Podcasts about Medical research

In this week's episode of the Blood podcast, editor Dr. James Griffin interviews Drs. Christian Gorzelanny and Rebecca Leaf on their latest articles published in this week's issue of Blood. Dr. Gorzelanny discusses compelling evidence for a new mechanism that amplifies their proinflammatory actions in "Lipid nanotubes unmask neutrophils for complement attack", demonstrating the pathological role of this process in a range of inflammatory disorders in order to stimulate intense study of how to regulate nanotube formation for therapeutic benefit. In "Immune thrombocytopenia in patients treated with immune checkpoint inhibitors" Dr. Leaf and colleagues define the incidence, clinical features, and outcomes of ICI-induced immune thrombocytopenia. Showing that ICI-induced immune thrombocytopenia is associated with excess mortality, these data should provide an impetus to greater recognition and to protocolization of effective interventions.

Grey-market injectable peptides – a category of substances with obscure, alphanumeric names such as BPC-157, GHK-Cu, or TB-500 – have developed a devoted following among biohackers and health optimisers. To understand how these unregulated substances have become mainstream and what they could be doing in our bodies, Madeleine Finlay hears from journalist Adrienne Matei and from Dr Anna Barnard, an associate professor at Imperial College London who researches peptides. Help support our independent journalism at theguardian.com/sciencepod

Robotic pets make life easier for patients with dementia; Risks, benefits of “natural” ED formulas; Sorting out those pricey new injectable osteoporosis drugs; Daily multivitamin delays biological aging; Study challenges notion that aging means inevitable decline; Breastfeeding confers weight loss benefits—to moms; Can you avoid a colonoscopy with a new colon cancer blood test? Color blindness may hide warning signs of cancer.

Epidemiologist Yvonne “Bonnie” Maldonado is an expert in vaccine research and public health. Look back centuries, and the story is always the same, she says: Death rates from viruses have plummeted, especially in children and the elderly. And yet, millions of children die each year from vaccine-preventable diseases. Vaccines need a return of public confidence, and that starts with better messaging and greater support of nongovernmental messengers like herself. The bottom line is that vaccines are safe, she says. Vaccines work and we have saved many lives because of them, Maldonado reminds host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu. Episode Reference Links: Stanford Profile: Yvonne Maldonado Connect With Us: Episode Transcripts >>> The Future of Everything Website Connect with Russ >>> Threads / Bluesky / Mastodon Connect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook Chapters: (00:00:00) Introduction Russ Altman introduces guest Yvonne “Bonnie” Maldonado, a professor of pediatrics, epidemiology and population health at Stanford University. (00:03:01) Career in Vaccines Bonnie shares what led to her career in vaccine research. (00:04:53) How Vaccines Work How vaccines train the immune system to recognize and fight pathogens. (00:06:46) Why Vaccine Responses Vary The variability in immune responses and breakthrough infections. (00:09:22) Risk vs. Benefit in Vaccines How researchers evaluate side effects versus disease severity. (00:11:53) How Viruses Evolve The evolutionary dynamics that shape viral behavior. (00:13:59) Vaccine Boosters Why some vaccines last for life while others require multiple doses. (00:17:14) Herd Immunity How community protection works and why vaccination rates matter. (00:21:22) Vaccine Controversy The controversy surrounding vaccines and what led to it. (00:24:27) Global Vaccine Hesitancy How declining trust and past outbreaks influence vaccination globally. (00:27:07) The Future of Vaccines Why vaccines are essential and how outbreaks shape public response. (00:29:08) Preparing for Future Pandemics How healthcare systems prepare for new threats after COVID-19. (00:30:43) Future In a Minute Rapid-fire Q&A: hope, public trust, and the future of health. (00:32:54) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this week's episode, Blood editor Dr. Laura Michaelis interviews authors Drs. Marion Falabrègue and Ajai Chari on their papers published in volume 146 issue 24 of Blood. The work of Dr. Falabrègue and colleagues in "Intestinal hepcidin overexpression promotes iron deficiency anemia and counteracts iron overload via DMT1 downregulation" indicates that iron absorption from the apical surface of enterocytes can be modulated through manipulation of the hepcidin-DMT1 interaction, opening new avenues for research and therapeutic manipulation. "Talquetamab plus daratumumab in multiple myeloma" features a phase 1b/2 trial of 65 heavily pretreated patients with MM, where Chari et al combined daratumumab and talquetamab, a GPRC5D-targeting bispecific antibody, reporting depletion of CD38-expressing regulatory T cells following daratumumab and impressive efficacy, with an 80% overall (57% complete) response rate and median progression-free survival of 23.3 months. This regimen is now being evaluated in a phase 3 trial. 

On social media, the vagus nerve often gets billed as the gateway to nervous system nirvana: It's your ticket to better rest, relaxation, and health if you “stimulate” it correctly. Where did this idea come from, and what does the research say?  Host Flora Lichtman talks with neurosurgeon Kevin Tracey, a pioneer of a field called bioelectronic medicine, which uses techniques to stimulate the nervous system with electricity. Back in the 1990s, he was the first to discover that the vagus nerve regulates the immune system and inflammation. Guest: Dr. Kevin Tracey is a neurosurgeon, and president and CEO of the Feinstein Institutes for Medical Research at Northwell Health. He is the author of The Great Nerve. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

This week, we explore new evidence comparing oral anticoagulants for acute venous thromboembolism, treatment for chemotherapy-induced thrombocytopenia, and early results of gene therapy for inherited deafness. We also examine evolving strategies for chronic lymphocytic leukemia, review the management of polymyalgia rheumatica, and present a case discussion of a woman with chest pain, dyspnea, and syncope. We explore gastric cancer prevention, competency-based billing, the health consequences of immigration enforcement, access to high-cost gene therapies, and we present a Perspective on good compressions.

In part two of this discussion with Tara Narula, MD, cardiologist at Lenox Hill Hospital and ABC News Chief Medical Correspondent, she explains to 20-Minute Health Talk host Sandra Lindsay the steps for building resilience to handle difficult events and reduce stress overall. Using patient stories and her personal experiences, Dr. Narula lays out actionable strategies for building resilience through acceptance, flexible thinking, social connection, and purpose. This is Part 2 of this series. Listen to Part 1 About Northwell Health Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch more episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

Join 20-Minute Health Talk host Sandra Lindsay in conversation with renowned cardiologist and ABC News Chief Medical Correspondent Tara Narula, MD, as she discusses her groundbreaking book, "The Healing Power of Resilience." Discover how emotional and physical health intersect, why resilience is both innate and learnable, and practical tools for bouncing forward—not just bouncing back—from life's challenges. Dr. Narula reveals how resilience came to play such a large role in both her treatment of patients and in her own life. This is Part 1 of this series. Listen to Part 2 About Northwell Health Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch more episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

John Maytham is joined by Nosiphiwo Nzimande, a researcher with the South African Medical Research Council and the Wits Centre for Health Economics and Decision Science – Priceless SA, who argues that South Africa urgently needs child-centric advertising regulation that prioritises public health and children’s rights in shared public spaces. Afternoon Drive with John Maytham is the late afternoon show on CapeTalk. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30 pm. CapeTalk fans call in to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 to 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show, go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

Dismal prediction that, by 2050, 60% of women will suffer from cardiovascular disease; Yes, it's true that childhood and adolescent obesity, once rare, is now soaring; Treatments for osteopenia; Dentists continue to write prescriptions for potentially deadly antibiotic; A man, in love with his Chatbot, commits suicide to join her in the virtual world; Olive oil is calorie dense—but its consumption results in weight loss; Can “bio-regulator peptides” stave off kidney failure?

Medical researchers say New Zealanders are missing out on a transformative cancer treatment that's been proven to make a difference. It's called CAR T-cell therapy. As it stands, Kiwis have to travel thousands of kilometres overseas to receive this treament, which in and of itself is complex and costly. The Malaghan Institute of Medical Research is spearheading an awareness campaign about CAR T-cell therapy this month, and clinical director Professor Robert Weinkove joins me now to discuss it.

In this episode, Niall speaks with Dr. Kevin Tracey, a neurosurgeon, inventor, researcher, and author of “The Great Nerve”, who leads the Feinstein Institutes for Medical Research. Dr. Tracey's research has shown how the vagus nerve connects the brain and immune system, controlling inflammation in the body. His work has led to FDA-approved treatments for rheumatoid arthritis and may help with depression, PTSD, and other inflammatory conditions. In this conversation, they explore: — How the vagus nerve acts as a biological “brake” for inflammation — The potential of bioelectronic medicine to treat inflammatory diseases without immunosuppression — The story of Kelly Owens, whose life was transformed by vagus nerve stimulation — Why inflammation may underlie many modern diseases — The future of precision medicine using targeted nerve stimulation And more. You can learn more about Dr. Tracey's work through his book “The Great Nerve”, or at X at x.com/KevinJTraceyMD. — Kevin J. Tracey is president and CEO of, and the Karches Family Distinguished Chair in Medical Research at the Feinstein Institutes for Medical Research; professor of Molecular Medicine and Neurosurgery at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell; and Executive Vice President, Research, at Northwell Health. A leader in the scientific fields of inflammation and bioelectronic medicine, his contributions include discovery and molecular mapping of neural circuits controlling immunity. Dr. Tracey received his BS in chemistry, summa cum laude, Phi Beta Kappa, from Boston College in 1979, and his MD from Boston University in 1983. He trained in neurosurgery from 1983 to 1992 at the New York Hospital-Cornell University Medical Center and was a guest investigator at the Rockefeller University before moving in 1992 to the Feinstein Institutes. There he directs the Laboratory of Biomedical Science and was appointed president and CEO in 2005. An inventor of more than 120 United States patents and author of more than 400 scientific publications, he cofounded the Global Sepsis Alliance, a non-profit organization supporting the efforts of more than 1 million sepsis caregivers in over 70 countries. Dr. Tracey is the author of Fatal Sequence (Dana Press) and delivers lectures nationally and internationally on inflammation, sepsis, the neuroscience of immunity, and bioelectronic medicine. --- Interview Link: — Dr. Tracey's X: http://x.com/KevinJTraceyMD

In this week's episode, Blood associate editor Dr. Laura Michaelis interviews Drs. Mark Sorial and Emmanuelle Passegue on their articles published in volume 147 issue 7 of Blood. Dr. Sorial discusses "Early time to relapse as a survival prognosticator in nodal mature T-cell lymphomas: results from the PETAL consortium" where he and his team evaluated the prognostic significance of early relapse in a large retrospective cohort. They report a time to relapse of

This week, we explore a phase 3 trial of finerenone in type 1 diabetes and chronic kidney disease and guidance on timing of nonculprit-lesion PCI after STEMI. We cover an investigational therapy for Dravet syndrome and neoadjuvant treatment for high-risk intrahepatic cholangiocarcinoma. We review the effects of radiotherapy on normal tissue, a puzzling case of progressive neurologic decline after suspected foodborne illness, and Perspectives on private equity, the AHEAD model, and medical credit cards.

In part 2 of this 20-Minute Health Talk podcast, host Chethan Sathya, MD, and guest Chelsea Clinton discuss how to convert hope into action. Their conversation shifts to the future, exploring what it takes to cultivate the next generation of leaders in a world facing immense challenges. She details her work with the Clinton Global Initiative, a platform that empowers young people with the tools to create tangible change. While warning of the threat posed by misinformation, Clinton shares her perspective as a mother on what fuels her drive. Ultimately, she argues for active engagement and the profound responsibility we all have to inspire and build a more optimistic, equitable future. This is Part 2 of this series. Listen to Part 1 About Northwell Health Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch more episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

How do you solve problems as complex as drug pricing or childhood obesity? Chelsea Clinton, vice chair of the Clinton Foundation, pulls back the curtain on data-driven methodology. She and host Chethan Sathya, MD, discuss how the foundation moves beyond good intentions, relying on hard evidence and measurable outcomes to prove impact. Central to this strategy is forging public-private partnerships — even with "unlikely allies" such as major corporations — to create systemic change. Clinton explains why pragmatism and rigorous analysis are essential tools for tackling the world's most pressing health challenges, ensuring that every initiative is both sustainable and effective. This is Part 1 of this series. Listen to Part 2 About Northwell Health Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch more episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

The average British household usually puts on their central heating by October 24, according to British Gas. But this year, thanks to soaring energy costs, and a mild winter it may well be later. Turning down your heating can have real savings. The Energy Saving Trust calculates that turning your thermostat down from 20c to 19c should cut your energy bill by around 10 per cent. But as well as saving money there are possible health benefits. According to a study carried out by the Garvan Institute of Medical Research in Australia spending time in an environment at 19° increases your ‘brown fat'. This is unlike normal fat, because it is packed with mitochondria which act like mini power stations, turning food into energy. What are the health benefits? Should we go lower than 19°? Should anyone not turn down the temperature? In under 3 minutes, we answer your questions! To listen to the latest episodes, click here: ⁠Can you get rid of cellulite?⁠ ⁠Do you know about home design maximalism?⁠ ⁠What is toxic positivity?⁠ A Bababam Originals podcast, written and produced by Amber Minogue. First Broadcast: 15/11/2022 Learn more about your ad choices. Visit megaphone.fm/adchoices

What if inflammation isn't something to "fight"… but a signal your nervous system can't turn off? In this powerful conversation, I'm joined by Kevin J. Tracey, MD — President and CEO of The Feinstein Institutes for Medical Research and a global leader in neuroimmunology and bioelectronic medicine. Dr. Tracey is best known for discovering the inflammatory reflex — the neural circuit through which the vagus nerve actively regulates the immune system. His work changed how we understand inflammation, chronic disease, recovery, and healing itself. And for high-performing, driven, midlife athletes and professionals… this science explains why so many people are stuck. In this episode, we connect Dr. Tracey's groundbreaking research directly into my FLOW Foundation™ framework:

This review series focuses on recent advances in resolving macro and molecular structures that have driven the field of occlusive thrombus structure and function forward. Covering multiple contributions to thrombosis, eg, platelets, factor XIII, and the contact system, the series also looks to put this new knowledge into the context of future advances in diagnostic and therapeutic tools to enhance normal hemostasis while preventing and treating unwanted thrombosis. Blood Associate Editor, Dr. Thomas Ortel discusses this series with Drs. Alisa Wolberg, Jonas Emsley, and John Weisel, who all contributed to articles in the Review Series on the Structural Underpinnings of Hemostatic Plugs and Thrombotic Occulsions which can be found in volume 146, issue 12 of Blood. 

In this episode of Better Thinking, Nesh Nikolic speaks with Professor Philip Batterham about advancing more efficient and precise methods for assessing suicidality and mental disorders.Philip Batterham is a Professor and Co-Head at the Centre for Mental Health Research, The Australian National University in Canberra, Australia. Phil is a research leader in improving access to evidence-based support for mental ill health and suicidal thoughts. He has specific interests in the etiology of suicidal behaviour, assessment of suicidality and mental disorders, implementation of online prevention programs, and reducing barriers to help seeking. Phil has published 320 journal articles and received >$50M in research funding as a Chief Investigator. He has received national and international awards for his research, including the Commonwealth Health Minister's Award for Excellence in Health and Medical Research, the Professor Vera Morgan Medal for Mental Health Epidemiology, and the inaugural NHMRC Peer Review Excellence Award. He currently leads a major longitudinal cohort study to better understand transitions into suicidal behaviour.

This week, we explore a new standard of care for high-risk HER2-positive early breast cancer, long-acting therapy for people with HIV facing adherence challenges, a first-in-class trial of a p53 reactivator, and tecovirimat for mpox. We review group B streptococcal disease and a revealing case of prosthetic joint infection. Perspectives examine the role of folate therapy, Medicare drug-price negotiation, AI in medical education, and incidental findings.

In the second part of this 20-Minute Health Talk podcast with Peter Hotez, MD, pediatrician, scientist and global health advocate, the conversation with host Chethan Sathya, MD, shifts to the front lines of health care. Dr. Hotez offers practical advice for clinicians and the public on navigating medical misinformation and myths, such as "turbo cancers.” He also reveals yet another good reason to get your Covid and flu shots — to protect your heart. As he explores the critical public health importance of childhood vaccines like the MMR and Hepatitis B, Dr. Hotez explains the real-world consequences of declining vaccination rates. Finally, he offers his frank assessment of the political and financial forces driving the anti-science movement and how to rebuild public trust. This is Part 2 of this series. Listen to Part 1 About Northwell Health Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch more episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

In this episode of 20-Minute Health Talk, host Chethan Sathya, MD, speaks with Peter Hotez, MD, pediatrician, scientist and global health advocate. Dr. Hotez shares the story behind his public advocacy: The "planned part" of his career — developing life-saving vaccines for the world's poor — and the "unplanned part" that began when his daughter, Rachel, was diagnosed with autism. Dr. Hotez explains how this experience thrust him into the center of the vaccine debate, which led to him becoming a target of the anti-vaccine movement. He and Dr. Sathya offer a behind-the-scenes look at the challenges of communicating evolving science to the general public. This is Part 1 of this series. Listen to Part 2 About Northwell Health Northwell is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Watch more episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

Vitamin D testing is vital for tailoring doses to optimize health—but regulators are conducting a campaign to deny coverage; Can magnesium be taken simultaneously with blood pressure meds? Lifelong learning delays Alzheimer's onset by 5 years; Your MRI says you have a bum shoulder—but 99% of people show abnormalities even when they have no discomfort; Saunas can help stave off dementia. 

Reflections on the Peter Attia/Epstein scandal; How to lower lp(a)—does diet help? What are bio-active peptides? Could they stave off kidney disease? Scientists just tested the fittest 81-year-old in the world—here's what they found; Media erroneously report that intermittent fasting is not effective for weight loss; Sugary drinks may stoke anxiety in teens; Omega-3s support kids' reading fluency and spelling scores; Surprising study shows saturated fats not harmful to kidneys.

Before he was even born, Sarah and Ross Gray knew that their son Thomas wouldn't live long. But as they let go of him, they made a decision that reverberated through a world that they never bothered to think about. Years later, after a couple of awkward phone calls, they go on a quest and manage to meet the people and places for whom Thomas' short life was an altogether different kind of gift. We originally made this story back in 2015, but we wanted to play it again because we love that it brings a view of science that is redemptive, tender, and unexpected. Since we first released this episode, Sarah Gray wrote a book called A Life Everlasting (https://zpr.io/GVYisRaqe9d6), it's a memoir about Thomas that dives into the world of organ donation and medical science. She's also written a beautiful short story about shame called The Lacemaker Fairy Tale (https://zpr.io/Li5BMtfHmf92). And, right now she's working on a script for a movie called Raincheck.EPISODE CREDITS: Reported by - Jad Abumrad with help from - Latif NasserLATERAL CUTS - The Cathedral (https://radiolab.org/podcast/cathedral) The Immortal Life of Henrietta Lacks (https://radiolab.org/podcast/the-immortal-life-of-henrietta-lacks)  Signup for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)! Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today. Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org. Leadership support for Radiolab's science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.

Antimicrobial resistance, or AMR, is often described as a silent pandemic. With antibiotics losing their effectiveness due to overuse and misuse, we look at how serious India's AMR burden is and why drug-resistant infections are rising. The Indian Express' Rinku Ghosh and Shashank Bhargava speak with Dr Kamini Walia of the Indian Council of Medical Research about what is driving this crisis and what can be done to slow it.Hosted by Ichha SharmaProduced and written by Shashank Bhargava and Ichha SharmaEdited and mixed by Suresh Pawar

Face transplant patient Robert Chelsea and writer Fay Bound Alberti talk through the promise – and darker side – of this pioneering surgery. Help support our independent journalism at theguardian.com/infocus

This week, we highlight major advances in multiple myeloma, gene therapy for cystinosis, and experimental treatments for myotonic dystrophy. We review long-term outcomes of aortic-valve replacement, strategies for secondary stroke prevention, and a revealing diagnostic case of eosinophilic disease in an older adult. A Sounding Board explores FDA approval standards. Perspectives delve into tobacco cessation, influenza evolution, and the uncertainty patients and clinicians share when facing life-altering diagnoses.

In this week's episode, Blood editor Dr. Laurie Sehn interviews authors Drs. Anastasios Karadimitris and Maria Carolina Florian on their papers published in Volume 147 Issue 2 of Blood. Dr. Karadimitris' paper "Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia", discusses the success of bispecific CAR-iNKT cells targeting CD19 and CD133 in pre-clinical models, prompting the clinical development of this class of product. Dr. Florian's paper, "A Notch trans-activation to cis-inhibition switch underlies hematopoietic stem cell aging" proposes that the Jagged2/Notch interaction is a key regulator of hematopoietic stem cell divisional symmetry during aging and offers insights that may inform strategies to restore regenerative function in aged hematopoiesis. 

This week includes studies on promising new therapies for IgA nephropathy, evolving antithrombotic strategies after coronary stenting, and the inciting antigen in rare vaccine-related clotting syndromes. We review the urgent challenge of mucormycosis and follow the case of a young woman with headaches and hypertension. We discuss human-subjects research. Perspectives examine rural health, data interoperability, drug labels in the courts, and a pediatrician's dilemma.

In part three of Northwell's 20-Minute Health Talk podcast, host Chethan Sathya, MD, and Jerome Adams, MD, former US Surgeon General, discuss the critical role of empathy and shared decision-making in healthcare communication, especially as public trust wavers. Amid rising frustrations with the healthcare system, Dr. Adams stresses the need for healthcare professionals to use empathetic, evidence-based dialogue to rebuild trust. He highlights the need for systemic change, advocating community engagement and upstream interventions in lieu of a mere sick-reimbursement model. He further reflects on his career trajectory and encourages aspiring physician leaders to leverage their credibility to make positive contributions, emphasizing continuous learning and adaptability in the evolving public health landscape. This is Part 3 of this series. Listen to Part 1 Listen to Part 2 About Northwell Health Northwell Health is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Get more expert insights from leading experts in the field — Northwell Newsroom.  Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

Host Chethan Sathya, MD, welcomes Jerome Adams, MD, US Surgeon General from 2016 to 2021 and author of Crisis and Chaos: Lessons from the Front Lines of the War Against Covid-19. In part one of this three-part series, Dr. Adams shares his journey from humble beginnings in rural Maryland to becoming a prominent public health leader. Despite facing personal health challenges and systemic barriers, Dr. Adams reflects on his resilient pursuit of a medical career, leading during Covid and his commitment to mentoring the next generation of health providers. He also discusses his experiences within the first Trump administration, the importance of representation in medicine and the critical need for diverse voices in public health discussions. This is Part 1 of this series. Listen to Part 2 Listen to Part 3 About Northwell Health Northwell Health is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Get more expert insights from leading experts in the field — Northwell Newsroom.  Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

In the second episode of Northwell's 20-Minute Health Talk podcast with Jerome Adams, MD, he and host Chethan Sathya, MD, discuss the pivotal role of election-year dynamics in shaping national and regional responses to the COVID-19 pandemic. Dr. Adams reflects on the challenge of balancing economic impacts with health mandates amid a politically charged atmosphere and how decision-making was swayed by partisan pressures. He highlights the importance of nuanced public health communication and the urgent need for healthcare professionals to prioritize empathy and understanding in patient interactions to convey crucial health information effectively. This is Part 2 of this series. Listen to Part 1 Listen to Part 3 About Northwell Health Northwell Health is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Get more expert insights from leading experts in the field — Northwell Newsroom.  Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

In this episode, Giovanni Piedimonte, MD, FAAP, FCCP, Professor of Pediatrics, Biochemistry, and Molecular Biology at Tulane University School of Medicine, discusses how artificial intelligence is transforming research, clinical care, and academic medicine. He also discusses the risks, ethical challenges, and workforce implications health systems must prepare for as AI adoption accelerates.

Send us a textUniversity of Maryland School of Medicine (UMSOM) associate professor Sarah M. Kattakuzhy, MD, joins “The UMB Pulse” this month to talk about her research exploring whether semaglutide (a GLP-1 medication widely used for diabetes and weight management) could help reduce cravings and improve outcomes for people with stimulant use disorder.Kattakuzhy, who is also the co-director of the Kahlert Institute for Addiction Medicine at UMSOM, describes the design of the STAC Study, which is evaluating the safety and tolerability of semaglutide in people with cocaine use disorder, including participants with and without HIV, while also tracking secondary outcomes such as changes in drug use and cravings.She also discusses why stimulant use disorders, including cocaine and methamphetamine use disorder, have been especially challenging to treat, and how her work through the University of Maryland, Baltimore community-based research partnerships aims to expand treatment options and reduce stigma around substance use disorders.To learn more about this trial or for referrals, contact Dr. Kattakuzhy at skattakuzhy@ihv.umaryland.edu.00:00 Introduction to Addiction and New Research00:40 Meet Dr. Sarah Kattakuzhy01:45 A Day in the Life of Dr. Kattakuzhy03:57 The Journey to Addiction Research07:40 Exploring Semaglutides for Addiction Treatment12:34 Details of the Clinical Trial20:29 Challenges and Hopes in Addiction Treatment24:31 Collaborations and Future Directions27:39 Final Thoughts and Takeaways32:13 Post-Interview InsightsListen to The UMB Pulse on Apple, Spotify, Amazon Music, and wherever you like to listen. The UMB Pulse is also now on YouTube.Visit our website at umaryland.edu/pulse or email us at umbpulse@umaryland.edu.

In this week's episode, Blood editor Dr. James Griffin interviews Drs. Paresh Vyas and Andrew Hantel on their research published in this week's issue of Blood. Dr. Vyas discusses his paper, "Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy", which provided new insights as to when and how to intervene to circumvent resistance to AML remission. Dr. Hantel will speak about his paper, "Impact of Modernizing Eligibility Criteria on Enrollment and Representation in AML Clinical Trials". For a real-world cohort of more than 2200 patients with AML, they reported that modernized, safety-based criteria could nearly double trial eligibility, with especially pronounced gains among historically underserved groups.  Both studies highlight how biologic insight and thoughtful trial design can drive more effective, inclusive advances in AML treatment and research. 

This week, we look at new evidence on oral cholesterol-lowering therapy, the evolving role of beta-blockers after myocardial infarction, and advances in breast and prostate cancer treatment. We review the inherited risk of coronary disease. We also work through a revealing diagnostic case in a young woman and reflect on science under pressure, corporatized insurance, the reach of FDA law, and what it means to live with life-sustaining technology.

Is modern medicine still evidence-based, or have we quietly mistaken rigor for certainty?Evidence-based medicine is essential. It's why we save lives, advance care, and trust modern healthcare. But as medicine has become more specialized and disease more complex, something subtle has happened. Rigor has increasingly turned into reductionism, and evidence is often applied in ways that don't fully match the realities of clinical practice or patients' lived experiences.In this episode of The Trip Lab, I take a careful look at what we mean when we say “evidence-based medicine.” We explore the difference between statistical significance and clinical significance, how guidelines are created and why they are evidence-informed rather than infallible, and why many patients feel unwell despite having “normal” labs.This conversation also examines how modern research methods struggle to capture complexity, particularly in chronic, system-level disease. We look at where reductionism has helped medicine advance, where it now falls short, and why ancient healing systems and emerging fields like systems biology, functional medicine, and precision medicine are pointing us toward a more integrated future.This episode is not a rejection of evidence. It's an invitation to reclaim it. To restore clinical wisdom alongside data, and to practice medicine with both rigor and curiosity.In this episode, we cover:What “evidence-based medicine” actually means and how it's evolvedStatistical significance vs. clinical significanceThe strengths and limitations of medical guidelinesWhy reductionist models don't fully explain chronic diseaseWhy patients can feel unwell even when labs are “normal”How medicine might evolve to better study complexityWhy medicine is both a science and an artThe podcast name, The Trip Lab, nods to psychedelics, but a “trip,” psychedelic or otherwise, is ultimately an exploration. A willingness to step outside familiar frameworks, question what we think we know, and notice connections that weren't obvious before.If you've ever felt tension between what the data says, what the guidelines allow, and what the patient in front of you actually needs... or if you are a patient who has been failed by modern medicine, this episode is for you.

From COVID-19 research to Parkinson's disease therapies, these statistical experts turn numbers into answers, helping doctors make evidence-based decisions that improve patient care.

Last year, the National Institutes of Health drastically cut funding for medical research. This disrupted the work of academics and researchers across the country. Clinical trials and scientific projects were cancelled, and funding for ongoing research was revoked. This meant big cuts in funding to research institutions here in Connecticut. UConn lost $41 million from research grant terminations and unexpected non-renewals. Today, we hear how these cuts are impacting research institutions in our state and the future of science. GUESTS: Rob Stein: Correspondent and Senior Editor, on NPR’s Science Desk Evan Morris: Professor of Radiology and Biomedical Imaging and of Biomedical Engineering at Yale School of Medicine Diane Owens: mother of a pediatric patient with neurofibromatosis Support the show: http://wnpr.org/donateSee omnystudio.com/listener for privacy information.

This week, we explore new therapies to reduce pancreatitis risk in severe hypertriglyceridemia, advances in breast cancer treatment, and long-term results of gene therapy for hemophilia B. We discuss vision-threatening vascular emergencies, the mental health effects of firearm injury on families, and care for peripheral artery disease. We also follow a revealing diagnostic case in an older woman with respiratory failure. Perspectives reflect on hypertension control, immunization access, chronic disease policy, and on the inherited risk of disease.

In the final segment of this three-part series, host Chethan Sathya, MD, and former NYC Health Commissioner Ashwin Vasan, MD, discuss the critical need for rebuilding trust in public health. Dr. Vasan emphasizes the importance of open dialogue and empathetic engagement across communities, highlighting the challenges posed by societal divisions. As public health faces skepticism, he underscores the need to involve diverse perspectives to foster unity and chart a path toward a healthier, more inclusive future. This is Part 3 of this series. Listen to Part 1 Listen to Part 2 About Northwell Health Northwell Health is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Get more expert insights from leading experts in the field — Northwell Newsroom.  Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

Join host Chethan Sathya, MD, and former NYC Health Commissioner Ashwin Vasan, MD, for part two of our series exploring public health challenges. In this segment, Dr. Vasan addresses the opioid crisis, his leadership during tumultuous times, and the essential role of resilience. He shares insights from his diverse roles, highlighting the successful reduction in overdose deaths and how volatility spurred transformative strategies, ranging from mental health initiatives to efforts to tackle social media's impact. This is Part 2 of this series. Listen to Part 1 Listen to Part 3 About Northwell Health Northwell Health is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Get more expert insights from leading experts in the field — Northwell Newsroom.  Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

Host Chethan Sathya, MD, discusses the challenges and opportunities of improving public health with the former commissioner of NYC's Department of Health and Mental Hygiene, Ashwin Vasan, MD. In this 3-part conversation, Dr. Vasan delves into his inspiring journey into medicine. With family tragedies, namely polio, and successes fueling his passion, Dr. Vassan discusses the vital role of storytelling in enacting systemic change. Guided by influential mentors, he emphasizes the need for engagement, empathy, and impactful results in public health initiatives. This is Part 1 of this series. Listen to Part 2 Listen to Part 3 About Northwell Health Northwell Health is New York State's largest healthcare provider and private employer, with 28 hospitals, 890 outpatient facilities and more than 16,600 affiliated physicians. We're making breakthroughs in medicine at the Feinstein Institutes for Medical Research. We're training the next generation of medical professionals at the visionary Donald and Barbara Zucker School of Medicine at Hofstra/Northwell and the Hofstra Northwell School of Nursing and Physician Assistant Studies. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Get the latest news and insights from our experts in the Northwell Newsroom: Press releases Insights Podcasts Publications Interested in a career at Northwell Health? Visit our career site and explore our many opportunities. Get more expert insights from leading experts in the field — Northwell Newsroom.  Watch episodes of 20-Minute Health Talk on YouTube.  For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. 

In this episode, we explore evolving evidence on anticoagulation after atrial fibrillation ablation, long-term outcomes with immunotherapy for melanoma, and promising new treatments for hepatitis D and triple-negative breast cancer. We review advances in physiologic pacing for heart failure and work through a challenging case involving fever, rash, and neurologic symptoms. An article considers fairness for late-career physicians, and Perspectives discuss misconceptions about autism, access to contraception, and the financial pressures shaping health care.

Ian Sample puts listeners' questions on sleep to Dr Allie Hare, consultant physician in respiratory and sleep medicine at Guy's and St Thomas' hospitals and president of the British Sleep Society. They cover why women experience sleep disturbance during the menopause, why sleep paralysis affects some people more than others, and what scientists know about the link between sleep and dementia. Hare also gives her top tips for getting better sleep in 2026. Help support our independent journalism at theguardian.com/sciencepod

When neuroscientist Madeline Lancaster was a brand new postdoc, she accidentally used an expired protein gel in a lab experiment and noticed something weird. The stem cells she was trying to grow in a dish were self-assembling. The result? Madeline was the first person ever to grow what she called a “cerebral organoid,” a tiny, 3D version of a human brain the size of a peppercorn.In about a decade, these mini human brain balls were everywhere. They were revealing bombshell secrets about how our brains develop in the womb, helping treat advanced cancer patients, being implanted into animals, even playing the video game Pong. But what are they? Are these brain balls capable of sensing, feeling, learning, being? Are they tiny, trapped humans? And if they were, how would we know?Special thanks to Lynn Levy, Jason Yamada-Hanff, David Fajgenbaum, Andrew Verstein, Anne Hamilton, Christopher Mason, Madeline Mason-Mariarty, the team at the Boston Museum of Science, and Howard Fine, Stefano Cirigliano, and the team at Weill-Cornell. EPISODE CREDITS: Reported by - Latif Nasserwith help from - Mona MadgavkarProduced by - Annie McEwen, Mona Madgavkar, and Pat Walterswith mixing help from - Jeremy BloomFact-checking by - Natalie Middleton and Rebecca Randand Edited by  - Alex Neason and Pat WaltersEPISODE CITATIONS:Videos - “Growing Mini Brains to Discover What Makes Us Human,” Madeline Lancaster's TEDxCERN Talk, Nov 2015 (https://zpr.io/6WP7xfA27auR)Brain cells playing Pong (https://zpr.io/pqgSqguJeAPK)Reuters report on CL1 computer launch in March 2025 (https://zpr.io/cdMf8Yjvayyd) Articles - Madeline Lancaster: The accidental organoid – mini-brains as models for human brain development (https://zpr.io/nnwFwUwnm2p6), MRC Laboratory of Molecular Biology What We Can Learn From Brain Organoids (https://zpr.io/frUfsg4pxKsb), by Carl Zimmer. NYT, November 6, 2025Ethical Issues Related to Brain Organoid Research (https://zpr.io/qyiATHEhdnSa), by Insoo Hyun et al, Brain Research, 2020 Brain organoids get cancer, too, opening a new frontier in personalized medicine (https://zpr.io/nqMCQ) STAT Profile of Howard Fine and his lab's glioblastoma research at Weill Cornell Medical Center: By re-creating neural pathway in dish, Stanford Medicine research may speed pain treatment (https://zpr.io/UnegZeQZfqn2) Stanford Medicine profile of Sergiu Pasca's research on pain in organoids A brief history of organoids (https://zpr.io/waSbUCSrL9va) by Corrò et al, American Journal of Physiology - Cell Physiology, Books - Carl Zimmer Life's Edge: The Search for What it Means to be Alive (https://carlzimmer.com/books/lifes-edge/)Sign up for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Signup (https://radiolab.org/newsletter)!Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.Leadership support for Radiolab's science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.

In the last year, you've basically replaced your body weight in new cells. So yes, it's a new year, new you. To ring in 2026, we're talking about starting anew, and drawing inspiration from tiny worms that embody the ultimate growth mindset—they can regrow a whole body from just a tiny piece of their tail. In this festive episode, Host Flora Lichtman talks with biologist Alejandro Sánchez Alvarado, a pioneer in the field of regeneration, about the science of regeneration and the biology lessons we can carry into the new year. Guest: Dr. Alejandro Sánchez Alvarado is a biologist and president and chief scientific officer of the Stowers Institute for Medical Research in Kansas City, Missouri.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.