POPULARITY
HEALTH NEWS An apple cider vinegar drink a day? New study shows it might help weight loss Food Additive in Pizza, Pancakes Linked to Lower Sperm Counts Ramadan fasting may protect patients with heart problems, say researchers An investigation into the potential association between nutrition and Alzheimer's disease Breakthrough Discovery Shows That Resonant Frequencies Can Kill Cancer Cells Study finds interactions with dogs can increase brainwaves associated with stress relief and heightened concentration An apple cider vinegar drink a day? New study shows it might help weight loss Holy Spirit University of Kaslik (Lebanon), March 13, 2024 An experimental study, released today, looks into whether apple cider vinegar could be effective for weight loss, reduce blood glucose levels and reduce blood lipids (cholesterol and triglycerides). A double-blinded, randomized, clinical trial in a group of overweight and obese young people aged from 12–25 years suggest it could reduce all three—but it might not be as simple as downing an apple cider vinegar drink a day. The participants were instructed to consume either 5, 10 or 15ml of apple cider vinegar diluted into 250ml of water each morning before they ate anything for 12 weeks. A control group consumed an inactive drink (a placebo) made (from lactic acid added to water) to look and taste the same. After a period of three months apple cider vinegar consumption was linked with significant falls in body weight and body mass index (BMI). On average, those who drank apple cider vinegar during that period lost 6–8kg in weight and reduced their BMI by 2.7–3 points, depending on the dose. They also showed significant decreases in the waist and hip circumference. The authors also report significant decreases in levels of blood glucose, triglycerides, and cholesterol in the apple cider groups. While the study appears promising, there are also reasons for caution. The study participants were aged from 12 to 25, so we can't say whether the results could apply to everyone. Food Additive in Pizza, Pancakes Linked to Lower Sperm Counts University of Kentucky, March 11, 2024 An ingredient commonly found in many baked goods and processed foods — including school lunches — may cause oxidative stress, DNA damage and decreased testosterone levels and sperm counts in male mammals. Sodium aluminum phosphate is an additive used in food products as an emulsifying agent, leavening acid and stabilizer. It is a white, odorless solid slightly soluble in water. The widespread use of sodium aluminum phosphate in everyday food products and commercially baked goods such as cakes, muffins and biscuits, and self-rising flours and baking powders. It is also used in processed cheeses to improve texture and melting properties. A peer-reviewed scientific literature on aluminum reproductive toxicity by Robert A. Yokel, Ph.D., published in Critical Reviews in Toxicology found aluminum exposure can lead to adverse reproductive outcomes in male and female mammals. Yokel's analysis revealed that “male reproductive endpoints were significantly affected after exposure to lower levels of Al [aluminum] than females.” In both male and female mice and rats, increased aluminum intake resulted in higher concentrations of the metal in the fetus, placenta and testes. Ramadan fasting may protect patients with heart problems, say researchers University of Sharjah (United Arab Emirates) & University of Utah, March 13, 2024 Those observing Ramadan may have their cholesterol, other lipids, and inflammatory markers in their blood reduced. This is the conclusion of a group of scientists examining the model of Ramadan Intermittent Fasting (RIF) in overweight and obese people. "RIF is associated with improvements in plasma sphingosine, sphinganine sphingomyelin, and dihydrosphingomyelin lipid species," the scientists write in their study published in Scientific Reports. RIF is a special type of intermittent fasting during which fasting Muslims refrain from eating, drinking (including water), smoking, or engaging in sexual activities from pre-dawn to sunset. The fasting duration differs depending on geographical location, but it is generally estimated to last between 12-17 hours a day. The daily average fasting duration for Muslims worldwide is reported to be approximately 15 hours per day, depending on location. An investigation into the potential association between nutrition and Alzheimer's disease Capital Medical University (China) (Frontiers) Malnutrition is the most common nutritional issue in Alzheimer's disease (AD) patients, but there is still a lack of a comprehensive evaluation of the nutritional status in AD patients. This study aimed to determine the potential association of various nutritional indices with AD at different stages. Lower levels of total protein, albumin, globulin, and apolipoprotein A1 were associated with AD (all p
We're very happy to welcome back Dr. Dan Levi to the AMBOSS Podcast! Since our last interview with him, he has switched from working as a physician in Germany to become a trainee in family medicine in the UK! Since he scored in the top 15 percentiles of the USMLE Step 1, Step 2, and the MSRA in the UK, he shared some of his study secrets with us plus his advice about mentoring and life as a doctor. Fun Fact: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0272460 https://pubmed.ncbi.nlm.nih.gov/21211793/ https://www.nature.com/articles/nrn2298 https://pubmed.ncbi.nlm.nih.gov/21417955/ https://pubmed.ncbi.nlm.nih.gov/22213750/ Sign up for a free 5-day trial at https://go.amboss.com/pod-5day-trial. Read more at the AMBOSS blog: https://go.amboss.com/blog-ambosspod. Find out more about the AMBOSS podcast: https://go.amboss.com/int_podcast-23.
This month we speak to Dr David Little who is a Consultant Radiologist and Head of School of Severn Radiology. We delve into the MAP debate and discuss the open letter he wrote to the RCR about PA regulation in October which gained over 1200 signatures. He also tells us what it was like running for RCR President in 2002 and we get his perspective on Radiology recruitment as a member of the RCR recruitment subcommittee including his strong views on the MSRA and top tips for anyone applying this year.
Intel quiere comprar parte de Arm / Coche autónomo se mete en un tiroteo / El juicio de GitHub Copilot se calienta / Acuerdo PLD Space y Arianespace Patrocinador: Hasta el 30 de junio, en las estaciones de servicio de BP puedes conseguir un ahorro de hasta 8 céntimos por litro simplemente repostando BP Ultimate con tecnología Active. Descárgate la app Mi BP para tu Android o iPhone. — Date prisa, que se acaba el 30 de junio. Intel quiere comprar parte de Arm / Coche autónomo se mete en un tiroteo / El juicio de GitHub Copilot se calienta / Acuerdo PLD Space y Arianespace
今天又是一期关于AI的硬核讨论!这次依旧是 AI 领域的核心话题之一:GPT 是否能带领我们通向 AGI (Artificial General Intelligence, 通用人工智能)?如何评估和理解 AI 的能力?大模型范式下,我们如何定义智能?这些问题,至今没有标准的答案。大模型加上 HuggingGPT, AutoGPT 一系列 generative agents(生成式代理) 之后,给各个行业甚至整个社会带来什么改变?我们这期的嘉宾,来自中美学术界与产业界,绝对难得的一线视角。 Hello World, who is OnBoard!? GPT 之后,我们关于AGI 的探讨又更近了一个阶段。但如果走向通用人工智能时代是一个大概率事件,那么实现通用人工智能的最佳路径只有 GPT 吗?还有哪些值得大家去探索的方向有待讨论,探索的方法论又从何而来?这是 OnBoard! 与科技早知道又一期合作节目,我和大家都非常喜欢的硅谷徐老师,与来自微软研究院两篇刷屏论文的作者,以及中国AI独角兽研发总监一起,深度探讨最值得你关心的几个AI领域核心命题。相信你听完这一期,会对人工智能的能与不能,希望与挑战,有不一样的认识。 长达3小时的谈话,即使知道短一些的版本会更容易传播,但是Monica 还让大家听到更多原汁原味的讨论,所以尽量保留了更多内容。相信这些干货,值得你的时间。Enjoy! 嘉宾介绍 硅谷徐老师,硅谷连续创业者、人工智能高管、斯坦福商学院客座讲师,「科技早知道」主播 |推特:@H0wieXu| 微信公众号:硅谷云| AI博客:howiexu.substack.com 谭旭,微软亚洲研究院 高级研究员,主要研究方向为生成式人工智能及其在语言/语音/音乐生成中的应用,《MSRA researcher, HuggingGPT》作者之一 张弋,微软亚洲研究院 高级研究员,主要研究方向为通用人工智能的物理、数学,《Microsoft researcher,Sparks of AGI》 论文作者之一 红博士,某 AI 公司研发总监,研究方向:计算机视觉、数据压缩、通用人工智能。公众号:红博士说 主持: Monica,美元VC投资人,前 AWS 硅谷团队+AI创业公司打工人,公众号:M小姐研习录 (ID: MissMStudy) 主理人 | 即刻:莫妮卡同学 我们都聊了什么 [01:41] 嘉宾自我介绍,最近关注的AI研究(及Monica的隐藏小Update!) [07:48] 第一视角解读微软刷屏论文:Sparks of Artificial General Intelligence: Early experiments with GPT-4 [13:25] GPT4 是 AGI 吗? [18:42] 对于这篇AGI论文常见的误解:为什么这是比公开 GPT4更强的模型? [21:48] 为什么GPT4 没有视觉训练数据,却能够理解图片? [26:46] GPT4 达到高中生水平了吗?为什么能比 ChatGPT 提高这么多? [31:26] 大模型的 Hallucination(幻觉)要如何解决?业界有哪些尝试? [44:59] 大模型要实现AGI,还有哪些挑战?为什么“思考太快了”是一种局限? [56:57] 火爆全网的 HuggingGPT: 研究背景、运作机制、与 AutoGPT 和 ChatGPT Plugin 的异同? [65:30] 我们需要不同领域的 foundation model (基础模型)吗? [72:27] HuggingGPT 和 AutoGPT 技术成熟了吗?为什么需要专家生态? [78:05] 为什么说 ChatGPT Plugin 的本质是 OpenAI 在收集数据? [85:21] 中国的大模型公司如何追赶 OpenAI? [90:05] 大模型能处理的 Context Length (背景信息长度)是能力瓶颈吗?要如何突破? [96:11] 如何理解 context length 对于大模型能力的重要性?需要对模型架构本身做改变吗? [103:53] 为什么说AI创新要赢得市场,生态可能比技术更重要? [106:04] AI技术应用落地的现状如何?有什么机会和挑战? [113:34] AI创业公司应该优先服务500强大客户吗? [118:56] 企业会如何使用AI:调用 API 还是本地部署?有哪些决定因素? [122:21] AI 应用创业有哪些方向?为什么说要关注 mission impossible (不可能的任务)? [130:15] 嘉宾眼里,AI 最让人兴奋的未来是什么? 免责:节目中的观点都是嘉宾和主持人个人观点,不代表所在机构观点,亦不构成任何投资建议。 参考文章 论文 《GPT-4,通用人工智能的火花》 Language models can explain neurons in language models Draw a unicorn in TikZ
GPT 之后,我们定义智能的方式发生了哪些改变,关于智能的探讨又上升了到哪一个阶段? GPT 与一代代语言模型的迭代与进步,或许真的让 AI 的未来看不到天花板。但如果走向通用人工智能时代是一个大概率事件,那么实现通用人工智能的最佳路径只有 GPT 吗?还有哪些值得大家去探索的方向有待讨论,探索的方法论又从何而来? 本期节目,徐老师、Monica 与来自微软的科学家们一起深度探讨,在通用人工智能时代与GPT话题不断的今天,AI 科学家与从业者还应该持续思考的核心问题究竟是什么。 同时,这也是 Monica 履新后一期「科技早知道」与「OnBoard!」的再度串台。 本期人物 硅谷徐老师,硅谷连续创业者、人工智能高管、斯坦福商学院客座讲师,「科技早知道」主播 |推特:@H0wieXu| 微信公众号:硅谷云| AI博客:howiexu.substack.com Monica,真格基金投资人,ex-AWS AI, 公众号:M小姐研习录,播客「OnBoard!」 主理人 谭旭,微软亚洲研究院 高级研究员,主要研究方向为生成式人工智能及其在语言/语音/音乐生成中的应用,《MSRA researcher, HuggingGPT (https://arxiv.org/abs/2303.17580)》作者之一 张弋,微软亚洲研究院 高级研究员,主要研究方向为通用人工智能的物理、数学,《Microsoft researcher,Sparks of AGI (https://arxiv.org/abs/2303.12712)》 论文作者之一 红博士,某 AI 公司研发总监,研究方向:计算机视觉、数据压缩、通用人工智能。公众号:红博士说 主要话题 [07:48] 第一视角解读「通用人工智能的火花」 [16:35] New Bing做了哪些取舍? [33:21] GPT-4 与 Auto-GPT 哪个更好? [47:05] 能战胜 GPT 会是? [63:11] 如何打造更好的行业生态? [72:22] 过往经验如何在新 AI 浪潮里复用? 延伸阅读 - 论文 《GPT-4,通用人工智能的火花》 (https://arxiv.org/abs/2303.12712) - Language models can explain neurons in language models (https://openai.com/research/language-models-can-explain-neurons-in-language-models) - Draw a unicorn in TikZ
In this episode, we talk to Professor Niro Siriwardena, Professor of Primary and Pre-hospital Health care at the School of Health and Social Care at the University of Lincoln. Title of paper: Academic performance of ethnic minority versus White doctors in the MRCGP assessment 2016-2021: cross sectional studyAvailable at: https://doi.org/10.3399/BJGP.2022.0474Differential attainment is widely found in undergraduate and postgraduate medical examinations. It has been suggested that subjective bias due to racial in discrimination clinical skills assessments may be a cause of examination failure for UK trained ethnic minority candidates and international medical graduates. No previous study has examined differential attainment in all components of GP licensing assessments including workplace-based assessment, taking into account scores at selection in GP specialty training. Ethnicity did not reduce the chance of passing GP licensing tests once Sex, place of primary medical qualification, declared disability and selection (multispecialty recruitment assessment) scores were taken into account. Doctors admitted to GP speciality training who are in the lowest MSRA score bands may need additional support during training to maximise their chances of achieving licensing regardless of their ethnicity or other demographic characteristics.
This week: special session update, outdoor tourism sustainability, MSRA's Back to the 50s car show returns, Northwoods League baseball Part II
Alexander Fleming discovered penicillin 1928 and it became available for widespread use in 1945. Since then people have benefited from the use of antibiotics in curing infections that would have previously sent them to their graves. Now, however, this golden age is coming to an end. Top researchers state that we are entering into the post-antibiotic era. Superbugs such as MSRA and CRE are on the rise and becoming increasingly difficult -- if not downright impossible -- to treat with our...
Alexander Fleming discovered penicillin 1928 and it became available for widespread use in 1945. Since then people have benefited from the use of antibiotics in curing infections that would have previously sent them to their graves. Now, however, this golden age is coming to an end. Top researchers state that we are entering into the post-antibiotic era. Superbugs such as MSRA and CRE are on the rise and becoming increasingly difficult -- if not downright impossible -- to treat with our...
Alexander Fleming discovered penicillin 1928 and it became available for widespread use in 1945. Since then people have benefited from the use of antibiotics in curing infections that would have previously sent them to their graves. Now, however, this golden age is coming to an end. Top researchers state that we are entering into the post-antibiotic era. Superbugs such as MSRA and CRE are on the rise and becoming increasingly difficult -- if not downright impossible -- to treat with our...
With a quick apology for being absent recently, Dan returns (minus one tooth) in good spirits as usual. He's just in time, because we have two fantastic guests lined up today! Listen in to hear more about them.
Voyomotive (@Voyomotive) CEO Peter Yorke talks with Dan about the scanning/diagnostics feature that comes with Voyo. Not only does it have access to the generic codes that most scanners do, it can read proprietary ones that would normally be out of your reach.
With all this talk about car technology, Dan thanks his lucky stars that none of it was available when he was young and reckless. He also recalls two police run-ins that, thank goodness, were more misunderstandings than anything else.
The technology that is constantly emerging in our lives is incredible. Soon to be released is the latest innovation in after-market car tech: Voyo (@Voyomotive), the world's most advanced connected car technology. Not only can it track where a vehicle has been, it can also unlock it via your phone, troubleshoot issues, and detect speeding. On top of everything, it's affordable. $100 for a base model, and only a small amount more for added features.
Half the fun of being a car lover is checking out someone else's ride. Minnesota is home to a fantastic car show that brings together 12,000 street rods; it's practically a buffet! Then, satisfy both your automotive and techie side with Voyo, an amazing little gadget that opens up a world of new interactions between you and your car. Segment 1: The Root of the Problem Segment 2: A Gathering of Greatness Segment 3: Coming Soon Segment 4: Voyomotive Segment 5: Diagnostics Tech Segment 6: Face to Face with the Law
Dale Sohlstrom gives us the details on MSRA's Back to the Fifties weekend that runs from June 17th to June 19th. Visit their website for additional information on the hours, events, and more!
Wondering where you can find 12,000 of the country's greatest and oldest street rodders? Look no farther than the Minnesota Street Rod Association's Back to the Fifties weekend, an annual event that started back in 1974. Dale Sohlstrom, a member of the MSRA Board of Directors, joins us to share more information about this larger than life event.
Frankly Speaking About Cancer with the Cancer Support Community
Living with cancer can be a challenge for anyone—but what if you also have an intellectual or developmental disability? On this episode of Frankly Speaking About Cancer, we will explore the unique challenges people with intellectual or developmental disabilities, their caregivers and their health care teams face when it comes to cancer prevention, screening and treatment. Show host Linda House, RN, of the Cancer Support Community, will be joined by Robyn J. Blanchard, RN, of The Arc Gloucester; Leone Murphy, MSN, RN, of The Arc of New Jersey; and Karen Luken, MSRA, of the North Carolina Office on Disability and Health.
This is fascinating stuff. A 1000 year old recipe from a 10th Century Anglo-Saxon medical book, as far as medical books went in the 10th Century, contains a potion which appears to be able to kill the MSRA (as well as other) antibiotic-resistant superbug. I'll be speaking with Dr. Jay Keystone, tropical infectious diseases specialist at Toronto General Hospital about this development. 21st Century medicine taking a backseat to 10th Century potions. What are the implications? I'm sure there will be many saying “told you!” By the way, how did ‘they' (Today's med researchers) find out this potion of garlic, onion or leak, wine and Oxgall (bile from a cow's stomach) would thump MSRA? Everything, except the oxgall, could appear on or beside your dinner tonight. See omnystudio.com/listener for privacy information.
Methicillin-resistant Staphylococcus aureus (MSRA) has become a global public health problem. In a world where antibiotics are failing us, is there a chance to stop it?
Frankly Speaking About Cancer with the Cancer Support Community
Living with cancer can be a challenge for anyone—but what if you also have an intellectual or developmental disability? On this episode of Frankly Speaking About Cancer, we will explore the unique challenges people with intellectual or developmental disabilities, their caregivers and their health care teams face when it comes to cancer prevention, screening and treatment. Show host Linda House, RN, of the Cancer Support Community, will be joined by Robyn J. Blanchard, RN, of The Arc Gloucester; Leone Murphy, MSN, RN, of The Arc of New Jersey; and Karen Luken, MSRA, of the North Carolina Office on Disability and Health.
Back in town with real internet and talking about some scuab. Some of the stories this week in the news... April Fools, Scuab Rights, Overly Hot Gear, Scuba Diving Hall of Fame, The High School Scuba, Ocean Day, Lost and Found, Pile of History, and MSRA & NUMA Find. Also some potentially cool gear with Rocket to the Seas and DAN Store. Scuba News in Hisory... which year was it? And last but not least the bad scuba joke.
Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new genetic loci for obesity. Here we aimed to discover additional obesity loci in extremely obese children and adolescents. We also investigated if these results generalize by estimating the effects of these obesity loci in adults and in population-based samples including both children and adults. We jointly analysed two GWAS of 2,258 individuals and followed-up the best, according to lowest p-values, 44 single nucleotide polymorphisms (SNP) from 21 genomic regions in 3,141 individuals. After this DISCOVERY step, we explored if the findings derived from the extremely obese children and adolescents (10 SNPs from 5 genomic regions) generalized to (i) the population level and (ii) to adults by genotyping another 31,182 individuals (GENERALIZATION step). Apart from previously identified FTO, MC4R, and TMEM18, we detected two new loci for obesity: one in SDCCAG8 (serologically defined colon cancer antigen 8 gene; p = 1.85610 x 10(-8) in the DISCOVERY step) and one between TNKS (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase gene) and MSRA (methionine sulfoxide reductase A gene; p = 4.84 x 10(-7)), the latter finding being limited to children and adolescents as demonstrated in the GENERALIZATION step. The odds ratios for early-onset obesity were estimated at similar to 1.10 per risk allele for both loci. Interestingly, the TNKS/MSRA locus has recently been found to be associated with adult waist circumference. In summary, we have completed a meta-analysis of two GWAS which both focus on extremely obese children and adolescents and replicated our findings in a large followed-up data set. We observed that genetic variants in or near FTO, MC4R, TMEM18, SDCCAG8, and TNKS/MSRA were robustly associated with early-onset obesity. We conclude that the currently known major common variants related to obesity overlap to a substantial degree between children and adults.