Podcasts about cognitive decline

Life is longer for “those who think young”; Watching too much TV may shrink your brain (literally!); Diet and supplements may help lupus; When a high-fiber diet before surgery may be inadvisable; Your mouth may be the gateway to your overall health and longevity.

This episode features an interview with Dr. Jennifer Deal regarding the complex link between hearing loss and cognitive decline in older adults. Dr. Deal explains several hypotheses for how hearing impairment may cause cognitive decline, including increased cognitive load, structural brain changes, and social isolation. She highlights findings from the ACHIEVE trial, which suggest that while hearing interventions might not help everyone, they appear to slow cognitive decline in high-risk populations. Furthermore, the episode addresses the methodological challenges of testing patients with sensory deficits and advocates for universal accommodations in clinical settings. Ultimately, the episode underscores the importance of treating hearing loss to improve quality of life and potentially preserve long-term brain health. Show notes are available at www.NavNeuro.com/196 _________________ If you'd like to support the show, here are a few easy ways: 1) Get CE credits for listening to select episodes: www.NavNeuro.com/INS (for step-by-step guidance, go to: www.NavNeuro.com/CEguide) 2) Subscribe (free) and leave an Apple Podcasts rating/review: www.NavNeuro.com/itunes 3) Check out our book Becoming a Neuropsychologist, and leave it an Amazon rating   Thanks for listening, and join us next time as we continue to navigate the brain and behavior! [Note: This podcast and all linked content is intended for general educational purposes only and does not constitute the practice of psychology or any other professional healthcare advice and services. No professional relationship is formed between hosts and listeners. All content is to be used at listeners' own risk. Users should always seek appropriate medical and psychological care from their licensed healthcare provider.]

This week's supplement spotlight—spermidine; American Heart Association does a 180° on coffee; How accurate are health tracker wearables for sleep, blood pressure, heart rate? A skin disorder practically no one has heard of is often confused for skin cancer; Vitamin D—what forms and what dosages are optimal? Popular sugar substitutes may be worse for the brain than natural sugar.

Explore how saturated fat, oxidized cholesterol, and caffeine affect brain health, and why a whole food, low-fat diet helps prevent dementia and support cognition. #BrainHealth #DementiaPrevention #HealthyFats #HealthTalks

Artificial Sweeteners & Cognitive Decline, Myosteatosis on Coronary CT, Merck's Oral PCSK9 Inhibitor, Cyclospora Outbreak, Gut-Brain Synchronization, and the Banana Smoothie Mistake Explained Artificial Sweeteners Linked To 62% Faster Cognitive Decline In Landmark Brazilian Study A study tracking more than 12,700 adults (average age 52) over eight years found that people consuming the most artificial and low-calorie sweeteners, roughly 191 mg a day, about what's in a single can of diet soda, showed cognitive decline 62% faster than the lowest-intake group, equivalent to 1.6 extra years of brain aging, with memory hit hardest. Six of the seven sweeteners tested, including aspartame, saccharin, and acesulfame K, were linked to faster decline; tagatose was the lone exception. Researchers point to gut-microbiome disruption, altered glucose and insulin signaling, and possible direct neuronal effects as plausible mechanisms. Host Dave Asprey breaks down why a dose this small was enough to move the curve, why tagatose deserves more scrutiny before being called "safe," and where diet products' short-term weight-loss marketing conveniently ignores the long-term cost to your brain. Source: https://www.inc.com/kevin-haynes/study-links-cognitive-decline-to-surprisingly-small-daily-amount-of-artificial-sweeteners/91376522 ~~ AI Analysis Of 1,722 Heart Scans Finds Muscle Quality Predicts Heart Attacks Independent Of Calcium Score Using data from the SCOT-HEART trial, a University of Edinburgh team ran an AI model against ten years of coronary CT angiogram scans, measuring skeletal muscle attenuation, a marker of myosteatosis, or fat infiltration into muscle tissue. Every 10-point increase in muscle density corresponded to a 31% lower heart attack risk and 39% lower all-cause mortality over the following decade, and critically, this held independent of coronary calcium score, the current gold-standard risk marker. The same low-density-muscle patients also showed higher lung attenuation, lower liver attenuation, and more torso fat volume, a pattern consistent with systemic insulin resistance rather than a muscle-specific issue. Host Dave Asprey unpacks why calcium score isn't capturing the full risk picture, why myosteatosis is really a readout of whole-body insulin sensitivity, and what he'd add to a routine workup on top of a calcium score. Source: https://www.theguardian.com/science/2026/jun/30/strong-chest-back-less-likely-heart-attack-analysis ~~ FDA Approves First Oral PCSK9 Inhibitor, Cutting LDL By Up To 60% Without Injections Merck's enlicitide (brand name Lipfendra) is now FDA-approved as the first once-daily oral PCSK9 inhibitor, lowering LDL cholesterol by up to 60% in a phase 3 trial of 2,912 patients, routinely bringing levels down to 50-60 mg/dL. It works by blocking PCSK9, a liver protein that tags LDL receptors for destruction, the same target as injectable drugs like Repatha and Praluent, which have shown roughly 20% reductions in heart attacks and strokes in high-risk patients. Lipfendra is priced at $315 for a 30-day supply, with no excess side effects reported versus placebo over six months, though long-term outcome data is still pending. Host Dave Asprey explains why crushing total LDL without checking ApoB, LDL particle number, or oxidized LDL is optimizing the wrong variable, and what he'd want on his labs before considering a drug like this. Sources: https://www.nytimes.com/2026/07/16/science/the-fda-approves-a-new-pill-to-slash-cholesterol-levels.html https://www.cnbc.com/2026/07/16/mercks-cholesterol-pill-gets-us-fda-approval.html ~~ Cyclospora Outbreak Tied To Taylor Farms Lettuce Spreads To 34 States, Prompts Nationwide Recall Federal investigators have linked a multistate cyclosporiasis outbreak to shredded iceberg lettuce from Taylor Farms de Mexico, with Michigan alone logging over 5,000 cases and 100+ hospitalizations, much of it traced to lettuce used at Taco Bell. Taylor Farms has recalled all iceberg lettuce sourced from central Mexico, and Walmart has pulled Marketside Iceberg Salad and Marketside Shredded Lettuce with specific date codes across 27 states. Cyclospora spreads through fecal contamination and causes weeks of watery, explosive diarrhea if untreated; washing doesn't reliably eliminate it, since the parasite requires heat above 158°F to inactivate. Host Dave Asprey explains why pre-washed, pre-cut bagged greens remain a recurring contamination risk no matter what the label claims, and connects the outbreak's gut damage to lingering gut-brain consequences long after symptoms resolve. Sources: https://www.usatoday.com/story/news/health/2026/07/18/taylor-farms-shredded-lettuce-sample-cyclospora/90969103007/ https://www.fda.gov/food/outbreaks-foodborne-illness/investigation-5-state-outbreak-cyclospora-illnesses-iceberg-lettuce-july-2026 ~~ New Research Links Excessive Gut-Brain Synchronization To Anxiety And Depression Emerging research on the enteric nervous system, which contains over 100 million neurons and sends more signals to the brain than it receives, finds that when the gut's electrical rhythm synchronizes too tightly with the brain's, that over-coupling correlates with higher rates of anxiety and depression. The gut communicates with the brain through the vagus nerve, hormones, and immune signaling, and dysbiosis or ENS dysfunction has separately been linked to mood disorders in both human and animal studies. Host Dave Asprey breaks down why the goal isn't maximum gut-brain connection but the right kind of connection, questions whether the coupling is driving the anxiety or the anxiety is driving the coupling, and makes the case for treating mood from the gut up instead of the brain down. Source: https://refractor.io/medical/enteric-nervous-system-brain-link-mental-health/ ~~ Rhonda Patrick Explains Why She Never Adds Bananas To Her Berry Smoothies Rhonda Patrick has been telling audiences she skips bananas in her berry smoothies because of polyphenol oxidase, an enzyme in bananas that degrades the polyphenols in blueberries linked to improved cognition and vascular health, based on in-vitro and food chemistry data. She now builds her smoothies on an avocado base instead, and notes that vitamin C from citrus can partially inhibit the enzyme for anyone unwilling to drop the banana. Host Dave Asprey weighs in on the gap between lab chemistry and clinical outcome data, why that gap doesn't make the mechanism any less real, and why this is a low-cost swap worth making even without a human trial behind it. Sources: https://www.reddit.com/r/Biohackers/comments/1v2jbib/dr_rhonda_patrick_i_dont_add_bananas_to_my/ https://www.foundmyfitness.com/episodes/polyphenol-oxidase-bananas-smoothies ~~ This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want mechanism-level insight into a sweetener risk hiding in everyday diet products, a heart attack predictor buried inside routine CT scans, the tradeoffs of a new cholesterol drug, a produce recall worth paying attention to, the science behind gut-driven anxiety, and a smoothie mistake that's quietly undercutting your polyphenol intake. Host Dave Asprey connects clinical research, cohort data, and food chemistry into practical frameworks for protecting brain health, cardiovascular health, and gut-brain resilience. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: artificial sweeteners cognitive decline, aspartame brain aging, tagatose safety, diet soda memory loss, myosteatosis coronary CT, skeletal muscle attenuation heart attack, SCOT-HEART trial, coronary calcium score insulin resistance, enlicitide Lipfendra FDA approval, oral PCSK9 inhibitor, LDL particle number ApoB, cyclospora outbreak 2026, Taylor Farms lettuce recall, cyclosporiasis symptoms treatment, enteric nervous system anxiety, gut brain synchronization, vagus nerve mental health, Rhonda Patrick polyphenol oxidase, banana blueberry smoothie mistake, biohacking news 2026, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Suppgrade Labs | Get real restorative sleep with Quiet Mode. Use code DAVE15 at shopsuppgradelabs.com. - EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:19 – Story 1: Artificial Sweeteners 02:05 – Story 2: Muscle Fat & Heart Risk 04:36 – Story 3: PCSK9 Cholesterol Pill 06:27 – Story 4: Cyclospora Lettuce Outbreak 07:56 – Story 5; Gut-Brain Axis & Anxiety 09:29 – Story 6: Banana vs. Blueberry 11:08 – Predictions for Next 5 Years See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. David Teitelbaum is a veterinarian and osteopathic physician who has practiced integrative and functional medicine in Fort Worth, Texas for more than 40 years. He earned his veterinary degree from Texas A&M University in 1976 and later received his Doctor of Osteopathic Medicine from the University of North Texas Health Science Center in 1984. Throughout his career, Dr. Teitelbaum has focused on helping patients achieve long-term wellness through a combination of osteopathic medicine, osteopathic manipulation, acupuncture, prolotherapy injections, and lifestyle-based approaches to health. His work emphasizes restoring function and supporting the body’s natural capacity for healing. Dr. Teitelbaum is the author of several books, including Optimal Brain Wellness, as well as two Christian books exploring faith, purpose, and spiritual growth. He continues to write and speak about lifelong health, resilience, and holistic wellness. To learn more about Dr Teitelbaum and to find his books, see www.doctor-t.com Discover more Christian podcasts at lifeaudio.com and inquire about advertising opportunities at lifeaudio.com/contact-us.

Can Infections Drive Alzheimer's? Nikki Schultek, founder of Intracel Research Group and co-founder of the Alzheimer's Pathobiome Initiative, details evidence that pathogens may contribute to Alzheimer's and other neurodegenerative and neuroimmune disorders beyond the amyloid hypothesis. Schultek recounts her own misdiagnosed systemic illness with neurodegenerative symptoms, later found to involve Lyme disease, Babesia, and chronic infection with the intracellular respiratory bacterium Chlamydia pneumoniae, treated with combination antibiotics. The discussion covers PANS/PANDAS as an infection-associated pediatric neuropsychiatric condition, parallels with neuroinflammation and blood–brain barrier changes, and a 2023 Alzheimer's & Dementia “research roadmap” documenting 86 infection-associated dementia cases and calling for actionable testing and collaboration. They review links involving herpes viruses, COVID-related cognitive decline, gum pathogen P. gingivalis therapies, and controversies around chronic infection diagnosis and long-term antibiotics, and share resources including alzpi.org, ILADS, MAPS, and Schultek's Pathobiome Research Center at PCOM.

Have you ever been told that your golden years should be about rest, only to find yourself back in the world of school runs, sports practices, and sleepless nights? Are you a grandparent raising your grandchildren, wrestling with exhaustion and identity loss, while quietly wondering if you'll ever reclaim a piece of yourself? You may be feeling the heavy weight of duty, but beneath the surface, there's a quieter transformation happening—one that science now recognizes as generativity.I'm Laura, and on this episode of 'Grandparents Raising Grandchildren: Nurturing Through Adversity,' we're flipping the script on aging. Joined by Dr. Deborah Heiser, a leading voice in developmental psychology, we discover why stepping up as a kinship caregiver might be the healthiest thing you can do for your brain. From the emotional boost of newfound purpose to the surprising cognitive benefits of mentoring a new generation, you're not just surviving—you're gaining a powerful new identity. Download her free Mental Mapping checklist here.https://mentalmapping.floot.app/You'll hear real stories of messiness and joy, practical advice for adapting to unexpected parenting, and scientific insights into the ways kinship care can stave off stagnation and loneliness. We'll talk openly about transitioning from struggle to meaning, and how embracing the joys (and the chaos) of your grandchildren revitalizes your mind, body, and legacy.Join us as we celebrate the mentors, athletes of the soul, who are nurturing through adversity and building a legacy stronger than ever before.Send us Fan MailAs a grandmother raising two grandchildren, one of my favorite things is watching them connect with the world around them. That's why I'm so in love with Dr. Dale Atkins new children's book "Dear Deer". Purchase directly through her website, Amazon or Barnes and Noble. Help our kids log off the screeens and tune back into the world! A grandmother raising grandchildren leaves a review and share her story and how every listener encourages her in her role as a kinship caregiver, one podcast at a time.Thank you for tuning into today's episode. It's been a journey of shared stories, insights, and invaluable advice from the heart of a community that knows the beauty and challenges of raising grandchildren. Your presence and engagement mean the world to us and to grandparents everywhere stepping up in ways they never imagined.Remember, you're not alone on this journey. For more resources, support, and stories, visit our website and follow us on our social media channels. If today's episode moved you, consider sharing it with someone who might find comfort and connection in our shared experiences.We look forward to bringing more stories and expert advice your way next week. Until then, take care of yourselves and each other.Want to be a guest on Grandparents Raising Grandchildren: Nurturing Through Adversity? Send Laura Brazan a message on PodMatch, here: https://www.podmatch.com/hostdetailpreview/grgLiked this episode? Share it and tag us on Facebook @GrandparentsRaisingGrandchilden Love the show? Leave a review and let us know!CONNECT WITH US: Website | Facebook 

Dr. Tommy Wood, BM, BCh, PhD, is a professor of neuroscience at the University of Washington and an expert on brain health, neuroplasticity, and cognitive performance. Dr. Wood explains how to use specific forms of exercise, dietary strategies, and compounds to enhance the rate and stability of mental and/or physical skill development. We also discuss science-based tools to preserve cognitive function, reduce dementia risk, and offset loss of memory after a concussion or other brain injury. This episode provides practical, science-based tools for learning new information and skills and for improving your overall ability to learn. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman Function: https://functionhealth.com/huberman Rorra: https://rorra.com/huberman Timestamps (00:00:00) Tommy Wood (00:04:05) Neuroplasticity; Neurogenesis; Synaptic Pruning (00:11:11) Aging & Neuroplasticity; Familiar vs Novel Tasks (00:14:33) Protocols Book; Sponsor: David (00:16:49) Aging, Training & Processing Speed (00:21:56) Enhancing Neuroplasticity with Age, Tool: Motor & Cognitive Challenge (00:26:56) Learning New Skills, Dance, Sports, Arts; Psychological Benefits of Challenge (00:36:50) Flow, Clutch States; Virtuosity (00:46:59) Power of Practice (00:50:55) Sponsor: AG1 (00:52:14) Tools for Focused Work & Learning; Distractions (01:00:17) Nutrition for Brain Health, Dementia; Critical Nutrients (01:06:56) Nutrient Timing, Supplementation; Omega-3s, Tool: Blood Tests (01:16:41) Sponsor: Function (01:18:19) Enhancing Brain Health, Nutrition & Supplements (01:23:10) GLP-1s, Peptides, Supplements & Evaluating Efficacy (01:32:56) Stimulants: Feeling vs Performance (01:37:18) Exercise & Enhancing Cognitive Function, Tool: Optimize Exercise Volume (01:43:18) Long-Term Cognitive Health & Exercise, HIIT (01:47:17) Sponsor: Rorra (01:48:31) Cortisol Benefits, Acute vs Chronic Stress (01:54:24) Resistance & Aerobic Exercise, Brain Gray & White Matter, Cognitive Health (02:03:37) Cognitive Decline, Dementia, Alzheimer's Disease, Modifiable Risk Factors (02:09:47) Shingles Vaccine & Dementia Risk; Tool: Avoid Illness for Cognitive Health (02:18:28) Concussion, Traumatic Brain Injury (TBI), Creatine (02:24:04) Treating TBI, Supplements, Physical Therapy (02:32:16) Strongman Competition (02:38:51) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Pentagon plans widespread testosterone screening for troops; New study claims arthroscopic surgery for age-related degenerative changes of knees is worthless; Widely touted “precision” proton therapy doesn't outperform conventional radiation treatment for prostate cancer; Comparing the effectiveness of gummies and liquids vs. tablet or capsule forms of supplements; Supplements to lower LDL; Lithium orotate for Alzheimer's prevention; Novel ultrasound treatment may target inflammation in osteoarthritis; Researchers explore antiviral treatments for multiple sclerosis.  

Put down the crossword puzzle and pick up the nasal spray. While those of…

Insulin resistance, chronic stress, and modern lifestyle factors contribute to Alzheimer's—Drs. Blake and Helman offer strategies to reverse these drivers. #InsulinAndBrain #StressReduction #LifestyleMedicine

Put down the crossword puzzle and pick up the nasal spray. While those of us interested in preserving our rapier wits and steel-trap memories have doubtlessly dabbled in puzzles, conversation...

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about a blood test that could predict cognitive decline before pathological signs, the use of tirofiban after tenecteplase for stroke, and the role of artificial intelligence in peer review.

In this episode of The First Day from The Fund Raising School, Bill Stanczykiewicz, Ed.D., welcomes Morgan Jessup, Director of the Walk to End Alzheimer's for the Alzheimer's Association in Indianapolis. Bill opens with a reality many fundraisers know well: some of the nonprofit sector's most generous donors are members of the Boomer and Silent generations, and normal aging can sometimes bring changes in memory, communication, and decision-making. More serious conditions, including Alzheimer's disease and other forms of dementia, can create even greater challenges. Morgan explains how the Alzheimer's Association supports families, caregivers, and communities while raising awareness and funding research through more than 600 Walk to End Alzheimer's events across the country. She also reminds listeners that these events often serve as a “front door” to services such as caregiver support groups, educational programs, and a free 24/7 helpline. Bill and Morgan then explore how fundraisers can distinguish ordinary forgetfulness from behavior that may signal a more serious concern. Misplacing keys once is one thing; repeated confusion about time or place, significant personality changes, missed commitments, inconsistent stories, or difficulty managing familiar responsibilities may warrant closer attention. Morgan encourages fundraisers to learn the Alzheimer's Association's ten warning signs and, just as importantly, to know their donors well enough to recognize meaningful changes. A single missed meeting may be nothing more than a crowded calendar doing what crowded calendars do. A consistent pattern, however, may suggest that the fundraiser should pause, observe, and consider whether the donor needs additional support. The conversation becomes especially important when a donor experiencing possible cognitive decline wants to make an unusually large gift or proposes a contribution that does not match previous behavior. Morgan advises fundraisers to respond with compassion, transparency, and a person-centered approach. That may mean gently confirming the donor's wishes, consulting trusted family members or advisers when appropriate, or seeking guidance before proceeding. She also recommends using the Alzheimer's Association's free 24/7 helpline, which is staffed by master's-level clinicians who can help callers prepare for difficult conversations and navigate questions about dementia. Bill reinforces the central ethical principle: the gift is never more important than the donor. Protecting the donor's dignity, autonomy, and well-being must remain the fundraiser's highest priority. Bill and Morgan close by emphasizing that nonprofits should not leave these situations to improvisation, crossed fingers, and a hurried hallway conversation. Organizations can prepare by including cognitive decline and donor vulnerability in gift-acceptance policies, establishing clear internal reporting procedures, and encouraging development staff to consult colleagues and leadership when concerns arise. Fundraisers should notice changes, document patterns carefully, seek expert guidance, and involve the donor's support network when appropriate. The takeaway is both practical and deeply human: fundraising is built on relationships, and those relationships require care during every stage of a donor's life. When cognitive decline enters the picture, ethical fundraising means slowing down, asking thoughtful questions, and remembering that generosity should always be met with compassion rather than pressure.

Read my writing on Substack + a private podcast: http://maximesigouin.substack.com Over 50 and ready for real body recomposition on whole-food plant-based? Book your free consultation → https://mavywellness.comSign up here to get the first lesson instantly: https://mavywellness.com/newsletterOrder a copy of my new book Forever Fit (#1 Bestseller) here - https://foreverfitbook.comDr. Noah's Linked In: https://ca.linkedin.com/in/noah-castelo-81a854131Cal Newport's books: https://calnewport.com/writing/In this episode, I sit down with Dr. Noah Costello to discuss a groundbreaking study on digital detoxes and what happens when people remove smartphone internet access for just two weeks.We explore the surprising effects on attention, mental health, and overall wellbeing, why phones impact us differently than computers, and practical strategies to regain focus in a distracted world.00:01 Can A Digital Detox Change Your Brain?04:59 Inside The Smartphone Detox Study09:00 The Surprising Results After Two Weeks17:32 Attention Gains Equivalent To 10 Years22:42 Why Imperfect Detoxes Still Work31:57 AI, Technology, And Cognitive Decline43:12 How To Start Your Own Digital Detox

Send Zorba a message!A new study shows that fast walkers in their 80s cut their risk of cognitive decline by half.Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!

Send Zorba a message!A new study shows that fast walkers in their 80s cut their risk of cognitive decline by half.Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!

Dr. Jessen returns to the podcast to take a deeper dive into subjective cognitive decline (SCD). Aiming to cover everything relating to SCD, Dr. Jessen shares insights in prognosis, risk factors and how SCD should be addressed in research and clinical practice.  Guest: Frank Jessen, MD, professor of psychiatry and psychotherapy, director, department of psychiatry, University of Cologne, clinical board member, Clinical Alzheimer's Research, German Center of Neurodegenerative Disease (DZNE), chair, European Alzheimer's Disease Consortium (EADC), founder and past chairman, ISTARRT Professional Interest Area on SCD,  SCD-initiative (SCD-I), founder, chair, German Memory Clinic Network (DNG), advisory board, German Alzheimer Association, Hirnliga Show Notes Read Dr. Jessen's study, “The characterisation of subjective cognitive decline,” on the National Library of Medicine website.  Listen to our previous episode with Dr. Jessen, “Defining Subjective Cognitive Decline,” on the Dementia Matters website or wherever you get your podcasts. Read Dr. Jessen's study, “Longitudinal Cognitive Impairment and Dementia Study (DELCODE),” on the DZNE website. Learn more about Dr. Jessen at his profile on the DZNE website. Connect with us Find transcripts and more at our website. Email Dementia Matters: dementiamatters@medicine.wisc.edu Follow us on Facebook and Twitter. Subscribe to the Wisconsin Alzheimer's Disease Research Center's e-newsletter. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer's. All donations go toward outreach and production. Learn about Dr. Chin's book, When Memory Fades: What to Expect at Every Stage, from Early Signs to Full Support for Alzheimer's and Dementia.

New data shows Alzheimer's can begin decades before symptoms. Discover early tests and lifestyle strategies to protect your brain. #AlzheimersPrevention #BrainInflammation #EarlyTesting #HealthTalks

Urolithin A (Mitopure) and Mitochondrial Renewal--Muscle, Immune, and Skin Benefits: Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline details urolithin A and Timeline's branded supplement Mitopure. She describes urolithin A's discovery through pomegranate research and worm studies showing a 45% lifespan increase. She discusses human research including improved walking distance and clinical outcomes in muscle endurance and strength. Urolithin A is presented as supporting mitochondrial health by promoting mitophagy—recycling damaged mitochondria—distinct from other mitochondrial supports like CoQ10 and NAD precursors. They explain most people cannot produce enough urolithin A from foods because only 30–40% convert precursors via the microbiome and it would require about six cups of pomegranate juice daily. Dosing discussed is 500–1,000 mg/day via gummies, capsules, or powder, with effects developing over months. She reviews emerging research on immune aging, preclinical work on brain and neurodegenerative conditions, and topical urolithin A for skin.

Subjective cognitive decline (SCD) can be one of the earliest noticeable signs of Alzheimer's disease, yet SCD is not yet fully understood. To help us understand more, Dr. Frank Jessen, an expert in the field, joins the podcast to discuss how SCD is defined, classified, and evaluated in both clinical and research settings. Guest: Frank Jessen, MD, professor of psychiatry and psychotherapy, director, department of psychiatry, University of Cologne, clinical board member, Clinical Alzheimer's Research, German Center of Neurodegenerative Disease (DZNE), chair, European Alzheimer's Disease Consortium (EADC), founder and past chairman, ISTARRT Professional Interest Area on SCD, SCD-initiative (SCD-I), founder, chair, German Memory Clinic Network (DNG), advisory board, German Alzheimer Association, Hirnliga Show Notes Read Dr. Jessen's study, “The characterisation of subjective cognitive decline,” on the National Library of Medicine website.  Learn more about Dr. Jessen at his profile on the DZNE website. Connect with us Find transcripts and more at our website. Email Dementia Matters: dementiamatters@medicine.wisc.edu Follow us on Facebook and Twitter. Subscribe to the Wisconsin Alzheimer's Disease Research Center's e-newsletter. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer's. All donations go toward outreach and production. Learn about Dr. Chin's book, When Memory Fades: What to Expect at Every Stage, from Early Signs to Full Support for Alzheimer's and Dementia.  

“The quick and the dead”: 80+ “Supermovers” show slowed cognitive decline; Dietary polyphenols help overcome vascular effects of prolonged sitting; Pros and cons of ketamine therapy for depression; Time-restricted eating alters microbiome to promote weight loss; Magnesium—what research reveals about better sleep, stress resilience, and whole-body wellness.

Autism, ADHD, and Alzheimer's rates rise with glyphosate use. Families and doctors report dramatic recovery on organic diets. #AutismRecovery #NeuroHealth #GMOImpact

How Are Protestants Navigating a Moral and Spiritual Vacuum in Evangelicalism?   Host Curtis Chang talks with former White House staffer and Atlantic columnist Pete Wehner about why Pope Leo XIV is resonating with Protestants and evangelicals despite historic theological divides. Together, they explore the Pope's moral leadership while contrasting his dignified, intellectually grounded public witness with Donald Trump's increasingly erratic influence on evangelical political culture. The conversation examines a perceived spiritual leadership vacuum within Protestantism and calls pastors, congregations, and followers of Jesus to cultivate beauty, goodness, and truth as a long-term path toward renewing Christian public witness.   00:34 - Introduction to Pope Leo XIV's Influence 02:29 - Is There a Protestant Appreciation for Catholicism? 03:59 - What Is This Pope's Impact on Public Theology? 06:06 - Papal Influence in Past Administrations 11:19 - The Collapse of Evangelical Public Theology 14:18 - Can Protestants Still Exert Moral Influence? 21:16 - The "Mad King" and Trump's Cognitive Decline 28:42 - What Can Pastors Do? 32:00 - The Importance of Beauty, Goodness, and Truth 37:08 - What Is The Pope's Transcendent Influence?   Sign up for the Anxiety Opportunity Course Use the code: Goodfaith Sign up for The After Party Sign up for The Good List   Referenced in the Episode: Pete Wehner's article "The American Pope vs. the American President"  Pete Wehner's article "The Apotheosis of Donald Trump" Pope Leo XIV's Encyclical Letter: Magnifica Humanitas The Madness of King George (YouTube free with ads) David Bentley Hart's The Beauty of the Infinite Wordsworth's The Prelude, Book 14  Good Faith's course: The After Party   Scriptures Referenced: 1 Timothy 3 (ESV) Titus 1 (ESV)   Protestant and Catholic Leaders Referenced: Pope John Paul II Pope Benedict XVI Pope Francis Reinhold Niebuhr C.S. Lewis Billy Graham Dietrich Bonhoeffer John Stott Karl Barth Oliver O'Donovan Rowan Williams Dr. Tim Keller More from Pete Wehner: Pete Wehner's articles at The Atlantic Pete Wehner's opinion pieces at The New York Times   Follow Us: Good Faith on Instagram Good Faith on X (formerly Twitter) Good Faith on Facebook   The Good Faith Podcast is a production of a 501(c)(3) nonpartisan organization that does not engage in any political campaign activity to support or oppose any candidate for public office. Any views and opinions expressed by any guests on this program are solely those of the individuals and do not necessarily reflect the views or positions of Good Faith.  

What if everything you believe about your brain inevitably slowing down with age is simply wrong, and you have far more control than you ever imagined? In this episode of The Game Changing Attorney Podcast, Michael Mogill sits down with neuroscientist, performance coach, and self-described "elite-level professional nerd" Dr. Tommy Wood to dismantle the myth that cognitive decline is destiny. Drawing on his work treating brain injury, advising Formula 1 drivers, and his new book, “The Stimulated Mind,” Dr. Wood lays out a simple framework for keeping your brain sharp at any age, and explains why the small, daily inputs matter far more than you think. For high performers running hard and recovering little, this is the wake-up call your brain has been waiting for. Here's what you'll learn: Why your brain can adapt and improve at any age, and how your expectations alone can change the outcome How to apply the three-S model (stimulus, supply, support) to protect cognitive function for life What it takes to use AI as a tool that sharpens your skills instead of quietly eroding them Your brain is not on a fixed downward path, and this episode is your blueprint for proving it. (00:00:00) Introduction (00:02:27) Becoming a Neuroscientist (00:05:32) What Is a Healthy Brain? (00:07:56) Does Aging Slow You Down? (00:11:30) The 3-S Model for Brain Health (00:17:59) Shifting the Aging Mindset (00:22:40) The Minimum Effective Dose (00:28:16) Does AI Make You Dumber? (00:36:59) Learning Faster as an Adult (00:42:38) Why Your Brain Needs Connection (00:49:56) Inside the Minds of F1 Drivers (00:55:42) Where to Start (00:57:48) Being a Game Changer ---- Links & Resources: The Stimulated Mind: Future-Proof Your Brain from Dementia and Stay Sharp at Any Age by Tommy Wood Why Brains Need Friends by Ben Rein Hintsa Performance ---- Learn what sustainable growth can look like for your firm at crispcoach.com. ---- Do you love this podcast and want to see more game changing content? Subscribe to our YouTube channel. ---- Past guests on The Game Changing Attorney Podcast include David Goggins, John Morgan, Alex Hormozi, Randi McGinn, Kim Scott, Chris Voss, Kevin O'Leary, Laura Wasser, John Maxwell, Mark Lanier, Robert Greene, and many more. ---- If you enjoyed this episode, you may also like: 461. Mastering Biological Fundamentals for Elite Performance with Dr. Kristen Holmes 364. How to Train Your Brain for Unbelievable Success 116. Steven Kotler - Harnessing Neuroscience for Peak Performance

Should you stop taking glucosamine based on a new study linking it to Alzheimer's? What's behind the spate of “Tai Chi Walking” social media posts? Undereye “festoons”—what to do about them? Are antibiotics the only treatment for SIBO? Vaping after smoking hikes risk for lung cancer.

Environmental triggers like alcohol, toxins, and negativity shape brain health more than genes. See what reversed—and triggered—cognitive decline. #BrainInflammation #Exposome #AlzheimersTriggers #HealthTalks

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're diving into some of the most exciting stories shaping the industry right now. Let's start with a groundbreaking advancement in gene therapy. Researchers have achieved a significant milestone by successfully using CRISPR technology to treat a rare genetic disorder in humans. This marks one of the first times that CRISPR has been applied directly to patients in such a way, offering hope for those suffering from conditions previously thought untreatable. This development is not just about treating one disorder; it opens up a world of possibilities for addressing various genetic diseases. By precisely editing genes at their source, scientists are paving the way for therapies that could revolutionize how we approach genetic disorders. Shifting gears to regulatory news, the FDA has granted accelerated approval to a new Alzheimer's drug that targets amyloid plaques in the brain. This drug, through its unique mechanism of action, aims to slow down cognitive decline in patients diagnosed with early-stage Alzheimer's disease. While there remains debate about the amyloid hypothesis itself, this approval signals a hopeful step forward in treating a condition that affects millions worldwide. As researchers continue to explore and understand Alzheimer's pathology, such approvals encourage further innovation and investment into neurodegenerative research. In clinical trial news, a biotech company has announced promising results from its Phase 3 trial of an mRNA-based vaccine for respiratory syncytial virus (RSV). The trial demonstrated high efficacy in preventing severe RSV infections among older adults, a population particularly vulnerable to this virus. These results not only underscore the versatility of mRNA technology but also highlight how quickly platforms developed during the COVID-19 pandemic can be adapted for other infectious diseases. This advancement suggests a future where rapid response to emerging viral threats becomes more feasible. Meanwhile, in the realm of oncology, there's been an exciting development with a novel immunotherapy showing potential in treating pancreatic cancer. This approach involves modifying patients' own immune cells to better recognize and attack cancer cells, a technique known as CAR-T cell therapy. Although traditionally successful in blood cancers, applying it to solid tumors like pancreatic cancer has been challenging due to their dense and protective tumor microenvironments. Early data indicate that this immunotherapy may penetrate these barriers more effectively, offering new hope for patients facing one of the deadliest forms of cancer. On a broader scale, the industry continues to see an increase in collaborative efforts between pharmaceutical giants and smaller biotech firms. These partnerships are essential for fostering innovation and speeding up drug development processes. By combining resources and expertise, companies can tackle complex health challenges more efficiently than ever before. Such collaborations also reflect an industry trend towards open innovation models that prioritize agility and shared knowledge over traditional competition. Finally, let's touch on an emerging trend that's capturing attention: personalized medicine's growing influence on drug development strategies. With advances in genomics and data analytics, pharmaceutical companies are increasingly tailoring therapies to individual patient profiles rather than adopting a one-size-fits-all approach. This shift not only improves treatment efficacy but also reduces the likelihood of adverse reactions, ultimately leading to better patient outcomes and more efficient healthcare systems. These stories illustrate an industry at the cutting edge of science and technology, driven by a relentless pursuit of new ways to improve human health. Each breakthrough not only represents progress but also carries profound implications for future research directions and therapeutic possibilities. That's all for today's edition of Pharma Daily. Stay tuned as we continue to bring you more updates on these exciting developments in pharmaceuticals and biotechnology. Thank you for listening, and we'll be back soon with more insights from this dynamic field.Support the show

Send us Fan MailCan listening to music help protect your brain as you age?In this episode of Causes or Cures, Dr. Eeks talks with Professor Joanne Ryan about her research on music, dementia risk, cognitive decline, and healthy aging.Drawing on data from thousands of older adults participating in the ASPREE Longitudinal Study of Older Persons (ALSOP), Professor Ryan discusses findings suggesting that frequent music engagement—including listening to music and playing a musical instrument—was associated with a lower risk of dementia and better cognitive outcomes over time.The conversation explores:• Whether listening to music can help reduce dementia risk• How playing a musical instrument may affect brain health• Proposed biological and cognitive mechanisms behind music's effects on the brain• Music, memory, and why some people with dementia can still remember and perform music• Whether certain types of music may be more beneficial than others• The limitations of observational research and what questions still remain unansweredIf you've ever wondered whether your favorite playlist is doing more than entertaining you, this episode explores what the science currently says about music, memory, cognition, and the aging brain.About Professor Joanne RyanProfessor Joanne Ryan is a Principal Research Fellow and leader of the Biological Neuropsychiatry and Dementia research team at Monash University in Australia. Her research focuses on understanding the causes, prevention, and early detection of neuropsychiatric disorders, particularly dementia and depression.Her team investigates biological, lifestyle, and environmental risk factors that influence brain health and works to identify preventive strategies that may reduce the incidence of dementia and cognitive decline. The group also studies biomarkers that may improve the timing and accuracy of diagnosis and help evaluate the effectiveness of interventions. Professor Ryan has published extensively on aging, cognition, dementia risk factors, mental health, and preventive approaches to healthy brain aging.Work with me? Perhaps we are a good match. Keep Causes or Cures Ad-Free with Listener SupportYou can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Follow on X. Follow Public Health is WeirdOr Facebook here.On Youtube.Or TikTok.SUBSCRIBE to her Newsletter here! (the bits not posted on socia media)Support the show

Last Call for Root Cause Reset! Starts June 18 --> DianeKazer.com/RCR  Join Our Elite VIP Tribe --> DianeKazer.com/VIP All Yeptide Resources ->DianeKazer.com/YEPTIDES Apply to Become a 1-on-1 Patient --> DianeKazer.com/PATIENT Can we all agree that life feels a little... extra right now? The pace of life keeps speeding up. The cost of everything seems to be going up. The news gives us 47 new reasons to feel stressed before we've even finished our morning coffee. We're literally eating and drinking 'food' with 'frenzy' energy! I'm right there with you! People are worried about their finances, their families, their future, their health and honestly... sometimes just remembering where they put their phone. (Only to realize it's in their hand.

What if protecting your brain could start with your very next meal?In this episode of Happy & Healthy with Amy, Amy explains why the MIND diet may be one of the most powerful tools you have for supporting brain health and reducing your risk of cognitive decline. Rather than focusing on one “magic” brain food, Amy walks you through how this eating pattern helps create a healthier internal environment for your one and only brain. Using Dr. Dean Sherzai's “Four Horsemen of Alzheimer's” framework, Amy breaks down four core drivers of Alzheimer's progression: glucose dysregulation, lipid dysregulation, oxidative stress, and chronic inflammation. Then she connects each one to her wildfire metaphor so you can understand why your food choices matter and how the MIND diet helps calm the conditions that make the brain more vulnerable. This is education, not medical advice. Please work with a qualified healthcare provider for decisions about your health or a loved one's care.What to Listen For[00:00] Why food is one of the most powerful levers for preventing cognitive decline [01:00] How this episode builds on episode 256 about the MIND diet [02:00] Amy's wildfire metaphor for Alzheimer's progression [04:00] The Four Horsemen of Alzheimer's: glucose, lipids, inflammation, and oxidative stress [05:30] What MIND stands for and why it is not a weight-loss diet [07:00] What the original MIND diet studies found about Alzheimer's risk [09:00] Why glucose dysregulation is like “low humidity” in the brain [13:00] How lipid dysregulation becomes the “dry brush” that affects blood flow [17:00] Why oxidative stress is like biological heat and cellular wear and tear [21:00] How chronic inflammation acts like strong winds that spread the fire [25:00] Why the MIND diet is about changing internal conditions, not perfection [28:00] How to get the printable wallet-sized MIND diet guideThe MIND diet isn't about eating perfectly. It's about consistently creating better conditions for your brain.As Amy explains, nutrition is not a cure for Alzheimer's disease, and it is not a replacement for medical care. But it is one of the most powerful tools in your prevention toolkit.RESOURCES:Book a FREE Discovery Call with AmyDownload After Mom's Alzheimer's Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

BrainStorm wants to hear from you! Send us a text.In part two of Meryl Comer's conversation with Dr. Nathaniel Chin — geriatrician, researcher, and author of When Memory Fades — they explore the practical and emotional realities of life after an Alzheimer's diagnosis. Drawing on both his clinical expertise and personal experience of caring for his father, Dr. Chin addresses the often-overlooked needs of care partners, the importance of acting quickly on legal and financial planning after diagnosis, and why lifestyle interventions matter even before seeing a specialist. The conversation also touches on the complexity of mixed dementia diagnoses, the stigma patients face, behavioral symptoms that families should anticipate, and how pre-existing relationship dynamics don't disappear; they intensify. Dr. Chin closes with an overview of the Clarity study, a national research initiative seeking participants to better understand multiple brain disease processes simultaneously. You won't want to miss this informative and personal interview!Support the show

This week's topics include visceral fat and CVD risk factors, delirium and cognitive decline and hospitalization, caps on insulin price, and factors involved with IBD.

A new Alzheimer's study linked omega-3 fish oil (EPA & DHA) supplement use to faster cognitive decline, but the real story is far more nuanced than the headlines suggest.In this discussion, cardiologist Dr. Bret Scher breaks down the study and explains why the quality, freshness, and source of omega-3s may matter more than most people realize.The study used data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and found that omega-3 supplement users experienced greater cognitive decline over five years compared to non-users. But the details matter:The study did not assess supplement quality, oxidation, dosage, or dietary habitsOxidized fish oil may behave very differently from high-quality DHA and EPAWhole food omega-3 sources like salmon, sardines, and mackerel consistently show different outcomes in researchLifestyle factors like sleep, exercise, stress, and metabolic health remain critical for brain healthOne of the biggest takeaways: supplements are not interchangeable with whole foods. And no supplement can replace the foundation of metabolic health, including nutrition, movement, sleep, stress management, and social connection.

Dr. Garth Nicolson, Founder, President, Chief Scientific Officer, and Emeritus Research Professor of Molecular Pathology at the Institute for Molecular Medicine in Huntington Beach, California, and Research Advisor for Nutritional Therapeutics, explains how membrane damage from free radicals and loss of mitochondrial transmembrane potential contribute to declining energy with age, noting studies in older adults showing improved energy output, fatigue, cognition, mood, and activity after NTFactor lipids, a protected phospholipid supplement balanced toward mitochondrial lipid composition. He describes evidence of lipid delivery using fluorescent-tagged lipids in sperm, with improved motility, and discusses applications including wound healing in veterans, removal of hydrophobic toxins via a concentration-driven “conveyor belt” process, and improved transport of nutrients like CoQ10. He details articles on normal aging, menopause-related changes supported by membranes, dementia risk linked to hearing loss, and rat studies showing delayed hearing loss with NTFactor, and mentions research on EMF sensitivity and planned schizophrenia trials.

Discover 5 key autoimmune triggers hiding in your past. From COVID and herpes simplex to staph, Epstein-Barr, and strep infections, Nurse Doza breaks down how past infections can reprogram your immune system to attack your own tissue — and what gut health has to do with it all. Gut (L-Glutamine) by MSW Nutrition Gut, featuring 4 grams of pure L-Glutamine per scoop, is the primary fuel source for the cells that line your intestinal wall. When past infections, antibiotics, or chronic stress compromise your gut barrier, your immune system loses its most important line of defense — creating the conditions where autoimmune triggers thrive. Gut helps repair the gut lining, reduce digestive inflammation, and support the immune cells that depend on a healthy gut to function properly. Whether you're managing an existing autoimmune disorder or working to prevent one, healing your gut is where it starts.

Watch as Democrats turn a serious congressional hearing into a complete circus by obsessing over Marco Rubio's shoes. This is peak Washington dysfunction. In this jaw-dropping clip, Secretary of State Marco Rubio gets grilled by a Democrat congresswoman who bizarrely brings up a pair of Florsheim shoes gifted by President Trump. Instead of focusing on foreign policy or national security, she uses the shoes as “evidence” that Rubio “can't admit facts.” Rubio's confused reaction and strong pushback perfectly highlight how unhinged and out of touch the radical Left has become. This isn't governance — it's political theater designed to embarrass conservatives while America faces real crises. Republicans understand what's really happening here: desperate Democrats attacking common-sense leaders like Marco Rubio because they have no real arguments left. We also cover: President Trump CONFIRMS phone call with Bibi. Ukrainian drone HITS St. Petersburg, Russia. Joe Biden CRASHES Dr. Jill Biden's book tour. Support for same-sex marriage flattened in the U.S. Markwayne Mullin clashes with Al Green. If you're tired of the liberal media ignoring these embarrassing moments and the nonstop circus in Washington, this video is for you. Rubio handles it with class and strength, reminding us why strong conservative leadership matters now more than ever. What do you think? Was this the most ridiculous line of questioning you've ever seen, or have Democrats gone even lower? Drop your thoughts in the comments — let's show the Left how real Americans feel about this nonsense! If you believe in truth over theater, freedom over woke politics, and common sense over circus antics, smash that LIKE button and SUBSCRIBE for more no-holds-barred coverage of the fights that matter. Turn on notifications so you never miss an upload. 00:00 Pat Gray UNLEASHED! 00:20 War Powers Vote 01:46 Why is Grok So Bad at Sports Knowledge? 03:12 Back with War Powers Vote 04:18 Congress' Schedule 07:06 Talk to your Local Congressman! 10:08 Trump on Conversation with Netanyahu 11:35 Netanyahu on Conversation with Trump 14:23 Who's Not Coming Back? 15:24 Who's Netanyahu Looking At? 16:29 Trump is Not Happy with CNN & Kaitlan Collins 18:24 Trump on Anti-Weaponization Fund 19:49 Discussing the Treatment of J6 Protestors 26:27 Did Someone Tattle on Trump? 31:09 What has Israel Done for the U.S.? 33:42 Pat Goes Biblical for a Second 34:12 Trump Defines a Ceasefire 34:58 What We Get from Israel 37:01 Ukrainian Drones Hit St. Petersburg 39:52 Fat Five 48:42 "Fancy" Walmart 50:14 Marco Rubio VS. Gregory Meeks 53:06 Marco Rubio VS. Sydney Kamlager-Dove 54:38 Marco Rubio VS. Ted Lieu 58:58 Marco Rubio on Accusations from Democrats 1:01:20 Marco Rubio & Tim McBride on Greenland 1:04:46 Ted Lieu & Trump's "Cognitive Decline" 1:07:54 Joe Biden Has a Question for his Wife 1:11:18 11 Years of Legalized LGBTQ+ Marriage/Relationships 1:19:02 Markwayne Mullin on Status of Border Wall 1:21:05 Markwayne Mullin VS. Al Green 1:24:27 Brandon Gill VS. Nickie J. Antonio 1:25:55 Discussing Illegals in America 1:33:08 Buffalo from Bangladesh that Looks like Trump Learn more about your ad choices. Visit megaphone.fm/adchoices

Can lifting weights slow how fast your brain ages?A new study used brain scans to measure exactly that. The results show that resistance training is a uniquely beneficial tool for brain health that works through different pathways than cardio.Lifting weights can make the brain test younger on functional MRI, and the benefits may keep compounding even long after you train. Learn what brain age measures, why the prefrontal cortex matters for Alzheimer's and cognitive aging, the muscle-to-brain signaling system activated by strength training, and how heavy lifting compares to moderate intensity for protecting the brain after 40. Plus a quick self-check for strength-related dementia risk, especially after 40. Enroll in Eat More Lift Heavy, the 26-week coached program where adults over 40 build the nutrition and training skills to lift heavy, build muscle, lose fat, and stay strong and sharp for decades. Timestamps:0:00 - Lifting weights and brain aging 0:47 - Dementia risk and strength training over 40 3:58 - Aerobic exercise and the hippocampus 6:00 - Prefrontal cortex and muscle signaling 7:48 - Recent study and brain age scans 10:21 - Brain age gap and dementia risk 11:30 - Results across both lifting intensities 13:12 - Myokines, irisin, and BDNF 16:57 - How to build skills for lifting weights 18:30 - Lifting protocol for brain health 20:45 - Entry points for new lifters 24:15 - Grip strength and dementia risk

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a link between higher meat and slower cognitive decline in APOE34/44 carriers, the geographic distribution of research funding, and how artificial intelligence is reshaping neurology.

What if amyloid is only the match, tau is the brush fire, and neuroinflammation is the wildfire that causes the most damage in Alzheimer's disease?In this episode of Happy & Healthy with Amy, Amy explains why researchers are paying closer attention to neuroinflammation, what may be keeping the brain's immune system stuck in the “on” position, and why midlife is such an important window for protecting your brain.You'll learn how sleep, blood sugar, chronic stress, infections, oral health, and social connection may all influence the conditions that make the brain more—or less—flammable.What to Listen For[00:00] Why amyloid may be the match—but neuroinflammation is the wildfire. [02:30] What the Cochrane review found about anti-amyloid drugs. [04:30] Why timing matters in Alzheimer's disease. [07:00] Is neuroinflammation a side effect—or a driver? [09:00] Why inflammation itself is not the villain. [11:00] Meet microglia: the brain's immune cells. [14:00] Why gum disease matters for Alzheimer's risk.[18:00] The shingles vaccine and dementia risk. [22:00] Blood sugar, insulin resistance, stress, and sleep. [29:00] How to make your brain less “flammable.” Neuroinflammation may be one of the most important pieces of the Alzheimer's prevention puzzle because it connects so many things we often treat separately: sleep, stress, blood sugar, oral health, infections, diet, and connection.Listen to the full episode to understand what may be making your brain more “flammable,” then download the free RESTORED Protocol so you can choose one simple, evidence-based next step for protecting your brain.Mentioned in The EpisodeDownload the RESTORED ProtocolDownload The First Steps Guide for supporting a parent after Alzheimer's diagnosisRelated EpisodesAlzheimer's Prevention: What the Cochrane Review MeansAlzheimer's Drugs: Why Amyloid Removal May Not Be EnoughGum Disease, Menopause & Your Alzheimer's RiskSourcesRESOURCES:Book a FREE Discovery Call with AmyDownload After Mom's Alzheimer's Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

PBD's crew torches Jill Biden's media tour as shameless gaslighting, breaking down her debate excuses, Joe's visible decline, and why a first lady clung to power while donors quietly abandon Biden's doomed presidential library

Before Your Parent's Dementia Diagnosis: 4 Things Every Family Must Do NOW (From a Daughter Who's Lived It) If you have a parent over 70, this episode could save your family $35,000, a year of your life, and the kind of stress that breaks marriages and fractures families. After four years of navigating dementia caregiving for multiple family members — including her mother-in-law with Alzheimer's, her father-in-law with vascular dementia, and now signs in her own family — Shelly Niehaus is sharing the proactive caregiving roadmap she wishes someone had handed her family before "the phone call." This is the episode every adult child with an aging parent needs to hear — before a dementia diagnosis lands in your lap. Most dementia and caregiving resources are built for families already in crisis. This one is different. This one is for the daughter, son, or spouse who has felt the flutter in their stomach but doesn't know where to start. The one quietly watching. The one quietly worrying. The one who doesn't have a plan — yet. In this deeply personal episode, Shelly walks you through the 4 areas of dementia caregiving you cannot avoid — and how to start on every single one of them today, without a diagnosis, without a family meeting, and without anyone in your family agreeing that something is wrong. In this episode, you'll learn: The Sunday phone call that changed everything: "How long do I pack for?" "I have no idea." Why the families who struggle most aren't the ones who don't love enough — they're the ones without a plan AREA 1 — Legal: Why the window to put Power of Attorney documents in place is open RIGHT NOW, and closes the moment your loved one loses capacity (and why a notarized POA is NOT the same as a complete POA) AREA 2 — Medical: Why you have to ask for a cognitive evaluation by name — and why your parent's primary care doctor probably won't bring it up AREA 3 — Financial: The slow unraveling nobody is watching, and the early sign of cognitive decline most families completely miss AREA 4 — Safety & Logistics: The conversations nobody wants to have (driving, firearms, home safety) and why naming a family quarterback BEFORE the crisis matters more than almost anything else The legal mistake that cost Mark and Shelly a year of their lives untangling frozen accounts and inaccessible Social Security The $35,000 air ambulance that could have been avoided with one earlier conversation The Truth About Watching: the 3am wake-ups, the fear, the dread, the grief that starts where the worry starts "I can't do round three. I don't have it in me." — and why Shelly is doing it anyway The one question that determines whether your family walks through this season with peace or chaos  

Dr. Marty Makary out as FDA Commissioner—was he the victim of a BigPharma purge? Are “liquid biopsies” useful for predicting recurrences, as well as guiding therapy, for cancer? Nighttime smartphone by adolescents surges, eroding kids' sleep needs; Persistent itch may require an “all of the above” approach to break its vicious cycle—could topical vitamin B12 provide an answer? Study critiques research methods that fast-tracked new Alzheimer's drugs.

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Bill Press interviews psychologist Dr. John Gartner about a new ABC/Washington Post poll finding 59% of Americans believe Donald Trump is mentally unfit for the presidency and a physicians' letter urging Trump's lawful removal due to an unsanctioned war and his sole authority over nuclear weapons. Gartner argues Trump is a “malignant narcissist” with worsening frontotemporal dementia, claiming his disinhibition, tangential speech, confabulation, language errors, and loss of social context are increasingly visible, citing clips about “SEA” vs “SEE,” a Sharpie story, and graphic remarks to schoolchildren. He links Trump's self-glorification (coins, passports, building names, images as Pope/Jesus, a triumphal arch) to delusions of grandeur and warns of escalating war and possible first-use nuclear action, doubting political checks like the 25th Amendment or Senate conviction. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It's estimated that more than 7 million Americans are living with Alzheimer's, and that number is expected to climb. Today on the podcast, Dr. Motley sits down with Dr. David Jockers of the chart-topping podcast on functional nutrition, to understand how we can nourish our bodies to help keep our brains sharp.  Learn how to tackle vitamin deficiencies through key nutritional strategies, sleep and sunlight can help address dementia and cognitive decline. This conversation is full of wisdom, including Dr. Jockers' top nutrition myths and vitamin mistakes you don't want to make.  Chapters:  00 - 13:54 - Introduction and Dr. Jockers' Morning Routine 14:00 - 22:07 - How to Prevent Alzheimer's and Dementia 22:08 - 24:29 -  Signs and Symptoms of Cognitive Decline 24:30 - 26:05 - The Role of Magnesium  26:52 - 31:07 -  Recommended Labs  31:08 - 34:47 - Look Out for Seed Oils 34:48 - 38:39 -  Tips for Healthy Cells 38:40 - 39:59 -  Biggest Nutrition Myths Out There 40:00 - 44:49 - What Exercise Does for Our Brains 44:51 - 49:23 -  Top Vitamin Mistakes People Make 49: 25 - How to Pick a Good Omega 51:03 - 57:37 - How to Learn to Fast + Why It's So Good For You ------  Follow Doctor Motley! Instagram Facebook Website Follow Dr. Jockers https://www.instagram.com/drjockers/ https://drjockers.com/ Dr. Jockers' Podcast: https://drjockers.com/radio-show/podcast/ ------  *Take the plunge into cold therapy today! Head to https://icebarrel.com/ and save $100 off Ice Barrel's and Chillers ($200 if you bundle) with code DRMOTLEY.  *Join Doctor Motley's newsletter for TCM insights and regular podcast updates: https://www.doctormotley.com/ *Do you have a ton more in-depth questions for Doctor Motley? Check out his course on emotions and the body in his membership. You'll find other courses full of his expertise and clinical wisdom, plus bring all your questions to his weekly lives! To try risk-free for 15 days click here: https://www.doctormotley.com/15

Your brain is aging faster than it should, and most of the decline is self-inflicted. Neuroscientist Dr. Tommy Wood reveals the exact mechanisms driving cognitive decay, and the biohacking strategies backed by hard science that can stop it, reverse it, and future-proof your brain at any age. -Watch this episode on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Tommy Wood, one of the most credentialed minds working at the intersection of brain optimization, human performance, and longevity. Dr. Wood holds a medical degree from the University of Oxford, a PhD in physiology and neuroscience from the University of Oslo, and serves as Associate Professor of Pediatrics and Neuroscience at the University of Washington School of Medicine. He has published over 100 scientific papers, consulted with Olympians and world champions across more than a dozen sports, and worked directly with Formula 1 drivers to sustain elite focus and reaction time at 200 miles per hour. His forthcoming book, The Stimulated Mind: Future-Proof Your Brain from Dementia and Stay Sharp at Any Age, is the culmination of decades of research and real-world application. Together, Dave and Dr. Wood dismantle the myth that cognitive decline is inevitable, exposing how societal expectations become self-fulfilling prophecies and how the tools of biohacking, including sleep optimization, neuroplasticity training, nootropics, supplements, and strategic exercise, can dramatically shift your brain's long-term trajectory. They dig into the 3S Model of brain health (Stimulus, Supply, Support), the Yerkes-Dodson arousal curve and what it means for focus and flow states, and the surprising truth about AI, boredom, and what actually happens to your brain when you let ChatGPT do your thinking for you. This episode is essential listening for anyone serious about anti-aging, brain optimization, functional medicine, metabolism, human performance, and getting smarter without working harder. You'll Learn: Why cognitive decline is largely a self-fulfilling prophecy driven by expectation, not biology How the 3S Model (Stimulus, Supply, Support) determines your brain's long-term health and resilience What Formula 1 drivers teach us about arousal, flow states, and peak cognitive performance Why high-intensity interval training produces dramatically greater neuroplasticity benefits than Zone 2 cardio alone How creatine, nicotine, nootropics, and other supplements actually affect the aging brain The real data on alcohol, dementia risk, and what "occasional drinking" actually means scientifically How to use AI tools like ChatGPT in a way that builds brain function instead of destroying it Why boredom is a neurological necessity and how chronic low-level stimulation is quietly eroding your cognition What mitochondria and lactate signaling have to do with BDNF and long-term memory How resistance training, coordinative movement, and blood flow restriction each deliver separate and distinct cognitive benefits Thank you to our sponsors! - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - Neuronic | Go to www.neuronic.online Code DAVE for $100 off - Danger Coffee | Grab yours at DangerCoffee.comand use code DAVEPOD at checkout for 15% off. - Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Tommy Wood, The Stimulated Mind, brain health, cognitive decline, dementia prevention, neuroplasticity, brain optimization, biohacking, Dave Asprey, human performance, longevity, 3S model, brain stimulation, headroom, cognitive reserve, BDNF, lactate, Zone 2, HIIT, resistance training, blood flow restriction, sleep optimization, nootropics, creatine, nicotine, acetylcholine, supplements, ADHD, arousal curve, flow state, Formula 1, anti-aging, mitochondria, metabolism, AI and the brain, ChatGPT, digital dementia, boredom, neurogenesis, hippocampus, white matter, IGF-1, osteocalcin, alcohol and dementia, TMS, TDCS, vagal nerve stimulation, near infrared light, functional medicine, cognitive stimulation, stereotype embodiment theory Resources: • Learn More About Tommy And His Work At His Website: https://www.drtommywood.com • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 — Trailer 01:28 — Guest Intro: Dr. Tommy Wood 03:37 — F1 Drivers & Arousal Optimization 09:01 — Brain Headroom & the 3S Model 13:14 — Brain Stimulation Tech (TMS, TDCS) 17:50 — Cognitive Decline & Aging 20:55 — Alcohol & Brain Health 24:10 — ADHD & Brain Chemistry 26:53 — Nicotine & Cognitive Enhancement 33:25 — Creatine for the Brain 35:12 — Zone 2 vs. High-Intensity Exercise 39:19 — Strength Training & Brain Benefits 43:12 — Boredom & Cognitive Resilience 45:06 — AI & Brain Health 52:49 — Future-Proofing Your Brain See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.