Podcasts about cshl

(AURN News) – Scientists at the Cold Spring Harbor Laboratory Cancer Center (CSHL) have identified stress as a major contributor not only to heart disease and stroke but also to the metastasis of cancer.  Former postdoc for CSHL, Xue-Yan He, emphasized the inevitability of stress in cancer patients. “Stress is something we cannot really avoid in cancer patients. You can imagine if you are diagnosed, you cannot stop thinking about the disease or insurance or family. So it is very important to understand how stress works on us,” He said. The research conducted by the scientists sheds light on the profound impact of stress on specific white blood cells, rendering them more susceptible to metastasis. By replicating chronic stress conditions in mice with cancer, the researchers observed a notable increase in the spread of cancer cells. The groundbreaking study not only underscores the psychological toll that a cancer diagnosis takes on individuals, but also highlights the tangible physiological consequences as well. Learn more about your ad choices. Visit megaphone.fm/adchoices

Arkarup Banerjee | School of Biological Science / Cold Spring Harbor Laboratory, NY "Neural Circuits for Vocal Communication: Insights from the Singing Mice." My long-standing interest is to understand how circuits of interacting neurons give rise to natural, adaptive behaviors. Using vocal communication behavior across rodent species, my lab at CSHL pursues two complementary questions. How does the auditory system interact with the motor system to generate the fast sensorimotor loop required for vocal communication? What are the neural circuit modifications that allow behavioral novelty to emerge during evolution? In this talk, I will introduce you to the rich vocal life of the Costa-Rican singing mice. Next, I will describe a series of experiments that were performed to demonstrate the role of the motor cortex in controlling vocal flexibility in this species. In closing, I will discuss our ongoing efforts to identify neural circuit differences between singing mice and lab mice using high-throughput connectomics. Together, by combining neural circuit analysis of a natural behavior with comparative evolutionary analyses across species, we stand to gain insight into the function and evolution of neural circuits for social behaviors.

James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper proposing the double helix structure of the DNA molecule. Watson, Crick and Maurice Wilkins were awarded the 1962 Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material". Watson earned degrees at the University of Chicago (BS, 1947) and Indiana University (PhD, 1950). Following a post-doctoral year at the University of Copenhagen with Herman Kalckar and Ole Maaløe, Watson worked at the University of Cambridge's Cavendish Laboratory in England, where he first met his future collaborator Francis Crick. From 1956 to 1976, Watson was on the faculty of the Harvard University Biology Department, promoting research in molecular biology. From 1968, Watson served as director of Cold Spring Harbor Laboratory (CSHL), greatly expanding its level of funding and research. At CSHL, he shifted his research emphasis to the study of cancer, along with making it a world-leading research center in molecular biology. In 1994, he started as president and served for 10 years. He was then appointed chancellor, serving until he resigned in 2007 after making comments claiming that there is a genetic link between intelligence and race. In 2019, following the broadcast of a documentary in which Watson reiterated these views on race and genetics, CSHL revoked his honorary titles and severed all ties with him. Watson has written many science books, including the textbook Molecular Biology of the Gene (1965) and his bestselling book The Double Helix (1968). Between 1988 and 1992, Watson was associated with the National Institutes of Health, helping to establish the Human Genome Project, which completed the task of mapping the human genome in 2003. ___________________________________________________________ Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical structure of the DNA molecule. Crick and Watson's paper in Nature in 1953 laid the groundwork for understanding DNA structure and functions. Together with Maurice Wilkins, they were jointly awarded the 1962 Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material". Crick was an important theoretical molecular biologist and played a crucial role in research related to revealing the helical structure of DNA. He is widely known for the use of the term "central dogma" to summarise the idea that once information is transferred from nucleic acids (DNA or RNA) to proteins, it cannot flow back to nucleic acids. In other words, the final step in the flow of information from nucleic acids to proteins is irreversible. During the remainder of his career, he held the post of J.W. Kieckhefer Distinguished Research Professor at the Salk Institute for Biological Studies in La Jolla, California. His later research centered on theoretical neurobiology and attempts to advance the scientific study of human consciousness. He remained in this post until his death; "he was editing a manuscript on his death bed, a scientist until the bitter end" according to Christof Koch. Original video ⁠here⁠⁠ Full Wikipedia entry ⁠for James Watson here⁠ | James Watson's books here Full Wikipedia entry ⁠for Francis Crick here⁠ | Francis Crick's books here --- Support this podcast: https://podcasters.spotify.com/pod/show/theunadulteratedintellect/support

Everyone knows that we are not all the same, there is wonderful diversity in our bodies, our genetics, our lifestyles, and our preferences. And yet, when it comes to nutrition, the most successful public health messages are the broad guidelines, which suggests one size can fit all.   Think five-a-day, taking Vitamin D through the autumn and winter, and so on. At the same time, the science behind nutrition, the understanding of our metabolism and of our gut microbiome, has been increasing at a fantastic rate. The question is: how do you bring these two worlds together?   How do you bring the best of intricate nutritional science to a broader population? Could the answer lay in precision nutrition?   It is an emerging and exciting field which helps tailor dietary recommendations and nutritional guidelines, and there is some evidence it can have remarkable health impacts. It is an area which seems to offer huge potential, but exactly how much is yet to be discovered. Karen Vousden, Principal Group Leader, Francis Crick Institute Karen received her PhD from the University of London and following postdoctoral fellowships at the ICR and NCI, she returned to London to establish a research group at the Ludwig Institute.  Returning to the US, she was Chief of the Regulation of Cell Growth Laboratory at the NCI before coming back to the UK to take on the role of Director of the CRUK Beatson Institute in Glasgow.   In 2017, she moved her research group to the Francis Crick Institute in London and served as Chief Scientist for Cancer Research UK from 2016-2022. Karen's research has made contributions to our understanding of how the tumour suppressor protein p53 is regulated and the functions of p53 that contribute to its ability to control cancer progression.   During these studies, her group revealed an unexpected ability of p53 to help cells adapt and survive under transient periods of nutrient starvation.  This work led to a more general investigation of cancer cell metabolism, focused on exploring the role of oxidative stress and serine metabolism in cancer development and metastatic progression. Greg Hannon, Director of Cancer Research UK Cambridge Institute Greg Hannon FRS FMedSci is a professor of molecular cancer biology and director of the Cancer Research UK Cambridge Research Institute at the University of Cambridge.   Professor Hannon is internationally recognised for his contributions to small RNA biology, cancer biology, and mammalian genomics.  He has a long history in the discovery of cancer genes, beginning with work at CSHL that led to the identification of CDK inhibitors and their links to cancer.   More recently, his work has focused on small RNA biology, which led to an understanding of the biochemical mechanisms and biological functions of RNAi.   Building upon this foundation, he has developed widely-used tools and strategies for manipulation of gene expression in mammalian cells and animals and has generated genome-wide shRNA libraries that are available to the cancer community.   He was among the first to uncover roles for microRNAs in cancer, including the discovery of the miR-17-92 cluster as an oncogene, the placement of miR-34 within the p53 pathways, and the understanding that let-7 and miR-93 are critical regulators of both normal stem cells and tumour initiating cells in several tissues.   His laboratory also discovered the piRNA pathway and linked this to transposon repression and the protection of germ cell genomes. 

We're recapping the CSHL championship game that saw Washington-Liberty take down West Potomac 5-2 to conclude a great season. We're breaking down the Generals Elite run to a national championship and to figure out how they went 3-1 but didn't make the final? The Black Bears end their losing streak and pick up a big two points at home over the weekend. 

It's the CSHL championship game day and we've got Washington-Liberty Head Coach Matt Seney and West Potomac Head Coach Brian McCullough on to break down tonights big game and give insights into their respective teams, what they need to do to beat their opponent, and how they plan to fire their teams up since they can't use locker rooms. We're also joined by Isaac Blank, the Captain of the MSHL State Champion BCC hockey team who talks their run to the title, his future in the game, and training at First Line. 

We're breaking down tonights big game between West Potomac and Washington-Liberty as they go head to head for the league championship. We're telling ya how they got there and making our predictions. We shout out the BI Cardinals for a hell of a job with social media. We're also talking all things Richmond Generals and Hampton Road Whalers as they prepare for deep runs to the USPHL National Championships. 

It's a shorter episode but we're talking all things high school hockey. We're breaking down the CSHL bracket and looking at the games ahead tonight and how those teams got here, and how one team is using coach's doubt as motivation. We're touching on the quickly completed NVSHL playoffs and taking a sneak peak at the MSHL playoffs. We kick the episode off with Stevenson Mustangs coach Urgo who breaks some news and talks expansion. 

It's a playoff hockey night in the DMV as the CSHL and NVSHL both kick off the first round of their brackets tonight and we're breaking down the brackets and making our predictions. We're joined by Matt Berry, Captain of the Snow Monkeys pond hockey team recapping their tournament in Colorado. We break down the USPHL and Black Bears weekends and finish the episode with Forward for TM EHL Evan Donnelly who talks current state of the team and Spalding career. 

We're kicking things off with high school hockey and an undefeated team going down in the CSHL as the playoff race tightens up. We're then joined by Andrew Takacs, DeMatha and TM alum who played for the Maryland Black Bears and now for the Amarillo Bulls in the NAHL. We talk his start in hockey, championship run at DeMatha, and what the future holds. We then talk some junior hockey and wrap up with R.C. Lyke, head coach of the Richmond Generals, who gives us an update on their Premier and Elite teams. 

Another local Friday puck talk episode and we're talking all things CSHL, NVSHL, and MAPHL as the playoff push is on and each team faces 1-2 games remaining. We're talking Liberty's big win over NCAA D1 Long Island University. We're joined by Kris Carlson, Virginia native and goalie for the UAA Seawolves talking Little Caps, TM, leaving Providence and his time in multiple junior leagues. We finish with a Black Bears win over Maine, TM EHL, and Gratton gets a win. 

On another loaded episode of local puck talk, we've got another three interviews, starting with Wilson Drake, the host of the "Fire in the Hole" podcast, a kids hockey podcast bringing you a joke of the day and all things youth hockey. We talk his favorite podcast, why he started podcasting, and his young hockey career. We're also joined by Brian McCullough, head coach of the undefeated West Potomac High School team competing in the CSHL. He breaks down his teams hot start and what they need to do to win state. Finally, we're joined by Maryland native and defenseman for the London Knights, Bryce Montgomery, who talks his career in the DMV, how he got to the OHL, and why he chose it over college. 

Au menu de ce podcast : - L'Esperance champion pour la 30e fois et 4e fois de suite. Nos avis sur ce titre ? - Soliman et Chebba qui se maintiennent après leur première saison en LP1 ! Quelle performance - La lutte pour le maintien : CAB, JSK, CSHL, Metlaoui ... - Mercato : Henid ? Batbout ?

The big man of the CSHL, Lou Harvitan, is back!  How do you run a league from a whole different state?  Wouldn't you like to know?  Plus, can't leave your house doesn't mean can't enjoy hockey.  And Gritty, ever and always. Our train of thought is a runaway. Check out the exclusive content on our YouTube channel.  Stay current with us on Twitter, Facebook, and Instagram.

It's a championship episode as we round up the high school season and look at the champs from all four leagues. We're joined by Coach Erickson from the Landon Bears to talk about their dream season, as well as three players from the Lake Braddock team who just won their first CSHL title. We're also joined by Rob from the DC Fire team, who just won the Maryland Hero's Hockey League championship. 

It's championship Friday in the MSHL, NVSHL, and CSHL as we recap playoffs for all the high school leagues and run through the all league team selections. We're joined by Gavin Ross from Marriotts Ridge who chats the semi-final loss to Churchill, and we're also joined by Richmond Generals coach RC Lyke who previews the playoff series vs Hampton Roads this weekend. 

Happy Tuesday.. AKA HAPPY PLAYOFFS!! MAPHL quarterfinals kick off today, MSHL playoffs get started this week, and the CSHL is off to round two. We're joined by Landon coach David Erickson talking Landon's hopes at a 'ship and their dominate IAC championship win. We're also joined by Glenelg stud Tommy Tracy as his squad get's ready for a tough playoff slate at the #1 seed in the state. Lastly, we're joined by Navy hockey captain Derek Golembrosky who previews the annual Crab Pot tournament this coming weekend. 

Local puck and its all high school hockey in the DMV as it's the last day of the regular season and the playoff race is on. We're joined by CSHL board member and scheduler Matt Seney, MSHL Executive Director Joe LaCour, and Chantilly head coach John Mercer. Coach breaks down the MAPHL playoff picture as St John's aims to get the top seed. New segment Throwback Thursday where the boys throw back some beers and remember youth stories. 

This episode is a panel discussion recorded as Part I of a two part series on the recent Present & Future Frameworks in Theoretical Neuroscience, an international workshop hosted by Horacio Rotstein (NJIT) & Fidel Santamaria (UTSA) with support from the NSF’s Brain Initiative. Part I is a preamble recorded on day one of the meeting, in which some friends of the podcast (see below) define the need for the workshop and identify their objectives as they undertake their workgroups. Hosted by Salma Quraishi.Stay tuned for Part II, which was recorded at the close of the workshop. Part II will be posted separately as a follow up to summarize some of the critical discussions that transpired in the workgroups. Duration: 33 minutesPanel:(in alphabetical order, pictured left to right)Veronica Alvarez, Senior Investigator, IRP NIAAAAlain Destexhe, Research Director, CNRS ParisTatiana Engel, Assistant Professor, CSHLHoracio Rotstein, Professor, NJITDavid Redish, Distinguished McKnight Professor, University of MinnesotaFidel Santamaria, Professor, UTSARecorded at the Emily Morgan Hotel, San Antonio TX.acknowledgement: JM Tepper for original music.

What is it about teachers that make them so hot? According to the popular college professor reviewing website, Rate My Professors, it’s more than just looks. But how does their rating system work? How are female professors rated versus their male peers? In Episode 52, Dr. Zhana and Joe talk to New York University professor Pascal Wallisch about how students rate and tag their favorite (or not-so-favorite) professors on the divisive yet popular website, Rate My Professors. Does the site enable students to label their professors in a way that affirms gender stereotypes? And while Dr. Zhana and Pascal savor their hot pepper status, some professors would prefer that not to be a factor. Also— do you know the difference between a psychopath and a sociopath? Pascal provides us with some more info on the 1% of the population who is psychopathic and answers the first question on our minds— do they have sex? Tune in to learn more! About our Guest https://scienceofsexpodcast.com/wp-content/uploads/2018/12/Pascal.gif ()Pascal Wallisch serves as clinical assistant professor at New York University, heading the Fox lab. Pascal received a PhD in Psychology from the University of Chicago. Wallisch’s main research interests lie at the intersection of neuroscience, psychology, and data science. Pascal co-founded the “Neural Data Science” summer course at CSHL and wrote several books on the analysis of data in neuroscience. Pascal’s efforts were recognized with the “Golden dozen” teaching award by NYU.   Before Next Time… Remember to like The Science of Sex Podcast on https://www.facebook.com/ScienceofSexPodcast/ (Facebook), https://twitter.com/ScienceofSexPod (Twitter), and https://www.instagram.com/scienceofsexpodcast/ (Instagram)! Also check Dr. Zhana out on December 11th at The V Club where she teams up with one of our favorite researchers, Dr. Justin Lehmiller, to discuss one of our most popular topics: gender differences in sexuality. RSVP to https://thevclub.com/mars-venus-debate-workshop/ (The Mars/Venus Debate: Are Men and Women Really That Different When It Comes to Sex?) here. Visit https://lelo.to/ny0gc (Lelo) to fulfill your high-quality vibrator needs with a wide selection of vibrators for all! Use discount code SCIENCE to get 20% off on your new vibrating toy. Visit https://www.adameve.com (Adam & Eve) and use promo code SCIENCE for 50% off just about any product. Plus 3 FREE adult DVDs, FREE mystery gift and FREE shipping. Remember to submit comments, questions, and everything in between on our Get in Touch Page! For more sex science articles, events and discussions please join our https://www.facebook.com/groups/1930239240355951/ (Science of Sex Facebook group)! Do you love The Science of Sex Podcast and all the work Dr. Zhana does? Support her by becoming a monthly https://www.patreon.com/drzhana (Patreon Supporter)! Facebook Twitter Google+ Pinterest LinkedIn 35Shares

Jake and I catch up and revisit the absolute absurdity that was our time together in the CSHL - a Junior A tier-III league that no longer exists.

You may have heard of it; "immunotherapy" has started to appear in headlines over the last few years. In this episode, however, we reveal that the practice of cancer immunotherapy is actually far older than even our understanding of the immune system! We also talk to a CSHL researcher who is showing that the immune system doesn’t even need to be engineered to kill cancer. It just needs to be unleashed.

In this episode, we are talking to Jackie Giovanniello, a Ph.D. student in Neuroscience at Cold Spring Harbor Laboratory in NY. She works on understanding how neural circuits are disrupted in autism. She is also the Co-Founder of the Women in Science & Engineering Initiative (WiSE) at CSHL. Learn how she got over challenges and succeeded in securing 30,000 dollars in funding with over 100 members. Jackie shares her struggles, strengths, and ideas to get more women to wear & retain the pristine white lab coats! Links: CSHL WISE www.500womenscientists.org Twitter: @CSHL_WISE

Who will use CRISPR to alter their child's DNA? Who gets to decide which traits are desirable? Following up on our last episode, "Good Genes, Bad Science," we hear from David Micklos, executive director at CSHL’s DNA Learning Center, and Miriam Rich, CSHL Archives Sydney Brenner Research Scholar and doctoral student at Harvard, on these big questions.

Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Vincent, Alan, and Kathy discuss new influenza virus NA inhibitors, detection of EEEV antibody and RNA in snakes, and replication of the coronavirus EMC in human airway epithelial cells. Links for this episode: International Women's Day 2013 Condit Dam, 6 weeks later (Vimeo) Influenza HA assay Covalent influenza NA inhibitors (ScienceExpress) Defective influenza HA mutants (Virology) New flu drug (BBC, e! Science) EEEV antibody, RNA in snakes (Am J Trop Med Hyg) EEEV (CDC) Zoonotic potential of CoV-EMC (mBio) CoV-EMC update (ProMedMail, CDC) CoV-EMC travel update (CDC) Letters read on TWiV 223 Weekly Science Picks Kathy - Finkbeiner test and Women in ScienceAlan - New flu vaccine efficacy study (CDC)Vincent -  Threading the NEIDL video Listener Pick of the Week Steve - Prof. Joan Steitz on viral RNAEd - Archiving history of molecular biology: Press release, video, CSHL archives and videos Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv