Dr. Han is helping to uncover how diseases like COPD affect the lungs in different ways, with the goal of making treatment more precise, more effective, and more personalized.Her journey began at the University of Washington and continued through specialized training at the University of Michigan, where she also earned a Master's degree in Biostatistics and Clinical Study Design. Today, she leads research funded by the National Institutes of Health (NIH), serves on national advisory boards for the COPD Foundation and the American Lung Association, and contributes to global guidelines that shape how lung disease is diagnosed and treated.Dr. Han also serves as Deputy Editor of the American Journal of Respiratory and Critical Care Medicine, helping to guide the direction of clinical practice and research in pulmonary medicine.If you or someone you love is living with a chronic lung condition, Dr. Han's insight is not only encouraging, it's essential. I'm so grateful to bring her voice to this platform. How many breathes do we take in a lifetime? It's fascinating to discuss and you'll hear the answer in our podcast.Lung health, do you think about it?To get her book: https://www.amazon.com/Breathing-Lessons-Doctors-Guide-Health-ebook/dp/B08X2ZFGNZ/ref=tmm_kin_swatch_0 Please like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredThanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/en

Since January, the National Institutes of Health (NIH) has made sweeping cuts to science. It's hard to keep track of how many research grants were canceled, but they add up to hundreds of millions—possibly billions—of dollars of research funding lost. Some scientists, like Dr. Katie Edwards, are taking the fight to the courts. Edwards studies interpersonal violence at the University of Michigan, and she speaks with Host Flora Lichtman about why she's suing the NIH.Guest: Dr. Katie Edwards is the director of the Interpersonal Violence Research Laboratory and a professor of social work at the University of Michigan. She studies violence against marginalized communities.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

FedEx's board of directors elected R. Brad Martin as chairman following the passing of founder Fred Smith, and a decision to reduce the board's size to 12 members. The company expressed profound gratitude for Smith's vision and contributions, as Martin, previously vice chairman, now leads the audit and finance committees. Maersk has suspended services to Israel's busiest port, Haifa, and halted cargo acceptance due to ongoing conflict and safety risks from missile attacks. This decision was made prior to new missile attacks, which occurred despite reports of a potential ceasefire. The National Institutes of Health (NIH) has announced a five-year, $10 million research initiative to study the long-term health effects of the 2023 railroad derailment in East Palestine, Ohio. This marks the first large-scale coordinated federal program to address community health concerns, focusing on public health tracking, chemical exposure impacts, and multi-disciplinary communication. Also, tune into FreightWaves TV for programs like Check Call and Loaded and Rolling, and mark your calendars for upcoming events like the Enterprise Fleet Summit on July 23rd. Don't miss the Supply Chain AI Symposium on July 30th in Washington D.C., where a special ticket offer allows combining it with your F3 ticket for a reduced price. Learn more about your ad choices. Visit megaphone.fm/adchoices

Tuesday, June 10th, 2025Today, Pete Hegseth has mobilized the United States Marines against American citizens in Los Angeles County; Attorney General Bonta is suing the Trump administration seeking an injunction of National Guard deployment; ABC suspends Terry Moran for a tweet calling Stephen Miller a world class hater; a former Afghan soldier was arrested by ICE in Houston and stripped of his asylum protections; Pam Bondi's brother gets TROUNCED in the DC Bar Association election; Israeli forces detain Greta Thunberg after halting the Freedom Flotilla boat carrying aid and supplies; NIH employees publish the Bethesda declaration in dissent of Trump's cuts; RFK Jr ousts the entire CDC vaccination advisory committee; and Allison and Dana deliver your Good News.Thank You, CBDistilleryUse promo code DAILYBEANS at CBDistillery.com for 25% off your purchase.  Specific product availability depends on individual state regulations.Thank You, PacagenFor an extra 25% off your order and a special gift, head to Pacagen.com/DAILYBEANS.MSW Media, Blue Wave California Victory Fund | ActBlueMarines Unleashed In LA! Trump's Authoritarian Crackdown Intensifies with Allison GillCheck out Dana's social media campaign highlighting LGBTQ+ heroes every day during Pride Month -  Dana Goldberg (@dgcomedy.bsky.social) StoriesTrump administration activates 700 Marines in Los Angeles area amid ICE protests |CBS NewsFormer Afghan soldier arrested at Houston-area home by ICE, stripped of asylum protections, attorney says | Houston Public MediaGaza-bound aid boat with Greta Thunberg on board arrives in Israel after its seizure | AP NewsRFK Jr. ousts entire CDC vaccine advisory committee | AP NewsABC Suspends Terry Moran for Calling Stephen Miller a ‘World-Class Hater' | The New York TimesPam Bondi's brother overwhelmingly defeated in heated race to lead the D.C. Bar | NPR Good Trouble: - STAND UP FOR SCIENCE - On June 9th, 2025, federal employees at the National Institutes of Health (NIH) bravely stood up for the health and safety of the American people and faithful stewardship of public resources by authoring and signing the Bethesda Declaration. Sign the Open Letter in Support of NIH Public Servants - Action NetworkProton Mail: free email account with privacy and encryptionFind Upcoming Demonstrations And ActionsSat June 14 10am – 12pm PDT AG is hosting NO KINGS Waterfront Park, San DiegoDonation link - secure.actblue.com/donate/fuelthemovement250th Anniversary of the U.S. Army Grand Military Parade and Celebration50501 MovementJune 14th Nationwide Demonstrations - NoKings.orgIndivisible.orgFederal workers - feel free to email me at fedoath@pm.me and let me know what you're going to do, or just vent. I'm always here to listen. Check out other MSW Media podcastsShows - MSW Media, Cleanup On Aisle 45 podSubscribe for free to MuellerSheWrote on SubstackThe BreakdownFrom The Good NewsNational Portrait GalleryNobody Listens to Paula PoundstoneProtesters' Rights | American Civil Liberties UnionTAKE THE PLEDGE: Don't Rank Eric or Andrew for Mayor - Action Network Reminder - you can see the pod pics if you become a Patron. The good news pics are at the bottom of the show notes of each Patreon episode! That's just one of the perks of subscribing! patreon.com/muellershewrote Federal workers - feel free to email me at fedoath@pm.me and let me know what you're going to do, or just vent. I'm always here to listen.Share your Good News or Good TroubleMSW Good News and Good Trouble Check out other MSW Media podcastshttps://mswmedia.com/shows/Subscribe for free to MuellerSheWrote on Substackhttps://muellershewrote.substack.comFollow AG and Dana on Social MediaDr. Allison Gill Substack|Muellershewrote, BlueSky|@muellershewrote , Threads|@muellershewrote, TikTok|@muellershewrote, IG|muellershewrote, Twitter|@MuellerSheWrote,Dana GoldbergTwitter|@DGComedy, IG|dgcomedy, facebook|dgcomedy, IG|dgcomedy, danagoldberg.com, BlueSky|@dgcomedyHave some good news; a confession; or a correction to share?Good News & Confessions - The Daily Beanshttps://www.dailybeanspod.com/confessional/ Listener Survey:http://survey.podtrac.com/start-survey.aspx?pubid=BffJOlI7qQcF&ver=shortFollow the Podcast on Apple:The Daily Beans on Apple PodcastsWant to support the show and get it ad-free and early?Supercasthttps://dailybeans.supercast.com/Patreon https://patreon.com/thedailybeansOr subscribe on Apple Podcasts with our affiliate linkThe Daily Beans on Apple Podcasts

My guest is Dr. Jay Bhattacharya, MD, PhD, Director of the National Institutes of Health (NIH) and Professor Emeritus of Health Policy at Stanford University. We discuss which scientific questions ought to be the priority for NIH, how to incentivize bold, innovative science especially from younger labs, how to solve the replication crisis and restore trust and transparency in science and public health, including acknowledging prior failures by the NIH. We discuss the COVID-19 pandemic and the data and sociological factors that motivated lockdowns, masking and vaccine mandates. Dr. Bhattacharya shares his views on how to resolve the vaccine–autism debate and how best to find the causes and cures for autism and chronic diseases. The topics we cover impact everyone: male, female, young and old and, given that NIH is the premier research and public health organization in the world, extend to Americans and non-Americans alike. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Levels: ⁠https://levels.link/huberman⁠ LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Jay Bhattacharya 00:06:56 National Institutes of Health (NIH), Mission 00:09:12 Funding, Basic vs. Applied Research 00:18:22 Sponsors: David & Eight Sleep 00:21:20 Indirect Costs (IDC), Policies & Distribution 00:30:43 Taxpayer Funding, Journal Access, Public Transparency 00:38:14 Taxpayer Funding, Patents; Drug Costs in the USA vs Other Countries 00:48:50 Reducing Medication Prices; R&D, Improving Health 01:00:01 Sponsors: AG1 & Levels 01:02:55 Lowering IDC?, Endowments, Monetary Distribution, Scientific Groupthink 01:12:29 Grant Review Process, Innovation 01:21:43 R01s, Tenure, Early Career Scientists & Novel Ideas 01:31:46 Sociology of Grant Evaluation, Careerism in Science, Failures 01:39:08 “Sick Care” System, Health Needs 01:44:01 Sponsor: LMNT 01:45:33 Incentives in Science, H-Index, Replication Crisis 01:58:54 Scientists, Data Fraud, Changing Careers 02:03:59 NIH & Changing Incentive Structure, Replication, Pro-Social Behavior 02:15:26 Scientific Discovery, Careers & Changing Times, Journals & Publications 02:19:56 NIH Grants & Appeals, Under-represented Populations, DEI 02:28:58 Inductive vs Deductive Science; DEI & Grants; Young Scientists & NIH Funding 02:39:38 Grant Funding, Identity & Race; Shift in NIH Priorities 02:51:23 Public Trust & Science, COVID Pandemic, Lockdowns, Masks 03:04:41 Pandemic Mandates & Economic Inequality; Fear; Public Health & Free Speech 03:13:39 Masks, Harms, Public Health Messaging, Uniformity, Groupthink, Vaccines 03:22:48 Academic Ostracism, Public Health Messaging & Opposition 03:30:26 Culture of American Science, Discourse & Disagreement 03:36:03 Vaccines, COVID Vaccines, Benefits & Harms 03:47:05 Vaccine Mandates, Money, Public Health Messaging, Civil Liberties 03:54:52 COVID Vaccines, Long-Term Effects; Long COVID, Vaccine Injury, Flu Shots 04:06:47 Do Vaccines Cause Autism?; What Explains Rise in Autism 04:18:33 Autism & NIH; MAHA & Restructuring NIH? 04:25:47 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

"It is a scientific fact that these macaques, like all other primates, including humans, are communicating. They communicate in much the same way we do - facial expressions, vocalizations, body postures, those kinds of things." - Jeff Kerr Jeff Kerr is PETA foundations Chief Legal Officer. I asked him to come on the show to talk about one of PETA's current lawsuits against the National Institutes of Health (NIH) and Nathional Institute of Mental Health (NIMH). PETA is arguing that the monkeys being tested on in a government run facility are capable of communication (or “are communicating”). And that we have a constitutional right under the First Amendment to receive their communications. This could be a game changer in allowing us to see what's really going on in labs that are funded by taxpayer money, and which have so far been censored from public view. PETA's lawsuit follows years of NIH's attempts to deny Freedom of Information requests banning PETA executives from its campus and illegally censoring animal advocates' speech on NIH's public social media pages. Through the lawsuit, PETA is seeking a live audio-visual feed to see and hear real-time communications from the macaques who have been kept isolated, used in fear experiments, and had posts cemented into their heads. Anthropologists and other scientists have studied macaque and other primate communications for decades and know that the monkeys communicate effectively and intentionally through lip smacking, fear grimaces, body language, and various cries and sounds—all of which constitute speech under the law. Primatologists can analyze that speech on a deeper level to share their stories with the world.

Vaccination is one of the best ways to prevent diseases. Over the past 50 years, essential vaccines saved at least 154 million lives (1). During the same period, vaccination has reduced infant deaths by 40%. Together with governments, vaccine manufacturers, scientists and medical experts, WHO's vaccine safety program is constantly helping monitor the safety of vaccines. This helps ensure that vaccines are safe for you and your family. ​In the United States, a number of safeguards are required by law to help ensure that the vaccines we receive are safe. Because vaccines are given to millions of healthy people—including children—to prevent serious diseases, they're held to very high safety standards. Every authorized or approved vaccine goes through safety testing, including: Testing and evaluation of the vaccine before it's licensed by the Food and Drug Administration (FDA) and recommended for use by the Centers for Disease Control and Prevention (CDC) Monitoring the vaccine's safety after it is recommended for infants, children, or adults ​ Before a vaccine is ever recommended for use, it's tested in labs. This process can take several years. FDA uses the information from these tests to decide whether to test the vaccine with people. During a clinical trial, a vaccine is tested on people who volunteer to get vaccinated. Clinical trials usually start with 20 to 100 volunteers, but eventually include thousands of volunteers. These tests can take several years and answer important questions like: Is the vaccine safe? What dose (amount) works best? How does the immune system react to it? Throughout the process, FDA works closely with the company producing the vaccine to evaluate the vaccine's safety and effectiveness. All safety concerns must be addressed before FDA licenses or authorizes a vaccine. ​Once a vaccine is approved or authorized, it continues to be tested. The company that makes the vaccine tests batches to make sure the vaccine is: Potent (It works like it's supposed to) Pure (Certain ingredients used during production have been removed) Sterile (It doesn't have any outside germs) FDA reviews the results of these tests and inspects the factories where the vaccine is made. This helps make sure the vaccines meet standards for both quality and safety. ​Once a vaccine is recommended for use, FDA, CDC, and other federal agencies continue to monitor its safety. ​The United States has one of the most advanced systems in the world for tracking vaccine safety. Each of the systems below supplies a different type of data for researchers to analyze. Together, they help provide a full picture of vaccine safety. Vaccine Adverse Events Reporting System (VAERS): VAERS is an early warning system managed by CDC and FDA that is designed to find possible vaccine safety issues. Patients, health care professionals, vaccine companies, and others can use VAERS to report side effects that happen after a patient received a vaccine. Some side effects might be related to vaccination while others might be a coincidence (happen by chance). VAERS helps track unusual or unexpected patterns of reporting that could mean there's a possible vaccine safety issue that needs further evaluation. The Vaccine Safety Datalink (VSD): VSD is a collaboration between CDC and several health care organizations across the nation. VSD uses databases of medical records to track vaccine safety and do research in large populations. By using medical records instead of self-reports, VSD can quickly study and compare data to find out if reported side effects are linked to a vaccine. Post-licensure Rapid Immunization Safety Monitoring System (PRISM), links to an external website, opens in a new tab: PRISM is part of the Sentinel Initiative, which is FDA's national system for monitoring medical products after they're licensed for use. PRISM focuses on vaccine safety—it uses a database of health insurance claims to identify and evaluate possible safety issues for licensed vaccines. Clinical Immunization Safety Assessment Project (CISA): CISA is a collaboration between CDC and a national network of vaccine safety experts from medical research centers. CISA does clinical vaccine safety research and—at the request of providers—evaluates complex cases of possible vaccine side effects in specific patients. Biologics Effectiveness and Safety (BEST) System: A system that uses multiple data sources and rapid queries to detect or evaluate adverse events or study specific safety questions. Additional research and testing: The Department of Defense (DoD), the U.S. Department of Veterans Affairs (VA), and the Indian Health Service (IHS) have systems to monitor vaccine safety and do vaccine safety research. The National Institutes of Health (NIH) and the Office of Infectious Disease and HIV/AIDS Policy (OIDP) also support ongoing research on vaccines and vaccine safety. During emergencies, such as the COVID-19 pandemic, additional safety activities are utilized to help evaluate the data in quickly and with special populations. For example, a new smartphone tool called V-safe uses text messaging and surveys to check in with COVID-19 vaccine recipients after vaccination.  (CREDITS)   

My guest is Dr. Christopher Gardner, Ph.D., professor of medicine and director of nutrition studies at Stanford. He is known for his pioneering research on the impact of dietary interventions on weight loss and health. We compare ketogenic, vegetarian, vegan and omnivorous diets—and why there is no one-size-fits-all approach. All agree, however, that eliminating or dramatically reducing processed foods is best for health. We discuss the protein needs controversy; plant vs. animal proteins; the importance of fiber and low-sugar fermented foods for gut health and inflammation; and how diet affects gene expression. We also review food allergies—including gluten, wheat, dairy and soy—as well as raw dairy. The episode offers data-supported advice for healthier eating. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Mateina: https://drinkmateina.com/huberman BetterHelp: https://betterhelp.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levelshealth.com/huberman Timestamps 00:00:00 Christopher Gardner 00:02:32 Is there a Best Diet?, Individual Needs, Geography & Diet, Lactose 00:11:02 Sponsors: Eight Sleep & Mateina 00:13:49 Raw Milk, Lactose Intolerance 00:20:33 Wheat Allergies, Gluten Intolerance; Celiac Disease 00:25:12 Processed Foods, Food Dyes, Research Outcomes, NOVA Classification, GRAS 00:33:44 Processed Foods, Economic & Time Considerations, US vs European Products 00:39:59 Food Industry Funding, Investigator Influence, Equipoise, Transparency 00:50:10 Sponsors: AG1 & BetterHelp 00:53:11 Industry Funding, National Institute of Health (NIH) 00:56:41 Whole Food, Plant-Based Diet; Diet Comparison, DIETFITS, A TO Z Study 01:10:24 Nutrition Naming, Omnivore, Meat, Animal Feeding Operations (CAFO) 01:17:14 Transforming American Diet; Taste, Health & Environment 01:22:26 Sponsor: LMNT 01:23:43 Food Preparation, Chefs, Improve School Food 01:29:54 Scalability, Mega-Farms, Small Farm & Farmer Loss 01:34:25 Protein Requirements, Dietary Protein Recommendations, Standard Deviations 01:45:33 Protein & Storage 01:52:12 Plants & Complete Proteins?, Legumes, Bioavailability 02:01:58 Sponsor: Levels 02:03:17 Beyond Meat, Impossible Meat, Ingredients, Sourcing Meat, Salt 02:09:18 Vegan vs Omnivore Diet, Twin Study, Cardiometabolic Markers, Genes, Microbiome 02:20:24 Health Science Communication, DEXA; “Protein Flip” Diet; Food Patterns, Caloric Intake 02:31:29 Microbiome, Inflammation, Fiber, Tool: Low-Sugar, Fermented Food 02:45:32 Acknowledgements 02:47:55 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures

Governor Patrick Morrisey of West Virginia discusses his initiatives to improve health, including the "Four Pillars of Healthy West Virginia" focusing on food cleanliness, work incentives, daily exercise, and healthy food choices. He highlights the "Mountaineer Mile" initiative, encouraging daily walks, and the "SNAP" program's shift to promote nutritious food. Morrisey also emphasizes West Virginia's microgrid movement, aiming to attract data centers and reduce income taxes through new developments. Additionally, he mentions the state's ban on Red Dye Number 3 in food and the Riley Gaines Act, which defines sex-based terms in sports, protecting women's sports.Additionally, Utah State Representative Trevor Lee sheds light on the state's progressive legislative actions, including a groundbreaking bill to ban certain flags from government buildings and the push for gold as a transactional currency.Finally, Dr. Isaiah Hankel, a former NIH-funded researcher and CEO of Overqualified.com. Dr. Hankel shares his insights on the corruption and lack of accountability within the National Institutes of Health (NIH), discussing how research priorities often overshadow human safety. He highlights alarming statistics about the reproducibility of scientific studies and the opaque nature of funding and oversight.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this Podcast Extra, we hear the latest on how decisions by the Trump administration are affecting science in the US. Most recently, a purge of National Institutes of Health (NIH) leadership has seen the chiefs of multiple institutes and centres removed from their posts.Plus, after cancelling nearly all NIH projects studying transgender health, the White House has directed the agency to focus on studying “regret” after a person transitions to align their body with their gender identity.News: ‘One of the darkest days': NIH purges agency leadership amid mass layoffsNews: Exclusive: Trump White House directs NIH to study ‘regret' after transgender people transitionNews: Are the Trump team's actions affecting your research? How to contact Nature Hosted on Acast. See acast.com/privacy for more information.

My guest is Dr. Chris Palmer, M.D., a board-certified psychiatrist and professor at Harvard Medical School. He explains how specific nutrition, exercise, supplement-based, and other factors can improve mitochondrial health and thereby provide relief from adult and childhood ADHD, bipolar disorder, schizophrenia, and symptoms of autism. We discuss mitochondrial biology, whether vaccines can impact inflammation and mitochondrial health, and the potential ramifications. We also review creatine, methylene blue, and urolithin A, as well as the role of B vitamins and iron in treating depression. By the end of this episode, you will understand the powerful link between metabolic health and mental health, and the lifestyle, dietary, and other factors you can leverage to help overcome common mental health challenges and disorders. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Our Place: https://fromourplace.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Dr. Chris Palmer 00:02:15 Integrating Metabolic, Mental & Physical Health; Childhood Trauma & Risk 00:10:46 Sponsors: Our Place & LMNT 00:13:44 Depression Causes, Molecule Model?, Neuroplasticity?; Metabolism 00:22:20 Mitochondrial Functions, Stress Response, Mental Health 00:31:09 Sponsors: AG1 & Eight Sleep 00:33:59 Mitochondrial Health & 6 Pillars of Lifestyle Medicine 00:39:38 Stimulants, Mitochondria, Dopamine; Alcohol 00:45:47 Nicotine; Substance Use, Metabolic Health & Disease 00:52:23 Children, Energy & Metabolic Function; Diseases of Aging & Mental Disorders 00:59:18 Sponsor: Function 01:01:06 Diet & Metabolism; Ultra-Processed Foods, Additives, GRAS 01:09:30 Rebellious Spirit, Ultra-Processed Foods & Food Industry Funding 01:19:14 Ketogenic Diet, Epilepsy, Schizophrenia, Bipolar 01:22:52 Ketogenic Diet, Fasting & Mitochondria; Gut Microbiome, Brain Metabolism 01:30:06 Low-Fat Diets; Tool: Occasional Fasts; Ketogenic Diet; Intermittent Fasting 01:38:40 Nutrition Research, Food Industry Lobbyists; Ultra-Processed Foods, Addiction 01:46:55 Creatine & Mitochondrial Health 01:52:34 Methylene Blue & Mitochondria; Serotonin Syndrome 02:02:58 Urolithin A, Mitochondria Function; Supplements & Appropriate Use 02:11:14 Vitamin Deficiencies, Iron Deficiency 02:16:06 Vitamin B12 & Folate Deficiency, Autoimmune Disorders 02:24:48 Mental Illness & Root Causes 02:29:02 Vaccines, Inflammation, Mitochondria, Autism 02:39:17 Neurodevelopmental Disorder Onset & Follow-Up 02:45:31 Vaccines, Autism, Future Research; Mother Obesity & Diabetes 02:51:23 Father Obesity & Autism; Poor Metabolic Health, Blood Biomarkers 02:56:44 Assessing Metabolic Health & Biomarkers; National Institutes of Health (NIH) 03:02:59 Future Directions, Bridging Mental & Physical Health 03:09:27 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures

Former NIH director Dr. Harold Varmus speaks out about what recent budget cuts and policy changes could mean for science.One of the areas targeted by President Trump's administration for cuts has been the National Institutes of Health (NIH). Cost-cutting actions have included the layoffs of some 1,200 NIH employees, the termination of research grants, a pause in the “study sections” that evaluate and award grant funding, and a cap on indirect costs included in research grants. Some of those moves have been paused following court cases. Dr. Harold Varmus, a former director of the National Institutes of Health, joins Host Ira Flatow to talk about the actions, and the impact he fears they could have on the future of biomedical research in the United States.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

The acting head of the NIH reportedly pushed back against legal guidance to resume grant funding, leaving federal workers in the lurch. Also, though fungi make up a tiny part of the human microbiome, they play an important role in both the prevention and development of many diseases.Cuts And Conflicting Directives Sow Confusion For NIH WorkersJust over a month after President Trump's inauguration, federal science in the US is in a state of disarray. Executive orders to halt grant funding at the National Institutes of Health (NIH) have faced court challenges. Last week, a federal judge extended a restraining order on a proposal to cap NIH grant funding for indirect costs, costs that experts say are critical to their work. But according to new reporting, staff within the NIH have been left without clear guidance about moving forward with those grants, with the NIH's acting director reportedly pushing back against legal guidance from the agency's lawyers to restart distribution of the funding.Host Flora Lichtman is joined by Katherine J. Wu, staff writer for The Atlantic, who reported on the turmoil at the NIH. They also talk about other science news of the week, including an update on the measles outbreak in Texas, how to see every planet in the solar system this week, and how scientists think runner Faith Kipeygon could be the first woman to break a four-minute mile.You've Heard Of The Microbiome—Welcome To The MycobiomeYou've heard of the microbiome, the community of bacteria, viruses, archaea parasites, and fungi that live in our bodies. But that last member of the group, fungi, get a lot less attention than the others. And perhaps that's unsurprising. After all, bacteria outnumber fungi 999 to 1 in our guts.But now, scientists are beginning to piece together just how important fungi truly are. Disruption in the fungal balance can play a role in the development of Crohn's disease, irritable bowel disease, celiac disease, colorectal cancer, some skin diseases, and more.Host Flora Lichtman talks with Dr. Mahmoud Ghannoum, microbiologist and professor at Case Western Reserve University's School of Medicine, who has dedicated his career to studying the fungi in our bodies, and coined the term mycobiome over a decade ago.Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.