Podcasts about OpenAI

1/4: The Optimist: Sam Altman, OpenAI, and the Race to Invent the Future  by  Keach Hagey  (Author) 1966 DC

2/4:  The Optimist: Sam Altman, OpenAI, and the Race to Invent the Future  by  Keach Hagey  (Author) 1978 TINKER SSFB COMPUTER CENTER

3/4: The Optimist: Sam Altman, OpenAI, and the Race to Invent the Future  by  Keach Hagey  (Author) 1978 NETHERLANDS IBM 360/85

4/4: The Optimist: Sam Altman, OpenAI, and the Race to Invent the Future  by  Keach Hagey  (Author) 1980 IBM 370/145

Today's show: Grok 4 just leapfrogged OpenAI to become the top AI model—and it's not just hype. In this episode, @Jason and @alex break down Grok's AGI-level performance, the massive drop in LLM pricing, and why some companies are raising prices anyway. They also dive into the Missouri AG's investigation into AI “bias,” the future of First Amendment protections for LLMs, and how autonomous vehicles are creating a new category: “autonomous commerce.” If you're building with AI or betting on the future of tech, don't miss this one.Timestamps:(1:55) AI models: Grok 4 and performance benchmarks(3:51) Detailed analysis of AI model performance and price trends(10:11) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(11:25) AI models' problem-solving capabilities and timeline for solving math problems(16:53) Legal and regulatory challenges for AI(19:56) Retool - Visit https://www.retool.com/twist and try it out today.(21:12) Bias in AI models and political implications(30:41) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twist(32:07) Infinite energy potential and AI impact; Bitcoin's new high(37:11) Crypto regulation and fintech under new administration(45:50) Future of storage, computing power, and GPU lifespan in data centers(53:40) Claude segment by Anthropic(55:09) Guest Ben Seidl of Autolane introduction(57:19) Autolane's impact on autonomous vehicles and commerce(59:05) Rise of autonomous commerce and logistics(1:06:37) Retailer issues with autonomous vehicle integration and orchestrationSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:11) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(19:56) Retool - Visit https://www.retool.com/twist and try it out today.(30:41) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Box CEO Aaron Levie is back for our weekly discussion of the latest tech news. We cover: 1) OpenAi's Windsurf deal falls through 2) Is OpenAI okay? 3) What percentage of all AI spend goes to coding? 4) Google's AI code play 5) Grok 4 is out 6) Does Grok show the scaling laws are still in effect? 7) Would Box work with Grok? 8) NVIDIA hits $4 trillion 9) Are we in an AI bubble? 10) Should Tim Cook step down? 11) Could Apple merge with OpenAI? --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here's 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

Like it or not, more people are using artificial intelligence than ever. On this week's On the Media, hear about the AI arms race between the U.S. and China, and how the tech gets overhyped. Plus, a composer wrestles with a new AI music generator – which threatens his own job.[01:00] Brooke speaks with Ed Zitron, host of the Better Offline podcast and author of the newsletter Where's Your Ed At, about how tech moguls have gotten away with overhyping A.I. for years. Plus, the apparent race for AI supremacy between the U.S. and China.[18:09] Brooke continues the conversation with Ed Zitron, peeling back the facade to explore what generative A.I. can actually do.[29:51]  Former OTM producer, and current composer and sound designer, Mark Henry Phillips, on how AI music generators could fundamentally upend his industry for good.Further reading:“Deep Impact,” by Ed Zitron“Godot Isn't Making it,” by Ed Zitron“Bubble Trouble,” by Ed Zitron On the Media is supported by listeners like you. Support OTM by donating today (https://pledge.wnyc.org/support/otm). Follow our show on Instagram, Twitter and Facebook @onthemedia, and share your thoughts with us by emailing onthemedia@wnyc.org.

(0:00) The Besties welcome Travis Kalanick and Keith Rabois! (3:02) Travis on Pony.ai / Uber rumors and the state of Cloud Kitchens (18:51) xAI launches Grok 4, learning "The Bitter Lesson" in AI (40:36) How Grok can catch ChatGPT in usage, OpenAI's product excellence (46:27) Perplexity and OpenAI building AI-native browsers and taking on Chrome (58:01) Elon's "America Party": is now the right time for a third party, and could he make an impact in 2026? (1:13:12) SCOTUS backs Trump over federal government RIF plans Follow the Keith: https://x.com/rabois Follow the Travis: https://x.com/travisk Get The Besties All-In Tequila: https://tequila.allin.com Join us at the All-In Summit: https://allin.com/summit Summit scholarship application: http://bit.ly/4kyZqFJ Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on Instagram: https://www.instagram.com/theallinpod Follow on TikTok: https://www.tiktok.com/@theallinpod Follow on LinkedIn: https://www.linkedin.com/company/allinpod Intro Music Credit: https://rb.gy/tppkzl https://x.com/yung_spielburg Intro Video Credit: https://x.com/TheZachEffect Referenced in the show: https://www.nytimes.com/2025/06/26/technology/uber-travis-kalanick-self-driving-car-deal.html https://www.youtube.com/watch?v=ZW5fJikPmfM https://grok.com https://www.youtube.com/watch?v=_wTA90BYo30 https://techcrunch.com/2025/01/08/elon-musk-agrees-that-weve-exhausted-ai-training-data https://x.com/ArtificialAnlys/status/1943166841150644622 https://x.com/elonmusk/status/1943192643439337753 http://www.incompleteideas.net/IncIdeas/BitterLesson.html https://x.com/chamath/status/1943177837956968499 https://techcrunch.com/2025/07/09/perplexity-launches-comet-an-ai-powered-web-browser https://x.com/perplexity_ai/status/1942969263305671143 https://x.com/elonmusk/status/1941584569523732930 https://polymarket.com/event/will-elon-register-the-america-party-by https://ropercenter.cornell.edu/presidential-approval/highslows https://news.gallup.com/poll/651278/support-third-political-party-dips.aspx https://www.whitehouse.gov/presidential-actions/2025/02/implementing-the-presidents-department-of-government-efficiency-workforce-optimization-initiative https://www.scotusblog.com/2025/07/supreme-court-allows-trump-administration-to-implement-plans-to-significantly-reduce-the-federal-workforce https://www.afge.org/article/summary-of-afge-lawsuits-against-trump--how-litigation-works https://cei.org/publication/10kc-2025-numbers-of-rules https://www.netflix.com/tudum/articles/american-manhunt-osama-bin-laden-release-date-news

Summer phone season kicks off with Samsung's latest launch. Jake, Vee, and Allison talk about Samsung's new lineup of foldables, including the very thin new Z Fold 7 and Allison's disdain for the Z Flip 7 FE. Vee has impressions of Samsung's new Galaxy Watch 8 lineup and its squircle-y new redesign. Then, it's time to talk Big Tech shakeups. Apple's COO is leaving, Zuckerberg is buying himself an AI dream team, X's CEO is out — and its chatbot Grok is on a rampage. Finally, big things are in store for the Lightning Round… which shall henceforth be known as the THUNDER ROUND. Lots to talk about, including Lorde's CD problems, Apple's Liquid Glass changes, and HBO Max finally becoming HBO Max again. Further reading: Samsung Galaxy Unpacked 2025: Everything announced at the July event Galaxy Z Fold 7 hands-on: Samsung finally made the foldables we've been asking for  Samsung cuts price of its foldables with the Z Flip 7 FE Samsung Galaxy Watch 8 series hands-on: squircle squad Samsung seems to have leaked its own trifold phone design Samsung says its trifold phone should launch ‘this year' Samsung snuck a trifold tease into (January) Unpacked One of Tim Cook's possible successors is leaving Apple Sabih Khan Apple's design team will report to Tim Cook A close look at who could succeed Tim Cook Mark Zuckerberg announces his AI ‘superintelligence' super-group Meta is paying $14 billion to catch up in the AI race Meta's ‘superintelligence' hiring spree adds an AI leader from Apple Pay packages of up to $300 million over four years Meta is trying to win the AI race with money — but not everyone can be bought X CEO Linda Yaccarino is stepping down after two years X's CEO is out after failing at basically everything she claimed she wanted Threads is catching up to X on mobile X has a new head of product Elon Musk's xAI buys Elon Musk's X for $33 billion on paper xAI updated Grok to be more ‘politically incorrect' Grok stops posting text after flood of antisemitism and Hitler praise “In other posts it referred to itself as “MechaHitler”. Musk makes grand promises about Grok 4 in the wake of a Nazi chatbot meltdown Adobe's new camera app is making me rethink phone photography Ikea's latest speaker lamp ditches Sonos for Spotify and inexpensive Bluetooth Ikea ditches Zigbee for Thread going all in on Matter smart homes Perplexity launches Comet web browser OpenAI's next big launch could be an AI web browser E Ink is turning the laptop touchpad into an e-reader for AI apps Lorde's new CD is so transparent that stereos can't even read it I tried playing Lorde's new CD Appeals court strikes down ‘click-to-cancel' rule Nothing's ‘first true flagship' phone plays it a little safe Adding calendar events with a screenshot is AI at its finest The government's Apple antitrust lawsuit is still on Apple just added more frost to its Liquid Glass design Apple's second-generation Vision Pro might launch this year Nvidia briefly became the first $4 trillion company on Wednesday The makers of Cameo just launched... a birthday-tracking app? Nintendo is ending its cost-saving Switch game vouchers HBO Max is officially HBO Max again Email us at vergecast@theverge.com or call us at 866-VERGE11, we love hearing from you. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Welcome to The Chopping Block – where crypto insiders Haseeb Qureshi, Tom Schmidt, Tarun Chitra, and Robert Leshner chop it up about the latest in crypto. In this episode, the gang is joined by Paul Grewal, Chief Legal Officer at Coinbase, for a wide-ranging conversation on crypto's next big frontier: tokenized stocks. From Robinhood's controversial attempt to tokenize SpaceX and OpenAI shares to the legal and structural hurdles around pre-IPO derivatives, the crew dives deep into what it really takes to bring Wall Street on-chain. They also unpack the regulatory momentum behind the Genius and Clarity Acts, the return of ICO mania with Pump.fun's $1B token raise, and the absurdly viral drama of Suitgate on Polymarket. Is this a new era of regulated innovation—or are we just recreating old problems on new rails? Tune in for sharp takes, legal insight, and a few laughs along the way. Show highlights

On this episode of "Right About Now with Ryan Alford," Ryan covers five major business stories, including looming 25% tariffs on tech imports from China and South Korea, the anticipated launch of OpenAI's GPT-5 and its impact on the AI industry, and insights from guest Matt Britton on AI-driven changes in hardware, creativity, and coding. The episode also discusses talent competition among tech giants, Amazon Prime Day's retail shakeup, and the latest Federal Reserve rate outlook. Listeners get sharp analysis on how these trends will shape business, technology, and everyday life.TAKEAWAYSPrice increase of 25% on tech products from China and South Korea due to tariffs.Upcoming release of GPT-5 by OpenAI and its potential impact on the AI landscape.Insights on the rapid evolution of AI and hardware development.The transformation of creativity and coding skills due to AI advancements.Talent acquisition trends in the tech industry, including poaching of top engineers.Amazon Prime Day sales and retail strategies to compete with online shopping.Federal Reserve's interest rate outlook and its implications for the market.The impact of AI on everyday life and the future of robotics.The consolidation of AI tools and its effects on business operations.The importance of adapting marketing strategies to consumer behavior and scarcity.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Kieran Flanagan is the CMO at HubSpot, where he's led the transformation of their growth strategy from SEO-led to multi-channel and AI-powered. Formerly SVP of Marketing, he helped scale HubSpot's user base to millions and revenue past $2B. Before HubSpot, he drove breakout growth at Marketo and Salesforce. Kieran is one of the most respected voices in SaaS marketing and a pioneer in growth-driven content strategy. Agenda: 00:03 – The Death of Growth Teams? Kieran's Wild Prediction 06:44 – AI Innovation Pods: The New Org Structure for Startups 10:18 – Email Personalization That Tripled Conversions 13:21 – From Software Budget to Labor Budget: The Shift is Happening 16:35 – The Big Lie: Why Autonomous Agents Still Suck 19:24 – The Secret Sauce Behind HubSpot's Email AI Stack 21:44 – Segment-Based Marketing Is Dead. Enter Micro Audiences. 24:15 – Content Collapse: Why Google Organic Is Getting Torched 30:52 – The Future of AI SEO: 1 Product, 100 Pages, Infinite Prompts 33:16 – Memory = Moat: Why ChatGPT Is Becoming Unbeatable 35:46 – Prompt Engineering is the New Coding: Here's How to Win 41:03 – The Death of the Middle Manager Marketer 46:17 – OpenAI vs. Anthropic: Kieran's $400M Bet 48:00 – Europe Is Falling Behind: The Harsh Truth on Regulation 52:39 – CMO Playbook 2025: Micro-Audiences, Creator-Led, AI at Scale    

This week Robert flies solo (Joe's busy revolutionizing dairy on the blockchain) to ask a question:  What if slower is the new smarter? After riffing on OpenAI's burnout‑induced shutdown, he unveils a sneak peek of his upcoming book, Valuable Friction. From Netflix's “Skip Intro” button to AI‑generated sameness, Robert shows how our obsession with frictionless everything is draining the meaning out of marketing...and life. Tune in for the four kinds of friction that sharpen ideas, deepen relationships, steady operations, and save you from knee‑jerk strategy. No co‑host, no fast‑forward, just 100 percent Robert. Press play, don't skip the intro, and discover why a little resistance might be your brand's unfair advantage. ----- This week's sponsor: You don't become the world's most valuable women's sports franchise by accident. Angel City Football Club did it with a little help from HubSpot. When they started, data was housed across multiple systems. HubSpot unified their website, email marketing, and fan experience in one platform. This allowed their small team of three to build an entire website in just three days. The results? Nearly 350 new sign-ups a week and 300% database growth in just two years. Visit https://www.hubspot.com/ to hear how HubSpot can help you grow better. ------- Liked this show? SUBSCRIBE to this podcast on Spotify, Apple, Google and more. Catch past episodes and show notes at ThisOldMarketing.com. Catch and subscribe to our NEW show on YouTube. NOTE: You can get captions there. Subscribe to Joe Pulizzi's Orangeletter and get two free downloads direct from Joe. Subscribe to Robert Rose's newsletter at Seventh Bear.

Grok 4 from xAI just aced “Humanity's Last Exam” benchmarks while Grok 3 had a catastrophic public meltdown. What does this mean for the future of AI and Elon Musk's credibility? And, in other AI news, OpenAI's GPT-5 is rumored to land next week along with a new open-source reasoning model, Google's DeepMind launches AI-designed drugs into human trials, and Perplexity's new AI browser Comet sparks OpenAI's plan to crush Chrome. PLUS YouTube cracks down on AI-generated spam while updating image-to-video in VEO 3, Moon Valley releases an “ethical” AI video platform, and why you should probably stop kicking robots. AI IS GETTING SMARTER...BUT WE STILL CONTROL THE TREATS. Join the discord: https://discord.gg/muD2TYgC8f Join our Patreon: https://www.patreon.com/AIForHumansShow AI For Humans Newsletter: https://aiforhumans.beehiiv.com/ Follow us for more on X @AIForHumansShow Join our TikTok @aiforhumansshow To book us for speaking, please visit our website: https://www.aiforhumans.show/   // Show Links //  Grok4: The Smartest Model Yet? https://x.com/xai/status/1943158495588815072    Elon Says Grok-4 is better than PhD Level… https://x.com/teslaownersSV/status/1943168634672566294   Benchmarks https://x.com/ArtificialAnlys/status/1943166841150644622 https://x.com/arcprize/status/1943168950763950555   McKay Wrigley Grok 4 Heavy Example https://x.com/mckaywrigley/status/1943385794414334032   Grok Goes Bad: The Unhinged Behavior https://www.nytimes.com/2025/07/08/technology/grok-antisemitism-ai-x.html https://www.npr.org/2025/07/09/nx-s1-5462609/grok-elon-musk-antisemitic-racist-content   X CEO Linda Yaccarino Quits https://www.cnbc.com/2025/07/09/linda-yaccarino-x-elon-musk.html   Elon still trying to fix answers  https://x.com/elonmusk/status/1943240153587421589   OpenAI Poaches Tesla/xAi People https://www.wired.com/story/openai-new-hires-scaling/   Apple's Top AI Exec Leaves For Meta https://x.com/markgurman/status/1942341725499863272   OpenAI's open-source model coming as soon as next week and compares to o3-mini https://www.theverge.com/notepad-microsoft-newsletter/702848/openai-open-language-model-o3-mini-notepad   Perplexity's Comet Browser Launches https://comet.perplexity.ai/   OpenAI Fires Back With Its Browser News https://x.com/AndrewCurran_/status/1943008960803680730   YouTube *Might* Change Their Policies to Limit Faceless AI Videos (and mass produced content) https://techcrunch.com/2025/07/09/youtube-prepares-crackdown-on-mass-produced-and-repetitive-videos-as-concern-over-ai-slop-grows/   Google VEO 3 Image-to-Vid launched https://x.com/Uncanny_Harry/status/1942686253817974984 https://x.com/CaptainHaHaa/status/1942907271841030183 https://x.com/TheoMediaAI/status/1942564887114166493   My test + ask for sound sampling from the team: https://x.com/AIForHumansShow/status/1942597607312040348   Moonvalley Launches AI Video Platform https://www.moonvalley.com/   GoogleDeepMinds's Isomorphic Labs Starts Human Trials on AI generated drugs https://www.aol.com/finance/google-deepmind-grand-ambitions-cure-130000934.html?utm_source=perplexity&guccounter=1   Noetix N2 Robot Endures Abuse From Its Developer https://x.com/TheHumanoidHub/status/1941935665173963085 https://noetixrobotics.com/products-138.html   Kavan The Kid (the AI Batman video guy) CRUSHED His New Original Trailer https://x.com/Kavanthekid/status/1940452444850589999   Reachy The Robot from Hugging Face https://x.com/Thom_Wolf/status/1942887160983466096   Autonomous Robot Excavator Building a Wall https://x.com/lukas_m_ziegler/status/1941815414683521488  

This week, we discuss the return of command line tools, Kubernetes embracing VMs, and the steady march of Windows. Plus, thoughts on TSA, boots, and the “old country." Watch the YouTube Live Recording of Episode (https://www.youtube.com/live/W0_6hPybAsQ?si=QfWLvts-ueyATxtz) 528 (https://www.youtube.com/live/W0_6hPybAsQ?si=QfWLvts-ueyATxtz) Runner-up Titles Pool Problems Stockholm Pool Syndrome The Old Country VMs aren't going anywhere Vaya con Dios This is why we have milk Why's he talking about forks? Commander Claude The Columbia Music House business plan Beat this horse into glue Reinvent Command Line “Man falls in love with CLI” Windows is always giving you the middle button CBT - Claude Behavioral Therapy. Rundown TSA tests security lines allowing passengers to keep their shoes on (https://www.washingtonpost.com/travel/2025/07/08/tsa-shoe-policy-airport-security/) KubeCon Is Starting To Sound a Lot Like VMCon (https://thenewstack.io/kubecon-is-starting-to-sound-a-lot-like-vmcon/?link_source=ta_bluesky_link&taid=6866ce8d6b59ab0001f28d23&utm_campaign=trueanthem&utm_medium=social&utm_source=bluesky) Claude Code and the CLI Gemini CLI: your open-source AI agent (https://blog.google/technology/developers/introducing-gemini-cli-open-source-ai-agent/) Cursor launches a web app to manage AI coding agents (https://techcrunch.com/2025/06/30/cursor-launches-a-web-app-to-manage-ai-coding-agents/) AI Tooling, Evolution and The Promiscuity of Modern Developers (https://redmonk.com/sogrady/2025/07/09/promiscuity-of-modern-developers/) Introducing OpenCLI (https://patriksvensson.se/posts/2025/07/introducing-open-cli) Windows Windows 11 has finally overtaken Windows 10 as the most used desktop OS (https://www.theverge.com/news/699161/microsoft-windows-11-usage-milestone-windows-10) Microsoft quietly implies Windows has LOST millions of users since Windows 11 debut — are people really abandoning ship? [UPDATE] (https://www.windowscentral.com/software-apps/windows-11/windows-11-10-lost-400-million-users-3-years) Relevant to your Interests Public cloud becomes a commodity (https://www.infoworld.com/article/4011196/public-cloud-becomes-a-commodity.html?utm_date=20250625131623&utm_campaign=InfoWorld%20US%20%20All%20Things%20Cloud&utm_content=slotno-1-title-Public%20cloud%20becomes%20a%20commodity&utm_term=Infoworld%20US%20Editorial%20Newsletters&utm_medium=email&utm_source=Adestra&aid=29276237&huid=) Nvidia Ruffles Tech Giants With Move Into Cloud Computing (https://www.wsj.com/tech/ai/nvidia-dgx-cloud-computing-28c49748?mod=hp_lead_pos11) Which Coding Assistants Retain Their Customers and Which Ones Don't (https://www.theinformation.com/articles/coding-assistants-retain-customers-ones?utm_source=ti_app&rc=giqjaz) Anthropic destroyed millions of print books to build its AI models (https://arstechnica.com/ai/2025/06/anthropic-destroyed-millions-of-print-books-to-build-its-ai-models/) Sam Altman upstages the critics (https://www.platformer.news/sam-altman-hard-fork-live/?ref=platformer-newsletter) The Ultimate Cloud Security Championship | 12 Months × 12 Challenges (https://cloudsecuritychampionship.com/) Denmark to tackle deepfakes by giving people copyright to their own features (https://www.theguardian.com/technology/2025/jun/27/deepfakes-denmark-copyright-law-artificial-intelligence) Why Automattic CEO Matt Mullenweg went to war over WordPress (https://overcast.fm/+AAQLdsK48uM) How Nintendo locked down the Switch 2's USB-C port and broke third-party docking (https://www.theverge.com/report/695915/switch-2-usb-c-third-party-docks-dont-work-authentication-encryption) CoreWeave to acquire Core Scientific in $9 billion all-stock deal (https://www.cnbc.com/2025/07/07/coreweave-core-scientific-stock-acquisition.html) Valve conquered PC gaming. What comes next? (https://www.ft.com/content/f4a13716-838a-43da-853b-7c31ac17192c) Datadog stock jumps 10% on tech company's inclusion in S&P 500 index (https://www.cnbc.com/2025/07/02/datadog-stock-jumps-sp-500-index-inclusion.html) Jack Dorsey just released a Bluetooth messaging app that doesn't need the internet (https://www.engadget.com/apps/jack-dorsey-just-released-a-bluetooth-messaging-app-that-doesnt-need-the-internet-191023870.html) Unlock the Full Chainguard Containers Catalog – Now with a Catalog Pricing Option (https://www.chainguard.dev/unchained/unlock-the-full-chainguard-containers-catalog-now-with-a-catalog-pricing-option) Oracle stock jumps after $30 billion annual cloud deal revealed in filing (https://www.cnbc.com/2025/06/30/oracle-orcl-stock-cloud-deal.html) Docker State of App Dev: AI (https://www.docker.com/blog/docker-state-of-app-dev-ai/) X Chief Says She Is Leaving the Social Media Platform (https://www.nytimes.com/2025/07/09/technology/linda-yaccarino-x-steps-down.html) Meta's recruiting blitz claims three OpenAI researchers (https://techcrunch.com/2025/06/25/metas-recruiting-blitz-claims-three-openai-researchers/) OpenAI Reportedly Shuts Down for a Week as Zuck Poaches Its Top Talent (https://gizmodo.com/openai-reportedly-shuts-down-for-a-week-as-zuck-poaches-its-top-talent-2000622145?utm_source=tldrnewsletter) OpenAI Leadership Responds to Meta Offers: ‘Someone Has Broken Into Our Home' (https://www.wired.com/story/openai-meta-leadership-talent-rivalry/) Sam Altman Slams Meta's AI Talent-Poaching Spree: ‘Missionaries Will Beat Mercenaries' (https://www.wired.com/story/sam-altman-meta-ai-talent-poaching-spree-leaked-messages/) Report: Apple looked into building its own AWS competitor (https://9to5mac.com/2025/07/03/report-apple-looked-into-building-its-own-aws-competitor/) Cloudflare launches a marketplace that lets websites charge AI bots for scraping (https://techcrunch.com/2025/07/01/cloudflare-launches-a-marketplace-that-lets-websites-charge-ai-bots-for-scraping/) The Open-Source Software Saving the Internet From AI Bot Scrapers (https://www.404media.co/the-open-source-software-saving-the-internet-from-ai-bot-scrapers/) Nonsense After 8 years of playing D&D nonstop, I've finally tried its biggest alternative (https://www.polygon.com/tabletop-games/610875/dnd-alternative-dungeon-crawl-classics-old-school) TSA tests security lines allowing passengers to keep their shoes on (https://www.washingtonpost.com/travel/2025/07/08/tsa-shoe-policy-airport-security/) Conferences Sydney Wizdom Meet-Up (https://www.wiz.io/events/sydney-wizdom-meet-up-aug-2025), Sydney, August 7. Matt will be there. SpringOne (https://www.vmware.com/explore/us/springone?utm_source=organic&utm_medium=social&utm_campaign=cote), Las Vegas, August 25th to 28th, 2025. See Coté's pitch (https://www.youtube.com/watch?v=f_xOudsmUmk). Explore 2025 US (https://www.vmware.com/explore/us?utm_source=organic&utm_medium=social&utm_campaign=cote), Las Vegas, August 25th to 28th, 2025. See Coté's pitch (https://www.youtube.com/shorts/-COoeIJcFN4). SREDay London (https://sreday.com/2025-london-q3/), Coté speaking, September 18th and 19th. Civo Navigate London (https://www.civo.com/navigate/london/2025), Coté speaking, September 30th. Texas Linux Fest (https://2025.texaslinuxfest.org), Austin, October 3rd to 4th. CFP closes August 3rd (https://www.papercall.io/txlf2025). CF Day EU (https://events.linuxfoundation.org/cloud-foundry-day-europe/), Frankfurt, October 7th, 2025. AI for the Rest of Us (https://aifortherestofus.live/london-2025), Coté speaking, October 15th to 16th, London. SDT News & Community Join our Slack community (https://softwaredefinedtalk.slack.com/join/shared_invite/zt-1hn55iv5d-UTfN7mVX1D9D5ExRt3ZJYQ#/shared-invite/email) Email the show: questions@softwaredefinedtalk.com (mailto:questions@softwaredefinedtalk.com) Free stickers: Email your address to stickers@softwaredefinedtalk.com (mailto:stickers@softwaredefinedtalk.com) Follow us on social media: Twitter (https://twitter.com/softwaredeftalk), Threads (https://www.threads.net/@softwaredefinedtalk), Mastodon (https://hachyderm.io/@softwaredefinedtalk), LinkedIn (https://www.linkedin.com/company/software-defined-talk/), BlueSky (https://bsky.app/profile/softwaredefinedtalk.com) Watch us on: Twitch (https://www.twitch.tv/sdtpodcast), YouTube (https://www.youtube.com/channel/UCi3OJPV6h9tp-hbsGBLGsDQ/featured), Instagram (https://www.instagram.com/softwaredefinedtalk/), TikTok (https://www.tiktok.com/@softwaredefinedtalk) Book offer: Use code SDT for $20 off "Digital WTF" by Coté (https://leanpub.com/digitalwtf/c/sdt) Sponsor the show (https://www.softwaredefinedtalk.com/ads): ads@softwaredefinedtalk.com (mailto:ads@softwaredefinedtalk.com) Recommendations Brandon: Park ATX Free Parking Codes (https://www.austintexas.gov/page/park-atx): FREE15ATX1 and FREE15ATX2 Matt: Careless People (https://en.wikipedia.org/wiki/Careless_People) Coté: Wizard Zines bundle (https://wizardzines.com/zines/all-the-zines/), Julia Evans. 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Fri, 11 Jul 2025 18:45:00 GMT http://relay.fm/material/524 http://relay.fm/material/524 Andy Ihnatko and Florence Ion Samsung unpacked its expensive new foldables. Perplexity and OpenAI are coming for Google's AI-powered search. Samsung unpacked its expensive new foldables. Perplexity and OpenAI are coming for Google's AI-powered search. clean 3757 Samsung unpacked its expensive new foldables. Perplexity and OpenAI are coming for Google's AI-powered search. This episode of Material is sponsored by: Vitally: A new era for customer success productivity. Get a free pair of AirPods Pro when you book a qualified meeting. Links and Show Notes: Hands On with Samsung's Satisfying-to-Shut Galaxy Z Flip 7 Hands On with the Samsung Galaxy Z Fold 7: The Ultimate Foldable for Your Wallet Don't Forget the Samsung Galaxy Watch 8 and Galaxy Watch 8 Classic Samsung's Now Brief Still Serves Bad Headlines Dive deeper with AI Mode and get gaming help in Circle to Search Nvidia-backed Perplexity launches AI-powered browser to take on Google Chrome Exclusive: OpenAI to release web browser in challenge to Google Chrome Suppo

Speak (https://speak.com) may not be very well known to native English speakers, but they have come from a slow start in 2016 to emerge as one of the favorite partners of OpenAI, with their Startup Fund leading and joining their Series B and C as one of the new AI-native unicorns, noting that “Speak has the potential to revolutionize not just language learning, but education broadly”. Today we speak with Speak's CTO, Andrew Hsu, on the journey of building the “3rd generation” of language learning software (with Rosetta Stone being Gen 1, and Duolingo being Gen 2). Speak's premise is that speech and language models can now do what was previously only possible with human tutors—provide fluent, responsive, and adaptive instruction—and this belief has shaped its product and company strategy since its early days. https://www.linkedin.com/in/adhsu/ https://speak.com One of the most interesting strategic decisions discussed in the episode is Speak's early focus on South Korea. While counterintuitive for a San Francisco-based startup, the decision was influenced by a combination of market opportunity and founder proximity via a Korean first employee. South Korea's intense demand for English fluency and a highly competitive education market made it a proving ground for a deeply AI-native product. By succeeding in a market saturated with human-based education solutions, Speak validated its model and built strong product-market fit before expanding to other Asian markets and eventually, globally. The arrival of Whisper and GPT-based LLMs in 2022 marked a turning point for Speak. Suddenly, capabilities that were once theoretical—real-time feedback, semantic understanding, conversational memory—became technically feasible. Speak didn't pivot, but rather evolved into its second phase: from a supplemental practice tool to a full-featured language tutor. This transition required significant engineering work, including building custom ASR models, managing latency, and integrating real-time APIs for interactive lessons. It also unlocked the possibility of developing voice-first, immersive roleplay experiences and a roadmap to real-time conversational fluency. To scale globally and support many languages, Speak is investing heavily in AI-generated curriculum and content. Instead of manually scripting all lessons, they are building agents and pipelines that can scaffold curriculum, generate lesson content, and adapt pedagogically to the learner. This ties into one of Speak's most ambitious goals: creating a knowledge graph that captures what a learner knows and can do in a target language, and then adapting the course path accordingly. This level-adjusting tutor model aims to personalize learning at scale and could eventually be applied beyond language learning to any educational domain. Finally, the conversation touches on the broader implications of AI-powered education and the slow real-world adoption of transformative AI technologies. Despite the capabilities of GPT-4 and others, most people's daily lives haven't changed dramatically. Speak sees itself as part of the generation of startups that will translate AI's raw power into tangible consumer value. The company is also a testament to long-term conviction—founded in 2016, it weathered years of slow growth before AI caught up to its vision. Now, with over $50M ARR, a growing B2B arm, and plans to expand across languages and learning domains, Speak represents what AI-native education could look like in the next decade. Chapters 00:00:00 Introductions & Thiel Fellowship Origins 00:02:13 Genesis of Speak: Early Vision & Market Focus 00:03:44 Building the Product: Iterations and Lessons Learned 00:10:59 AI's Role in Language Learning 00:13:49 Scaling Globally & B2B Expansion 00:16:30 Why Korea? Localizing for Success 00:19:08 Content Creation, The Speak Method, and Engineering Culture 00:23:31 The Impact of Whisper and LLM Advances 00:29:08 AI-Generated Content & Measuring Fluency 00:35:30 Personalization, Dialects, and Pronunciation 00:39:38 Immersive Learning, Multimodality, and Real-Time Voice 00:50:02 Engineering Challenges & Company Culture 00:53:20 Beyond Languages: B2B, Knowledge Graphs, and Broader Learning 00:57:32 Fun Stories, Lessons, and Reflections 01:02:03 Final Thoughts: The Future of AI Learning & Slow Takeoff

Fri, 11 Jul 2025 18:45:00 GMT http://relay.fm/material/524 http://relay.fm/material/524 Antioxidant Index 524 Andy Ihnatko and Florence Ion Samsung unpacked its expensive new foldables. Perplexity and OpenAI are coming for Google's AI-powered search. Samsung unpacked its expensive new foldables. Perplexity and OpenAI are coming for Google's AI-powered search. clean 3757 Samsung unpacked its expensive new foldables. Perplexity and OpenAI are coming for Google's AI-powered search. This episode of Material is sponsored by: Vitally: A new era for customer success productivity. Get a free pair of AirPods Pro when you book a qualified meeting. Links and Show Notes: Hands On with Samsung's Satisfying-to-Shut Galaxy Z Flip 7 Hands On with the Samsung Galaxy Z Fold 7: The Ultimate Foldable for Your Wallet Don't Forget the Samsung Galaxy Watch 8 and Galaxy Watch 8 Classic Samsung's Now Brief Still Serves Bad Headlines Dive deeper with AI Mode and get gaming help in Circle to Search Nvidia-backed Perplexity launches AI-powered browser to take on Google Chrome Exclusive: OpenAI to release web browser in challenge to Google Chrome Support Materi

The Newcomer Podcast returns just in time to have Eric, Tom, and Madeline weigh in on Meta's audacious AI hiring spree. The tech giant has enticed researchers from OpenAI, Google DeepMind, and Anthropic with huge paydays in the hopes it can bring its Llama models up to par with the competition. Next up, Ramp's report that companies have stopped purchasing AI tools made a lot of buzz this week, but it's still too early to call an AI peak.Later on in the episode, Grok's offensive replies aren't enough to slow down xAI's latest model launch. We close out the episode rehashing Sequoia partner Shaun Maguire's latest inflammatory tweets over New York mayoral candidate Zohran Mamdani.00:35 — Meta poaches top researchers to ail its flailing models11:13 — XAI outperforms despite Grok's offensive replies18:27 — It's too early to call the AI bubble28:50 — Shaun Maguire's tweets bring attention to Sequoia

Dan Moren joins us this week! Rumors are circulating about an A18 MacBook Pro and iPhone 17 Air from Apple, Samsung just held its Galaxy Unpacked event this month and unveiled updates to some of its products, AI bots are scraping obituaries for profit, and a new browser war is emerging between two AI companies. Dan Moren talks about the rumored A18 MacBook Pro and iPhone 17 Air that Apple could announce this year as ways to appeal to broader consumer markets. Mikah Sargent shares the Galaxy Z Flip7, Galaxy Z Fold7, and the Galaxy Watch8 that Samsung unveiled at its recently held Galaxy Unpacked July 2025 event. Joe Supan of CNET joins the show to talk with Mikah about how AI is starting to scrape obituaries shared on social media networks like Facebook, and is being monetized for profit. And Mikah discusses an upcoming AI-powered browser war that looks to challenge Google Chrome, with companies like Perplexity launching Comet and OpenAI soon to launch its own web browser. Hosts: Mikah Sargent and Dan Moren Guest: Joe Supan Download or subscribe to Tech News Weekly at https://twit.tv/shows/tech-news-weekly. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: go.acronis.com/twit uscloud.com

After a year of speculation and shifting narratives, GPT-5 appears to be nearing release—and it could be OpenAI's most ambitious model yet. In this episode, NLW breaks down everything we know about GPT-5: how it integrates OpenAI's reasoning and multimodal capabilities into a single, unified model; what rumors are swirling around features like longer context windows, memory, and mixture-of-experts architecture; and why this release may matter more for average users than hardcore AI insiders. Plus, what the rising pressure from Meta and OpenAI's internal challenges signal about the stakes of this next launch.Get Ad Free AI Daily Brief: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://patreon.com/AIDailyBrief⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Brought to you by:KPMG – Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://kpmg.com/ai⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to learn more about how KPMG can help you drive value with our AI solutions.Blitzy.com - Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://blitzy.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to build enterprise software in days, not months AGNTCY - The AGNTCY is an open-source collective dedicated to building the Internet of Agents, enabling AI agents to communicate and collaborate seamlessly across frameworks. Join a community of engineers focused on high-quality multi-agent software and support the initiative at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠agntcy.org ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Vanta - Simplify compliance - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://vanta.com/nlw⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Plumb - The automation platform for AI experts and consultants ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://useplumb.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Agent Readiness Audit from Superintelligent - Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://besuper.ai/ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠to request your company's agent readiness score.The AI Daily Brief helps you understand the most important news and discussions in AI. Subscribe to the podcast version of The AI Daily Brief wherever you listen: https://pod.link/1680633614Subscribe to the newsletter: https://aidailybrief.beehiiv.com/Join our Discord: https://bit.ly/aibreakdownInterested in sponsoring the show? nlw@breakdown.network

Agenda: [00:00] The AI Talent Crisis No One's Ready For [03:00] Daniel Gross and Nat Friedman: Why Two Legendary VCs Walked Away From $1B to Join Meta [12:00] Meta's AI Talent Magnet: Will It Actually Work? [15:00] Cursor Is Breaking the Market: Can Anyone Compete? [18:30] OpenAI's SBC Bombshell: More Stock Comp Than Revenue [22:00] CoreWeave's Power Play: Buying Their Landlords [26:00] Is Circle Next to Go Shopping with Meme Equity? [28:00] PE Is Back: The Olo Take-Private Explained [35:00] Why Triple, Triple, Double, Double Is No Longer Sexy [41:00] QSBS Hack: The Billionaire's Tax Loophole You're Missing [48:00] Microsoft's AI Layoffs: Salespeople Are Dead, Long Live Engineers [50:00] “If You Need a Week to Learn AI, You Should Be Fired” [53:00] Will Sequoia's Sean Maguire Be Pushed Out? Place Your Bets [57:00] Will There Be a Recession in 2025? Jason Bets $75K It's a No [1:00:00] Is Linda Yaccarino Still CEO of X by Year-End? [1:03:00] Circle and CoreWeave's Meme Rally: Real or Mirage?  

Is Cloudflare positioning itself as the new Sheriff in town when it comes to AI bots scraping sites? Intel admits it's further behind its competitors in fab and AI technologies. After catching OpenAI's bot telling users about a fake music notation feature, sheet music platform Soundslice built it. And YouTube is making changes to stop the spread of AI slop and plans on closing the platform's Trending section. Starring Robb Dunewood, Jenn Cutter, Roger Chang, Joe. To read the show notes in a separate page click here! Support the show on Patreon by becoming a supporter!

Dan Moren joins us this week! Rumors are circulating about an A18 MacBook Pro and iPhone 17 Air from Apple, Samsung just held its Galaxy Unpacked event this month and unveiled updates to some of its products, AI bots are scraping obituaries for profit, and a new browser war is emerging between two AI companies. Dan Moren talks about the rumored A18 MacBook Pro and iPhone 17 Air that Apple could announce this year as ways to appeal to broader consumer markets. Mikah Sargent shares the Galaxy Z Flip7, Galaxy Z Fold7, and the Galaxy Watch8 that Samsung unveiled at its recently held Galaxy Unpacked July 2025 event. Joe Supan of CNET joins the show to talk with Mikah about how AI is starting to scrape obituaries shared on social media networks like Facebook, and is being monetized for profit. And Mikah discusses an upcoming AI-powered browser war that looks to challenge Google Chrome, with companies like Perplexity launching Comet and OpenAI soon to launch its own web browser. Hosts: Mikah Sargent and Dan Moren Guest: Joe Supan Download or subscribe to Tech News Weekly at https://twit.tv/shows/tech-news-weekly. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: go.acronis.com/twit uscloud.com

In this episode of "Normal World," Dave Landau and Angela hold down the fort while 1/4 Black Garrett is out for the day. They break down the AI arms race between Elon Musk's Grok and OpenAI's ChatGPT — and why every tech company now wants a language model to shape your worldview. Is Grok really the “free speech” option or just Elon's unfiltered Twitter brain in chatbot form? And why did ChatGPT censor the term “illegal alien” but still let you role-play as a non-binary mushroom healer? They take aim at censorship, AI-driven speech policing, and the growing influence of tech companies over what people are allowed to say — or even think. From OpenAI's latest brand pivot to Apple's increasingly invasive device scans, they explore how generative AI might not just rewrite language but reshape reality. Then it gets personal, with stories about men falling in love with chatbots, cheating on their girlfriends with AI girlfriends, and even marrying an app — raising the question of whether AI is replacing human connection … or just mocking it. They also react to the TSA's new rule allowing passengers to board U.S. flights without removing their shoes. They pull up a photo of Hakeem Jeffries and react to just how weird it looks. Today's guest on "Normal World" is Mike Imbasciani, who performs his original song, “Methland Florida.” SPONSORS Lean- Brickhouse Nutrition Let's get you started with 20% off. Just use code NORMAL20 at www.takelean.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Dan Moren joins us this week! Rumors are circulating about an A18 MacBook Pro and iPhone 17 Air from Apple, Samsung just held its Galaxy Unpacked event this month and unveiled updates to some of its products, AI bots are scraping obituaries for profit, and a new browser war is emerging between two AI companies. Dan Moren talks about the rumored A18 MacBook Pro and iPhone 17 Air that Apple could announce this year as ways to appeal to broader consumer markets. Mikah Sargent shares the Galaxy Z Flip7, Galaxy Z Fold7, and the Galaxy Watch8 that Samsung unveiled at its recently held Galaxy Unpacked July 2025 event. Joe Supan of CNET joins the show to talk with Mikah about how AI is starting to scrape obituaries shared on social media networks like Facebook, and is being monetized for profit. And Mikah discusses an upcoming AI-powered browser war that looks to challenge Google Chrome, with companies like Perplexity launching Comet and OpenAI soon to launch its own web browser. Hosts: Mikah Sargent and Dan Moren Guest: Joe Supan Download or subscribe to Tech News Weekly at https://twit.tv/shows/tech-news-weekly. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: go.acronis.com/twit uscloud.com

This week, Lauren dives into the show's inbox to answer listeners' questions. With the help of WIRED's Kate Knibbs and Paresh Dave, we look into a range of queries — from how AI is shaping the film industry to brainstorming how the Jony Ive and Open AI's collaboration could look like. Articles mentioned in this episode:  This Viral AI Chatbot Will Lie and Say It's Human | WIRED  A Political Battle Is Brewing Over Data Centers | WIRED  Learn about your ad choices: dovetail.prx.org/ad-choices

Dan Moren joins us this week! Rumors are circulating about an A18 MacBook Pro and iPhone 17 Air from Apple, Samsung just held its Galaxy Unpacked event this month and unveiled updates to some of its products, AI bots are scraping obituaries for profit, and a new browser war is emerging between two AI companies. Dan Moren talks about the rumored A18 MacBook Pro and iPhone 17 Air that Apple could announce this year as ways to appeal to broader consumer markets. Mikah Sargent shares the Galaxy Z Flip7, Galaxy Z Fold7, and the Galaxy Watch8 that Samsung unveiled at its recently held Galaxy Unpacked July 2025 event. Joe Supan of CNET joins the show to talk with Mikah about how AI is starting to scrape obituaries shared on social media networks like Facebook, and is being monetized for profit. And Mikah discusses an upcoming AI-powered browser war that looks to challenge Google Chrome, with companies like Perplexity launching Comet and OpenAI soon to launch its own web browser. Hosts: Mikah Sargent and Dan Moren Guest: Joe Supan Download or subscribe to Tech News Weekly at https://twit.tv/shows/tech-news-weekly. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: go.acronis.com/twit uscloud.com

TO LEARN MORE:       www.CrossFitEdwardsville.com       www.Facebook.com/CrossFitEdwardsville      TikTok: @crossfitedwardsville      Instagram: @crossfitedwardsville        Twitter: @cfedwardsville        YouTube: CrossFit Edwardsville TO GET STARTED AT CFE:     Book a No-Sweat Conversation with a coach, using this scheduler:          https://crossfitedwardsville.com/intro/    You can also find the link to schedule on our website. While this show is educational & entertaining in nature, it does not replace or supplant professional medical guidance from your own physician. Before beginning any exercise or nutrition program, please first consult with your doctor. 

Is Silicon Valley building the future or just trying to rule it?From Elon Musk's new political party to retail investors buying fake OpenAI stock, the startup world is getting weirder, faster.In this episode, Chris Saad and Shira Lazar break down a massive week in tech, politics, and startup culture. They unpack Elon Musk's launch of the “America Party,” the legality of Robinhood and SoFi offering access to OpenAI and SpaceX shares, YouTube's crackdown on mass AI content, Sequoia Capital's culture war PR disaster, and the impressive metrics behind Figma's upcoming IPO.In this episode, you will:Learn why Elon Musk is launching a political party—and how it could shake up US politicsUnderstand how Robinhood and SoFi are fractionalizing access to top private companies like SpaceXDiscover the legal and ethical questions behind tokenized startup sharesExplore YouTube's new policy to demonetize “AI slop” and what it means for creatorsHear why a Sequoia partner's tweet has triggered backlash in tech VC circlesReflect on the growing disconnect between Silicon Valley values and social responsibilityWhether you're a startup founder, tech enthusiast, or just trying to make sense of where innovation is heading, this episode is your insider's guide to the stories shaping the future of business.The Pact Honor the Startup Podcast Pact! If you have listened to TSP and gotten value from it, please:Follow, rate, and review us in your listening appSubscribe to the TSP Mailing List to gain access to exclusive newsletter-only content and early access to information on upcoming episodes: https://thestartuppodcast.beehiiv.com/subscribe Secure your official TSP merchandise at https://shop.tsp.show/ Follow us here on YouTube for full-video episodes: https://www.youtube.com/channel/UCNjm1MTdjysRRV07fSf0yGg Give us a public shout-out on LinkedIn or anywhere you have a social media followingKey linksGet your question in for our next Q&A episode: https://forms.gle/NZzgNWVLiFmwvFA2A The Startup Podcast website: https://www.tsp.show/episodes/Learn more about Chris and YanivWork 1:1 with Chris: http://chrissaad.com/advisory/ Follow Chris on Linkedin: https://www.linkedin.com/in/chrissaad/ Follow Yaniv on Linkedin: https://www.linkedin.com/in/ybernstein/Producer: Justin McArthur https://www.linkedin.com/in/justin-mcarthurIntro Voice: Jeremiah Owyang https://web-strategist.com/

Dan Moren joins us this week! Rumors are circulating about an A18 MacBook Pro and iPhone 17 Air from Apple, Samsung just held its Galaxy Unpacked event this month and unveiled updates to some of its products, AI bots are scraping obituaries for profit, and a new browser war is emerging between two AI companies. Dan Moren talks about the rumored A18 MacBook Pro and iPhone 17 Air that Apple could announce this year as ways to appeal to broader consumer markets. Mikah Sargent shares the Galaxy Z Flip7, Galaxy Z Fold7, and the Galaxy Watch8 that Samsung unveiled at its recently held Galaxy Unpacked July 2025 event. Joe Supan of CNET joins the show to talk with Mikah about how AI is starting to scrape obituaries shared on social media networks like Facebook, and is being monetized for profit. And Mikah discusses an upcoming AI-powered browser war that looks to challenge Google Chrome, with companies like Perplexity launching Comet and OpenAI soon to launch its own web browser. Hosts: Mikah Sargent and Dan Moren Guest: Joe Supan Download or subscribe to Tech News Weekly at https://twit.tv/shows/tech-news-weekly. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: go.acronis.com/twit uscloud.com

Dr. Paul Hanona and Dr. Arturo Loaiza-Bonilla discuss how to safely and smartly integrate AI into the clinical workflow and tap its potential to improve patient-centered care, drug development, and access to clinical trials. TRANSCRIPT Dr. Paul Hanona: Hello, I'm Dr. Paul Hanona, your guest host of the ASCO Daily News Podcast today. I am a medical oncologist as well as a content creator @DoctorDiscover, and I'm delighted to be joined today by Dr. Arturo Loaiza-Bonilla, the chief of hematology and oncology at St. Luke's University Health Network. Dr. Bonilla is also the co-founder and chief medical officer at Massive Bio, an AI-driven platform that matches patients with clinical trials and novel therapies. Dr. Loaiza-Bonilla will share his unique perspective on the potential of artificial intelligence to advance precision oncology, especially through clinical trials and research, and other key advancements in AI that are transforming the oncology field. Our full disclosures are available in the transcript of the episode. Dr. Bonilla, it's great to be speaking with you today. Thanks for being here. Dr. Arturo Loaiza-Bonilla: Oh, thank you so much, Dr. Hanona. Paul, it's always great to have a conversation. Looking forward to a great one today. Dr. Paul Hanona: Absolutely. Let's just jump right into it. Let's talk about the way that we see AI being embedded in our clinical workflow as oncologists. What are some practical ways to use AI? Dr. Arturo Loaiza-Bonilla: To me, responsible AI integration in oncology is one of those that's focused on one principle to me, which is clinical purpose is first, instead of the algorithm or whatever technology we're going to be using. If we look at the best models in the world, they're really irrelevant unless we really solve a real day-to-day challenge, either when we're talking to patients in the clinic or in the infusion chair or making decision support. Currently, what I'm doing the most is focusing on solutions that are saving us time to be more productive and spend more time with our patients. So, for example, we're using ambient AI for appropriate documentation in real time with our patients. We're leveraging certain tools to assess for potential admission or readmission of patients who have certain conditions as well. And it's all about combining the listening of physicians like ourselves who are end users, those who create those algorithms, data scientists, and patient advocates, and even regulators, before they even write any single line of code. I felt that on my own, you know, entrepreneurial aspects, but I think it's an ethos that we should all follow. And I think that AI shouldn't be just bolted on later. We always have to look at workflows and try to look, for example, at clinical trial matching, which is something I'm very passionate about. We need to make sure that first, it's easier to access for patients, that oncologists like myself can go into the interface and be able to pull the data in real time when you really need it, and you don't get all this fatigue alerts. To me, that's the responsible way of doing so. Those are like the opportunities, right? So, the challenge is how we can make this happen in a meaningful way – we're just not reacting to like a black box suggestion or something that we have no idea why it came up to be. So, in terms of success – and I can tell you probably two stories of things that we know we're seeing successful – we all work closely with radiation oncologists, right? So, there are now these tools, for example, of automated contouring in radiation oncology, and some of these solutions were brought up in different meetings, including the last ASCO meeting. But overall, we know that transformer-based segmentation tools; transformer is just the specific architecture of the machine learning algorithm that has been able to dramatically reduce the time for colleagues to spend allotting targets for radiation oncology. So, comparing the target versus the normal tissue, which sometimes it takes many hours, now we can optimize things over 60%, sometimes even in minutes. So, this is not just responsible, but it's also an efficiency win, it's a precision win, and we're using it to adapt even mid-course in response to tumor shrinkage. Another success that I think is relevant is, for example, on the clinical trial matching side. We've been working on that and, you know, I don't want to preach to the choir here, but having the ability for us to structure data in real time using these tools, being able to extract information on biomarkers, and then show that multi-agentic AI is superior to what we call zero-shot or just throwing it into ChatGPT or any other algorithm, but using the same tools but just fine-tuned to the point that we can be very efficient and actually reliable to the level of almost like a research coordinator, is not just theory. Now, it can change lives because we can get patients enrolled in clinical trials and be activated in different places wherever the patient may be. I know it's like a long answer on that, but, you know, as we talk about responsible AI, that's important. And in terms of what keeps me up at night on this: data drift and biases, right? So, imaging protocols, all these things change, the lab switch between different vendors, or a patient has issues with new emerging data points. And health systems serve vastly different populations. So, if our models are trained in one context and deployed in another, then the output can be really inaccurate. So, the idea is to become a collaborative approach where we can use federated learning and patient-centricity so we can be much more efficient in developing those models that account for all the populations, and any retraining that is used based on data can be diverse enough that it represents all of us and we can be treated in a very good, appropriate way. So, if a clinician doesn't understand why a recommendation is made, as you probably know, you probably don't trust it, and we shouldn't expect them to. So, I think this is the next wave of the future. We need to make sure that we account for all those things. Dr. Paul Hanona: Absolutely. And even the part about the clinical trials, I want to dive a little bit more into in a few questions. I just kind of wanted to make a quick comment. Like you said, some of the prevalent things that I see are the ambient scribes. It seems like that's really taken off in the last year, and it seems like it's improving at a pretty dramatic speed as well. I wonder how quickly that'll get adopted by the majority of physicians or practitioners in general throughout the country. And you also mentioned things with AI tools regarding helping regulators move things quicker, even the radiation oncologist, helping them in their workflow with contouring and what else they might have to do. And again, the clinical trials thing will be quite interesting to get into. The first question I had subsequent to that is just more so when you have large datasets. And this pertains to two things: the paper that you published recently regarding different ways to use AI in the space of oncology referred to drug development, the way that we look at how we design drugs, specifically anticancer drugs, is pretty cumbersome. The steps that you have to take to design something, to make sure that one chemical will fit into the right chemical or the structure of the molecule, that takes a lot of time to tinker with. What are your thoughts on AI tools to help accelerate drug development? Dr. Arturo Loaiza-Bonilla: Yes, that's the Holy Grail and something that I feel we should dedicate as much time and effort as possible because it relies on multimodality. It cannot be solved by just looking at patient histories. It cannot be solved by just looking at the tissue alone. It's combining all these different datasets and being able to understand the microenvironment, the patient condition and prior treatments, and how dynamic changes that we do through interventions and also exposome – the things that happen outside of the patient's own control – can be leveraged to determine like what's the best next step in terms of drugs. So, the ones that we heard the news the most is, for example, the Nobel Prize-winning [for Chemistry awarded to Demis Hassabis and John Jumper for] AlphaFold, an AI system that predicts protein structures right? So, we solved this very interesting concept of protein folding where, in the past, it would take the history of the known universe, basically – what's called the Levinthal's paradox – to be able to just predict on amino acid structure alone or the sequence alone, the way that three-dimensionally the proteins will fold. So, with that problem being solved and the Nobel Prize being won, the next step is, “Okay, now we know how this protein is there and just by sequence, how can we really understand any new drug that can be used as a candidate and leverage all the data that has been done for many years of testing against a specific protein or a specific gene or knockouts and what not?” So, this is the future of oncology and where we're probably seeing a lot of investments on that. The key challenge here is mostly working on the side of not just looking at pathology, but leveraging this digital pathology with whole slide imaging and identifying the microenvironment of that specific tissue. There's a number of efforts currently being done. One isn't just H&E, like hematoxylin and eosin, slides alone, but with whole imaging, now we can use expression profiles, spatial transcriptomics, and gene whole exome sequencing in the same space and use this transformer technology in a multimodality approach that we know already the slide or the pathology, but can we use that to understand, like, if I knock out this gene, how is the microenvironment going to change to see if an immunotherapy may work better, right? If we can make a microenvironment more reactive towards a cytotoxic T cell profile, for example. So, that is the way where we're really seeing the field moving forward, using multimodality for drug discovery. So, the FDA now seems to be very eager to support those initiatives, so that's of course welcome. And now the key thing is the investment to do this in a meaningful way so we can see those candidates that we're seeing from different companies now being leveraged for rare disease, for things that are going to be almost impossible to collect enough data, and make it efficient by using these algorithms that sometimes, just with multiple masking – basically, what they do is they mask all the features and force the algorithm to find solutions based on the specific inputs or prompts we're doing. So, I'm very excited about that, and I think we're going to be seeing that in the future. Dr. Paul Hanona: So, essentially, in a nutshell, we're saying we have the cancer, which is maybe a dandelion in a field of grass, and we want to see the grass that's surrounding the dandelion, which is the pathology slides. The problem is, to the human eye, it's almost impossible to look at every single piece of grass that's surrounding the dandelion. And so, with tools like AI, we can greatly accelerate our study of the microenvironment or the grass that's surrounding the dandelion and better tailor therapy, come up with therapy. Otherwise, like you said, to truly generate a drug, this would take years and years. We just don't have the throughput to get to answers like that unless we have something like AI to help us. Dr. Arturo Loaiza-Bonilla: Correct. Dr. Paul Hanona: And then, clinical trials. Now, this is an interesting conversation because if you ever look up our national guidelines as oncologists, there's always a mention of, if treatment fails, consider clinical trials. Or in the really aggressive cancers, sometimes you might just start out with clinical trials. You don't even give the standard first-line therapy because of how ineffective it is. There are a few issues with clinical trials that people might not be aware of, but the fact that the majority of patients who should be on clinical trials are never given the chance to be on clinical trials, whether that's because of proximity, right, they might live somewhere that's far from the institution, or for whatever reason, they don't qualify for the clinical trial, they don't meet the strict inclusion criteria.  But a reason you mentioned early on is that it's simply impossible for someone to be aware of every single clinical trial that's out there. And then even if you are aware of those clinical trials, to actually find the sites and put in the time could take hours. And so, how is AI going to revolutionize that? Because in my mind, it's not that we're inventing a new tool. Clinical trials have always been available. We just can't access them. So, if we have a tool that helps with access, wouldn't that be huge? Dr. Arturo Loaiza-Bonilla: Correct. And that has been one of my passions. And for those who know me and follow me and we've spoke about it in different settings, that's something that I think we can solve. This other paradox, which is the clinical trial enrollment paradox, right? We have tens of thousands of clinical trials available with millions of patients eager to learn about trials, but we don't enroll enough and many trials close to accrual because of lack of enrollment. It is completely paradoxical and it's because of that misalignment because patients don't know where to go for trials and sites don't know what patients they can help because they haven't reached their doors yet. So, the solution has to be patient-centric, right? We have to put the patient at the center of the equation. And that was precisely what we had been discussing during the ASCO meeting. There was an ASCO Education Session where we talked about digital prescreening hubs, where we, in a patient-centric manner, the same way we look for Uber, Instacart, any solution that you may think of that you want something that can be leveraged in real time, we can use these real-world data streams from the patient directly, from hospitals, from pathology labs, from genomics companies, to continuously screen patients who can match to the inclusion/exclusion criteria of unique trials. So, when the patient walks into the clinic, the system already knows if there's a trial and alerts the site proactively. The patient can actually also do decentralization. So, there's a number of decentralized clinical trial solutions that are using what I call the “click and mortar” approach, which is basically the patient is checking digitally and then goes to the site to activate. We can also have the click and mortar in the bidirectional way where the patient is engaged in person and then you give the solution like the ones that are being offered on things that we're doing at Massive Bio and beyond, which is having the patient to access all that information and then they make decisions and enroll when the time is right.  As I mentioned earlier, there is this concept drift where clinical trials open and close, the patient line of therapy changes, new approvals come in and out, and sites may not be available at a given time but may be later. So, having that real-time alerts using tools that are able already to extract data from summarization that we already have in different settings and doing this natural language ingestion, we can not only solve this issue with manual chart review, which is extremely cumbersome and takes forever and takes to a lot of one-time assessments with very high screen failures, to a real-time dynamic approach where the patient, as they get closer to that eligibility criteria, they get engaged. And those tools can be built to activate trials, audit trials, and make them better and accessible to patients. And something that we know is, for example, 91%-plus of Americans live close to either a pharmacy or an imaging center. So, imagine that we can potentially activate certain of those trials in those locations. So, there's a number of pharmacies, special pharmacies, Walgreens, and sometimes CVS trying to do some of those efforts. So, I think the sky's the limit in terms of us working together. And we've been talking with corporate groups, they're all interested in those efforts as well, to getting patients digitally enabled and then activate the same way we activate the NCTN network of the corporate groups, that are almost just-in-time. You can activate a trial the patient is eligible for and we get all these breakthroughs from the NIH and NCI, just activate it in my site within a week or so, as long as we have the understanding of the protocol. So, using clinical trial matching in a digitally enabled way and then activate in that same fashion, but not only for NCTN studies, but all the studies that we have available will be the key of the future through those prescreening hubs. So, I think now we're at this very important time where collaboration is the important part and having this silo-breaking approach with interoperability where we can leverage data from any data source and from any electronic medical records and whatnot is going to be essential for us to move forward because now we have the tools to do so with our phones, with our interests, and with the multiple clinical trials that are coming into the pipelines. Dr. Paul Hanona: I just want to point out that the way you described the process involves several variables that practitioners often don't think about. We don't realize the 15 steps that are happening in the background. But just as a clarifier, how much time is it taking now to get one patient enrolled on a clinical trial? Is it on the order of maybe 5 to 10 hours for one patient by the time the manual chart review happens, by the time the matching happens, the calls go out, the sign-up, all this? And how much time do you think a tool that could match those trials quicker and get you enrolled quicker could save? Would it be maybe an hour instead of 15 hours? What's your thought process on that? Dr. Arturo Loaiza-Bonilla: Yeah, exactly. So one is the matching, the other one is the enrollment, which, as you mentioned, is very important. So, it can take, from, as you said, probably between 4 days to sometimes 30 days. Sometimes that's how long it takes for all the things to be parsed out in terms of logistics and things that could be done now agentically. So, we can use agents to solve those different steps that may take multiple individuals. We can just do it as a supply chain approach where all those different steps can be done by a single agent in a simultaneous fashion and then we can get things much faster. With an AI-based solution using these frontier models and multi-agentic AI – and we presented some of this data in ASCO as well – you can do 5,000 patients in an hour, right? So, just enrolling is going to be between an hour and maximum enrollment, it could be 7 days for those 5,000 patients if it was done at scale in a multi-level approach where we have all the trials available. Dr. Paul Hanona: No, definitely a very exciting aspect of our future as oncologists. It's one thing to have really neat, novel mechanisms of treatment, but what good is it if we can't actually get it to people who need it? I'm very much looking for the future of that.  One of the last questions I want to ask you is another prevalent way that people use AI is just simply looking up questions, right? So, traditionally, the workflow for oncologists is maybe going on national guidelines and looking up the stage of the cancer and seeing what treatments are available and then referencing the papers and looking at who was included, who wasn't included, the side effects to be aware of, and sort of coming up with a decision as to how to treat a cancer patient. But now, just in the last few years, we've had several tools become available that make getting questions easier, make getting answers easier, whether that's something like OpenAI's tools or Perplexity or Doximity or OpenEvidence or even ASCO has a Guidelines Assistant as well that is drawing from their own guidelines as to how to treat different cancers. Do you see these replacing traditional sources? Do you see them saving us a lot more time so that we can be more productive in clinic? What do you think is the role that they're going to play with patient care? Dr. Arturo Loaiza-Bonilla: Such a relevant question, particularly at this time, because these AI-enabled query tools, they're coming left and right and becoming increasingly common in our daily workflows and things that we're doing. So, traditionally, when we go and we look for national guidelines, we try to understand the context ourselves and then we make treatment decisions accordingly. But that is a lot of a process that now AI is helping us to solve. So, at face value, it seems like an efficiency win, but in many cases, I personally evaluate platforms as the chief of hem/onc at St. Luke's and also having led the digital engagement things through Massive Bio and trying to put things together, I can tell you this: not all tools are created equal. In cancer care, each data point can mean the difference between cure and progression, so we cannot really take a lot of shortcuts in this case or have unverified output. So, the tools are helpful, but it has to be grounded in truth, in trusted data sources, and they need to be continuously updated with, like, ASCO and NCCN and others. So, the reason why the ASCO Guidelines Assistant, for instance, works is because it builds on all these recommendations, is assessed by end users like ourselves. So, that kind of verification is critical, right? We're entering a phase where even the source material may be AI-generated. So, the role of human expert validation is really actually more important, not less important. You know, generalist LLMs, even when fine-tuned, they may not be enough. You can pull a few API calls from PubMed, etc., but what we need now is specialized, context-aware, agentic tools that can interpret multimodal and real-time clinical inputs. So, something that we are continuing to check on and very relevant to have entities and bodies like ASCO looking into this so they can help us to be really efficient and really help our patients. Dr. Paul Hanona: Dr. Bonilla, what do you want to leave the listener with in terms of the future direction of AI, things that we should be cautious about, and things that we should be optimistic about? Dr. Arturo Loaiza-Bonilla: Looking 5 years ahead, I think there's enormous promise. As you know, I'm an AI enthusiast, but always, there's a few priorities that I think – 3 of them, I think – we need to tackle head-on. First is algorithmic equity. So, most AI tools today are trained on data from academic medical centers but not necessarily from community practices or underrepresented populations, particularly when you're looking at radiology, pathology, and what not. So, those blind spots, they need to be filled, and we can eliminate a lot of disparities in cancer care. So, those frameworks to incentivize while keeping the data sharing using federated models and things that we can optimize is key. The second one is the governance on the lifecycle. So, you know, AI is not really static. So, unlike a drug that is approved and it just, you know, works always, AI changes. So, we need to make sure that we have tools that are able to retrain and recall when things degrade or models drift. So, we need to use up-to-date AI for clinical practice, so we are going to be in constant revalidation and make it really easy to do. And lastly, the human-AI interface. You know, clinicians don't need more noise or we don't need more black boxes. We need decision support that is clear, that we can interpret, and that is actionable. “Why are you using this? Why did we choose this drug? Why this dose? Why now?” So, all these things are going to help us and that allows us to trace evidence with a single click. So, I always call it back to the Moravec's paradox where we say, you know, evolution gave us so much energy to discern in the sensory-neural and dexterity. That's what we're going to be taking care of patients. We can use AI to really be a force to help us to be better clinicians and not to really replace us. So, if we get this right and we decide for transparency with trust, inclusion, etc., it will never replace any of our work, which is so important, as much as we want, we can actually take care of patients and be personalized, timely, and equitable. So, all those things are what get me excited every single day about these conversations on AI. Dr. Paul Hanona: All great thoughts, Dr. Bonilla. I'm very excited to see how this field evolves. I'm excited to see how oncologists really come to this field. I think with technology, there's always a bit of a lag in adopting it, but I think if we jump on board and grow with it, we can do amazing things for the field of oncology in general. Thank you for the advancements that you've made in your own career in the field of AI and oncology and just ultimately with the hopeful outcomes of improving patient care, especially cancer patients. Dr. Arturo Loaiza-Bonilla: Thank you so much, Dr. Hanona. Dr. Paul Hanona: Thanks to our listeners for your time today. If you value the insights that you hear on ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. More on today's speakers:    Dr. Arturo Loaiza-Bonilla @DrBonillaOnc Dr. Paul Hanona @DoctorDiscover on YouTube Follow ASCO on social media:      @ASCO on Twitter      ASCO on Facebook      ASCO on LinkedIn    ASCO on BlueSky Disclosures: Paul Hanona: No relationships to disclose. Dr. Arturo-Loaiza-Bonilla: Leadership: Massive Bio Stock & Other Ownership Interests: Massive Bio Consulting or Advisory Role: Massive Bio, Bayer, PSI, BrightInsight, CardinalHealth, Pfizer, AstraZeneca, Medscape Speakers' Bureau: Guardant Health, Ipsen, AstraZeneca/Daiichi Sankyo, Natera

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Send us a textJoin hosts Alex Sarlin and Ben Kornell with guest Jacob Kantor as they explore a transformative Week-in-Edtech, from Google's AI-powered classroom revolution to major political shifts affecting schools nationwide.Episode Highlights:[00:03:17] Google launches 50 AI tools for educators through Classroom and Gemini[00:05:47] Startup funding threatened as Google expands free AI features[00:13:41] Google solidifies K-12 dominance, pushing out AI competitors[00:24:51] OpenAI and Microsoft fund new AI training hub for 400,000 teachers[00:33:22] Survey finds 60% of teachers using AI, saving nearly 6 hours per week [00:36:22] Federal government freezes $6B in school funding, including EL programs[00:38:17] ICE raids linked to 30% rise in school absences among Latino students[00:43:32] Families turning to private edtech as school trust declines[00:46:49] ISTE highlights include Amplify, Brisk, Quizziz rebrand, Meta's school mode[00:50:34] Edtech Insiders WhatsApp group emerges as top source for breaking newsPlus, special guests:[00:51:36] Matt Dalio, Founder of Endless Studios on teaching real-world skills through student-designed video games[00:53:56] Anne Trumbore, author of The Teacher in the Machine, on AI, learning platforms, and the future of teaching

Serious question, why call something Rebirth, if there is no rebirthing, where was the rebirthing? Yes I have a full review of Jurassic World Rebirth in todays drop. Plus more fallout from the Microsoft and Xbox layoffs, and who is to blame? Helldivers 2 is dropping on Xbox next month, and Nintendo ponders the future of game development. ScarJo is now the highest grossing lead actor ever, John M Chu is going to be racing into theaters as the director of Hot Wheels. Meanwhile James Gunn and Zack Snyder portal into Rick and Morty in the least suspecting way.

Dan Moren joins us this week! Rumors are circulating about an A18 MacBook Pro and iPhone 17 Air from Apple, Samsung just held its Galaxy Unpacked event this month and unveiled updates to some of its products, AI bots are scraping obituaries for profit, and a new browser war is emerging between two AI companies. Dan Moren talks about the rumored A18 MacBook Pro and iPhone 17 Air that Apple could announce this year as ways to appeal to broader consumer markets. Mikah Sargent shares the Galaxy Z Flip7, Galaxy Z Fold7, and the Galaxy Watch8 that Samsung unveiled at its recently held Galaxy Unpacked July 2025 event. Joe Supan of CNET joins the show to talk with Mikah about how AI is starting to scrape obituaries shared on social media networks like Facebook, and is being monetized for profit. And Mikah discusses an upcoming AI-powered browser war that looks to challenge Google Chrome, with companies like Perplexity launching Comet and OpenAI soon to launch its own web browser. Hosts: Mikah Sargent and Dan Moren Guest: Joe Supan Download or subscribe to Tech News Weekly at https://twit.tv/shows/tech-news-weekly. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: go.acronis.com/twit uscloud.com

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Stock market update for July 10, 2025.

Elon Musk spent almost an hour talking about Grok without mentioning its Nazi problem, Samsung plans to launch its trifold smartphone by the end of the year, and OpenAI's own web browser could arrive within weeks. It's Thursday, July 10th and here's a quick look at tech in the news this morning from Engadget. Learn more about your ad choices. Visit podcastchoices.com/adchoices

i'm wall-e, welcoming you to today's tech briefing for thursday, july 10th. get updates on: microsoft's ai-driven efficiency: over $500 million in annual savings reported, with substantial workforce reductions and a strategic pivot towards ai investments following $26 billion in quarterly profit. openai's new browser: challenge to google chrome with an ai-driven browser that aims to revolutionize web interactions and retain users within the chatgpt environment. california's ai regulation progress: state senator scott wiener's amendments to sb 53 could lead to enhanced ai safety protocols, positioning california as a leader in ai regulation. revolut's soaring fintech valuation: seeking a $65 billion valuation amid a 72% revenue jump and a customer base of over 50 million. youtube's policy tightening: adjustments to monetization guidelines to combat "mass-produced" ai-generated content and maintain content quality. that's all for today. we'll see you back here tomorrow!

Episode 622: Neal and Toby talk about the Trump Administration banning Chinese buyers from acquiring US farmlands. Then, Robinhood is offering faux equities as tokens and OpenAI is not happy about it. Also, middle managers are being axed which means top managers are adopting more workers. Plus, a polymarket controversy over whether President Zelenskyy wore a suit or not. Finally, a wrap up of more headlines.  Meet your local home loan expert at ⁠⁠https://mortgagematchup.com/?utm_source=morning_brew&utm_medium=podcast  Join us for trivia night! https://mbd-trivianight-july15.splashthat.com/ Subscribe to Morning Brew Daily for more of the news you need to start your day. Share the show with a friend, and leave us a review on your favorite podcast app. Listen to Morning Brew Daily Here:⁠ ⁠⁠https://www.swap.fm/l/mbd-note⁠⁠⁠  Watch Morning Brew Daily Here:⁠ ⁠⁠https://www.youtube.com/@MorningBrewDailyShow⁠

The 2025 generative AI image market is a trade-off between aesthetic quality, instruction-following, and user control. This episode analyzes the key platforms, comparing Midjourney's artistic output against the superior text generation and prompt adherence of GPT-4o and Imagen 4, the commercial safety of Adobe Firefly, and the total customization of Stable Diffusion. Links Notes and resources at ocdevel.com/mlg/mla-25 Try a walking desk - stay healthy & sharp while you learn & code Build the future of multi-agent software with AGNTCY. The State of the Market The market is split by three core philosophies: The "Artist" (Midjourney): Prioritizes aesthetic excellence and cinematic output, sacrificing precise user control and instruction following. The "Collaborator" (GPT-4o, Imagen 4): Extensions of LLMs that excel at conversational co-creation, complex instruction following, and integration into productivity workflows. The "Sovereign Toolkit" (Stable Diffusion): An open-source engine offering users unparalleled control, customization, and privacy in exchange for technical engagement. Table 1: 2025 Generative AI Image Tool At-a-Glance Comparison Tool Parent Company Access Method(s) Pricing Core Strength Best For Midjourney v7 Midjourney, Inc. Web App, Discord Subscription Artistic Aesthetics & Photorealism Fine Art, Concept Design, Stylized Visuals GPT-4o OpenAI ChatGPT, API Freemium/Sub Conversational Control & Instruction Following Marketing Materials, UI/UX Mockups, Logos Google Imagen 4 Google Gemini, Workspace, Vertex AI Freemium/Sub Ecosystem Integration & Speed Business Presentations, Educational Content Stable Diffusion 3 Stability AI Local Install, Web UIs, API Open Source Ultimate Customization & Control Developers, Power Users, Bespoke Workflows Adobe Firefly Adobe Creative Cloud Apps, Web App Subscription Commercial Safety & Workflow Integration Professional Designers, Agencies, Enterprise Core Platforms Midjourney v7: Premium choice for artistic quality. Features: Web UI with Draft Mode, user personalization, emerging video/3D. Weaknesses: Poor text generation, poor prompt adherence, public images on cheap plans, no API/bans automation. OpenAI GPT-4o: An intelligent co-creator for controlled generation. Features: Conversational refinement, superior text rendering, understands uploaded image context. Weaknesses: Slower than competitors, generates one image at a time, strict content filters. Google Imagen 4: Pragmatic tool focused on speed and ecosystem integration. Features: High-quality photorealism, fast generation, strong text rendering, multilingual. Weaknesses: Less artistic flair; value is dependent on Google ecosystem investment. Stable Diffusion 3: Open-source engine for maximum user control. Features: MMDiT architecture improves prompt/text handling, scalable models, vast ecosystem (LoRAs/ControlNet). Weaknesses: Steep learning curve, quality is user-dependent. Adobe Firefly: Focused on commercial safety and professional workflow integration. Features: Trained on Adobe Stock for legal indemnity, Generative Fill/Expand tools. Weaknesses: Creative range limited by training data, requires Adobe subscription/credits. Tools and Concepts In-painting: Modifying a masked area inside an image. Out-painting: Extending an image beyond its original borders. LoRA (Low-Rank Adaptation): A small file that applies a fine-tuned style, character, or concept to a base model. ControlNet: Uses a reference image (e.g., pose, sketch) to enforce the composition, structure, or pose of the output. A1111 vs. ComfyUI: Two main UIs for Stable Diffusion. A1111 is a beginner-friendly tabbed interface; ComfyUI is a node-based interface for complex, efficient, and automated workflows. Workflows "Best of Both Worlds": Generate aesthetic base images in Midjourney, then composite, edit, and add text with precision in Photoshop/Firefly. Single-Ecosystem: Work entirely within Adobe Creative Cloud or Google Workspace for seamless integration, commercial safety (Adobe), and convenience (Google). "Build Your Own Factory": Use ComfyUI to build automated, multi-step pipelines for consistent character generation, advanced upscaling, and video. Decision Framework Choose by Goal: Fine Art/Concept Art: Midjourney. Logos/Ads with Text: GPT-4o, Google Imagen 4, or specialist Ideogram. Consistent Character in Specific Pose: Stable Diffusion with a Character LoRA and ControlNet (OpenPose). Editing/Expanding an Existing Photo: Adobe Photoshop with Firefly. Exclusion Rules: If you need legible text, exclude Midjourney. If you need absolute privacy or zero cost (post-hardware), Stable Diffusion is the only option. If you need guaranteed commercial legal safety, use Adobe Firefly. If you need an API for a product, use OpenAI or Google; automating Midjourney is a bannable offense.

Think you know ChatGPT's custom GPTs?

When the first video diffusion models started emerging, they were little more than just “moving pictures” - still frames extended a few seconds in either direction in time. There was a ton of excitement about OpenAI's Sora on release through 2024, but so far only Sora-lite has been widely released. Meanwhile, other good videogen models like Genmo Mochi, Pika, MiniMax T2V, Tencent Hunyuan Video, and Kuaishou's Kling have emerged, but the reigning king this year seems to be Google's Veo 3, which for the first time has added native audio generation into their model capabilities, eliminating the need for a whole class of lipsynching tooling and SFX editing. The rise of Veo 3 unlocks a whole new category of AI Video creators that many of our audience may not have been exposed to, but is undeniably effective and important particularly in the “kids” and “brainrot” segments of the global consumer internet platforms like Tiktok, YouTube and Instagram. By far the best documentarians of these trends for laypeople are Olivia and Justine Moore, both partners at a16z, who not only collate the best examples from all over the web, but dabble in video creation themselves to put theory into practice. We've been thinking of dabbling in AI brainrot on a secondary channel for Latent Space, so we wanted to get the braindump from the Moore twins on how to make a Latent Space Brainrot channel. Jump on in! Chapters 00:00:00 Introductions & Guest Welcome 00:00:49 The Rise of Generative Media 00:02:24 AI Video Trends: Italian Brain Rot & Viral Characters 00:05:00 Following Trends & Creating AI Content 00:07:17 Hands-On with AI Video Creation 00:18:36 Monetization & Business of AI Content 00:23:34 Platforms, Models, and the Creator Stack 00:37:22 Native Content vs. Clipping & Going Viral 00:41:52 Prompt Theory & Meta-Trends in AI Creativity 00:47:42 Professional, Commercial, and Platform-Specific AI Video 00:48:57 Wrap-Up & Final Thoughts

C'est la startup la mieux valorisée au mode ! 300 mds de dollars, voilà ce que vaut la maison-mère de ChatGPT en cet été 2025

Superintelligence is coming faster than anyone predicted. In this episode, you'll learn how to upgrade your biology, brain, and consciousness before AI and transhumanism reshape the future of health. Host Dave Asprey sits down with Soren Gordhamer, founder of Wisdom 2.0, to explore what superintelligence in 2027 means for your mind, body, and soul. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Soren has spent decades at the intersection of mindfulness, technology, and human development. He advises leaders at OpenAI, Google, and top wellness companies, and he leads global conversations around AI and consciousness. His work bridges ancient wisdom with biohacking, modern neuroscience, and the urgent need to stay human in a machine-dominated world. This episode gives you a tactical roadmap to build resilience before the world tilts. You'll gain practical tools for brain optimization, functional medicine, and biohacking strategies that sharpen cognitive health, reinforce emotional stability, and unlock peak human performance in a digital-first reality. From supplements and nootropics to neuroplasticity techniques, Dave and Soren show you how to protect your biology as AI accelerates beyond human speed. They break down how AI and human health intersect, explain why you need emotional strength to face the future, and offer guidance for raising kids in a world ruled by code. If you're preparing for 2027 superintelligence, navigating AI-driven parenting, or staying ahead of transhumanist health tech, this episode equips you for the coming wave. You'll Learn: • How AI is reshaping human connection, presence, and identity • Why emotional resilience and conscious awareness matter more than ever in an AI-driven world • How to raise connected, grounded children in a hyper-digital environment • What human flourishing looks like when technology outpaces biology • Why investing in presence, purpose, and inner development may be the ultimate upgrade • How leaders in wellness and tech are rethinking personal growth, governance, and ethics in 2027 • What it means to stay truly human—and fully alive—during the rise of superintelligence Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes drop every Tuesday and Thursday, where Dave asks the questions no one else dares and gives you real tools to become more resilient, aware, and high performing. SPONSORS: - LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE. - ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Soren's New Book - The Essential: https://a.co/d/dALv7OS • Soren's Website: www.sorengordhamer.net • Soren's Instagram: https://www.instagram.com/wisdom2events/ • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Labs: https://upgradelabs.com • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On this TCAF Tuesday, ⁠⁠⁠⁠Michael Batnick⁠⁠⁠⁠ is here with a special edition of What Are Your Thoughts with special guests Cullen Roche, Eric Balchunas and Alex Kantrowitz. They discuss: who can replace the dollar, will the deficit crush us, the most successful ETF ever, if Apple should buy Perplexity, Meta vs OpenAI, and more. This episode is sponsored by Grayscale. Curious about investing in crypto and not sure where to start? Visit: https://www.grayscale.com/ to learn more.   Sign up for ⁠⁠⁠⁠The Compound Newsletter⁠⁠⁠⁠ and never miss out! Instagram: ⁠⁠⁠⁠https://instagram.com/thecompoundnews⁠⁠⁠⁠ Twitter: ⁠⁠⁠⁠https://twitter.com/thecompoundnews⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/company/the-compound-media/⁠⁠⁠⁠ TikTok: ⁠⁠⁠⁠https://www.tiktok.com/@thecompoundnews⁠⁠⁠⁠ Investing involves the risk of loss. This podcast is for informational purposes only and should not be or regarded as personalized investment advice or relied upon for investment decisions. Michael Batnick and Josh Brown are employees of Ritholtz Wealth Management and may maintain positions in the securities discussed in this video. All opinions expressed by them are solely their own opinion and do not reflect the opinion of Ritholtz Wealth Management. The Compound Media, Incorporated, an affiliate of ⁠⁠⁠⁠Ritholtz Wealth Management⁠⁠⁠⁠, receives payment from various entities for advertisements in affiliated podcasts, blogs and emails. Inclusion of such advertisements does not constitute or imply endorsement, sponsorship or recommendation thereof, or any affiliation therewith, by the Content Creator or by Ritholtz Wealth Management or any of its employees. For additional advertisement disclaimers see here ⁠⁠⁠⁠https://ritholtzwealth.com/advertising-disclaimers⁠⁠⁠⁠. Investments in securities involve the risk of loss. Any mention of a particular security and related performance data is not a recommendation to buy or sell that security. The information provided on this website (including any information that may be accessed through this website) is not directed at any investor or category of investors and is provided solely as general information. Obviously nothing on this channel should be considered as personalized financial advice or a solicitation to buy or sell any securities. See our disclosures here: ⁠⁠⁠⁠https://ritholtzwealth.com/podcast-youtube-disclosures/ Learn more about your ad choices. Visit megaphone.fm/adchoices

How much further behind can Apple get in AI now that Zuck is poaching from them as well? OpenAI has been forced to batten down the hatches, quite literally. A fully licensed AI video model. And back to Apple. They heard your complaints. They're pumping the brakes on Liquid Glass a bit.Sponsors:AGNTCY.ORGLinks:Apple Loses Top AI Models Executive to Meta's Hiring Spree (Bloomberg)OpenAI's Stock Compensation Reflect Steep Costs of Talent Wars (The Information)OpenAI clamps down on security after foreign spying threats (Financial Times)Bluesky can really keep up with the news now that it has activity notifications (The Verge)This New AI Tool Wants to Work With Filmmakers—Not Replace Them (Time)iOS 26 beta 3 dials back Liquid Glass (TechCrunch)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

A look inside CoreWeave's neocloud business model, and how the company went from an ETH miner to a $75 billion business. FILL OUT THE SURVEY BY CLICKING HEREWelcome back to The Mining Pod! Today, Colin and Will break down CoreWeave's meteoric rise to a $75+ billion valuation and why Bitcoin miners like Core Scientific, Galaxy Digital, and Applied Digital are all racing to partner with AI cloud providers. We explore CoreWeave's neocloud business model, GPU economics vs bitcoin mining profitability, and what this means for the future of the mining industry.Subscribe to our newsletter! **Notes:**• CoreWeave valued at $75B+ (12x revenue multiple)• 72% of Q1 revenue came from Microsoft/OpenAI• CoreWeave manages 250,000+ GPUs globally• $15B+ in contracted revenue securedTimestamps:00:00 Start04:05 Coreweave overview07:40 Neocloud10:28 Other Neocloud providers12:49 Oracle, OpenAI & Stargate16:20 Crusoe17:58 Hyperscaler street cred21:08 Energy pipeline26:53 Revenue32:51 Capex vs revenue38:03 GPU lifespan41:58 Bull vs Bear49:00 Partner concentration