Podcasts about Medical research

Revisited: Guardian journalist Michael Safi looks into the world of artificial intelligence, exploring the dangers and promises it holds for society. Help support our independent journalism at theguardian.com/infocus

Have you heard about the radioactive wolves in Chernobyl? Or the latest gene-editing tech that's curing rare diseases? Or that male birth control might be on the horizon? No?!Well, get ready, because while we've been busy living our lives, genomics has been moving – fast! Things that once read like science fiction are moving on over to the non-fiction section.This season on Nice Genes!, join Dr. Kaylee Byers as she engages in some big genomics breakthroughs – from personalized cancer treatments, to how our bodies react in space, to how animals adapt to the most extreme environments, and whether we can actually change how we age.It's a whole new gene-eration (if you will) of discoveries that you won't want to miss!New episodes every two weeks, starting September 8th. Make sure you follow Nice Genes! so you don't miss an episode!

This week, we feature new research on acute respiratory failure, wheezing in childhood, lung cancer, and obesity. We review myeloproliferative neoplasms and follow a diagnostic case of a patient with myasthenia gravis who developed dyspnea and weakness. Perspectives explore medical marijuana research, AI in clinical care, sexual and gender minority health research, and the Perspectives Editor saying goodbye.

Luke speaks with Associate Professor Justin Boddey from the Walter and Eliza Hall Institute of Medical Research. Listen to Weekend Mornings from 9am, on 2GB Sydney and 4BC BrisbaneSee omnystudio.com/listener for privacy information.

In this week's episode, Blood editor Dr. James Griffin interviews Drs. George Goshua, Gerd Blobel, and Paul Kaminski on their latest articles published in Blood. Dr. Goshua elaborates on the background and then insights from "Haploidentical transplant, gene therapy, and standard care in sickle cell disease: a cost-effectiveness analysis". This analysis provides valuable guidance for clinicians, patients, and health systems as they consider treatment choices. However, as concluded in the accompanying Blood Commentary, the true measure of success is not which therapy “wins” the economic argument, but whether each patient receives the therapy best suited to their clinical needs and values. Then, Drs. Gerd Blobel and Paul Kaminski share "Dissecting polycomb complexes for enhanced fetal hemoglobin production", which utilizes a comprehensive CRISPR-based screen to interrogate the components of these repressive complexes and identified a single protein domain in EZH2, a subunit of PRC2, as a potential therapeutic target. They demonstrate that inhibition of the domain encoded by exon 14 of EZH2 selectively derepresses fetal hemoglobin expression, raising the possibility of developing drugs that specifically target this domain to treat hemoglobinopathies.

This week, we feature new research on polymyalgia rheumatica, hypercholesterolemia, prostate cancer, and multiple myeloma. We review evidence-based strategies for tobacco cessation, and follow a case of a woman with nausea, dizziness, and metabolic acidosis. We discuss recent advances in gene editing for rare metabolic diseases. Perspectives address HIV care, health care quality, medical ethics, and finding resilience in the face of serious illness.

In the second part of their discussion, Sandra and Dr. Lewis focus on the path forward, detailing concrete systemic solutions and policy changes vital for creating safer outcomes for mothers. Dr. Lewis advocates for extending postpartum Medicaid coverage nationwide, stressing that the majority of maternal mortality occurs in the year following delivery — a critical window for intervention. The conversation also covers New York State's vital data-driven research into disparate C-section rates and their associated risks, as well as crucial advice for self-advocacy and the importance of multidisciplinary care and community support. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

Host Sandra Lindsay, DHSc is joined by Dawnette Lewis, MD, MBA, director of Northwell's Center for Maternal Health, to assess the current landscape of maternal morbidity and mortality. Dr. Lewis reveals that the U.S. continues to have one of the highest maternal mortality rates among developed nations, with Black birthing mothers still carrying a disproportionately high burden. She argues that disparities for Black mothers persist even when accounting for varying socioeconomic status, citing historically inequitable care and other systemic barriers that stall progress. The discussion also highlights efforts in New York State to better standardize care and address these complex challenges. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

In this episode of BioTalk with Rich Bendis, Rebecca "Becky" Fisher, PhD, Deputy Director for Program Management at the Congressionally Directed Medical Research Programs, joins the conversation to help listeners better understand one of the federal biomedical research funding pathways that may be less familiar to many entrepreneurs, researchers, and life science companies. Dr. Fisher explains how CDMRP works, how it differs from and complements other federal funders such as NIH and ARPA-H, and why its mission is focused on advancing high-impact research that can lead to cures, improved patient care, breakthrough technologies, and clinical benefit. She also discusses the scale and breadth of CDMRP's portfolio, including its FY26 appropriations of $1.27 billion across 34 program areas and additional targeted topics. A major focus of the conversation is CDMRP's unique approach to consumer involvement. Dr. Fisher explains how patients, caregivers, family members, and others with lived experience help shape program strategy, participate in review, and keep funded research connected to the needs of the communities it is intended to serve. The episode also offers practical guidance for applicants. Dr. Fisher walks through how funding opportunities are developed, where to find open program announcements, how the two-tier review process works, and what makes a strong application stand out. She also shares advice for small businesses, academic investigators, clinicians, translational research teams, and industry partners interested in exploring whether CDMRP may be a fit for their work. Editing and post-production work for this episode was provided by The Podcast Consultant. Dr. Rebecca "Becky" Fisher currently serves as Deputy Director for Program Management at the Congressionally Directed Medical Research Programs within the Defense Health Agency, providing senior-level leadership for the successful administration of Congressional appropriations supporting targeted biomedical research. Dr. Fisher has more than 20 years of experience managing and leading complex biomedical research programs within the Department of War. In her current role, she leads CDMRP staff in developing program strategies, facilitating collaborative efforts, and investing funding to further the CDMRP and DoW biomedical research missions. Her work involves extensive engagement with stakeholders from Congress, government, academia, industry, nonprofit, and consumer advocacy organizations. Dr. Fisher received her PhD in Toxicology from the University of North Carolina at Chapel Hill and completed a Postdoctoral Cancer Research Training Award Fellowship at the National Cancer Institute.

In the second half of their discussion, Dr. Sathya and Dr. Chokshi shift from reflecting on the pandemic to charting a path forward. How do we move from a state of polarization to one of collaboration? Dr. Chokshi details his work with the Common Health Coalition to "dissolve silos" and unite the health sector around common goals. He tackles the critical challenge of proving the ROI of "upstream" preventive care and discusses how technology like AI can finally help bridge the gap between medical breakthroughs and real-world delivery of care. Ending on a powerful note of optimism, Dr. Chokshi shares what gives him hope for the future and why investing in the next generation is the ultimate public health strategy.In the second half of their discussion, Dr. Sathya and former NYC Health Commissioner Dave Chokshi, MD, shift from reflecting on the pandemic to charting a path forward. How do we move from a state of polarization to one of collaboration? Dr. Chokshi details his work with the Common Health Coalition to "dissolve silos" and unite the health sector around common goals. He tackles the critical challenge of proving the ROI of "upstream" preventive care and discusses how technology like AI can finally help bridge the gap between medical breakthroughs and real-world delivery of care. Ending on a powerful note of optimism, Dr. Chokshi shares what gives him hope for the future and why investing in the next generation is the ultimate public health strategy. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

What was it really like to lead New York City's public health response during the darkest days of the Covid-19 pandemic? In the first of a two-part conversation, 20-Minute Health Talk host Chethan Sathya, MD, is joined by friend and colleague, Dave Chokshi, MD, the city's former Health Commissioner. Dr. Chokshi shares his personal story, tracing his path from Louisiana during Hurricane Katrina to the forefront of public health. He provides a candid, behind-the-scenes look at the immense challenges of communicating evolving science in a crisis, the difficulty of balancing public health with economic and personal realities, and the power of everyday heroism that unified the city. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

In this week's episode, Blood editor Dr. Laura Michaelis interviews Drs. Matthew Frank and Jieqing Zhu on their latest articles published in volume 147 issue 22 of Blood. Dr. Frank discusses "How I treat HLH-like toxicities after immune effector cell therapy", in which the two cases presented emphasize the need for early identification, the use of anticytokine therapy with either emapalumab or ruxolitinib when organ toxicities worsen despite conventional CRS-directed treatment, and the need for ancillary supportive care as central to success. Dr. Zhu shares insights from "Structural Basis of HPA-1 a Alloimmunization in FNAIT and Allosteric Regulation of Integrin Conformation" where they probed the structure-function relationships underpinning interactions of alloantibodies against the most common target, human platelet antigen 1a (HPA-1a). Their data can help explain why some alloantibodies cause severe hemorrhagic FNAIT while others result in milder, asymptomatic thrombocytopenia.

This week, we feature new research on chronic kidney disease, high-risk prostate cancer, peripheral artery disease, and oxygen therapy after cardiac arrest. We review the evaluation and management of syncope, follow a challenging case of immune-related inflammatory illness, and report on Perspectives exploring pandemic preparedness, the Bundibugyo Ebola outbreak, and physician mental health.

In the third segment, the conversation turns from metabolic health to scientific culture itself. Kaplan shares the story behind Broken Science, tracing her background in journalism and her interest in nutrition policy, scientific incentives, and how public health narratives are shaped. She discusses concerns about peer review, statistical significance, replication, and the ways scientific certainty can be overstated in medicine and public communication. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

Host Chethan Sathya, MD, welcomes Emily Kaplan, co-founder of Broken Science Initiative and MetFix, a novel approach to fitness and nutrition. Kaplan explains why chronic disease continues to rise even as more Americans go to the gym, arguing that nutrition — not just exercise — is central to better health outcomes. The conversation explores insulin, mitochondrial dysfunction, seed oils, sugar, and the biological mechanisms she believes drive obesity, fatty liver disease, and metabolic illness. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

In part 2 of this 3-part episode, Emily Kaplan describes how MetFix gyms and coaches work alongside physicians to help patients make sustainable lifestyle changes, especially around food, exercise, and metabolic disease. She shares examples of doctors integrating gyms into their practices, using coaches to support patients between annual visits, and creating condition-specific classes for people with type 2 diabetes, menopause-related concerns, and other chronic health issues. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

In this week's episode, Blood editor Dr. Laura Michaelis interviews Drs. Pierre-Yves Dumas and Samik Basu on their latest articles published in Blood. Dr. Dumas talks about "Prognostic impact of FLT3-ITD microclones in young adults with acute myeloid leukemia treated with intensive chemotherapy" where the team was able to identify that ultra-low-burden FLT3-ITD microclones are associated with higher relapse risk and inferior relapse-free survival. Their work encourages the evaluation of FLT3 inhibitor strategies. Dr. Basu discusses "CD19 CAR T-cell therapy is feasible for patients with pemphigus vulgaris treated without lymphodepletion in the RESET-PV trial". In four patients, the treatment was well tolerated and supported CAR T-cell expansion and persistence, challenging the need for lymphodepletion and supporting chemotherapy-free approaches in autoimmune disease.

This week, we feature advances that may change care for prostate cancer, multiple myeloma, acute pain, and IgA nephropathy. We review platelet factor 4 disorders and follow a case of persistent nasal ulceration. Perspectives explore medical aid in dying, federal authority in health care, public health and litigation, and the challenge of delivering life-changing news with honesty and compassion.

More than 155 scientists, physicians and public health advocates are defending Dr. Anthony Fauci ahead of a Senate hearing where Sen. Rand Paul is expected to question the former top U.S. infectious disease expert. The letter accuses the Trump administration and its allies of targeting scientists through political attacks and investigations. Subscribe to our newsletter to stay informed with the latest news from a leading Black-owned & controlled media company: https://aurn.com/newsletter Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Earthworms may be small, limbless, and blind but, as Darwin observed nearly 150 years ago, they play a critical role in soil ecology. Darwin's 19th century insights about the slimy invertebrates are far-reaching, serving as the backbone of modern ecology as a whole. In recent years, scientists are putting their ears to the ground, listening to worms to monitor soil health. Meanwhile, laboratory studies on another kind of worms—flatworms—are providing insights about how memories are stored, and how stem cells self-renew. We get our hands dirty for this episode about the biology and ecology of worms.   Guests:  Philip Ball – science reporter, author of “Beautiful Experiments: An Illustrated History of Experimental Science”   Jacqueline Stroud – soil scientist, University of Warwick, U.K.  Alejandro Sánchez Alvarado  – molecular biologist at the Stowers Institute for Medical Research, whose focus is on stem cells and regeneration  Big Picture Science is part of the Airwave Media podcast network. Please contact advertising@airwavemedia.com to inquire about advertising on Big Picture Science.  You can get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support!  Learn more about your ad choices. Visit megaphone.fm/adchoices

Earthworms may be small, limbless, and blind but, as Darwin observed nearly 150 years ago, they play a critical role in soil ecology. Darwin's 19th century insights about the slimy invertebrates are far-reaching, serving as the backbone of modern ecology as a whole. In recent years, scientists are putting their ears to the ground, listening to worms to monitor soil health. Meanwhile, laboratory studies on another kind of worms—flatworms—are providing insights about how memories are stored, and how stem cells self-renew. We get our hands dirty for this episode about the biology and ecology of worms.   Guests:  Philip Ball – science reporter, author of “Beautiful Experiments: An Illustrated History of Experimental Science”   Jacqueline Stroud – soil scientist, University of Warwick, U.K.  Alejandro Sánchez Alvarado  – molecular biologist at the Stowers Institute for Medical Research, whose focus is on stem cells and regeneration  Big Picture Science is part of the Airwave Media podcast network. Please contact advertising@airwavemedia.com to inquire about advertising on Big Picture Science.  You can get early access to ad-free versions of every episode by joining us on Patreon. Thanks for your support!  Learn more about your ad choices. Visit megaphone.fm/adchoices

What if greatness isn't about the rank you achieve... but the lives you leave behind? In 2004, Brigadier General (Ret.) Dr. Sheila Baxter became the first African American woman in the history of the Army Medical Service Corps to achieve the rank of Brigadier General.But that's not the story that stayed with me. The story that stayed with me was the young basketball player from Franklin, Virginia who simply loved serving people.The lieutenant whose commander challenged her to write a 20-year career plan.The officer who almost left the Army... ...and didn't. The leader who discovered that the higher you rise, the more humble you should become. And the retired general who could have spent retirement anywhere but instead chose to serve unhoused veterans, build affordable housing, and continue changing lives.In this conversation, we talk about:▪️ Why passion matters more than titles▪️ The mentors who changed the course of her life▪️ How to stay humble while leading at the highest levels▪️ What it really feels like to carry the weight of being "the first"▪️ Why she believes Army leadership prepares you for anything in life▪️ The importance of listening before making life-changing decisions▪️ The transition from commanding thousands of Soldiers to serving veterans on the streets of AtlantaOne quote I haven't stopped thinking about:"The higher you go, the more humble you should become."This isn't just an episode for Army leaders.It's for anyone trying to become a better leader, mentor, parent, teammate, or human being.I left this conversation inspired and I think you will too. Sheila R. Baxter is a native of Franklin, Virginia. She was born on 4 April 1955 to the proud parents of (late) John and Mary Baxter. She is one of five children and credits her parents for providing a loving home and family. In 1973, she graduated from Franklin High School. She completed her undergraduate education at Virginia State (now University) in 1977, with a Bachelor of Science degree in Health and Physical Education. She was commissioned as a Second Lieutenant in 1978 after completing the Reserve Officer Training Corps, and she earned recognition as a Distinguished Military Graduate from Virginia State University. She holds a master's degree in health services management from Webster University in St. Louis, Missouri, and a Master of Divinity from the Interdenominational Theological Center (ITC) in Atlanta, Georgia. In May 2024, Baxter completed a Doctor of Ministry degree from the ITC.Her doctoral qualitative research focused on creating access to services for women and men experiencing homelessness in Forest Park, Georgia.     Baxter's military experience began in 1978 as a Second Lieutenant in the Army Medical Service Corps. Throughout her 30 year career, she enjoyed a variety of command and staff assignments including Chief of Staff, Medical Research and Materiel Command, Fort Detrick, Maryland; Logistics Officer for 1st Medical Group, Fort Hood, Texas; Commander, 226th Medical Logistics Battalion in Pirmasens, Germany; Commander, United States Medical Materiel Center, Europe; Deputy Chief of Staff for Logistics for the Army Surgeon General and Commanding General, Madigan Army Medical Center, Fort Lewis, Washington.  In 2004, Baxter became the first African American woman to achieve the rank of Brigadier General in the Army Medical Service Corps. From 2004-2008, she served as Chief of the Medical Service Corps for approximately 9,000 active and Reserve Medical Corps officers. From 2005 to 2008, as Commanding General of Madigan Army Medical Center, she oversaw medical care for more than 40,000 Soldiers and 100,000 beneficiaries across Alaska, California, and Washington. She oversaw a $300 million budget. A screening and health assessment program for returning deployed Soldiers implemented at Madigan during her tenure became a model for the Army.      Brigadier General (Retired) Baxter is a Veteran of the first Gulf War (1990-1991) and has led thousands of Soldiers throughout her 30-year career.      Among her awards, decorations, and badges are the Distinguished Service Medal, Legion of Merit, the Bronze Star, the Meritorious Service Medal with 4 (OLC), the Army Commendation Medal with 2 (OLC), the Army Achievement Medal with 2 (OLC), the Meritorious Unit Commendation, the Army Staff Badge, the Kuwait Liberation Medal, Southwest Asia Service Medal, and the Expert Field Medical Badge.  She is a member of the Military Medical Merit. In July 2002, she received the Honorary Silver Award for excellence in community service from the Lord Mayor of Pirmasens, Germany.In the October 2005 issue of Newsweek magazine, she was recognized as one of the 20 Most Powerful Women in America. In 2009, she became a lifetime member of the National Scholars Honor Society, recognized for her outstanding academic achievements and personal excellence. Baxter's accomplishments as a leader have been highlighted in magazines such as Jet, Ebony, and Charisma. In 2015, she was chosen as one of Virginia's Strong Women in History by the Library of Virginia. From 2011 to 2021, Baxter served as a staff chaplain for unhoused Veterans at the Atlanta VA Healthcare System in Decatur, Georgia. In 2025, Baxter was honored with the Presidential Award for Community Service by President Joe Biden.     She actively serves as a committee member for the Trustee Board of the Interdenominational Theological Center, Atlanta, Georgia. She is an Executive Board member for the National Board for Occupational Therapists. She serves in ministry as a District Missionary, Living Word District COGIC, Forest Park, Georgia under the leadership of Superintendent, Dr. Kenneth Paden. Her hobbies include spending time with family, reading, traveling, watching sports, especially college basketball (March Madness) and Professional Bull Riding. Currently, Baxter continues to assist homeless Veterans and civilians through a non-profit organization called Veterans Haven House. This organization partners to build affordable housing to assist Veterans seeking stability in Clayton County, Georgia. Volunteer with the VA: https://www.va.gov/texas-valley-health-care/work-with-us/volunteer-or-donate/ Disclaimer: The views expressed in this podcast are the guests and host's alone and do not reflect the official position of the Medical Service Corps, the Department of Defense, or the US Government. All information discussed is unclassified approved for public release and found on open cleared sources.For more episodes listen on Apple Podcasts, Spotify, or YouTube @ Be All You Can Be MSC For more information, suggestions, or questions please contact: beallyoucanbemsc@gmail.com

In this week's episode, Blood editor Dr. James Griffin interviews Drs. Hanny Al-Samkari and Xin Zhou on their latest articles published in Blood. This episode highlights two important advances in hematology: the first report from the CHORUS registry for hereditary hemorrhagic telangiectasia (HHT) presented by Dr. Al-Samkari and also the introduction of the ASH Hematomics (ASHOP) platform for integrative genomic data analysis presented by Dr. Zhou. The CHORUS registry reveals that HHT is a progressive, underrecognized inherited bleeding disorder with a substantial burden of recurrent bleeding, iron deficiency, arteriovenous malformations, and life-threatening complications, while emphasizing the need for earlier diagnosis and the development of targeted therapies. The second presentation introduces ASHOP, an open-access platform that enables researchers to explore and integrate large-scale clinical and genomic datasets, facilitating discoveries in leukemia and other hematologic diseases through advanced analytical tools. Together, these studies demonstrate how comprehensive patient registries and innovative data-sharing resources are advancing precision medicine, improving disease understanding, and accelerating future research across hematology.

This week, we bring you advances in pancreatic and bladder cancer, preventing gonorrhea, a promising new therapy for adolescent hypertrophic cardiomyopathy, and a review of antiretroviral treatment for HIV. We also follow a striking case of vision loss that led to an unexpected diagnosis and discuss Perspectives on vaccine evidence, hepatitis C elimination, the endorsements of prescription drugs on social media, and the enduring intersection of love and loss in medicine.

20 Minute Health Talk host Chethan Sathya, MD, welcomes Dr. Jackie Gerhart, Chief Medical Officer of the health technology giant Epic Systems. Dr. Gerhart shares her unconventional journey from a small-town family physician with a background in engineering to a leader at one of the world's most influential EMR companies. The conversation delves into the critical topic of change management, exploring the keys to helping clinicians adopt new tools and how data can prove the value of evolving workflows. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

In part 2, the discussion shifts to the future, as Dr. Gerhart outlines Epic's vision for the broader health tech ecosystem and its philosophy on integrating with partners. Discover how the role of EHR is evolving into the future of care, powered by data from wearables, community sources, and real-world evidence. A key focus is the transformative power of AI and large medical models (LMMs), which aim to predict the "next medical event" and accelerate diagnoses and cures. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

Dawn A. Marcus is a board-certified neurologist, medical researcher, and author whose work explores the remarkable connection between human health and companion animals. In The Power of Wagging Tails, Dr. Marcus examines how dogs can positively influence physical, emotional, and mental well-being. Drawing on scientific research and real-life experiences, she discusses the many ways canine companionship may help reduce stress, encourage physical activity, improve social connections, and enhance overall quality of life. Blending medical expertise with a deep appreciation for the human-animal bond, Dr. Marcus highlights the growing body of evidence supporting the therapeutic benefits of pets in healthcare and everyday life. From lowering blood pressure and easing anxiety to providing comfort during illness and recovery, The Power of Wagging Tails celebrates the unique relationship between people and their dogs while offering practical insights into how these loyal companions can contribute to healthier, happier lives.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-x-zone-radio-tv-show--1078348/support.Please note that all CANCOM/XZBN radio and/or television shows are Copyright © REL-MAR McConnell Meda Company, Niagara, Ontario, Canada – www.rel-mar.com. For more Episodes of this show and all shows produced, broadcasted and syndicated from REL-MAR McConell Media Company and The 'X' Zone Broadcast Network and the 'X' Zone TV Channell, visit www.xzbn.net. For programming, distribution, and syndication inquiries, email programming@xzbn.net.We are proud to announce the we have launched TWATNews.com, launched in August 2025.TWATNews.com is an independent online news platform dedicated to uncovering the truth about Donald Trump and his ongoing influence in politics, business, and society. Unlike mainstream outlets that often sanitize, soften, or ignore stories that challenge Trump and his allies, TWATNews digs deeper to deliver hard-hitting articles, investigative features, and sharp commentary that mainstream media won't touch.These are stories and articles that you will not read anywhere else.Our mission is simple: to expose corruption, lies, and authoritarian tendencies while giving voice to the perspectives and evidence that are often marginalized or buried by corporate-controlled media

Disclaimer: The views expressed by my guest are their own. This interview is for informational and educational purposes only and should not be considered medical advice. Please do your own research and consult a qualified healthcare professional before making medical decisions.Cancer has long been viewed through the lens of genetics, but what if one of the most widely accepted theories is missing a much bigger piece of the puzzle?In this conversation, researcher and author David Rasnick shares why he believes chromosomal imbalance—not gene mutations—is the driving force behind cancer.We discuss the work of Theodor Boveri, why this theory has remained outside the medical mainstream, the role of spontaneous remission, fever therapy, Coley's toxins, glycolysis, and the Warburg Effect, as well as why David believes understanding how cancer develops over time is critical to finding better approaches.David also discusses why many conventional cancer treatments appear to work initially before cancer returns, and explains his perspective on the body's natural ability to recognize and eliminate abnormal cells. Throughout our conversation, he challenges long-held assumptions and encourages listeners to examine the scientific literature for themselves.This Ke Ala Side version includes the portions that were edited or muted from the public YouTube release. If you'd like to hear the complete extended interview with additional discussion, it's available on The Plus Side.Learn more about David Rasnick: https://davidrasnick.comBUY A COFFEE LINK Support the Show & Stay Connected:Buy Me a Coffee: https://buymeacoffee.com/sensiblehippieJoin My Patreon for ad-free episodes & exclusive content:https://Patreon.com/WakeupwithMiyaIf you're joining Waiola – The Plus Side, please subscribe through a web browser (Safari or Chrome) instead of the Patreon app — it directly supports the show.Mahalo nui loa for supporting independent work and helping keep this platform growing.Shop my Amazon Storefront: https://www.amazon.com/shop/profile/amzn1.account.AGYOPCXXGH6MN5RVAKGQWVZUZLEA/list/26B87RB4FZ9W2?ref_=cm_sw_r_cp_ud_aipsflist_6BWRT43TH4MY2NM2XD6XWant to be on the show or suggest a guest? I'm looking for guests who can speak on human trafficking, the paranormal, occult symbolism, hidden history, spiritual warfare, ancient mysteries, and specific military stories involving covert operations, secret programs, psychological warfare, unexplained events, and firsthand accounts.Email me at: Miya@wakeupwithmiya.comFollow Me Online:Instagram: https://www.instagram.com/WakeupwithMiyaFacebook: https://www.facebook.com/WakeupwithMiyaExclusive Discount!Shop at LVNTA:https://lvnta.com/lv_IcTq5EmoFKaZfJhTiSUse code OHANA for 20% off!Listen on Your Favorite Platform: Spotify, Apple Podcasts, YouTube, and everywhere podcasts are available!RATE & REVIEW: Apple: https://podcasts.apple.com/us/podcast/wake-up-with-miya/id1627169850 Spotify: https://open.spotify.com/show/0UYrXCgma1lJYzf8glnAxyMusic Credits:Beginning: "Echoes in the Shadows" - DKEnd Music: “Crazy” - EkoBecome a supporter of this podcast: https://www.spreaker.com/podcast/wake-up-with-miya--6339129/support.

On episode 251 of The Compound and Friends, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Downtown Josh Brown⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and Sean Russo are joined by Jonathan Thomas, CEO of American Century Investments, to discuss: the remarkable rise of Avantis Investors, why active ETFs are gaining ground, what it takes to build investment products that can outperform without taking excessive risk, whether AI is creating an earnings bubble, why the market is broadening beyond the Magnificent Seven, and where the biggest long-term opportunities in AI may emerge. Plus, Jonathan shares the story behind American Century's ownership structure, which has directed billions of dollars toward cancer and genetic-disease research at the Stowers Institute for Medical Research—and takes us inside one of the most exclusive celebrity weddings imaginable. This episode is sponsored by Public and Vanguard. Visit https://public.com/compound to learn more. To learn more about Vanguard bonds, visit https://vanguard.com/audio Sign up for The Compound Newsletter and never miss out: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠thecompoundnews.com/subscribe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠instagram.com/thecompoundnews⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠twitter.com/thecompoundnews⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠linkedin.com/company/the-compound-media/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠tiktok.com/@thecompoundnews⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Investing involves the risk of loss. This podcast is for informational purposes only and should not be or regarded as personalized investment advice or relied upon for investment decisions. Michael Batnick and Josh Brown are employees of Ritholtz Wealth Management and may maintain positions in the securities discussed in this video. All opinions expressed by them are solely their own opinion and do not reflect the opinion of Ritholtz Wealth Management. The Compound Media, Incorporated, an affiliate of ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Ritholtz Wealth Management⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, receives payment from various entities for advertisements in affiliated podcasts, blogs and emails. Inclusion of such advertisements does not constitute or imply endorsement, sponsorship or recommendation thereof, or any affiliation therewith, by the Content Creator or by Ritholtz Wealth Management or any of its employees. For additional advertisement disclaimers see here ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ritholtzwealth.com/advertising-disclaimers⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Investments in securities involve the risk of loss. Any mention of a particular security and related performance data is not a recommendation to buy or sell that security. The information provided on this website (including any information that may be accessed through this website) is not directed at any investor or category of investors and is provided solely as general information. Obviously nothing on this channel should be considered as personalized financial advice or a solicitation to buy or sell any securities. See our disclosures here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ritholtzwealth.com/podcast-youtube-disclosures/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Public Disclosure: Paid for by Public Investing. Brokerage services by Open to the Public Investing Inc, member FINRA & SIPC. Advisory services by Public Advisors LLC, SEC-registered adviser. Complete disclosures available at https://public.com/disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this week's episode, Blood editor Dr. James Griffin interviews Drs. Haris Sohail and Lucas Kühne on their latest articles published in volume 147 issue 21 of Blood. In this CME article titled, "Retrospective, Real-World Study of IV Iron Use to Treat Iron deficiency Anemia During Acute Infection",  Sohail et al show that IV iron given during acute infection with iron deficiency anemia is associated with improved 14-day and 90-day survival as well as hemoglobin recovery. Although this report has the limitations of a retrospective study, these findings challenge current practice and support randomized trials that include patients with infection. In "Revisiting Clinical Response and Refractoriness in Immune Thrombotic Thrombocytopenic Purpura", Kühne et al show in a multicenter registry study of 204 patients that refractoriness during caplacizumab treatment in immune TTP is uncommon and, when observed, is typically associated with confounding clinical factors. These findings underscore the importance of careful clinical reassessment and evaluation for alternative etiologies in patients with delayed platelet recovery, rather than attributing such cases to true treatment resistance.

What begins as a medical research assignment quickly turns into a murder investigation.On this episode of This Week in America with Ric Bratton, author Susann Camus discusses her gripping new novel, Bless Your Heart: A Jeannie Johal Thriller, a fast-paced mystery filled with pharmaceutical intrigue, Southern charm, and unexpected twists.Healthcare researcher Jeannie Johal arrives in Greenville, North Carolina, to investigate suspicious activity surrounding a promising new drug study. Before she can even begin, her new boss is murdered. Suddenly, Jeannie finds herself navigating a maze of hidden motives, dangerous secrets, poisonous plants, and a community where everyone seems to know more than they're willing to admit.With authentic medical details, memorable characters, and suspense that keeps readers guessing until the final pages, Bless Your Heart is a thriller that mystery lovers won't want to miss.If you enjoy authors like Michael Connelly, Lisa Gardner, Karin Slaughter, or Jeffrey Deaver, this conversation is for you.This Week in America with Ric Bratton is one of America's premier syndicated radio shows and podcasts, featuring engaging conversations with bestselling authors, business leaders, health experts, historians, innovators, and thought leaders. Heard on more than 100 radio stations and podcast platforms worldwide, each episode delivers practical advice, inspiring stories, expert insights, and thought-provoking discussions covering business, personal development, health, wellness, technology, history, education, entertainment, and the issues that matter most.Whether you're a fan of medical thrillers, crime fiction, murder mysteries, suspense novels, strong female protagonists, pharmaceutical conspiracies, Southern mysteries, or compelling page-turners, Ric Bratton's conversation with Susann Camus offers an inside look at the inspiration behind Bless Your Heart and the creative process of building an unforgettable thriller. Don't miss this exciting episode of This Week in America.https://www.amazon.com/Bless-Your-Heart-Jeannie-Thrillers/dp/B0GNP4Q9J5/ref=tmm_aud_swatch_0https://www.susanncamus.com/https://christianworksmedia.com/http://www.bluefunkbroadcasting.com/root/twia/71626scam.mp3  Keywords Susann Camus, Bless Your Heart, Jeannie Johal, Jeannie Johal Thriller, medical thriller, murder mystery, crime fiction, suspense thriller, pharmaceutical conspiracy, healthcare thriller, mystery novel, Southern mystery, Greenville North Carolina, Pitt County Arboretum, master gardener, women sleuths, female detective, hospital thriller, epidemiology, healthcare research, public health, suspense novels, page turner, mystery podcast, author interview, thriller books, crime novels, book podcast, Ric Bratton, This Week in America, bestselling thrillers, medical suspense, women in fiction, investigative thriller

This week, we present advances in the treatment of multiple myeloma, systemic lupus erythematosus, and coronary artery disease, alongside new national data on health care–associated infections. We also review fibromyalgia and the emerging Bundibugyo virus outbreak, follow a surprising diagnostic case of alpha-gal syndrome, and explore Perspectives on caring for vulnerable patients, trustworthy health information, pharmacotherapeutic decisions in autism care, and the experience of caring for a parent with dementia.

Joining host Chethan Sathya, MD, are the three authors of Information Sick — Joanne Kenen, Joshua Sharfstein, MD and Lymari Morales — for a candid look at the erosion of trust in public health. Pointing to the collapse of local newsrooms, the rise of social media echo chambers, and the pressures of an election-year crisis, they reflect on how crisis communication moved from a single authoritative voice to a fragmented landscape where headlines overstate certainty, public health is underfunded, and leaders face threats.  Disclaimer: The opinions expressed herein are those of the participants and do not necessarily reflect the views of The Johns Hopkins University. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

In part 2, the group pivots to solutions, discussing how to distinguish “trusted” from “credible” sources, exploring ways to find common ground across divides without endorsing harmful claims, and underscoring how shifting official guidance and muddled signals complicate the moment. The takeaway: focus on in‑person engagement, credible messengers, and policies built in draft with public input—plus a note of optimism that shared goals for healthy families and communities can anchor the path forward. Disclaimer: The opinions expressed herein are those of the participants and do not necessarily reflect the views of The Johns Hopkins University. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

In this episode, we sit down with Professor Jay Horvat from the University of Newcastle and the Hunter Medical Research Institute (HMRI) to discuss why lung health is fundamental to overall wellbeing and how emerging research is uncovering surprising new influences on respiratory disease. Professor Horvat explains the challenges faced by Australians living with asthma, chronic obstructive pulmonary disease (COPD), and particularly those managing both conditions at the same time. We explore groundbreaking research investigating how the body's metabolism - including factors such as blood sugar levels, cholesterol and excess abdominal fat - may contribute to lung inflammation and breathing difficulties. Professor Horvat discusses how a better understanding of these connections could lead to new treatments, lifestyle interventions and improved outcomes for people with chronic respiratory disease.See omnystudio.com/listener for privacy information.

In this week's episode, Blood editor Dr. Laura Michaelis interviews Drs. Kirsty Hillier and Marco Ruella on their latest articles published in Blood. For "Predicting Development of Pediatric Chronic Immune Thrombocytopenia at Disease Onset Using a Statistical Risk Model", Dr. Hillier shares the potential benefits of incorporating this new model to enhance the care of the 1 in 4 patients who develop chronic ITP. As an alternative to current guidelines which advise providers to "wait and see", this online model determines patients who are at risk for chronic ITP, allowing for providers to make informed decisions on their continued care. In "Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies", Dr. Ruella explains how the treatment of T-cell neoplasms is limited by a lack of discriminating T-cell antigens that allow for effective antitumor responses while preventing CAR T-cell fratricide. The team found that CD2 was a viable target, especially combined with a novel PD-1:CD2 switch receptor to remedy dysfunction caused by CD2 deletion.  

This week, we present advances in the treatment of idiopathic pulmonary fibrosis, hypothalamic obesity, and lung cancer. We review nutrition in critical illness and follow a diagnostic case involving a patient who had a lung transplant. The Editors warn about the politicization of science. We discuss the dead donor rule in an era of voluntary euthanasia. Perspectives explore the forthcoming crisis in long-term care, reproductive medicine, and the realities of caring for loved ones at the end of life.

Send us Fan MailThere are very few cures for cancers that have already spread. So what does a good outcome actually look like?In this clip from our episode “How Targeted Radiotherapy Is Changing Cancer Care”, host David E. Williams and John Babich, Founder, President, and Chief Scientific Officer of Ratio Therapeutics, break down what extending life with quality really means in cancer care, and why giving someone eight more months where they can still live their life is the philosophy driving the work at Ratio Therapeutics.Listen to the full episode here

Dr. Sathya dives into Dr. Pearl's book, ChatGPT, MD, leading to a candid, forward-looking discussion about generative AI's potential to make care continuous — not episodic — especially in chronic disease management. They explore Utah's move to allow AI to monitor chronic conditions and renew meds, and why clinician-led adoption is essential. Dr. Pearl discusses training LLMs on real-world health system data and the implications for primary and specialty care capacity.  Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

Host Chethan Sathya, MD, sits down with Robert Pearl, MD — Stanford professor, former CEO of Kaiser Permanente, and author of ChatGPT, MD — to trace his journey from Long Island roots and cleft lip/palate missions to leading one of the nation's largest integrated health systems. Dr. Pearl shares his unexpected pivot from the operating room to administration, and what it was like to step into a leadership role during a financial crisis. This conversation sets the case for integrated, capitated care and explores why technology only transforms healthcare when it's coupled with operational excellence. Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn.

Send us Fan MailFor decades, cancer treatment has rested on three pillars: surgery, chemotherapy, and external beam radiation. A fourth is now taking shape, and it is drawing billions in investment from some of the largest pharmaceutical companies in the world.John Babich, Founder, President, and Chief Scientific Officer of Ratio Therapeutics, joins host David E. Williams to explain how targeted radiotherapeutics pair a tumor-seeking molecule with a radioactive payload, delivering radiation to cancer cells while sparing healthy tissue. He also unpacks what Pluvicto's success in prostate cancer signals for the future of radioligand therapy.

Researchers claim they are closer to creating life from nothing after building tiny, quivering blobs that use lab-made DNA to feed, grow and multiply in a dish. To find out how significant this step is, and where scientists hope it will lead, Madeleine Finlay hears from co-host Ian Sample and from Kate Adamala, professor of genetics at the University of Minnesota. Help support our independent journalism at theguardian.com/sciencepod

In this week's episode, Blood editor Dr. James Griffin interviews Drs. Heinz Zoller and Raul Ribeiro on their latest articles published in Blood. Dr. Zoller discusses "Ferric Carboxymaltose Increases Fracture Risk in Patients and Reduces Bone Formation in Mice with Iron Deficiency Anemia", and how these findings support consideration of alternative IV iron formulations that provide similar efficacy without risk of skeletal complications.  Dr. Ribeiro discusses "A low-versus standard-dose regimen an induction for AML: a multicenter, randomized noninferiority trial" and how the low-dose regimen is associated with fewer toxicities, faster hematologic recovery, and reduced health care costs, suggesting a feasible treatment strategy for resource-limited settings.

This week, we discuss less-invasive approaches to guiding coronary intervention, new strategies for preventing kidney cancer recurrence, and head-to-head treatment data in multiple sclerosis. We review advances in multiple sclerosis, follow a diagnostic journey involving gait instability, and discuss correcting false narratives. Perspectives examine physicians and the body politic, chronic pain and OUD, and the often-overlooked burden of cognitive symptoms.

Send us Fan MailThe COVID-19 pandemic proved vaccine platforms can move at unprecedented speed. It also revealed how dangerously narrow the world's response really was, built almost entirely on a single technology.Dr. Dan Barouch and Kris Brown, Co-Founders of Vector Sciences, join host David E. Williams to discuss why durable pandemic preparedness depends on having multiple vaccine platforms rather than just one, how their Rheovax platform uses mucosal immunity delivered through the nose to block transmission rather than just prevent severe disease, and why public trust in vaccines depends on being honest about what each technology can and cannot actually do.

This week, we discuss a promising step toward a functional cure for chronic hepatitis B, first-line pulsed field ablation for persistent atrial fibrillation, reducing the demand for transfusion in surgery, treatment for rifampicin-resistant tuberculosis, and a decade-long look at CAR T-cell therapy outcomes. We review peanut allergy and discuss a case of a man with leg weakness, pain, and weight loss; Perspectives explore GLP-1 access, air-quality policy, and the human realities of homelessness.

Send us Fan MailGLP-1 drugs were designed for weight loss. Now they may be showing up in cancer research in a way nobody expected.In this clip from our episode “The Business & Science Behind the GLP-1 Boom”, hosts David E. Williams and John Driscoll break down what the 2026 ASCO annual meeting revealed about GLP-1s and their potential to reduce cancer progression in lung, breast, colorectal, and liver cancer.Listen to the full episode here

This week, we discuss endovascular therapy for post-thrombotic syndrome, new evidence on prehospital blood transfusion strategies in trauma patients, and a trial of cefazolin for Staph. aureus bacteremia. We examine evolving approaches to thyroid cancer and share a case of a man with pancytopenia after heart transplantation. Perspectives explore psychedelic therapy, the convergence of Down syndrome and Alzheimer's disease, and treating addiction.

A daily pill can double survival time in patients with the world's deadliest cancer, according to the results of a clinical trial that experts are saying is a gamechanger and one of the biggest breakthroughs in decades. To find out more about how daraxonrasib works and how life-changing it could be for patients, Madeleine Finlay speaks to Prof Naureen Starling, consultant medical oncologist at the Royal Marsden hospital. Help support our independent journalism at theguardian.com/sciencepod

We recently got a call from a SciFri listener in Florida who has autoimmune arthritis. He told us that over the years he'd taken 10 drugs, and each out eventually stopped working. He then tried to enroll in a clinical trial for a new drug for his condition, but he was rejected specifically because he was on his 10th drug. Today we're digging into clinical trials and how they work. Are there incentives for drug developers to leave out “problem children”? Or is it more complicated than that? Flora talks with lawyer and bioethicist Holly Fernandez Lynch about what clinical trials are designed to do, how participants are chosen, and where FDA regulation comes into play. Guest: Dr. Holly Fernandez Lynch is an associate professor of medical ethics and health policy at the University of Pennsylvania. Other episodes you may enjoy: Why so many studies can't be replicatedCan ‘Suggestion-Box Science' Make Public Health More Useful? Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-4-SCIFRI Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.