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Featuring articles on transcatheter repair for tricuspid regurgitation, rifapentine in household contacts of persons with leprosy, peresolimab for rheumatoid arthritis, and emodepside for T. trichiura and hookworm infections; a review article on tricuspid regurgitation; a case report of a man with paresthesia of the arms and legs; and Perspective articles on advancing community living for people with disabilities, on essential steps for abolishing disability injustice, and on the thin pane.
Ever thought about asking a member of Parliament how to become Prime Minister? Moira Clay, a leading research strategist, asked that very question, and she's now cultivated a career helping leaders in health and medical research make an impact in both research and the community.Join us as we speak with Moira about her journey in medical research, and developing a holistic and comprehensive approach to cancer treatment.About Professor Moira Clay Professor Moira Clay is one of Australia's foremost experts in research strategy. She is a transformational leader and a highly experienced facilitator, with an extensive knowledge of the changing research agenda. She has a reputation for professionalism and integrity and is known for her collaborative and inclusive approach. Moira has extensive senior executive experience in research institutes in Victoria, NSW and WA - including 6 months as Acting Director of the Telethon Kids Institute. She was President of two peak bodies – the Australian Society for Medical Research (2003) and Australasian Research Management Society (ARMS) (2013), leading significant public, political and scientific advocacy initiatives. In 2018, she was nominated as a Fellow of ARMS, acknowledging her enduring and substantial contributions to research management, and her active philanthropic involvement was profiled in a TEDx Fremantle talk. In 2011, she completed the Eureka Institute International Certificate in Translational Medicine. She is currently the Chair of the Advisory Board of the Menzies Institute.Moira founded Moira Clay Consulting in 2013, propelled by her drive to help Australian health and medical research leaders achieve transformative health benefits for the community. MCC has built a strong reputation for adding value to health and medical research organisations (including medical research institute's; hospitals, funding bodies; universities; peak bodies and major initiatives) across Australia.Show Notes (link)[00:00:45] Moira's beginnings in biochemistry.[00:01:51] Developing the foundations for the work Moira does now during her PhD.[00:03:21] Exploring the world through postdoctoral research.[00:04:17] Moira's career crisis that led her to think bigger.[00:05:40] How does one become Prime Minister?[00:08:32] We ultimately want to make things better.[00:10:28] Co-design, and how medical research strategy can make an impact.[00:16:49] A stretched workforce needs greater collaboration.[00:19:29] The shift to cancer research.[00:22:25] Starting a consultancy.[00:23:23] The Pirate Ship Foundation.[00:24:16] West Australian Comprehensive Cancer Centre: The need for comprehensive cancer care.[00:30:45] Honeybee Venom Research by Dr Pilar Blancafort and Dr Ciara Duffy.[00:32:09] West Australian Comprehensive Cancer Centre.[00:33:56] Exercise for reduction of cancer risk and treatment efficacy.[00:38:18] What advice you would give someone who wants to do what you do? Or what advice should they ignore?Connect with STEAM PoweredWebsite | YouTube | Facebook | Instagram | Twitter |
Featuring articles on anti-CD20 antibodies and venetoclax in chronic lymphocytic leukemia, epicutaneous immunotherapy in toddlers with peanut allergy, cabozantinib in advanced renal-cell carcinoma, and racial inequality in the receipt of medications for opioid use disorder; a review article on HPV vaccination; a case report of a man with redness of the right eye; and Perspective articles on addressing serious illness care in Medicare Advantage, on corporate citizenship and institutional responses post-Dobbs, and on ethical conflicts for clinicians under Tennessee abortion law.
Psychedelic drugs have long been been used for their mind-altering effects. Now, they are making their way into western medicine as a treatment for mental health disorders. From July, psychiatrists in Australia will be able to prescribe MDMA for post-traumatic stress disorder, making it the first country in the world to recognise psychedelics as medicines. The US could soon follow, with plans for the US Food and Drug Administration to be asked for approval to treat PTSD with MDMA this year. Ian Sample speaks to correspondent Hannah Devlin about how the science behind psychedelic therapy has progressed, and hears from Prof Celia Morgan about what treatment is actually like, what we know about the risks and what's left to learn. Help support our independent journalism at theguardian.com/sciencepod
TheSugarScience Podcast- curating the scientific conversation in type 1 diabetes
In this episode, Eric Chang joins us to discuss making brain-body and neuro-immune connections with the vagus nerve. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!
Join John Welbourn, Jud Kauffman, and Dr. Kirk Parsley on Fridays. This week - discussing protein! This week's guests: - Judson Kauffman: Former Navy SEAL and serial entrepreneur, Jud's mission is to help others find fulfillment and maximize their individual potential in order to have the greatest positive impact on the world. Jud is a speaker, coach, and advisor. - Dr. Kirk Parsley, M.D.: Kirk has worked with elite performers and the SOF community on all aspects of performance and resilience since 2009. He was our Medical Research team lead in the Triple 7 expedition and helped the jumpers prepare physically and mentally also helped them manipulate their sleep schedule for improved performance and stress mitigation and - John Welbourn: John is a former American football offensive tackle and guard and the creator and operator of Power Athlete HQ. This performance-based programming transforms athletic potential into real-world results. Our Power Hours will allow you to ask questions in real time!
In this week's episode we'll review imbalances in gut microbiota may impact the efficacy and safety of immunochemotherapy in patients with diffuse large B-cell lymphoma. Next, the NFIA-ETO2 fusion, found exclusively in pediatric patients with pure erythroid leukemia, impairs the normal process of erythroid differentiation. Finally, we'll look at the effectiveness of nirmatrelvir plus ritonavir in patients with CLL infected with SARS-CoV-2 during the Omicron surge.
This week, Jeremy talks to Dr. Paul Larkin, director of research at The ALS Association, and Dr. Frank Bennett, Chief Scientific Officer at Ionis and a pioneer in the field of antisense oligonucleotide research, about the FDA's approval of tofersen and the future of ALS drug development. To learn more about why the FDA's decision on tofersen matters to everyone, check out: https://www.als.org/blog/tofersen-approved-sod1-als For more information on antisense technology go to: https://www.als.org/research/research-we-fund/scientific-focus-areas/genetics/antisense-therapy-for-alsThis episode is brought to you The ALS Association in partnership with CitizenRacecar.
For the first time, researchers have found a way to non-invasively translate a person's thoughts into text. Using fMRI scans and an AI-based decoder trained on a precursor to ChatGPT, the system can reconstruct brain activity to interpret the gist of a story someone is listening to, watching or even just imagining telling. Ian Sample speaks to one of the team behind the breakthrough, the neuroscientist Dr Alex Huth, to find out how it works, where they hope to use it, and whether our mental privacy could soon be at risk. Help support our independent journalism at theguardian.com/sciencepod
What is the actual truth behind cannabis harms and benefits? Dr. Peter Grinspoon, Instructor in Medicine at Harvard Medical School and author of "Seeing Through the Smoke: Cannabis: An Expert Doctor Untangles the Truth About Cannabis," shares his expertise on various topics related to cannabis. From the challenges of having non-judgmental conversations about cannabis between doctors and patients to the potential benefits and harms of cannabis, Dr. Grinspoon provides valuable insights across the board including.The Government's funding into cannabis research: harms vs. BenefitsThe process of re-legalizing cannabis and how it affects institutional knowledge.The truth behind the gateway theory of cannabisHis Perspective on Andrew Huberman Podcast The potential for cannabis addiction and how it's been greatly exaggeratedThe urgent need to teach the endocannabinoid system in medical schoolsA must-listen Rapid Fire Guest Links https://www.petergrinspoon.com/Buy his book Amazonhttps://twitter.com/Peter_Grinspoonhttps://www.instagram.com/peter_grinspoon/Follow us: Our Links.At Eighth Revolution (8th Rev), we provide services from capital to cannabinoid and everything in between in the cannabinoid industry.8th Revolution Cannabinoid Playbook is an Industry-leading report covering the entire cannabis supply chain The Dime is a top 5% most shared global podcast The Dime is a top 50 Cannabis Podcast Sign up for our playbook here:
What is the actual truth behind cannabis harms and benefits? Dr. Peter Grinspoon, Instructor in Medicine at Harvard Medical School and author of "Seeing Through the Smoke: Cannabis: An Expert Doctor Untangles the Truth About Cannabis," shares his expertise on various topics related to cannabis. From the challenges of having non-judgmental conversations about cannabis between doctors and patients to the potential benefits and harms of cannabis, Dr. Grinspoon provides valuable insights across the board including.The Government's funding into cannabis research: harms vs. BenefitsThe process of re-legalizing cannabis and how it affects institutional knowledge.The truth behind the gateway theory of cannabisHis Perspective on Andrew Huberman PodcastThe potential for cannabis addiction and how it's been greatly exaggeratedThe urgent need to teach the endocannabinoid system in medical schoolsA must-listen Rapid Fire Guest Links https://www.petergrinspoon.com/Buy his book Amazonhttps://twitter.com/Peter_Grinspoonhttps://www.instagram.com/peter_grinspoon/Follow us: Our Links.At Eighth Revolution (8th Rev), we provide services from capital to cannabinoid and everything in between in the cannabinoid industry.8th Revolution Cannabinoid Playbook is an Industry-leading report covering the entire cannabis supply chain The Dime is a top 5% most shared global podcast The Dime is a top 50 Cannabis Podcast Sign up for our playbook here:
Featuring articles on interrupting therapy to attempt pregnancy after breast cancer, trifluridine–tipiracil and bevacizumab in colorectal cancer, imaging- or angiography-guided PCI for complex lesions, and idiopathic CD4 lymphocytopenia; a review article on neonatal seizures; a Clinical Problem-Solving describing a diagnostic sequence; and Perspective articles on combating West Nile virus disease, on falling insulin prices, on next steps in policy reforms to address the overdose crisis, and on the breast biopsy and the Buddhist half-smile.
On May's JHLT: The Podcast, we feature two manuscripts from the May issue of The Journal of Heart and Lung Transplantation. First, the editors explore a study entitled “Donor hyperoxia is a novel risk factor for severe cardiac primary graft dysfyunction,” which comes from Kransdorf and colleagues at Cedars Sinai Medical Center in Los Angeles. The editors welcome first author Evan Kransdorf, MD, PhD, to share how he transitioned from oncology to heart failure and transplantation, and to talk about the findings of the study. The Digital Media Editors want to know how machine learning came to be a part of the study, what other donor-specific predictors might contribute to severe PGD, and whether DCD and DBD donors had different outcomes. Next, the editors welcome first author Danny Ramzy, MD, PhD, from the UTHealth McGovern School of Medicine in Houston to discuss the paper, “Improved clinical outcomes associated with the Impella 5.5 compared to the Impella 5.0 in contemporary cardiogenic shock and heart failure patients.” The digital media editors dig in with Dr. Ramzy on why Impella 5.5 has better outcomes and if this outcome holds in multivariable models, why the survival outcomes were so much higher than published survivals for patients with cardiogenic shock, and what follow up studies might get the answers they're looking for. Follow along at www.jhltonline.org/current, or, if you're an ISHLT member, log in at ishlt.org/journal-of-heart-lung-transplantation. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
Research studies are designed to investigate the details of our bodies and lives. The research process has the potential to point out how our disability limits us. This can be tough to take. That's why it's important to recognize the emotional response to research. In this Episode: Kyle left the house to get pants. You Got This, Mental Health featuring Heidi Behr - You might remember our friend Heidi from Episode 182 - Comparing Ted Lasso To Reality. Heidi returns to talk about JOY and how we find our way there. The Dudes discuss the emotional response to the use of assistive technology. Emotions can get heavy when we think about the need for these things. Thank you notes - Kyle's Socks and Friends that help move stuff Links and Resources: Branding Science Heidi Behr, LCSW, MSW, MPH This episode brought to you in part by Reata Pharmaceuticals. Reata Pharmaceuticals is the company that makes SKYCLARYS™ (omaveloxolone) 50 mg capsules. Our mission is to develop innovative therapies that change patients' lives for the better. For more information about SKYCLARYS, visit: Skyclarys.com ©2023 Reata Pharmaceuticals, Inc. All rights reserved. SKYCLARYS, REATA, and their logos are trademarks of Reata Pharmaceuticals, Inc.
Join Mike, Dr. Kirk Parsley, and the team LIVE on Fridays. This week - discussing healthy sleep habits! This week's guests: - Dr. Kirk Parsley, M.D.: Kirk has worked with elite performers and the SOF community on all aspects of performance and resilience since 2009. He was our Medical Research team lead in the Triple 7 expedition and helped the jumpers prepare physically and mentally also helped them manipulate their sleep schedule for improved performance and stress mitigation and - John Welbourn: John is a former American football offensive tackle and guard and the creator and operator of Power Athlete HQ. This performance-based programming transforms athletic potential into real-world results. - Sean Apperson: Sean is the President of Archetype Boxing, a Silver Certified USA Boxing Coach, a lifelong Mixed Martial Artist, and Paragon Academy Owner and Operator for 13 years. Sean's goal with Archetype is to help the students leave their comfort zone, take new risks, and slowly grow into a stronger version of themselves. - Judson Kauffman: Former Navy SEAL and serial entrepreneur, Jud's mission is to help others find fulfillment and maximize their individual potential in order to have the greatest positive impact on the world. Jud is a speaker, coach, and advisor. Hosted by Mike Sarrialle.
In the first hour of "Connections with Evan Dawson" on Thursday, April 27, 2023, we discuss what people participating in medical research need to know.
In this week's episode, we'll discuss the newly revised International Working Group response criteria for patients with higher-risk MDS, learn more about the utility of machine learning in the differential diagnosis of bone marrow failure, and discuss whether patients with the Asian-type DEL allele, who type as serologic Rh-D-negative, can be safely transfused with RhD-positive blood.
We are exploring the Guardian Long Read archives to bring you some classic pieces from years past, with new introductions from the authors. This week, from 2020: After losing four pregnancies, Jennie Agg set out to unravel the science of miscarriage. Then, a few months in, she found out she was pregnant again – just as the coronavirus pandemic hit. Help support our independent journalism at theguardian.com/longreadpod
Featuring articles on a 15-year follow-up of prostate cancer therapies, on deciphering developmental disorders, blinatumomab in infant acute lymphoblastic leukemia, and a BCG vaccination against Covid-19; a review article on advances in AI for infectious-disease surveillance; a case report of a woman with abdominal pain and jerking movements; and Perspective articles on access to biomedical innovation, on helping people stop smoking, and on racial affinity group caucusing in medical education.
This week's guests: - Dr. Kirk Parsley, M.D.: Kirk has worked with elite performers and the SOF community on all aspects of performance and resilience since 2009. He was our Medical Research team lead in the Triple 7 expedition and helped the jumpers prepare physically and mentally also helped them manipulate their sleep schedule for improved performance and stress mitigation and - John Welbourn: John is a former American football offensive tackle and guard and the creator and operator of Power Athlete HQ. This performance-based programming transforms athletic potential into real-world results. - Sean Apperson: Sean is the President of Archetype Boxing, a Silver Certified USA Boxing Coach, a lifelong Mixed Martial Artist, and Paragon Academy Owner and Operator for 13 years. Sean's goal with Archetype is to help the students leave their comfort zone, take new risks, and slowly grow into a stronger version of themselves. And special guest: - Dr. Christopher Frueh: Chris is a clinical psychologist, Professor of Psychology at the University of Hawaii, and Clinical Professor of Psychiatry, at the University of Texas Health Science Center, Houston, TX. He has thirty years of professional experience working with military veterans and active-duty personnel. Hosted by Mike Sarraille
In this episode Associate Editor, Dr. Mario Cazzola discusses the review series on Classical Myeloproliferative Neoplasms, with authors, Dr. Ann Mullaly and Dr. Alison Moliterno.
In this week's episode we will review treatment and outcomes for patients with autoimmune hemolytic anemia during pregnancy. Next, rapid immune tolerance induction in patients with hemophilia A and high-titer inhibitors. Finally, researchers compare kinetics and cell cycle progression in hematopoietic stem cells from cord blood, young adults, and aged healthy donors.
Featuring articles on an RSV vaccine in pregnancy, an RSV vaccine in older adults, sotatercept for pulmonary arterial hypertension, the burden of typhoid and paratyphoid fever in India, cerebral oximetry in extremely preterm infants, and on immune checkpoint inhibitors; a case report of a woman with muscle weakness and myalgia; and Perspective articles on wastewater surveillance for infectious disease, on exacerbating health inequity, and on the breast or bottle.
Johns Hopkins University professor Dr. Marty Makary once again joins John Oakley to talk criticize our governments' stubborn refusal to "follow the science" with respect to COVID-19 restrictions. You can listen to the John Oakley Show live and in its entirety weekdays from 3:00 - 6:00pm ET over the air, or on our website www.640toronto.com Got a question a question or comment? We'd love to hear from you at michael@640toronto.com Music for the John Oakley Show podcast composed and produced by Michael Downey Learn more about your ad choices. Visit megaphone.fm/adchoices
Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School, Senior Scientist at Brigham and Women's Hospital, and Co-Director of the Center for Infection and Immunity, at the Brigham Research Institutes, Boston. He is also an associate member of the Broad Institute, and a participant in a Klarman Cell Observatory project that focuses on T cell differentiation. He is the founding Director of the Evergrande Center for Immunologic Diseases at Harvard Medical School and Brigham and Women's Hospital. His major research interests include autoimmune diseases—particularly the role of co-stimulation—the genetic basis of experimental autoimmune encephalomyelitis and multiple sclerosis, as well as cell surface molecules and regulatory factors that regulate the induction of T cell tolerance and dysfunction. His laboratory bred several transgenic mice that serve as animal models for human multiple sclerosis. The Kuchroo laboratory was also the first to describe the TIM family of genes, and identified Tim-3 as an inhibitory receptor expressed on T cells, which is now being exploited for cancer immunotherapy. He was first to describe the development of highly pathogenic Th17 cells, which have been shown to induce multiple different autoimmune diseases in humans. Kuchroo is the lead author on a paper describing the development of Th17, which is one of the most cited papers in the field of Immunology.Kuchroo came to the United States in 1985, as a Fogarty International Fellow at The National Institutes of Health, Bethesda, MD for one year, before joining the department of pathology at Harvard Medical School, as a research fellow. Later, he joined the Center for Neurologic Diseases at Brigham and Women's Hospital as a junior faculty member in 1992.He obtained his degree in Veterinary Medicine from the College of Veterinary Medicine, Hisar, India. Subsequently, he specialized in pathology at the University of Queensland, Brisbane Australia, where he obtained a Ph.D. in 1985. He received the Fred Z. Eager Research Prize and medal for his Ph.D. research work at the University of Queensland. Based on his contributions, he was awarded the Javits Neuroscience Award by the National Institutes of Health in 2002 and the Ranbaxy prize in Medical Research from the Ranbaxy Science Foundation in 2011. He was named Distinguished Eberly Lecturer in 2014, and obtained a Nobel Laureate Peter Doherty Lecture/Prize in 2014.Kuchroo has 25 patents and has founded 5 different biotech companies including CoStim Pharmaceuticals and Tempero Pharmaceuticals. He also serves on the scientific advisory boards and works in advisory capacity to a number of internationally recognized pharmaceutical companies including: Biocon, Syngene, Pfizer, Novartis and Glaxo-Smith-Klein (GSK).Alix Ventures, by way of BIOS Community, is providing this content for general information purposes only. Reference to any specific product or entity does not constitute an endorsement nor recommendation by Alix Ventures, BIOS Community, or its affiliates. The views & opinions expressed by guests are their own & their appearance on the program does not imply an endorsement of them nor any entity they represent. Views & opinions expressed by Alix Ventures employees are those of the employees & do not necessarily reflect the view of Alix Ventures, BIOS Community, affiliates, nor its content sponsors.Thank you for listening!BIOS (@BIOS_Community) unites a community of Life Science innovators dedicated to driving patient impact. Alix Ventures (@AlixVentures) is a San Francisco based venture capital firm supporting early stage Life Science startups engineering biology to create radical advances in human health.Music: Danger Storm by Kevin MacLeod (link & license)
Join America's Roundtable (https://americasrt.com/) radio co-hosts Natasha Srdoc and Joel Anand Samy with one of the nation's leading entrepreneurs and philanthropists — Bernie Marcus, co-founder of The Home Depot. The Home Depot employs over 500,000 associates at 2,300 stores and is one of the most recognized and admired companies in the world. As Chairman of The Marcus Foundation, Bernie Marcus has gifted more than $2 billion for medical research and facilities, military veterans, Israel, autism and community enhancement. Bernie Marcus is a strong supporter of capitalism — the free-enterprise system, democracy and America. On America's Roundtable, Bernie Marcus shares his life story, featured in his book titled, "Kick Up Some Dust: Lessons on Thinking Big, Giving Back, and Doing It Yourself." americasrt.com (https://americasrt.com/) https://ileaderssummit.org/ | https://jerusalemleaderssummit.com/ America's Roundtable on Apple Podcasts: https://podcasts.apple.com/us/podcast/americas-roundtable/id1518878472 Twitter: @HomeDepot @ileaderssummit @AmericasRT @NatashaSrdoc @JoelAnandUSA @supertalk America's Roundtable is co-hosted by Natasha Srdoc and Joel Anand Samy, co-founders of International Leaders Summit and the Jerusalem Leaders Summit. America's Roundtable (https://americasrt.com/) radio program - a strategic initiative of International Leaders Summit, focuses on America's economy, healthcare reform, rule of law, security and trade, and its strategic partnership with rule of law nations around the world. The radio program features high-ranking US administration officials, cabinet members, members of Congress, state government officials, distinguished diplomats, business and media leaders and influential thinkers from around the world. Tune into America's Roundtable Radio program from Washington, DC via live streaming on Saturday mornings via 65 radio stations at 7:30 A.M. (ET) on Lanser Broadcasting Corporation covering the Michigan and the Midwest market, and at 7:30 A.M. (CT) on SuperTalk Mississippi — SuperTalk.FM reaching listeners in every county within the State of Mississippi, and neighboring states in the South including Alabama, Arkansas, Louisiana and Tennessee. Listen to America's Roundtable on digital platforms including Apple Podcasts, Spotify, Amazon, Google and other key online platforms. Listen live, Saturdays at 7:30 A.M. (CT) on SuperTalk | https://www.supertalk.fm
In this week's episode, we'll learn how rare germline genetic variants in complement factor H (CFH) affect the course of paroxysmal nocturnal hemoglobinuria, discuss the role of coagulation factor XII in thrombotic complications and vaso-occlusion associated with sickle cell disease, and learn more about the overlapping features of therapy-related and de novo NPM1-mutated AML.
Featuring articles on bempedoic acid in statin-intolerant patients, tranexamic acid to prevent hemorrhage after cesarean delivery, an oral melanocortin receptor agonist in porphyria, the influence of blood-donor sex on recipient mortality, and on air pollution, mortality, race, and social class; a review article on screening for prostate cancer; a case report of a man with mantle-cell lymphoma and hypoxemia; and Perspective articles on the courts' disregard for women's health and safety, on care integration for dually eligible beneficiaries, and on treating chronic pain in sickle cell disease.
In this week's episode we will review optimizing the value of post-transplant lenalidomide maintenance in multiple myeloma. Next, T-cell immunotherapies targeting AML antigens upregulate MHC Class II expression on AML cells. Finally, young bugs rejuvenate old blood: transplanting fecal microbiota from younger mice into older mice improved hematopoietic stem cell function and restored lymphoid differentiation potential.
In this episode, Clint has a conversation with Dr. Olga Kubassova, founder and CEO of Image Analysis Group (IAG). During their chat, Olga discusses the origins of IAG, shares her thoughts about A.I. – especially in regard to drug development – and talks about the highs and lows of being a founder-CEO. Plus, Dr. Kubassova tells Clint about pursuing two PhDs at the same time in two different countries. This is the first part of a two-part discussion.
Featuring articles on thrombectomy for large ischemic strokes, CAR T cells for relapsed or refractory neuroblastoma, postexposure doxycycline to prevent bacterial STIs, and the genetic risk of low-grade glioma; a review article on primary Budd–Chiari syndrome; a Clinical Problem-Solving on an alternate explanation; and Perspective articles on ensuring public trust in an empowered FDA, on why diverse clinical trial participation matters, and on a quixotic quest for independence.
In this episode, Dr. Brittany Barreto talks to Professor Christine Metz, Co-Director of The ROSE Study. They discuss menstrual effluent, what it is, how it can be used as a diagnostic tool and what this means for people with endometriosis. This is an awesome episode - let us know what you think!Remember to like, rate and subscribe and enjoy the episode!Guest bioDr. Christine N Metz is a Professor at the Feinstein Institutes for Medical Research at Northwell Health and the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. Her research primarily focuses on identifying mechanisms that underlie dysfunctional inflammatory responses. Most of this work centers on women's health. Dr. Metz is the author of more than 160 peer-reviewed scientific research papers and more than a dozen review articles and book chapters. She was recently recognized as one of the top 100,000 scientists in the world (among 7 million) based on her productivity and the impact of her work (PLoS Biology, 2019). Company bioThe ROSE study was developed in 2013 by Peter K Gregersen, MD and Christine N Metz, PhD, who serve as co-directors. The ROSE study enrolls menstruators ages 15-50 years to participate in research studies focused on using menstrual effluent (or menstrual blood) as a tool to study endometriosis (as well as as other uterine-health disorders). We are focused on 1) developing non-invasive methods for screening/diagnosing endometriosis (as well as uterine-health disorders) to reduce the delay in diagnosis and 2) better understanding endometriosis to develop more effective and tolerable treatments, which are sorely needed.FemTech Focus Podcast bioThe FemTech Focus Podcast is brought to you by FemHealth Insights, the leader in Women's Health market research and consulting. In this show, Dr. Brittany Barreto hosts meaningfully provocative conversations that bring FemTech experts - including doctors, scientists, inventors, and founders - on air to talk about the innovative technology, services, and products (collectively known as FemTech) that are improving women's health and wellness. Though many leaders in FemTech are women, this podcast is not specifically about female founders, nor is it geared toward a specifically female audience. The podcast gives our host, Dr. Brittany Barreto, and guests an engaging, friendly environment to learn about the past, present, and future of women's health and wellness.FemHealth Insights bioLed by a team of analysts and advisors who specialize in female health, FemHealth Insights is a female health-specific market research and analysis firm, offering businesses in diverse industries unparalleled access to the comprehensive data and insights needed to illuminate areas of untapped potential in the nuanced women's health market.Time Stamps[04:03] Professor Metz's background[06:59] What is endometriosis?[08:09] The ROSE Study[10:02] Progress in understanding endometriosis[10:53] Menstrual Effluent[12:55] The uterus is not a closed system[14:25] Research on Menstrual Effluent[17:36] How to collect Menstrual Effluent[20:23] Study findings so far[22:49] How to get involved[25:37] How quickly could a diagnosis be given with the tool?[26:15] How soon could a tool be on the market?[29:32] Attitudes to studying menstrual effluent[32:19] Funding for endometriosis research[34:23] What would be the impact if we could diagnose endometriosis earlier?[36:00] Current endometriosis treatments[38:33] What is an area of women's health and wellness that still needs innovating?[39:55] Potential law changes in Florida and the impact for endometriosis[41:22] What does the femtech industry as a whole need the most to be successful?Call To Action!Make sure you subscribe to the podcast, and if you like the show please leave us a review!Episode ContributorsProfessor Christine MetzLinkedIn: @Christine MetzTwitter: @CN_METZ The ROSE StudyWebsite: https://feinstein.northwell.edu/institutes-researchers/institute-molecular-medicine/robert-s-boas-center-for-genomics-and-human-genetics/rose-research-outsmarts-endometriosisEmail: rose@northwell.edu Feinstein Institutes for Medical Research, Northwell HealthWebsite: https://feinstein.northwell.edu/LinkedIn: @Northwell HealthTwitter: @northwellhealthInstagram: @northwellhealthYoutube: @NorthwellHealth Dr. Brittany BarretoLinkedIn: https://www.linkedin.com/in/brittanybarreto/Twitter: @DrBrittBInstagram: @drbrittanybarreto FemTech Focus PodcastWebsite: https://femtechfocus.org/LinkedIn: https://www.linkedin.com/company/femtechfocusTwitter: @FemTech_FocusInstagram: @femtechfocus FemHealth InsightsWebsite: https://www.femhealthinsights.com/LinkedIn: @FemHealth Insights
JAMA Editor-in-Chief Kirsten Bibbins-Domingo, MD, PhD, joins to discuss the latest developments in medical research and trending topics from The Journal of the American Medical Association. American Medical Association CXO Todd Unger hosts.
In this week's episode we'll learn how HLA-E-restricted immune responses help control Epstein-Barr virus infection, discuss the activity of NRX-0492 in chronic lymphoblastic leukemia, and learn more about the efficacy of non-steroid inflammatory drugs in the treatment of bone marrow failure associated with Ghosal Hematodiaphyseal Dysplasia.
In this bonus episode Associate Editor, Dr. Mario Cazzola discusses the review series on Germline predisposition to hematologic malignancies with authors, Dr. Lucy Godley, Dr. Anna Brown, and Dr. Dennis Hickstein.
Featuring articles on azithromycin to prevent sepsis or death during birth, transcatheter arterialization for limb ischemia, gene–environment interactions and the risk of gastric cancer, vedolizumab for the treatment of chronic pouchitis, a general AI chatbot for medicine, and on dark-alley ethics; a review article on artificial intelligence and machine learning in clinical medicine, 2023; a case report of a man with convulsions; and Perspective articles on the end of a declared public health emergency, on medication-associated diethylene glycol mass poisoning, and on digital minimalism.
Madeleine Finlay hears from science correspondent Linda Geddes about her experience becoming a faecal transplant donor, how getting a dose of someone else's gut bacteria could treat illnesses like arthritis, diabetes and cancer, and asks whether a pill made from poo is an idea we are ready to swallow. Help support our independent journalism at theguardian.com/sciencepod
Episode: 2951 Scurvy, Vitamin C, and the Origins of the Modern Clinical Trial. Today, we go to sea.
In this episode of Lung Cancer Considered, host Dr. Stephen Liu moderates a conversation about small cell lung cancer and previews the upcoming IASLC 2023 Hot Topic Meeting: Small Cell Lung Cancer in April which is focused on both preclinical and clinical advances in small cell lung cancer research. Joining the conversation are Alvaro Quintanal-Villalonga, PhD., from the Rudin Lab at Memorial Sloan Kettering Cancer Center in New York, and Kate Sutherland, PhD., from the Walter and Eliza Hall Institute of Medical Research in Australia.
Power Hour with Brent Smith: Shinedown 2023 Tour, IV Drip Therapy and Recovery This week's guests: - Brent Smith: Brent is the lead vocalist and songwriter of the multiplatinum rock band Shinedown. The band's acclaimed album Planet Zero is out now, featuring their hit song “A Symptom of Being Human.” Shinedown has more than 6.5 billion global streams, 19 #1 rock hits, 15 platinum and gold singles, platinum or gold certification for every album, 10 million albums sold worldwide, and the most #1s ever in the history of the Billboard Mainstream Rock Songs Chart. - Dr. Kirk Parsley, M.D.: Kirk has worked with elite performers and the SOF community on all aspects of performance and resilience since 2009. He was our Medical Research team lead in the Triple 7 expedition and helped the jumpers prepare physically and mentally also helped them manipulate their sleep schedule for improved performance and stress mitigation and - John Welbourn: John is a former American football offensive tackle and guard and the creator and operator of Power Athlete HQ. This performance-based programming transforms athletic potential into real-world results.
In this episode, we'll be covering papers that were released in January 2023 that target neuronal and synaptic protection in Alzheimer's Disease. If you're interested in the preclinical testing of novel therapeutics and delivery methods, this is the episode for you! Sections in this episode: Novel Therapeutics Targeting Neuroprotection (4:53) Novel Delivery Methods Targeting Neuroprotection (8:49) Targeting Synaptic Pathology (16:42) Targeting BDNF Activation (23:18) We at AMiNDR are eager to hear from you! We opened up a survey available until the end of April for you to tell us what we are doing well, and where we can improve. Access the survey at tinyurl.com/amindrsurvey. All survey responses will be anonymous. By doing the survey, you can choose to enter a draw for a $15USD gift card for any location you choose! -------------------------------------------------------------- To find the numbered bibliography with all the papers covered in this episode, click here, or use the link below:https://drive.google.com/file/d/1-Msw5q_QnkGiEllig2vDXd60BSOzMAnE/view?usp=share_linkTo access the folder with ALL our bibliographies, follow this link (it will be updated as we publish episodes and process bibliographies), or use the link below:https://drive.google.com/drive/folders/1bzSzkY9ZHzzY8Xhzt0HZfZhRG1Gq_Si-?usp=sharingYou can also find all of our bibliographies on our website: amindr.com. -------------------------------------------------------------- Follow-up on social media for more updates!Twitter: @AMiNDR_podcastInstagram: @AMiNDR.podcastFacebook: AMiNDR Youtube: AMiNDR PodcastLinkedIn: AMiNDR PodcastEmail: amindrpodcast@gmail.com -------------------------------------------------------------- Please help us spread the word about AMiNDR to your friends, colleagues, and networks! And if you could leave us a rating and/or review on your streaming app of choice (Apple Podcasts, Spotify, or wherever you listen to the podcast), that would be greatly appreciated! It helps us a lot and we thank you in advance for leaving a review! Don't forget to subscribe to hear about new episodes as they come out too. Thank you to our sponsor, the Canadian Consortium of Neurodegeneration in Aging, or CCNA, for their financial support of this podcast. This helps us to stay on the air and bring you high quality episodes. You can find out more about the CCNA on their website: https://ccna-ccnv.ca/. Our team of volunteers works tirelessly each month to bring you every episode of AMiNDR. This episode was scripted, hosted and edited by Anusha Kamesh, and reviewed by Anelya Gandy. The bibliography and wordcloud were made by Lara Onbasi (www.wordart.com). Big thanks to the sorting team for taking on the enormous task of sorting all of the Alzheimer's Disease papers into episodes each month. For January 2023, the sorters were Elyn Rowe, Christy Yu, Eden Dubchak, Ben Cornish, Kevin Nishimura, Anelya Gandy, Salodin Al-Achkar, and Rob Cloke. Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, Lara Onbasi, Joseph Liang, and Judy Cheng, for keeping everything running smoothly.Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic. https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w -------------------------------------------------------------- If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways. --------------------------------------------------------------*About AMiNDR: * Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"
In this week's episode we will review a study in sub-Saharan Africa where treatment of sickle cell anemia with hydroxyurea is associated with a lower incidence of malaria. New research suggests mild myelosuppression associated with hydroxyurea treatment may actually have a salutary effect. Next, a potential new treatment approach in lower GI acute GVHD. Adding an interleukin-22 therapy to corticosteroid treatment was well tolerated with a high rate of response in this very challenging patient population. Finally, common AML driver mutations such as FLT3ITD (or internal tandem duplications) orchestrate distinct transcriptional and epigenetic programs based on different genetic contexts. In the context of a common pediatric AML mutation, FLT3ITD selectively activated type I interferon signaling, suggesting a distinct therapeutic vulnerability.
Featuring articles on augmenting or switching antidepressants in older adults, lebrikizumab for moderate-to-severe atopic dermatitis, the acute health effects of coffee consumption, Covid-19 staff testing and outcomes in nursing homes, and an mRNA influenza vaccine; a review article on right ventricular failure; a case report of a man with shortness of breath and proteinuria; and Perspective articles on the trials and triumphs of health care antitrust law, on unwinding continuous Medicaid enrollment, and on delirium.
Hillary and Tina cover Henrietta Lacks and Lesley Wegner and Sylvia Gonzalez. Tina's Story Lesley Wenger and Sylvia Gonzales served on the Castle Hills, Texas city council in 2018. BUT when things didn't go their way, they plotted a coup. Hillary's Story Henrietta Lacks contributed to medical science through her illegally harvested immortal cell tissue. BUT when her family finds out, they call for reform and recognition of her contributions. Sources Hillary's Story Brittannica Henrietta Lacks (https://www.britannica.com/biography/Henrietta-Lacks) CNN Estate of Henrietta Lacks sues biotechnical company for nonconsensual use of her cells (https://www.cnn.com/2021/10/05/us/henrietta-lacks-estate-sues-biotech-company/index.html)--by Taylor Romine History Henrietta Lacks: How Her Cells Became One of the Most Important Medical Tools in History (https://www.history.com/news/rebecca-skloot-on-the-immortal-life-of-henrietta-lacks)--by Rebecca Skloot Hopkins Medicine The Legacy of Henrietta Lacks (https://www.hopkinsmedicine.org/henriettalacks/) The Immortal Life of Henrietta Lacks (https://www.hopkinsmedicine.org/henriettalacks/immortal-life-of-henrietta-lacks.html) Nature Henrietta Lacks: science must right a historical wrong (https://www.nature.com/articles/d41586-020-02494-z) The New York Times Henrietta Lacks, Whose Cells Were Taken Without Her Consent, Is Honored by W.H.O (https://www.nytimes.com/2021/10/13/science/henrietta-lacks-cells-who.html).--by Maria Cramer NPR 'Henrietta Lacks': A Donor's Immortal Legacy (https://www.npr.org/2010/02/02/123232331/henrietta-lacks-a-donors-immortal-legacy) Smithsonian Magazine Henrietta Lacks' ‘Immortal' Cells (https://www.smithsonianmag.com/science-nature/henrietta-lacks-immortal-cells-6421299/)--by Sarah Zielinski Wikpedia Henrietta Lacks (https://en.wikipedia.org/wiki/Henrietta_Lacks) Photos Henrietta Lacks (https://static01.nyt.com/images/2013/08/08/science/08zimmer/08zimmer-superJumbo.jpg?quality=75&auto=webp)--from the Henrietta Lacks Foundation via The New York Times HeLa Cells (https://www.nist.gov/sites/default/files/styles/960_x_960_limit/public/images/2022/05/27/shutterstock_336230588.jpg?itok=Zuz6SB6i)--by Heiti Paves/Shutterstock via National Institute of Standard and Technology The Immortal Life of Henrietta Lacks (Novel) (https://upload.wikimedia.org/wikipedia/en/5/5f/The_Immortal_Life_Henrietta_Lacks_%28cover%29.jpg)--book cover by Crown publishers via Wikipedia Tina's Story Forbes Texas Councilwoman Fights Back After Her Opponents Had Her Arrested And Jailed (https://www.forbes.com/sites/instituteforjustice/2020/10/01/texas-councilwoman-fights-back-after-her-opponents-had-her-arrested-and-jailed/?sh=1961bc907fc2)--by Andrew Wimer Fox 29 Castle Hills council member who allegedly plotted against city manager reinstated (https://foxsanantonio.com/castle-hills-council-member-who-allegedly-plotted-against-city-manager-reinstated)--by SBG San Antonio KENS5 Castle Hills city manager fired over confrontations with police, judge (https://www.kens5.com/article/news/local/castle-hills-city-manager-fired-over-confrontations-with-police-judge/273-283516464)--by Dillon Collier KSAT 12 2 Castle Hills council members arrested in alleged plot to oust city manager (https://www.ksat.com/news/2019/07/19/2-castle-hills-council-members-arrested-in-alleged-plot-to-oust-city-manager/)--by Adrian Garcia and Patty Santos Castle Hills City Council votes to fire city manager (https://www.ksat.com/news/2016/07/12/castle-hills-city-council-votes-to-fire-city-manager/)--by Chris Shadrock Petition calls for removal of 2 Castle Hills council members (https://www.ksat.com/news/2019/08/07/petition-calls-for-removal-of-2-castle-hills-council-members/) Questions surround legitimacy of swearing in of Castle Hills City Council member (https://www.ksat.com/news/2019/07/11/questions-surround-legitimacy-of-swearing-in-of-castle-hills-city-council-member/)--by Patty Santos and Jennifer Galvan Tampering charge against former Castle Hills councilwoman dismissed (https://www.ksat.com/news/2019/08/24/tampering-charge-against-former-castle-hills-councilwoman-dismissed/)--by Fares Sabawi and Adrian Garcia News4SA Former Castle Hills councilwoman sues city, claims first amendment rights were violated (https://news4sanantonio.com/news/local/former-castle-hills-councilwoman-sues-city-claims-first-amendment-rights-were-violated)--by Camilla Rambaldi San Antonio Express News Castle Hills council drama gets ‘uglier' (https://www.pressreader.com/usa/san-antonio-express-news/20190829/281569472397204) USA Today City officials threw me in jail to silence me. Years later, I'm still seeking justice (https://www.usatoday.com/story/opinion/voices/2021/10/30/sylvia-gonzalez-qualified-immunity-silence/6104253001/).--by Sylvia Gonzalez Photos Lesley Wenger Mugshot (https://www.ksat.com/news/2019/07/19/2-castle-hills-council-members-arrested-in-alleged-plot-to-oust-city-manager/)--screenshot via KSAT Sylvia Gonzalez Mugshot (https://www.ksat.com/news/2019/07/19/2-castle-hills-council-members-arrested-in-alleged-plot-to-oust-city-manager/)--screenshot via KSAT Ryan Rapelye, Castle Hills City Manager (https://i0.wp.com/sanantonioreport.org/wp-content/uploads/2019/07/CastleHills-CM-Rapeley-7-2019-.jpeg?w=222&ssl=1)--offical photo via San Antonio Report
Learn about the latest medical advancements! Join Dr. Alessio Fasano, director of the Center for Celiac Research and Treatment at Mass General for Children, as he breaks down the research process for medical advancements and what he's doing to combat Celiac disease. Listen now and stay up to date with the latest in medicine! For show notes, visit https://fivejourneys.com/podcasts/medical-research-advancements/ Follow us on Instagram at https://www.instagram.com/fivejourneyspodcast/
Dr. Lattisha Bilbrew is an orthopaedic surgeon specializing in the hand and upper extremities. She joined Resurgens Orthopaedics in 2017. Dr. Bilbrew has been honored with medical accolades such as the Texas Orthopaedic Association Resident Research Award and the Pfizer Award in Excellence and Medical Research. She has also been chosen as one of Modern Luxury's Women of Power & Influence and Influential Atlantans in Medicine. Lattisha was voted as a 40 Under 40 honoree by Georgia Trend.Dr. Bilbrew was born in England and comes from a Jamaican heritage.More from the EntreMD Brand:// COMMUNITY: EntreMD Private Group on FacebookJoin a group of physicians who have decided to build profitable businesses, so they have the freedom to live life and practice medicine on their terms.https://www.facebook.com/groups/entremd// FOLLOWFacebook - https://www.facebook.com/drunachukwuInstagram - https://www.instagram.com/drunachukwuYouTube - https://www.youtube.com/@DrUnachukwuTikTok - https://www.tiktok.com/@dr.unaLinkedIn - www.linkedIn.com/in/druna// WORK WITH MEEntreMD Business School - https://www.entremd.com/business
Featuring articles on inaxaplin in persons with two APOL1 variants, expectant management or early ibuprofen for patent ductus arteriosus, closed-loop control in children with diabetes, BCMA-specific CAR T cells in refractory myeloma; a review article on translation defects in neurodegenerative diseases; a case report of a woman with refractory hemolytic anemia; and Perspective articles on Medicare Part D coverage of antiobesity medications, on the erosion of judicial deference to the FDA, and on pregnancy and residency.
(2:33) - Using Machine Learning to Detect Rare DiseasesThis episode was brought to you by Mouser, our favorite place to get electronics parts for any project, whether it be a hobby at home or a prototype for work. Click HERE to learn about how a) AI is being leveraged in healthcare and b) the tools available from vendors to empower development in this area.
Billions of neurons, all bundled together, control your senses, body, emotions, memory, and more. It's complex and mysterious. Today we're talking with experts who have devoted their lives to understanding what's going on in our heads. Guests include: Dr. Saurav Luthra, sleep medicine specialist; Dr. Gary Gronseth, chair, Department of Neurology, The University of Kansas Medical Center; Dr. Paul Camarata, chair, Department of Neurosurgery, The University of Kansas Medical Center and Dr. Kausik Si, Ph. D., scientific director, Stowers Institute for Medical Research.
Featuring articles on a shorter course for tuberculosis treatment, device-based fever prevention after cardiac arrest, an inhibitor of γ-secretase in desmoid tumors, and the climate gap and the color line; a review article on outcomes after critical illness; a case report of a man with Covid-19, respiratory failure, and rashes; and Perspective articles on diversifying the physician workforce, on electronic prior authorization for prescription drugs, and on when cancer cured pain.