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CardioNerds (Dr. Shazli Khan, Dr. Jenna Skowronski, and Dr. Shiva Patlolla) discuss the management of patients post‑heart transplantation with Dr. Shelley Hall from Baylor University Medical Center and Dr. MaryJane Farr from UTSW. In this comprehensive review, we cover the physiology of the transplanted heart, immunosuppression strategies, rejection surveillance, and long-term complications including cardiac allograft vasculopathy (CAV) and malignancy. Audio editing for this episode was performed by CardioNerds intern Dr. Bhavya Shah. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Heart Success Series PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls The Denervated Heart: The donor heart is surgically severed from the autonomic nervous system, leading to a higher resting heart rate (90-110 bpm) due to loss of vagal tone. Because the heart relies on circulating catecholamines rather than neural input to increase heart rate, patients experience a delayed chronotropic response to exercise and stress. Importantly, because afferent pain fibers are severed, ischemia is often painless. Rejection Surveillance: Rejection is classified into Acute Cellular Rejection (ACR), which is T-cell mediated, and Antibody-Mediated Rejection (AMR), which is B-cell mediated. While endomyocardial biopsy remains the gold standard for diagnosis, non-invasive surveillance using gene-expression profiling (e.g., AlloMap) and donor-derived cell-free DNA (dd-cfDNA) is increasingly utilized to reduce the burden of invasive procedures. The Infection Timeline: The risk of infection follows a predictable timeline based on the intensity of immunosuppression. The first month is dominated by nosocomial infections. Months one through six are the peak for opportunistic infections (Cytomegalovirus, Pneumocystis, Toxoplasmosis) requiring prophylaxis. After six months, patients are primarily at risk for community-acquired pathogens, though late viral reactivation can occur. Cardiac Allograft Vasculopathy (CAV): Unlike native coronary artery disease, CAV presents as diffuse, concentric intimal thickening that affects the entire length of the vessel, including the microvasculature. Due to denervation, patients rarely present with angina; instead, CAV manifests as unexplained heart failure, fatigue, or sudden cardiac death. Malignancy Risk: Long-term immunosuppression significantly increases the risk of malignancy. Skin cancers (squamous and basal cell) are the most common, followed by Post-Transplant Lymphoproliferative Disorder (PTLD), which is often driven by Epstein-Barr Virus (EBV) reactivation. Notes Notes: Notes drafted by Dr. Patlolla 1. What are the unique physiological features of the transplanted heart? The hallmark of the transplanted heart is denervation. Because the autonomic nerve fibers are severed during harvest, the heart loses parasympathetic or vagal tone, resulting in a resting tachycardia (typically 90-110 bpm). The heart also loses the ability to mount a reflex tachycardia; thus, the heart rate response to exercise or hypovolemia relies on circulating catecholamines, which results in a slower “warm-up” and “cool-down” period during exertion. 2. What are the pillars of maintenance immunosuppression regimen? The triple drug maintenance regimen typically consists of: Calcineurin Inhibitor (CNI): Tacrolimus is preferred over cyclosporine. Key side effects include nephrotoxicity, hypertension, tremor, hyperkalemia, and hypomagnesemia. Antimetabolite: Mycophenolate mofetil (MMF) inhibits lymphocyte proliferation. Key side effects include leukopenia and GI distress. Corticosteroids: Prednisone is used for maintenance but is often weaned to low doses or discontinued after the first year to mitigate metabolic side effects (diabetes, osteoporosis, weight gain). 3. How is rejection classified and diagnosed? Rejection is the immune system’s response to the foreign graft and is categorized by the arm of the immune system involved: Acute Cellular Rejection (ACR): Mediated by T-lymphocytes infiltrating the myocardium. It is graded from 1R (mild) to 3R (severe) based on the extent of infiltration and myocyte damage. Antibody-Mediated Rejection (AMR): Mediated by B-cells producing donor-specific antibodies (DSAs) that attack the graft endothelium. It is diagnosed via histology (capillary swelling) and immunofluorescence (C4d staining). Diagnosis has historically relied on endomyocardial biopsy. However, non-invasive tools are gaining traction. Gene Expression Profiling (GEP) assesses the expression of genes associated with immune activation to rule out rejection in low-risk patients. Donor-Derived Cell-Free DNA (dd-cfDNA) measures the fraction of donor DNA in the recipient’s blood. Elevated levels suggest graft injury which can occur in both ACR and AMR. 4. What is the timeline of infectious risk and how does it guide prophylaxis? Infectious risk correlates with the net state of immunosuppression. < 1 Month (Nosocomial): Risks include surgical site infections, catheter-associated infections, and aspiration pneumonia. 1 – 6 Months (Opportunistic): This is the period of peak immunosuppression. Patients are at risk for PJP, CMV, Toxoplasma, and fungal infections. Prophylaxis typically includes Trimethoprim-Sulfamethoxazole (for PJP/Toxo) and Valganciclovir (for CMV, dependent on donor/recipient serostatus). > 6 Months (Community-Acquired): As immunosuppression is weaned, the risk profile shifts toward community-acquired respiratory viruses (Influenza, RSV) and pneumonias. However, patients with recurrent rejection requiring boosted immunosuppression remain at risk for opportunistic pathogens. 5. How does Cardiac Allograft Vasculopathy (CAV) differ from native CAD? CAV is the leading cause of late graft failure. Unlike the focal, eccentric plaques seen in native atherosclerosis, CAV is an immunologically driven process causing diffuse, concentric intimal hyperplasia. It affects both epicardial vessels and the microvasculature. Because of this diffuse nature, percutaneous coronary intervention (PCI) is often technically difficult and provides only temporary palliation. The only definitive treatment for severe CAV is re-transplantation. Surveillance is critical and is typically performed via annual coronary angiography, often using intravascular ultrasound (IVUS) to detect early intimal thickening before it is visible on the angiogram. References Costanzo MR, Dipchand A, Starling R, et al. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Heart Lung Transplant. 2010;29(8):914-956. doi:10.1016/j.healun.2010.05.034. https://www.jhltonline.org/article/S1053-2498(10)00358-X/fulltext Kittleson MM, Kobashigawa JA. Cardiac Allograft Vasculopathy: Current Understanding and Treatment. JACC Heart Fail. 2017;5(12):857-868. doi:10.1016/j.jchf.2017.07.003. https://www.jacc.org/doi/10.1016/j.jchf.2017.07.003 Velleca A, Shullo MA, Dhital K, et al. The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Heart Lung Transplant. 2023;42(5):e1-e141. doi:10.1016/j.healun.2022.10.015. https://www.jhltonline.org/article/S1053-2498(22)02187-5/fulltext
Love the show? Have any thoughts? Click here to let us know!This is the first week without our fabulous Lauren as we head towards the bitter cold of the Last Frontier State, Alaska. Kenzie's cousin, Emily, joins her to discuss the brutal crimes of maybe-kinda-sorta serial killer, Brian Steven Smith. Police believe they have all the evidence and answers they need, but little did they know that Mr. Smith had more to share. If it wasn't for the bravery of two women in the Anchorage community, this murderer would have never been brought to justice. Join us as we chisel away at this violent, Alaskan horror story.-Resources to help:Support Alaska Native Peoplehttps://www.culturalsurvival.org/publications/cultural-survival-quarterly/alaska-native-tribal-rights-protection-plan?gad_source=1&gad_campaignid=1442219742&gbraid=0AAAAAD9zhqxMW2hHhcu2dRxsYl-OAAHtS&gclid=Cj0KCQiA1czLBhDhARIsAIEc7uiIhM2d0A90I9Q-W8Qut9wdrTNSauqMcUo8jjpsQGf5NzUkMoueqfIaAsEHEALw_wcB https://alaskatribes.org/additional-resources/ Domestic Violence - https://www.thehotline.org/ Call - 1.800.799.SAFE (7233)Text - START to 88788Suicide Prevention - https://sprc.org/ Call or Text: 988 Suicide and Crisis Lifeline--Follow us on Social Media and find out how to support A Scary State by clicking on our Link Tree: https://instabio.cc/4050223uxWQAl--Have a scary tale or listener story of your own? Send us an email to ascarystatepodcast@gmail.com! We can't wait to read it!--Thinking of starting a podcast? Thinking about using Buzzsprout for that? Well use our link to let Buzzsprout know we sent you and get a $20 Amazon gift card if you sign up for a paid plan!https://www.buzzsprout.com/?referrer_id=1722892--Works cited!https://docs.google.com/document/d/1Dq_0tJvFgEFuU1ZpZQ3E_LcuLc-RrTML8fSt9ILWb6k/edit?usp=sharing --Intro and outro music thanks to Kevin MacLeod. You can visit his site here: http://incompetech.com/. Which is where we found our music!
Brigadistas mexicanos apoyan control de incendios en ChileProtestan en CDMX por devolución de animales del Refugio FranciscanoMás información en nuestro Podcast
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Welcome to season 7 Ep: 268 of Hangin with Da Boys PodcastThank you for Hangin with Da Boys!Happy New Year! "yes" we know, we are a couple weeks late, but the damn Flu almost sent Jorge to the Shadow Realm! But we are back in action and looking forward to having some fun episodes and also some really cool guest on for 2026! Make sure you tune in and tell a friend! If you like what you hear, please consider (Rate/Subscribe/Favorite/Share) and please tell a FRIEND!Also check us out on our social platforms:YouTube @DaBoysPodTwitter , TikTok , Instagram - @DaBoys_Podand our website www.DaboysPod.com
We delve into the recent surge of Influenza cases across large swaths of the United States in recent weeks. This year is shaping up to be a particularly difficult year for health care facilities and the patients who need them for treatment. Dr. Joe Holley joins us today to discuss what he’s seeing in the Memphis, Tennessee area and what the national flu outlook is. The most common Influenza A strain right now is causing a surge in ER visits and hospital admissions across the U.S. right now. The dominant Influenza A strain for the 2025-2026 flu season is the A(H3N2) subclade K, a variant with notable mutations. The annual vaccine is moderately effective at preventing severe illness and hospitalization and the subclade K variant responds well to antivirals such as Tamiflu. The episode was co-hosted by Sam Bradley and Jamie Davis. Scroll down for Podcast Discussion Summary Thank you as always to Paragon Medical Education Group for their long-term support of the Disaster Podcast. Dr. Joe Holley and the team at Paragon continue to provide excellent and customized disaster response training to jurisdictions around the U.S. and internationally as well. Podcast Discussion Summary Flu Trends and Vaccination Impact Joe and Jamie discussed the recent surge in flu cases, particularly affecting unvaccinated individuals and those with underlying health conditions. Jamie shared his experience of being admitted to the ER with influenza A and noted that vaccinated individuals were more likely to be discharged. Joe confirmed that national trends showed higher hospitalization rates and deaths among the unvaccinated, elderly, and those with other medical issues. Flu Awareness for Healthcare Jamie shared his severe flu experience, which included a high fever, chills, and muscle cramps, leading him to seek emergency care. He emphasized the importance of flu awareness for healthcare professionals, noting the recent increase in flu-related deaths and pediatric deaths reported by the CDC. Healthcare Virus Transmission Prevention Jamie and Joe discussed protective measures for healthcare providers against virus transmission, emphasizing hand hygiene, respiratory protection, and avoiding confined spaces with sick individuals. Joe highlighted the risk of virus spread in confined environments like airplanes, while Jamie shared personal experiences and encouraged listeners to take transmission prevention seriously, noting its impact on their community. Post-COVID Brain Fog Symptoms Jamie described experiencing “brain fog” after recovering from COVID-19, which made mental tasks difficult and required significant mental effort. Joe explained that this could be due to increased inflammatory markers and the body’s energy expenditure in fighting the infection. Sam noted that their household member who had not been vaccinated experienced different symptoms, and both Sam and their household member took about two weeks to regain their energy levels. Influenza Symptoms and Management Joe explained that vaccination can reduce the severity of symptoms, and both Jamie and Sam experienced typical symptoms of influenza A, with Jamie noting the importance of IV fluids in managing his symptoms. Sam described severe gastrointestinal symptoms, while Jamie mentioned being prescribed Zofran despite not experiencing nausea. Joe elaborated on how dehydration and inflammatory mediators contribute to symptoms, and rehydration can help alleviate them. Winter Virus and Flu Updates Jamie shared his experience of being delayed for release from the hospital due to low blood pressure, which was unusual for him. The medical team tried various methods to increase his blood pressure, including making him angry and having him walk around. Joe explained that while having the flu is unpleasant, it leads to the development of protective antibodies. Sam noted that the flu often overshadows other winter viruses, and Joe confirmed they are still seeing a variety of other respiratory infections. Early Flu Treatment and Testing Joe and Sam discussed the importance of seeking medical attention and testing for flu symptoms, with Joe recommending early treatment with antiviral drugs like Tamiflu, which are most effective within the first 48 hours of symptoms. Sam acknowledged that healthcare professionals might be reluctant to visit doctors when they need to, possibly due to a false sense of invincibility. Jamie emphasized the significance of early testing and treatment for flu, aligning with Joe’s advice. Influenza Testing and Treatment Discussion The group discussed influenza prevention and treatment, with Joe emphasizing the importance of early diagnosis and medication, particularly given the availability of over-the-counter rapid flu tests. Jamie noted that the COVID-19 pandemic had increased access to home testing, which Sam and Joe hadn’t previously considered. They agreed that while many people might choose to tough it out, getting tested early could be beneficial. Flu Prevention and Training Updates The team discussed the flu, including its incubation period and how it spreads. Joe explained that people are most infectious when symptoms start, as their viral load is high. Jamie mentioned that the team had been affected by the flu in various ways. Joe also shared that Paragon is working on a new cadaveric-based simulator for pericardial tamponade training. The team encouraged listeners to stay safe and follow guidelines to prevent the spread of the flu. The group discussed the role of specialized training, with Jamie highlighting the sponsorship of the Disaster Podcast by Paragon Medical Education Group. Catch the full episode using the player above or on your favorite podcast platform, and don't forget to subscribe to the Disaster Podcast for weekly insights from leaders in disaster response and research!
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr's announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which eviscerate these changes, then deep dives into recent statistics on the measles epidemic- in particular in South Carolina, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, estimated societal burden of COVID-19 illness, deaths and hospitalizations, benefit of maternal COVID-19 vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, neurodevelopmental consequences of in-utero SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode 7 great Danish cheeses you should know (Cheese Professor) Norovirus in on the rise! (WasterWater Scan) Maternal Vaccine Receipt and Infant Hospital and Emergency Visits for Influenza and Pertussis (JAMA Open) TUESDAY MEASLES UPDATE: DPH Reports 124 New Measles Cases in Upstate, New Public Exposures, and Upcoming Vaccination Opportunities (South Carolina: Department of Public Health-they have one?) Measles cases soar in South Carolina, top 400 (CIDRAP) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) North Dakota confirms pediatric flu deaths as some states note surge in flu activity (CIDRAP) OPTION 2: XOFLUZA $50 Cash Pay Option (Xofluza) The Best Flu Drug Americans Aren't Taking (The Atlantic) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) Impact of universal nirsevimab prophylaxis in infants on hospital and primary care outcomes across two respiratory syncytial virus seasons in Galicia, Spain (NIRSE-GAL): a population-based prospective observational study (Lancet: Infectious Diseases) Interim Safety of RSVpreF Vaccination During Pregnancy (JAMA) Pfizer's RSV vaccine safe to use during pregnancy, study suggests (CIDRAP) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Evaluating the Effectiveness of 2024–2025 Seasonal mRNA-1273 Vaccination Against COVID-19-Related Hospitalizations and Medically Attended COVID-19 Among Adults Aged ≥ 18 years in the United States: An Observational Matched Cohort Study (Infectious Diseases and Therapy) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) Use of corticosteroids in influenza-associated acute respiratory distress syndrome and severe pneumonia: a systemic review and meta-analysis(Scientific Reports) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Incidence and Severity of Postacute Sequelae of SARS-CoV-2 Infection in the Omicron Era: A Prospective Cohort Study (JID) Reaching out to US house representative Letters read on TWiV 1288 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
Broadcast from KSQD, Santa Cruz on 1-15-2026: An emailer from Switzerland asks about fluorescein angiography requested before her first retina appointment. Dr. Dawn suspects protocol-based medicine screening for macular degeneration and suggests negotiating to see the doctor first given her different reason for seeing a retinal specialist. She encourages patients to maintain agency in medical settings. An emailer asks about creatine supplements. Dr. Dawn notes it helps muscle development in people doing weight training at 3-5 grams daily, but does nothing for aerobic-only exercisers. Claims about cognition and mood lack solid research. She advises against high-dose "loading," and cautions that creatine causes fluid retention problematic for congestive heart failure and should be avoided with stage 3 or higher kidney disease. Dr. Dawn reminds listeners it's not too late for flu shots, noting this season's H3N2 strain emerged after vaccine formulation was finalized. She laments mRNA vaccine research defunding, as that technology allows rapid reformulation. She describes organoids—tissues grown from stem cells that self-organize into primitive organ structures, enabling rapid drug screening without animal testing. Stanford researchers created assembloids by placing four neurological organoids together that spontaneously connected and built the ascending sensory pain pathway, offering new approaches to studying chronic pain. Dr. Dawn explains research showing satellite glial cells transfer healthy mitochondria to spinal sensory neurons through tunneling nanotubules. When this transfer fails, neurons fire erratically causing pain. Infusing healthy mitochondria into mouse spinal columns cured peripheral neuropathy—suggesting future periodic infusion treatments for humans. She reports Texas A&M researchers created "nanoflowers" from molybdenum disulfate that double stem cell's mitochondrial production, potentially supercharging regenerative medicine for conditions including Alzheimer's and muscular dystrophy. A caller asks about flu vaccines with egg allergy. Dr. Dawn explains that his gastrointestinal reactions to eggs differ from dangerous IgE allergies causing hives or anaphylaxis—GI intolerance doesn't preclude vaccination. Dr. Dawn reveals that 20 years of Parkinson's research followed a false lead. MRI showed increased iron in patients' brains, prompting iron chelation trials—which worsened symptoms. The problem: MRI detects paramagnetic ferric iron (stored, inert) not ferrous iron (biologically active). Patients accumulate useless ferric iron but are deficient in usable ferrous iron. Earlier 1980s studies showing that iron supplementation helped were ignored and abandoned prematurely. She suggests Parkinson's patients discuss iron supplementation with neurologists. She will post the link in the resources page on her website. A caller concerned about early Parkinson's describes tremors and balance problems in darkness. Dr. Dawn suggests darkness-related symptoms sound more like peripheral neuropathy than Parkinson's, recommending neurological examination and screening for diabetes, B vitamin deficiency, or heavy metal exposure. She confirms that sedentary lifestyle reduces mitochondrial production while progressive exercise builds both muscle and mitochondria.
We're stepping out of our Medicine on the Go series for a rapid-response episode on something hitting all of us hard right now: **influenza**. A lively debate among our colleagues sparked this conversation—especially around a newer flu antiviral, baloxavir (Xofluza). Who's using it? When does it make sense? How much does it cost patients? And how does it really compare to the longtime staple oseltamivir (Tamiflu)? The questions came fast, the opinions were strong, and we knew it was time to dig in. With flu season in full swing, this episode is all about practical decision-making at the bedside. Back to Basics: How Flu Antivirals Work To help break it all down, we welcome back our trusted ED pharmacist, Haley Burhans. We begin with a quick review of how influenza antivirals have evolved. , approved in 1999, was the first widely used antiviral and works by blocking the neuraminidase enzyme. Over time, concerns about resistance led to the development of newer options. That brings us to baloxavir (Xofluza), approved in 2018. Xofluza works differently by stopping viral replication earlier in the virus life cycle. While both medications aim to shorten illness and reduce complications, they differ in how they work, how they are dosed, and which patients benefit most. Who Should Get What—and When? Next, we focus on real-world ED decision-making. Who should receive Tamiflu, and who is a good candidate for Xofluza? We review use in children, pregnant patients, hospitalized patients with severe or worsening illness, immunocompromised patients, and those at higher risk due to conditions like asthma, lung disease, diabetes, heart disease, obesity, or older age. Timing is critical. Both medications work best when started within 48 hours of symptom onset. However, oseltamivir is still recommended even after that window for patients who are hospitalized or severely ill. We also discuss when antivirals can be used for post-exposure prpphylaxis. What Does the Evidence Say? We then take a closer look at the data behind antiviral treatment. Both Tamiflu and Xofluza shorten the time to symptom improvement. Observational studies suggest oseltamivir may reduce hospital length of stay and in-hospital death in adults and shorten hospital stays in children. Trial data also suggest baloxavir may be more effective against influenza B. We compare dosing strategies—five days of twice-daily Tamiflu versus a single-dose Xofluza—and review side effects and pediatric considerations. Real-World Barriers: Access and Cost Finally, we tackle the practical issues clinicians face every day. Tamiflu is widely available and familiar to most providers. Xofluza, on the other hand, often requires prior authorization and may be harder for patients to obtain. We discuss insurance barriers, out-of-pocket costs, manufacturer coupons, and situations where Xofluza may or may not be a realistic option. Take-Home Message This episode is a practical, evidence-based conversation designed to help emergency clinicians make confident decisions during flu season. Whether you're treating a high-risk patient, considering a single-dose option for uncomplicated flu, or simply trying to stay current, this discussion delivers clear, useful guidance you can use on your next shift! What's your go to flu treatment? What other medications would you like to learn more about? Hit us up on social media @empulsepodcast or at ucdavisem.com Hosts: Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis Guests: Haley Burhans, PharmD, Emergency Medicine Clinical Pharmacist at UC Davis Resources: CDC: Influenza Antiviral Medications: Summary for Clinicians AAP: Recommendations for Prevention and Control of Influenza in Children, 2025–2026: Policy Statement ACEP Influenza Resources and Updates **** Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
As 2026 begins, Contagion Podcast reflects on 2025, a year that tested global public health systems and reshaped how we think about infectious diseases, trust, and preparedness. In this special year in review episode, hosts Jackie Sherbuk and Vivian Vega examine the most consequential infectious disease and public health stories of the year—placing outbreaks, policy decisions, and scientific breakthroughs into clear clinical and societal context.The episode begins by confronting one of the defining challenges of 2025: erosion of public trust in public health institutions amid leadership upheaval, funding cuts, and widespread misinformation. Against this backdrop, long-controlled diseases returned with force. Measles resurged across the United States and Europe, threatening elimination status and exposing the consequences of falling vaccination coverage. Influenza surged early and intensely, straining hospitals and disproportionately impacting children and older adults. Other vaccine-preventable diseases—including pertussis and polio—reemerged, reminding listeners that immunity gaps anywhere can place everyone at risk.Beyond vaccines, the hosts explore global crises such as widespread cholera outbreaks driven by conflict, displacement, and climate-related flooding; ongoing tuberculosis transmission, including a major U.S. outbreak; and the expanding geographic reach of mosquito-borne diseases like dengue, chikungunya, and West Nile virus. They also discuss how viral hemorrhagic fever outbreaks, while limited in case numbers, continue to stress-test public health response systems worldwide.Importantly, the episode closes on hope. Breakthroughs such as twice-yearly lenacapavir for HIV prevention represent a paradigm shift in prevention and equity. Historic progress toward eliminating mother-to-child transmission of HIV, syphilis, and hepatitis B demonstrates what sustained investment and coordinated care can achieve. Above all, the hosts honor the resilience and dedication of healthcare and public-health professionals who continue to protect communities amid uncertainty.This episode offers a thoughtful, candid look at 2025—and a reminder that preparedness, communication, and trust remain our most powerful tools.Dr. Vega would like to thank her friend Job Meiller for his musical contributions, "One," and "Imagine," to our major segment breaks. Thank you, Job!Thanks also to Dr. Ana Velez, our artistic contributor, for her artwork utilized in our episode thumbnails.
Mega centro de vacunación de la UNAM, ejemplo nacionalChoque múltiple colapsa la México-PachucaEntregan cobijas casa por casa en Amecameca Más información en nuestro Podcast
Listen to this podcast featuring highlights from our expert roundtable discussion to learn about the most pressing issues in pediatric influenza vaccines, including current vaccine technologies, recent vaccine uptake and epidemiologic trends, and how to discuss the vast benefits of timely vaccination in pediatric patients with their parents and caregivers. Topics covered include:Groups at High Risk for ComplicationsGuideline Recommendations for Influenza VaccinationAvailable Seasonal Flu Vaccine Formulations and Their CharacteristicsPractical Considerations for Selecting Pediatric Influenza VaccinesUptake of Influenza Vaccines in Children: Reversing the TrendsPresenters:Ravi Jhaveri, MD, FIDSA, FPIDS, FAAPDivision HeadPediatric Infectious DiseasesAnn & Robert H. Lurie Children's Hospital of ChicagoProfessor of PediatricsNorthwestern University Feinberg School of MedicineChicago, IllinoisTina Q. Tan, MD, FAAP, FIDSA, FPIDSProfessor of PediatricsFeinberg School of Medicine of Northwestern UniversityPediatric Infectious Diseases AttendingMedical Director, International Adoptee ClinicPresident, Lurie Medical/Dental StaffAnn & Robert H. Lurie Children's Hospital of ChicagoChicago, IllinoisJennifer M. Walsh, DNP, CPNP-PC, CNECertified Pediatric Nurse Practitioner, Primary CareAssistant ProfessorGeorge Washington UniversitySchool of NursingWashington, DCLink to full program: https://bit.ly/45UVzy6Get access to all of our new episodes by subscribing to the Decera Clinical Education Infectious Diseases Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Influenza usually starts in November, and cases increase throughout the winter, not fading until March or so. This year's flu season is especially severe. An awful lot of people are suffering with fever, cough, congestion, body aches, headaches and other symptoms of influenza. Of course, flu is not the only infection out there. Other viruses […]
Marty , Kristine and Patrick speak with Dr. Wong about the Flu
Discussed in this episode: Influenza levels are rising quickly This year's flu vaccine appears to be reducing the risk of hospitalization in adults by 30-40%. That's a significant help, but a worse topline than in prior flu seasons. This is likely because the Influenza A subclade K, which has come to predominate, emerged too late to be specifically targeted by this year's vaccine. The implications of RFK Jr's CDC drastically changing the childhood vaccination schedule (which it had not done by airtime, but did announce before we published the podcast). To send us a question in advance of next week's show, write to: coronacalls@kpfa.org Tune in live Monday mornings at 7:30am Pacific at kpfa.org. Podcast music credit: Now Son by Podington Bear, licensed under a Attribution-NonCommercial 3.0 International License. The post Corona Calls for 01.05.2026 appeared first on KPFA.
It comes every year - but what's to blame for this year's influenza season severity?Several strains are circulating across Canada, with healthcare professionals scrambling to treat one of the leading causes of death in this country. And with the U.S.'s upcoming withdrawal from the World Health Organization later this month, virus and vaccine-related research will soon become scarce for the countries who depend on the data - including Canada.Host Nima Rajan speaks to Dr. Joss Reimer, former President of the Canadian Medical Association and former Chief Medical Officer for the Winnipeg Regional Health Authority. The two discuss how Canada's healthcare system needs to diversify its science research partners, and what Canadians can do in the short-term to help protect themselves and others. We love feedback at The Big Story, as well as suggestions for future episodes. You can find us:Through email at hello@thebigstorypodcast.ca Or @thebigstoryfpn on Twitter
Influenza is rising rapidly across the U.S., and headlines about H3N2 and “new variants” are everywhere. In this episode, I break down what the data actually show, what's driving this flu season, what H3N2 subclade K really means, how well the flu shot is holding up (spoiler- it's doing fine!), and what matters most for protecting your family. Using current CDC surveillance data and real-world vaccine effectiveness, we put this season into clear perspective. I also share how our household is thinking about and managing play dates, preschool and traveling during an active flu season. Citations:Seasonal Flu Vaccine Basics | Influenza (Flu) | CDCInfluenza (Flu) | Influenza (Flu) | CDChttps://www.cdc.gov/flu/php/surveillance/in-season-severity.htmlhttps://www.cdc.gov/flu/hcp/clinical-signs/index.htmlhttps://www.cdc.gov/flu/about/coldflu.htmlUnderstanding Influenza Viruses | Influenza (Flu) | CDCLegal: This podcast is for informational and educational purposes only and does not constitute medical advice. The content reflects general public health information and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare professional with any questions regarding a medical condition or health decisions.
SSC CDMX invita a niños a dejar su carta a los Reyes Magos Localizan sin vida al presidente de Grupo Corona Incendio deja sin electricidad a miles de hogares en BerlínMás información en nuestro podcast
Sick, stuffed with Christmas chaos, and running on fumes—but Eric and Kiley still show up. The final podcast of 2025 delivers the long-promised mystery date reveal, a few apologies, and a bold promise: 2026 is going to be one for the books.
High-Dose Influenza Vaccine Effectiveness against Hospitalization in Older Adults
«Triptofanito y Lisina están a punto de librar la batalla más peligrosa de toda su vida. El maravilloso Reino del Cuerpo Humano, donde habitan, se ve amenazado por un enemigo desconocido: llegó una nueva enfermedad respiratoria que ha sido noticia no sólo en los condados del Cuerpo sino en el mundo entero. Nuestros amigos no pierden un momento y convocan a un congreso presidido por la sabia neurona C-MAN-TI-K, quien, junto a sus colegas, 100-TIFI-K y A-B-DIS descifran la identidad del invasor: el virus de la Influenza. Así comienza la travesía de los pequeños viajeros que han llevado a más de tres generaciones de lectores a recorridos fantásticos e inolvidables, primero por el cuerpo humano y luego por la célula para, en esta ocasión, derrotar a un villano que parece invencible.» Con eso resumen los editores de la Editorial Joaquín Mortiz del Grupo Planeta el libro escrito por el renombrado médico cirujano Julio Frenk y su coautor Andrés García Barrios, titulado Triptofanito y la batalla contra la influenza. El doctor Pablo Kuri Morales, experto en epidemiología y salud pública, recomienda el libro mediante esta breve reseña: «De manera ágil y entretenida, pero precisa y clara, y en ocasiones magistral, nos explica los procesos de la enfermedad, alcanzando tantos detalles como no es usual encontrar en libros de divulgación científica.»1 Por su parte, el doctor Adolfo Martínez Palomo comenta: «La persona (niño, adolescente o adulto) que lea Triptofanito y la batalla contra la influenza no sólo pasará un rato agradable, sino, sobre todo, aprenderá los conceptos fundamentales sobre el virus de la influenza, su modo de transmisión, las formas de reducir el contagio y el valor del tratamiento con antivirales y vacunas.»2 El penúltimo párrafo es un buen ejemplo del espíritu del libro: «El peligro no había terminado.... El Virus de la Influenza seguía ahí afuera, en otros cuerpos humanos, quizás en muchos barandales, perillas de puertas, libros..., mutando una y otra vez.... Era necesario tener cuidado, seguir cumpliendo las medidas de higiene, acordarse de lavarse las manos, no saludar de mano y beso, no acudir a trabajar enfermo...»3 El año después de la publicación de este tercer libro de la serie de Triptofanito, en una entrevista el doctor Frenk explicó que había escrito el primero a los diecinueve años de edad, cuando aún era estudiante de la Facultad de Medicina de la Universidad Nacional Autónoma de México. El curso de fisiología lo había motivado a explicarles a los jóvenes el funcionamiento del cuerpo en forma de novela. Para su sorpresa y gran satisfacción, aún después de más de treinta años estudiantes de medicina le comentaban que la lectura de Triptofanito los había impulsado a definirse por esa vocación.4 Quiera Dios que, con la misma pasión que movió al doctor Frenk a dedicarse a la misión permanente de mejorar la salud y el bienestar de personas alrededor del mundo,5 también nosotros, al igual que Juan el apóstol, oremos por nuestros hermanos en todo el mundo para que disfruten de buena salud tanto física como espiritual.6 Carlos ReyUn Mensaje a la Concienciawww.conciencia.net 1 Andrés García Barrios y Julio Frenk, Triptofanito y la batalla contra la influenza (Ciudad de México: Editorial Planeta Mexicana, bajo el sello editorial Joaquín Mortiz, 2009) En línea 2 abril 2020. 2 Adolfo Martínez Palomo, «Triptofanito y la batalla contra la influenza», 26 agosto 2009 En línea 2 abril 2020. 3 Ibíd. 4 Mario de la Piedra Matute, «Entrevista al Dr. Julio Frenk», AAPAUNAM: Academia, Ciencia y Cultura, 28 mayo 2010, p. 153 En línea 2 abril 2020. 5 «President Julio Frenk: Biografía», Office of the President, University of Miami En línea 3 abril 2020. 6 3Jn 2
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En el episodio de hoy martes 23 de Diciembre Sergio Fajardo reafirmó que no hará alianzas con sectores extremos ni con quienes promuevan discursos de odio, como Abelardo de la Espriella, y aseguró que su campaña busca construir una nueva mayoría política de cara a las elecciones de 2026, basada en el respeto y los principios democráticos Por otro lado, el Ministerio de Salud confirmó el primer caso en Colombia de la variante K de la influenza A (H3N2), importado desde Estados Unidos, y señaló que no hay un aumento grave de casos y que la vacunación continúa disponible
NotiMundo A La Carta - Cristina Jácome, Vacunación contra la influenza en el país by FM Mundo 98.1
1. Premio del Powerball alcanza los $1,700 millones para el sorteo deNochebuena2. Salud sobre el drástico aumento en casos de influenza: "Se va atener que declarar una epidemia”3. Consumo de las familias: se triplican los gastos médicos4. Piden a la ONU que interceda para detener prácticas militares en PR. Líderescívicos, religiosos y de organizaciones políticas le escribieron al secretariogeneral de la ONU Antonio Guterres y al Comité de Descolonización queintercedan5. Asaltos anfibios y ataques con bombas: a flote ejercicios en Ponce ySalinas6. No se pueden anexar otros países, dicen líderes daneses y groenlandesesa Trump7. "No solo Venezuela": Trump sobre los planes de lanzar ataquesterrestres en América Latina8. Panamá dice que petrolero interceptado cerca de Venezuela no respetónormas marítimas 9. Tailandia y Camboya vuelven a la mesa de paz, tras la fracasada treguade TrumpEste es un programa independiente y sindicalizado. Esto significa que este programa se produce de manera independiente, pero se transmite de manera sindicalizada, o sea, por las emisoras y cadenas de radio que son más fuertes en sus respectivas regiones. También se transmite por sus plataformas digitales, aplicaciones para dispositivos móviles y redes sociales. Estas emisoras de radio son:1. Cadena WIAC - WYAC 930 AM Cabo Rojo- Mayagüez2. Cadena WIAC – WISA 1390 AM Isabela3. Cadena WIAC – WIAC 740 AM Área norte y zona metropolitana4. WLRP 1460 AM Radio Raíces La voz del Pepino en San Sebastián5. X61 – 610 AM en Patillas6. X61 – 94.3 FM Patillas y todo el sureste7. WPAB 550 AM - Ponce8. ECO 93.1 FM – En todo Puerto Rico9. WOQI 1020 AM – Radio Casa Pueblo desde Adjuntas 10. Mundo Latino PR.com, la emisora web de música tropical y comentario Una vez sale del aire, el programa queda grabado y está disponible en las plataformas de podcasts tales como Spotify, Soundcloud, Apple Podcasts, Google Podcasts y otras plataformas https://anchor.fm/sandrarodriguezcotto También nos pueden seguir en:REDES SOCIALES: Facebook, X (Twitter), Instagram, Threads, LinkedIn, Tumblr, TikTok BLOG: En Blanco y Negro con Sandra http://enblancoynegromedia.blogspot.com SUSCRIPCIÓN: Substack, plataforma de suscripción de prensa independientehttps://substack.com/@sandrarodriguezcotto OTROS MEDIOS DIGITALES: ¡Ey! Boricua, Revista Seguros. Revista Crónicas y otrosEstas son algunas de las noticias que tenemos hoy En Blanco y Negro con Sandra.
Europe's influenza season has arrived earlier than expected this year, raising concerns about pressure on health systems as respiratory illnesses circulate during the winter months. While the surge has prompted questions about vaccine effectiveness and vulnerable groups, health experts say the situation remains manageable – if people take the right precautions.Speaking with UN News's Vibhu Mishra, Marc-Alain Widdowson, who leads pandemic threat and communicable disease work at the World Health Organization's European Regional Office, explains what's driving this year's flu season, who is most at risk, and why it's still not too late to get vaccinated.
00:00 Intro01:14 H3N2 Influenza Virus Surges in China, Death Toll Rises03:32 China Reports Before WHO, Hides Key Information04:56 Trump Signs 2026 NDAA Defense Bill05:35 NDAA Plans to Publicize Top CCP Leaders' Wealth06:13 NDAA Removes China From DOD Supply Chain07:35 DHS Withdraws Request to Deport Guan Heng08:10 Japan Reiterates Stance on Procuring Nuclear Weapons09:48 Fleming: Largest U.S. Arms Sale to Taiwan | Analysis10:47 CCP's Timeline on Taiwan: Why U.S. Action Is Urgent11:29 Before Bullets Fly: How China Wages War Without Fighting12':39 Communism Is a Religion': Fleming13:30 Cognitive Warfare Places Citizens on the Front Lines15:23 Fleming on His Book “Red Tsunami”: It's a Survival Guide15:58 TikTok Signs Deal to Sell to U.S. Investor Group17:05 Hong Kong Police Expand Dragnet on Overseas Activists
Fuerzas Especiales refuerza seguridad en Sinaloa: Sedena Detectan en Ecuador primer caso de influenza AH3N2 variante K ¿Sabes cuál es el símbolo nacional de Escocia? Aquí te decimos Más información en nuestro podcast
What is a call? How does a person know if God is calling them to mission service? Join in a discussion as these and other questions are addressed.
* Acusan a jefe criminal de manejar huachicol desde la cárcel* ¿Cómo es el nuevo tipo de influenza que ya llegó a México?* Le llueve a la FIFA por el precio de boletos del Mundial
Wildermuth, Volkart www.deutschlandfunk.de, Forschung aktuell
Fecke, Britta www.deutschlandfunk.de, Forschung aktuell
No te pierdas el evento “Artesanos en el Corazón” en la CDMX México se mantiene entre los principales exportadores de alimentos
Dr. Glenn Wortmann, Medical Director of Infection Prevention at the MedStar Institute of Quality and Safety, joins WAMU to discuss how to prepare for the upcoming flu season, which he and other medical experts warn will be a "tough one."
Low resource settings require much innovation and streamlining resources to meet set goals. With healthcare becoming more commercial and profit driven, missional healthcare in low resource settings faces many challenges. Sustainability is a big question with people finance , and equipment scarce and hard to come by. Missional models of healthcare often run into hurdles of sustainability, longevity and relevance even as healthcare slowly turns into business. In this setting of multifactorial challenges and increasing compliances how can missional healthcare be relevant and sustainable? Many saints of God have committed their lives to fulfil this great commission in some of the most underserved and unreached areas of the world. With the birth of Emmanuel Hospital Association (EHA) a different model of missional healthcare emerged in India. Over the last 55 years of its existence, EHA has shown that through all the challenges, this may be one of the ways to sustain missional healthcare in areas of need. With increasing divide between the rich and poor, overwhelmed government systems, a ruthless insurance system, and high end corporate healthcare, it is still possible for missional healthcare to provide low cost, high quality, technologically advanced care to people in need while remaining sustainable. We bring lessons from India and our experience with Emmanuel Hospital Association over the last 3 decades.
¡¡PODCAST!!Lic. Alicia Rábago… “El Síndrome del Niño Bueno” Wlises Mendoza… Pastorela: “La noche más venturosa” (20 años de llevar un mensaje de esperanza) Francisco Moreno… Influenza H3N2 (Súper Gripa) Dra. Tere Vale… “Día Internacional contra la Soledad No Deseada” Toño y Arturo Medina… “Los Chinacos de Toño Medina en el Lunario”
¡CDMX va contra la extorsión! Presentan plan con 15 acciones Alerta sanitaria en Perú por nueva variante de influenzaMás información en nuestro Podcast
Pemex invierte más de 200 mil millones de pesos en 2025 Tormenta invernal agrava crisis humanitaria en GazaLas Posadas: fe, tradición y herencia cultural mexicana Más información en nuestro podcast
Garantizan abasto de medicamentos para 2026: Ssa Bloquean carretera México 15 en SonoraHonduras denuncia “golpe” tras indulto a expresidenteMás información en nuestro podcast
Hoy en Me Lo Dijo Adela abrimos la conversación con Francisco Rivas, director del Observatorio Nacional Ciudadano, para contrastar los supuestos avances en seguridad que presume el gobierno con los datos reales frente a una violencia que no cede; además, la internacionalista Brenda Estefan analiza uno de los hechos más graves de las últimas horas, un ataque armado durante una celebración judía que dejó 16 personas muertas, sus implicaciones internacionales y el riesgo de normalizar el terror; el infectólogo Alejandro Macías enciende las alertas sobre el posible riesgo epidemiológico en México por AH1N1 y en Estados Unidos por H3N2, explicando qué tan preparados estamos, qué síntomas vigilar y qué errores no repetir; en foro, Alicia Moreno, promotora de lectura infantil, comparte recomendaciones de libros y películas para el invierno con opciones inteligentes para niñas, niños y familias; como todos los días, el Montón Shot con Juan Carlos Díaz Murrieta y Emilio Morales repasa lo que está dando de qué hablar, y cerramos con la sección Piel Sana junto a Javi Derma, dermatólogo oncólogo, quien explica todo lo que debemos saber sobre el cabello: cuidados, mitos, señales de alerta y cuándo sí acudir al especialista. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Identifica los síntomas clave de la influenza AH3N2 Decomisan 85 kilos de metanfetamina en Sonora; hay cinco detenidosOrión, la constelación que une mitos griegos, egipcios y latinoamericanosMás información en nuestro podcast
Visita sorpresa de Sheinbaum al IMSS en Juárez Reos de alta peligrosidad son trasladados fuera de MichoacánProtestas masivas en Brasil contra impunidad a BolsonaroMás información en nuestro Podcast
It's that time of the year when the weather gets cold and dreary, while we become less active and eat excessively for the holidays. But this is not a show about diets, healthcare, or the like. As the supposed "super flu" is spreading this month, there has become a growing disconnect between those who believe invisible particles cause disease and those who think there is no such thing as an invisible particle. But what if the truth were somewhere in the middle, and what if "what really makes you ill" is a complex yet very simple thing to understand? What if this understanding is not merely obscured by greed or ego, but instead a magical language accompanied by the ritualistic exorcisms we perform without a second thought? What if the modern concept of disease is based on an ancient superstition and literal demonology?*The is the FREE archive, which includes advertisements. If you want an ad-free experience, you can subscribe below.WEBSITEFREE ARCHIVE (w. ads)SUBSCRIPTION ARCHIVE-X / TWITTERFACEBOOKINSTAGRAMYOUTUBERUMBLE-BUY ME A COFFEECashApp: $rdgable PAYPAL: rdgable1991@gmail.comRyan's Books: https://thesecretteachings.info - EMAIL: rdgable@yahoo.com / rdgable1991@gmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-secret-teachings--5328407/support.
IN this episode, Dr's J and Santhosh cover stories, studies, and general knowledge in their annual influenza special. Along the way they cover the poor decision making of the secretary for health and human services, the confluence of influenza and journal clubs, the original identification and discovery of the flu virus, a sneezy ferret, optimistic media, military vaccine testing, the discovery of seasonal flu changes, the art of flu surveillance, the damage done to surveillance by this administration, alternative vaccine production methods, dosing change recommendations and more! so sit back and catch some knowledge about whats coming to town!Further Readinghttps://utppublishing.com/doi/10.3138/jammi-2025-0025https://www.cdc.gov/fluview/surveillance/2025-week-45.htmlhttps://www.nejm.org/doi/full/10.1056/NEJMoa2416779?query=featured_homehttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01742-8/abstracthttps://www.ijidonline.com/article/S1201-9712(25)00322-4/fulltextSupport Us spiritually, emotionally or financially here! or on ACAST+travelmedicinepodcast.comBlueSky/Mastodon/X/Instagram: @doctorjcomedy @toshyfroTikotok: DrjtoksmedicineGmail: travelmedicinepodcast@gmail.comSpotify: https://open.spotify.com/show/28uQe3cYGrTLhP6X0zyEhTPatreon: https://www.patreon.com/travelmedicinepodcast Hosted on Acast. See acast.com/privacy for more information.
Learn exactly how the flu makes you sick and how to interrupt each phase of infection. Discover the science-backed supplements that act as "fire extinguishers" for inflammation, why vitamin D and NAC are essential during flu season, and how to support your immune system before, during, and after viral infections to recover faster and stay healthier year-round. 5 KEY TAKEAWAYS The flu is a viral infection that never truly leaves your body – it can lay dormant and flare up during times of stress, making prevention and immune support crucial year-round, not just during illness. Vitamin D and NAC are your immune system's "fire extinguishers" – both reduce pro-inflammatory cytokines (like TNF-α and IL-6) that cause severe lung inflammation during flu infections, helping you recover faster and experience less severe symptoms. NAC does triple duty during flu season – it thins mucus for easier breathing, reduces inflammation in the lungs, and boosts glutathione production (your body's master antioxidant) to fight viral infections more effectively. Most people are deficient in the nutrients needed to fight flu – vitamin D deficiency affects most of the population, and low levels of glutathione, zinc, and selenium make you more vulnerable to severe viral infections and slower recovery. Viral infections deplete your adrenal glands – the constant stress response during and after flu infection tanks your HRV and DHEAS levels, requiring adrenal support to fully recover and prevent long-term fatigue or autoimmune-like symptoms. FEATURED PRODUCT The D - provides 5,000 IU of vitamin D3, which acts as a "fire extinguisher" for inflammatory cytokines released during viral infections, reducing lung inflammation and supporting your body's natural immune response. Find it here: https://mswnutrition.com/products/the-d TIMESTAMPS 00:00 – START 02:45 – Why the flu is a viral infection that never leaves your body 05:30 – How respiratory viruses spread and enter your system 08:15 – NAC: The game-changer for mucus, allergies, and lung inflammation 12:40 – Why vitamin D is your immune system's most powerful tool 16:20 – The science of inflammatory cytokines and how they damage your lungs 20:10 – Vitamin D studies: 10,000 IU protocol for flu prevention 24:35 – NAC and glutathione: Your body's master antioxidants explained 28:50 – Why people with fatty liver get sicker from viral infections 32:15 – Lysine, zinc, and selenium: Additional immune support nutrients 36:40 – The IV therapy protocol for sick patients in clinical practice 40:20 – Supporting your adrenal glands after flu infection 43:15 – HRV tracking and how to measure your body's stress response 46:00 – Product recommendations: The D, NAC+, Zen, and Gut Powder RESOURCES NAC Benefits for Health – https://www.drugs.com/medical-answers/nac-benefit-health-3573010/ Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths – https://pmc.ncbi.nlm.nih.gov/articles/PMC7231123/ Vitamin D and Respiratory Health – https://pmc.ncbi.nlm.nih.gov/articles/PMC4488782/ The Antioxidant Role of Non-Vitamin, Non-Mineral Micronutrients – https://pmc.ncbi.nlm.nih.gov/articles/PMC8234027/ N-Acetylcysteine and Respiratory Diseases – https://pmc.ncbi.nlm.nih.gov/articles/PMC11278452/ The Role of Zinc in Antiviral Immunity – https://pmc.ncbi.nlm.nih.gov/articles/PMC8349606/ Selenium Supplementation and Influenza Vaccine Response – https://brieflands.com/journals/jkums/articles/69746 Selenium and Viral Infections – https://pmc.ncbi.nlm.nih.gov/articles/PMC6769590/ Immune Activation and Autonomic Nervous System in Post-Viral Fatigue – https://pmc.ncbi.nlm.nih.gov/articles/PMC10795785/ Long COVID and Heart Rate Variability Study – https://www.cidrap.umn.edu/covid-19/long-covid-changes-heart-rate-variability-study-suggests CONNECT
On this episode of Vitality Radio, Jared dives into why so many people are experiencing stubborn, lingering colds and sinus issues this season—and why the usual immune routines aren't cutting it. He breaks down the overlooked connections between the gut, liver, and immune system, and explains how supporting these systems can help the body return to normal, quicker recovery patterns. You'll also hear practical immune strategies for adults, kids, and pregnant/nursing moms, plus a few of Jared's favorite tools for respiratory support, sinus comfort, and overall immune resilience. And of course, Jared announces this year's Immune 25 Sale, with savings up to 25% on a collection of his top immune-supporting formulas. Whether you're trying to stay well or finally shake something that keeps coming back, this episode offers a clear path forward.Immune25 Sale through 1/31/26! BUILD YOUR OWN STACK FROM THE IMMUNE25 COLLECTION!2 different items - extra 10% off3 different items - extra 15% off4 or more items - extra 25% off *Please be sure to choose at least 3 different products!Additional Information:#590: Get Well and Stay Well This Cold and Flu Season. Plus a Fraud Alert!#413: Common Misconceptions About Colloidal Silver and the Power of Topical Silver Gel with Keith Moeller#367: Your Silver User's Guide: Colloidal, Ionic, Nano…What Does It All Mean, Is It Safe, And Does It Work?Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
America Out Loud PULSE with Dr. Peter McCullough and Malcolm Out Loud – A new influenza strain, H3N2, rises overseas, and we wonder whether our public health system will warn us in time. The vaccine recipe was set months ago. Viruses do not respect that calendar. When a strain mutates after the shot, decisions are made, and protection drops. We do not deny scientific complexity. We demand clarity...